Year |
Citation |
Score |
2023 |
Maji A, Soutar CP, Zhang J, Lewandowska A, Uno BE, Yan S, Shelke Y, Murhade G, Nimerovsky E, Borcik CG, Arango AS, Lange JD, Marin-Toledo JP, Lyu Y, Bailey KL, ... ... Burke MD, et al. Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal. Nature. PMID 37938782 DOI: 10.1038/s41586-023-06710-4 |
0.75 |
|
2022 |
Angello NH, Rathore V, Beker W, Wołos A, Jira ER, Roszak R, Wu TC, Schroeder CM, Aspuru-Guzik A, Grzybowski BA, Burke MD. Closed-loop optimization of general reaction conditions for heteroaryl Suzuki-Miyaura coupling. Science (New York, N.Y.). 378: 399-405. PMID 36302014 DOI: 10.1126/science.adc8743 |
0.749 |
|
2022 |
Ranoa DRE, Holland RL, Alnaji FG, Green KJ, Wang L, Fredrickson RL, Wang T, Wong GN, Uelmen J, Maslov S, Weiner ZJ, Tkachenko AV, Zhang H, Liu Z, Ibrahim A, ... ... Burke MD, et al. Mitigation of SARS-CoV-2 transmission at a large public university. Nature Communications. 13: 3207. PMID 35680861 DOI: 10.1038/s41467-022-30833-3 |
0.44 |
|
2022 |
Beker W, Roszak R, Wołos A, Angello NH, Rathore V, Burke MD, Grzybowski BA. Machine Learning May Sometimes Simply Capture Literature Popularity Trends: A Case Study of Heterocyclic Suzuki-Miyaura Coupling. Journal of the American Chemical Society. 144: 4819-4827. PMID 35258973 DOI: 10.1021/jacs.1c12005 |
0.743 |
|
2020 |
Kelly AM, Chen PJ, Klubnick J, Blair DJ, Burke MD. A Mild Method for Making MIDA Boronates. Organic Letters. PMID 32841037 DOI: 10.1021/Acs.Orglett.0C02449 |
0.354 |
|
2020 |
Hou J, Daniels PN, Burke MD. Small Molecule Channels Harness Membrane Potential to Concentrate Potassium in trk1Δtrk2Δ Yeast. Acs Chemical Biology. PMID 32427463 DOI: 10.1021/Acschembio.0C00180 |
0.38 |
|
2020 |
Blair DJ, Burke MD. A Computer Conquers Tactical Combinations Chem. 6: 12-13. DOI: 10.1016/J.Chempr.2019.12.019 |
0.317 |
|
2019 |
Jo YI, Burke MD, Cheon CH. Modular Syntheses of Phenanthroindolizidine Natural Products. Organic Letters. PMID 31117710 DOI: 10.1021/Acs.Orglett.9B01397 |
0.358 |
|
2019 |
Lehmann JW, Crouch IT, Blair DJ, Trobe M, Wang P, Li J, Burke MD. Axial shielding of Pd(II) complexes enables perfect stereoretention in Suzuki-Miyaura cross-coupling of Csp boronic acids. Nature Communications. 10: 1263. PMID 30894535 DOI: 10.1038/S41467-019-09249-Z |
0.636 |
|
2019 |
Muraglia KA, Chorghade RS, Kim BR, Tang XX, Shah VS, Grillo AS, Daniels PN, Cioffi AG, Karp PH, Zhu L, Welsh MJ, Burke MD. Small-molecule ion channels increase host defences in cystic fibrosis airway epithelia. Nature. PMID 30867598 DOI: 10.1038/S41586-019-1018-5 |
0.777 |
|
2018 |
Haley HMS, Hill AG, Greenwood AI, Woerly EM, Rienstra CM, Burke MD. Peridinin Is an Exceptionally Potent and Membrane-Embedded Inhibitor of Bilayer Lipid Peroxidation. Journal of the American Chemical Society. PMID 30388000 DOI: 10.1021/Jacs.8B06933 |
0.802 |
|
2018 |
Yien YY, Shi J, Chen C, Cheung JT, Grillo AS, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King MJ, Ablain J, Li H, Zon L, Palis J, ... Burke MD, et al. FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity. The Journal of Biological Chemistry. PMID 30366982 DOI: 10.1074/Jbc.Ra118.002742 |
0.533 |
|
2018 |
Lehmann JW, Blair DJ, Burke MD. Toward Generalization of Iterative Small Molecule Synthesis. Nature Reviews. Chemistry. 2. PMID 29696152 DOI: 10.1038/s41570-018-0115 |
0.31 |
|
2018 |
Trobe M, Burke MD. The Molecular Industrial Revolution: Automated Synthesis of Small Molecules. Angewandte Chemie (International Ed. in English). PMID 29513400 DOI: 10.1002/Anie.201710482 |
0.37 |
|
2018 |
Della Ripa LA, Petros ZA, Cioffi AG, Piehl DW, Courtney JM, Burke MD, Rienstra CM. Solid-State NMR of Highly 13C-Enriched Cholesterol in Lipid Bilayers. Methods (San Diego, Calif.). PMID 29366688 DOI: 10.1016/J.Ymeth.2018.01.008 |
0.773 |
|
2018 |
Yien YY, Shi J, Chen C, Cheung J, Grillo A, Shrestha R, Li L, Zhang X, Kafina MD, Kingsley PD, King M, Ablain J, Zon LI, Palis J, Burke M, et al. Target of Erythropoietin, Fam210b, Regulates Erythroid Heme Synthesis By Control of Mitochondrial Iron Import and Regulation of Fech Activity Blood. 132: 849-849. DOI: 10.1182/Blood-2018-99-120299 |
0.54 |
|
2017 |
Palazzolo AME, Simons CLW, Burke MD. The natural productome. Proceedings of the National Academy of Sciences of the United States of America. PMID 28533417 DOI: 10.1073/Pnas.1706266114 |
0.323 |
|
2017 |
Grillo AS, SantaMaria AM, Kafina MD, Cioffi AG, Huston NC, Han M, Seo YA, Yien YY, Nardone C, Menon AV, Fan J, Svoboda DC, Anderson JB, Hong JD, Nicolau BG, ... ... Burke MD, et al. Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals. Science (New York, N.Y.). 356: 608-616. PMID 28495746 DOI: 10.1126/Science.Aah3862 |
0.764 |
|
2016 |
Gonzalez JA, Ogba OM, Morehouse GF, Rosson N, Houk KN, Leach AG, Cheong PH, Burke MD, Lloyd-Jones GC. MIDA boronates are hydrolysed fast and slow by two different mechanisms. Nature Chemistry. 8: 1067-1075. PMID 27768100 DOI: 10.1038/Nchem.2571 |
0.319 |
|
2016 |
Della Ripa LA, Cioffi AG, Phinney S, Shi X, Pogorelov TV, Burke MD, Rienstra CM. Atomic Resolution Studies of Sterol Interactions by Solid-State NMR Spectroscopy Biophysical Journal. 110: 36a. DOI: 10.1016/J.Bpj.2015.11.260 |
0.323 |
|
2015 |
Davis SA, Della Ripa LA, Hu L, Cioffi AG, Pogorelov TV, Rienstra CM, Burke MD. The C3-OH of Amphotericin B Plays an Important Role in Ion Conductance. Journal of the American Chemical Society. PMID 26580003 DOI: 10.1021/Jacs.5B05766 |
0.798 |
|
2015 |
Cioffi AG, Hou J, Grillo AS, Diaz KA, Burke MD. Restored Physiology in Protein-Deficient Yeast by a Small Molecule Channel. Journal of the American Chemical Society. 137: 10096-9. PMID 26230309 DOI: 10.1021/Jacs.5B05765 |
0.797 |
|
2015 |
Li J, Grillo AS, Burke MD. From Synthesis to Function via Iterative Assembly of N-Methyliminodiacetic Acid Boronate Building Blocks. Accounts of Chemical Research. PMID 26200460 DOI: 10.1021/Acs.Accounts.5B00128 |
0.751 |
|
2015 |
Davis SA, Vincent BM, Endo MM, Whitesell L, Marchillo K, Andes DR, Lindquist S, Burke MD. Nontoxic antimicrobials that evade drug resistance. Nature Chemical Biology. 11: 481-7. PMID 26030729 DOI: 10.1038/Nchembio.1821 |
0.772 |
|
2015 |
Li J, Ballmer SG, Gillis EP, Fujii S, Schmidt MJ, Palazzolo AM, Lehmann JW, Morehouse GF, Burke MD. Synthesis of many different types of organic small molecules using one automated process. Science (New York, N.Y.). 347: 1221-6. PMID 25766227 DOI: 10.1126/Science.Aaa5414 |
0.785 |
|
2015 |
Endo MM, Cioffi AG, Burke MD. Our Path to Less Toxic Amphotericins Synlett. DOI: 10.1055/S-0035-1560800 |
0.811 |
|
2014 |
Woerly EM, Roy J, Burke MD. Synthesis of most polyene natural product motifs using just 12 building blocks and one coupling reaction Nature Chemistry. 6: 484-491. PMID 24848233 DOI: 10.1038/Nchem.1947 |
0.82 |
|
2014 |
Anderson TM, Clay MC, Cioffi AG, Diaz KA, Hisao GS, Tuttle MD, Nieuwkoop AJ, Comellas G, Maryum N, Wang S, Uno BE, Wildeman EL, Gonen T, Rienstra CM, Burke MD. Amphotericin forms an extramembranous and fungicidal sterol sponge. Nature Chemical Biology. 10: 400-6. PMID 24681535 DOI: 10.1038/Nchembio.1496 |
0.787 |
|
2014 |
Woerly EM, Roy J, Burke MD. Erratum: Synthesis of most polyene natural product motifs using just 12 building blocks and one coupling reaction [Nature Chemistry 6, 484-491 (2014), 10.1038/nchem.1975] Nature Chemistry. 6. DOI: 10.1038/Nchem.1975 |
0.8 |
|
2013 |
Woerly EM, Miller JE, Burke MD. (1-bromovinyl)-MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis. Tetrahedron. 69. PMID 24347693 DOI: 10.1016/J.Tet.2013.05.050 |
0.812 |
|
2013 |
Wilcock BC, Endo MM, Uno BE, Burke MD. C2'-OH of amphotericin B plays an important role in binding the primary sterol of human cells but not yeast cells. Journal of the American Chemical Society. 135: 8488-91. PMID 23718627 DOI: 10.1021/Ja403255S |
0.758 |
|
2012 |
Wilcock BC, Uno BE, Bromann GL, Clark MJ, Anderson TM, Burke MD. Electronic tuning of site-selectivity. Nature Chemistry. 4: 996-1003. PMID 23174979 DOI: 10.1038/Nchem.1495 |
0.769 |
|
2012 |
Gray KC, Palacios DS, Dailey I, Endo MM, Uno BE, Wilcock BC, Burke MD. Amphotericin primarily kills yeast by simply binding ergosterol. Proceedings of the National Academy of Sciences of the United States of America. 109: 2234-9. PMID 22308411 DOI: 10.1073/Pnas.1117280109 |
0.746 |
|
2012 |
Dick GR, Woerly EM, Burke MD. A general solution for the 2-pyridyl problem Angewandte Chemie - International Edition. 51: 2667-2672. PMID 22287537 DOI: 10.1002/Anie.201108608 |
0.775 |
|
2011 |
Woerly EM, Struble JR, Palyam N, O'Hara SP, Burke MD. (Z)-(2-bromovinyl)-MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis. Tetrahedron. 67: 4333-4343. PMID 22753994 DOI: 10.1016/J.Tet.2011.04.021 |
0.809 |
|
2011 |
Li J, Burke MD. Pinene-derived iminodiacetic acid (PIDA): A powerful ligand for stereoselective synthesis and iterative cross-coupling of C(sp 3) boronate building blocks Journal of the American Chemical Society. 133: 13774-13777. PMID 21823591 DOI: 10.1021/Ja205912Y |
0.621 |
|
2011 |
Fujii S, Chang SY, Burke MD. Total synthesis of synechoxanthin through iterative cross-coupling Angewandte Chemie - International Edition. 50: 7862-7864. PMID 21681879 DOI: 10.1002/Anie.201102688 |
0.665 |
|
2011 |
Palacios DS, Dailey I, Siebert DM, Wilcock BC, Burke MD. Synthesis-enabled functional group deletions reveal key underpinnings of amphotericin B ion channel and antifungal activities Proceedings of the National Academy of Sciences of the United States of America. 108: 6733-6738. PMID 21368185 DOI: 10.1073/Pnas.1015023108 |
0.777 |
|
2011 |
Fujii S, Chang SY, Burke MD. Synthesis of Synechoxanthin Synfacts. 2011: 1161-1161. DOI: 10.1055/S-0031-1289272 |
0.338 |
|
2011 |
Woerly EM, Struble JR, Palyam N, O'Hara SP, Burke MD. (Z)-(2-bromovinyl)-MIDA boronate: A readily accessible and highly versatile building block for small molecule synthesis Tetrahedron. 67: 4333-4343. DOI: 10.1016/j.tet.2011.04.021 |
0.799 |
|
2011 |
Fujii S, Chang SY, Burke MD. Cover Picture: Total Synthesis of Synechoxanthin through Iterative Cross-Coupling (Angew. Chem. Int. Ed. 34/2011) Angewandte Chemie International Edition. 50: 7705-7705. DOI: 10.1002/Anie.201104526 |
0.587 |
|
2011 |
Fujii S, Chang SY, Burke MD. Titelbild: Total Synthesis of Synechoxanthin through Iterative Cross-Coupling (Angew. Chem. 34/2011) Angewandte Chemie. 123: 7849-7849. DOI: 10.1002/Ange.201104526 |
0.59 |
|
2010 |
Lee SJ, Anderson TM, Burke MD. A simple and general platform for generating stereochemically complex polyene frameworks by iterative cross-coupling. Angewandte Chemie (International Ed. in English). 49: 8860-3. PMID 20927795 DOI: 10.1002/Anie.201004911 |
0.612 |
|
2010 |
Dick GR, Knapp DM, Gillis EP, Burke MD. General method for synthesis of 2-heterocyclic N-methyliminodiacetic acid boronates Organic Letters. 12: 2314-2317. PMID 20465293 DOI: 10.1021/Ol100671V |
0.774 |
|
2010 |
Woerly EM, Cherney AH, Davis EK, Burke MD. Stereoretentive suzuki-miyaura coupling of haloallenes enables fully stereocontrolled access to (-)-Peridinin Journal of the American Chemical Society. 132: 6941-6943. PMID 20441218 DOI: 10.1021/Ja102721P |
0.823 |
|
2010 |
Woerly EM, Cherney AH, Davis EK, Burke MD. Stereoretentive Suzuki-Miyaura Coupling of Haloallenes Synfacts. 2010: 933-933. DOI: 10.1055/S-0030-1257753 |
0.773 |
|
2010 |
Struble JR, Lee SJ, Burke MD. Ethynyl MIDA boronate: A readily accessible and highly versatile building block for small molecule synthesis Tetrahedron. 66: 4710-4718. DOI: 10.1016/j.tet.2010.04.020 |
0.804 |
|
2010 |
Woerly EM, Cherney AH, Davis EK, Burke MD. ChemInform Abstract: Stereoretentive Suzuki-Miyaura Coupling of Haloallenes Enables Fully Stereocontrolled Access to (-)-Peridinin (Ib). Cheminform. 41: no-no. DOI: 10.1002/chin.201043207 |
0.774 |
|
2009 |
Gillis EP, Burke MD. Iterative Cross-Couplng with MIDA Boronates: Towards a General Platform for Small Molecule Synthesis. Aldrichimica Acta. 42: 17-27. PMID 22523433 |
0.746 |
|
2009 |
Knapp DM, Gillis EP, Burke MD. A general solution for unstable boronic acids: Slow-release cross-coupling from air-stable MIDA boronates Journal of the American Chemical Society. 131: 6961-6963. PMID 19405470 DOI: 10.1021/Ja901416P |
0.793 |
|
2009 |
Burke MD. Flexible tetracycline synthesis yields promising antibiotics Nature Chemical Biology. 5: 77-79. PMID 19148174 DOI: 10.1038/Nchembio0209-77 |
0.341 |
|
2009 |
Uno BE, Gillis EP, Burke MD. Vinyl MIDA boronate: a readily accessible and highly versatile building block for small molecule synthesis Tetrahedron. 65: 3130-3138. DOI: 10.1016/j.tet.2008.11.010 |
0.813 |
|
2009 |
Ballmer SG, Gillis EP, Burke MD, Morton D, Davies HML. B-protected haloboronic acids for iterative cross-coupling Organic Syntheses. 86: 344-359. DOI: 10.1002/0471264229.Os086.33 |
0.768 |
|
2009 |
Ballmer SG, Gillis EP, Burke MD, Morton D, Davies HML. B-protected haloboronic acids for iterative cross-coupling Organic Syntheses. 86: 344-359. |
0.775 |
|
2009 |
Gillis EP, Burke MD. Iterative cross-coupling with MIDA boronates: Towards a general strategy for small-molecule synthesis Aldrichimica Acta. 42: 17-27. |
0.752 |
|
2008 |
Gillis EP, Burke MD. Multistep synthesis of complex boronic acids from simple MIDA boronates Journal of the American Chemical Society. 130: 14084-14085. PMID 18837550 DOI: 10.1021/Ja8063759 |
0.764 |
|
2008 |
Suk JL, Gray KC, Paek JS, Burke MD. Simple, efficient, and modular syntheses of polyene natural products via iterative cross-coupling Journal of the American Chemical Society. 130: 466-468. PMID 18081295 DOI: 10.1021/Ja078129X |
0.819 |
|
2007 |
Palacios DS, Anderson TM, Burke MD. A post-PKS oxidation of the amphotericin B skeleton predicted to be critical for channel formation is not required for potent antifungal activity. Journal of the American Chemical Society. 129: 13804-5. PMID 17956100 DOI: 10.1021/Ja075739O |
0.807 |
|
2007 |
Gillis EP, Burke MD. A simple and modular strategy for small molecule synthesis: Iterative Suzuki-Miyaura coupling of B-protected haloboronic acid building blocks Journal of the American Chemical Society. 129: 6716-6717. PMID 17488084 DOI: 10.1021/Ja0716204 |
0.783 |
|
2004 |
Burke MD, Berger EM, Schreiber SL. A synthesis strategy yielding skeletally diverse small molecules combinatorially. Journal of the American Chemical Society. 126: 14095-104. PMID 15506774 DOI: 10.1021/Ja0457415 |
0.521 |
|
2004 |
Burke MD, Schreiber SL. A planning strategy for diversity-oriented synthesis. Angewandte Chemie (International Ed. in English). 43: 46-58. PMID 14694470 DOI: 10.1002/Anie.200300626 |
0.515 |
|
2004 |
Burke MD, Schreiber SL. Eine Strategie für die Diversitäts-orientierte Synthese Angewandte Chemie. 116: 48-60. DOI: 10.1002/Ange.200300626 |
0.431 |
|
2003 |
Burke MD, Berger EM, Schreiber SL. Generating diverse skeletons of small molecules combinatorially. Science (New York, N.Y.). 302: 613-8. PMID 14576427 DOI: 10.1126/Science.1089946 |
0.548 |
|
2003 |
Kohli RM, Burke MD, Tao J, Walsh CT. Chemoenzymatic route to macrocyclic hybrid peptide/polyketide-like molecules. Journal of the American Chemical Society. 125: 7160-1. PMID 12797773 DOI: 10.1021/Ja0352202 |
0.372 |
|
2001 |
White MC, Burke MD, Peleg S, Brem H, Posner GH. Conformationally restricted hybrid analogues of the hormone 1 alpha,25-dihydroxyvitamin D(3): design, synthesis, and biological evaluation. Bioorganic & Medicinal Chemistry. 9: 1691-9. PMID 11425569 DOI: 10.1016/S0968-0896(01)00087-6 |
0.404 |
|
1998 |
Posner GH, Lee JK, Wang Q, Peleg S, Burke M, Brem H, Dolan P, Kensler TW. Noncalcemic, antiproliferative, transcriptionally active, 24-fluorinated hybrid analogues of the hormone 1alpha, 25-dihydroxyvitamin D3. Synthesis and preliminary biological evaluation. Journal of Medicinal Chemistry. 41: 3008-14. PMID 9685240 DOI: 10.1021/Jm980031T |
0.408 |
|
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