David Botstein - Publications

Affiliations: 
1967-1987 Massachusetts Institute of Technology, Cambridge, MA, United States 
 1987-1990 Genentech, Inc. 
 1990-2003 Stanford University, Palo Alto, CA 
 2003- Princeton University, Princeton, NJ 
 2013- Calico Life Sciences, LLC 
Area:
Genomics
Website:
http://molbio.princeton.edu/faculty/molbio-faculty/96-botstein

235 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Bradley PH, Gibney PA, Botstein D, Troyanskaya OG, Rabinowitz JD. Minor Isozymes Tailor Yeast Metabolism to Carbon Availability. Msystems. 4. PMID 30834327 DOI: 10.1128/mSystems.00170-18  0.84
2018 Xu YF, Lu W, Chen JC, Johnson SA, Gibney PA, Thomas DG, Brown G, May AL, Campagna SR, Yakunin AF, Botstein D, Rabinowitz JD. Discovery and functional characterization of a yeast sugar alcohol phosphatase. Acs Chemical Biology. PMID 30240188 DOI: 10.1021/acschembio.8b00804  0.84
2018 Gibney PA, Schieler A, Chen JC, Bacha-Hummel JM, Botstein M, Volpe M, Silverman SJ, Xu Y, Bennett BD, Rabinowitz JD, Botstein D. Common and Divergent Features of Galactose-1-phosphate and Fructose-1-phosphate Toxicity in Yeast. Molecular Biology of the Cell. PMID 29444955 DOI: 10.1091/mbc.E17-11-0666  0.84
2016 Hackett SR, Zanotelli VR, Xu W, Goya J, Park JO, Perlman DH, Gibney PA, Botstein D, Storey JD, Rabinowitz JD. Systems-level analysis of mechanisms regulating yeast metabolic flux. Science (New York, N.Y.). 354. PMID 27789812 DOI: 10.1126/science.aaf2786  0.84
2016 Møller HD, Bojsen RK, Tachibana C, Parsons L, Botstein D, Regenberg B. Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells. Journal of Visualized Experiments : Jove. PMID 27077531 DOI: 10.3791/54239  0.48
2015 Reavey CT, Hickman MJ, Dobi KC, Botstein D, Winston F. Analysis of Polygenic Mutants Suggests a Role for Mediator in Regulating Transcriptional Activation Distance in Saccharomyces cerevisiae. Genetics. 201: 599-612. PMID 26281848 DOI: 10.1534/genetics.115.181164  0.4
2015 Møller HD, Parsons L, Jørgensen TS, Botstein D, Regenberg B. Extrachromosomal circular DNA is common in yeast. Proceedings of the National Academy of Sciences of the United States of America. 112: E3114-22. PMID 26038577 DOI: 10.1073/pnas.1508825112  1
2015 Gibney PA, Schieler A, Chen JC, Rabinowitz JD, Botstein D. Characterizing the in vivo role of trehalose in Saccharomyces cerevisiae using the AGT1 transporter. Proceedings of the National Academy of Sciences of the United States of America. 112: 6116-21. PMID 25918382 DOI: 10.1073/pnas.1506289112  1
2014 Botstein D. Lasker∼Koshland to genetics pioneer. Cell. 158: 1230-2. PMID 25215481 DOI: 10.1016/j.cell.2014.08.020  1
2014 McIsaac RS, Gibney PA, Chandran SS, Benjamin KR, Botstein D. Synthetic biology tools for programming gene expression without nutritional perturbations in Saccharomyces cerevisiae. Nucleic Acids Research. 42: e48. PMID 24445804 DOI: 10.1093/nar/gkt1402  1
2013 McIsaac RS, Oakes BL, Botstein D, Noyes MB. Rapid synthesis and screening of chemically activated transcription factors with GFP-based reporters. Journal of Visualized Experiments : Jove. e51153. PMID 24300440 DOI: 10.3791/51153  1
2013 Gibney PA, Lu C, Caudy AA, Hess DC, Botstein D. Yeast metabolic and signaling genes are required for heat-shock survival and have little overlap with the heat-induced genes. Proceedings of the National Academy of Sciences of the United States of America. 110: E4393-402. PMID 24167267 DOI: 10.1073/pnas.1318100110  1
2013 Lang GI, Rice DP, Hickman MJ, Sodergren E, Weinstock GM, Botstein D, Desai MM. Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations. Nature. 500: 571-4. PMID 23873039 DOI: 10.1038/nature12344  1
2013 Caudy AA, Guan Y, Jia Y, Hansen C, DeSevo C, Hayes AP, Agee J, Alvarez-Dominguez JR, Arellano H, Barrett D, Bauerle C, Bisaria N, Bradley PH, Breunig JS, Bush E, ... ... Botstein D, et al. A new system for comparative functional genomics of Saccharomyces yeasts. Genetics. 195: 275-87. PMID 23852385 DOI: 10.1534/genetics.113.152918  1
2013 McIsaac RS, Silverman SJ, Parsons L, Xu P, Briehof R, McClean MN, Botstein D. Visualization and analysis of mRNA molecules using fluorescence in situ hybridization in Saccharomyces cerevisiae. Journal of Visualized Experiments : Jove. e50382. PMID 23793137 DOI: 10.3791/50382  1
2013 Gibney PA, Hickman MJ, Bradley PH, Matese JC, Botstein D. Phylogenetic portrait of the Saccharomyces cerevisiae functional genome. G3 (Bethesda, Md.). 3: 1335-40. PMID 23749449 DOI: 10.1534/g3.113.006585  1
2013 Reisser C, Dick C, Kruglyak L, Botstein D, Schacherer J, Hess D. Genetic Basis of Ammonium Toxicity Resistance in a Sake Strain of Yeast: A Mendelian Case. G3 (Bethesda, Md.). PMID 23550140 DOI: 10.1534/g3.113.005884  1
2013 Dolinski K, Botstein D. Automating the construction of gene ontologies. Nature Biotechnology. 31: 34-5. PMID 23302932 DOI: 10.1038/nbt.2476  1
2013 McIsaac RS, Oakes BL, Wang X, Dummit KA, Botstein D, Noyes MB. Synthetic gene expression perturbation systems with rapid, tunable, single-gene specificity in yeast. Nucleic Acids Research. 41: e57. PMID 23275543 DOI: 10.1093/nar/gks1313  1
2013 Welch AZ, Gibney PA, Botstein D, Koshland DE. TOR and RAS pathways regulate desiccation tolerance in Saccharomyces cerevisiae. Molecular Biology of the Cell. 24: 115-28. PMID 23171550 DOI: 10.1091/mbc.E12-07-0524  0.84
2013 Slavov N, Botstein D. Decoupling nutrient signaling from growth rate causes aerobic glycolysis and deregulation of cell size and gene expression. Molecular Biology of the Cell. 24: 157-68. PMID 23135997 DOI: 10.1091/mbc.E12-09-0670  1
2013 Botstein D. Foreword Plant Transposons and Genome Dynamics in Evolution. xi-xii. DOI: 10.1002/9781118500156  1
2012 Botstein D. Why we need more basic biology research, not less. Molecular Biology of the Cell. 23: 4160-1. PMID 23112227 DOI: 10.1091/mbc.E12-05-0406  1
2012 Doherty KM, Pride LD, Lukose J, Snydsman BE, Charles R, Pramanik A, Muller EG, Botstein D, Moore CW. Loss of a 20S proteasome activator in Saccharomyces cerevisiae downregulates genes important for genomic integrity, increases DNA damage, and selectively sensitizes cells to agents with diverse mechanisms of action. G3 (Bethesda, Md.). 2: 943-59. PMID 22908043 DOI: 10.1534/g3.112.003376  1
2012 McIsaac RS, Petti AA, Bussemaker HJ, Botstein D. Perturbation-based analysis and modeling of combinatorial regulation in the yeast sulfur assimilation pathway. Molecular Biology of the Cell. 23: 2993-3007. PMID 22696683 DOI: 10.1091/mbc.E12-03-0232  1
2012 Petti AA, McIsaac RS, Ho-Shing O, Bussemaker HJ, Botstein D. Combinatorial control of diverse metabolic and physiological functions by transcriptional regulators of the yeast sulfur assimilation pathway. Molecular Biology of the Cell. 23: 3008-24. PMID 22696679 DOI: 10.1091/mbc.E12-03-0233  1
2012 Slavov N, Airoldi EM, van Oudenaarden A, Botstein D. A conserved cell growth cycle can account for the environmental stress responses of divergent eukaryotes. Molecular Biology of the Cell. 23: 1986-97. PMID 22456505 DOI: 10.1091/mbc.E11-11-0961  1
2011 Botstein D, Fink GR. Yeast: an experimental organism for 21st Century biology. Genetics. 189: 695-704. PMID 22084421 DOI: 10.1534/genetics.111.130765  1
2011 Slavov N, Macinskas J, Caudy A, Botstein D. Metabolic cycling without cell division cycling in respiring yeast. Proceedings of the National Academy of Sciences of the United States of America. 108: 19090-5. PMID 22065748 DOI: 10.1073/pnas.1116998108  1
2011 Lang GI, Botstein D. A test of the coordinated expression hypothesis for the origin and maintenance of the GAL cluster in yeast. Plos One. 6: e25290. PMID 21966486 DOI: 10.1371/journal.pone.0025290  1
2011 McIsaac RS, Silverman SJ, McClean MN, Gibney PA, Macinskas J, Hickman MJ, Petti AA, Botstein D. Fast-acting and nearly gratuitous induction of gene expression and protein depletion in Saccharomyces cerevisiae. Molecular Biology of the Cell. 22: 4447-59. PMID 21965290 DOI: 10.1091/mbc.E11-05-0466  1
2011 Hickman MJ, Petti AA, Ho-Shing O, Silverman SJ, McIsaac RS, Lee TA, Botstein D. Coordinated regulation of sulfur and phospholipid metabolism reflects the importance of methylation in the growth of yeast. Molecular Biology of the Cell. 22: 4192-204. PMID 21900497 DOI: 10.1091/mbc.E11-05-0467  1
2011 Petti AA, Crutchfield CA, Rabinowitz JD, Botstein D. Survival of starving yeast is correlated with oxidative stress response and nonrespiratory mitochondrial function. Proceedings of the National Academy of Sciences of the United States of America. 108: E1089-98. PMID 21734149 DOI: 10.1073/pnas.1101494108  1
2011 Lang GI, Botstein D, Desai MM. Genetic variation and the fate of beneficial mutations in asexual populations. Genetics. 188: 647-61. PMID 21546542 DOI: 10.1534/genetics.111.128942  1
2011 Slavov N, Botstein D. Coupling among growth rate response, metabolic cycle, and cell division cycle in yeast. Molecular Biology of the Cell. 22: 1997-2009. PMID 21525243 DOI: 10.1091/mbc.E11-02-0132  1
2011 Botstein D. Genome-sequencing anniversary. Fruits of genome sequences for biology. Science (New York, N.Y.). 331: 1025. PMID 21350164 DOI: 10.1126/science.1204038  1
2011 Gresham D, Boer VM, Caudy A, Ziv N, Brandt NJ, Storey JD, Botstein D. System-level analysis of genes and functions affecting survival during nutrient starvation in Saccharomyces cerevisiae. Genetics. 187: 299-317. PMID 20944018 DOI: 10.1534/genetics.110.120766  1
2011 Silverman SJ, Petti AA, Slavov N, Parsons L, Briehof R, Thiberge SY, Zenklusen D, Gandhi SJ, Larson DR, Singer RH, Botstein D. Metabolic cycling in single yeast cells from unsynchronized steady-state populations limited on glucose or phosphate (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, (6946-6951) 10.1073/pnas.1002422107) Proceedings of the National Academy of Sciences of the United States of America. 108: 12185. DOI: 10.1073/pnas.1109536108  1
2010 Wyart M, Botstein D, Wingreen NS. Evaluating gene expression dynamics using pairwise RNA FISH data. Plos Computational Biology. 6: e1000979. PMID 21079668 DOI: 10.1371/journal.pcbi.1000979  1
2010 Botstein D. Technological innovation leads to fundamental understanding in cell biology. Molecular Biology of the Cell. 21: 3791-2. PMID 21079013 DOI: 10.1091/mbc.E10-04-0366  1
2010 Gresham D, Usaite R, Germann SM, Lisby M, Botstein D, Regenberg B. Adaptation to diverse nitrogen-limited environments by deletion or extrachromosomal element formation of the GAP1 locus. Proceedings of the National Academy of Sciences of the United States of America. 107: 18551-6. PMID 20937885 DOI: 10.1073/pnas.1014023107  1
2010 Silverman SJ, Petti AA, Slavov N, Parsons L, Briehof R, Thiberge SY, Zenklusen D, Gandhi SJ, Larson DR, Singer RH, Botstein D. Metabolic cycling in single yeast cells from unsynchronized steady-state populations limited on glucose or phosphate. Proceedings of the National Academy of Sciences of the United States of America. 107: 6946-51. PMID 20335538 DOI: 10.1073/pnas.1002422107  1
2010 Gresham D, Curry B, Ward A, Gordon DB, Brizuela L, Kruglyak L, Botstein D. Optimized detection of sequence variation in heterozygous genomes using DNA microarrays with isothermal-melting probes. Proceedings of the National Academy of Sciences of the United States of America. 107: 1482-7. PMID 20080586 DOI: 10.1073/pnas.0913883107  1
2010 Botstein D. It's the data! Molecular Biology of the Cell. 21: 4-6. PMID 20048255 DOI: 10.1091/mbc.E09-07-0575  1
2010 Engel SR, Balakrishnan R, Binkley G, Christie KR, Costanzo MC, Dwight SS, Fisk DG, Hirschman JE, Hitz BC, Hong EL, Krieger CJ, Livstone MS, Miyasato SR, Nash R, Oughtred R, ... ... Botstein D, et al. Saccharomyces Genome Database provides mutant phenotype data. Nucleic Acids Research. 38: D433-6. PMID 19906697 DOI: 10.1093/nar/gkp917  1
2010 Boer VM, Crutchfield CA, Bradley PH, Botstein D, Rabinowitz JD. Growth-limiting intracellular metabolites in yeast growing under diverse nutrient limitations. Molecular Biology of the Cell. 21: 198-211. PMID 19889834 DOI: 10.1091/mbc.E09-07-0597  1
2009 Salwinski L, Licata L, Winter A, Thorneycroft D, Khadake J, Ceol A, Aryamontri AC, Oughtred R, Livstone M, Boucher L, Botstein D, Dolinski K, Berardini T, Huala E, Tyers M, et al. Recurated protein interaction datasets. Nature Methods. 6: 860-1. PMID 19935838 DOI: 10.1038/nmeth1209-860  1
2009 Ho CH, Magtanong L, Barker SL, Gresham D, Nishimura S, Natarajan P, Koh JL, Porter J, Gray CA, Andersen RJ, Giaever G, Nislow C, Andrews B, Botstein D, Graham TR, et al. A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds. Nature Biotechnology. 27: 369-77. PMID 19349972 DOI: 10.1038/nbt.1534  1
2009 Lang GI, Murray AW, Botstein D. The cost of gene expression underlies a fitness trade-off in yeast. Proceedings of the National Academy of Sciences of the United States of America. 106: 5755-60. PMID 19299502 DOI: 10.1073/pnas.0901620106  1
2009 Airoldi EM, Huttenhower C, Gresham D, Lu C, Caudy AA, Dunham MJ, Broach JR, Botstein D, Troyanskaya OG. Predicting cellular growth from gene expression signatures. Plos Computational Biology. 5: e1000257. PMID 19119411 DOI: 10.1371/journal.pcbi.1000257  1
2009 Lu C, Brauer MJ, Botstein D. Slow growth induces heat-shock resistance in normal and respiratory-deficient yeast. Molecular Biology of the Cell. 20: 891-903. PMID 19056679 DOI: 10.1091/mbc.E08-08-0852  1
2008 Gresham D, Desai MM, Tucker CM, Jenq HT, Pai DA, Ward A, DeSevo CG, Botstein D, Dunham MJ. The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast. Plos Genetics. 4: e1000303. PMID 19079573 DOI: 10.1371/journal.pgen.1000303  1
2008 Boer VM, Amini S, Botstein D. Influence of genotype and nutrition on survival and metabolism of starving yeast. Proceedings of the National Academy of Sciences of the United States of America. 105: 6930-5. PMID 18456835 DOI: 10.1073/pnas.0802601105  1
2008 Gresham D, Dunham MJ, Botstein D. Comparing whole genomes using DNA microarrays. Nature Reviews. Genetics. 9: 291-302. PMID 18347592 DOI: 10.1038/nrg2335  1
2008 Hong EL, Balakrishnan R, Dong Q, Christie KR, Park J, Binkley G, Costanzo MC, Dwight SS, Engel SR, Fisk DG, Hirschman JE, Hitz BC, Krieger CJ, Livstone MS, Miyasato SR, ... ... Botstein D, et al. Gene Ontology annotations at SGD: new data sources and annotation methods. Nucleic Acids Research. 36: D577-81. PMID 17982175 DOI: 10.1093/nar/gkm909  1
2008 Brauer MJ, Huttenhower C, Airoldi EM, Rosenstein R, Matese JC, Gresham D, Boer VM, Troyanskaya OG, Botstein D. Coordination of growth rate, cell cycle, stress response, and metabolic activity in yeast. Molecular Biology of the Cell. 19: 352-67. PMID 17959824 DOI: 10.1091/mbc.E07-08-0779  1
2007 Heinicke S, Livstone MS, Lu C, Oughtred R, Kang F, Angiuoli SV, White O, Botstein D, Dolinski K. The Princeton Protein Orthology Database (P-POD): a comparative genomics analysis tool for biologists. Plos One. 2: e766. PMID 17712414 DOI: 10.1371/journal.pone.0000766  1
2007 Dolinski K, Botstein D. Orthology and functional conservation in eukaryotes. Annual Review of Genetics. 41: 465-507. PMID 17678444 DOI: 10.1146/annurev.genet.40.110405.090439  1
2007 Schacherer J, Ruderfer DM, Gresham D, Dolinski K, Botstein D, Kruglyak L. Genome-wide analysis of nucleotide-level variation in commonly used Saccharomyces cerevisiae strains. Plos One. 2: e322. PMID 17389913 DOI: 10.1371/journal.pone.0000322  1
2007 Nash R, Weng S, Hitz B, Balakrishnan R, Christie KR, Costanzo MC, Dwight SS, Engel SR, Fisk DG, Hirschman JE, Hong EL, Livstone MS, Oughtred R, Park J, Skrzypek M, ... ... Botstein D, et al. Expanded protein information at SGD: new pages and proteome browser. Nucleic Acids Research. 35: D468-71. PMID 17142221 DOI: 10.1093/nar/gkl931  1
2006 Pelham RJ, Rodgers L, Hall I, Lucito R, Nguyen KC, Navin N, Hicks J, Mu D, Powers S, Wigler M, Botstein D. Identification of alterations in DNA copy number in host stromal cells during tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 103: 19848-53. PMID 17167050 DOI: 10.1073/pnas.0609635104  1
2006 Brauer MJ, Yuan J, Bennett BD, Lu W, Kimball E, Botstein D, Rabinowitz JD. Conservation of the metabolomic response to starvation across two divergent microbes. Proceedings of the National Academy of Sciences of the United States of America. 103: 19302-7. PMID 17159141 DOI: 10.1073/pnas.0609508103  1
2006 Sørlie T, Perou CM, Fan C, Geisler S, Aas T, Nobel A, Anker G, Akslen LA, Botstein D, Børresen-Dale AL, Lønning PE. Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer. Molecular Cancer Therapeutics. 5: 2914-8. PMID 17121939 DOI: 10.1158/1535-7163.MCT-06-0126  1
2006 Hess DC, Lu W, Rabinowitz JD, Botstein D. Ammonium toxicity and potassium limitation in yeast. Plos Biology. 4: e351. PMID 17048990 DOI: 10.1371/journal.pbio.0040351  1
2006 Fisk DG, Ball CA, Dolinski K, Engel SR, Hong EL, Issel-Tarver L, Schwartz K, Sethuraman A, Botstein D, Cherry JM. Saccharomyces cerevisiae S288C genome annotation: a working hypothesis. Yeast (Chichester, England). 23: 857-65. PMID 17001629 DOI: 10.1002/yea.1400  1
2006 Wingreen N, Botstein D. Back to the future: education for systems-level biologists. Nature Reviews. Molecular Cell Biology. 7: 829-32. PMID 16990789 DOI: 10.1038/nrm2023  1
2006 Heck JA, Gresham D, Botstein D, Alani E. Accumulation of recessive lethal mutations in Saccharomyces cerevisiae mlh1 mismatch repair mutants is not associated with gross chromosomal rearrangements. Genetics. 174: 519-23. PMID 16816424 DOI: 10.1534/genetics.106.059311  1
2006 Reguly T, Breitkreutz A, Boucher L, Breitkreutz BJ, Hon GC, Myers CL, Parsons A, Friesen H, Oughtred R, Tong A, Stark C, Ho Y, Botstein D, Andrews B, Boone C, et al. Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae. Journal of Biology. 5: 11. PMID 16762047 DOI: 10.1186/jbiol36  1
2006 Botstein D. Willing to do the math: an interview with David Botstein. Interview by Jane Gitschier. Plos Genetics. 2: e79. PMID 16733551 DOI: 10.1371/journal.pgen.0020079  1
2006 Gresham D, Ruderfer DM, Pratt SC, Schacherer J, Dunham MJ, Botstein D, Kruglyak L. Genome-wide detection of polymorphisms at nucleotide resolution with a single DNA microarray. Science (New York, N.Y.). 311: 1932-6. PMID 16527929 DOI: 10.1126/science.1123726  1
2006 Diehn M, Bhattacharya R, Botstein D, Brown PO. Genome-scale identification of membrane-associated human mRNAs. Plos Genetics. 2: e11. PMID 16415983 DOI: 10.1371/journal.pgen.0020011  1
2006 Hirschman JE, Balakrishnan R, Christie KR, Costanzo MC, Dwight SS, Engel SR, Fisk DG, Hong EL, Livstone MS, Nash R, Park J, Oughtred R, Skrzypek M, Starr B, Theesfeld CL, ... ... Botstein D, et al. Genome Snapshot: a new resource at the Saccharomyces Genome Database (SGD) presenting an overview of the Saccharomyces cerevisiae genome. Nucleic Acids Research. 34: D442-5. PMID 16381907 DOI: 10.1093/nar/gkj117  1
2006 Ronen M, Botstein D. Transcriptional response of steady-state yeast cultures to transient perturbations in carbon source. Proceedings of the National Academy of Sciences of the United States of America. 103: 389-94. PMID 16381818 DOI: 10.1073/pnas.0509978103  1
2005 Dolinski K, Botstein D. Changing perspectives in yeast research nearly a decade after the genome sequence. Genome Research. 15: 1611-9. PMID 16339358 DOI: 10.1101/gr.3727505  1
2005 Liang Y, Diehn M, Watson N, Bollen AW, Aldape KD, Nicholas MK, Lamborn KR, Berger MS, Botstein D, Brown PO, Israel MA. Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme. Proceedings of the National Academy of Sciences of the United States of America. 102: 5814-9. PMID 15827123 DOI: 10.1073/pnas.0402870102  1
2005 Shyamsundar R, Kim YH, Higgins JP, Montgomery K, Jorden M, Sethuraman A, van de Rijn M, Botstein D, Brown PO, Pollack JR. A DNA microarray survey of gene expression in normal human tissues. Genome Biology. 6: R22. PMID 15774023 DOI: 10.1186/gb-2005-6-3-r22  1
2005 Brauer MJ, Saldanha AJ, Dolinski K, Botstein D. Homeostatic adjustment and metabolic remodeling in glucose-limited yeast cultures. Molecular Biology of the Cell. 16: 2503-17. PMID 15758028 DOI: 10.1091/mbc.E04-11-0968  1
2005 Wang W, Cherry JM, Nochomovitz Y, Jolly E, Botstein D, Li H. Inference of combinatorial regulation in yeast transcriptional networks: a case study of sporulation. Proceedings of the National Academy of Sciences of the United States of America. 102: 1998-2003. PMID 15684073 DOI: 10.1073/pnas.0405537102  1
2005 Balakrishnan R, Christie KR, Costanzo MC, Dolinski K, Dwight SS, Engel SR, Fisk DG, Hirschman JE, Hong EL, Nash R, Oughtred R, Skrzypek M, Theesfeld CL, Binkley G, Dong Q, ... ... Botstein D, et al. Fungal BLAST and Model Organism BLASTP Best Hits: new comparison resources at the Saccharomyces Genome Database (SGD). Nucleic Acids Research. 33: D374-7. PMID 15608219 DOI: 10.1093/nar/gki023  1
2004 Rees CA, Demeter J, Matese JC, Botstein D, Sherlock G. GeneXplorer: an interactive web application for microarray data visualization and analysis. Bmc Bioinformatics. 5: 141. PMID 15458579 DOI: 10.1186/1471-2105-5-141  1
2004 Shapira M, Segal E, Botstein D. Disruption of yeast forkhead-associated cell cycle transcription by oxidative stress. Molecular Biology of the Cell. 15: 5659-69. PMID 15371544 DOI: 10.1091/mbc.E04-04-0340  1
2004 Tu IP, Schaner M, Diehn M, Sikic BI, Brown PO, Botstein D, Fero MJ. A method for detecting and correcting feature misidentification on expression microarrays. Bmc Genomics. 5: 64. PMID 15357875 DOI: 10.1186/1471-2164-5-64  1
2004 Boyle EI, Weng S, Gollub J, Jin H, Botstein D, Cherry JM, Sherlock G. GO::TermFinder--open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes. Bioinformatics (Oxford, England). 20: 3710-5. PMID 15297299 DOI: 10.1093/bioinformatics/bth456  1
2004 Saldanha AJ, Brauer MJ, Botstein D. Nutritional homeostasis in batch and steady-state culture of yeast. Molecular Biology of the Cell. 15: 4089-104. PMID 15240820 DOI: 10.1091/mbc.E04-04-0306  1
2004 Dwight SS, Balakrishnan R, Christie KR, Costanzo MC, Dolinski K, Engel SR, Feierbach B, Fisk DG, Hirschman J, Hong EL, Issel-Tarver L, Nash RS, Sethuraman A, Starr B, Theesfeld CL, ... ... Botstein D, et al. Saccharomyces genome database: underlying principles and organisation. Briefings in Bioinformatics. 5: 9-22. PMID 15153302  1
2004 Lossos IS, Czerwinski DK, Alizadeh AA, Wechser MA, Tibshirani R, Botstein D, Levy R. Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes. The New England Journal of Medicine. 350: 1828-37. PMID 15115829 DOI: 10.1056/NEJMoa032520  1
2004 Novoradovskaya N, Whitfield ML, Basehore LS, Novoradovsky A, Pesich R, Usary J, Karaca M, Wong WK, Aprelikova O, Fero M, Perou CM, Botstein D, Braman J. Universal Reference RNA as a standard for microarray experiments. Bmc Genomics. 5: 20. PMID 15113400 DOI: 10.1186/1471-2164-5-20  1
2004 Zhao H, Langerød A, Ji Y, Nowels KW, Nesland JM, Tibshirani R, Bukholm IK, Kåresen R, Botstein D, Børresen-Dale AL, Jeffrey SS. Different gene expression patterns in invasive lobular and ductal carcinomas of the breast. Molecular Biology of the Cell. 15: 2523-36. PMID 15034139 DOI: 10.1091/mbc.E03-11-0786  1
2004 Botstein D. Ira Herskowitz: 1946-2003. Genetics. 166: 653-60. PMID 15020456  1
2004 Murray JI, Whitfield ML, Trinklein ND, Myers RM, Brown PO, Botstein D. Diverse and specific gene expression responses to stresses in cultured human cells. Molecular Biology of the Cell. 15: 2361-74. PMID 15004229 DOI: 10.1091/mbc.E03-11-0799  1
2004 Bialek W, Botstein D. Introductory science and mathematics education for 21st-Century biologists. Science (New York, N.Y.). 303: 788-90. PMID 14764865 DOI: 10.1126/science.1095480  1
2004 Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, Montgomery K, Chi JT, van de Rijn M, Botstein D, Brown PO. Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds. Plos Biology. 2: E7. PMID 14737219 DOI: 10.1371/journal.pbio.0020007  1
2004 Lapointe J, Li C, Higgins JP, van de Rijn M, Bair E, Montgomery K, Ferrari M, Egevad L, Rayford W, Bergerheim U, Ekman P, DeMarzo AM, Tibshirani R, Botstein D, Brown PO, et al. Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 101: 811-6. PMID 14711987 DOI: 10.1073/pnas.0304146101  1
2004 Christie KR, Weng S, Balakrishnan R, Costanzo MC, Dolinski K, Dwight SS, Engel SR, Feierbach B, Fisk DG, Hirschman JE, Hong EL, Issel-Tarver L, Nash R, Sethuraman A, Starr B, ... ... Botstein D, et al. Saccharomyces Genome Database (SGD) provides tools to identify and analyze sequences from Saccharomyces cerevisiae and related sequences from other organisms. Nucleic Acids Research. 32: D311-4. PMID 14681421 DOI: 10.1093/nar/gkh033  1
2004 Harris MA, Clark J, Ireland A, Lomax J, Ashburner M, Foulger R, Eilbeck K, Lewis S, Marshall B, Mungall C, Richter J, Rubin GM, Blake JA, Bult C, Dolan M, ... ... Botstein D, et al. The Gene Ontology (GO) database and informatics resource. Nucleic Acids Research. 32: D258-61. PMID 14681407 DOI: 10.1093/nar/gkh036  0.56
2004 Shakoury-Elizeh M, Tiedeman J, Rashford J, Ferea T, Demeter J, Garcia E, Rolfes R, Brown PO, Botstein D, Philpott CC. Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae. Molecular Biology of the Cell. 15: 1233-43. PMID 14668481 DOI: 10.1091/mbc.E03-09-0642  1
2004 Trinklein ND, Murray JI, Hartman SJ, Botstein D, Myers RM. The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response. Molecular Biology of the Cell. 15: 1254-61. PMID 14668476 DOI: 10.1091/mbc.E03-10-0738  1
2004 Zhao H, Whitfield ML, Xu T, Botstein D, Brooks JD. Diverse effects of methylseleninic acid on the transcriptional program of human prostate cancer cells. Molecular Biology of the Cell. 15: 506-19. PMID 14617803 DOI: 10.1091/mbc.E03-07-0501  1
2004 Alter O, Golub GH, Brown PO, Botstein D. Integrative data-driven mathematical models predict novel genome-scale correlation between DNA replication initiation and RNA transcription during the cell cycle in yeast Aiche Annual Meeting, Conference Proceedings. 1007-1008.  1
2004 Alter O, Golub GH, Brown PO, Botstein D. Integrative data-driven mathematical models predict novel genomescale correlation between DNA replication initiation and RNA transcription during the cell cycle in yeast Aiche Annual Meeting, Conference Proceedings. 8303-8304.  1
2004 Harris MA, Clark J, Ireland A, Lomax J, Ashburner M, Foulger R, Eilbeck K, Lewis S, Marshall B, Mungall C, Richter J, Rubin GM, Blake JA, Bult C, Dolan M, ... ... Botstein D, et al. The Gene Oncology (GO) database and informatics resource Nucleic Acids Research. 32: D258-D261.  1
2003 Botstein D. Genomic perspective and cancer. Cold Spring Harbor Symposia On Quantitative Biology. 68: 417-24. PMID 15338644  1
2003 Linn SC, West RB, Pollack JR, Zhu S, Hernandez-Boussard T, Nielsen TO, Rubin BP, Patel R, Goldblum JR, Siegmund D, Botstein D, Brown PO, Gilks CB, van de Rijn M. Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans. The American Journal of Pathology. 163: 2383-95. PMID 14633610 DOI: 10.1016/S0002-9440(10)63593-6  1
2003 Roose JP, Diehn M, Tomlinson MG, Lin J, Alizadeh AA, Botstein D, Brown PO, Weiss A. T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression. Plos Biology. 1: E53. PMID 14624253 DOI: 10.1371/journal.pbio.0000053  1
2003 Smith KS, Chanda SK, Lingbeek M, Ross DT, Botstein D, van Lohuizen M, Cleary ML. Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1. Molecular Cell. 12: 393-400. PMID 14536079 DOI: 10.1016/S1097-2765(03)00277-6  1
2003 Whitfield ML, Finlay DR, Murray JI, Troyanskaya OG, Chi JT, Pergamenschikov A, McCalmont TH, Brown PO, Botstein D, Connolly MK. Systemic and cell type-specific gene expression patterns in scleroderma skin. Proceedings of the National Academy of Sciences of the United States of America. 100: 12319-24. PMID 14530402 DOI: 10.1073/pnas.1635114100  1
2003 Nielsen TO, Hsu FD, O'Connell JX, Gilks CB, Sorensen PH, Linn S, West RB, Liu CL, Botstein D, Brown PO, van de Rijn M. Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology. The American Journal of Pathology. 163: 1449-56. PMID 14507652 DOI: 10.1016/S0002-9440(10)63502-X  1
2003 Chi JT, Chang HY, Haraldsen G, Jahnsen FL, Troyanskaya OG, Chang DS, Wang Z, Rockson SG, van de Rijn M, Botstein D, Brown PO. Endothelial cell diversity revealed by global expression profiling. Proceedings of the National Academy of Sciences of the United States of America. 100: 10623-8. PMID 12963823 DOI: 10.1073/pnas.1434429100  1
2003 Schaner ME, Ross DT, Ciaravino G, Sorlie T, Troyanskaya O, Diehn M, Wang YC, Duran GE, Sikic TL, Caldeira S, Skomedal H, Tu IP, Hernandez-Boussard T, Johnson SW, O'Dwyer PJ, ... ... Botstein D, et al. Gene expression patterns in ovarian carcinomas. Molecular Biology of the Cell. 14: 4376-86. PMID 12960427 DOI: 10.1091/mbc.E03-05-0279  1
2003 Chen X, Leung SY, Yuen ST, Chu KM, Ji J, Li R, Chan AS, Law S, Troyanskaya OG, Wong J, So S, Botstein D, Brown PO. Variation in gene expression patterns in human gastric cancers. Molecular Biology of the Cell. 14: 3208-15. PMID 12925757 DOI: 10.1091/mbc.E02-12-0833  1
2003 Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, Demeter J, Perou CM, Lønning PE, Brown PO, Børresen-Dale AL, ... Botstein D, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proceedings of the National Academy of Sciences of the United States of America. 100: 8418-23. PMID 12829800 DOI: 10.1073/pnas.0932692100  1
2003 Troyanskaya OG, Dolinski K, Owen AB, Altman RB, Botstein D. A Bayesian framework for combining heterogeneous data sources for gene function prediction (in Saccharomyces cerevisiae). Proceedings of the National Academy of Sciences of the United States of America. 100: 8348-53. PMID 12826619 DOI: 10.1073/pnas.0832373100  1
2003 Segal E, Shapira M, Regev A, Pe'er D, Botstein D, Koller D, Friedman N. Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data. Nature Genetics. 34: 166-76. PMID 12740579 DOI: 10.1038/ng1165  1
2003 McInnis MG, Lan TH, Willour VL, McMahon FJ, Simpson SG, Addington AM, MacKinnon DF, Potash JB, Mahoney AT, Chellis J, Huo Y, Swift-Scanlan T, Chen H, Koskela R, Stine OC, ... ... Botstein D, et al. Genome-wide scan of bipolar disorder in 65 pedigrees: supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12. Molecular Psychiatry. 8: 288-98. PMID 12660801 DOI: 10.1038/sj.mp.4001277  1
2003 Alter O, Brown PO, Botstein D. Generalized singular value decomposition for comparative analysis of genome-scale expression data sets of two different organisms. Proceedings of the National Academy of Sciences of the United States of America. 100: 3351-6. PMID 12631705 DOI: 10.1073/pnas.0530258100  1
2003 Uhlmann WR, Bennett R, Botkin JR, Botstein D, Boughman JA, Chakravarti A, Clayton EW, Kahn J, Koenig B, Murray TH, Olson MV, Rowley J, Terry S, Valle D. Planning the genome institute's future. Science (New York, N.Y.). 299: 1515; author reply 1. PMID 12624247 DOI: 10.1126/science.299.5612.1515b  1
2003 Botstein D, Risch N. Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nature Genetics. 33: 228-37. PMID 12610532 DOI: 10.1038/ng1090  1
2003 Bohen SP, Troyanskaya OG, Alter O, Warnke R, Botstein D, Brown PO, Levy R. Variation in gene expression patterns in follicular lymphoma and the response to rituximab. Proceedings of the National Academy of Sciences of the United States of America. 100: 1926-30. PMID 12571354 DOI: 10.1073/pnas.0437875100  1
2003 Ranade K, Hinds D, Hsiung CA, Chuang LM, Chang MS, Chen YT, Pesich R, Hebert J, Chen YD, Dzau V, Olshen R, Curb D, Botstein D, Cox DR, Risch N. A genome scan for hypertension susceptibility loci in populations of Chinese and Japanese origins. American Journal of Hypertension. 16: 158-62. PMID 12559686 DOI: 10.1016/S0895-7061(02)03245-4  1
2003 Diehn M, Sherlock G, Binkley G, Jin H, Matese JC, Hernandez-Boussard T, Rees CA, Cherry JM, Botstein D, Brown PO, Alizadeh AA. SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression data. Nucleic Acids Research. 31: 219-23. PMID 12519986 DOI: 10.1093/nar/gkg014  1
2003 Weng S, Dong Q, Balakrishnan R, Christie K, Costanzo M, Dolinski K, Dwight SS, Engel S, Fisk DG, Hong E, Issel-Tarver L, Sethuraman A, Theesfeld C, Andrada R, Binkley G, ... ... Botstein D, et al. Saccharomyces Genome Database (SGD) provides biochemical and structural information for budding yeast proteins. Nucleic Acids Research. 31: 216-8. PMID 12519985 DOI: 10.1093/nar/gkg054  1
2003 Gollub J, Ball CA, Binkley G, Demeter J, Finkelstein DB, Hebert JM, Hernandez-Boussard T, Jin H, Kaloper M, Matese JC, Schroeder M, Brown PO, Botstein D, Sherlock G. The Stanford Microarray Database: data access and quality assessment tools. Nucleic Acids Research. 31: 94-6. PMID 12519956 DOI: 10.1093/nar/gkg078  1
2002 Jeffrey SS, Fero MJ, Børresen-Dale AL, Botstein D. Expression array technology in the diagnosis and treatment of breast cancer. Molecular Interventions. 2: 101-9. PMID 14993355 DOI: 10.1124/mi.2.2.101  1
2002 Wang W, Cherry JM, Botstein D, Li H. A systematic approach to reconstructing transcription networks in Saccharomycescerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 99: 16893-8. PMID 12482955 DOI: 10.1073/pnas.252638199  1
2002 Gilman AG, Simon MI, Bourne HR, Harris BA, Long R, Ross EM, Stull JT, Taussig R, Bourne HR, Arkin AP, Cobb MH, Cyster JG, Devreotes PN, Ferrell JE, Fruman D, ... ... Botstein D, et al. Overview of the Alliance for Cellular Signaling. Nature. 420: 703-6. PMID 12478301 DOI: 10.1038/nature01304  0.44
2002 van de Rijn M, Perou CM, Tibshirani R, Haas P, Kallioniemi O, Kononen J, Torhorst J, Sauter G, Zuber M, Köchli OR, Mross F, Dieterich H, Seitz R, Ross D, Botstein D, et al. Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome. The American Journal of Pathology. 161: 1991-6. PMID 12466114 DOI: 10.1016/S0002-9440(10)64476-8  1
2002 Leung SY, Chen X, Chu KM, Yuen ST, Mathy J, Ji J, Chan AS, Li R, Law S, Troyanskaya OG, Tu IP, Wong J, So S, Botstein D, Brown PO. Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis. Proceedings of the National Academy of Sciences of the United States of America. 99: 16203-8. PMID 12456890 DOI: 10.1073/pnas.212646299  1
2002 Dunham MJ, Badrane H, Ferea T, Adams J, Brown PO, Rosenzweig F, Botstein D. Characteristic genome rearrangements in experimental evolution of Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 99: 16144-9. PMID 12446845 DOI: 10.1073/pnas.242624799  1
2002 Troyanskaya OG, Garber ME, Brown PO, Botstein D, Altman RB. Nonparametric methods for identifying differentially expressed genes in microarray data. Bioinformatics (Oxford, England). 18: 1454-61. PMID 12424116  1
2002 Chang HY, Chi JT, Dudoit S, Bondre C, van de Rijn M, Botstein D, Brown PO. Diversity, topographic differentiation, and positional memory in human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 99: 12877-82. PMID 12297622 DOI: 10.1073/pnas.162488599  1
2002 Pollack JR, Sørlie T, Perou CM, Rees CA, Jeffrey SS, Lonning PE, Tibshirani R, Botstein D, Børresen-Dale AL, Brown PO. Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors. Proceedings of the National Academy of Sciences of the United States of America. 99: 12963-8. PMID 12297621 DOI: 10.1073/pnas.162471999  1
2002 Trotter EW, Kao CM, Berenfeld L, Botstein D, Petsko GA, Gray JV. Misfolded proteins are competent to mediate a subset of the responses to heat shock in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 277: 44817-25. PMID 12239211 DOI: 10.1074/jbc.M204686200  1
2002 Diehn M, Alizadeh AA, Rando OJ, Liu CL, Stankunas K, Botstein D, Crabtree GR, Brown PO. Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation. Proceedings of the National Academy of Sciences of the United States of America. 99: 11796-801. PMID 12195013 DOI: 10.1073/pnas.092284399  1
2002 Sayama K, Diehn M, Matsuda K, Lunderius C, Tsai M, Tam SY, Botstein D, Brown PO, Galli SJ. Transcriptional response of human mast cells stimulated via the Fc(epsilon)RI and identification of mast cells as a source of IL-11. Bmc Immunology. 3: 5. PMID 12079505  1
2002 Lossos IS, Alizadeh AA, Diehn M, Warnke R, Thorstenson Y, Oefner PJ, Brown PO, Botstein D, Levy R. Transformation of follicular lymphoma to diffuse large-cell lymphoma: alternative patterns with increased or decreased expression of c-myc and its regulated genes. Proceedings of the National Academy of Sciences of the United States of America. 99: 8886-91. PMID 12077300 DOI: 10.1073/pnas.132253599  1
2002 Mulholland J, Botstein D. Immunoelectron microscopy of aldehyde-fixed yeast cells. Methods in Enzymology. 351: 50-81. PMID 12073367 DOI: 10.1016/S0076-6879(02)51841-3  1
2002 Issel-Tarver L, Christie KR, Dolinski K, Andrada R, Balakrishnan R, Ball CA, Binkley G, Dong S, Dwight SS, Fisk DG, Harris M, Schroeder M, Sethuraman A, Tse K, Weng S, ... Botstein D, et al. Saccharomyces Genome Database. Methods in Enzymology. 350: 329-46. PMID 12073322 DOI: 10.1016/S0076-6879(02)50972-1  1
2002 Pollack JR, Van de Rijn M, Botstein D. Challenges in developing a molecular characterization of cancer. Seminars in Oncology. 29: 280-5. PMID 12063681 DOI: 10.1053/sonc.2002.32903  1
2002 Whitfield ML, Sherlock G, Saldanha AJ, Murray JI, Ball CA, Alexander KE, Matese JC, Perou CM, Hurt MM, Brown PO, Botstein D. Identification of genes periodically expressed in the human cell cycle and their expression in tumors. Molecular Biology of the Cell. 13: 1977-2000. PMID 12058064 DOI: 10.1091/mbc.02-02-0030.  1
2002 Chen X, Cheung ST, So S, Fan ST, Barry C, Higgins J, Lai KM, Ji J, Dudoit S, Ng IO, Van De Rijn M, Botstein D, Brown PO. Gene expression patterns in human liver cancers. Molecular Biology of the Cell. 13: 1929-39. PMID 12058060 DOI: 10.1091/mbc.02-02-0023.  1
2002 Yoshimoto H, Saltsman K, Gasch AP, Li HX, Ogawa N, Botstein D, Brown PO, Cyert MS. Genome-wide analysis of gene expression regulated by the calcineurin/Crz1p signaling pathway in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 277: 31079-88. PMID 12058033 DOI: 10.1074/jbc.M202718200  1
2002 Click ES, Stearns T, Botstein D. Systematic structure-function analysis of the small GTPase Arf1 in yeast. Molecular Biology of the Cell. 13: 1652-64. PMID 12006660 DOI: 10.1091/mbc.02-01-0007  1
2002 Nielsen TO, West RB, Linn SC, Alter O, Knowling MA, O'Connell JX, Zhu S, Fero M, Sherlock G, Pollack JR, Brown PO, Botstein D, van de Rijn M. Molecular characterisation of soft tissue tumours: a gene expression study. Lancet (London, England). 359: 1301-7. PMID 11965276 DOI: 10.1016/S0140-6736(02)08270-3  1
2002 Ranade K, Jorgenson E, Sheu WH, Pei D, Hsiung CA, Chiang FT, Chen YD, Pratt R, Olshen RA, Curb D, Cox DR, Botstein D, Risch N. A polymorphism in the beta1 adrenergic receptor is associated with resting heart rate. American Journal of Human Genetics. 70: 935-42. PMID 11854867 DOI: 10.1086/339621  1
2002 Boldrick JC, Alizadeh AA, Diehn M, Dudoit S, Liu CL, Belcher CE, Botstein D, Staudt LM, Brown PO, Relman DA. Stereotyped and specific gene expression programs in human innate immune responses to bacteria. Proceedings of the National Academy of Sciences of the United States of America. 99: 972-7. PMID 11805339 DOI: 10.1073/pnas.231625398  1
2002 Dwight SS, Harris MA, Dolinski K, Ball CA, Binkley G, Christie KR, Fisk DG, Issel-Tarver L, Schroeder M, Sherlock G, Sethuraman A, Weng S, Botstein D, Cherry JM. Saccharomyces Genome Database (SGD) provides secondary gene annotation using the Gene Ontology (GO). Nucleic Acids Research. 30: 69-72. PMID 11752257  1
2002 Sayama K, Diehn M, Matsuda K, Lunderius C, Tsai M, Tam SY, Botstein D, Brown PO, Galli SJ. Transcriptional response of human mast cells stimulated via the Fcε RI and identification of mast cells as a source of IL-11 Bmc Immunology. 3. DOI: 10.1186/1471-2172-3-5  1
2002 Tibshirani R, Hastie T, Narasimhan B, Eisen M, Sherlock G, Brown P, Botstein D. Exploratory screening of genes and clusters from microarray experiments Statistica Sinica. 12: 47-59.  1
2001 Ranade K, Shue WHH, Hung YJ, Hsuing CA, Chiang FT, Pesich R, Hebert J, Olivier M, Chen YDI, Pratt R, Olshen R, Curb D, Botstein D, Risch N, Cox DR. The glycine allele of a glycine/arginine polymorphism in the β2-adrenergic receptor gene is associated with essential hypertension in a population of Chinese origin American Journal of Hypertension. 14: 1196-1200. PMID 11775126 DOI: 10.1016/S0895-7061(01)02213-0  1
2001 Anders KR, Botstein D. Dominant-lethal α-tubulin mutants defective in microtubule depolymerization in yeast Molecular Biology of the Cell. 12: 3973-3986. PMID 11739794  1
2001 Rosenwald A, Alizadeh AA, Widhopf G, Simon R, Davis RE, Yu X, Yang L, Pickeral OK, Rassenti LZ, Powell J, Botstein D, Byrd JC, Grever MR, Cheson BD, Chiorazzi N, et al. Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. The Journal of Experimental Medicine. 194: 1639-47. PMID 11733578 DOI: 10.1084/jem.194.11.1639  1
2001 Garber ME, Troyanskaya OG, Schluens K, Petersen S, Thaesler Z, Pacyna-Gengelbach M, van de Rijn M, Rosen GD, Perou CM, Whyte RI, Altman RB, Brown PO, Botstein D, Petersen I. Diversity of gene expression in adenocarcinoma of the lung. Proceedings of the National Academy of Sciences of the United States of America. 98: 13784-9. PMID 11707590 DOI: 10.1073/pnas.241500798  1
2001 Ranade K, Wu KD, Risch N, Olivier M, Pei D, Hsiao CF, Chuang LM, Ho LT, Jorgenson E, Pesich R, Chen YD, Dzau V, Lin A, Olshen RA, Curb D, ... ... Botstein D, et al. Genetic variation in aldosterone synthase predicts plasma glucose levels. Proceedings of the National Academy of Sciences of the United States of America. 98: 13219-24. PMID 11687612 DOI: 10.1073/pnas.221467098  1
2001 Protchenko O, Ferea T, Rashford J, Tiedeman J, Brown PO, Botstein D, Philpott CC. Three cell wall mannoproteins facilitate the uptake of iron in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 276: 49244-50. PMID 11673473 DOI: 10.1074/jbc.M109220200  1
2001 Gasch AP, Huang M, Metzner S, Botstein D, Elledge SJ, Brown PO. Genomic expression responses to DNA-damaging agents and the regulatory role of the yeast ATR homolog Mec1p. Molecular Biology of the Cell. 12: 2987-3003. PMID 11598186  1
2001 Ranade K, Wu KD, Hwu CM, Ting CT, Pei D, Pesich R, Hebert J, Chen YDI, Pratt R, Olshen R, Masaki K, Risch N, Cox DR, Botstein D. Genetic variation in the human urea transporter-2 is associated with variation in blood pressure Human Molecular Genetics. 10: 2157-2164. PMID 11590132  1
2001 Lønning PE, Sørlie T, Perou CM, Brown PO, Botstein D, Børresen-Dale AL. Microarrays in primary breast cancer--lessons from chemotherapy studies. Endocrine-Related Cancer. 8: 259-63. PMID 11566617 DOI: 10.1677/erc.0.0080259  1
2001 Sørlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, Hastie T, Eisen MB, van de Rijn M, Jeffrey SS, Thorsen T, Quist H, Matese JC, Brown PO, Botstein D, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proceedings of the National Academy of Sciences of the United States of America. 98: 10869-74. PMID 11553815 DOI: 10.1073/pnas.191367098  1
2001 Finlin BS, Gau CL, Murphy GA, Shao H, Kimel T, Seitz RS, Chiu YF, Botstein D, Brown PO, Der CJ, Tamanoi F, Andres DA, Perou CM. RERG is a novel ras-related, estrogen-regulated and growth-inhibitory gene in breast cancer. The Journal of Biological Chemistry. 276: 42259-67. PMID 11533059 DOI: 10.1074/jbc.M105888200  1
2001 Lieb JD, Liu X, Botstein D, Brown PO. Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association. Nature Genetics. 28: 327-34. PMID 11455386 DOI: 10.1038/ng569  1
2001 Ranade K, Chang MS, Ting CT, Pei D, Hsiao CF, Olivier M, Pesich R, Hebert J, Chen YDI, Dzau VJ, Curb D, Olshen R, Risch N, Cox DR, Botstein D. High-throughput genotyping with single nucleotide polymorphisms Genome Research. 11: 1262-1268. PMID 11435409 DOI: 10.1101/gr.GR-1578R  1
2001 Troyanskaya O, Cantor M, Sherlock G, Brown P, Hastie T, Tibshirani R, Botstein D, Altman RB. Missing value estimation methods for DNA microarrays Bioinformatics. 17: 520-525. PMID 11395428  1
2001 Iyer VR, Horak CE, Scafe CS, Botstein D, Snyder M, Brown PO. Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF. Nature. 409: 533-8. PMID 11206552 DOI: 10.1038/35054095  1
2001 Hastie T, Tibshirani R, Botstein D, Brown P. Supervised harvesting of expression trees Genome Biology. 2: RESEARCH0003. PMID 11178280  1
2001 Carmel-Harel O, Stearman R, Gasch AP, Botstein D, Brown PO, Storz G. Role of thioredoxin reductase in the Yap1p-dependent response to oxidative stress in Saccharomyces cerevisiae. Molecular Microbiology. 39: 595-605. PMID 11169101 DOI: 10.1046/j.1365-2958.2001.02255.x  1
2001 Sherlock G, Hernandez-Boussard T, Kasarskis A, Binkley G, Matese JC, Dwight SS, Kaloper M, Weng S, Jin H, Ball CA, Eisen MB, Spellman PT, Brown PO, Botstein D, Cherry JM. The Stanford Microarray Database. Nucleic Acids Research. 29: 152-5. PMID 11125075  1
2001 Ball CA, Jin H, Sherlock G, Weng S, Matese JC, Andrada R, Binkley G, Dolinski K, Dwight SS, Harris MA, Issel-Tarver L, Schroeder M, Botstein D, Cherry JM. Saccharomyces genome database provides tools to survey gene expression and functional analysis data Nucleic Acids Research. 29: 80-81. PMID 11125055  1
2001 Alter O, Brown PO, Botstein D. Processing and modeling genome-wide expression data using singular value decomposition Proceedings of Spie - the International Society For Optical Engineering. 4266: 171-186. DOI: 10.1117/12.427986  1
2000 Lee SE, Pellicioli A, Demeter J, Vaze MP, Gasch AP, Malkova A, Brown PO, Botstein D, Stearns T, Foiani M, Haber JE. Arrest, adaptation, and recovery following a chromosome double-strand break in Saccharomyces cerevisiae. Cold Spring Harbor Symposia On Quantitative Biology. 65: 303-14. PMID 12760044  1
2000 Hastie T, Tibshirani R, Eisen MB, Alizadeh A, Levy R, Staudt L, Chan WC, Botstein D, Brown P. 'Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns. Genome Biology. 1: RESEARCH0003. PMID 11178228 DOI: 10.1186/gb-2000-1-2-research0003  1
2000 Gasch AP, Spellman PT, Kao CM, Carmel-Harel O, Eisen MB, Storz G, Botstein D, Brown PO. Genomic expression programs in the response of yeast cells to environmental changes. Molecular Biology of the Cell. 11: 4241-57. PMID 11102521  1
2000 Khodursky AB, Peter BJ, Cozzarelli NR, Botstein D, Brown PO, Yanofsky C. DNA microarray analysis of gene expression in response to physiological and genetic changes that affect tryptophan metabolism in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 97: 12170-5. PMID 11027315 DOI: 10.1073/pnas.220414297  1
2000 Alter O, Brown PO, Botstein D. Singular value decomposition for genome-Wide expression data processing and modeling Proceedings of the National Academy of Sciences of the United States of America. 97: 10101-10106. PMID 10963673  1
2000 Perou CM, Sørlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lønning PE, ... ... Botstein D, et al. Molecular portraits of human breast tumours. Nature. 406: 747-52. PMID 10963602 DOI: 10.1038/35021093  1
2000 Lossos IS, Alizadeh AA, Eisen MB, Chan WC, Brown PO, Botstein D, Staudt LM, Levy R. Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas. Proceedings of the National Academy of Sciences of the United States of America. 97: 10209-13. PMID 10954754 DOI: 10.1073/pnas.180316097  1
2000 Khodursky AB, Peter BJ, Schmid MB, DeRisi J, Botstein D, Brown PO, Cozzarelli NR. Analysis of topoisomerase function in bacterial replication fork movement: use of DNA microarrays. Proceedings of the National Academy of Sciences of the United States of America. 97: 9419-24. PMID 10944214  1
2000 Ranade K, Hsuing AC, Wu KD, Chang MS, Chen YT, Hebert J, Chen YDI, Olshen R, Curb D, Dzau V, Botstein D, Cox D, Risch N. Lack of evidence for an association between α-adducin and blood pressure regulation in Asian populations American Journal of Hypertension. 13: 704-709. PMID 10912757 DOI: 10.1016/S0895-7061(00)00238-7  1
2000 Zhu G, Spellman PT, Volpe T, Brown PO, Botstein D, Davis TN, Futcher B. Two yeast forkhead genes regulate the cell cycle and pseudohyphal growth. Nature. 406: 90-4. PMID 10894548 DOI: 10.1038/35017581  1
2000 Lyons TJ, Gasch AP, Gaither LA, Botstein D, Brown PO, Eide DJ. Genome-wide characterization of the Zap1p zinc-responsive regulon in yeast. Proceedings of the National Academy of Sciences of the United States of America. 97: 7957-62. PMID 10884426 DOI: 10.1073/pnas.97.14.7957  1
2000 Diehn M, Eisen MB, Botstein D, Brown PO. Large-scale identification of secreted and membrane-associated gene products using DNA microarrays. Nature Genetics. 25: 58-62. PMID 10802657 DOI: 10.1038/75603  1
2000 Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, Davis AP, Dolinski K, Dwight SS, Eppig JT, Harris MA, Hill DP, Issel-Tarver L, Kasarskis A, Lewis S, et al. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nature Genetics. 25: 25-9. PMID 10802651 DOI: 10.1038/75556  1
2000 Richards KL, Anders KR, Nogales E, Schwartz K, Downing KH, Botstein D. Structure-function relationships in yeast tubulins. Molecular Biology of the Cell. 11: 1887-903. PMID 10793159  1
2000 Yun CW, Ferea T, Rashford J, Ardon O, Brown PO, Botstein D, Kaplan J, Philpott CC. Desferrioxamine-mediated iron uptake in Saccharomyces cerevisiae. Evidence for two pathways of iron uptake Journal of Biological Chemistry. 275: 10709-10715. PMID 10744769 DOI: 10.1074/jbc.275.14.10709  1
2000 Scherf U, Ross DT, Waltham M, Smith LH, Lee JK, Tanabe L, Kohn KW, Reinhold WC, Myers TG, Andrews DT, Scudiero DA, Eisen MB, Sausville EA, Pommier Y, Botstein D, et al. A gene expression database for the molecular pharmacology of cancer. Nature Genetics. 24: 236-44. PMID 10700175 DOI: 10.1038/73439  1
2000 Ross DT, Scherf U, Eisen MB, Perou CM, Rees C, Spellman P, Iyer V, Jeffrey SS, Van de Rijn M, Waltham M, Pergamenschikov A, Lee JC, Lashkari D, Shalon D, Myers TG, ... ... Botstein D, et al. Systematic variation in gene expression patterns in human cancer cell lines. Nature Genetics. 24: 227-35. PMID 10700174 DOI: 10.1038/73432  1
2000 Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A, Boldrick JC, Sabet H, Tran T, Yu X, Powell JI, Yang L, Marti GE, Moore T, Hudson J, ... ... Botstein D, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature. 403: 503-11. PMID 10676951 DOI: 10.1038/35000501  1
2000 Friddle C, Koskela R, Ranade K, Hebert J, Cargill M, Clark CD, McInnis M, Simpson S, McMahon F, Stine OC, Meyers D, Xu J, MacKinnon D, Swift-Scanlan T, Jamison K, ... ... Botstein D, et al. Full-genome scan for linkage in 50 families segregating the bipolar affective disease phenotype. American Journal of Human Genetics. 66: 205-15. PMID 10631152 DOI: 10.1086/302697  1
2000 Ball CA, Dolinski K, Dwight SS, Harris MA, Issel-Tarver L, Kasarskis A, Scafe CR, Sherlock G, Binkley G, Jin H, Kaloper M, Orr SD, Schroeder M, Weng S, Zhu Y, ... Botstein D, et al. Integrating functional genomic information into the Saccharomyces Genome Database Nucleic Acids Research. 28: 77-80. PMID 10592186  1
2000 Perou CM, Brown PO, Botstein D. Tumor classification using gene expression patterns from DNA microarrays Trends in Ecology and Evolution. 67-76.  1
1999 Alizadeh A, Eisen M, Davis RE, Ma C, Sabet H, Tran T, Powell JI, Yang L, Marti GE, Moore DT, Hudson JR, Chan WC, Greiner T, Weisenburger D, Armitage JO, ... ... Botstein D, et al. The lymphochip: a specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes. Cold Spring Harbor Symposia On Quantitative Biology. 64: 71-8. PMID 11232339  1
1999 Pollack JR, Perou CM, Alizadeh AA, Eisen MB, Pergamenschikov A, Williams CF, Jeffrey SS, Botstein D, Brown PO. Genome-wide analysis of DNA copy-number changes using cDNA microarrays. Nature Genetics. 23: 41-6. PMID 10471496 DOI: 10.1038/12640  1
1999 Ferea TL, Botstein D, Brown PO, Rosenzweig RF. Systematic changes in gene expression patterns following adaptive evolution in yeast. Proceedings of the National Academy of Sciences of the United States of America. 96: 9721-6. PMID 10449761 DOI: 10.1073/pnas.96.17.9721  1
1999 Perou CM, Jeffrey SS, van de Rijn M, Rees CA, Eisen MB, Ross DT, Pergamenschikov A, Williams CF, Zhu SX, Lee JC, Lashkari D, Shalon D, Brown PO, Botstein D. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proceedings of the National Academy of Sciences of the United States of America. 96: 9212-7. PMID 10430922 DOI: 10.1073/pnas.96.16.9212  1
1999 Botstein D. Of genes and genomes Annals of the New York Academy of Sciences. 882: 32-41. PMID 10415884 DOI: 10.1111/j.1749-6632.1999.tb08531.x  1
1999 Mulholland J, Konopka J, Singer-Kruger B, Zerial M, Botstein D. Visualization of receptor-mediated endocytosis in yeast Molecular Biology of the Cell. 10: 799-817. PMID 10069819  1
1999 Brown PO, Botstein D. Exploring the new world of the genome with DNA microarrays Nature Genetics. 21: 33-37. PMID 9915498 DOI: 10.1038/4462  1
1999 Iyer VR, Eisen MB, Ross DT, Schuler G, Moore T, Lee JC, Trent JM, Staudt LM, Hudson J, Boguski MS, Lashkari D, Shalon D, Botstein D, Brown PO. The transcriptional program in the response of human fibroblasts to serum. Science (New York, N.Y.). 283: 83-7. PMID 9872747 DOI: 10.1126/science.283.5398.83  1
1999 Chervitz SA, Hester ET, Ball CA, Dolinski K, Dwight SS, Harris MA, Juvik G, Malekian A, Roberts S, Roe T, Scafe C, Schroeder M, Sherlock G, Weng S, Zhu Y, ... ... Botstein D, et al. Using the Saccharomyces Genome Database (SGD) for analysis of protein similarities and structure. Nucleic Acids Research. 27: 74-8. PMID 9847146 DOI: 10.1093/nar/27.1.74  1
1998 Dolinski K, Ball CA, Chervitz SA, Dwight SS, Harris MA, Roberts S, Roe T, Cherry JM, Botstein D. Expanding yeast knowledge online. Yeast (Chichester, England). 14: 1453-69. PMID 9885151 DOI: 10.1002/(SICI)1097-0061(199812)14:16<1453::AID-YEA348>3.0.CO;2-G  0.56
1998 Chervitz SA, Aravind L, Sherlock G, Ball CA, Koonin EV, Dwight SS, Harris MA, Dolinski K, Mohr S, Smith T, Weng S, Cherry JM, Botstein D. Comparison of the complete protein sets of worm and yeast: orthology and divergence. Science (New York, N.Y.). 282: 2022-8. PMID 9851918  0.56
1998 Eisen MB, Spellman PT, Brown PO, Botstein D. Cluster analysis and display of genome-wide expression patterns. Proceedings of the National Academy of Sciences of the United States of America. 95: 14863-8. PMID 9843981 DOI: 10.1073/pnas.95.25.14863  1
1998 Spellman PT, Sherlock G, Zhang MQ, Iyer VR, Anders K, Eisen MB, Brown PO, Botstein D, Futcher B. Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization. Molecular Biology of the Cell. 9: 3273-97. PMID 9843569  1
1998 Chu S, DeRisi J, Eisen M, Mulholland J, Botstein D, Brown PO, Herskowitz I. The transcriptional program of sporulation in budding yeast. Science (New York, N.Y.). 282: 699-705. PMID 9784122 DOI: 10.1126/science.282.5389.699  1
1998 Cherry JM, Adler C, Ball C, Chervitz SA, Dwight SS, Hester ET, Jia Y, Juvik G, Roe T, Schroeder M, Weng S, Botstein D. SGD: Saccharomyces Genome Database. Nucleic Acids Research. 26: 73-9. PMID 9399804 DOI: 10.1093/nar/26.1.73  1
1997 Botstein D, Chervitz SA, Cherry JM. Yeast as a model organism. Science (New York, N.Y.). 277: 1259-60. PMID 9297238  0.56
1993 Dunn B, Stearns T, Botstein D. Specificity domains distinguish the Ras-related GTPases Ypt1 and Sec4. Nature. 362: 563-5. PMID 8464499 DOI: 10.1038/362563a0  1
1991 Preuss D, Mulholland J, Kaiser CA, Orlean P, Albright C, Rose MD, Robbins PW, Botstein D. Structure of the yeast endoplasmic reticulum: localization of ER proteins using immunofluorescence and immunoelectron microscopy. Yeast (Chichester, England). 7: 891-911. PMID 1803815 DOI: 10.1002/yea.320070902  1
1990 Stearns T, Hoyt MA, Botstein D. Yeast mutants sensitive to antimicrotubule drugs define three genes that affect microtubule function. Genetics. 124: 251-62. PMID 2407611  1
1990 Kunes S, Botstein D, Fox MS. Synapsis-mediated fusion of free DNA ends forms inverted dimer plasmids in yeast. Genetics. 124: 67-80. PMID 2407606  1
1990 Hoyt MA, Stearns T, Botstein D. Chromosome instability mutants of Saccharomyces cerevisiae that are defective in microtubule-mediated processes. Molecular and Cellular Biology. 10: 223-34. PMID 2403635  1
1990 Stearns T, Ma H, Botstein D. Manipulating yeast genome using plasmid vectors. Methods in Enzymology. 185: 280-97. PMID 2199782 DOI: 10.1016/0076-6879(90)85025-J  1
1990 Kaiser CA, Botstein D. Efficiency and diversity of protein localization by random signal sequences. Molecular and Cellular Biology. 10: 3163-73. PMID 2160595  0.92
1990 Stearns T, Kahn RA, Botstein D, Hoyt MA. ADP ribosylation factor is an essential protein in Saccharomyces cerevisiae and is encoded by two genes. Molecular and Cellular Biology. 10: 6690-9. PMID 2123295  1
1990 Stearns T, Willingham MC, Botstein D, Kahn RA. ADP-ribosylation factor is functionally and physically associated with the Golgi complex. Proceedings of the National Academy of Sciences of the United States of America. 87: 1238-42. PMID 2105501  1
1989 Holm C, Stearns T, Botstein D. DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage. Molecular and Cellular Biology. 9: 159-68. PMID 2538717  1
1988 Stearns T, Botstein D. Unlinked noncomplementation: isolation of new conditional-lethal mutations in each of the tubulin genes of Saccharomyces cerevisiae. Genetics. 119: 249-60. PMID 3294100  1
1988 Botstein D, Segev N, Stearns T, Hoyt MA, Holden J, Kahn RA. Diverse biological functions of small GTP-binding proteins in yeast. Cold Spring Harbor Symposia On Quantitative Biology. 53: 629-36. PMID 3151179  1
1987 Kunes S, Ma H, Overbye K, Fox MS, Botstein D. Fine structure recombinational analysis of cloned genes using yeast transformation. Genetics. 115: 73-81. PMID 3549444  1
1987 Kaiser CA, Preuss D, Grisafi P, Botstein D. Many random sequences functionally replace the secretion signal sequence of yeast invertase. Science (New York, N.Y.). 235: 312-7. PMID 3541205  0.92
1987 Rose MD, Novick P, Thomas JH, Botstein D, Fink GR. A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector. Gene. 60: 237-43. PMID 3327750 DOI: 10.1016/0378-1119(87)90232-0  1
1987 Ma H, Kunes S, Schatz PJ, Botstein D. Plasmid construction by homologous recombination in yeast. Gene. 58: 201-16. PMID 2828185 DOI: 10.1016/0378-1119(87)90376-3  1
1986 Kaiser CA, Botstein D. Secretion-defective mutations in the signal sequence for Saccharomyces cerevisiae invertase. Molecular and Cellular Biology. 6: 2382-91. PMID 3537718  0.92
1986 Brissenden JE, Page DC, de Martinville B, Trowsdale J, Botstein D, Francke U. Regional assignments of three polymorphic DNA segments on human chromosome 15. Genetic Epidemiology. 3: 231-9. PMID 3017806 DOI: 10.1002/gepi.1370030404  0.32
1986 Vergnaud G, Page DC, Simmler MC, Brown L, Rouyer F, Noel B, Botstein D, de la Chapelle A, Weissenbach J. A deletion map of the human Y chromosome based on DNA hybridization. American Journal of Human Genetics. 38: 109-24. PMID 3004206  1
1985 Kunes S, Botstein D, Fox MS. Transformation of yeast with linearized plasmid DNA. Formation of inverted dimers and recombinant plasmid products. Journal of Molecular Biology. 184: 375-87. PMID 3900413 DOI: 10.1016/0022-2836(85)90288-8  1
1984 Kunes S, Botstein D, Fox MS. Formation of inverted dimer plasmids after transformation of yeast with linearized plasmid DNA. Cold Spring Harbor Symposia On Quantitative Biology. 49: 617-28. PMID 6397317  1
1984 Page DC, Harper ME, Love J, Botstein D. Occurrence of a transposition from the X-chromosome long arm to the Y-chromosome short arm during human evolution. Nature. 311: 119-23. PMID 6088994  0.32
1981 Winston F, Botstein D. Control of lysogenization by phage P22. II. Mutations (clyA) in the cl gene that cause increased lysogenization. Journal of Molecular Biology. 152: 233-45. PMID 7328657  1
1981 Winston F, Botstein D. Control of lysogenization by phage P22. I. The P22 cro gene. Journal of Molecular Biology. 152: 209-32. PMID 7328656  1
1979 Winston F, Botstein D, Miller JH. Characterization of amber and ochre suppressors in Salmonella typhimurium. Journal of Bacteriology. 137: 433-9. PMID 368021  1
1974 Botstein D, Herskowitz I. Properties of hybrids between Salmonella phage P22 and coliphage lambda. Nature. 251: 584-9. PMID 4608090  1
1972 Ebel-Tsipis J, Fox MS, Botstein D. Generalized transduction by bacteriophage P22 in Salmonella typhimurium. II. Mechanism of integration of transducing DNA. Journal of Molecular Biology. 71: 449-69. PMID 4564487 DOI: 10.1016/0022-2836(72)90362-2  1
1972 Ebel-Tsipis J, Botstein D, Fox MS. Generalized transduction by phage P22 in Salmonella typhimurium. I. Molecular origin of transducing DNA. Journal of Molecular Biology. 71: 433-48. PMID 4564486 DOI: 10.1016/0022-2836(72)90361-0  1
1968 Botstein D, Levine M. Synthesis and maturation of phage P22 DNA. II. Properties of temperature-sensitive phage mutants defective in DNA metabolism. Journal of Molecular Biology. 34: 643-54. PMID 4938562  0.96
1968 Botstein D, Levine M. Intermediates in the synthesis of phage P22 DNA. Cold Spring Harbor Symposia On Quantitative Biology. 33: 659-67. PMID 4892003  0.96
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