Jack E. Baldwin - Publications

Affiliations: 
1965-1967 Imperial College, London, London, England, United Kingdom 
 1967-1970 Pennsylvania State University, State College, PA, United States 
 1970-1978 Massachusetts Institute of Technology, Cambridge, MA, United States 
 1972-1972 King's College London, London, UK 
 1978-2020 University of Oxford, Oxford, United Kingdom 
Area:
Synthetic chemistry and reaction mechanisms, natural products
Website:
http://www.rsc.org/Publishing/Journals/cc/News/BaldwinInterview.asp

487 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kuan KKW, Markwell-Heys AW, Cruickshank MC, Tran DP, Adlington RM, Baldwin JE, George JH. Biomimetic synthetic studies on meroterpenoids from the marine sponge Aka coralliphaga: Divergent total syntheses of siphonodictyal B, liphagal and corallidictyals A-D. Bioorganic & Medicinal Chemistry. PMID 30992205 DOI: 10.1016/J.Bmc.2019.02.038  0.535
2018 Lee V, He J, Baldwin J. Studies towards the Synthesis of the Antibiotic Tetrodecamycin Synlett. 29: 1117-1121. DOI: 10.1055/S-0037-1609303  0.407
2017 McNeill L, Brown T, Sami M, Clifton I, Burzlaff N, Claridge T, Adlington R, Baldwin J, Rutledge PJ, Schofield C. Terminally truncated isopenicillin N synthase generates a dithioester product: evidence for a thioaldehyde intermediate and a new mode of reaction for non-heme iron oxidases. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28703303 DOI: 10.1002/Chem.201701592  0.816
2015 Tchabanenko K, Chesworth R, Parker JS, Anand NK, Russell AT, Adlington RM, Baldwin JE. Retraction notice to "Biomimetic approach to Galbulimina type I alkaloids" [Tetrahedron 61 (2005) 11649-11656] Tetrahedron. DOI: 10.1016/J.Tet.2015.12.025  0.468
2013 Clifton IJ, Ge W, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of an isopenicillin N synthase complex with an ethereal substrate analogue reveals water in the oxygen binding site Febs Letters. 587: 2705-2709. PMID 23860486 DOI: 10.1016/J.Febslet.2013.07.016  0.801
2013 Daruzzaman A, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. The Interaction of Isopenicillin N Synthase with Homologated Substrate Analogues δ-(L-α-Aminoadipoyl)-L-homocysteinyl-D-Xaa Characterised by Protein Crystallography Chembiochem. 14: 599-606. PMID 23468426 DOI: 10.1002/Cbic.201200728  0.803
2013 Daruzzaman A, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of isopenicillin N synthase with a dipeptide substrate analogue Archives of Biochemistry and Biophysics. 530: 48-53. PMID 23262315 DOI: 10.1016/J.Abb.2012.12.012  0.8
2012 Jones MW, Baldwin JE, Cowley AR, Dilworth JR, Karpov A, Smiljanic N, Thompson AL, Adlington RM. Synthesis of new bulky bis(pyrazolyl)methane carboxylate (heteroscorpionate) ligands and their complexes with iron, manganese and nickel. Dalton Transactions (Cambridge, England : 2003). 41: 14068-86. PMID 23064694 DOI: 10.1039/C2Dt31859H  0.528
2011 Clifton IJ, Ge W, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of isopenicillin N synthase with δ-(l-α- aminoadipoyl)-l-cysteinyl-d-methionine reveals thioether coordination to iron Archives of Biochemistry and Biophysics. 516: 103-107. PMID 22001738 DOI: 10.1016/J.Abb.2011.09.014  0.806
2011 Clifton IJ, Ge W, Adlington RM, Baldwin JE, Rutledge PJ. Isopenicillin N Synthase Binds δ-(L-α-Aminoadipoyl)-L-Cysteinyl-D-Thia-allo-Isoleucine through both Sulfur Atoms Chembiochem. 12: 1881-1885. PMID 21678539 DOI: 10.1002/Cbic.201100149  0.807
2010 Ge W, Clifton IJ, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. Crystallographic studies on the binding of selectively deuterated LLD- and LLL-substrate epimers by isopenicillin N synthase Biochemical and Biophysical Research Communications. 398: 659-664. PMID 20603104 DOI: 10.1016/J.Bbrc.2010.06.129  0.806
2010 George JH, Hesse MD, Baldwin JE, Adlington RM. Biomimetic synthesis of polycyclic polyprenylated acylphloroglucinol natural products isolated from hypericum papuanum Organic Letters. 12: 3532-3535. PMID 20590087 DOI: 10.1021/Ol101380A  0.486
2010 George JH, Baldwin JE, Adlington RM. Enantiospecific, biosynthetically inspired formal total synthesis of (+)-liphagal Organic Letters. 12: 2394-2397. PMID 20394432 DOI: 10.1021/Ol100756Z  0.542
2010 Lawrence AL, Adlington RM, Baldwin JE, Lee V, Kershaw JA, Thompson AL. A short biomimetic synthesis of the meroterpenoids guajadial and psidial A. Organic Letters. 12: 1676-9. PMID 20235528 DOI: 10.1021/Ol100138K  0.566
2010 Ge W, Clifton IJ, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. The crystal structure of an LLL-configured depsipeptide substrate analogue bound to isopenicillin N synthase Organic and Biomolecular Chemistry. 8: 122-127. PMID 20024142 DOI: 10.1039/B910170E  0.813
2010 George JH, McArdle M, Baldwin JE, Adlington RM. Biomimetic rearrangements of simplified labdane diterpenoids Tetrahedron. 66: 6321-6330. DOI: 10.1016/J.Tet.2010.05.052  0.559
2010 Jones MW, Adlington RM, Baldwin JE, Le Pevelen DD, Smiljanic N. New mononuclear Pd(II) complexes of sterically hindered bispyrazolylmethanes Inorganica Chimica Acta. 363: 1097-1101. DOI: 10.1016/J.Ica.2009.09.016  0.526
2010 BALDWIN JE, SPRING DR, ATKINSON CE, LEE V. ChemInform Abstract: Efficient Synthesis of the Sponge Alkaloids Cyclostellettamines A-F. Cheminform. 30: no-no. DOI: 10.1002/chin.199911249  0.449
2010 ADLINGTON RM, BALDWIN JE, CHALLIS GL. ChemInform Abstract: Rate Enhancement in the Reduction of (2,3)-α- and (2,3)-β-Methylenepenam β-Sulfoxides. Cheminform. 30: no-no. DOI: 10.1002/chin.199906227  0.453
2010 FEKNER T, BALDWIN JE, ADLINGTON RM, SCHOFIELD CJ. ChemInform Abstract: Unusually Stable Azetidinone Sulfenic Acids. Cheminform. 29: no-no. DOI: 10.1002/chin.199850126  0.397
2010 WALTER MW, ADLINGTON RM, BALDWIN JE, SCHOFIELD CJ. ChemInform Abstract: Reaction of (Trifluoromethyl)trimethylsilane with Oxazolidin-5-ones: Synthesis of Peptidic and Nonpeptidic Trifluoromethyl Ketones. Cheminform. 29: no-no. DOI: 10.1002/chin.199850080  0.404
2010 BALDWIN JE, SPRING DR, WHITEHEAD RC. ChemInform Abstract: A Novel Diels-Alder Approach to Hydroisoquinolines. Cheminform. 29: no-no. DOI: 10.1002/chin.199843163  0.426
2010 ROBINSON JK, LEE V, CLARIDGE TDW, BALDWIN JE, SCHOFIELD CJ. ChemInform Abstract: Synthesis of (2S,3R,4S), (2S,3S,4R)-Epoxyprolines and Aminohydroxyprolines. Cheminform. 29: no-no. DOI: 10.1002/chin.199821181  0.332
2010 ADLINGTON RM, BALDWIN JE, CATTERICK D, PRITCHARD GJ. ChemInform Abstract: A Versatile Approach to Pyrimidin-4-yl Substituted α-Amino Acids from Alkynyl Ketones; the Total Synthesis of L-Lathyrine. Cheminform. 29: no-no. DOI: 10.1002/chin.199803205  0.324
2010 ADLINGTON RM, BALDWIN JE, MCCOULL W, PRITCHARD GJ, SCHOFIELD CJ, WESTWOOD NJ. ChemInform Abstract: An Investigation of the N-Arylsulfonylation of 2-Azetidinones. Cheminform. 28: no-no. DOI: 10.1002/chin.199752129  0.573
2010 ADLINGTON RM, BALDWIN JE, CHEN B, COOPER SL, MCCOULL W, PRITCHARD GJ, HOWE TJ, BECKER GW, HERMANN RB, MCNULTY AM, NEUBAUER BL. ChemInform Abstract: Design and Synthesis of Novel Monocyclic β-Lactam Inhibitors of Prostate Specific Antigen. Cheminform. 28: no-no. DOI: 10.1002/chin.199746239  0.46
2010 WALTER MW, ADLINGTON RM, BALDWIN JE, SCHOFIELD CJ. ChemInform Abstract: Synthesis of Metallo-β-lactamase Inhibitors. Cheminform. 28: no-no. DOI: 10.1002/chin.199742231  0.404
2010 THIRKETTLE JE, BALDWIN JE, EDWARDS J, GRIFFIN JP, SCHOFIELD CJ. ChemInform Abstract: The Origin of the β-Lactam Carbons of Clavulanic Acid. Cheminform. 28: no-no. DOI: 10.1002/chin.199741293  0.383
2010 BALDWIN JE, ADLINGTON RM, BRYANS JS, LLOYD MD, SEWELL TJ, SCHOFIELD CJ, BAGGALEY KH, CASSELS R. ChemInform Abstract: Chemoenzymatic Synthesis of Bicyclic γ-Lactams Using Clavaminic Acid Synthase. Cheminform. 28: no-no. DOI: 10.1002/chin.199739289  0.471
2010 WALTER MW, FELICI A, GALLENI M, SOTO RP, ADLINGTON RM, BALDWIN JE, FRERE J, GOLOLOBOV M, SCHOFIELD CJ. ChemInform Abstract: Trifluoromethyl Alcohol and Ketone Inhibitors of Metallo-β- lactamases. Cheminform. 28: no-no. DOI: 10.1002/chin.199714159  0.54
2010 FEKNER T, BALDWIN JE, ADLINGTON RM, SCHOFIELD CJ. ChemInform Abstract: Syntheses of (6S,7S)- and (6S,7R)-Deacetoxycephalosporanic Acids from 6-Aminopenicillanic Acid. Cheminform. 27: no-no. DOI: 10.1002/chin.199648262  0.376
2010 FARTHING CN, BALDWIN JE, RUSSELL AT, SCHOFIELD CJ, SPIVEY AC. ChemInform Abstract: Syntheses of (S)-β-Pyrazolylalanine and (S)-Quisqualic Acid from a Serine-Derived Aziridine. Cheminform. 27: no-no. DOI: 10.1002/chin.199642222  0.614
2010 BALDWIN JE, FARTHING CN, RUSSELL AT, SCHOFIELD CJ, SPIVEY AC. ChemInform Abstract: Use of (S)-N-tert-Butoxycarbonylaziridine-2-carboxylate Derivatives for α-Amino Acid Synthesis. Cheminform. 27: no-no. DOI: 10.1002/chin.199639222  0.654
2010 BALDWIN JE, ADLINGTON RM, MARQUESS DG, PITT AR, PORTER MJ, RUSSELL AT. ChemInform Abstract: Evidence for an Insertion-Homolysis Mechanism for Carbon-Sulfur Bond Formation in Penicillin Biosynthesis. Part 2. Incubation and Interpretation. Cheminform. 27: no-no. DOI: 10.1002/chin.199625248  0.539
2010 BALDWIN JE, ADLINGTON RM, MARQUESS DG, PITT AR, PORTER MJ, RUSSELL AT. ChemInform Abstract: Evidence for an Insertion-Homolysis Mechanism for Carbon-Sulfur Bond Formation in Penicillin Biosynthesis. Part 1. Synthesis of Tripeptide Probes. Cheminform. 27: no-no. DOI: 10.1002/chin.199625247  0.572
2010 BALDWIN JE, ADLINGTON RM, ELEND AS, SMITH ML. ChemInform Abstract: Enantiospecific Synthesis of (3R,4R)-3-Amino-1-hydroxy-4-methyl- pyrrolidin-2-one (L-687,414), an NMDA Receptor Antagonist. Cheminform. 27: no-no. DOI: 10.1002/chin.199609122  0.472
2010 WALTER MW, ADLINGTON RM, BALDWIN JE, CHUHAN J, SCHOFIELD CJ. ChemInform Abstract: Reaction of Ruppert′s Reagent (TMS-CF3) with Oxazolidinones: Synthesis of Protected α-Amino Trifluoromethylketones. Cheminform. 27: no-no. DOI: 10.1002/chin.199605231  0.451
2010 BALDWIN JE, ADLINGTON RM, BEBBINGTON D, RUSSELL AT. ChemInform Abstract: Asymmetric Total Synthesis of the Individual Diastereoisomers of Hypoglycin A. Cheminform. 26: no-no. DOI: 10.1002/chin.199512276  0.504
2010 BALDWIN JE, MACKENZIE TURNER SC, MOLONEY MG. ChemInform Abstract: Enantioselective Synthesis of Novel Functionalized Prolines via (3 + 2) Cycloadditions of a Chiral Azomethine Ylid. Cheminform. 26: no-no. DOI: 10.1002/chin.199509185  0.525
2010 BALDWIN JE, MACKENZIE TURNER SC, MOLONEY MG. ChemInform Abstract: The Synthesis of Substituted Pyrrolidines by a Samarium(II) Iodide Mediated Ring Closure. Part 1. Cheminform. 25: no-no. DOI: 10.1002/chin.199452135  0.522
2010 LAWLOR EJ, ELSON SW, HOLLAND S, CASSELS R, HODGSON JE, LLOYD MD, BALDWIN JE, SCHOFIELD CJ. ChemInform Abstract: Expression in Escherichia coli of a Clavaminic Acid Synthase Isozyme: A Trifunctional Oxygenase Involved in Clavulanic Acid Biosynthesis. Cheminform. 25: no-no. DOI: 10.1002/chin.199449054  0.387
2010 BALDWIN JE, FIELD RA, LAWRENCE CC, LEE V, ROBINSON JK, SCHOFIELD CJ. ChemInform Abstract: Substrate Specificity of Proline 4-Hydroxylase: Chemical and Enzymatic Synthesis of (2S,3R,4S)-Epoxyproline. Cheminform. 25: no-no. DOI: 10.1002/chin.199447216  0.548
2010 ADLINGTON RM, BALDWIN JE, GANSAEUER A, MCCOULL W, RUSSELL AT. ChemInform Abstract: A Study of the Intramolecular Stille Cross Coupling Reaction of Vinylstannyl Chloroformates: Application to the Synthesis of α- Methylene Lactones. Cheminform. 25: no-no. DOI: 10.1002/chin.199446062  0.525
2010 BALDWIN JE, ADLINGTON RM, MELLOR LC. ChemInform Abstract: Synthesis of Chiral Isoxazolidin-5-ones and Their Applications to the Synthesis of β-Aminoalanines and β-(N-Hydroxyamino)alanines. Cheminform. 25: no-no. DOI: 10.1002/chin.199439240  0.521
2010 BALDWIN JE, FUJISHIMA Y, GOH K, SCHOFIELD CJ. ChemInform Abstract: Enzymes of Valclavam Biosynthesis Cheminform. 25: no-no. DOI: 10.1002/chin.199434264  0.358
2010 BALDWIN JE, GOH K, SCHOFIELD CJ. ChemInform Abstract: Biosynthetic Precursors of Valclavam (I). Cheminform. 25: no-no. DOI: 10.1002/chin.199434263  0.403
2010 BALDWIN JE, ADLINGTON RM, RUSSELL AT, SMITH ML. ChemInform Abstract: Synthesis of a Biologically Active Analogue of Antibiotic A-32390A. Cheminform. 25: no-no. DOI: 10.1002/chin.199418244  0.466
2010 BALDWIN JE, CLARIDGE TDW, GOH K, KEEPING JW, SCHOFIELD CJ. ChemInform Abstract: Revised Structures for Tue 1718B (Ia) and Valclavam (Ib). Cheminform. 25: no-no. DOI: 10.1002/chin.199401305  0.312
2010 BALDWIN JE, SPIVEY AC, SCHOFIELD CJ, SWEENEY JB. ChemInform Abstract: Amino Acid Synthesis via Ring Opening of N-Sulfonyl Aziridine-2- carboxylate Esters with Organometallic Reagents. Cheminform. 24: no-no. DOI: 10.1002/chin.199346123  0.66
2010 BALDWIN JE, HULME C, SCHOFIELD CJ, EDWARDS AJ. ChemInform Abstract: Synthesis of Potential β-Turn Bicyclic Dipeptide Mimetics. Cheminform. 24: no-no. DOI: 10.1002/chin.199336201  0.412
2010 BALDWIN JE, MOLONEY MG, PARSONS AF. ChemInform Abstract: Intramolecular Cobalt Cyclization for the Construction of Substituted Pyrrolidines. Cheminform. 24: no-no. DOI: 10.1002/chin.199308108  0.533
2010 BALDWIN JE, LYNCH GP, SCHOFIELD CJ. ChemInform Abstract: Isopenicillin N Synthase: A New Mode of Reactivity. Cheminform. 24: no-no. DOI: 10.1002/chin.199306060  0.355
2010 BALDWIN JE, HULME C, SCHOFIELD CJ. ChemInform Abstract: Syntheses of cis- and trans-Pyrrolidine-2,5-dicarboxylic Acids. Cheminform. 23: no-no. DOI: 10.1002/chin.199239275  0.381
2010 BALDWIN JE, LEE V, SCHOFIELD CJ. ChemInform Abstract: Synthesis of a Bicyclic γ-Lactam Dipeptide Analogue. Cheminform. 23: no-no. DOI: 10.1002/chin.199234157  0.466
2010 BALDWIN JE, ADLINGTON RM, CROUCH NP, SCHOFIELD CJ, TURNER NJ, APLIN RT. ChemInform Abstract: Cephalosporin Biosynthesis: A Branched Pathway Sensitive to an Isotope Effect. Cheminform. 23: no-no. DOI: 10.1002/chin.199211062  0.324
2010 BALDWIN JE, ADLINGTON RM, CROUCH NP, KEEPING JW, LEPPARD SW, PITLIK J, SCHOFIELD CJ, SOBEY WJ, WOOD ME. ChemInform Abstract: Studies on the Mechanism of Deacetoxy-Deacetylcephalosporin C Synthase Using Cyclopropyl Substituted Cephalosporin Probes. Cheminform. 23: no-no. DOI: 10.1002/chin.199210297  0.381
2010 BALDWIN JE, ADLINGTON RM, RAMCHARITAR SH. ChemInform Abstract: Intramolecular Palladium-Catalyzed Cross Coupling. A Route to γ- Oxo-α,β-Unsaturated Macrocycles. Cheminform. 23: no-no. DOI: 10.1002/chin.199209246  0.501
2010 BALDWIN JE, BRADLEY M, TURNER NJ, ADLINGTON RM, PITT AR, DEROME AE. ChemInform Abstract: Enzymic Conversion of Deuterated Analogues of δ-L-α- Aminoadipoyl-L-cysteinyl-D-allylglycine, an Unnatural Substrate for Isopenicillin N Synthase: A Unified Theory of Second Ring Closure Cheminform. 23: no-no. DOI: 10.1002/chin.199204258  0.545
2010 BALDWIN JE, BRADLEY M, TURNER NJ, ADLINGTON RM, PITT AR, SHERIDAN H. ChemInform Abstract: Synthesis of δ-L-α-Aminoadipoyl-L-cysteinyl-D-allylglycine (I), and Eight Deuterated Analogues, Substrates for the Investigation of the Mechanism of Action of Isopenicillin N Synthase. Cheminform. 23: no-no. DOI: 10.1002/chin.199204257  0.547
2010 BALDWIN JE, MOLONEY MG, SHIM SB. ChemInform Abstract: L-Pyroglutamic Acid as a Chiral Starting Material for Asymmetric Synthesis. Cheminform. 23: no-no. DOI: 10.1002/chin.199202210  0.55
2010 BALDWIN JE, ADLINGTON RM, GODFREY CRA, GOLLINS DW, SCHOFIELD CJ. ChemInform Abstract: The Stereospecific Synthesis of Alahopcin. Cheminform. 22: no-no. DOI: 10.1002/chin.199143234  0.447
2010 BALDWIN JE, JESUDASON CD, MOLONEY MG, MORGAN DR, PRATT AJ. ChemInform Abstract: The Synthesis of Substituted Aryl Diazirines. A Bifunctional Reagent Suitable for Application to Photoaffinity Labelling Studies. Cheminform. 22: no-no. DOI: 10.1002/chin.199142155  0.534
2010 BALDWIN JE, BRADLEY M, ABBOTT SD, ADLINGTON RM. ChemInform Abstract: New Penicillins from Isopenicillin N Synthase. Cheminform. 22: no-no. DOI: 10.1002/chin.199140254  0.475
2010 BALDWIN JE, ADLINGTON RM, BRYANS JS, BRINGHEN AO, COATES JB, CROUCH NP, LLOYD MD, SCHOFIELD CJ, ELSON SW, BAGGALEY KH, CASSELS R, NICHOLSON N. ChemInform Abstract: Isolation of Dihydroclavaminic Acid (I), an Intermediate in the Biosynthesis of Clavulanic Acid Cheminform. 22: no-no. DOI: 10.1002/chin.199135272  0.388
2010 BALDWIN JE, SPIVEY AC, SCHOFIELD CJ. ChemInform Abstract: Cyclic Sulfamidates: New Synthetic Precursors for β- Functionalized α-Amino Acids. Cheminform. 22: no-no. DOI: 10.1002/chin.199116260  0.62
2010 BALDWIN JE, BRADLEY M, ADLINGTON RM, NORRIS WJ, TURNER NJ. ChemInform Abstract: Further Evidence for the Involvement of a Monocyclic β-Lactam in the Enzymatic Conversion of δ-L-α-Aminoadipoyl-L-cysteinyl- D-valine into Isopenicillin N. Cheminform. 22: no-no. DOI: 10.1002/chin.199116259  0.525
2010 BALDWIN JE, MOLONEY MG, PARSONS AF. ChemInform Abstract: Enantioselective Synthesis of Kainoid Analogues by Cobalt-Mediated Cyclizations. Cheminform. 22: no-no. DOI: 10.1002/chin.199112312  0.559
2010 BALDWIN JE, LOWE C, SCHOFIELD CJ. ChemInform Abstract: The Synthesis of Potential γ-Lactam Antibiotics Containing a Cycloserine Nucleus. Cheminform. 22: no-no. DOI: 10.1002/chin.199111164  0.403
2010 BALDWIN JE, BRADLEY M, ABBOTT SD, ADLINGTON RM. ChemInform Abstract: Formation of Novel Unsaturated Side Chain Penicillins with Isopenicillin N Synthase. Cheminform. 22: no-no. DOI: 10.1002/chin.199104090  0.491
2010 BALDWIN JE, MOLONEY MG, PARSONS AF. ChemInform Abstract: Enantioselective Kainoid Synthesis by Cobalt-Mediated Cyclisation of an Amino Acid Derivative. Cheminform. 22: no-no. DOI: 10.1002/chin.199103311  0.556
2010 BALDWIN JE, MCCONNAUGHIE AW, MOLONEY MG, PRATT AJ, SHIM SB. ChemInform Abstract: New Photolabile Phosphate Protecting Groups. Cheminform. 22: no-no. DOI: 10.1002/chin.199101138  0.445
2009 Ge W, Clifton IJ, Howard-Jones AR, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. Structural studies on the reaction of isopenicillin N synthase with a sterically demanding depsipeptide substrate analogue Chembiochem. 10: 2025-2031. PMID 19598184 DOI: 10.1002/Cbic.200900080  0.807
2008 Ge W, Clifton IJ, Stok JE, Adlington RM, Baldwin JE, Rutledge PJ. Isopenicillin N synthase mediates thiolate oxidation to sulfenate in a depsipeptide substrate analogue: Implications for oxygen binding and a link to nitrile hydratase? Journal of the American Chemical Society. 130: 10096-10102. PMID 18620394 DOI: 10.1021/Ja8005397  0.795
2008 Eade SJ, Walter MW, Byrne C, Odell B, Rodriguez R, Baldwin JE, Adlington RM, Moses JE. Biomimetic synthesis of pyrone-derived natural products: exploring chemical pathways from a unique polyketide precursor. The Journal of Organic Chemistry. 73: 4830-9. PMID 18517253 DOI: 10.1021/Jo800220W  0.675
2007 Stewart AC, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. A cyclobutanone analogue mimics penicillin in binding to isopenicillin N synthase Chembiochem. 8: 2003-2007. PMID 17907118 DOI: 10.1002/Cbic.200700176  0.785
2007 Howard-Jones AR, Elkins JM, Clifton IJ, Roach PL, Adlington RM, Baldwin JE, Rutledge PJ. Interactions of isopenicillin N synthase with cyclopropyl-containing substrate analogues reveal new mechanistic insight Biochemistry. 46: 4755-4762. PMID 17397141 DOI: 10.1021/Bi062314Q  0.82
2007 Baldwin JE, Pritchard GJ, Rathmell RE. Synthesis of Novel Unsymmetrical and Symmetrical Diacetylenic Ketones Synthetic Communications. 30: 3833-3847. DOI: 10.1080/00397910008086940  0.343
2007 Fenlon TW, Schwaebisch D, Mayweg AVW, Lee V, Adlington RM, Baldwin JE. Studies towards the synthesis of lindenene: Unexpected stereochemical outcome of an intramolecular cyclopropanation reaction and synthesis of (±)-epi-lindenene and (±)-iso-lindenene Synlett. 2679-2682. DOI: 10.1055/S-2007-991069  0.53
2007 Chen R, Lee V, Adlington RM, Baldwin JE. A facile synthesis of ethyl 2-acetamido-4-methylenehex-5-enoate, a versatile Diels-Alder synthon for the parallel synthesis of novel α-amino acid derivatives Synthesis. 113-117. DOI: 10.1055/S-2006-958929  0.618
2007 Shorey BJ, Lee V, Baldwin JE. Synthesis of the Arctic sponge alkaloid viscosaline and the marine sponge alkaloid theonelladin C Tetrahedron. 63: 5587-5592. DOI: 10.1016/J.Tet.2007.04.020  0.385
2007 Rodriguez R, Adlington RM, Eade SJ, Walter MW, Baldwin JE, Moses JE. Total synthesis of cyercene A and the biomimetic synthesis of (±)-9,10-deoxytridachione and (±)-ocellapyrone A Tetrahedron. 63: 4500-4509. DOI: 10.1016/J.Tet.2007.03.057  0.694
2007 Rodriguez R, Adlington RM, Eade SJ, Walter MW, Baldwin JE, Moses JE. Total Synthesis of Cyercene A (I) and the Biomimetic Synthesis of (.+-.)-9,10-Deoxytridachione (II) and (.+-.)-Ocellapyrone A. Cheminform. 38. DOI: 10.1002/chin.200735216  0.579
2006 Kirkham JED, Lee V, Baldwin JE. Stereochemical reassignment of Mehta and Kundu's spiculoic acid A analogue Organic Letters. 8: 5537-5540. PMID 17107066 DOI: 10.1021/Ol062361A  0.351
2006 Kirkham JED, Lee V, Baldwin JE. Biomimetic synthesis of marine sponge metabolite spiculoic acid A and establishment of the absolute configuration of the natural product Chemical Communications. 2863-2865. PMID 17007398 DOI: 10.1039/B607035C  0.397
2006 Daruzzaman A, Clifton IJ, Adlington RM, Baldwin JE, Rutledge PJ. Unexpected oxidation of a depsipeptide substrate analogue in crystalline isopenicillin N synthase Chembiochem. 7: 351-358. PMID 16444759 DOI: 10.1002/Cbic.200500282  0.808
2006 Goundry WRF, Lee V, Baldwin JE. Synthesis of excitatory amino acid analogues Synlett. 2407-2410. DOI: 10.1055/S-2006-950399  0.3
2006 Lawrence AL, Wegner HA, Jacobsen MF, Adlington RM, Baldwin JE. Investigations towards the synthesis of (-)-coprinolone, via a thermal 8π-6π electrocyclization cascade of 1,5,7-trien-4-ones Tetrahedron Letters. 47: 8717-8720. DOI: 10.1016/J.Tetlet.2006.10.021  0.677
2006 Smith CD, Tchabanenko K, Adlington RM, Baldwin JE. Synthesis of linked heterocycles via use of bis-acetylenic compounds Tetrahedron Letters. 47: 3209-3212. DOI: 10.1016/J.Tetlet.2006.03.052  0.567
2006 Tchabanenko K, Taylor MGO, Adlington RM, Baldwin JE. Synthesis of substituted pyrano[3,2-c]pyridines via Diels-Alder reaction of 3-methylenepyridin-4-one Tetrahedron Letters. 47: 39-41. DOI: 10.1016/J.Tetlet.2005.10.119  0.591
2006 Comméiras L, Moses JE, Adlington RM, Baldwin JE, Cowley AR, Baker CM, Albrecht B, Grant GH. Total synthesis of the epoxyquinol dimer (+)-panepophenanthrin: application of a diastereospecific biomimetic Diels-Alder dimerisation Tetrahedron. 62: 9892-9901. DOI: 10.1016/J.Tet.2006.08.010  0.709
2006 Irlapati NR, Baldwin JE, Adlington RM, Pritchard GJ, Cowley AR. Studies towards the biomimetic synthesis of pyridomacrolidin Tetrahedron. 62: 4603-4614. DOI: 10.1016/J.Tet.2006.01.090  0.588
2006 Jacobsen MF, Moses JE, Adlington RM, Baldwin JE. The biomimetic synthesis of SNF4435C and SNF4435D, and the total synthesis of the polyene metabolites aureothin, N-acetyl-aureothamine and spectinabilin Tetrahedron. 62: 1675-1689. DOI: 10.1016/J.Tet.2005.11.058  0.687
2006 He J, Tchabanenko K, Adlington RM, Cowley AR, Baldwin JE. New domino silyl enol ether reactions in the synthesis of a tetrodecamycin fragment European Journal of Organic Chemistry. 4003-4013. DOI: 10.1002/Ejoc.200600346  0.598
2006 Jacobsen MF, Moses JE, Adlington RM, Baldwin JE. The Biomimetic Synthesis of SNF4435C (I) and SNF4435D (II), and the Total Synthesis of the Polyene Metabolites Aureothin (IIIa), N-Acetyl-aureothamine (IIIb) and Spectinabilin (IV). Cheminform. 37. DOI: 10.1002/chin.200625206  0.593
2005 Rodriguez R, Moses JE, Adlington RM, Baldwin JE. A new and efficient method for o-quinone methide intermediate generation: application to the biomimetic synthesis of the benzopyran derived natural products (+/-)-lucidene and (+/-)-alboatrin. Organic & Biomolecular Chemistry. 3: 3488-95. PMID 16172685 DOI: 10.1039/B508972G  0.697
2005 Howard-Jones AR, Rutledge PJ, Clifton IJ, Adlington RM, Baldwin JE. Unique binding of a non-natural L,L,L-substrate by isopenicillin N synthase Biochemical and Biophysical Research Communications. 336: 702-708. PMID 16143309 DOI: 10.1016/J.Bbrc.2005.08.155  0.783
2005 Eade SJ, Adlington RM, Cowley AR, Walter MW, Baldwin JE. A novel oxidative rearrangement of 6-methoxypyran-2-ones. Organic Letters. 7: 3705-7. PMID 16092855 DOI: 10.1021/Ol0513490  0.563
2005 Jacobsen MF, Moses JE, Adlington RM, Baldwin JE. The total synthesis of spectinabilin and its biomimetic conversion to SNF4435C and SNF4435D. Organic Letters. 7: 2473-6. PMID 15932226 DOI: 10.1021/Ol0507874  0.684
2005 Long AJ, Clifton IJ, Roach PL, Baldwin JE, Rutledge PJ, Schofield CJ. Structural studies on the reaction of isopenicillin N synthase with the truncated substrate analogues delta-(L-alpha-aminoadipoyl)-L-cysteinyl-glycine and delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alanine. Biochemistry. 44: 6619-28. PMID 15850395 DOI: 10.1021/Bi047478Q  0.769
2005 Adamo MFA, Baldwin JE, Adlington RM. Application of bis-acetylenic ketones in synthesis: One-pot preparation of the 1,2,4-triazepine and oxatriazaindenone cores Journal of Organic Chemistry. 70: 3307-3308. PMID 15823002 DOI: 10.1021/Jo047991+  0.565
2005 Moses JE, Adlington RM, Rodriguez R, Eade SJ, Baldwin JE. Biomimetic synthesis of (+/-)-9,10-deoxytridachione. Chemical Communications (Cambridge, England). 1687-9. PMID 15791299 DOI: 10.1039/B418988D  0.698
2005 Mee SP, Lee V, Baldwin JE. Significant enhancement of the Stille reaction with a new combination of reagents-copper(I) iodide with cesium fluoride. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 3294-308. PMID 15786503 DOI: 10.1002/Chem.200401162  0.32
2005 Jacobsen MF, Moses JE, Adlington RM, Baldwin JE. A short total synthesis of aureothin and N-acetylaureothamine. Organic Letters. 7: 641-4. PMID 15704914 DOI: 10.1021/Ol047594L  0.713
2005 Tchabanenko K, Adlington RM, Cowley AR, Baldwin JE. Biomimetic total synthesis of (+)-himbacine Organic Letters. 7: 585-588. PMID 15704900 DOI: 10.1021/Ol047676+  0.592
2005 Eade SJ, Adlington RM, Cowley AR, Walter MW, Baldwin JE. A novel oxidative rearrangement of 6-methoxypyran-2-ones Organic Letters. 7: 3705-3707. DOI: 10.1021/ol0513490  0.422
2005 Bagal SK, Adlington RM, Brown RAB, Baldwin JE. Regioselectivity of dimerisation of butenolides via captodative stabilised radicaloid intermediates Tetrahedron Letters. 46: 4633-4637. DOI: 10.1016/J.Tetlet.2005.04.125  0.517
2005 Tchabanenko K, Chesworth R, Parker JS, Anand NK, Russell AT, Adlington RM, Baldwin JE. Biomimetic approach to Galbulimina type I alkaloids Tetrahedron. 61: 11649-11656. DOI: 10.1016/J.Tet.2005.09.050  0.528
2005 Kirkham JED, Courtney TDL, Lee V, Baldwin JE. Asymmetric synthesis of cytotoxic sponge metabolites R-strongylodiols A and B and an analogue Tetrahedron. 61: 7219-7232. DOI: 10.1016/J.Tet.2005.05.034  0.301
2005 Celanire S, Marlin F, Baldwin JE, Adlington RM. Base-assisted intramolecular 6-acetoxypyranone-acetylene [5+2] cycloaddition. Synthesis and reactivity of novel oxa-tricyclo[5.3.1.0 1,5]undecenones Tetrahedron. 61: 3025-3032. DOI: 10.1016/J.Tet.2005.01.113  0.58
2005 Baldwin JE, Adlington RM, Sham VWW, Marquez R, Bulger PG. Biomimetic synthesis of (±)-aculeatin D Tetrahedron. 61: 2353-2363. DOI: 10.1016/J.Tet.2005.01.021  0.578
2005 Irlapati NR, Baldwin JE, Adlington RM, Pritchard GJ, Cowley AR. Regio- and stereospecific [3+2] cycloaddition of an unusual nitrone derived from a N-hydroxy-2-pyridone with medium ring enones Tetrahedron. 61: 1773-1784. DOI: 10.1016/J.Tet.2004.12.019  0.561
2005 Romeril SP, Lee V, Baldwin JE, Claridge TDW. On the synthesis of pyrinodemin A. Part 1: The location of the olefin Tetrahedron. 61: 1127-1140. DOI: 10.1016/J.Tet.2004.11.051  0.344
2005 Krall JA, Rutledge PJ, Baldwin JE. Design and synthesis of an isopenicillin N synthase mimic Tetrahedron. 61: 137-143. DOI: 10.1016/J.Tet.2004.10.041  0.699
2005 Jacobsen MF, Moses JE, Adlington RM, Baldwin JE. The Total Synthesis of Spectinabilin (I) and Its Biomimetic Conversion to SNF4435C (II) and SNF4435D (III). Cheminform. 36. DOI: 10.1002/chin.200544226  0.648
2005 Jacobsen MF, Moses JE, Adlington RM, Baldwin JE. A Short Total Synthesis of Aureothin (Ia) and N-Acetylaureothamine (Ib). Cheminform. 36. DOI: 10.1002/chin.200528208  0.577
2004 Bagal SK, Adlington RM, Baldwin JE, Marquez R. Dimerization of butenolide structures. A biomimetic approach to the dimeric sesquiterpene lactones (±)-biatractylolide and (±)- biepiasterolide Journal of Organic Chemistry. 69: 9100-9108. PMID 15609943 DOI: 10.1021/Jo0488053  0.452
2004 Schwaebisch D, Tchabanenko K, Adlington RM, Cowley AM, Baldwin JE. Biomimetic synthesis of the pyrrolobenzoxazine core of paeciloxazine. Chemical Communications (Cambridge, England). 2552-3. PMID 15543275 DOI: 10.1039/B412300J  0.574
2004 Rodriguez R, Adlington RM, Moses JE, Cowley A, Baldwin JE. A new and efficient method for o-quinone methide intermediate generation: application to the biomimetic synthesis of (+/-)-Alboatrin. Organic Letters. 6: 3617-9. PMID 15387562 DOI: 10.1021/Ol048479D  0.678
2004 Grummitt AR, Rutledge PJ, Clifton IJ, Baldwin JE. Active-site-mediated elimination of hydrogen fluoride from a fluorinated substrate analogue by isopenicillin N synthase. The Biochemical Journal. 382: 659-66. PMID 15175003 DOI: 10.1042/Bj20040529  0.768
2004 Lloyd MD, Lipscomb SJ, Hewitson KS, Hensgens CM, Baldwin JE, Schofield CJ. Controlling the substrate selectivity of deacetoxycephalosporin/deacetylcephalosporin C synthase. The Journal of Biological Chemistry. 279: 15420-6. PMID 14734549 DOI: 10.1074/Jbc.M313928200  0.435
2004 Schwaebisch D, Tchabanenko K, Adlington RM, Cowley AM, Baldwin JE. Biomimetic synthesis of the pyrrolobenzoxazine core of paeciloxazine Chemical Communications. 10: 2552-2553. DOI: 10.1039/b412300j  0.499
2004 Kyei AS, Tchabanenko K, Baldwin JE, Adlington RM. Radical dearomatising spirocyclisations onto the C-2 position of benzofuran and indole Tetrahedron Letters. 45: 8931-8934. DOI: 10.1016/J.Tetlet.2004.09.148  0.535
2004 Moses JE, Baldwin JE, Adlington RM. An efficient synthesis of cyercene A Tetrahedron Letters. 45: 6447-6448. DOI: 10.1016/J.Tetlet.2004.06.125  0.695
2004 Kirkham JE, Courtney TD, Lee V, Baldwin JE. Asymmetric synthesis of cytotoxic sponge metabolites R -strongylodiols A and B Tetrahedron Letters. 45: 5645-5647. DOI: 10.1016/J.Tetlet.2004.05.122  0.329
2004 Irlapati NR, Adlington RM, Conte A, Pritchard GJ, Marquez R, Baldwin JE. Total synthesis of pyridovericin Tetrahedron. 60: 9307-9317. DOI: 10.1016/J.Tet.2004.07.035  0.58
2004 Mee SPH, Lee V, Baldwin JE, Cowley A. Total synthesis of 5,5′,6,6′-tetrahydroxy-3,3′-biindolyl, the proposed structure of a potent antioxidant found in beetroot (Beta vulgaris) Tetrahedron. 60: 3695-3712. DOI: 10.1016/J.Tet.2004.02.043  0.307
2004 Brückner S, Baldwin JE, Adlington RM, Claridge TDW, Odell B. Thermal and palladium catalyzed pericyclic rearrangements of a pentaene ester Tetrahedron. 60: 2785-2788. DOI: 10.1016/J.Tet.2004.01.078  0.543
2004 Adamo MFA, Adlington RM, Baldwin JE, Day AL. A parallel synthesis approach towards a family of C-nucleosides Tetrahedron. 60: 841-849. DOI: 10.1016/J.Tet.2003.11.055  0.537
2004 Commeiras L, Woodcock SC, Baldwin JE, Adlington RM, Cowley AR, Wilkinson PJ. New access to the 1H-pyrazolo[4,3-c]pyridine core from bis-acetylenic-N- benzoylhydrazones Tetrahedron. 60: 933-938. DOI: 10.1016/J.Tet.2003.11.036  0.528
2003 Moses JE, Baldwin JE, Brückner S, Eade SJ, Adlington RM. Biomimetic studies on polyenes. Organic & Biomolecular Chemistry. 1: 3670-84. PMID 14649898 DOI: 10.1039/B306933H  0.705
2003 Elkins JM, Rutledge PJ, Burzlaff NI, Clifton IJ, Adlington RM, Roach PL, Baldwin JE. Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue. Organic & Biomolecular Chemistry. 1: 1455-60. PMID 12926272 DOI: 10.1039/B212270G  0.818
2003 Bagal SK, Adlington RM, Baldwin JE, Marquez R, Cowley A. Biomimetic synthesis of biatractylolide and biepiasterolide Organic Letters. 5: 3049-3052. PMID 12916978 DOI: 10.1021/Ol035022F  0.53
2003 Moses JE, Commeiras L, Baldwin JE, Adlington RM. Total synthesis of panepophenanthrin. Organic Letters. 5: 2987-8. PMID 12916962 DOI: 10.1021/Ol0349817  0.709
2003 Irlapati NR, Baldwin JE, Adlington RM, Pritchard GJ, Cowley A. An unusual oxidative cyclization: Studies towards the biomimetic synthesis of pyridomacrolidin Organic Letters. 5: 2351-2354. PMID 12816446 DOI: 10.1021/Ol034736N  0.518
2003 Long AJ, Clifton IJ, Roach PL, Baldwin JE, Schofield CJ, Rutledge PJ. Structural studies on the reaction of isopenicillin N synthase with the substrate analogue delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-alpha-aminobutyrate. The Biochemical Journal. 372: 687-93. PMID 12622704 DOI: 10.1042/Bj20021627  0.791
2003 Moses JE, Baldwin JE, Marquez R, Adlington RM, Claridge TD, Odell B. Biomimetic synthesis of the crispatene core. Organic Letters. 5: 661-3. PMID 12605484 DOI: 10.1021/Ol020242Z  0.669
2003 Baldwin JE, Adlington RM, Wilkinson PJ, Marquez R, Adamo MFA. Studies towards the biomimetic synthesis of ginsenoyne L; efficient synthesis of 2′-epi-ginsenoyne L Heterocycles. 59: 81-85. DOI: 10.3987/Com-02-S25  0.597
2003 Mee SPH, Lee V, Baldwin JE. An efficient synthesis of 3,4-bis(tri-n-butylstannyl)furan Synthetic Communications. 33: 3205-3209. DOI: 10.1081/Scc-120023442  0.358
2003 Elkins JM, Rutledge PJ, Burzlaff NI, Clifton IJ, Adlington RM, Roach PL, Baldwin JE. Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue Organic and Biomolecular Chemistry. 1: 1455-1460. DOI: 10.1039/b212270g  0.798
2003 Moses JE, Baldwin JE, Adlington RM, Cowley AR, Marquez R. Thermally induced cascade pericyclic reaction pathways from tetraene esters Tetrahedron Letters. 44: 6625-6627. DOI: 10.1016/S0040-4039(03)01673-3  0.675
2003 Bagal SK, Adlington RM, Marquez R, Cowley AR, Baldwin JE. Studies towards the biomimetic synthesis of bisesquiterpene lactones Tetrahedron Letters. 44: 4993-4996. DOI: 10.1016/S0040-4039(03)01172-9  0.568
2003 Baldwin JE, Mayweg AVW, Pritchard GJ, Adlington RM. Expedient synthesis of a highly substituted tropolone via a 3-oxidopyrylium [5+2] cycloaddition reaction Tetrahedron Letters. 44: 4543-4545. DOI: 10.1016/S0040-4039(03)00987-0  0.609
2003 Adamo MFA, Adlington RM, Baldwin JE, Pritchard GJ, Rathmell RE. Practical routes to diacetylenic ketones and their application for the preparation of alkynyl substituted pyridines, pyrimidines and pyrazoles Tetrahedron. 59: 2197-2205. DOI: 10.1016/S0040-4020(03)00244-8  0.574
2003 Goundry WRF, Baldwin JE, Lee V. Total synthesis of cytotoxic sponge alkaloids hachijodines F and G Tetrahedron. 59: 1719-1729. DOI: 10.1016/S0040-4020(03)00115-7  0.302
2003 Romeril SP, Lee V, Baldwin JE, Claridge TDW, Odell B. Investigation into the absolute stereochemistry of the marine sponge alkaloid pyrinodemin A Tetrahedron Letters. 44: 7757-7761. DOI: 10.1016/J.Tetlet.2003.08.097  0.308
2003 Brückner S, Baldwin JE, Moses J, Adlington RM, Cowley AR. Mechanistic evidence supporting the biosynthesis of photodeoxytridachione Tetrahedron Letters. 44: 7471-7473. DOI: 10.1016/J.Tetlet.2003.08.021  0.708
2003 Ferguson AC, Adlington RM, Martyres DH, Rutledge PJ, Cowley A, Baldwin JE. Total synthesis of a novel 2-thiabicyclo[3.2.0]heptan-6-one analogue of penicillin N Tetrahedron. 59: 8233-8243. DOI: 10.1016/J.Tet.2003.08.004  0.716
2002 Gygi CM, Leibovitch IY, Adlington R, Baldwin JE, Chen B, Mccoull W, Pritchard GJ, Becker GW, Dixon EP, Little SP, Sutkowski DM, Teater C, Neubauer BL. Prostate-specific antigen (PSA)-mediated proliferation, androgenic regulation and inhibitory effects of LY312340 in HOS-TE85 (TE85) human osteosarcoma cells. Anticancer Research. 22: 2725-32. PMID 12529988  0.403
2002 Rutledge PJ, Burzlaff NI, Elkins JM, Pickford M, Baldwin JE, Roach PL. A device for the high-pressure oxygenation of protein crystals. Analytical Biochemistry. 308: 265-8. PMID 12419338 DOI: 10.1016/S0003-2697(02)00246-4  0.778
2002 Moses JE, Baldwin JE, Marquez R, Adlington RM, Cowley AR. Studies on the biomimetic synthesis of SNF4435 C and D. Organic Letters. 4: 3731-4. PMID 12375930 DOI: 10.1021/Ol020157R  0.72
2002 Adlington RM, Baldwin JE, Mayweg AVW, Pritchard GJ. Biomimetic cycloaddition approach to tropolone natural products via a tropolone ortho-quinone methide Organic Letters. 4: 3009-3011. PMID 12182611 DOI: 10.1021/Ol026467R  0.51
2002 Baldwin JE, Adlington RM, Conte A, Irlapati NR, Marquez R, Pritchard GJ. Total synthesis of pyridovericin: Studies toward the biomimetic synthesis of pyridomacrolidin Organic Letters. 4: 2125-2127. PMID 12074648 DOI: 10.1021/Ol0200504  0.597
2002 Lipscomb SJ, Lee HJ, Mukherji M, Baldwin JE, Schofield CJ, Lloyd MD. The role of arginine residues in substrate binding and catalysis by deacetoxycephalosporin C synthase. European Journal of Biochemistry / Febs. 269: 2735-9. PMID 12047382 DOI: 10.1046/J.1432-1033.2002.02945.X  0.383
2002 Elkins JM, Ryle MJ, Clifton IJ, Dunning Hotopp JC, Lloyd JS, Burzlaff NI, Baldwin JE, Hausinger RP, Roach PL. X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates. Biochemistry. 41: 5185-92. PMID 11955067 DOI: 10.1021/Bi016014E  0.791
2002 Adlington RM, Baldwin JE, Cox RJ, Pritchard GJ. A rapid entry to natural and unnatural disubstituted maleic anhydrides Synlett. 820-822. DOI: 10.1055/S-2002-25344  0.534
2002 Romeril SP, Lee V, Claridge TDW, Baldwin JE. Synthesis of a possible structure of pyrinodemin A Tetrahedron Letters. 43: 327-329. DOI: 10.1016/S0040-4039(01)02117-7  0.318
2002 Baldwin JE, Bulger PG, Marquez R. Fast and efficient synthesis of novel fumagillin analogues Tetrahedron. 58: 5441-5452. DOI: 10.1016/S0040-4020(02)00514-8  0.373
2001 Ogle JM, Clifton IJ, Rutledge PJ, Elkins JM, Burzlaff NI, Adlington RM, Roach PL, Baldwin JE. Alternative oxidation by isopenicillin N synthase observed by X-ray diffraction. Chemistry & Biology. 8: 1231-7. PMID 11755401 DOI: 10.1016/S1074-5521(01)00090-4  0.819
2001 Clifton IJ, Hsueh LC, Baldwin JE, Harlos K, Schofield CJ. Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases. European Journal of Biochemistry / Febs. 268: 6625-36. PMID 11737217 DOI: 10.1046/J.0014-2956.2001.02617.X  0.63
2001 Hamilton CS, Yasuhara A, Baldwin JE, Lloyd MD, Rutledge PJ. Contrasting fates for 6-α-methylpenicillin N upon oxidation by deacetoxycephalosporin C synthase (DAOCS) and deacetoxy/deacetylcephalosporin C synthase (DAOC/DACS) Bioorganic and Medicinal Chemistry Letters. 11: 2511-2514. PMID 11549458 DOI: 10.1016/S0960-894X(01)00470-X  0.622
2001 Dubus A, Lloyd MD, Lee HJ, Schofield CJ, Baldwin JE, Frere JM. Probing the penicillin sidechain selectivity of recombinant deacetoxycephalosporin C synthase. Cellular and Molecular Life Sciences : Cmls. 58: 835-43. PMID 11437242 DOI: 10.1007/Pl00000904  0.428
2001 Lee HJ, Lloyd MD, Harlos K, Clifton IJ, Baldwin JE, Schofield CJ. Kinetic and crystallographic studies on deacetoxycephalosporin C synthase (DAOCS). Journal of Molecular Biology. 308: 937-48. PMID 11352583 DOI: 10.1006/Jmbi.2001.4649  0.628
2001 Baldwin JE, Romeril SP, Lee V, Claridge TD. Studies toward the total synthesis of the cytotoxic sponge alkaloid pyrinodemin A. Organic Letters. 3: 1145-8. PMID 11348180 DOI: 10.1021/Ol015646Q  0.346
2001 Adlington RM, Baldwin JE, Becker GW, Chen B, Cheng L, Cooper SL, Hermann RB, Howe TJ, McCoull W, McNulty AM, Neubauer BL, Pritchard GJ. Design, synthesis, and proposed active site binding analysis of monocyclic 2-azetidinone inhibitors of prostate specific antigen. Journal of Medicinal Chemistry. 44: 1491-508. PMID 11334560 DOI: 10.1021/Jm000145G  0.446
2001 Baldwin JE, Fryer AM, Pritchard GJ. Parallel synthesis of novel heteroaromatic acromelic acid analogues from kainic acid. The Journal of Organic Chemistry. 66: 2588-96. PMID 11304175 DOI: 10.1021/Jo000846L  0.396
2001 Lee HJ, Lloyd MD, Clifton IJ, Harlos K, Dubus A, Baldwin JE, Frere JM, Schofield CJ. Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase. The role of arginine 258. The Journal of Biological Chemistry. 276: 18290-5. PMID 11279000 DOI: 10.1074/Jbc.M100085200  0.631
2001 Baldwin JE, Pritchard GJ, Rathmell RE. The reactions of diacetylenic ketones with nitrogen nucleophiles; facile preparation of alkynyl substituted pyrimidines and pyrazoles Journal of the Chemical Society. Perkin Transactions 1. 2906-2908. DOI: 10.1039/B108645F  0.393
2001 Adlington RM, Baldwin JE, Catterick D, Pritchard GJ. The efficient, enantioselective synthesis of quinoxaline, pyrazine and 1,2,4-triazine substituted α-amino acids from vicinal tricarbonyls Journal of the Chemical Society. Perkin Transactions 1. 668-679. DOI: 10.1039/B010134F  0.599
2001 Baldwin JE, Adlington RM, Roussi F, Bulger PG, Marquez R, Mayweg AVW. Studies towards the biomimetic synthesis of the nonadrides CP-225,917 and CP-263,114 Tetrahedron. 57: 7409-7416. DOI: 10.1016/S0040-4020(01)00706-2  0.55
2001 Martyres DH, Baldwin JE, Adlington RM, Lee V, Probert MR, Watkin DJ. Synthesis of a novel thiabicyclo[3.2.0]heptan-6-one analogue of penicillin Tetrahedron. 57: 4999-5007. DOI: 10.1016/S0040-4020(01)00430-6  0.607
2000 Dubus A, Sami M, Brown TJ, Schofield CJ, Baldwin JE, Frère JM. Studies of isopenicillin N synthase enzymatic properties using a continuous spectrophotometric assay. Febs Letters. 485: 142-6. PMID 11094156 DOI: 10.1016/S0014-5793(00)02221-3  0.442
2000 Baldwin JE, Pritchard GJ, Williamson DS. The synthesis of 4-arylsulfanyl-substituted kainoid analogues from trans-4-hydroxy-L-proline. Bioorganic & Medicinal Chemistry Letters. 10: 1927-9. PMID 10987419 DOI: 10.1016/S0960-894X(00)00352-8  0.427
2000 Baldwin JE, Fryer AM, Pritchard GJ. Novel C-4 heteroaromatic kainoid analogues: a parallel synthesis approach. Bioorganic & Medicinal Chemistry Letters. 10: 309-11. PMID 10698461 DOI: 10.1016/S0960-894X(99)00690-3  0.373
2000 Zhang Z, Ren J, Stammers DK, Baldwin JE, Harlos K, Schofield CJ. Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase. Nature Structural Biology. 7: 127-33. PMID 10655615 DOI: 10.1038/72398  0.422
2000 Walter MW, Thaker N, Baldwin JE, Muller M, Schofield CJ. The reaction of TMS-CF3 with amino acid derived ring-templates: Studies with oxazin-2-ones and oxazolidin-5-ones Journal of Chemical Research - Part S. 310-311. DOI: 10.3184/030823400103167606  0.434
2000 Adlington RM, Baldwin JE, Catterick D, Pritchard GJ, Tang LT. The synthesis of novel heterocyclic substituted α-amino acids; further exploitation of α-amino acid alkynyl ketones as reactive substrates Journal of the Chemical Society, Perkin Transactions 1. 2311-2316. DOI: 10.1039/B001825M  0.608
2000 Adlington RM, Baldwin JE, Catterick D, Pritchard GJ. A versatile synthetic route to quinoxaline, pyrazine and 1,2,4-triazine substituted α-amino acids from vicinal tricarbonyls Journal of the Chemical Society, Perkin Transactions 1. 299-302. DOI: 10.1039/A909722H  0.587
2000 Adlington RM, Baldwin JE, Catterick D, Pritchard GJ, Tang LT. The synthesis of novel heterocyclic substituted α-amino acids; further exploitation of α-amino acid alkynyl ketones Journal of the Chemical Society-Perkin Transactions 1. 303-305. DOI: 10.1039/A909720A  0.369
2000 Baldwin JE, James DA, Lee V. Preparation of 3-alkylpyridines. Formal total synthesis of haliclamines A and B Tetrahedron Letters. 41: 733-736. DOI: 10.1016/S0040-4039(99)02120-6  0.329
2000 Adlington RM, Baldwin JE, Pritchard GJ, Spencer KC. Synthesis of novel C-nucleosides with potential applications in combinatorial and parallel synthesis Tetrahedron Letters. 41: 575-578. DOI: 10.1016/S0040-4039(99)02078-X  0.589
2000 Adlington RM, Baldwin JE, Challis GL, Cox RJ, Pritchard GJ. Towards a Biomimetic Synthesis of the Marine Alkaloids Papuamine and Haliclonadiamine: Model Studies Tetrahedron. 56: 623-628. DOI: 10.1016/S0040-4020(99)01011-X  0.365
2000 Fekner T, Baldwin JE, Adlington RM, Jones TW, Prout C, Schofield CJ. Syntheses of (6S)-Cephalosporins from 6-Aminopenicillanic Acid Tetrahedron. 56: 6053-6074. DOI: 10.1016/S0040-4020(00)00486-5  0.757
1999 Adlington RM, Baldwin JE, Pritchard GJ, Williams AJ, Watkin DJ. A Biomimetic Synthesis of Lucidene Organic Letters. 1: 1937-1939. PMID 10905861 DOI: 10.1021/Ol991068Q  0.459
1999 Baldwin JE, Mayweg AV, Neumann K, Pritchard GJ. Studies toward the biomimetic synthesis of tropolone natural products via a hetero Diels-Alder reaction. Organic Letters. 1: 1933-5. PMID 10905860 DOI: 10.1021/Ol991067Y  0.403
1999 Burzlaff NI, Rutledge PJ, Clifton IJ, Hensgens CM, Pickford M, Adlington RM, Roach PL, Baldwin JE. The reaction cycle of isopenicillin N synthase observed by X-ray diffraction. Nature. 401: 721-4. PMID 10537113 DOI: 10.1038/44400  0.817
1999 Lloyd MD, Lee HJ, Harlos K, Zhang ZH, Baldwin JE, Schofield CJ, Charnock JM, Garner CD, Hara T, Terwisscha van Scheltinga AC, Valegård K, Viklund JA, Hajdu J, Andersson I, Danielsson A, et al. Studies on the active site of deacetoxycephalosporin C synthase. Journal of Molecular Biology. 287: 943-60. PMID 10222202 DOI: 10.1006/Jmbi.1999.2594  0.372
1999 Lloyd MD, Lee H, Baldwin JE, Schofield CJ, Charnock JM, Garner CD. Studies on Deacetoxycephalosporin C Synthase Biochemical Society Transactions. 27: A36-A36. DOI: 10.1042/Bst027A036C  0.323
1999 Adlington RM, Baldwin JE, Catterick D, Pritchard GJ. The synthesis of pyrimidin-4-yl substituted α-amino acids. A versatile approach from alkynyl ketones Journal of the Chemical Society-Perkin Transactions 1. 855-866. DOI: 10.1039/A806741D  0.393
1999 Baldwin JE, Vollmer HR, Lee V. Total synthesis of cytotoxic sponge alkaloids motuporamines A and B Tetrahedron Letters. 40: 5401-5404. DOI: 10.1016/S0040-4039(99)01016-3  0.34
1999 Lloyd MD, Merritt KD, Lee V, Sewell TJ, Wha-Son B, Baldwin JE, Schofield CJ, Elson SW, Baggaley KH, Nicholson NH. Product-substrate engineering by bacteria: Studies on clavaminate synthase, a trifunctional dioxygenase Tetrahedron. 55: 10201-10220. DOI: 10.1016/S0040-4020(99)00547-5  0.42
1999 Baldwin JE, Beyeler A, Cox RJ, Keats C, Pritchard GJ, Adlington RM, Watkin DJ. Reinvestigation of the dimerisation process forming isoglaucanic acid Tetrahedron. 55: 7363-7374. DOI: 10.1016/S0040-4020(99)00360-9  0.504
1999 Walter MW, Valladares MH, Adlington RM, Amicosante G, Baldwin JE, Frère JM, Galleni M, Rossolini GM, Schofield CJ. Hydroxamate inhibitors of Aeromonas hydrophila AE036 metallo-β- lactamase Bioorganic Chemistry. 27: 35-40. DOI: 10.1006/Bioo.1998.1111  0.578
1999 Baldwin JE, Claridge TDW, Culshaw AJ, Heupel FA, Lee V, Spring DR, Whitehead RC. Studies on the Biomimetic Synthesis of the Manzamine Alkaloids Chemistry - a European Journal. 5: 3154-3161. DOI: 10.1002/(Sici)1521-3765(19991105)5:11<3154::Aid-Chem3154>3.0.Co;2-7  0.555
1998 Baldwin JE, Claridge TDW, Culshaw AJ, Heupel FA, Lee V, Spring DR, Whitehead RC, Boughtflower RJ, Mutton IM, Upton RJ. Investigations into the Manzamine Alkaloid Biosynthetic Hypothesis. Angewandte Chemie (International Ed. in English). 37: 2661-2663. PMID 29711622 DOI: 10.1002/(Sici)1521-3773(19981016)37:19<2661::Aid-Anie2661>3.0.Co;2-D  0.561
1998 Valegård K, van Scheltinga AC, Lloyd MD, Hara T, Ramaswamy S, Perrakis A, Thompson A, Lee HJ, Baldwin JE, Schofield CJ, Hajdu J, Andersson I. Structure of a cephalosporin synthase. Nature. 394: 805-9. PMID 9723623 DOI: 10.1038/29575  0.505
1998 Walter MW, Adlington RM, Baldwin JE, Schofield CJ. Reaction of (Trifluoromethyl)trimethylsilane with Oxazolidin-5-ones:  Synthesis of Peptidic and Nonpeptidic Trifluoromethyl Ketones The Journal of Organic Chemistry. 63: 5179-5192. DOI: 10.1021/Jo980443+  0.673
1998 Adlington RM, Baldwin JE, Challis GL. Rate enhancement in the reduction of (2,3)-α- and (2,3)-β- methylenepenam β-sulfoxides Tetrahedron Letters. 39: 8537-8540. DOI: 10.1016/S0040-4039(98)01893-0  0.521
1998 Fekner T, Baldwin JE, Adlington RM, Schofield CJ. Unusually stable azetidinone sulfenic acids Tetrahedron Letters. 39: 6983-6986. DOI: 10.1016/S0040-4039(98)01482-8  0.609
1998 Baldwin JE, Spring DR, Whitehead RC. A novel Diels-Alder approach to hydroisoquinolines Tetrahedron Letters. 39: 5417-5420. DOI: 10.1016/S0040-4039(98)01043-0  0.525
1998 Baldwin JE, Fryer AM, Pritchard GJ, Spyvee MR, Whitehead RC, Wood ME. Concise syntheses of acromelic acid A and allo-acromelic acid A Tetrahedron Letters. 39: 707-710. DOI: 10.1016/S0040-4039(97)10641-4  0.333
1998 Baldwin JE, Spring DR, Atkinson CE, Lee V. Efficient synthesis of the sponge alkaloids cyclostellettamines A-F Tetrahedron. 54: 13655-13680. DOI: 10.1016/S0040-4020(98)00842-4  0.523
1998 Baldwin JE, Fryer AM, Pritchard GJ, Spyvee MR, Whitehead RC, Wood ME. A biomimetic approach to the pyridone rings of the acromelic acids: A concise synthesis of acromelic acid a and an approach to acromelic acid B Tetrahedron. 54: 7465-7484. DOI: 10.1016/S0040-4020(98)00377-9  0.371
1998 Kenneth Robinson J, Lee V, Claridge TD, Baldwin JE, Schofield CJ. Synthesis of (2S, 3R, 4S), (2S, 3S, 4R)-epoxyprolines and aminohydroxyprolines Tetrahedron. 54: 981-996. DOI: 10.1016/S0040-4020(97)10352-0  0.386
1998 Gibson EJ, Zhang Z, Baldwin JE, Schofield CJ. Substrate analogues and inhibition of ACC oxidase: Conversion of D- valine to iso-butanal Phytochemistry. 48: 619-624. DOI: 10.1016/S0031-9422(97)00965-5  0.425
1998 Baldwin JE, Claridge TDW, Culshaw AJ, Heupel FA, Lee V, Spring DR, Whitehead RC, Boughtflower RJ, Mutton IM, Upton RJ. Untersuchungen zur Hypothese der Manzaminalkaloid-Biosynthese Angewandte Chemie. 110: 2806-2808. DOI: 10.1002/(Sici)1521-3757(19981002)110:19<2806::Aid-Ange2806>3.0.Co;2-R  0.449
1998 Baldwin JE, Adlington RM, Crouch NP, Pereira IAC. The enzymatic synthesis of isotopically labelled penicillin Ns with isopenicillin N synthase Journal of Labelled Compounds and Radiopharmaceuticals. 41: 1145-1163. DOI: 10.1002/(Sici)1099-1344(199812)41:12<1145::Aid-Jlcr159>3.0.Co;2-2  0.517
1997 Byford MF, Baldwin JE, Shiau CY, Schofield CJ. The Mechanism of ACV Synthetase. Chemical Reviews. 97: 2631-2650. PMID 11851475 DOI: 10.1021/Cr960018L  0.38
1997 Schofield CJ, Baldwin JE, Byford MF, Clifton I, Hajdu J, Hensgens C, Roach P. Proteins of the penicillin biosynthesis pathway. Current Opinion in Structural Biology. 7: 857-64. PMID 9434907 DOI: 10.1016/S0959-440X(97)80158-3  0.666
1997 Zhang Z, Barlow JN, Baldwin JE, Schofield CJ. Metal-catalyzed oxidation and mutagenesis studies on the iron(II) binding site of 1-aminocyclopropane-1-carboxylate oxidase. Biochemistry. 36: 15999-6007. PMID 9398335 DOI: 10.1021/Bi971823C  0.396
1997 Shiau CY, Byford MF, Aplin RT, Baldwin JE, Schofield CJ. L-delta-(alpha-Aminoadipoyl)-L-cysteinyl-D-valine synthetase: thioesterification of valine is not obligatory for peptide bond formation. Biochemistry. 36: 8798-806. PMID 9220966 DOI: 10.1021/Bi962932E  0.429
1997 Roach PL, Clifton IJ, Hensgens CM, Shibata N, Schofield CJ, Hajdu J, Baldwin JE. Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation. Nature. 387: 827-30. PMID 9194566 DOI: 10.1038/42990  0.627
1997 Barlow JN, Zhang Z, John P, Baldwin JE, Schofield CJ. Inactivation of 1-aminocyclopropane-1-carboxylate oxidase involves oxidative modifications. Biochemistry. 36: 3563-9. PMID 9132007 DOI: 10.1021/Bi962521Y  0.364
1997 Sami M, Brown TJ, Roach PL, Schofield CJ, Baldwin JE. Glutamine-330 is not essential for activity in isopenicillin N synthase from Aspergillus nidulans. Febs Letters. 405: 191-4. PMID 9089289  0.387
1997 Barlow JN, Baldwin JE, Clifton IJ, Gibson E, Hensgens CM, Hajdu J, Hara T, Hassan A, John P, Lloyd MD, Roach PL, Prescott A, Robinson JK, Zhang ZH, Schofield CJ. Studies on non-haem ferrous-dependent oxygenases and oxidases. Biochemical Society Transactions. 25: 86-90. PMID 9056849 DOI: 10.1042/Bst0250086  0.562
1997 Adlington RM, Baldwin JE, MC Coull W, Pritchard GJ, Schofield CJ, Westwood NJ. An Investigation of the N-Arylsulfonylation of 2-Azetidinones Synthetic Communications. 27: 3803-3813. DOI: 10.1080/00397919708007305  0.714
1997 Uno H, Baldwin J, Churcher I, Russell A. Stereocontrolled Mukaiyama-type Aldol Reaction of Siloxypyrroles Derived from (S)-Glutamic Acid Synlett. 1997: 390-392. DOI: 10.1055/S-1997-798  0.333
1997 Baldwin JE, Chen D, Russell AT. On the synthesis of vinyl isonitriles Chemical Communications. 2389-2390. DOI: 10.1039/A706830A  0.359
1997 Thirkettle JE, Baldwin JE, Edwards J, Griffin JP, Schofield CJ. The origin of the β-lactam carbons of clavulanic acid Chemical Communications. 1025-1026. DOI: 10.1039/A701934C  0.452
1997 Adlington RM, Baldwin JE, Chen B, Cooper SL, McCoull W, Pritchard GJ, Howe TJ, Becker GW, Hermann RB, McNulty AM, Neubauer BL. Design and synthesis of novel monocyclic β-lactam inhibitors of prostate specific antigen Bioorganic and Medicinal Chemistry Letters. 7: 1689-1694. DOI: 10.1016/S0960-894X(97)00285-0  0.531
1997 Baldwin JE, Adlington RM, Crouch NP, Hill RL, Wood ME, Lloyd MD. Competing pathways in the oxidation of Z-3-ethylidine cephalosporin C by the enzyme deacetoxycephalosporin C synthase (DAOCS) Bioorganic and Medicinal Chemistry Letters. 7: 593-596. DOI: 10.1016/S0960-894X(97)00052-8  0.512
1997 Baldwin JE, Spyvee MR, Whitehead RC. A biomimetic synthesis of stizolobinic acid Tetrahedron Letters. 38: 2771-2774. DOI: 10.1016/S0040-4039(97)00467-X  0.424
1997 Crouch NP, Adlington RM, Baldwin JE, Lee MH, MacKinnon CH, Paul DR. Stereochemical course of the conversion of α-ketoisocaproate to β-hydroxyisovalerate by soluble, recombinant mammalian 4-hydroxyphenylpyruvate dioxygenase Tetrahedron. 53: 10827-10840. DOI: 10.1016/S0040-4020(97)00690-X  0.488
1997 Walter MW, Adlington RM, Baldwin JE, Schofield CJ. Synthesis of metallo-β-lactamase inhibitors Tetrahedron. 53: 7275-7290. DOI: 10.1016/S0040-4020(97)00404-3  0.6
1997 Baldwin JE, Adlington RM, Bryans JS, Lloyd MD, Sewell TJ, Schofield CJ, Baggaley KH, Cassels R. Chemo-enzymatic synthesis of bicyclic γ-lactams using clavaminic acid synthase Tetrahedron. 53: 7011-7020. DOI: 10.1016/S0040-4020(97)00399-2  0.606
1997 Crouch NP, Adlington RM, Baldwin JE, Lee MH, MacKinnon CH. A mechanistic rationalisation for the substrate specificity of recombinant mammalian 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) Tetrahedron. 53: 6993-7010. DOI: 10.1016/S0040-4020(97)00398-0  0.487
1997 Baldwin JE, Bischoff L, Claridge TD, Heupel FA, Spring DR, Whitehead RC. An approach to the manzamine alkaloids modelled on a biogenetic theory Tetrahedron. 53: 2271-2290. DOI: 10.1016/S0040-4020(96)01129-5  0.375
1996 Roach PL, Clifton IJ, Hensgens CM, Shibata N, Long AJ, Strange RW, Hasnain SS, Schofield CJ, Baldwin JE, Hajdu J. Anaerobic crystallisation of an isopenicillin N synthase.Fe(II).substrate complex demonstrated by X-ray studies. European Journal of Biochemistry / Febs. 242: 736-40. PMID 9022704 DOI: 10.1111/J.1432-1033.1996.0736R.X  0.64
1996 Lawrence CC, Sobey WJ, Field RA, Baldwin JE, Schofield CJ. Purification and initial characterization of proline 4-hydroxylase from Streptomyces griseoviridus P8648: a 2-oxoacid, ferrous-dependent dioxygenase involved in etamycin biosynthesis. The Biochemical Journal. 313: 185-91. PMID 8546682 DOI: 10.1042/Bj3130185  0.687
1996 Shibata N, Baldwin JE, Jacobs A, Wood ME. A Stereocontrolled Synthesis of Protected (2R,3R)-3-Mercaptoaspartic Acid via a β-Aspartyl Enolate Sulfenylation Synlett. 1996: 519-520. DOI: 10.1055/S-1996-5490  0.309
1996 Fekner T, Baldwin JE, Adlington RM, Schofield CJ. Syntheses of (6S,7S)- and (6S,7R)-deacetoxycephalosporanic acids from 6-aminopenicillanic acid Chemical Communications. 1989-1990. DOI: 10.1039/Cc9960001989  0.453
1996 Adlington RM, Baldwin JE, Croach NP, Lee M, MacKinnon CH, Paul DR. Stereochemistry of hydroxylation during the conversion of α-ketoisocaproate to β-hydroxyisovalerate by 4-hydroxyphenylpyruvate dioxygenase Bioorganic & Medicinal Chemistry Letters. 6: 2721-2724. DOI: 10.1016/S0960-894X(96)00489-1  0.489
1996 Shibata N, Lloyd MD, Baldwin JE, Schofield CJ. Adipoyl-6-aminopenicillanic acid is a substrate for deacetoxycephalosporin C synthase (DAOCS) Bioorganic & Medicinal Chemistry Letters. 6: 1579-1584. DOI: 10.1016/S0960-894X(96)00278-8  0.39
1996 Walter MW, Felici A, Galleni M, Soto RP, Adlington RM, Baldwin JE, Frère J, Gololobov M, Schofield CJ. Trifluoromethyl alcohol and ketone inhibitors of metallo-β-lactamases Bioorganic & Medicinal Chemistry Letters. 6: 2455-2458. DOI: 10.1016/0960-894X(96)00453-2  0.449
1996 Adlington RM, Baldwin JE, Crouch NP, Lee M, MacKinnon CH. Identification and stereochemistry of the product of 4-HPPD catalyzed oxidation of the ketoacid of methionine Bioorganic & Medicinal Chemistry Letters. 6: 2003-2006. DOI: 10.1016/0960-894X(96)00362-9  0.33
1996 Baldwin JE, Fryer AM, Spyvee MR, Whitehead RC, Wood ME. Stereocontrol in the synthesis of kainoids Tetrahedron Letters. 37: 6923-6924. DOI: 10.1016/0040-4039(96)01522-5  0.382
1996 Farthing CN, Baldwin JE, Russell AT, Schofield CJ, Spivey AC. Syntheses of (S)-β-pyrazolylalanine and (S)-quisqualic acid from a serine-derived aziridine Tetrahedron Letters. 37: 5225-5226. DOI: 10.1016/0040-4039(96)01061-1  0.655
1996 Baldwin JE, Farthing CN, Russell AT, Schofield CJ, Spivey AC. Use of (S)-N-tert-butoxycarbonylaziridine-2-carboxylate derivatives for α-amino acid synthesis Tetrahedron Letters. 37: 3761-3764. DOI: 10.1016/0040-4039(96)00676-4  0.687
1996 Shibata N, Baldwin JE, Jacobs A, Wood ME. Electrophilic sulfenylation in a stereocontrolled synthesis of protected (2R,3R)-3-mercaptoaspartic acid from L-aspartic acid Tetrahedron. 52: 12839-12852. DOI: 10.1016/0040-4020(96)00765-X  0.326
1996 Baldwin JE, Adlington RM, Marquess DG, Pitt AR, Porter MJ, Russell AT. Evidence for an insertion-homolysis mechanism for carbon-sulphur bond formation in penicillin biosynthesis; 2. Incubation and interpretation Tetrahedron. 52: 2537-2556. DOI: 10.1016/0040-4020(95)01072-6  0.639
1996 Baldwin JE, Adlington RM, Marquess DG, Pitt AR, Porter MJ, Russell AT. Evidence for an insertion-homolysis mechanism for carbon-sulphur bond formation in penicillin biosynthesis; 1. Synthesis of tripeptide probes Tetrahedron. 52: 2515-2536. DOI: 10.1016/0040-4020(95)01071-8  0.701
1995 Shiau CY, Byford MF, Baldwin JE, Schofield CJ. Molecular mechanism of the multifunctional enzyme L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine (ACV) synthetase. Biochemical Society Transactions. 23: 629S. PMID 8654814 DOI: 10.1042/Bst023629S  0.384
1995 Shiau CY, Baldwin JE, Byford MF, Sobey WJ, Schofield CJ. delta-L-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase: the order of peptide bond formation and timing of the epimerisation reaction. Febs Letters. 358: 97-100. PMID 7821439 DOI: 10.1016/0014-5793(94)01320-Z  0.412
1995 Roach PL, Clifton IJ, Fülöp V, Harlos K, Barton GJ, Hajdu J, Andersson I, Schofield CJ, Baldwin JE. Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes. Nature. 375: 700-4. PMID 7791906 DOI: 10.1038/375700A0  0.689
1995 Blackburn JM, Sutherland JD, Baldwin JE. A heuristic approach to the analysis of enzymic catalysis: reaction of delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alpha-aminobutyrate and delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-allylglycine catalyzed by isopenicillin N synthase isozymes. Biochemistry. 34: 7548-62. PMID 7779800 DOI: 10.1021/Bi00022A031  0.703
1995 Zhang Z, Schofield CJ, Baldwin JE, Thomas P, John P. Expression, purification and characterization of 1-aminocyclopropane-1-carboxylate oxidase from tomato in Escherichia coli. The Biochemical Journal. 307: 77-85. PMID 7717997 DOI: 10.1042/Bj3070077  0.421
1995 Roach PL, Schofield CJ, Baldwin JE, Clifton IJ, Hajdu J. Crystallization and preliminary X-ray diffraction studies on recombinant isopenicillin N synthase from Aspergillus nidulans. Protein Science : a Publication of the Protein Society. 4: 1007-9. PMID 7663335 DOI: 10.1002/Pro.5560040521  0.615
1995 Shiau CY, Baldwin JE, Byford MF, Schofield CJ. Delta-L-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase: isolation of L-cysteinyl-D-valine, a 'shunt' product, and implications for the order of peptide bond formation. Febs Letters. 373: 303-6. PMID 7589488 DOI: 10.1016/0014-5793(95)01045-G  0.403
1995 Tobin MB, Cole SC, Miller JR, Baldwin JE, Sutherland JD. Amino-acid substitutions in the cleavage site of acyl-coenzyme A:isopenicillin N acyltransferase from Penicillium chrysogenum: effect on proenzyme cleavage and activity. Gene. 162: 29-35. PMID 7557412 DOI: 10.1016/0378-1119(95)00369-H  0.54
1995 Baldwin JE, Davis SC, Forrest AK, Schofield CJ. Cleavage of the 5-amino-5-carboxy-2-oxapentanoyl side chain from enzymatically synthesised penicillins and cephalosporins Bioorganic and Medicinal Chemistry Letters. 5: 2507-2512. DOI: 10.1016/0960-894X(95)00436-W  0.435
1995 Baldwin JE, Adlington RM, Crouch NP, Hill RL, Laffey TG. An expedient synthesis of trisubstituted allenes Tetrahedron Letters. 36: 7925-7928. DOI: 10.1016/0040-4039(95)01643-V  0.345
1995 Walter MW, Adlington RM, Baldwin JE, Chuhan J, Schofield CJ. Reaction of ruppert’s reagent (TMS-CF3) with Oxazolidinones: Synthesis of protected α-amino trifluoromethylketones Tetrahedron Letters. 36: 7761-7764. DOI: 10.1016/0040-4039(95)01619-S  0.531
1995 Baldwin JE, Bamford SJ, Fryer AM, Wood ME. A versatile approach to acromelic acid analogues Tetrahedron Letters. 36: 4869-4872. DOI: 10.1016/0040-4039(95)00841-Y  0.391
1995 Baldwin JE, Adlington RM, Mitchell MB. Stereocontrolled enantiospecific synthesis of anticapsin Tetrahedron. 51: 5193-5206. DOI: 10.1016/0040-4020(95)98714-S  0.579
1995 Baldwin JE, Adlington RM, Gollins DW, Godfrey CR. The stereospecific synthesis of (2S,3R) 3-carboxyproline and (2S,3R) 3-aminoproline Tetrahedron. 51: 5169-5180. DOI: 10.1016/0040-4020(95)98712-Q  0.529
1995 Baldwin JE, Adlington RM, Russell AT, Smith ML. Carbon based nucleophilic ring opening of activated monocyclic β-lactams; Synthesis and stereochemical assignment of the ACE inhibitor WF-10129 Tetrahedron. 51: 4733-4762. DOI: 10.1016/0040-4020(95)00157-4  0.593
1995 Baldwin JE, Adlington RM, Crouch NP, Mellor LC, Morgan N, Smith AM, Sutherland JD. Synthesis of (2R,3S)[4-2H3] valine: Application to the study of the ring expansion of penicillin N by deacetoxycephalosporin C synthase from Streptomyces clavuligerus Tetrahedron. 51: 4089-4100. DOI: 10.1016/0040-4020(95)00126-S  0.566
1994 Baldwin JE, Claridge TD, Hulme C, Rodger A, Schofield CJ. Comments on the use of a dichromophoric circular dichroism assay for the identification of beta-turns in peptides. International Journal of Peptide and Protein Research. 43: 180-3. PMID 8200737 DOI: 10.1111/J.1399-3011.1994.Tb00520.X  0.546
1994 Tobin MB, Cole SC, Kovacevic S, Miller JR, Baldwin JE, Sutherland JD. Acyl-coenzyme A: isopenicillin N acyltransferase from Penicillium chrysogenum: effect of amino acid substitutions at Ser227, Ser230 and Ser309 on proenzyme cleavage and activity. Fems Microbiology Letters. 121: 39-46. PMID 8082826 DOI: 10.1111/J.1574-6968.1994.Tb07073.X  0.55
1994 Baldwin JE, Shiau CY, Byford MF, Schofield CJ. Substrate specificity of L-delta-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase from Cephalosporium acremonium: demonstration of the structure of several unnatural tripeptide products. The Biochemical Journal. 301: 367-72. PMID 8042979 DOI: 10.1042/Bj3010367  0.45
1994 Fujishima Y, Nordlund P, Pelosi G, Schofield CJ, Cole SJ, Baldwin JE, Hajdu J. Crystallization and preliminary X-ray diffraction studies on a recombinant isopenicillin N synthase from Cephalosporium acremonium. Journal of Molecular Biology. 242: 712-4. PMID 7932729 DOI: 10.1006/Jmbi.1994.1622  0.422
1994 Smith JJ, Zhang ZH, Schofield CJ, John P, Baldwin JE. Inactivation of 1-aminocyclopropane-1-carboxylate (ACC) oxidase Journal of Experimental Botany. 45: 521-527. DOI: 10.1093/Jxb/45.5.521  0.389
1994 Baldwin JE, MacKenzie Turner SC, Moloney MG. Enantioselective Synthesis of Novel Functionalised Prolines via [3 + 2] Cycloadditions of a Chiral Azomethine Ylid Synlett. 1994: 925-928. DOI: 10.1055/S-1994-23050  0.538
1994 Baldwin JE, Adlington RM, Crouch NP, Drake DJ, Fujishima Y, Elson SW, Baggaley KH. Investigation of the stereospecificity of clavaminic acid synthase in the desaturation of dihydroclavaminic acid to clavaminic acid Journal of the Chemical Society, Chemical Communications. 1133-1134. DOI: 10.1039/C39940001133  0.324
1994 Baldwin JE, Adlington RM, Bebbington D, T. Russell A. Asymmetric total synthesis of the individual diastereoisomers of hypoglycin A. Tetrahedron. 50: 12015-12028. DOI: 10.1039/C39920001249  0.599
1994 Morgan N, Pereira IAC, Andersson IA, Adlington RM, Baldwin JE, Cole SCJ, Crouch NP, Sutherland JD. Substrate specificity of recombinant Streptomyces clavuligerus deacetoxycephalosporin C synthase Bioorganic and Medicinal Chemistry Letters. 4: 1595-1600. DOI: 10.1016/S0960-894X(01)80573-4  0.476
1994 Baldwin JE, Spyvee MR, Whitehead RC. Biomimetic syntheses of stizolobic acid and 3-(6-carboxy-2-oxo-4-pyridyl)alanine Tetrahedron Letters. 35: 6575-6576. DOI: 10.1016/S0040-4039(00)78276-1  0.31
1994 Baldwin JE, Fujishima Y, Goh K, Schofield CJ. Enzymes of valclavam biosynthesis Tetrahedron Letters. 35: 2783-2786. DOI: 10.1016/S0040-4039(00)77032-8  0.468
1994 Baldwin JE, Goh K, Schofield CJ. Biosynthetic precursors of valclavam Tetrahedron Letters. 35: 2779-2782. DOI: 10.1016/S0040-4039(00)77031-6  0.419
1994 Baldwin JE, Chan RY, Sutherland JD. Novel stereochemical manipulations of the penicillin nucleus Tetrahedron Letters. 35: 5519-5522. DOI: 10.1016/S0040-4039(00)73540-4  0.57
1994 Baldwin JE, Field RA, Lawrence CC, Lee V, Robinson J, Schofield CJ. Substrate specificity of proline-4-hydroxylase: Chemical and enzymatic synthesis of 2S,3R,4S-epoxyproline Tetrahedron Letters. 35: 4649-4652. DOI: 10.1016/S0040-4039(00)60753-0  0.667
1994 Baldwin JE, MacKenzie Turner SC, Moloney MG. The synthesis of substituted pyrrolidines by a Samarium (II) iodide-mediated ring closure. Part 1 Tetrahedron. 50: 9411-9424. DOI: 10.1016/S0040-4020(01)85516-2  0.513
1994 Lawlor EJ, Elson SW, Holland S, Cassels R, Hodgson JE, Lloyd MD, Baldwin JE, Schofield CJ. Expression in Escherichia coli of a clavaminic acid synthase isozyme: A trifunctional oxygenase involved in clavulanic acid biosynthesis Tetrahedron. 50: 8737-8748. DOI: 10.1016/S0040-4020(01)85347-3  0.469
1994 Kuo Y, Lambein F, Mellor LC, Adlington RM, Baldwin JE. Ring-nitrogen of β-isoxazolinone-alanine is incorporated into the neurotoxin β-N-oxalyl-l-α,β-diaminopropionic acid, in callus tissue of Lathyrus sativus Phytochemistry. 37: 713-715. DOI: 10.1016/S0031-9422(00)90344-3  0.583
1994 Baldwin JE, Rudolph M. A concise approach to kainoid analogues Tetrahedron Letters. 35: 6163-6166. DOI: 10.1016/0040-4039(94)88105-7  0.371
1993 Aplin RT, Baldwin JE, Roach PL, Robinson CV, Schofield CJ. Investigations into the post-translational modification and mechanism of isopenicillin N:acyl-CoA acyltransferase using electrospray mass spectrometry. The Biochemical Journal. 294: 357-63. PMID 8396910 DOI: 10.1042/Bj2940357  0.367
1993 Aplin RT, Baldwin JE, Cole SC, Sutherland JD, Tobin MB. On the production of alpha, beta-heterodimeric acyl-coenzyme A: isopenicillin N-acyltransferase of Penicillium chrysogenum. Studies using a recombinant source. Febs Letters. 319: 166-70. PMID 8384123 DOI: 10.1016/0014-5793(93)80060-8  0.512
1993 Randall CR, Zang Y, True AE, Que L, Charnock JM, Garner CD, Fujishima Y, Schofield CJ, Baldwin JE. X-ray absorption studies of the ferrous active site of isopenicillin N synthase and related model complexes. Biochemistry. 32: 6664-73. PMID 8329393 DOI: 10.1021/Bi00077A020  0.476
1993 Tobin MB, Baldwin JE, Cole SC, Miller JR, Skatrud PL, Sutherland JD. The requirement for subunit interaction in the production of Penicillium chrysogenum acyl-coenzyme A:isopenicillin N acyltransferase in Escherichia coli. Gene. 132: 199-206. PMID 8224864 DOI: 10.1016/0378-1119(93)90196-A  0.499
1993 Baldwin JE, Adlington RM, Godfrey CRA, Gollins DW, Smith ML, Russel AT. A New Approach to the Synthesis of γ-Keto-α-Amino Acids: Synthesis of Optically Pure 5-Hydroxy-4-oxo-L-norvaline, L-HON Synlett. 1993: 51-53. DOI: 10.1055/S-1993-22345  0.553
1993 Baldwin JE, Edwards AJ, Farthing CN, Russell AT. The Wittig Reaction of Moncyclic β-Lactams Synlett. 1993: 49-50. DOI: 10.1055/S-1993-22344  0.304
1993 Baldwin JE, Adlington RM, Mitchell MB. Stereocontrolled enantiospecific synthesis of anticapsin: Revision of the configuration Journal of the Chemical Society, Chemical Communications. 1332-1335. DOI: 10.1039/C39930001332  0.519
1993 Baldwin JE, Hulme C, Schofield CJ, Edwards AJ. Synthesis of potential β-turn bicyclic dipeptide mimetics Journal of the Chemical Society, Chemical Communications. 935-936. DOI: 10.1039/C39930000935  0.607
1993 Baldwin JE, Merritt KD, Schofield CJ. Synthesis of L-ornithines stereospecifically deuterated at C-3 Tetrahedron Letters. 34: 3919-3920. DOI: 10.1016/S0040-4039(00)79263-X  0.381
1993 Baldwin JE, Claridge TDW, Kee-Chuan G, Keeping JW, Schofield CJ. Revised structures for Tü 1718B and valclavam Tetrahedron Letters. 34: 5645-5648. DOI: 10.1016/S0040-4039(00)73905-0  0.353
1993 Baldwin JE, Field RA, Lawrence CC, Merritt KD, Schofield CJ. Proline 4-hydroxylase: Stereochemical course of the reaction Tetrahedron Letters. 34: 7489-7492. DOI: 10.1016/S0040-4039(00)60161-2  0.64
1993 Baldwin JE, Byford MF, Field RA, Shiau C, Sobey WJ, Schofield CJ. Exchange of the valine 2-H in the biosynthesis of L-δ-(α-aminoadipoyl)-L-Cysteinyl-D-valine Tetrahedron. 49: 3221-3226. DOI: 10.1016/S0040-4020(01)89904-X  0.688
1993 Baldwin JE, Adlington RM, Godfrey CR, Patel VK. Stereospecific synthesis of chlamydocin Tetrahedron. 49: 7837-7856. DOI: 10.1016/S0040-4020(01)88010-8  0.41
1993 Baldwin JE, Spivey AC, Schofield CJ, Sweeney JB. Amino acid synthesis via ring opening of N-sulphonyl aziridine-2-carboxylate esters with organometallic reagents Tetrahedron. 49: 6309-6330. DOI: 10.1016/S0040-4020(01)87968-0  0.642
1993 Baldwin JE, Adlington RM, Crouch NP, Pereira IA. Incorporation of 18O-labelled water into oxygenated products produced by the enzyme deacetoxy/deacetylcephalosporin C synthase Tetrahedron. 49: 7499-7518. DOI: 10.1016/S0040-4020(01)87226-4  0.535
1993 Baldwin JE, Adlington RM, Crouch NP, Pereira IA. Evidence for epoxidase activity in deacetoxy/deacetylcephalosporin C synthase Tetrahedron. 49: 4907-4922. DOI: 10.1016/S0040-4020(01)80408-7  0.548
1993 Baldwin JE, Hulme C, Edwards AJ, Schofield CJ, Parkes KE. Synthesis of a bicyclic γ-lactam dipeptide analogue Tetrahedron Letters. 34: 1665-1668. DOI: 10.1016/0040-4039(93)85036-V  0.655
1992 Baldwin JE, Goh KC, Schofield CJ. Oxidation of deacetylcephalosporin C by deacetoxycephalosporin C/deacetylcephalosporin C synthase. The Journal of Antibiotics. 45: 1378-81. PMID 1399861 DOI: 10.7164/Antibiotics.45.1378  0.318
1992 Baldwin JE, Adlington RM, Ramcharitar SH. A Short Asymmetric Synthesis of (R,R)-(-)-Pyrenophorin Synlett. 1992: 875-877. DOI: 10.1055/S-1992-21524  0.433
1992 Baldwin JE, Lee V, Schofield CJ. Comments on the Use of Diphenyloxazinone Derivatives as Glycine Anion Templates for Amino Acid Synthesis Synlett. 1992: 249-251. DOI: 10.1055/S-1992-21332  0.438
1992 Baldwin JE, Adlington RM, Crouch NP, Heath RJ, Pereira IAC, Sutherland JD. Substrate specificity of soluble recombinant deacetoxycephalosporin C/deacetylcephalosporin C synthase Bioorganic and Medicinal Chemistry Letters. 2: 669-672. DOI: 10.1016/S0960-894X(00)80387-X  0.467
1992 Baldwin JE, Blackburn JM, Heath RJ, Sutherland JD. High-level soluble expression and purification of deacetoxycephalosporin C/deacetylcephalosporin C synthase Bioorganic and Medicinal Chemistry Letters. 2: 663-668. DOI: 10.1016/S0960-894X(00)80386-8  0.662
1992 Baldwin JE, Adlington RM, Ramcharitar SH. Intramolecular palladium-catalysed cross coupling; a direct route to γ-Oxo-α,β-unsaturated macrocycles. Tetrahedron. 48: 2957-2976. DOI: 10.1016/S0040-4020(01)90977-9  0.563
1992 Baldwin JE, Adlington RM, Aplin RT, Crouch NP, Wilkinson R. Cephalosporin C biosynthesis : On the mechanism of hydroxylation of deacetoxycephalosporin C to deacetylcephalosporin C. Tetrahedron. 48: 6853-6862. DOI: 10.1016/S0040-4020(01)89876-8  0.512
1992 Baldwin JE, Adlington RM, Bird JW, Field RA, O'Callaghan NM, Schofield CJ. Studies on the exchange of valine-oxygen during the biosynthesis of δ-(L-α-Aminoadipoyl)-L-cysteinyl-D-valine. Tetrahedron. 48: 1099-1108. DOI: 10.1016/S0040-4020(01)88205-3  0.752
1992 Baldwin JE, Moloney MG, Parsons AF. An intramolecular cobalt cyclisation for the construction of substituted pyrrolidines. Tetrahedron. 48: 9373-9384. DOI: 10.1016/S0040-4020(01)85626-X  0.583
1992 Baldwin JE, MacKenzie Turner SC, Moloney MG. The synthesis of substituted pyrrolidines by a samarium (II) iodide mediated ring closure. Tetrahedron Letters. 33: 1517-1520. DOI: 10.1016/S0040-4020(01)85516-2  0.557
1992 Baldwin JE, Lynch GP, Schofield CJ. Isopenicilin N synthase: a new mode of reactivity Tetrahedron. 48: 9085-9100. DOI: 10.1016/S0040-4020(01)82003-2  0.548
1992 Baldwin JE, Adlington RM, Ramcharitar SH. Free radical macrocyclisation via propiolate esters. Tetrahedron. 48: 3413-3428. DOI: 10.1016/0040-4020(92)85015-7  0.574
1992 Baldwin JE, Adlington RM, Singh R. Carbocyclic ring expansion reactions via free radical pathways - part III Tetrahedron. 48: 3385-3412. DOI: 10.1016/0040-4020(92)85014-6  0.549
1991 Baldwin JE, Bird JW, Field RA, O'Callaghan NM, Schofield CJ, Willis AC. Isolation and partial characterisation of ACV synthetase from Cephalosporium acremonium and Streptomyces clavuligerus. Evidence for the presence of phosphopantothenate in ACV synthetase. The Journal of Antibiotics. 44: 241-8. PMID 2010361 DOI: 10.7164/Antibiotics.44.241  0.712
1991 Baldwin JE, Martin SL, Sutherland JD. Site-specific forced misincorporation mutagenesis using modified T7 DNA polymerase. Protein Engineering. 4: 579-84. PMID 1891465 DOI: 10.1093/protein/4.5.579  0.451
1991 Baldwin JE, O'Neil IA, Russell AT. Isonitrin A: Revision of the Structure and Total Synthesis in Racemic Form Synlett. 1991: 551-552. DOI: 10.1055/S-1991-20792  0.343
1991 Baldwin JE, Adlington RM, Crouch NP, Keeping JW, Leppard SW, Pitlik J, Schofield CJ, Sobey WJ, Wood ME. Studies on the mechanism of deacetoxy-deacetylcephalosporin C synthase using cyclopropyl substituted cephalosporin probes Journal of the Chemical Society, Chemical Communications. 768-770. DOI: 10.1039/C39910000768  0.526
1991 Baldwin JE, Claridge TD, Derome AE, Schofield CJ, Smith BD. 11B NMR studies of an aryl boronic acid bound to chymotrypsin and subtilisin Bioorganic & Medicinal Chemistry Letters. 1: 9-12. DOI: 10.1016/S0960-894X(01)81080-5  0.564
1991 Aplin RT, Baldwin JE, Pichon C, Roessner CA, Ian Scott A, Schofield CJ, Stolowich NJ, Warren MJ. Observation of enzyme bound intermediates in the biosynthesis of preuroporphyrinogen by PBG deaminase Bioorganic & Medicinal Chemistry Letters. 1: 503-506. DOI: 10.1016/S0960-894X(01)80453-4  0.346
1991 Baldwin JE, Goh KC, Wood ME, Schofield CJ, Cooper RDG, Huffman GW. The role of sulphur in cephalosporin biosynthesis Bioorganic and Medicinal Chemistry Letters. 1: 421-424. DOI: 10.1016/S0960-894X(00)80269-3  0.362
1991 Baldwin JE, Moloney MG, Bo Shim S. ()-pyroglutamic acid as a chiral starting material for asymmetric synthesis Tetrahedron Letters. 32: 1379-1380. DOI: 10.1016/S0040-4039(00)79672-9  0.61
1991 Baldwin JE, Bradley M, Turner NJ, Adlington RM, Pitt AR, Derome AE. Enzymic conversion of deuterated analogues of δ--α-aminoadipoyl--cysteinyl--allylglycine, an unnatural substrate for isopenicilin n synthase: A unified theory of second ring closure. Tetrahedron. 47: 8223-8242. DOI: 10.1016/S0040-4020(01)91016-6  0.608
1991 Baldwin JE, Bradley M, Turner NJ, Adlington RM, Pitt AR, Sheridan H. Synthesis of δ-L-α-aminoadipoyl-L-cysteinyl-D-allylglycine, and eight deuterated analogues, substrates for the investigation of the mechanism of action of isopenicillin n synthase Tetrahedron. 47: 8203-8222. DOI: 10.1016/S0040-4020(01)91015-4  0.811
1991 Baldwin J, Bradley M, Adlington R, Norris W, Turner N. Further evidence for the involvement of a monocyclic β-lactam in the enzymatic conversion of δ-L-α-aminoadipoyl-L-cysteinyl-D-valine into isopenicillin N. Tetrahedron. 47: 457-480. DOI: 10.1016/S0040-4020(01)90503-4  0.39
1991 Baldwin JE, Bradley M, Abbott SD, Adlington RM. New penicillins from isopenicillin N synthase. Tetrahedron. 47: 5309-5328. DOI: 10.1016/S0040-4020(01)87142-8  0.58
1991 Baldwin JE, Adlington RM, Mitchell MB, Robertson J. Intramolecular SH2′ macrocyclisations Tetrahedron. 47: 5901-5918. DOI: 10.1016/S0040-4020(01)86541-8  0.71
1991 Baldwin JE, Adlington RM, Godfrey CR, Gollins DW, Schofield CJ. The Stereospecific Synthesis of alahopcin Tetrahedron. 47: 5835-5840. DOI: 10.1016/S0040-4020(01)86533-9  0.557
1991 Baldwin JE, Blackburn JM, Sutherland JD, Wright MC. High-level soluble expression of isopenicillin N synthase isozymes in E. coli Tetrahedron. 47: 5991-6002. DOI: 10.1016/S0040-4020(01)86491-7  0.661
1991 Baldwin JE, Adlington RM, Bryans JS, Bringhen AO, Coates JB, Crouch NP, Lloyd MD, Schofield CJ, Elson SW, Baggaley KH, Cassels R, Nicholson N. Isolation of dihydroclavaminic acid, an intermediate in the biosynthesis of clavulanic acid Tetrahedron. 47: 4089-4100. DOI: 10.1016/S0040-4020(01)86446-2  0.563
1991 Baldwin JE, Adlington RM, Robertson J. Carbocyclic ring expansion reactions via radical chain processes. Part II. Tetrahedron. 47: 6795-6812. DOI: 10.1016/S0040-4020(01)82331-0  0.715
1991 Baldwin JE, Jesudason CD, Moloney MG, Morgan DR, Pratt AJ. The synthesis of substituted aryl diazirines. A bifunctional reagent suitable for application to photoaffinity labelling studies Tetrahedron. 47: 5603-5614. DOI: 10.1016/S0040-4020(01)80991-1  0.581
1991 Baldwin JE, Adlington RM, Crouch NP, Schofield CJ, Turner NJ, Aplin RT. Cephalosporin biosynthesis: A branched pathway sensitive to an isotope effect Tetrahedron. 47: 9881-9900. DOI: 10.1016/S0040-4020(01)80725-0  0.626
1991 Fujishima Y, Schofield C, Baldwin J, Charnock J, Garner C. Recent physical and mechanistic studies on isopenicillin N synthase Journal of Inorganic Biochemistry. 43: 564. DOI: 10.1016/0162-0134(91)84539-L  0.329
1991 Baldwin JE, Adlington RM, Kang TW. Direct Ring Expansion of Penicillins to 3-Exomethylene Cephalosporins Tetrahedron Letters. 32: 7093-7096. DOI: 10.1016/0040-4039(91)85049-B  0.554
1991 Baldwin JE, Moloney MG, Parsons AF. Enantioselective synthesis of kainoid analogues by cobalt-mediated cyclisations Tetrahedron. 47: 155-172. DOI: 10.1016/0040-4020(91)80018-W  0.614
1990 Aplin RT, Baldwin JE, Schofield CJ, Waley SG. Use of electrospray mass spectrometry to directly observe an acyl enzyme intermediate in beta-lactamase catalysis. Febs Letters. 277: 212-4. PMID 2269358 DOI: 10.1016/0014-5793(90)80847-C  0.35
1990 Baldwin JE, Bird JW, Field RA, O'Callaghan NM, Schofield CJ. Isolation and partial characterisation of ACV synthetase from Cephalosporium acremonium and Streptomyces clavuligerus. The Journal of Antibiotics. 43: 1055-7. PMID 2211358 DOI: 10.7164/Antibiotics.43.1055  0.712
1990 Aplin RT, Baldwin JE, Fujishima Y, Schofield CJ, Green BN, Jarvis SA. Molecular weight analysis of isopenicillin N synthase by electrospray mass spectrometry. Febs Letters. 264: 215-7. PMID 2192915 DOI: 10.1016/0014-5793(90)80251-D  0.322
1990 Baldwin JE, Blackburn JM, Schofield CJ, Sutherland JD. High level expression in Escherichia coli of a fungal gene under the control of strong promoters. Fems Microbiology Letters. 56: 45-51. PMID 2185127 DOI: 10.1016/0378-1097(90)90122-7  0.489
1990 Whiteman PA, Abraham EP, Baldwin JE, Fleming MD, Schofield CJ, Sutherland JD, Willis AC. Acyl coenzyme A: 6-aminopenicillanic acid acyltransferase from Penicillium chrysogenum and Aspergillus nidulans. Febs Letters. 262: 342-4. PMID 2110531 DOI: 10.1016/0014-5793(90)80224-7  0.598
1990 Baldwin JE, Blackburn JM, Schofield CJ. The enzymatic synthesis of 3-aceto-penams using isopenicillin n synthase Biocatalysis and Biotransformation. 3: 129-136. DOI: 10.3109/10242429008992055  0.481
1990 Baldwin JE, Adlington RM, Mitchell MB, Robertson J. Radical reactions in synthesis: Intramolecular SH2′ macrocyclisations Journal of the Chemical Society, Chemical Communications. 1574-1575. DOI: 10.1039/C39900001574  0.696
1990 Baldwin JE, Bradley M, Abbott SD, Adlington RM. Formation of novel unsaturated side chain penicillins with isopenicillin N synthase Journal of the Chemical Society, Chemical Communications. 1008-1010. DOI: 10.1039/C39900001008  0.409
1990 Baldwin JE, Spivey AC, Schofield CJ. Cyclic sulphamidates: New synthetic precursors for β-functionalised α-amino acids Tetrahedron: Asymmetry. 1: 881-884. DOI: 10.1016/S0957-4166(00)82279-X  0.645
1990 Baldwin JE, Schofield CJ, Smith BD. Side chain specificity in the pnzymatic synthesis of eenicillins Tetrahedron. 46: 3019-3028. DOI: 10.1016/S0040-4020(01)88393-9  0.592
1990 Baldwin JE, Adlington RM, Schofield CJ, Ting H. Penicillin biosynthesis: dependence of substrate stereochemistry on the mode of second ring closure Tetrahedron. 46: 6145-6154. DOI: 10.1016/S0040-4020(01)87936-9  0.64
1990 Baldwin JE, Moloney MG, Parsons AF. Enantioselective kainoid synthesis by cobalt-mediated cyclisation of an amino acid derivative Tetrahedron. 46: 7263-7282. DOI: 10.1016/S0040-4020(01)87906-0  0.62
1990 Baldwin JE, McConnaughie AW, Moloney MG, Pratt AJ, Bo Shin S. New photolabile phosphate protecting group Tetrahedron. 46: 6879-6884. DOI: 10.1016/S0040-4020(01)87875-3  0.526
1990 Baldwin JE, Adlington RM, Gollins DW, Schofield CJ. Stereospecific synthesis of dealanylalahopcin Tetrahedron. 46: 4733-4748. DOI: 10.1016/S0040-4020(01)85592-7  0.555
1990 Baldwin JE, Lowe C, Schofield CJ. The synthesis of potential γ-lactam antibiotics containing a cycloserine nucleus Tetrahedron Letters. 31: 2211-2212. DOI: 10.1016/0040-4039(90)80111-X  0.524
1990 BALDWIN JE, ADLINGTON RM, GOLLINS DW, SCHOFIELD CJ. ChemInform Abstract: Enantiospecific Synthesis of Dealanylalahopcin (I). Cheminform. 21. DOI: 10.1002/chin.199045327  0.441
1990 BALDWIN JE, ADLINGTON RM, GOLLINS DW, SCHOFIELD CJ. ChemInform Abstract: Stereospecific Synthesis of Dealanylalahopcin. Cheminform. 21. DOI: 10.1002/chin.199044307  0.447
1990 BALDWIN JE, SCHOFIELD CJ, SMITH BD. ChemInform Abstract: Side Chain Specificity in the Enzymatic Synthesis of Penicillins. Cheminform. 21. DOI: 10.1002/chin.199036314  0.406
1990 BALDWIN JE, ADLINGTON RM, O'NEIL IA, SCHOFIELD C, SPIVEY AC, SWEENEY JB. ChemInform Abstract: The Ring Opening of Aziridine-2-carboxylate Esters with Organometallic Reagents. Cheminform. 21. DOI: 10.1002/chin.199021298  0.618
1990 BALDWIN JE, MIRANDA T, MOLONEY M, HOKELEK T. ChemInform Abstract: Amino Acid Synthesis Using (L)-Pyroglutamic Acid as a Chiral Starting Material. Cheminform. 21. DOI: 10.1002/chin.199015267  0.542
1990 BALDWIN JE, FREEMAN RT, SCHOFIELD C. ChemInform Abstract: Synthesis of a Novel Bicyclic γ-Lactam Analogue of the 1-Oxapenams. Cheminform. 21. DOI: 10.1002/chin.199009173  0.463
1990 BALDWIN JE, MOLONEY MG, NORTH M. ChemInform Abstract: Non-Proteinogenic Amino Acid Synthesis: Synthesis of β,γ-Unsaturated α-Amino Acids from Aspartic Acid. Cheminform. 21. DOI: 10.1002/chin.199005269  0.62
1990 BALDWIN JE, MOLONEY MG, NORTH M. ChemInform Abstract: Non-Proteinogenic Amino Acid Synthesis. The β-Anion Derived from Aspartic Acid, and Its Application to α-Amino Acid Synthesis. Cheminform. 21. DOI: 10.1002/chin.199005268  0.544
1989 Baldwin JE, Coates JB, Halpern JB, Moloney MG, Pratt AJ. Photoaffinity labelling of isopenicillin N synthetase by laser-flash photolysis. The Biochemical Journal. 261: 197-204. PMID 2775205 DOI: 10.1042/Bj2610197  0.571
1989 Baldwin JE, Adlington RM, O'Neil IA, Schofield C, Spivey AC, Sweeney JB. The ring opening of aziridine-2-carboxylate esters with organometallic reagents Journal of the Chemical Society, Chemical Communications. 1852-1854. DOI: 10.1039/C39890001852  0.656
1989 Baldwin JE, Adlington RM, Bird JW, Schofield CJ. The fate of valine-oxygen during penicillin biosynthesis Journal of the Chemical Society - Series Chemical Communications. 1615-1616. DOI: 10.1039/C39890001615  0.537
1989 Baldwin JE, Adlington RM, Schofield CJ, Sobey WJ, Wood ME. The role of α-ketoglutarate in cephalosporin biosynthesis Journal of the Chemical Society, Chemical Communications. 1012-1015. DOI: 10.1039/C39890001012  0.547
1989 Baldwin JE, Blackburn JM, Sako M, Schofield CJ. Formation of a novel bicyclic γ-lactam with isopenicillin N synthase Journal of the Chemical Society, Chemical Communications. 970-972. DOI: 10.1039/C39890000970  0.465
1989 Baldwin JE, Freeman RT, Schofield C. Synthesis of a novel bicyclic γ-lactam analogue of the 1-oxapenams Tetrahedron Letters. 30: 4019-4020. DOI: 10.1016/S0040-4039(00)99312-2  0.517
1989 Baldwin JE, Yamaguchi Y. A facile route to vinyl isocyanides Tetrahedron Letters. 30: 3335-3338. DOI: 10.1016/S0040-4039(00)99237-2  0.362
1989 Baldwin JE, Miranda T, Moloney M, Hokelek T. Amino acid synthesis using (L)-pyroglutamic acid as a chiral starting material Tetrahedron. 45: 7459-7468. DOI: 10.1016/S0040-4020(01)89208-5  0.623
1989 Baldwin JE, Freeman RT, Lowe C, Schofield CJ, Lee E. A γ-lactam analogue of the penems possessing antibacterial activity Tetrahedron. 45: 4537-4550. DOI: 10.1016/S0040-4020(01)89088-8  0.516
1989 Baldwin JE, Moloney MG, North M. Non-proteinogenic amino acid synthesis: Synthesis of β,γ-unsaturated α-amino acids from asparic acid Tetrahedron. 45: 6319-6330. DOI: 10.1016/S0040-4020(01)85141-3  0.59
1989 Baldwin JE, Moloney MG, North M. Non-proteinogenic amino acid synthesis. The β-anion derived from aspartic acid, and its application to α-amino acid synthesis. Tetrahedron. 45: 6309-6318. DOI: 10.1016/S0040-4020(01)85140-1  0.606
1989 Baldwin JE, Adlington RM, Moss N. Synthetic Approaches to 2-Methoxycysteine containing Peptides. The conversion of [(5S)-5-amino-5-carboxy-2-oxapentanoyl]-2-methoxy-(2S)-cysteinyl-(2R)-valine into 10-Oxa-6α-methoxyisopenicillin N by the Enzyme Isopenicillin N Synthase Tetrahedron. 45: 2841-2856. DOI: 10.1016/S0040-4020(01)80113-7  0.523
1989 Baldwin JE, North M, Flinn A, Moloney MG. Synthesis of nonproteinogenic amino acids part 3: conversion of glutamic acid into γ,δ-unsaturated α-amino acids Tetrahedron. 45: 1465-1474. DOI: 10.1016/0040-4020(89)80145-0  0.585
1989 Baldwin JE, North M, Flinn A, Moloney MG. Synthesis of nonproteinogenic amino acids part 2: preparation of a synthetic equivalent of the γ anion synthon for asymmetric amino acid synthesis Tetrahedron. 45: 1453-1464. DOI: 10.1016/0040-4020(89)80144-9  0.604
1989 Baldwin JE, Adlington RM, Robertson J. Carbocyclic ring expansion reactiuon VIA radical chain processes Tetrahedron. 45: 909-922. DOI: 10.1016/0040-4020(89)80003-1  0.687
1989 Baldwin JE, Adlington RM, Russell MA, Schofield CJ, Wood ME. Syntheses of [2-13C] and [1,2-13C] labelled α-ketoglutaric acid Journal of Labelled Compounds and Radiopharmaceuticals. 27: 1091-1099. DOI: 10.1002/Jlcr.2580270914  0.598
1989 BALDWIN JE, FREEMAN RT, LOWE C, SCHOFIELD CJ, LEE E. ChemInform Abstract: A γ-Lactam Analogue of the Penems Possessing Antibacterial Activity. Cheminform. 20. DOI: 10.1002/chin.198949310  0.374
1989 BALDWIN JE, ADLINGTON RM, KANG TW, KING LG, PATEL VK. ChemInform Abstract: Desulfurization of Penicillins with Triphenylstannane. Cheminform. 20. DOI: 10.1002/chin.198942085  0.447
1989 BALDWIN JE, ADLINGTON RM, MOSS N. ChemInform Abstract: Synthetic Approaches to 2-Methoxycysteine-Containing Peptides. The Conversion of ((5S)-5-Amino-5-carboxy-2-oxapentanoyl)-2-methoxy-(2S)-cysteinyl-(2R)-valine into 10-Oxa-6α-methoxyisopenicillin N by the Enzyme Isopenicillin N Synthase Cheminform. 20. DOI: 10.1002/chin.198936349  0.514
1989 BALDWIN JE, MOLONEY MG, NORTH M. ChemInform Abstract: Asymmetric Amino Acid Synthesis: Preparation of the β Anion Derived from Aspartic Acid. Cheminform. 20. DOI: 10.1002/chin.198929264  0.623
1989 BALDWIN JE, NORTH M, FLINN A, MOLONEY MG. ChemInform Abstract: Synthesis of Nonproteinogenic Amino Acids. Part 3. Conversion of Glutamic Acid into γ,δ-Unsaturated α-Amino Acids. Cheminform. 20. DOI: 10.1002/chin.198928304  0.522
1989 BALDWIN JE, NORTH M, FLINN A, MOLONEY MG. ChemInform Abstract: Synthesis of Nonproteinogenic Amino Acids. Part 2. Preparation of a Synthetic Equivalent of the γ-Anion Synthon for Asymmetric Amino Acid Synthesis. Cheminform. 20. DOI: 10.1002/chin.198928303  0.549
1989 BALDWIN JE, ADLINGTON RM, KANG TW, LEE E, SCHOFIELD CJ. ChemInform Abstract: The Ring Expansion of Penams to Cephams: A Possible Biomimetic Process. Cheminform. 20. DOI: 10.1002/chin.198904315  0.351
1989 BALDWIN JE, NORRIS WJ, FREEMAN RT, BRADLEY M, ADLINGTON RM, LONG-FOX S, SCHOFIELD CJ. ChemInform Abstract: γ-Lactam Formation from Tripeptides with Isopenicillin N Synthase. Cheminform. 20. DOI: 10.1002/chin.198903315  0.589
1989 BALDWIN JE, ADLINGTON RM, LOWE C, O'NEIL IA, SANDERS GL, SCHOFIELD CJ, SWEENEY JB. ChemInform Abstract: Reactions of a Glycidyl Radical Equivalent with 2-Functionalized Allylstannanes. Cheminform. 20. DOI: 10.1002/chin.198903281  0.356
1988 Baldwin JE, Adlington RM, Crouch NP, Coates JB, Keeping JW, Schofield CJ, Shuttleworth WA, Sutherland JD. Substrate specificity of cloned deacetoxycephalosporin C/deacetylcephalosporin C synthetase. The Journal of Antibiotics. 41: 1694-5. PMID 3198501 DOI: 10.7164/Antibiotics.41.1694  0.653
1988 Baldwin JE, Adlington RM, King LG, Parisi MF, Sobey WJ, Sutherland JD, Ting HH. Penicillin biosynthesis: Stereochemistry of desaturative and hydroxylative pathways from L-α-aminoadipoyl-L-cysteinyl-D-isodehydrovaline with isopenicillin N synthase Journal of the Chemical Society, Chemical Communications. 1635-1637. DOI: 10.1039/C39880001635  0.534
1988 Baldwin JE, Norris WJ, Freeman RT, Bradley M, Adlington RM, Long-Fox S, Schofield CJ. γ-lactam formation from tripeptides with isopenicillin N synthase Journal of the Chemical Society, Chemical Transactions. 1128-1130. DOI: 10.1039/C39880001128  0.696
1988 Baldwin JE, Adlington RM, Lowe C, O'Neil IA, Sanders GL, Schofield CJ, Sweeney JB. Reactions of a glycidyl radical equivalent with 2-functionalised allyl stannanes Journal of the Chemical Society, Chemical Communications. 1030-1031. DOI: 10.1039/C39880001030  0.639
1988 Baldwin JE, North M, Flinn A, Moloney MG. Stereospecific amino acid synthesis; preparation of the γ-anion derived from glutamic acid Journal of the Chemical Society, Chemical Communications. 828-829. DOI: 10.1039/C39880000828  0.617
1988 Baldwin JE, Adlington RM, Lajoie GA, Lowe C, Baird PD, Prout K. On the biosynthesis of ethylene: Further evidence for stepwise enzymatic cyclopropane ring cleavage Journal of the Chemical Society, Chemical Communications. 775-777. DOI: 10.1039/C39880000775  0.474
1988 Baldwin JE, Adlington RM, Robinson NG. Enantiospecific synthesis of -(3; and 3)-(β--ribofuranosyl)-pyroglutamic acids: Possible intermediates in C-nucleoside biosynthesis Tetrahedron Letters. 29: 375-378. DOI: 10.1016/S0040-4039(00)80100-8  0.606
1988 Baldwin JE, Adlington RM, Crouch NP, Schofield CJ. The enzymatic conversion of exomethylene cephalosporin c into deacetyl cephalosporin c and the role of molecular oxygen in cephalosporin c biosynthesis Tetrahedron. 44: 643-650. DOI: 10.1016/S0040-4020(01)85852-X  0.58
1988 Baldwin JE, North M, Flinn A. Synthesis and rearangement of homoserine derivatives Tetrahedron. 44: 637-642. DOI: 10.1016/S0040-4020(01)85851-8  0.393
1988 Baldwin JE, Killin SJ, Adlington RM, Spiegel U. Synthesis of n-benzyloxycarbonyl-l-α-aminoadipic acid, α-benzyl ester Tetrahedron. 44: 2633-2636. DOI: 10.1016/S0040-4020(01)81715-4  0.605
1988 Baldwin JE, Adlington RM, Kang TW, Lee E, Schofield CJ. The ring expansion of penama to cephams: a possible biomimetic process Tetrahedron. 44: 5953-5957. DOI: 10.1016/S0040-4020(01)81453-8  0.599
1988 BALDWIN JE, NORTH M, FLINN A, MOLONEY MG. ChemInform Abstract: Stereospecific Amino Acid Synthesis. Preparation of the γ-Anion Derived from Glutamic Acid. Cheminform. 19. DOI: 10.1002/chin.198846307  0.613
1988 BALDWIN JE, ADLINGTON RM, ROBINSON NG. ChemInform Abstract: Enantiospecific Synthesis of L-(3R and 3S)-(β-D-Ribofuranosyl)pyroglutamic Acids: Possible Intermediates in C-Nucleoside Biosynthesis. Cheminform. 19. DOI: 10.1002/chin.198824357  0.556
1988 BALDWIN JE, ADLINGTON RM, CROUCH NP, SCHOFIELD CJ. ChemInform Abstract: The Enzymatic Conversion of Exomethylene Cephalosporin C into Deacetyl Cephalosporin C and the Role of Molecular Oxygen in Cephalosporin C Biosynthesis. Cheminform. 19. DOI: 10.1002/chin.198821319  0.334
1988 BALDWIN JE, NORTH M, FLINN A. ChemInform Abstract: Synthesis and Rearrangement of Homoserine Derivatives. Cheminform. 19. DOI: 10.1002/chin.198821300  0.489
1987 Baldwin JE, Adlington RM, Coates JB, Crabbe MJ, Crouch NP, Keeping JW, Knight GC, Schofield CJ, Ting HH, Vallejo CA. Purification and initial characterization of an enzyme with deacetoxycephalosporin C synthetase and hydroxylase activities. The Biochemical Journal. 245: 831-41. PMID 3663194 DOI: 10.1042/Bj2450831  0.642
1987 Baldwin JE, Crabbe MJ. A spectrophotometric assay for deacetoxycephalosporin C synthase. Febs Letters. 214: 357-61. PMID 3569531 DOI: 10.1016/0014-5793(87)80087-X  0.318
1987 Baldwin JE, Killin SJ, Pratt AJ, Sutherland JD, Turner NJ, Crabbe MJ, Abraham EP, Willis AC. Purification and characterization of cloned isopenicillin N synthetase. The Journal of Antibiotics. 40: 652-9. PMID 3301770 DOI: 10.7164/Antibiotics.40.652  0.504
1987 Baldwin JE, Adlington RM, Coates JB, Crabbe MJC, Keeping JW, Knight GC, Nomoto T, Schofield CJ, Ting HH. Enzymatic ring expansion of penicillins to cephalosporins: Side chain specificity Journal of the Chemical Society, Chemical Communications. 374-375. DOI: 10.1039/C39870000374  0.608
1987 Baldwin JE, Adlington RM, Robinson NG. Nucleophilic ring opening of aziridine-2-carboxylates with Wittig reagents; an enantioefficient synthesis of unsaturated amino acids Journal of the Chemical Society, Chemical Communications. 153-155. DOI: 10.1039/C39870000153  0.613
1987 Ziegler CB, Harris SM, Baldwin JE. 1,4-Dehydrobromination of 1-bromo-1,2,3-butatrienes: an efficient synthesis of 1,4-disubstituted 1,3-diynes The Journal of Organic Chemistry. 52: 443-446. DOI: 10.1021/Jo00379A025  0.345
1987 Baldwin JE, Ng SC, Pratt AJ. Synthesis of phenoxyacetyl-N-sulphonyl cycloserine Tetrahedron Letters. 28: 4319-4320. DOI: 10.1016/S0040-4039(00)96496-7  0.378
1987 Baldwin JE, Dyer RL, Ng SC, Pratt AJ, Russell MA. Application of E. Coli aspartate transaminase to amino acid synthesis Tetrahedron Letters. 28: 3745-3746. DOI: 10.1016/S0040-4039(00)96374-3  0.377
1987 Baldwin J, North M, Flinn A. A convenient new synthesis of homoserine lactone Tetrahedron Letters. 28: 3167-3168. DOI: 10.1016/S0040-4039(00)96313-5  0.446
1987 Baldwin J, Nga S, Pratta A, Russella M, Dyerb R. Enzymic synthesis of isotopically labelled L-tyrosine Tetrahedron Letters. 28: 2303-2304. DOI: 10.1016/S0040-4039(00)96109-4  0.379
1987 Baldwin J, Flinn A. Use of L-aspartic acid β-semialdehyde in the synthesis of more complex non protein amino acids Tetrahedron Letters. 28: 3605-3608. DOI: 10.1016/S0040-4039(00)95547-3  0.381
1987 Baldwin JE, Adlington RM, Crabbe M, Knight G, Nomoto T, Schofield CJ, Ting H. The emzymatic ring expansion of penicillins to cephalosporins : side chain specificity Tetrahedron. 43: 3009-3014. DOI: 10.1016/S0040-4020(01)86840-X  0.633
1987 Baldwin JE, Adlington RM, C. Crabbe M, Nomoto T, Schofield CJ. An efficient substitute for the α-amimoadipoyl moiety of δ-(-α-aminloadipoytl)--cisteintl--valine in the emzymatic synthesis of penicillins Tetrahedron. 43: 4217-4220. DOI: 10.1016/S0040-4020(01)83463-3  0.672
1987 Baldwin JE, Pratt AJ, Moloney MG. The synthesis of aryl substituted analogues of phenoxyacetyl-L-cysteinyl-D-valine and phenylacetyl-L-cysteinyl-D-valine. Application to the photoaffinity labeling of isopenicillin N synthetase Tetrahedron. 43: 2565-2575. DOI: 10.1016/S0040-4020(01)81664-1  0.592
1987 BALDWIN JE, ADLINGTON RM, COATES JB, CRABBE MJC, KEEPING JW, KNIGHT GC, NOMOTO T, SCHOFIELD CJ, TING H. ChemInform Abstract: Enzymatic Ring Expansion of Penicillins to Cephalosporins: Side Chain Specificity. Cheminform. 18. DOI: 10.1002/chin.198741390  0.55
1987 BALDWIN JE, PRATT AJ, MOLONEY MG. ChemInform Abstract: The Synthesis of Aryl Substituted Analogues of Phenoxyacetyl-L-cysteinyl-D-valine and Phenylacetyl-L-cysteinyl-D-valine. Application to the Photoaffinity Labeling of Isopenicillin N Synthetase. Cheminform. 18. DOI: 10.1002/chin.198741377  0.537
1987 BALDWIN JE, ADLINGTON RM, ROBINSON NG. ChemInform Abstract: Nucleophilic Ring Opening of Aziridine-2-carboxylates with Wittig Reagents. An Enantioefficient Synthesis of Unsaturated Amino Acids. Cheminform. 18. DOI: 10.1002/chin.198732313  0.555
1986 Baldwin JE, Adlington RM, Birch DJ, Crawford JA, Sweeney JB. Radical reactions in synthesis: Carbon-carbon bond formation from 2-substituted allyl trialkyl stannanes Journal of the Chemical Society, Chemical Communications. 1339-1340. DOI: 10.1039/C39860001339  0.559
1986 Baldwin JE, Adlington RM, Flitsch SL, Ting HH, Turner NJ. Penicillin biosynthesis: The origin of hydroxy groups in β-lactams derived from unsaturated substrates Journal of the Chemical Society, Chemical Communications. 1305-1308. DOI: 10.1039/C39860001305  0.652
1986 Baldwin JE, Adlington RM, Basak A, Flitsch SL, Forrest AK, Ting HH. Penicillin biosynthesis: Structure-reactivity profile of unsaturated substrates for isopenicillin N synthetase Journal of the Chemical Society, Chemical Communications. 273-275. DOI: 10.1039/C39860000273  0.744
1986 Baldwin JE, Adlington RM, Sweeney JB. Improved synthesis of α-Methylene-γ-lactones via organotin reagents Tetrahedron Letters. 27: 5423-5424. DOI: 10.1016/S0040-4039(00)85228-4  0.53
1986 Baldwin JE, Lowe C, Schofield CJ, Lee E. A γ-lactam analogue of penems possessing antibacterial activity Tetrahedron Letters. 27: 3461-3464. DOI: 10.1016/S0040-4039(00)84822-4  0.414
1986 Baldwin JE, Lee E. Synthesis of bicyclic γ-lactams via oxazolidinones Tetrahedron. 42: 6551-6554. DOI: 10.1016/S0040-4020(01)88118-7  0.421
1986 Baldwin JE, Adlington RM, Jain AU, Kolhe JN, Perry MW. Applications of the thermal ene reaction of aldehyde -butyl- and phenyl- hydrazones Tetrahedron. 42: 4247-4252. DOI: 10.1016/S0040-4020(01)87649-3  0.576
1986 Baldwin JE, Adlington RM, Bottaro JC, Kolhe JN, Newington IM, Perry MW. Azo anions in synthesis Tetrahedron. 42: 4235-4246. DOI: 10.1016/S0040-4020(01)87648-1  0.558
1986 Baldwin JE, Adlington RM, Bottaro JC, Kolhe JN, Perry MW, Jain AU. Azo anions in systhesis. pt 1. t-butylhydrazones as acyl-anion equivalents Tetrahedron. 42: 4223-4234. DOI: 10.1016/S0040-4020(01)87647-X  0.577
1986 Baldwin JE, Swanson AG, Cha JK, Murphy JA. Preparation and pyrolysis of substituted ethanoanthracenes - a general synthesis of 2,3-disubstituted anthracenes Tetrahedron. 42: 3943-3956. DOI: 10.1016/S0040-4020(01)87549-9  0.352
1986 Baldwin JE, Otsuka M, Wallace PM. Synthetic studies on tabtoxin. Synthesis of a naturally occuring inhibitor of glutamine synthetase, tabtoxinine-β-lactam, and analogues Tetrahedron. 42: 3097-3110. DOI: 10.1016/S0040-4020(01)87377-4  0.346
1986 Baldwin JE, Adlington RM, Jones RH, Schofield CJ, Zaracostas C, Greengrass CW. γ-Lactam analogues of carbapenicillanic acids Tetrahedron. 42: 4879-4888. DOI: 10.1016/S0040-4020(01)82070-6  0.642
1986 Baldwin JE, Adlington RM, Parisi MF, Ting H. The synthesis and antimicrobial activity of (1,2)-1-hydroxy-2-[(s)-valylamino]cyclobutane-1-acetic acid (1) and (1, 2)-1-hydroxy-2-aminocyclobutane-1-acetic acid (2) Tetrahedron. 42: 2575-2586. DOI: 10.1016/0040-4020(86)80025-4  0.576
1986 BALDWIN JE, ADLINGTON RM, JAIN AU, KOLHE JN, PERRY MWD. ChemInform Abstract: Applications of the Thermal Ene Reaction of Aldehyde t-Butyl- and Phenylhydrazones. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198652097  0.454
1986 BALDWIN JE, ADLINGTON RM, BOTTARO JC, KOHLE JN, NEWINGTON IM, PERRY MWD. ChemInform Abstract: Azo Anions in Synthesis. Use of Trityl- and Diphenyl-4-pyridylmethylhydrazones for Reductive C - C Bond Formation. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198652096  0.48
1986 Baldwin JE, Adlington RM, Basak A, Flitsch SL, Petursson S, Turner NJ, Ting HH. Enzymatic synthesis of a new type of penicillin Journal of the Chemical Society, Chemical Communications. 975-976. DOI: 10.1002/Chin.198649357  0.717
1986 BALDWIN JE, ADLINGTON RM, BASAK A, FLITSCH SL, PETURSSON S, TURNER NJ, TING H. ChemInform Abstract: Enzymatic Synthesis of a New Type of Penicillin. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198649357  0.632
1986 BALDWIN JE, LOWE C, SCHOFIELD CJ, LEE E. ChemInform Abstract: A γ-Lactam Analogue of Penems Possessing Antibacterial Activity. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198649351  0.374
1986 BALDWIN JE, ADLINGTON RM, NEWINGTON IM. ChemInform Abstract: Azo Anions in Synthesis: α-Amino Carbanion Equivalents from tert-Butyldiphenylmethylhydrazones. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198624142  0.519
1986 BALDWIN JE, ADLINGTON RM, BIRCH DJ. ChemInform Abstract: Synthesis of L-β-(Isoxazolin-S-one-2-yl)-alanine: A Novel Method for the Synthesis of N-Substituted 3,4-Unsubstituted Isoxazolin-5-ones. Chemischer Informationsdienst. 17. DOI: 10.1002/chin.198617356  0.32
1985 Samson SM, Belagaje R, Blankenship DT, Chapman JL, Perry D, Skatrud PL, VanFrank RM, Abraham EP, Baldwin JE, Queener SW. Isolation, sequence determination and expression in Escherichia coli of the isopenicillin N synthetase gene from Cephalosporium acremonium. Nature. 318: 191-4. PMID 3903520 DOI: 10.1038/318191A0  0.318
1985 Baldwin JE, Moroney SE, Ting HH. A coupled enzyme assay for isopenicillin N synthetase. Analytical Biochemistry. 145: 183-7. PMID 3873879 DOI: 10.1016/0003-2697(85)90345-8  0.361
1985 Baldwin JE, Gagnon J, Ting H. N-terminal amino acid sequence and some properties of isopenicillin-N synthetase from Cephalosporium acremonium. Febs Letters. 188: 253-6. PMID 3839755 DOI: 10.1016/0014-5793(85)80382-3  0.339
1985 Baldwin JE, Otsuka M, Wallace PM. Synthesis of a naturally occurring inhibitor of glutamine synthetase, tabtoxinene-β-lactam Journal of the Chemical Society, Chemical Communications. 1549-1550. DOI: 10.1039/C39850001549  0.337
1985 Baldwin JE, Adlington RM, Chondrogianni J, Edenborough MS, Keeping JW, Ziegler CB. Structure and synthesis of new cyclopentenyl isonitriles from Trichoderma hamatum (Bon.) Bain. aggr. HLX 1379 Journal of the Chemical Society, Chemical Communications. 816-817. DOI: 10.1039/C39850000816  0.305
1985 Baldwin JE, Adlington RM, Birch DJ. Synthesis of L-quisqualic acid: a general method for enantio-efficient synthesis of β-aminoalanine derivatives Journal of the Chemical Society, Chemical Communications. 256-257. DOI: 10.1039/C39850000256  0.598
1985 Baldwin JE, Adlington RM, Birch DJ. Synthesis of -β-(isoxazolin-5-one-2-yl)-alanine: a novel method for the synthesis of -substituted 3,4-unsubstituted isoxazolin-5-ones Tetrahedron Letters. 26: 5931-5934. DOI: 10.1016/S0040-4039(00)98264-9  0.609
1985 Baldwin JE, Adlington RM, Rawlings BJ, Jones RH. The resolution of racemic 2-alkyl-1-aminocyclopropane-1-carboxylic acids Tetrahedron Letters. 26: 485-488. DOI: 10.1016/S0040-4039(00)61918-4  0.521
1985 Baldwin JE, Adlington RM, Rawlings BJ. A convenient synthesis of regio-specifically 2-alkylated-3-deuteriated-1-aminocyclopropane-1-carboxylic acids Tetrahedron Letters. 26: 481-484. DOI: 10.1016/S0040-4039(00)61917-2  0.532
1985 Baldwin JE, Adlington RM, Ting HH, Arigoni D, Graf P, Martinoni B. Penicillin biosynthesis the immediate origin of the sulphur atom Tetrahedron. 41: 3339-3343. DOI: 10.1016/S0040-4020(01)96685-2  0.716
1985 Baldwin JE, Bansal HS, Chondrogianni J, Field LD, Taha AA, Thaller V, Brewer D, Taylor A. Biosynthesis of 3-(3'-isocyanocyclopent-2-enylidene) propionic acid by (bon.) bain. aggr. Tetrahedron. 41: 1931-1938. DOI: 10.1016/S0040-4020(01)96556-1  0.371
1985 BALDWIN JE, ADLINGTON RM, CHONDROGIANNI J, EDENBOROUGH MS, KEEPING JW, ZIEGLER CB. ChemInform Abstract: STRUCTURE AND SYNTHESIS OF NEW CYCLOPENTENYL ISONITRILES FROM TRICHODERMA HAMATUM (BON.) BAIN. AGGR. HLX 1379 Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198541199  0.567
1985 BALDWIN JE, ADLINGTON RM, BOHLMANN R. ChemInform Abstract: BIOMIMETIC SYNTHESIS OF PENICILLIN Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198527367  0.534
1985 BALDWIN JE, ADLINGTON RM, JONES RH, SCHOFIELD CJ, ZAROCOSTAS C, GREENGRASS CW. ChemInform Abstract: γ-Lactam Analogues of Carbapenicillanic Acids. Chemischer Informationsdienst. 16. DOI: 10.1002/chin.198526375  0.421
1985 BALDWIN JE, ADLINGTON RM, BIRCH DJ. ChemInform Abstract: SYNTHESIS OF L-QUISQUALIC ACID: A GENERAL METHOD FOR ENANTIO-EFFICIENT SYNTHESIS OF β-AMINOALANINE DERIVATIVES Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198526342  0.613
1985 BALDWIN JE, ADLINGTON RM, BASAK A. ChemInform Abstract: ALLENE TRANSFER REACTIONS. A NEW SYNTHESIS OF TERMINAL ALLENES Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198505135  0.675
1985 BALDWIN JE, ADLINGTON RM, DEROME AE, TING H, TURNER NJ. ChemInform Abstract: PENICILLIN BIOSYNTHESIS: MULTIPLE PATHWAYS FROM A MODIFIED SUBSTRATE Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198504345  0.458
1985 BALDWIN JE, ADLINGTON RM, TURNER NJ, DOMAYNE-HAYMAN BP, TING H, DEROME AE, MURPHY JA. ChemInform Abstract: PENICILLIN BIOSYNTHESIS: ENZYMATIC SYNTHESIS OF NEW CEPHAMS Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198502370  0.577
1985 BALDWIN JE, ADLINGTON RM, BOTTARO JC, JAIN AU, KOLHE JN, PERRY MWD, NEWINGTON IM. ChemInform Abstract: MICHAEL ADDITIONS OF HYDRAZONES FOR CARBON-CARBON BOND FORMATION Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198501145  0.486
1984 Pang CP, Chakravarti B, Adlington RM, Ting HH, White RL, Jayatilake GS, Baldwin JE, Abraham EP. Purification of isopenicillin N synthetase. The Biochemical Journal. 222: 789-95. PMID 6435606 DOI: 10.1042/Bj2220789  0.459
1984 Baldwin JE, Beckwith PLM, Wallis JD, Orrell APK, Prout K. An approach to the synthesis of dodecahedrane: the X-ray crystal structures of six intermediate compounds Journal of the Chemical Society-Perkin Transactions 1. 15: 53-61. DOI: 10.1039/P29840000053  0.302
1984 Baldwin JE, Adlington RM, Basak A. Allene transfer reactions. A new synthesis of terminal allenes Journal of the Chemical Society, Chemical Communications. 1284-1285. DOI: 10.1039/C39840001284  0.708
1984 Baldwin JE, Abraham EP, Adlington RM. Penicillin biosynthesis: Active site mapping with aminoadipoylcysteinylvaline variants Journal of the Chemical Society - Series Chemical Communications. 1225-1227. DOI: 10.1039/C39840001225  0.531
1984 Baldwin JE, Adlington RM, Turner NJ, Domayne-Hayman BP, Ting H, Derome AE, Murphy JA. Penicillin biosynthesis: enzymatic synthesis of new cephams Journal of the Chemical Society, Chemical Communications. 1167-1170. DOI: 10.1039/C39840001167  0.594
1984 Baldwin JE, Adlington RM, Bottaro JC, Jain AU, Kolhe JN, Perry MWD, Newington IM. Michael additions of hydrazones for carbon–carbon bond formation Journal of the Chemical Society, Chemical Communications. 1095-1096. DOI: 10.1039/C39840001095  0.569
1984 Baldwin JE, Chan MF, Gallacher G, Otsuka M, Monk P, Prout K. γ-Lactam analogues of penicillanic and carbapenicillanic acids Tetrahedron. 40: 4513-4525. DOI: 10.1016/S0040-4020(01)98828-3  0.345
1984 Baldwin JE, Harwood LM, Lombard MJ. A general procedure for the synthesis of isoxazolidin-5-ones Tetrahedron. 40: 4363-4370. DOI: 10.1016/S0040-4020(01)98811-8  0.388
1984 Baldwin JE, Abraham SEP, Adlington RM, Crimmin MJ, Field LD, Jayatilake GS, White RL, Usher JJ. The synthesis and reactions of a monocyclic β-lactam tripeptide, 1-[(1R)-carboxy-2-methylpropyl]- (3R -[(5S-5-amino- 5-carboxypentanamido]-(4R)-mercaptoazetidin-2-one, a putative intermediate in penicillin biosynthesis Tetrahedron. 40: 1907-1918. DOI: 10.1016/S0040-4020(01)91148-2  0.566
1984 Baldwin JE, D. Bailey P, Gallacher G, Otsuka M, Singleton KA, Wallace PM, Prout K, Wolf WM. Stereospecific synthesis of tabtoxin Tetrahedron. 40: 3695-3708. DOI: 10.1016/S0040-4020(01)88799-8  0.372
1984 BALDWIN JE, BOTTARO JC, KOLHE JN, ADLINGTON RM. ChemInform Abstract: AZO ANIONS IN SYNTHESIS. USE OF TRITYL- AND DIPHENYL-4-PYRIDYLMETHYLHYDRAZONES FOR REDUCTIVE CARBON-CARBON BOND FORMATION FROM ALDEHYDES AND KETONES Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198419157  0.468
1984 ADLINGTON RM, BALDWIN JE, JONES RH, MURPHY JA, PARISI MF. ChemInform Abstract: STEREOSPECIFIC SYNTHESIS OF (1S,2S)-1-HYDROXY-2-((S)-VALYLAMINO)CYCLOBUTANE-1-ACETIC ACID, A NOVEL MICROBIAL ANTIMETABOLITE Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198417350  0.556
1984 ADLINGTON RM, BALDWIN JE, BOTTARO JC, PERRY MWD. ChemInform Abstract: AZO ANIONS IN SYNTHESIS. TERT-BUTYLHYDRAZONES AS ACYL ANION EQUIVALENTS Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198403132  0.525
1983 Adlington RM, Baldwin JE, Lopez-Nieto M, Murphy JA, Patel N. A study of the biosynthesis of the tripeptide delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine in a beta-lactam-negative mutant of Cephalosporium acremonium. The Biochemical Journal. 213: 573-6. PMID 6684424 DOI: 10.1042/Bj2130573  0.494
1983 Adlington RM, Baldwin JE, Jones RH, Murphy JA, Parisi MF. Stereospecific synthesis of (1S,2S)-1-hydroxy-2-[(S)-valylamino]-cyclobutane-1-acetic acid, a novel microbial antimetabolite Journal of the Chemical Society, Chemical Communications. 1479-1481. DOI: 10.1039/C39830001479  0.54
1983 Baldwin JE, Abraham EP, Adlington RM, Murphy JA, Green NB, Ting HH, Usher JJ. Penicillin biosynthesis. On the stereochemistry of carbon-sulphur bond formation with modified substrates Journal of the Chemical Society, Chemical Communications. 1319-1320. DOI: 10.1039/C39830001319  0.517
1983 Adlington RM, Baldwin JE, Chakravarti B, Jung M, Moroney SE, Murphy JA, Singh PD, Usher JJ, Vallejo C. Conversion of 3-exomethylene cephalosporin C into deacetyl cephalosporin C in a cell-free extract from Cephalosporium acremonium(CW-19) Journal of the Chemical Society, Chemical Communications. 153-154. DOI: 10.1039/C39830000153  0.481
1983 Adlington RM, Aplin RT, Baldwin JE, Chakravarti B, Field LD, John EMM, Abraham EP, White RL. Conversion of 17O/18O labelled δ-(L-α-aminoadlpyl)-L-cysteinyl-D-valine to 17O/18O labelled isopenicillin n in a cell-free extract of cephalosporium acremonium. A study by 17O-NMR spectroscopy and mass spectrometry Tetrahedron. 39: 1061-1068. DOI: 10.1016/S0040-4020(01)91867-8  0.505
1983 Baldwin JE, Lopez R. Addition reactions of some simple thioaldehydes Tetrahedron. 39: 1487-1498. DOI: 10.1016/S0040-4020(01)88553-7  0.317
1983 ADLINGTON RM, BALDWIN JE, BASAK A, KOZYROD RP. ChemInform Abstract: APPLICATIONS OF RADICAL ADDITION REACTIONS TO THE SYNTHESIS OF A C-GLUCOSIDE AND A FUNCTIONALIZED AMINO ACID Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198352326  0.664
1983 ADLINGTON RM, BALDWIN JE, CHAKRAVARTI B, JUNG M, MORONEY SE, MURPHY JA, SINGH PD, USHER JJ, VALLEJO C. ChemInform Abstract: CONVERSION OF 3-EXOMETHYLENE CEPHALOSPORIN C INTO DEACETYL CEPHALOSPORIN C IN A CELL-FREE EXTRACT FROM CEPHALOSPORIUM ACREMONIUM (CW-19) Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198326346  0.516
1983 ABRAHAM EP, ADLINGTON RM, BALDWIN JE, CRIMMIN MJ, FIELD LD, JAYATILAKE GS, WHITE RL. ChemInform Abstract: MONOCYCLIC β-LACTAM TRIPEPTIDE, 1-(D-CARBOXY-2-METHYLPROPYL)-3-L-(Δ-L-2-AMINOADIPAMIDO)-4-L-MERCAPTOAZETI# DIN-2-ONE, A PUTATIVE INTERMEDIATE IN PENICILLIN BIOSYNTHESIS Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198309319  0.499
1983 BALDWIN JE, DAVIS AP, FIELD LD. ChemInform Abstract: THE STEREOCHEMISTRY OF CYCLIZATION OF N-TERT-BUTYLDIHYDROCINNAMAMIDE TO A β-LACTAM Chemischer Informationsdienst. 14. DOI: 10.1002/chin.198306091  0.487
1982 Abraham EP, Adlington RM, Baldwin JE. Monocyclic β-lactam tripeptide, 1-(D-carboxy-2-methylpropyl)-3-L-(δ-L-2- aminoadipamido)-4-L-mercaptoazetidin-2-one, a putative intermediate in penicillin biosynthesis Journal of the Chemical Society - Series Chemical Communications. 1130-1132. DOI: 10.1039/C39820001130  0.529
1982 Adlington RM, Aplin RT, Baldwin JE, Field LD, John EMM, Abraham EP, White RL. Conversion of 17O/18O-labelled δ-(L-α- aminoadipyl)-L-cysteinyl-D-valine into 17O/18O-labelled isopenicillin N in a cell-free extract of C. acremonium Journal of the Chemical Society, Chemical Communications. 137-139. DOI: 10.1039/C39820000137  0.448
1982 Baldwin JE, Lusch MJ. Rules for ring closure: application to intramolecular aldol condensations in polyketonic substrates Tetrahedron. 38: 2939-2947. DOI: 10.1016/0040-4020(82)85023-0  0.396
1982 Baldwin JE, Davis AP, Field LD. The stereochemistry of cyclisation of n--butyldihydrocinnamamide to a β-lactam Tetrahedron. 38: 2777-2781. DOI: 10.1016/0040-4020(82)85003-5  0.537
1982 Baldwin JE, Chakravarti B, Field LD, Murphy JA, Whitten KR, Abraham SEP, Jayatilake G. The synthesis of l-α-aminoadipyl-l-cysteinyl-d-3,4-didehydrovaline, a potent inhibitor of isopenicillin synthetase Tetrahedron. 38: 2773-2776. DOI: 10.1016/0040-4020(82)85002-3  0.376
1981 Baldwin JE, Davis AP. Penicillin biosynthesis: A model for the oxidative cyclisation of a peptide to a β-lactam Journal of the Chemical Society, Chemical Communications. 1219-1221. DOI: 10.1039/C39810001219  0.48
1981 Crout DHG, Lutstorf M, Morgan PJ, Adlington RM, Baldwin JE, Crimmin MJ. Unusual stereospecificity in the hydrogenation of an isopropenyl function with Wilkinson's catalyst; a route to chiral methyl valine Journal of the Chemical Society, Chemical Communications. 1175-1176. DOI: 10.1039/C39810001175  0.459
1981 Ross WJ, Todd A, Clark BP, Morgan SE, Baldwin JE. The synthesis and rearrangement of epoxypyrones Tetrahedron Letters. 22: 2207-2208. DOI: 10.1016/S0040-4039(01)90499-X  0.393
1981 Baldwin JE, Beckwith ALJ, Davis AP, Procter G, Singleton KA. 5-Isothiazolidinonyl and 5-isoxazolidinonyl radicals. Approaches to the biogenetic-type synthesis of β-lactams Tetrahedron. 37: 2181-2189. DOI: 10.1016/S0040-4020(01)97977-3  0.485
1980 Baldwin JE, Cacioli P, Reiss JA. Phenoxathiins from spiroepoxycyclohexadienones Tetrahedron Letters. 21: 4971-4972. DOI: 10.1016/S0040-4039(00)71168-3  0.306
1979 Baldwin JE, Lusch MJ. Rearrangements in Lewis acid catalyzed Diels-Alder reactions. Route to substituted bicyclo[2.2.1]heptanones The Journal of Organic Chemistry. 44: 1923-1927. DOI: 10.1021/Jo01326A006  0.387
1979 Baldwin J, Singh P. Model studies towards the synthesis of 2-β-hydroxymethyl penicillin N Tetrahedron Letters. 20: 3757-3760. DOI: 10.1016/S0040-4039(01)95517-0  0.352
1977 Davies DI, Hughes L, Vankar YD, Baldwin JE. Synthesis of 1,4-oxathian-2-one, 5-methyl-1,4-oxathian-2-one, and 1,4-oxathiepan-2-one Journal of the Chemical Society-Perkin Transactions 1. 9: 2476-2479. DOI: 10.1039/P19770002476  0.338
1975 Almog J, Baldwin JE, Dyer RL, Peters M. Condensation of tetraaldehydes with pyrrole. Direct synthesis of capped porphyrins Journal of the American Chemical Society. 97: 226-227. DOI: 10.1021/Ja00834A059  0.367
1971 Baldwin JE, Barton DH, Gutteridge NJ, Martin RJ. Experiments on the synthesis of tetracycline. IV. Ring B formation through 1,3-dipolar additions. Journal of the Chemical Society. Perkin Transactions 1. 12: 2184-92. PMID 5170047 DOI: 10.1039/J39710002184  0.647
1971 Aufderhaar E, Baldwin JE, Barton DH, Faulkner DJ, Slaytor M. Experiments on the synthesis of tetracycline. 3. Michael-type cyclisation in the formation of ring B. Journal of the Chemical Society. Perkin Transactions 1. 12: 2175-83. PMID 5170046 DOI: 10.1039/J39710002175  0.705
1971 AUFDERHAAR E, BALDWIN JE, BARTON DHR, FAULKNER DJ, SLAYTOR M. ChemInform Abstract: VERSUCHE ZUR SYNTH. VON TETRACYCLIN 3. MITT. CYCLISIERUNG VOM MICHAEL-TYP BEI DER BLDG. VON RING B Chemischer Informationsdienst. Organische Chemie. 2: no-no. DOI: 10.1002/chin.197139390  0.416
1968 Baldwin JE, Barton DH, Dainis I, Pereira JL. Photochemical transformations. XXIV. The synthesis of 18-hydroxyoestrone. Journal of the Chemical Society. Perkin Transactions 1. 18: 2283-9. PMID 5693074  0.626
1962 BALDWIN JE, BARTON DH, BLOOMER JL, JACKMAN LM, RODRIGUEZ-HAHN L, SUTHERLAND JK. The constitutions of glauconic, glaucanic and byssochlamic acids. Experientia. 18: 345-52. PMID 13864341 DOI: 10.1007/BF02172243  0.721
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