Paul S. Frenette - Publications

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Immunology, Neuroscience Biology, Pharmacology

212 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Vercellino J, Małachowska B, Kulkarni S, Bell BI, Shajahan S, Shinoda K, Eichenbaum G, Verma AK, Ghosh SP, Yang WL, Frenette PS, Guha C. Thrombopoietin mimetic stimulates bone marrow vascular and stromal niches to mitigate acute radiation syndrome. Research Square. PMID 38463959 DOI: 10.21203/rs.3.rs-3946910/v1  0.336
2023 Marchand T, Akinnola KE, Takeishi S, Maryanovich M, Pinho S, Saint-Vanne J, Birbrair A, Lamy T, Tarte K, Frenette PS, Gritsman K. Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury. Biorxiv : the Preprint Server For Biology. PMID 36711927 DOI: 10.1101/2023.01.12.523842  0.629
2022 Picoli CC, Martins PR, Wong XLC, Righi T, Guimarães PPG, Pinto MCX, Amorim JH, Azevedo VAC, Pereira SR, Kanashiro A, Cruz FC, Resende RR, Mintz A, Frenette PS, Birbrair A. Whole bone subcutaneous transplantation as a strategy to study precisely the bone marrow niche. Stem Cell Reviews and Reports. PMID 36585572 DOI: 10.1007/s12015-022-10496-9  0.633
2022 Rocha BGS, Picoli CC, Gonçalves BOP, Silva WN, Costa AC, Moraes MM, Costa PAC, Santos GSP, Almeida MR, Silva LM, Singh Y, Falchetti M, Guardia GDA, Guimarães PPG, Russo RC, ... ... Frenette PS, et al. Tissue-resident glial cells associate with tumoral vasculature and promote cancer progression. Angiogenesis. PMID 36183032 DOI: 10.1007/s10456-022-09858-1  0.573
2022 Bogeska R, Mikecin AM, Kaschutnig P, Fawaz M, Büchler-Schäff M, Le D, Ganuza M, Vollmer A, Paffenholz SV, Asada N, Rodriguez-Correa E, Frauhammer F, Buettner F, Ball M, Knoch J, ... ... Frenette PS, et al. Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging. Cell Stem Cell. 29: 1273-1284.e8. PMID 35858618 DOI: 10.1016/j.stem.2022.06.012  0.343
2022 Pinho S, Wei Q, Maryanovich M, Zhang D, Balandrán JC, Pierce H, Nakahara F, Di Staulo A, Bartholdy BA, Xu J, Borger DK, Verma A, Frenette PS. VCAM1 confers innate immune tolerance on haematopoietic and leukaemic stem cells. Nature Cell Biology. PMID 35210567 DOI: 10.1038/s41556-022-00849-4  0.362
2021 Nobre AR, Risson E, Singh DK, Di Martino JS, Cheung JF, Wang J, Johnson J, Russnes HG, Bravo-Cordero JJ, Birbrair A, Naume B, Azhar M, Frenette PS, Aguirre-Ghiso JA. Bone marrow NG2/Nestin mesenchymal stem cells drive DTC dormancy TGFβ2. Nature Cancer. 2: 327-339. PMID 34993493 DOI: 10.1038/s43018-021-00179-8  0.636
2021 Wei Q, Pinho S, Dong S, Pierce H, Li H, Nakahara F, Xu J, Xu C, Boulais PE, Zhang D, Maryanovich M, Cuervo AM, Frenette PS. MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells. Nature Communications. 12: 2522. PMID 33947846 DOI: 10.1038/s41467-021-22749-1  0.325
2021 Renders S, Svendsen AF, Panten J, Rama N, Maryanovich M, Sommerkamp P, Ladel L, Redavid AR, Gibert B, Lazare S, Ducarouge B, Schönberger K, Narr A, Tourbez M, Dethmers-Ausema B, ... ... Frenette PS, et al. Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1. Nature Communications. 12: 608. PMID 33504783 DOI: 10.1038/s41467-020-20801-0  0.319
2021 Venkatraman A, Smith SE, Pinho S, Zhao M, Li L, Frenette P. In Situ Hematopoietic Stem Cell Imaging. Methods in Molecular Biology (Clifton, N.J.). 2185: 373-382. PMID 33165861 DOI: 10.1007/978-1-0716-0810-4_23  0.31
2020 Xu C, Lee SK, Zhang D, Frenette PS. The Gut Microbiome Regulates Psychological-Stress-Induced Inflammation. Immunity. PMID 32735844 DOI: 10.1016/J.Immuni.2020.06.025  0.308
2020 Ferreira WA, Chweih H, Lanaro C, Almeida CB, Brito PL, Gotardo EM, Torres L, Miguel LI, Franco-Penteado CF, Leonardo FC, Garcia F, Saad ST, Frenette PS, Brockschnieder D, Costa FF, et al. Beneficial Effects of Soluble Guanylyl Cyclase Stimulation and Activation in Sickle Cell Disease are Amplified by Hydroxyurea: and Studies. The Journal of Pharmacology and Experimental Therapeutics. PMID 32631869 DOI: 10.1124/Jpet.119.264606  0.384
2020 Wei Q, Nakahara F, Asada N, Zhang D, Gao X, Xu C, Alfieri A, Brodin NP, Zimmerman SE, Mar JC, Guha C, Guo W, Frenette PS. Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression. Developmental Cell. PMID 32413329 DOI: 10.1016/J.Devcel.2020.04.012  0.46
2019 Jordan S, Tung N, Casanova-Acebes M, Chang C, Cantoni C, Zhang D, Wirtz TH, Naik S, Rose SA, Brocker CN, Gainullina A, Hornburg D, Horng S, Maier BB, Cravedi P, ... ... Frenette PS, et al. Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool. Cell. 178: 1102-1114.e17. PMID 31442403 DOI: 10.1016/J.Cell.2019.07.050  0.537
2019 Tikhonova AN, Dolgalev I, Hu H, Sivaraj KK, Hoxha E, Cuesta-Domínguez Á, Pinho S, Akhmetzyanova I, Gao J, Witkowski M, Guillamot M, Gutkin MC, Zhang Y, Marier C, Diefenbach C, ... ... Frenette PS, et al. Author Correction: The bone marrow microenvironment at single-cell resolution. Nature. PMID 31296938 DOI: 10.1038/S41586-019-1394-X  0.367
2019 Hanoun M, Arnal-Estapé A, Maryanovich M, Zahalka AH, Bergren SK, Chua CW, Leftin A, Brodin PN, Shen MM, Guha C, Frenette PS. NestinNG2 Cells Form a Reserve Stem Cell Population in the Mouse Prostate. Stem Cell Reports. PMID 31130357 DOI: 10.1016/J.Stemcr.2019.04.019  0.37
2019 Nakahara F, Borger DK, Wei Q, Pinho S, Maryanovich M, Zahalka AH, Suzuki M, Cruz CD, Wang Z, Xu C, Boulais PE, Ma'ayan A, Greally JM, Frenette PS. Engineering a haematopoietic stem cell niche by revitalizing mesenchymal stromal cells. Nature Cell Biology. PMID 30988422 DOI: 10.1038/S41556-019-0308-3  0.452
2019 Tikhonova AN, Dolgalev I, Hu H, Sivaraj KK, Hoxha E, Cuesta-Domínguez Á, Pinho S, Akhmetzyanova I, Gao J, Witkowski M, Guillamot M, Gutkin MC, Zhang Y, Marier C, Diefenbach C, ... ... Frenette PS, et al. The bone marrow microenvironment at single-cell resolution. Nature. PMID 30971824 DOI: 10.1038/S41586-019-1104-8  0.426
2019 Xu C, Frenette PS. Seasonal manifestations of sickle cell disease activity. Nature Medicine. 25: 536-537. PMID 30948854 DOI: 10.1038/S41591-019-0409-3  0.324
2019 Maryanovich M, Zahalka AH, Pierce H, Pinho S, Nakahara F, Asada N, Wei Q, Wang X, Ciero P, Xu J, Leftin A, Frenette PS. Author Correction: Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. Nature Medicine. PMID 30903101 DOI: 10.1038/S41591-019-0425-3  0.371
2019 Pinho S, Frenette PS. Haematopoietic stem cell activity and interactions with the niche. Nature Reviews. Molecular Cell Biology. PMID 30745579 DOI: 10.1038/S41580-019-0103-9  0.478
2019 Wei Q, Boulais PE, Zhang D, Pinho S, Tanaka M, Frenette PS. Maea expressed by macrophages, but not erythroblasts, maintains postnatal murine bone marrow erythroblastic islands. Blood. PMID 30674470 DOI: 10.1182/Blood-2018-11-888180  0.412
2019 Bogeska R, Kaschutnig P, Paffenholz SV, Knoch J, Mallm J, Fawaz M, Buettner F, Walter D, Frauhammer F, Holland-Letz T, Asada N, Mikecin Drazic A, Buechler-Schaff M, Correno-Gonzalez M, Ball M, ... ... Frenette PS, et al. No Evidence for Hematopoietic Stem Cell Self-Renewal in-Vivo Following Inflammatory Challenge Blood. 134: 456-456. DOI: 10.1182/Blood-2019-125744  0.468
2019 Nakahara F, Pinho S, Borger DK, Wei Q, Maryanovich M, Zahalka AH, Suzuki M, Cruz C, Wang Z, Xu C, Boulais P, Ma'ayan A, Greally JM, Frenette PS. Engineering a Hematopoietic Stem Cell Niche By Revitalizing Mesenchymal Stem Cells with Five Transcription Factors Blood. 134: 5004-5004. DOI: 10.1182/Blood-2019-125045  0.442
2019 GAO X, Boulais P, Tanaka M, Marlein CR, Frenette PS. Macrophage Transfer to HSCs Assigns Residence in Bone Marrow Blood. 134: 276-276. DOI: 10.1182/Blood-2019-123762  0.398
2019 Pinho S, Wei Q, Maryanovich M, Pierce H, Nakahara F, Xu J, Borger DK, Zhang D, Verma A, Frenette PS. VCAM1 Confers Innate Immune Tolerance on Hematopoietic and Leukemic Stem Cells Blood. 134: 524-524. DOI: 10.1182/Blood-2019-123431  0.424
2019 Xu C, Lee S, Frenette PS. The Gut Microbiome Regulates Psychological Stress-Induced Inflammation in Sickle Cell Disease Blood. 134: 205-205. DOI: 10.1182/Blood-2019-122331  0.306
2019 Nakahara F, Borger D, Wei Q, Pinho S, Maryanovich M, Zahalka A, Suzuki M, Cruz C, Wang Z, Xu C, Boulais P, Ma'ayan A, Greally J, Frenette P. 2011 - ENGINEERING A HEMATOPOIETIC STEM CELL NICHE BY REVITALIZING MESENCHYMAL STEM CELLS Experimental Hematology. 76: S45. DOI: 10.1016/J.Exphem.2019.06.285  0.436
2018 Boulais PE, Mizoguchi T, Zimmerman S, Nakahara F, Vivié J, Mar JC, van Oudenaarden A, Frenette PS. The Majority of CD45 Ter119 CD31 Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors. Immunity. 49: 627-639.e6. PMID 30314756 DOI: 10.1016/J.Immuni.2018.08.019  0.34
2018 Xu C, Gao X, Wei Q, Nakahara F, Zimmerman SE, Mar J, Frenette PS. Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow. Nature Communications. 9: 2449. PMID 29934585 DOI: 10.1038/S41467-018-04726-3  0.494
2018 Maryanovich M, Zahalka AH, Pierce H, Pinho S, Nakahara F, Asada N, Wei Q, Wang X, Ciero P, Xu J, Leftin A, Frenette PS. Adrenergic nerve degeneration in bone marrow drives aging of the hematopoietic stem cell niche. Nature Medicine. PMID 29736022 DOI: 10.1038/S41591-018-0030-X  0.411
2018 Wei Q, Frenette PS. Niches for Hematopoietic Stem Cells and Their Progeny. Immunity. 48: 632-648. PMID 29669248 DOI: 10.1016/J.Immuni.2018.03.024  0.447
2018 Maryanovich M, Takeishi S, Frenette PS. Neural Regulation of Bone and Bone Marrow. Cold Spring Harbor Perspectives in Medicine. PMID 29500307 DOI: 10.1101/Cshperspect.A031344  0.373
2018 Hirata Y, Furuhashi K, Ishii H, Li HW, Pinho S, Ding L, Robson SC, Frenette PS, Fujisaki J. CD150Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine. Cell Stem Cell. PMID 29456159 DOI: 10.1016/J.Stem.2018.01.017  0.455
2018 Pinho S, Marchand T, Yang E, Wei Q, Nerlov C, Frenette PS. Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches. Developmental Cell. PMID 29456137 DOI: 10.1016/J.Devcel.2018.01.016  0.452
2018 Gao X, Xu C, Asada N, Frenette PS. The hematopoietic stem cell niche: from embryo to adult. Development (Cambridge, England). 145. PMID 29358215 DOI: 10.1242/Dev.139691  0.423
2018 Guarnerio J, Mendez LM, Asada N, Menon AV, Fung J, Berry K, Frenette PS, Ito K, Pandolfi PP. A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche. Nature Communications. 9: 66. PMID 29302031 DOI: 10.1038/S41467-017-02427-X  0.44
2018 Pinho S, Frenette P. Imaging Hematopoietic Stem Cells in Their Native Bone Marrow Microenvironment Experimental Hematology. 64: S94. DOI: 10.1016/J.Exphem.2018.06.122  0.415
2018 Maryanovich M, Zahalka A, Pierce H, Pinho S, Nakahara F, Asada N, Wei Q, Wang X, Frenette P. Adrenergic Nerve Degeneration in the Bone Marrow Drives Aging of the Hematopoietic Stem Cell Niche Experimental Hematology. 64. DOI: 10.1016/J.Exphem.2018.06.085  0.411
2018 Boulais P, Mizoguchi T, Zimmerman S, Nakahara F, Vivié J, Mar J, van Oudenaarden A, Frenette P. Stromal-Dependent Hematopoietic Progenitors Permeate the CD45 CD31 Ter119 Bone Marrow Cell Fraction Experimental Hematology. 64: S49-S50. DOI: 10.1016/J.Exphem.2018.06.066  0.372
2018 Wei Q, Pinho S, Pierce H, Xu C, Nakahara F, Boulais P, Zhang D, Li H, Maryanovich M, Frenette P. Maea is a Critical Regulator of Hematopoietic Stem Cell and Erythroblastic Island Macrophage Maintenance Experimental Hematology. 64: S46. DOI: 10.1016/J.Exphem.2018.06.057  0.436
2017 Bowers E, Slaughter A, Frenette PS, Kuick R, Pello OM, Lucas D. Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow. Nature Medicine. PMID 29155425 DOI: 10.1038/Nm.4448  0.498
2017 Zahalka AH, Arnal-Estapé A, Maryanovich M, Nakahara F, Cruz CD, Finley LWS, Frenette PS. Adrenergic nerves activate an angio-metabolic switch in prostate cancer. Science (New York, N.Y.). 358: 321-326. PMID 29051371 DOI: 10.1126/Science.Aah5072  0.307
2017 Cossarizza A, Chang HD, Radbruch A, Andrä I, Annunziato F, Bacher P, Barnaba V, Battistini L, Bauer WM, Baumgart S, Becher B, Beisker W, Berek C, Blanco A, Borsellino G, ... ... Frenette PS, et al. Guidelines for the use of flow cytometry and cell sorting in immunological studies. European Journal of Immunology. 47: 1584-1797. PMID 29023707 DOI: 10.1002/Eji.201646632  0.329
2017 Shastri A, Budhathoki A, Barta SK, Kornblum N, Derman O, Battini R, Ragupathy R, Verma A, Frenette PS, Braunschweig I, Janakiram M. Stimulation of Adrenergic Activity by Desipramine Enhances Hematopoietic Stem and Progenitor Cell Mobilization along with G-CSF in Multiple Myeloma - A Pilot Study. American Journal of Hematology. PMID 28675459 DOI: 10.1002/Ajh.24843  0.367
2017 Maryanovich M, Frenette PS. T-Regulating Hair Follicle Stem Cells. Immunity. 46: 979-981. PMID 28636968 DOI: 10.1016/J.Immuni.2017.06.011  0.419
2017 Asada N, Takeishi S, Frenette PS. Complexity of bone marrow hematopoietic stem cell niche. International Journal of Hematology. PMID 28534115 DOI: 10.1007/S12185-017-2262-9  0.48
2017 Asada N, Kunisaki Y, Pierce H, Wang Z, Fernandez NF, Birbrair A, Ma'ayan A, Frenette PS. Differential cytokine contributions of perivascular haematopoietic stem cell niches. Nature Cell Biology. PMID 28218906 DOI: 10.1038/Ncb3475  0.696
2017 Pierce H, Zhang D, Magnon C, Lucas D, Christin JR, Huggins M, Schwartz GJ, Frenette PS. Cholinergic Signals from the CNS Regulate G-CSF-Mediated HSC Mobilization from Bone Marrow via a Glucocorticoid Signaling Relay. Cell Stem Cell. PMID 28196601 DOI: 10.1016/J.Stem.2017.01.002  0.416
2017 Bogeska R, Kaschutnig P, Paffenholz S, Knoch J, Walter D, Mallm J, Frauhammer F, Blaszkiewicz S, Holland-Letz T, Asada N, Gräsel J, Stäble S, Prendergast Á, Haas S, Lipka D, ... ... Frenette P, et al. HSCs completely fail to regenerate following inflammatory challenge, leading to aged hematopoiesis Experimental Hematology. 53: S124. DOI: 10.1016/J.Exphem.2017.06.310  0.308
2016 Ito K, Turcotte R, Cui J, Zimmerman SE, Pinho S, Mizoguchi T, Arai F, Runnels JM, Alt C, Teruya-Feldstein J, Mar JC, Singh R, Suda T, Lin CP, Frenette PS, et al. Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance. Science (New York, N.Y.). PMID 27738012 DOI: 10.1126/Science.Aaf5530  0.392
2016 Ito K, Frenette PS. HSC Contribution in Making Steady-State Blood. Immunity. 45: 464-6. PMID 27653597 DOI: 10.1016/J.Immuni.2016.09.002  0.391
2016 Chen G, Chang J, Zhang D, Pinho S, Jang JE, Frenette PS. Targeting Mac-1-mediated leukocyte-RBC interactions uncouples the benefits for acute vaso-occlusion and chronic organ damage. Experimental Hematology. PMID 27393574 DOI: 10.1016/J.Exphem.2016.06.252  0.716
2016 Maryanovich M, Frenette PS. A Time Bomb for Leukemia. Cell. 165: 262-3. PMID 27058656 DOI: 10.1016/J.Cell.2016.03.024  0.353
2016 Birbrair A, Frenette PS. Niche heterogeneity in the bone marrow. Annals of the New York Academy of Sciences. PMID 27015419 DOI: 10.1111/Nyas.13016  0.685
2016 Zhang D, Xu C, Manwani D, Frenette PS. Neutrophils, platelets, and inflammatory pathways, at the nexus of sickle cell disease pathophysiology. Blood. PMID 26758915 DOI: 10.1182/Blood-2015-09-618538  0.348
2016 Boulais PE, van Rooijen N, Tanaka M, Frenette PS. F4/80 Identifies a Subset of Non-Mobilizable Bone Marrow HSCs Involved in Stress-Induced Hematopoiesis Blood. 128: 569-569. DOI: 10.1182/Blood.V128.22.569.569  0.384
2016 Pinho S, Qiaozhi W, Maryanovich M, Pierce H, Nakahara F, Frenette PS. Vcam1 Is a Don't-Eat-Me Signal on Healthy Hematopoietic and Leukemic Stem Cells Blood. 128: 565-565. DOI: 10.1182/Blood.V128.22.565.565  0.529
2016 Maryanovich M, Zahalka AH, Pierce H, Pinho S, Nakahara F, Asada N, Leftin A, Vijg J, Frenette PS. Loss of Adrenergic Nerves in the Bone Marrow Microenvironment Drives an Aging HSC Niche Phenotype Blood. 128: 169-169. DOI: 10.1182/Blood.V128.22.169.169  0.441
2016 Bogeska R, Kaschutnig P, Paffenholz S, Maassen J, Mallm J, Wertek F, Walter D, Sandra B, Holland-Letz T, Asada N, Gräsel J, Stäble S, Block M, Gizlenci Ö, Prendergast ÁM, ... ... Frenette PS, et al. Hematopoietic Stem Cells Fail to Regenerate In Vivo Following Inflammatory Stress Blood. 128: 1472-1472. DOI: 10.1182/Blood.V128.22.1472.1472  0.477
2016 Frenette P. Hematopoietic stem cell niche through the ages Experimental Hematology. 44: S33. DOI: 10.1016/J.Exphem.2016.06.027  0.377
2015 Feintuch CM, Saidi A, Seydel K, Chen G, Goldman-Yassen A, Mita-Mendoza NK, Kim RS, Frenette PS, Taylor T, Daily JP. Activated Neutrophils Are Associated with Pediatric Cerebral Malaria Vasculopathy in Malawian Children. Mbio. 7. PMID 26884431 DOI: 10.1128/Mbio.01300-15  0.314
2015 Khan JA, Mendelson A, Kunisaki Y, Birbrair A, Kou Y, Arnal-Estapé A, Pinho S, Ciero P, Nakahara F, Ma'ayan A, Bergman A, Merad M, Frenette PS. Fetal liver hematopoietic stem cell niches associate with portal vessels. Science (New York, N.Y.). PMID 26634440 DOI: 10.1126/Science.Aad0084  0.718
2015 Zhang D, Chen G, Manwani D, Mortha A, Xu C, Faith JJ, Burk RD, Kunisaki Y, Jang JE, Scheiermann C, Merad M, Frenette PS. Neutrophil ageing is regulated by the microbiome. Nature. PMID 26374999 DOI: 10.1038/Nature15367  0.76
2015 Frenette PS. No "Kindlin," it's all about HSC balance. The Journal of Experimental Medicine. 212: 1341-2. PMID 26304981 DOI: 10.1084/Jem.2129Insight3  0.376
2015 Hanoun M, Maryanovich M, Arnal-Estapé A, Frenette PS. Neural regulation of hematopoiesis, inflammation, and cancer. Neuron. 86: 360-73. PMID 25905810 DOI: 10.1016/J.Neuron.2015.01.026  0.38
2015 Boulais PE, Frenette PS. Making sense of hematopoietic stem cell niches. Blood. 125: 2621-9. PMID 25762174 DOI: 10.1182/Blood-2014-09-570192  0.462
2015 Scheiermann C, Frenette PS, Hidalgo A. Regulation of leucocyte homeostasis in the circulation. Cardiovascular Research. 107: 340-51. PMID 25750191 DOI: 10.1093/Cvr/Cvv099  0.378
2015 Manwani D, Chen G, Carullo V, Serban S, Olowokure O, Jang J, Huggins M, Cohen HW, Billett H, Atweh GF, Frenette PS, Shi PA. Single-dose intravenous gammaglobulin can stabilize neutrophil Mac-1 activation in sickle cell pain crisis. American Journal of Hematology. 90: 381-5. PMID 25616042 DOI: 10.1002/Ajh.23956  0.353
2015 Pierce H, Magnon C, Lucas D, Huggins M, Schwartz GJ, Frenette PS. Muscarinic Receptor Type-1 Regulates Centrally Hematopoietic Stem Cell Mobilization By Granulocyte-Colony Stimulating Factor Via the Hypothalamic-Pituitary Axis Blood. 126: 898-898. DOI: 10.1182/Blood.V126.23.898.898  0.469
2015 Asada N, Kunisaki Y, Nagasawa T, Frenette PS. Distinct Contributions By Perivascular Niche Cells in Hematopoietic Stem Cell Maintenance Blood. 126: 661-661. DOI: 10.1182/Blood.V126.23.661.661  0.5
2015 Shastri A, Braunschweig I, Barta SK, Kornblum N, Derman O, Battini R, Verma A, Frenette PS, Janakiram M. Stimulation of Adrenergic Activity By Desipramine Enhances Hematopoietic Stem and Progenitor Cell Mobilization Along with G-CSF in Multiple Myeloma - a Pilot Study of Safety and Efficacy Blood. 126: 3101-3101. DOI: 10.1182/Blood.V126.23.3101.3101  0.366
2015 Zhang D, Chen G, Manwani D, Mortha A, Xu C, Faith JJ, Burk RD, Kunisaki Y, Jang J, Scheiermann C, Merad M, Frenette PS. Targeting Neutrophil Aging and the Microbiota for the Treatment of Sickle Cell Disease Blood. 126: 279-279. DOI: 10.1182/Blood.V126.23.279.279  0.414
2015 Wei Q, Frenette PS. Macrophage Erythroblast Attacher (MAEA), but Not VCAM1, Is Required for the Bone Marrow Erythroblastic Niche Blood. 126: 2128-2128. DOI: 10.1182/Blood.V126.23.2128.2128  0.49
2014 Bruns I, Lucas D, Pinho S, Ahmed J, Lambert MP, Kunisaki Y, Scheiermann C, Schiff L, Poncz M, Bergman A, Frenette PS. Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion. Nature Medicine. 20: 1315-20. PMID 25326802 DOI: 10.1038/Nm.3707  0.512
2014 Mendelson A, Frenette PS. Hematopoietic stem cell niche maintenance during homeostasis and regeneration. Nature Medicine. 20: 833-46. PMID 25100529 DOI: 10.1038/Nm.3647  0.45
2014 Lucas D, Frenette PS. Stem cells: Reprogramming finds its niche. Nature. 511: 301-2. PMID 25030164 DOI: 10.1038/Nature13516  0.469
2014 Hanoun M, Zhang D, Mizoguchi T, Pinho S, Pierce H, Kunisaki Y, Lacombe J, Armstrong SA, Dührsen U, Frenette PS. Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell niche. Cell Stem Cell. 15: 365-75. PMID 25017722 DOI: 10.1016/J.Stem.2014.06.020  0.751
2014 Mizoguchi T, Pinho S, Ahmed J, Kunisaki Y, Hanoun M, Mendelson A, Ono N, Kronenberg HM, Frenette PS. Osterix marks distinct waves of primitive and definitive stromal progenitors during bone marrow development. Developmental Cell. 29: 340-9. PMID 24823377 DOI: 10.1016/J.Devcel.2014.03.013  0.448
2014 Ono N, Ono W, Mizoguchi T, Nagasawa T, Frenette PS, Kronenberg HM. Vasculature-associated cells expressing nestin in developing bones encompass early cells in the osteoblast and endothelial lineage. Developmental Cell. 29: 330-9. PMID 24823376 DOI: 10.1016/J.Devcel.2014.03.014  0.475
2014 Kunisaki Y, Frenette PS. Influences of vascular niches on hematopoietic stem cell fate. International Journal of Hematology. 99: 699-705. PMID 24756874 DOI: 10.1007/S12185-014-1580-4  0.45
2014 Chen G, Zhang D, Fuchs TA, Manwani D, Wagner DD, Frenette PS. Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease. Blood. 123: 3818-27. PMID 24620350 DOI: 10.1182/Blood-2013-10-529982  0.575
2014 Manwani D, Chen G, Carullo V, Cohen HW, Serban S, Olowukere O, Jang J, Huggins M, Billett HH, Atweh GF, Frenette PS, Shi PA. Vaso-Occlusion-Promoting Neutrophil Mac-1 Integrin Activation in Human Sickle Cell Crises Is Stabilized By a Single Dose of Intravenous Gammaglobulin Blood. 124: 4089-4089. DOI: 10.1182/Blood.V124.21.4089.4089  0.37
2014 Ahmed J, Kunisake Y, Pinho S, Arnal A, Merad M, Frenette P. Ductus venosus-associated pericytes form a niche regulating hematopoietic stem cell proliferation in the fetal liver Experimental Hematology. 42: S19. DOI: 10.1016/J.Exphem.2014.07.067  0.563
2014 Bruns I, Lucas D, Pinho S, Ahmed J, Lambert M, Kunisaki Y, Scheiermann C, Poncz M, Bergmann A, Frenette P. Megakaryocytes regulate hematopoietic stem cell quiescence via CXCL4 secretion Experimental Hematology. 42: S18. DOI: 10.1016/J.Exphem.2014.07.063  0.429
2013 Manwani D, Frenette PS. Vaso-occlusion in sickle cell disease: pathophysiology and novel targeted therapies. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2013: 362-9. PMID 24319205 DOI: 10.1182/Asheducation-2013.1.362  0.306
2013 Kunisaki Y, Bruns I, Scheiermann C, Ahmed J, Pinho S, Zhang D, Mizoguchi T, Wei Q, Lucas D, Ito K, Mar JC, Bergman A, Frenette PS. Arteriolar niches maintain haematopoietic stem cell quiescence. Nature. 502: 637-43. PMID 24107994 DOI: 10.1038/Nature12612  0.475
2013 Manwani D, Frenette PS. Vaso-occlusion in sickle cell disease: pathophysiology and novel targeted therapies. Blood. 122: 3892-8. PMID 24052549 DOI: 10.1182/Blood-2013-05-498311  0.306
2013 Poulos MG, Guo P, Kofler NM, Pinho S, Gutkin MC, Tikhonova A, Aifantis I, Frenette PS, Kitajewski J, Rafii S, Butler JM. Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis. Cell Reports. 4: 1022-34. PMID 24012753 DOI: 10.1016/J.Celrep.2013.07.048  0.425
2013 Aronovich A, Nur Y, Shezen E, Rosen C, Zlotnikov Klionsky Y, Milman I, Yarimi L, Hagin D, Rechavi G, Martinowitz U, Nagasawa T, Frenette PS, Tchorsh-Yutsis D, Reisner Y. A novel role for factor VIII and thrombin/PAR1 in regulating hematopoiesis and its interplay with the bone structure. Blood. 122: 2562-71. PMID 23982175 DOI: 10.1182/Blood-2012-08-447458  0.468
2013 Pinho S, Lacombe J, Hanoun M, Mizoguchi T, Bruns I, Kunisaki Y, Frenette PS. PDGFRα and CD51 mark human nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion. The Journal of Experimental Medicine. 210: 1351-67. PMID 23776077 DOI: 10.1084/Jem.20122252  0.748
2013 Casanova-Acebes M, Pitaval C, Weiss LA, Nombela-Arrieta C, Chèvre R, A-González N, Kunisaki Y, Zhang D, van Rooijen N, Silberstein LE, Weber C, Nagasawa T, Frenette PS, Castrillo A, Hidalgo A. Rhythmic modulation of the hematopoietic niche through neutrophil clearance. Cell. 153: 1025-35. PMID 23706740 DOI: 10.1016/J.Cell.2013.04.040  0.461
2013 Lucas D, Scheiermann C, Chow A, Kunisaki Y, Bruns I, Barrick C, Tessarollo L, Frenette PS. Chemotherapy-induced bone marrow nerve injury impairs hematopoietic regeneration. Nature Medicine. 19: 695-703. PMID 23644514 DOI: 10.1038/Nm.3155  0.658
2013 Hashimoto D, Chow A, Noizat C, Teo P, Beasley MB, Leboeuf M, Becker CD, See P, Price J, Lucas D, Greter M, Mortha A, Boyer SW, Forsberg EC, Tanaka M, ... ... Frenette PS, et al. Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity. 38: 792-804. PMID 23601688 DOI: 10.1016/J.Immuni.2013.04.004  0.699
2013 Hanoun M, Frenette PS. This niche is a maze; an amazing niche. Cell Stem Cell. 12: 391-2. PMID 23561440 DOI: 10.1016/J.Stem.2013.03.012  0.428
2013 Shi PA, Isola LM, Gabrilove JL, Moshier EL, Godbold JH, Miller LK, Frenette PS. Prospective cohort study of the circadian rhythm pattern in allogeneic sibling donors undergoing standard granulocyte colony-stimulating factor mobilization. Stem Cell Research & Therapy. 4: 30. PMID 23514984 DOI: 10.1186/Scrt180  0.382
2013 Chow A, Huggins M, Ahmed J, Hashimoto D, Lucas D, Kunisaki Y, Pinho S, Leboeuf M, Noizat C, van Rooijen N, Tanaka M, Zhao ZJ, Bergman A, Merad M, Frenette PS. CD169⁺ macrophages provide a niche promoting erythropoiesis under homeostasis and stress. Nature Medicine. 19: 429-36. PMID 23502962 DOI: 10.1038/Nm.3057  0.723
2013 Frenette PS, Pinho S, Lucas D, Scheiermann C. Mesenchymal stem cell: keystone of the hematopoietic stem cell niche and a stepping-stone for regenerative medicine. Annual Review of Immunology. 31: 285-316. PMID 23298209 DOI: 10.1146/Annurev-Immunol-032712-095919  0.473
2013 Bianco P, Cao X, Frenette PS, Mao JJ, Robey PG, Simmons PJ, Wang CY. The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine. Nature Medicine. 19: 35-42. PMID 23296015 DOI: 10.1038/Nm.3028  0.429
2013 Ahmed J, Kunisaki Y, Merad M, Frenette PS. Nestin+ Pericytes In The Fetal Liver Are Necessary To Maintain HSCs Blood. 122: 583-583. DOI: 10.1182/Blood.V122.21.583.583  0.646
2013 Hanoun M, Zhang D, Pinho S, Mizoguchi T, Lacombe J, Armstrong SA, Duehrsen U, Frenette PS. Acute Myeloid Leukemia Alters The Mesenchymal Stem Cell Potential Of The HSC Niche: Evidence For Modulation By β-Adrenergic Signals Blood. 122: 342-342. DOI: 10.1182/Blood.V122.21.342.342  0.767
2013 Zhang D, Kunisaki Y, Frenette PS. Neutrophil Aging, Regulated By Microbiota-Derived Signals, Promotes Sickle Cell Vaso-Occlusion Blood. 122: 324-324. DOI: 10.1182/Blood.V122.21.324.324  0.382
2013 Bruns I, Lucas D, Pinho S, Ahmed J, Lambert MP, Scheiermann C, Kunisaki Y, Poncz M, Frenette PS. Megakaryocytes Regulate Hematopoietic Stem Cell Quiescence Via PF4 Secretion Blood. 122: 3-3. DOI: 10.1182/Blood.V122.21.3.3  0.505
2013 Chen G, Fuchs TA, Wagner DD, Frenette PS. Heme-Induced Neutrophil Extracellular Traps (NETs) Formation Contributes To Sickle Cell Disease Pathogenesis Blood. 122: 184-184. DOI: 10.1182/Blood.V122.21.184.184  0.573
2013 Bruns I, Lucas D, Pinho S, Ahmed J, Kunisaki Y, Scheiermann C, Frenette P. Peri-vascular megakaryocytes restrain hematopoietic stem cell proliferation Experimental Hematology. 41: S12. DOI: 10.1016/J.Exphem.2013.05.045  0.426
2012 Scheiermann C, Kunisaki Y, Lucas D, Chow A, Jang JE, Zhang D, Hashimoto D, Merad M, Frenette PS. Adrenergic nerves govern circadian leukocyte recruitment to tissues. Immunity. 37: 290-301. PMID 22863835 DOI: 10.1016/J.Immuni.2012.05.021  0.806
2012 Almeida CB, Scheiermann C, Jang JE, Prophete C, Costa FF, Conran N, Frenette PS. Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice. Blood. 120: 2879-88. PMID 22833547 DOI: 10.1182/Blood-2012-02-409524  0.737
2012 Miller JC, Brown BD, Shay T, Gautier EL, Jojic V, Cohain A, Pandey G, Leboeuf M, Elpek KG, Helft J, Hashimoto D, Chow A, Price J, Greter M, Bogunovic M, ... ... Frenette PS, et al. Deciphering the transcriptional network of the dendritic cell lineage. Nature Immunology. 13: 888-99. PMID 22797772 DOI: 10.1038/Ni.2370  0.679
2012 Greter M, Helft J, Chow A, Hashimoto D, Mortha A, Agudo-Cantero J, Bogunovic M, Gautier EL, Miller J, Leboeuf M, Lu G, Aloman C, Brown BD, Pollard JW, Xiong H, ... ... Frenette PS, et al. GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells. Immunity. 36: 1031-46. PMID 22749353 DOI: 10.1016/J.Immuni.2012.03.027  0.691
2012 Kunisaki Y, Frenette PS. The secrets of the bone marrow niche: Enigmatic niche brings challenge for HSC expansion. Nature Medicine. 18: 864-5. PMID 22673997 DOI: 10.1038/Nm.2825  0.414
2012 Lucas D, Bruns I, Battista M, Mendez-Ferrer S, Magnon C, Kunisaki Y, Frenette PS. Norepinephrine reuptake inhibition promotes mobilization in mice: potential impact to rescue low stem cell yields. Blood. 119: 3962-5. PMID 22422821 DOI: 10.1182/Blood-2011-07-367102  0.361
2012 Jang JE, Hidalgo A, Frenette PS. Intravenous immunoglobulins modulate neutrophil activation and vascular injury through FcγRIII and SHP-1. Circulation Research. 110: 1057-66. PMID 22415018 DOI: 10.1161/Circresaha.112.266411  0.681
2012 Chow A, Huggins M, Ahmed J, Lucas D, Hashimoto D, Kunisaki Y, Pinho S, Leboeuf M, Noizat C, van Rooijen N, Tanaka M, Zhao ZJ, Bergman A, Merad M, Frenette PS. CD169+ Macrophages Regulate Erythropoiesis Under Homeostasis, Recovery From Erythron Injury and in JAK2V617F-Induced Polycythemia Vera Blood. 120: 80-80. DOI: 10.1182/Blood.V120.21.80.80  0.721
2012 Kunisaki Y, Bruns I, Scheiermann C, Pinho S, Zhang D, Frenette PS. Bone Marrow Arteriolar Niches Maintain Hematopoietic Stem Cell Quiescence Blood. 120: 638-638. DOI: 10.1182/Blood.V120.21.638.638  0.44
2012 Pinho S, Lacombe J, Hanoun M, Bruns I, Kunisaki Y, Mizoguchi T, Frenette PS. PDGFRα and CD51 Mark Human Nestin+ Sphere-Forming Mesenchymal Stem Cells Capable of Robust Hematopoietic Stem Cell Expansion Blood. 120: 505-505. DOI: 10.1182/Blood.V120.21.505.505  0.732
2012 Landau HJ, Bello C, Hoover E, Riedel E, Frenette P, Comenzo RL. Urinary Excretion of Epinephrine and Dopamine Correlates with Efficiency of G-CSF Mobilized Stem Cells in Patients with Al Amyloidosis Biology of Blood and Marrow Transplantation. 18. DOI: 10.1016/J.Bbmt.2011.12.143  0.306
2011 Ferraro F, Lymperi S, Méndez-Ferrer S, Saez B, Spencer JA, Yeap BY, Masselli E, Graiani G, Prezioso L, Rizzini EL, Mangoni M, Rizzoli V, Sykes SM, Lin CP, Frenette PS, et al. Diabetes impairs hematopoietic stem cell mobilization by altering niche function. Science Translational Medicine. 3: 104ra101. PMID 21998408 DOI: 10.1126/Scitranslmed.3002191  0.437
2011 Magnon C, Lucas D, Frenette PS. Trafficking of stem cells. Methods in Molecular Biology (Clifton, N.J.). 750: 3-24. PMID 21618080 DOI: 10.1007/978-1-61779-145-1_1  0.422
2011 Hashimoto D, Chow A, Greter M, Saenger Y, Kwan WH, Leboeuf M, Ginhoux F, Ochando JC, Kunisaki Y, van Rooijen N, Liu C, Teshima T, Heeger PS, Stanley ER, Frenette PS, et al. Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation. The Journal of Experimental Medicine. 208: 1069-82. PMID 21536742 DOI: 10.1084/Jem.20101709  0.699
2011 Dar A, Schajnovitz A, Lapid K, Kalinkovich A, Itkin T, Ludin A, Kao WM, Battista M, Tesio M, Kollet O, Cohen NN, Margalit R, Buss EC, Baleux F, Oishi S, ... ... Frenette PS, et al. Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells. Leukemia. 25: 1286-96. PMID 21494253 DOI: 10.1038/Leu.2011.62  0.813
2011 Shi C, Jia T, Mendez-Ferrer S, Hohl TM, Serbina NV, Lipuma L, Leiner I, Li MO, Frenette PS, Pamer EG. Bone marrow mesenchymal stem and progenitor cells induce monocyte emigration in response to circulating toll-like receptor ligands. Immunity. 34: 590-601. PMID 21458307 DOI: 10.1016/J.Immuni.2011.02.016  0.438
2011 Nácher M, Blázquez AB, Shao B, Matesanz A, Prophete C, Berin MC, Frenette PS, Hidalgo A. Physiological contribution of CD44 as a ligand for E-Selectin during inflammatory T-cell recruitment. The American Journal of Pathology. 178: 2437-46. PMID 21457936 DOI: 10.1016/J.Ajpath.2011.01.039  0.382
2011 Jang JE, Hod EA, Spitalnik SL, Frenette PS. CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions. The Journal of Clinical Investigation. 121: 1397-401. PMID 21383500 DOI: 10.1172/Jci45336  0.723
2011 Chow A, Lucas D, Hidalgo A, Méndez-Ferrer S, Hashimoto D, Scheiermann C, Battista M, Leboeuf M, Prophete C, van Rooijen N, Tanaka M, Merad M, Frenette PS. Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche. The Journal of Experimental Medicine. 208: 261-71. PMID 21282381 DOI: 10.1084/Jem.20101688  0.753
2011 Landau H, Hassoun H, Hoffman JE, Bello C, Hoover E, Riedel E, Frenette PS, Comenzo RL. Urinary Excretion of Epinephrine and Dopamine Correlates with Efficiency of G-CSF Mobilized Stem Cells in Patients with AL Amyloidosis Blood. 118: 316-316. DOI: 10.1182/Blood.V118.21.316.316  0.434
2011 Lucas D, Scheiermann C, Chow A, Kunisaki Y, Barrick C, Tessarollo L, Frenette PS. Bone Marrow Neuropathy Prevents Hematopoietic Regeneration Blood. 118: 139-139. DOI: 10.1182/Blood.V118.21.139.139  0.697
2011 Scheiermann C, Kunisaki Y, Jang J, Zhang D, Chow A, Lucas D, Frenette PS. Local Adrenergic Nerves Regulate Diurnal Leukocyte Adhesion: Impact In Sickle Cell Disease Blood. 118: 1099-1099. DOI: 10.1182/Blood.V118.21.1099.1099  0.641
2011 Dar A, Schajnovitz A, Lapid K, Kalinkovich A, Itkin T, Ludin A, Kao WM, Battista M, Tesio M, Kollet O, Cohen NN, Margalit R, Buss EC, Baleux F, Oishi S, ... ... Frenette PS, et al. Erratum: Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells (Leukemia (April 2011) DOI:10.1038/leu.2011.62) Leukemia. 25. DOI: 10.1038/Leu.2011.132  0.445
2010 Méndez-Ferrer S, Michurina TV, Ferraro F, Mazloom AR, Macarthur BD, Lira SA, Scadden DT, Ma'ayan A, Enikolopov GN, Frenette PS. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature. 466: 829-34. PMID 20703299 DOI: 10.1038/Nature09262  0.471
2010 Chang J, Patton JT, Sarkar A, Ernst B, Magnani JL, Frenette PS. GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice. Blood. 116: 1779-86. PMID 20508165 DOI: 10.1182/Blood-2009-12-260513  0.439
2010 Méndez-Ferrer S, Battista M, Frenette PS. Cooperation of beta(2)- and beta(3)-adrenergic receptors in hematopoietic progenitor cell mobilization. Annals of the New York Academy of Sciences. 1192: 139-44. PMID 20392229 DOI: 10.1111/J.1749-6632.2010.05390.X  0.349
2010 Scheiermann C, Kunisaki Y, Jang JE, Frenette PS. Neutrophil microdomains: linking heterocellular interactions with vascular injury. Current Opinion in Hematology. 17: 25-30. PMID 19923987 DOI: 10.1097/Moh.0B013E328333D2A3  0.726
2010 Kunisaki Y, Scheiermann C, Lucas D, Chow A, Frenette PS. Circadian Adrenergic Regulation of Bone Marrow Endothelial Adhesion Molecule Expression Impacts Progenitor Recruitment and Engraftment Efficiency Blood. 116: 398-398. DOI: 10.1182/Blood.V116.21.398.398  0.686
2010 Chen Y, Zeng Z, Shi Y, Jacamo R, Ludin C, Dembowsky K, Frenette PS, Konopleva M, Andreeff M. Targeting CXCR4, SDF1 and Beta-Adrenergic Receptors In the AML Microenvironment by Novel Antagonist POL6326, G-CSF and Isoproterenol Blood. 116: 2179-2179. DOI: 10.1182/Blood.V116.21.2179.2179  0.465
2009 Méndez-Ferrer S, Frenette PS. Galpha(s) uncouples hematopoietic stem cell homing and mobilization. Cell Stem Cell. 4: 379-80. PMID 19427288 DOI: 10.1016/J.Stem.2009.04.009  0.412
2009 Méndez-Ferrer S, Chow A, Merad M, Frenette PS. Circadian rhythms influence hematopoietic stem cells. Current Opinion in Hematology. 16: 235-42. PMID 19417648 DOI: 10.1097/Moh.0B013E32832Bd0F5  0.731
2009 Hidalgo A, Chang J, Jang JE, Peired AJ, Chiang EY, Frenette PS. Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury. Nature Medicine. 15: 384-91. PMID 19305412 DOI: 10.1038/Nm.1939  0.69
2009 Frenette PS, Méndez-Ferrer S, Lucas-Alcaraz D, Batista M, Lira S, Michurina TV, Enikolopov GN. The Hematopoietic Stem Cell Niche. Blood. 114: SCI-49-SCI-49. DOI: 10.1182/Blood.V114.22.Sci-49.Sci-49  0.486
2009 Méndez-Ferrer S, Michurina TV, Ferraro F, Mazloom A, MacArthur B, Lira S, Scadden DT, Ma'ayan A, Enikolopov GN, Frenette PS. Coordinated Regulation of Hematopoietic and Mesenchymal Stem Cells in a Bone Marrow Niche. Blood. 114: 2-2. DOI: 10.1182/Blood.V114.22.2.2  0.502
2008 Lucas D, Battista M, Shi PA, Isola L, Frenette PS. Mobilized hematopoietic stem cell yield depends on species-specific circadian timing. Cell Stem Cell. 3: 364-6. PMID 18940728 DOI: 10.1182/Blood.V112.11.3494.3494  0.406
2008 Lucas D, Frenette PS. Osteoblasts: yes, they can. Blood. 112: 455. PMID 18650456 DOI: 10.1182/Blood-2008-05-158758  0.44
2008 Wagner DD, Frenette PS. The vessel wall and its interactions. Blood. 111: 5271-81. PMID 18502843 DOI: 10.1182/Blood-2008-01-078204  0.542
2008 Méndez-Ferrer S, Lucas D, Battista M, Frenette PS. Haematopoietic stem cell release is regulated by circadian oscillations. Nature. 452: 442-7. PMID 18256599 DOI: 10.1038/Nature06685  0.44
2008 Chang J, Shi PA, Chiang EY, Frenette PS. Intravenous immunoglobulins reverse acute vaso-occlusive crises in sickle cell mice through rapid inhibition of neutrophil adhesion. Blood. 111: 915-23. PMID 17932253 DOI: 10.1182/Blood-2007-04-084061  0.422
2008 Frenette PS, Hidalgo A, Chang J, Peired A. Contributions of Immune Cells to Vascular Occlusion in Sickle Cell Disease. Blood. 112: sci-44-sci-44. DOI: 10.1182/Blood.V112.11.Sci-44.Sci-44  0.452
2008 Migliaccio G, Sanchez M, Masiello F, Tirelli V, Iliecic K, Mancini A, Frenette PS, Migliaccio AR. Dynamic Pattern of Adhesion Receptor Expression during the Maturation of Ex-Vivo Generated Human Adult and Neonatal Erythroid Cells. Blood. 112: 997-997. DOI: 10.1182/Blood.V112.11.997.997  0.396
2008 Kunisaki Y, Lucas D, Frenette PS. Circadian Expression of Endothelial Selectins, Regulated by the Sympathetic Nervous System, Controls Peripheral Leukocyte Homeostasis Blood. 112: 548-548. DOI: 10.1182/Blood.V112.11.548.548  0.339
2008 Chang J, Patton JT, Frenette PS, Magnani JL. Effects of Pan-Selectin Antagonist GMI-1070 on the Treatment of Vaso-Occlusion in Sickle Cell Mice Blood. 112: 535-535. DOI: 10.1182/Blood.V112.11.535.535  0.447
2008 Mendez-Ferrer S, Enikolopov GN, Lira S, Frenette PS. Mesenchymal Stem Cells, Regulated by the Sympathetic Nervous System, Form the Hematopoietic Stem Cell Niche Blood. 112: 4-4. DOI: 10.1182/Blood.V112.11.4.4  0.507
2008 Hidalgo A, Frenette PS. Transfusion-Related Acute Lung Injury (TRALI) Requires Heterotypic Interactions of Platelets with Specific Neutrophil Microdomains Blood. 112: 288-288. DOI: 10.1182/Blood.V112.11.288.288  0.387
2008 Battista M, Mendez-Ferrer S, Frenette PS. Granulocyte Colony-Stimulating Factor (G-CSF) Stimulates Sympathetic Nervous System Activity in the Bone Marrow Blood. 112: 2419-2419. DOI: 10.1182/Blood.V112.11.2419.2419  0.367
2008 Lucas D, Frenette PS. The Sympathetic Nervous System Regulates Hematopoietic Stem and Progenitor Cell Homing and Engraftment. Blood. 112: 1387-1387. DOI: 10.1182/Blood.V112.11.1387.1387  0.5
2008 Jang J, Frenette PS. A New Model of Acute Sickle Cell Vaso-Occlusion Elicited by IgGMediated Hemolytic Transfusion Reactions Blood. 112: 122-122. DOI: 10.1182/Blood.V112.11.122.122  0.408
2007 Méndez-Ferrer S, Frenette PS. Hematopoietic stem cell trafficking: regulated adhesion and attraction to bone marrow microenvironment. Annals of the New York Academy of Sciences. 1116: 392-413. PMID 18083941 DOI: 10.1196/Annals.1402.086  0.477
2007 Hidalgo A, Frenette PS. Leukocyte podosomes sense their way through the endothelium. Immunity. 26: 753-5. PMID 17582348 DOI: 10.1016/J.Immuni.2007.06.002  0.348
2007 Hidalgo A, Peired AJ, Wild MK, Vestweber D, Frenette PS. Complete identification of E-selectin ligands on neutrophils reveals distinct functions of PSGL-1, ESL-1, and CD44. Immunity. 26: 477-89. PMID 17442598 DOI: 10.1016/J.Immuni.2007.03.011  0.329
2007 Chiang EY, Hidalgo A, Chang J, Frenette PS. Imaging receptor microdomains on leukocyte subsets in live mice. Nature Methods. 4: 219-22. PMID 17322889 DOI: 10.1038/Nmeth1018  0.362
2007 Magnani JL, Sarkar A, Li Y, Goon S, Wagner B, Chang J, Ernst B, Frenette PS, Patton JT. GMI-1070: A Small Pan-Selectin Antagonist That Inhibits Leukocyte Adhesion and Migration in Multple Disease Models In Vivo. Blood. 110: 2410-2410. DOI: 10.1182/Blood.V110.11.2410.2410  0.437
2007 Chang J, Patton J, Sarkar A, Magnani JL, Frenette PS. A Novel Selectin Antagonist, GMI-1070, Prevents Vaso-Occlusion in Sickle Cell Mice by Inhibiting Leukocyte Adhesion and Activation. Blood. 110: 2245-2245. DOI: 10.1182/Blood.V110.11.2245.2245  0.375
2007 Mendez-Ferrer S, Lucas D, Battista M, Jang J, Frenette P. Circadian Traffic of Hematopoietic Stem Cells Is Orchestrated by the Molecular Clock and Mediated by β3 Adrenergic Signals from the Sympathetic Nervous System. Blood. 110: 219-219. DOI: 10.1182/Blood.V110.11.219.219  0.443
2007 Hidalgo A, Chang J, Peired AJ, Chiang EY, Frenette PS. Sickle Cell Vaso-Occlusion Is Triggered by E-Selectin Ligand Signaling and Propagated by the Leukocyte Integrin Mac-1. Blood. 110: 145-145. DOI: 10.1182/Blood.V110.11.145.145  0.426
2006 Bogunovic M, Ginhoux F, Wagers A, Loubeau M, Isola LM, Lubrano L, Najfeld V, Phelps RG, Grosskreutz C, Scigliano E, Frenette PS, Merad M. Identification of a radio-resistant and cycling dermal dendritic cell population in mice and men. The Journal of Experimental Medicine. 203: 2627-38. PMID 17116734 DOI: 10.1084/Jem.20060667  0.584
2006 Angeli V, Ginhoux F, Llodrà J, Quemeneur L, Frenette PS, Skobe M, Jessberger R, Merad M, Randolph GJ. B cell-driven lymphangiogenesis in inflamed lymph nodes enhances dendritic cell mobilization. Immunity. 24: 203-15. PMID 16473832 DOI: 10.1016/J.Immuni.2006.01.003  0.489
2006 Katayama Y, Battista M, Kao WM, Hidalgo A, Peired AJ, Thomas SA, Frenette PS. Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell. 124: 407-21. PMID 16439213 DOI: 10.1016/J.Cell.2005.10.041  0.82
2006 Hidalgo A, Peired AJ, Frenette PS. ESL-1 Is a Major Physiological Leukocyte Ligand for E-Selectin That Cooperates with PSGL-1 and CD44, and Together Mediate All Binding Activity to Endothelial Selectins In Vivo. Blood. 108: 1787-1787. DOI: 10.1182/Blood.V108.11.1787.1787  0.405
2006 Chiang EY, Hidalgo A, Chang J, Frenette PS. Real-Time Identification of Leukocyte Subsets and Cell Surface Receptor Microdomains in the Microvasculature of Wild-Type and Sickle Cell Mice In Vivo. Blood. 108: 1229-1229. DOI: 10.1182/Blood.V108.11.1229.1229  0.423
2006 Angeli V, Ginhoux F, Llodrà J, Quemeneur L, Frenette PS, Skobe M, Jessberger R, Merad M, Randolph GJ. B Cell-Driven Lymphangiogenesis in Inflamed Lymph Nodes Enhances Dendritic Cell Mobilization Immunity. 25: 689. DOI: 10.1016/J.Immuni.2006.10.002  0.506
2005 Chiang EY, Frenette PS. Sickle cell vaso-occlusion. Hematology/Oncology Clinics of North America. 19: 771-84, v. PMID 16214643 DOI: 10.1016/J.Hoc.2005.08.002  0.388
2005 Katayama Y, Hidalgo A, Chang J, Peired A, Frenette PS. CD44 is a physiological E-selectin ligand on neutrophils. The Journal of Experimental Medicine. 201: 1183-9. PMID 15824084 DOI: 10.1084/Jem.20042014  0.37
2005 Hidalgo A, Frenette PS. Enforced fucosylation of neonatal CD34+ cells generates selectin ligands that enhance the initial interactions with microvessels but not homing to bone marrow. Blood. 105: 567-75. PMID 15367439 DOI: 10.1182/Blood-2004-03-1026  0.457
2005 Merad M, Angeli V, Tacke F, Bogunovic M, Frenette PS, Randolph GJ, Ginhoux F. Identification of the Circulating Langerhans Cell Precursor. Blood. 106: 634-634. DOI: 10.1182/Blood.V106.11.634.634  0.545
2005 Bogunovic M, Chicha L, Isola L, Ginhoux F, Frenette PS, Manz MG, Miriam M. Homeostasis of Human Langerhans Cells after Allogeneic Hematopoietic Stem Cell Transplantation. Blood. 106: 3092-3092. DOI: 10.1182/Blood.V106.11.3092.3092  0.369
2004 Martin AP, Coronel EC, Sano G, Chen SC, Vassileva G, Canasto-Chibuque C, Sedgwick JD, Frenette PS, Lipp M, Furtado GC, Lira SA. A novel model for lymphocytic infiltration of the thyroid gland generated by transgenic expression of the CC chemokine CCL21. Journal of Immunology (Baltimore, Md. : 1950). 173: 4791-8. PMID 15470018 DOI: 10.4049/Jimmunol.173.8.4791  0.346
2004 Frenette PS. Sickle cell vasoocclusion: heterotypic, multicellular aggregations driven by leukocyte adhesion. Microcirculation (New York, N.Y. : 1994). 11: 167-77. PMID 15280090 DOI: 10.1080/10739680490278556  0.43
2004 Katayama Y, Hidalgo A, Peired A, Frenette PS. Integrin alpha4beta7 and its counterreceptor MAdCAM-1 contribute to hematopoietic progenitor recruitment into bone marrow following transplantation. Blood. 104: 2020-6. PMID 15161666 DOI: 10.1182/Blood-2003-12-4157  0.484
2004 Hidalgo A, Peired AJ, Weiss LA, Katayama Y, Frenette PS. The integrin alphaMbeta2 anchors hematopoietic progenitors in the bone marrow during enforced mobilization. Blood. 104: 993-1001. PMID 15100152 DOI: 10.1182/Blood-2003-10-3702  0.496
2004 Turhan A, Jenab P, Bruhns P, Ravetch JV, Coller BS, Frenette PS. Intravenous immune globulin prevents venular vaso-occlusion in sickle cell mice by inhibiting leukocyte adhesion and the interactions between sickle erythrocytes and adherent leukocytes. Blood. 103: 2397-400. PMID 14630831 DOI: 10.1182/Blood-2003-07-2209  0.433
2004 Katayama Y, Hidalgo A, Frenette PS. Galactocerebrosides, Essential for Hematopoietic Progenitor Mobilization, Regulate SDF-1 (CXCL12)-Mediated Attraction to Bone. Blood. 104: 665-665. DOI: 10.1182/Blood.V104.11.665.665  0.43
2004 Frenette PS. P-selectin and VWF tie the knot Blood. 103: 1979-1980. DOI: 10.1182/Blood-2004-01-0073  0.366
2003 Frenette J, Chbinou N, Godbout C, Marsolais D, Frenette PS. Macrophages, not neutrophils, infiltrate skeletal muscle in mice deficient in P/E selectins after mechanical reloading. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 285: R727-32. PMID 12829442 DOI: 10.1152/Ajpregu.00175.2003  0.315
2003 Katayama Y, Frenette PS. Galactocerebrosides are required postnatally for stromal-dependent bone marrow lymphopoiesis. Immunity. 18: 789-800. PMID 12818160 DOI: 10.1016/S1074-7613(03)00150-X  0.432
2003 Katayama Y, Hidalgo A, Furie BC, Vestweber D, Furie B, Frenette PS. PSGL-1 participates in E-selectin-mediated progenitor homing to bone marrow: evidence for cooperation between E-selectin ligands and alpha4 integrin. Blood. 102: 2060-7. PMID 12763924 DOI: 10.1182/Blood-2003-04-1212  0.389
2002 Hidalgo A, Weiss LA, Frenette PS. Functional selectin ligands mediating human CD34(+) cell interactions with bone marrow endothelium are enhanced postnatally. The Journal of Clinical Investigation. 110: 559-69. PMID 12189250 DOI: 10.1172/Jci0214047  0.436
2002 Turhan A, Weiss LA, Mohandas N, Coller BS, Frenette PS. Primary role for adherent leukocytes in sickle cell vascular occlusion: a new paradigm. Proceedings of the National Academy of Sciences of the United States of America. 99: 3047-51. PMID 11880644 DOI: 10.1073/Pnas.052522799  0.434
2002 Frenette PS. Sickle cell vaso-occlusion: multistep and multicellular paradigm. Current Opinion in Hematology. 9: 101-6. PMID 11844991 DOI: 10.1097/00062752-200203000-00003  0.421
2002 Frenette PS. Phages that display P-selectin antagonism Blood. 100: 3443-3444. DOI: 10.1182/Blood-2002-09-2919  0.368
2000 Frenette PS, Denis CV, Weiss L, Jurk K, Subbarao S, Kehrel B, Hartwig JH, Vestweber D, Wagner DD. P-Selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo. The Journal of Experimental Medicine. 191: 1413-22. PMID 10770806 DOI: 10.1084/Jem.191.8.1413  0.529
2000 Frenette PS, Weiss L. Sulfated glycans induce rapid hematopoietic progenitor cell mobilization: evidence for selectin-dependent and independent mechanisms Blood. 96: 2460-2468. DOI: 10.1182/Blood.V96.7.2460.H8002460_2460_2468  0.466
1999 Robinson SD, Frenette PS, Rayburn H, Cummiskey M, Ullman-Culleré M, Wagner DD, Hynes RO. Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment. Proceedings of the National Academy of Sciences of the United States of America. 96: 11452-7. PMID 10500197 DOI: 10.1073/Pnas.96.20.11452  0.56
1999 Enjyoji K, Sévigny J, Lin Y, Frenette PS, Christie PD, Esch JS, Imai M, Edelberg JM, Rayburn H, Lech M, Beeler DL, Csizmadia E, Wagner DD, Robson SC, Rosenberg RD. Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation. Nature Medicine. 5: 1010-7. PMID 10470077 DOI: 10.1038/12447  0.555
1999 Soriano SG, Wang YF, Wagner DD, Frenette PS. P- and E-selectin-deficient mice are susceptible to cerebral ischemia-reperfusion injury. Brain Research. 835: 360-4. PMID 10415396 DOI: 10.1016/S0006-8993(99)01637-6  0.512
1998 Frenette PS, Subbarao S, Mazo IB, von Andrian UH, Wagner DD. Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow. Proceedings of the National Academy of Sciences of the United States of America. 95: 14423-8. PMID 9826716 DOI: 10.1073/Pnas.95.24.14423  0.623
1998 Hartwell DW, Mayadas TN, Berger G, Frenette PS, Rayburn H, Hynes RO, Wagner DD. Role of P-selectin cytoplasmic domain in granular targeting in vivo and in early inflammatory responses. The Journal of Cell Biology. 143: 1129-41. PMID 9817767 DOI: 10.1083/Jcb.143.4.1129  0.587
1998 Hartwell DW, Butterfield CE, Frenette PS, Kenyon BM, Hynes RO, Folkman J, Wagner DD. Angiogenesis in P- and E-selectin-deficient mice. Microcirculation (New York, N.Y. : 1994). 5: 173-8. PMID 9789257 DOI: 10.1111/J.1549-8719.1998.Tb00066.X  0.571
1998 Homeister JW, Zhang M, Frenette PS, Hynes RO, Wagner DD, Lowe JB, Marks RM. Overlapping functions of E- and P-selectin in neutrophil recruitment during acute inflammation. Blood. 92: 2345-52. PMID 9746773 DOI: 10.1182/Blood.V92.7.2345.2345_2345_2352  0.566
1998 Seiler KP, Ma Y, Weis JH, Frenette PS, Hynes RO, Wagner DD, Weis JJ. E and P selectins are not required for resistance to severe murine lyme arthritis. Infection and Immunity. 66: 4557-9. PMID 9712820 DOI: 10.1128/Iai.66.9.4557-4559.1998  0.557
1998 Denis C, Methia N, Frenette PS, Rayburn H, Ullman-Culleré M, Hynes RO, Wagner DD. A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. Proceedings of the National Academy of Sciences of the United States of America. 95: 9524-9. PMID 9689113 DOI: 10.1073/Pnas.95.16.9524  0.56
1998 Mazo IB, Gutierrez-Ramos JC, Frenette PS, Hynes RO, Wagner DD, von Andrian UH. Hematopoietic progenitor cell rolling in bone marrow microvessels: parallel contributions by endothelial selectins and vascular cell adhesion molecule 1. The Journal of Experimental Medicine. 188: 465-74. PMID 9687524 DOI: 10.1084/Jem.188.3.465  0.647
1998 Dong ZM, Chapman SM, Brown AA, Frenette PS, Hynes RO, Wagner DD. The combined role of P- and E-selectins in atherosclerosis. The Journal of Clinical Investigation. 102: 145-52. PMID 9649568 DOI: 10.1172/Jci3001  0.53
1998 Frenette PS, Moyna C, Hartwell DW, Lowe JB, Hynes RO, Wagner DD. Platelet-endothelial interactions in inflamed mesenteric venules. Blood. 91: 1318-24. PMID 9454762 DOI: 10.1182/Blood.V91.4.1318  0.585
1998 Seiler KP, Ma Y, Weis JH, Frenette PS, Hynes RO, Wagner DD, Weis JJ. E and P Selectins Are Not Required for Resistance to Severe Murine Lyme Arthritis Infection and Immunity. 66: 4557-4559. DOI: 10.1128/iai.66.9.4557-4559.1998  0.503
1997 Weiser MR, Pechet TT, Williams JP, Ma M, Frenette PS, Moore FD, Kobzik L, Hines RO, Wagner DD, Carroll MC, Hechtman HB. Experimental murine acid aspiration injury is mediated by neutrophils and the alternative complement pathway. Journal of Applied Physiology (Bethesda, Md. : 1985). 83: 1090-5. PMID 9338415 DOI: 10.1152/Jappl.1997.83.4.1090  0.514
1997 Walter UM, Ayer LM, Manning AM, Frenette PS, Wagner DD, Hynes RO, Wolitzky BA, Issekutz AC. Generation and characterization of a novel adhesion function blocking monoclonal antibody recognizing both rat and mouse E-selectin. Hybridoma. 16: 355-61. PMID 9309426 DOI: 10.1089/Hyb.1997.16.355  0.536
1997 Frenette PS, Wagner DD. Insights into Selectin Function from Knockout Mice Thrombosis and Haemostasis. 78: 060-064. DOI: 10.1055/S-0038-1657501  0.596
1996 Frenette PS, Mayadas TN, Rayburn H, Hynes RO, Wagner DD. Double knockout highlights value of endothelial selectins. Immunology Today. 17: 205. PMID 8991376 DOI: 10.1016/0167-5699(96)80555-X  0.5
1996 Tang T, Frenette PS, Hynes RO, Wagner DD, Mayadas TN. Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins. The Journal of Clinical Investigation. 97: 2485-90. PMID 8647940 DOI: 10.1172/Jci118695  0.575
1996 Frenette PS, Wagner DD. Adhesion molecules--Part II: Blood vessels and blood cells. The New England Journal of Medicine. 335: 43-5. PMID 8637541 DOI: 10.1056/Nejm199607043350108  0.583
1996 Frenette PS, Wagner DD. Adhesion molecules--Part 1. The New England Journal of Medicine. 334: 1526-9. PMID 8618609 DOI: 10.1056/Nejm199606063342308  0.466
1996 Subramaniam M, Frenette PS, Saffaripour S, Johnson RC, Hynes RO, Wagner DD. Defects in hemostasis in P-selectin-deficient mice. Blood. 87: 1238-42. PMID 8608210 DOI: 10.1182/Blood.V87.4.1238.Bloodjournal8741238  0.571
1996 Frenette PS, Mayadas TN, Rayburn H, Hynes RO, Wagner DD. Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins. Cell. 84: 563-74. PMID 8598043 DOI: 10.1016/S0092-8674(00)81032-6  0.589
1995 Frenette PS, Johnson RC, Hynes RO, Wagner DD. Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin. Proceedings of the National Academy of Sciences of the United States of America. 92: 7450-4. PMID 7543682 DOI: 10.1073/Pnas.92.16.7450  0.556
1995 Johnson R, Mayadas T, Frenette P, Mebius R, Subramaniam M, Lacasce A, Hynes R, Wagner D. Blood cell dynamics in P-selectin-deficient mice Blood. 86: 1106-1114. DOI: 10.1182/Blood.V86.3.1106.Bloodjournal8631106  0.622
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