Alexander S.S. Dömling - Publications

Affiliations: 
University of Groningen, Groningen, Netherlands 
Area:
Drug Design
Website:
http://hoogleraren.ub.rug.nl/?page=showPerson&type=hoogleraar&hoogleraar_id=2262

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Li J, Zheng Q, Dömling A. Exploring Phthalimide as the Acid Component in the Passerini Reaction. Organic Letters. PMID 38227542 DOI: 10.1021/acs.orglett.3c03962  0.492
2023 Patil P, Zheng Q, Kurpiewsk K, Dömling A. The isocyanide S2 reaction. Nature Communications. 14: 5807. PMID 37726293 DOI: 10.1038/s41467-023-41253-2  0.446
2023 Li X, Romero MD, Tcaturian S, Kurpiewska K, Dömling A. -Edited Guanine Isosteres. The Journal of Organic Chemistry. PMID 37431831 DOI: 10.1021/acs.joc.3c00467  0.429
2023 Gao L, Shaabani S, Reyes Romero A, Xu R, Ahmadianmoghaddam M, Dömling A. 'Chemistry at the speed of sound': automated 1536-well nanoscale synthesis of 16 scaffolds in parallel. Green Chemistry : An International Journal and Green Chemistry Resource : Gc. 25: 1380-1394. PMID 36824604 DOI: 10.1039/d2gc04312b  0.388
2022 Li X, Wang Q, Zheng Q, Kurpiewska K, Kalinowska-Tluscik J, Dömling A. Access to Isoquinolin-2(1)-yl-acetamides and Isoindolin-2-yl-acetamides from a Common MCR Precursor. The Journal of Organic Chemistry. PMID 36282152 DOI: 10.1021/acs.joc.2c01905  0.447
2022 Xu R, Wang Z, Zheng Q, Patil P, Dömling A. . The Journal of Organic Chemistry. PMID 36095044 DOI: 10.1021/acs.joc.2c01561  0.456
2022 Iordanidou D, Kallitsakis MG, Tzani MA, Ioannou DI, Zarganes-Tzitzikas T, Neochoritis CG, Dömling A, Terzidis MA, Lykakis IN. Supported Gold Nanoparticle-Catalyzed Selective Reduction of Multifunctional, Aromatic Nitro Precursors into Amines and Synthesis of 3,4-Dihydroquinoxalin-2-Ones. Molecules (Basel, Switzerland). 27. PMID 35889270 DOI: 10.3390/molecules27144395  0.359
2022 Dömling A. Innovations and Inventions: Why Was the Ugi Reaction Discovered Only 37 Years after the Passerini Reaction? The Journal of Organic Chemistry. PMID 35881912 DOI: 10.1021/acs.joc.2c00792  0.377
2022 Zheng Q, Li X, Kurpiewska K, Dömling A. Synthesis of Tunable Fluorescent Imidazole-Fused Heterocycle Dimers. Organic Letters. PMID 35830622 DOI: 10.1021/acs.orglett.2c01642  0.309
2022 Zhang B, Kurpiewska K, Dömling A. Highly Stereoselective Ugi/Pictet-Spengler Sequence. The Journal of Organic Chemistry. 87: 7085-7096. PMID 35549475 DOI: 10.1021/acs.joc.2c00244  0.474
2021 Wang Q, Mgimpatsang KC, Li X, Dömling A. Isoquinolone-4-Carboxylic Acids by Ammonia-Ugi-4CR and Copper-Catalyzed Domino Reaction. The Journal of Organic Chemistry. PMID 34184894 DOI: 10.1021/acs.joc.1c01170  0.456
2021 Lei X, Lampiri P, Patil P, Angeli G, Neochoritis CG, Dömling A. A multicomponent tetrazolo indole synthesis. Chemical Communications (Cambridge, England). PMID 34128009 DOI: 10.1039/d1cc02384e  0.502
2021 Gao K, Shaabani S, Xu R, Zarganes-Tzitzikas T, Gao L, Ahmadianmoghaddam M, Groves MR, Dömling A. Nanoscale, automated, high throughput synthesis and screening for the accelerated discovery of protein modifiers. Rsc Medicinal Chemistry. 12: 809-818. PMID 34124680 DOI: 10.1039/d1md00087j  0.308
2021 Sutanto F, Shaabani S, Neochoritis CG, Zarganes-Tzitzikas T, Patil P, Ghonchepour E, Dömling A. Multicomponent reaction-derived covalent inhibitor space. Science Advances. 7. PMID 33536213 DOI: 10.1126/sciadv.abd9307  0.49
2020 Neochoritis CG, Zarganes-Tzitzikas T, Katsampoxaki-Hodgetts K, Dömling A. Multicomponent Reactions: "Kinderleicht". Journal of Chemical Education. 97: 3739-3745. PMID 33071311 DOI: 10.1021/acs.jchemed.0c00290  0.346
2020 Wang Q, Tuinhof J, Mgimpatsang KC, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. Copper-Catalyzed Modular Assembly of Polyheterocycles. The Journal of Organic Chemistry. PMID 32615764 DOI: 10.1021/acs.joc.0c01238  0.32
2020 Vishwanatha TM, Giepmans B, Goda SK, Dömling A. Tubulysin Synthesis Featuring Stereoselective Catalysis and Highly Convergent Multicomponent Assembly. Organic Letters. 22: 5396-5400. PMID 32584589 DOI: 10.1021/acs.orglett.0c01718  0.407
2020 Li J, Di Lorenzo V, Patil P, Ruiz Moreno AJ, Kurpiewska K, Kalinowska-Tłuścik J, Velasco-Velázquez MA, Dömling A. Scaffolding-induced property modulation of chemical space. Acs Combinatorial Science. PMID 32441919 DOI: 10.1021/acscombsci.0c00072  0.411
2020 Konstantinidou M, Magari F, Sutanto F, Haupenthal J, Jumde VR, Ünver MY, Heine A, Camacho CJ, Hirsch AKH, Klebe G, Dömling A. Rapid Discovery of Aspartyl Protease Inhibitors Using an Anchoring Approach. Chemmedchem. PMID 32187447 DOI: 10.1002/Cmdc.202000024  0.3
2020 Abdelraheem EMM, Goodwin I, Shaabani S, de Haan MP, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. 'Atypical Ugi' tetrazoles. Chemical Communications (Cambridge, England). 56: 1799-1802. PMID 31950120 DOI: 10.1039/c9cc09194g  0.333
2019 Boltjes A, Dömling A. The Groebke-Blackburn-Bienaymé Reaction. European Journal of Chemistry (Print). 2019: 7007-7049. PMID 34012704 DOI: 10.1002/ejoc.201901124  0.403
2019 Neochoritis CG, Zarganes-Tzitzikas T, Novotná M, Mitríková T, Wang Z, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. Isocyanide-Based Multicomponent Reactions of Free Phenylboronic Acids. European Journal of Chemistry (Print). 2019: 6132-6137. PMID 33981465 DOI: 10.1002/ejoc.201901187  0.4
2019 Rudick JG, Shaabani S, Dömling A. Editorial: Isocyanide-Based Multicomponent Reactions. Frontiers in Chemistry. 7: 918. PMID 32010668 DOI: 10.3389/Fchem.2019.00918  0.363
2019 Wang Q, Mgimpatsang KC, Konstantinidou M, Shishkina SV, Dömling A. 1,3,4-Oxadiazoles by Ugi-Tetrazole and Huisgen Reaction. Organic Letters. PMID 31478379 DOI: 10.1021/acs.orglett.9b02614  0.371
2019 Kunig VBK, Ehrt C, Dömling A, Brunschweiger A. Isocyanide Multicomponent Reactions on Solid-Phase-Coupled DNA Oligonucleotides for Encoded Library Synthesis. Organic Letters. 21: 7238-7243. PMID 31464126 DOI: 10.1021/acs.orglett.9b02448  0.342
2019 Wang Q, Osipyan A, Konstantinidou M, Butera R, Mgimpatsang KC, Shishkina SV, Dömling A. Pd-catalyzed De Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles. The Journal of Organic Chemistry. PMID 31433186 DOI: 10.1021/acs.joc.9b01258  0.396
2019 Neochoritis CG, Shaabani S, Ahmadianmoghaddam M, Zarganes-Tzitzikas T, Gao L, Novotná M, Mitríková T, Romero AR, Irianti MI, Xu R, Olechno J, Ellson R, Helan V, Kossenjans M, Groves MR, et al. Rapid approach to complex boronic acids. Science Advances. 5: eaaw4607. PMID 31281893 DOI: 10.1126/sciadv.aaw4607  0.458
2019 Wang Y, Patil P, Kurpiewska K, Kalinowska-Tluscik J, Dömling A. Diverse Isoquinoline Scaffolds by Ugi/Pomeranz-Fritsch and Ugi/Schlittler-Müller Reactions. Organic Letters. PMID 31033297 DOI: 10.1021/acs.orglett.9b00778  0.488
2019 Wang Y, Shaabani S, Ahmadianmoghaddam M, Gao L, Xu R, Kurpiewska K, Kalinowska-Tluscik J, Olechno J, Ellson R, Kossenjans M, Helan V, Groves M, Dömling A. Acoustic Droplet Ejection Enabled Automated Reaction Scouting. Acs Central Science. 5: 451-457. PMID 30937372 DOI: 10.1021/acscentsci.8b00782  0.395
2019 Zarganes-Tzitzikas T, Neochoritis CG, Dömling A. Atorvastatin (Lipitor) by MCR. Acs Medicinal Chemistry Letters. 10: 389-392. PMID 30891146 DOI: 10.1021/acsmedchemlett.8b00579  0.383
2019 Neochoritis CG, Kazemi Miraki M, Abdelraheem EMM, Surmiak E, Zarganes-Tzitzikas T, Łabuzek B, Holak TA, Dömling A. Design of indole- and MCR-based macrocycles as p53-MDM2 antagonists. Beilstein Journal of Organic Chemistry. 15: 513-520. PMID 30873235 DOI: 10.3762/bjoc.15.45  0.338
2019 Neochoritis CG, Zhao T, Dömling A. Tetrazoles via Multicomponent Reactions. Chemical Reviews. 119: 1970-2042. PMID 30707567 DOI: 10.1021/acs.chemrev.8b00564  0.367
2019 Shaabani S, Xu R, Ahmadianmoghaddam M, Gao L, Stahorsky M, Olechno J, Ellson R, Kossenjans M, Helan V, Dömling A. Automated and Accelerated Synthesis of Indole Derivatives on a Nano-Scale. Green Chemistry : An International Journal and Green Chemistry Resource : Gc. 21: 225-232. PMID 30686932 DOI: 10.1039/C8GC03039A  0.483
2018 Madhavachary R, Naveen N, Wang Y, Wang Q, Konstantinidou M, Dömling A. β-Carbolinone Analogues from the Ugi Silver Mine. European Journal of Organic Chemistry. 2018: 3139-3143. PMID 31440115 DOI: 10.1002/ejoc.201800557  0.631
2018 Abdelraheem EMM, Khaksar S, Dömling A. Concise Synthesis of Macrocycles by Multicomponent Reactions. Synthesis. 50: 1027-1038. PMID 31439965 DOI: 10.1055/s-0036-1590946  0.481
2018 Iordanidou D, Zarganes-Tzitzikas T, Neochoritis CG, Dömling A, Lykakis IN. Application of Silver Nanoparticles in the Multicomponent Reaction Domain: A Combined Catalytic Reduction Methodology to Efficiently Access Potential Hypertension or Inflammation Inhibitors. Acs Omega. 3: 16005-16013. PMID 30533584 DOI: 10.1021/acsomega.8b02749  0.404
2018 Abdelraheem EMM, Shaabani S, Dömling A. Macrocycles: MCR synthesis and applications in drug discovery. Drug Discovery Today. Technologies. 29: 11-17. PMID 30471668 DOI: 10.1016/j.ddtec.2018.06.008  0.367
2018 Shaabani S, Dömling A. The Catalytic Enantioselective Ugi Four-Component Reactions. Angewandte Chemie (International Ed. in English). 57: 16266-16268. PMID 30431219 DOI: 10.1002/anie.201811129  0.408
2018 Kurhade S, Diekstra E, Sutanto F, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. Multicomponent Reaction Based Synthesis of 1-Tetrazolylimidazo[1,5- a]pyridines. Organic Letters. 20: 3871-3874. PMID 29943994 DOI: 10.1021/acs.orglett.8b01452  0.521
2018 Madhavachary R, Zarganes-Tzitzikas T, Patil P, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. Synthesis of highly substituted imidazole Uracil containing molecules via Ugi-4CR and Passerini-3CR. Acs Combinatorial Science. PMID 29457887 DOI: 10.1021/acscombsci.7b00145  0.688
2018 Abdelraheem EMM, Khaksar S, Kurpiewska K, Kalinowska-Tłuścik J, Shaabani S, Dömling A. Two-Step Macrocycle Synthesis by Classical Ugi Reaction. The Journal of Organic Chemistry. 83: 1441-1447. PMID 29327924 DOI: 10.1021/acs.joc.7b02984  0.501
2017 Chandgude AL, Dömling A. Direct Amination of α-Hydroxy Amides. Asian Journal of Organic Chemistry. 6: 981-983. PMID 32864291 DOI: 10.1002/ajoc.201700277  0.401
2017 Chandgude AL, Li J, Dömling A. 2-Nitrobenzyl Isocyanide as a Universal Convertible Isocyanide. Asian Journal of Organic Chemistry. 6: 798-801. PMID 31236321 DOI: 10.1002/ajoc.201700177  0.416
2017 Chandgude AL, Narducci D, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. Diastereoselective One Pot Five-Component Reaction toward 4-(Tetrazole)-1,3-Oxazinanes. Rsc Advances. 7: 49995-49998. PMID 29430295 DOI: 10.1039/C7RA07392E  0.437
2017 Patil P, Mishra B, Sheombarsing G, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. Library-to-library synthesis of highly substituted α-aminomethyl tetrazoles via Ugi reaction. Acs Combinatorial Science. PMID 29215263 DOI: 10.1021/acscombsci.7b00137  0.426
2017 Abdelraheem EMM, Madhavachary R, Rossetti A, Kurpiewska K, Kalinowska-Tłuścik J, Shaabani S, Dömling A. Ugi Multicomponent Reaction Based Synthesis of Medium-Sized Rings. Organic Letters. 19: 6176-6179. PMID 29083197 DOI: 10.1021/acs.orglett.7b03094  0.671
2017 Abdelraheem EMM, de Haan MP, Patil P, Kurpiewska K, Kalinowska-Tłuścik J, Shaabani S, Dömling A. Concise Synthesis of Tetrazole Macrocycle. Organic Letters. 19: 5078-5081. PMID 28901777 DOI: 10.1021/acs.orglett.7b02319  0.442
2017 Vishwanatha TM, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. Cysteine Isocyanide in Multicomponent Reaction: Synthesis of Peptido-Mimetic 1,3-Azoles. The Journal of Organic Chemistry. 82: 9585-9594. PMID 28817272 DOI: 10.1021/acs.joc.7b01615  0.499
2017 Madhavachary R, Wang Q, Dömling A. With unprotected amino acids to tetrazolo peptidomimetics. Chemical Communications (Cambridge, England). PMID 28707691 DOI: 10.1039/c7cc03370b  0.683
2017 Vishwanatha TM, Bergamaschi E, Dömling A. Sulfur-Switch Ugi Reaction for Macrocyclic Disulfide-Bridged Peptidomimetics. Organic Letters. 19: 3195-3198. PMID 28581763 DOI: 10.1021/acs.orglett.7b01324  0.438
2017 Patil P, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. Ammonia-Promoted One-Pot Tetrazolopiperidinone Synthesis by Ugi Reaction. Acs Combinatorial Science. 19: 343-350. PMID 28240545 DOI: 10.1021/acscombsci.7b00033  0.472
2017 Chandgude AL, Dömling A. N-Hydroxyimide Ugi Reaction toward α-Hydrazino Amides. Organic Letters. 19: 1228-1231. PMID 28220702 DOI: 10.1021/acs.orglett.7b00205  0.382
2017 Wang Y, Patil P, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. Two cycles with one catch: hydrazine in Ugi 4-CR and its post-cyclizations. Acs Combinatorial Science. PMID 28181791 DOI: 10.1021/acscombsci.7b00009  0.487
2017 Patil P, Madhavachary R, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. De Novo Assembly of Highly Substituted Morpholines and Piperazines. Organic Letters. 19: 642-645. PMID 28102692 DOI: 10.1021/acs.orglett.6b03807  0.675
2016 Chandgude AL, Dömling A. Unconventional Passerini Reaction toward α-Aminoxy-amides. Organic Letters. 18: 6396-6399. PMID 27978705 DOI: 10.1021/acs.orglett.6b03293  0.421
2016 Chandgude AL, Dömling A. An Efficient Passerini Tetrazole Reaction (PT-3CR). Green Chemistry : An International Journal and Green Chemistry Resource : Gc. 18: 3718-3721. PMID 27840590 DOI: 10.1039/C6GC00910G  0.362
2016 Kroon E, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. Cleavable β-Cyanoethyl Isocyanide in the Ugi Tetrazole Reaction. Organic Letters. 18: 4762-4765. PMID 27610711 DOI: 10.1021/acs.orglett.6b01826  0.42
2016 Abdelraheem EM, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. Artificial Macrocycles by Ugi Reaction and Passerini Ring Closure. The Journal of Organic Chemistry. 81: 8789-8795. PMID 27598302 DOI: 10.1021/acs.joc.6b01430  0.479
2016 Boltjes A, Shrinidhi A, van de Kolk K, Herdtweck E, Dömling A. Gd-TEMDO: Design, Synthesis, and MRI Application. Chemistry (Weinheim An Der Bergstrasse, Germany). 22: 7352-6. PMID 26991633 DOI: 10.1002/chem.201600720  0.347
2016 Patil P, de Haan M, Kurpiewska K, Kalinowska-Tłuścik J, Dömling A. Versatile Protecting-Group Free Tetrazolomethane Amine Synthesis by Ugi Reaction. Acs Combinatorial Science. 18: 170-5. PMID 26848739 DOI: 10.1021/acscombsci.5b00189  0.444
2016 Zhao T, Kurpiewska K, Kalinowska-Tłuścik J, Herdtweck E, Dömling A. α-Amino Acid-Isosteric α-Amino Tetrazoles. Chemistry (Weinheim An Der Bergstrasse, Germany). 22: 3009-18. PMID 26817531 DOI: 10.1002/chem.201504520  0.3
2015 Zarganes-Tzitzikas T, Chandgude AL, Dömling A. Multicomponent Reactions, Union of MCRs and Beyond. Chemical Record (New York, N.Y.). 15: 981-96. PMID 26455350 DOI: 10.1002/tcr.201500201  0.318
2015 Liao GP, Abdelraheem EM, Neochoritis CG, Kurpiewska K, Kalinowska-Tłuścik J, McGowan DC, Dömling A. Versatile Multicomponent Reaction Macrocycle Synthesis Using α-Isocyano-ω-carboxylic Acids. Organic Letters. 17: 4980-3. PMID 26439710 DOI: 10.1021/acs.orglett.5b02419  0.41
2015 Neochoritis CG, Zarganes-Tzitzikas T, Stotani S, Dömling A, Herdtweck E, Khoury K, Dömling A. Leuckart-Wallach Route Toward Isocyanides and Some Applications. Acs Combinatorial Science. 17: 493-9. PMID 26226194 DOI: 10.1021/acscombsci.5b00066  0.422
2015 Neochoritis CG, Stotani S, Mishra B, Dömling A. Efficient isocyanide-less isocyanide-based multicomponent reactions. Organic Letters. 17: 2002-5. PMID 25824100 DOI: 10.1021/acs.orglett.5b00759  0.32
2014 Zarganes-Tzitzikas T, Patil P, Khoury K, Herdtweck E, Dömling A. Concise Synthesis of Tetrazole-keto-piperazines by Two Consecutive Ugi Reactions. European Journal of Organic Chemistry. 2015: 51-55. PMID 26949370 DOI: 10.1002/ejoc.201403401  0.47
2014 Patil P, Khoury K, Herdtweck E, Dömling A. MCR synthesis of a tetracyclic tetrazole scaffold. Bioorganic & Medicinal Chemistry. 23: 2699-715. PMID 25630499 DOI: 10.1016/j.bmc.2014.12.021  0.397
2014 Patil P, Khoury K, Herdtweck E, Dömling A. A universal isocyanide for diverse heterocycle syntheses. Organic Letters. 16: 5736-9. PMID 25351886 DOI: 10.1021/ol5024882  0.474
2014 Boltjes A, Liao GP, Zhao T, Herdtweck E, Dömling A. Ugi 4-CR Synthesis of γ- and δ-Lactams providing new access to diverse enzyme interactions, a PDB analysis. Medchemcomm. 5: 949-952. PMID 25013719 DOI: 10.1039/C4Md00162A  0.302
2014 Boltjes A, Huang Y, van de Velde R, Rijkee L, Wolf S, Gaugler J, Lesniak K, Guzik K, Holak TA, Dömling A. Fragment-based library generation for the discovery of a peptidomimetic p53-Mdm4 inhibitor. Acs Combinatorial Science. 16: 393-6. PMID 24983416 DOI: 10.1021/Co500026B  0.34
2014 Neochoritis CG, Dömling A. Towards a facile and convenient synthesis of highly functionalized indole derivatives based on multi-component reactions. Organic & Biomolecular Chemistry. 12: 1649-51. PMID 24477767 DOI: 10.1039/c4ob00166d  0.451
2013 Sinha MK, Khoury K, Herdtweck E, Dömling A. Various cyclization scaffolds by a truly Ugi 4-CR. Organic & Biomolecular Chemistry. 11: 4792-6. PMID 23760036 DOI: 10.1039/c3ob40523k  0.422
2013 Sinha MK, Khoury K, Herdtweck E, Dömling A. Tricycles by a new Ugi variation and Pictet-Spengler reaction in one pot. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 8048-52. PMID 23649922 DOI: 10.1002/chem.201300962  0.373
2013 Zhao T, Boltjes A, Herdtweck E, Dömling A. Tritylamine as an ammonia surrogate in the Ugi tetrazole synthesis. Organic Letters. 15: 639-41. PMID 23331054 DOI: 10.1021/ol303348m  0.413
2012 Huang Y, Khoury K, Chanas T, Dömling A. Multicomponent synthesis of diverse 1,4-benzodiazepine scaffolds. Organic Letters. 14: 5916-9. PMID 23157402 DOI: 10.1021/Ol302837H  0.314
2012 Khoury K, Sinha MK, Nagashima T, Herdtweck E, Dömling A. Efficient assembly of iminodicarboxamides by a "truly" four-component reaction. Angewandte Chemie (International Ed. in English). 51: 10280-3. PMID 22968839 DOI: 10.1002/anie.201205366  0.333
2012 Wang W, Cao H, Wolf S, Camacho-Horvitz MS, Holak TA, Dömling A. Benzimidazole-2-one: a novel anchoring principle for antagonizing p53-Mdm2. Bioorganic & Medicinal Chemistry. 21: 3982-95. PMID 22789708 DOI: 10.1016/j.bmc.2012.06.020  0.302
2012 Wang K, Herdtweck E, Dömling A. Cyanoacetamides (IV): versatile one-pot route to 2-quinoline-3-carboxamides. Acs Combinatorial Science. 14: 316-22. PMID 22486416 DOI: 10.1021/co3000133  0.481
2012 Dömling A, Wang W, Wang K. Chemistry and biology of multicomponent reactions. Chemical Reviews. 112: 3083-135. PMID 22435608 DOI: 10.1021/cr100233r  0.374
2012 Liu H, William S, Herdtweck E, Botros S, Dömling A. MCR synthesis of praziquantel derivatives. Chemical Biology & Drug Design. 79: 470-7. PMID 22151001 DOI: 10.1111/j.1747-0285.2011.01288.x  0.402
2011 Huang Y, Dömling A. The Gewald multicomponent reaction. Molecular Diversity. 15: 3-33. PMID 20191319 DOI: 10.1007/S11030-010-9229-6  0.418
2010 Wang K, Herdtweck E, Dömling A. One-pot synthesis of 2-amino-indole-3-carboxamide and analogous. Acs Combinatorial Science. 13: 140-6. PMID 21395342 DOI: 10.1021/co100040z  0.395
2010 Wang W, Ollio S, Herdtweck E, Dömling A. Polycyclic compounds by Ugi-Pictet-Spengler sequence. The Journal of Organic Chemistry. 76: 637-44. PMID 21190371 DOI: 10.1021/jo102058s  0.458
2010 Cao H, Liu H, Dömling A. Efficient multicomponent reaction synthesis of the schistosomiasis drug praziquantel. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 12296-8. PMID 20845417 DOI: 10.1002/chem.201002046  0.369
2010 Wang K, Dömling A. Design of a versatile multicomponent reaction leading to 2-amino-5-ketoaryl pyrroles. Chemical Biology & Drug Design. 75: 277-83. PMID 20659110 DOI: 10.1111/j.1747-0285.2009.00942.x  0.497
2010 Huang Y, Dömling A. 1,4-Thienodiazepine-2,5-diones via MCR (II): scaffold hopping by Gewald and Ugi-deprotection-cyclization strategy. Chemical Biology & Drug Design. 76: 130-41. PMID 20545946 DOI: 10.1111/J.1747-0285.2010.00990.X  0.344
2010 Beck B, Srivastava S, Khoury K, Herdtweck E, Dömling A. One-pot multicomponent synthesis of two novel thiolactone scaffolds. Molecular Diversity. 14: 479-91. PMID 20407923 DOI: 10.1007/s11030-010-9249-2  0.445
2010 Wang K, Kim D, Dömling A. Cyanoacetamide MCR (III): three-component Gewald reactions revisited. Journal of Combinatorial Chemistry. 12: 111-8. PMID 19958011 DOI: 10.1021/cc9001586  0.48
2009 Wang W, Herdtweck E, Dömling A. Polycyclic indole alkaloid-type compounds by MCR. Chemical Communications (Cambridge, England). 46: 770-2. PMID 20087515 DOI: 10.1039/b917660h  0.368
2009 Liu H, Dömling A. One-pot synthesis of highly functionalized seleno amino acid derivatives. Chemical Biology & Drug Design. 74: 302-8. PMID 19703033 DOI: 10.1111/j.1747-0285.2009.00854.x  0.439
2009 Wang K, Nguyen K, Huang Y, Dömling A. Cyanoacetamide multicomponent reaction (I): Parallel synthesis of cyanoacetamides. Journal of Combinatorial Chemistry. 11: 920-7. PMID 19694451 DOI: 10.1021/Cc9000778  0.458
2009 Liu H, Dömling A. Efficient and diverse synthesis of indole derivatives. The Journal of Organic Chemistry. 74: 6895-8. PMID 19663394 DOI: 10.1021/jo900986z  0.447
2009 Wang W, Dömling A. Efficient synthesis of arrays of amino acid derived Ugi products with subsequent amidation. Journal of Combinatorial Chemistry. 11: 403-9. PMID 19425617 DOI: 10.1021/cc9000136  0.423
2008 Dömling A, Antuch W, Beck B, Schauer-Vukasinović V. Isosteric exchange of the acylsulfonamide moiety in Abbott's Bcl-XL protein interaction antagonist. Bioorganic & Medicinal Chemistry Letters. 18: 4115-7. PMID 18583128 DOI: 10.1016/j.bmcl.2008.05.096  0.389
2007 Dömling A, Achatz S, Beck B. Novel anti-tuberculosis agents from MCR libraries. Bioorganic & Medicinal Chemistry Letters. 17: 5483-6. PMID 17720495 DOI: 10.1016/j.bmcl.2007.04.066  0.349
2006 Dömling A, Beck B, Fuchs T, Yazbak A. Parallel synthesis of arrays of amino-acid-derived isocyanoamides useful as starting materials in IMCR. Journal of Combinatorial Chemistry. 8: 872-80. PMID 17096576 DOI: 10.1021/cc060068w  0.401
2006 Achatz S, Dömling A. Desosamine in multicomponent reactions. Bioorganic & Medicinal Chemistry Letters. 16: 6360-2. PMID 17070045 DOI: 10.1016/j.bmcl.2006.07.017  0.401
2006 Dömling A. Recent developments in isocyanide based multicomponent reactions in applied chemistry. Chemical Reviews. 106: 17-89. PMID 16402771 DOI: 10.1021/cr0505728  0.351
2004 Kolb J, Beck B, Almstetter M, Heck S, Herdtweck E, Dömling A. New MCRs: the first 4-component reaction leading to 2,4-disubstituted thiazoles. Molecular Diversity. 6: 297-313. PMID 15068094 DOI: 10.1023/b:modi.0000006827.35029.e4  0.409
2004 Beck B, Picard A, Herdtweck E, Dömling A. Highly substituted pyrrolidinones and pyridones by 4-CR/2-CR sequence. Organic Letters. 6: 39-42. PMID 14703345 DOI: 10.1021/ol035787n  0.458
2004 Kusebauch U, Beck B, Messer K, Herdtweck E, Dömling A. Massive parallel catalyst screening: toward asymmetric MCRs. Organic Letters. 5: 4021-4. PMID 14572239 DOI: 10.1021/ol035010u  0.374
2003 Beck B, Larbig G, Mejat B, Magnin-Lachaux M, Picard A, Herdtweck E, Dömling A. Short and diverse route toward complex natural product-like macrocycles. Organic Letters. 5: 1047-50. PMID 12659570 DOI: 10.1021/ol034077e  0.482
2002 Dömling A. Recent advances in isocyanide-based multicomponent chemistry. Current Opinion in Chemical Biology. 6: 306-13. PMID 12023110 DOI: 10.1016/s1367-5931(02)00328-9  0.426
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