Richard N. Loeppky - Publications

University of Missouri - Columbia, Columbia, MO, United States 
Organic Chemistry

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Qu C, Tang E, Loeppky R, Deng Z, Pulley SR, Hong X. Studies towards the synthesis of medermycin via Dötz benzannulation. Chirality. 27: 18-22. PMID 25322945 DOI: 10.1002/Chir.22383  0.375
2010 Cui W, Loeppky RN. ChemInform Abstract: The Synthesis of N-Arylcyclopropylamines via Palladium-Catalyzed C-N Bond Formation. Cheminform. 32: no-no. DOI: 10.1002/CHIN.200130063  0.76
2010 LOEPPKY RN, CUI W. ChemInform Abstract: The Nitrosation of Imidazolines and Oxazolines. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199829067  0.687
2010 LOEPPKY RN, YU L. ChemInform Abstract: Nitrosamines, N-Nitrosoamides, and Diazonium Ions from Tri-N- Substituted Amidines. Cheminform. 22: no-no. DOI: 10.1002/CHIN.199128090  0.43
2008 Baum M, Loeppky RN, Thielen S, Eisenbrand G. Genotoxicity of glycidamide in comparison to 3-N-nitroso-oxazolidin-2-one. Journal of Agricultural and Food Chemistry. 56: 5989-93. PMID 18624445 DOI: 10.1021/Jf703741A  0.354
2008 Loeppky RN, Shi J, Barnes CL, Geddam S. A diazonium ion cascade from the nitrosation of tolazoline, an imidazoline-containing drug Chemical Research in Toxicology. 21: 295-307. PMID 18247523 DOI: 10.1021/tx700317g  0.599
2008 Loeppky RN, Shi J. Nucleoside and DNA adducts from N-nitrosotolazoline. Chemical Research in Toxicology. 21: 319-29. PMID 18232662 DOI: 10.1021/tx700323k  0.609
2008 Loeppky RN, Shi J. N-nitrosotolazoline: decomposition studies of a typical N-nitrosoimidazoline. Chemical Research in Toxicology. 21: 308-18. PMID 18232661 DOI: 10.1021/tx700318k  0.644
2006 Thielen S, Baum M, Hoffmann M, Loeppky RN, Eisenbrand G. Genotoxicity of glycidamide in comparison to (+/-)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide and alpha-acetoxy-N-nitroso-diethanolamine in human blood and in mammalian V79-cells. Molecular Nutrition & Food Research. 50: 430-6. PMID 16598810 DOI: 10.1002/Mnfr.200500227  0.349
2005 Loeppky RN, Sukhtankar S, Gu F, Park M. The carcinogenic significance of reactive intermediates derived from 3-acetoxy- and 5-acetoxy-2-hydroxy-N-nitrosomorpholine. Chemical Research in Toxicology. 18: 1955-66. PMID 16359186 DOI: 10.1021/Tx0502037  0.521
2005 Wu H, Loeppky RN, Glaser R. Nitrosation chemistry of pyrroline, 2-imidazoline, and 2-oxazoline: theoretical Curtin-Hammett analysis of retro-ene and solvent-assisted C-X cleavage reactions of alpha-hydroxy-N-nitrosamines. The Journal of Organic Chemistry. 70: 6790-801. PMID 16095298 DOI: 10.1021/Jo050856S  0.355
2005 Dennehy MK, Loeppky RN. Mass spectrometric methodology for the determination of glyoxaldeoxyguanosine and O6-hydroxyethyldeoxyguanosine DNA adducts produced by nitrosamine bident carcinogens. Chemical Research in Toxicology. 18: 556-65. PMID 15777095 DOI: 10.1021/Tx049802O  0.698
2005 Teuten EL, Loeppky RN. The mechanistic origin of regiochemical changes in the nitrosative N-dealkylation of N,N-dialkyl aromatic amines. Organic & Biomolecular Chemistry. 3: 1097-108. PMID 15750654 DOI: 10.1039/B418457B  0.754
2004 Loeppky RN, Yu H. Amidine nitrosation. The Journal of Organic Chemistry. 69: 3015-24. PMID 15104439 DOI: 10.1021/jo035884u  0.349
2002 Loeppky RN, Ye Q, Goelzer P, Chen Y. DNA adducts from N-nitrosodiethanolamine and related beta-oxidized nitrosamines in vivo: (32)P-postlabeling methods for glyoxal- and O(6)-hydroxyethyldeoxyguanosine adducts. Chemical Research in Toxicology. 15: 470-82. PMID 11952332 DOI: 10.1021/Tx0101393  0.458
2002 Loeppky RN, Goelzer P. Microsome-mediated oxidation of N-nitrosodiethanolamine (NDELA), a bident carcinogen. Chemical Research in Toxicology. 15: 457-69. PMID 11952331 DOI: 10.1021/Tx000267B  0.352
2001 Cui W, Loeppky RN. The synthesis of N -arylcyclopropylamines via palladium-catalyzed C–N bond formation Tetrahedron. 57: 2953-2956. DOI: 10.1016/S0040-4020(01)00118-1  0.75
2000 Loeppky RN, Elomari S. N-Alkyl-N-cyclopropylanilines as mechanistic probes in the nitrosation of N,N-dialkyl aromatic amines. The Journal of Organic Chemistry. 65: 96-103. PMID 10813901 DOI: 10.1021/Jo991104Z  0.586
2000 Park M, Loeppky RN. In vitro DNA deamination by alpha-nitrosaminoaldehydes determined by GC/MS-SIM quantitation. Chemical Research in Toxicology. 13: 72-81. PMID 10688530 DOI: 10.1021/Tx990126D  0.44
1999 Loeppky RN, Cui W, Goelzer P, Park M, Ye Q. Glyoxal-guanine DNA adducts: detection, stability and formation in vivo from nitrosamines. Iarc Scientific Publications. 155-68. PMID 10626217  0.75
1999 Loeppky RN. The mechanism of bioactivation of N-nitrosodiethanolamine. Drug Metabolism Reviews. 31: 175-93. PMID 10065371 DOI: 10.1081/Dmr-100101913  0.464
1999 Loeppky RN, Fuchs A, Janzowski C, Humberd C, Goelzer P, Schneider H, Eisenbrand G. Probing the mechanism of the carcinogenic activation of N-nitrosodiethanolamine with deuterium isotope effects: in vivo induction of DNA single-strand breaks and related in vitro assays. Chemical Research in Toxicology. 11: 1556-66. PMID 9860501 DOI: 10.1021/Tx9801716  0.36
1998 Loeppky RN, Singh SP, Elomari S, Hastings R, Theiss TE. Evidence for radical cations in linked mechanisms of N,N-Dialkyl aromatic amine nitration and nitrosative dealkylation Journal of the American Chemical Society. 120: 5193-5202. DOI: 10.1021/Ja9732744  0.43
1998 Loeppky RN, Cui W. The nitrosation of imidazolines and oxazolines Tetrahedron Letters. 39: 1845-1848. DOI: 10.1016/S0040-4039(98)00128-2  0.76
1998 Park M, Gu F, Loeppky RN. The synthesis of highly reactive, multi-functional α,β-epoxy- and α-acetoxy-nitrosamines Tetrahedron Letters. 39: 1287-1290. DOI: 10.1016/S0040-4039(97)10868-1  0.442
1995 Bae JY, Mende P, Shevlin G, Spiegelhalder B, Preussmann R, Loeppky RN. The nitrosation of hexetidine and hexedine: characterization of the major nitrosamine from common antimicrobial agents. Chemical Research in Toxicology. 7: 868-76. PMID 7696545 DOI: 10.1021/TX00042A023  0.408
1995 Loeppky RN, Srinivasan A. Thiol oxidation by 1,2,3-oxadiazolinium ions, presumed carcinogens Chemical Research in Toxicology. 8: 817-820. PMID 7492730 DOI: 10.1021/Tx00048A001  0.442
1995 Loeppky RN, Xiong H. Acid-catalyzed rearrangements of N-nitrosodehydromorpholine The Journal of Organic Chemistry. 60: 5526-5531. DOI: 10.1021/Jo00122A036  0.487
1994 Loeppky RN, Bae JY. An aziridinium ion intermediate in the nitrosation of a hexetidine model Chemical Research in Toxicology. 7: 861-867. PMID 7696544 DOI: 10.1021/Tx00042A022  0.461
1994 Loeppky RN, Xiong H. The synthesis of deuterium-labeled N-nitrosodiethanolamine and N-nitroso-2-hydroxymorpholine Journal of Labelled Compounds and Radiopharmaceuticals. 34: 1099-1110. DOI: 10.1002/Jlcr.2580341114  0.479
1991 Wilcox AL, Bao YT, Loeppky RN. Pyrroles as effective agents for blocking amine nitrosation. Chemical Research in Toxicology. 4: 373-81. PMID 1912323 DOI: 10.1021/Tx00021A019  0.395
1991 Loeppky RN, Feng Q, Srinivasan A, Glaser R, Barnes CL, Sharp PR. N-Nitrosoaziridinium Ion Isomerization: Dihydrodiazete N-Oxides and Azoxyalkenes from Aziridine Nitrosation Journal of the American Chemical Society. 113: 2308-2309.  0.386
1990 Loeppky RN, Yu L. Nitrosamines, N-nitrosoamides, and diazonium ions from tri-N-substituted amidines Tetrahedron Letters. 31: 3263-3266. DOI: 10.1016/S0040-4039(00)89039-5  0.542
1988 LOEPPKY RN, FLEISCHMANN ED, ADAMS JE, TOMASIK W, SCHLEMPER EO, WONG TC. ChemInform Abstract: The 5-Hydroxy-1,2,3-oxadiazolinium Ion: Neighboring Group Interaction Between N-Nitroso and Aldehyde Carbonyl. Cheminform. 19. DOI: 10.1002/CHIN.198851204  0.324
1987 Loeppky RN, Tomasik W, Kerrick BE. Nitroso transfer from alpha-nitrosamino aldehydes: implications for carcinogenesis. Carcinogenesis. 8: 941-6. PMID 3594727 DOI: 10.1093/CARCIN/8.7.941  0.324
1984 LOEPPKY RN, OUTRAM JR, TOMASIK W, FAULCONER JM. ChemInform Abstract: Rapid Nitrosamine Formation from a Tertiary Amine: the Nitrosation of 2-(N,N-Dimethylaminomethyl)pyrrole. Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198405126  0.463
1983 Loeppky R, Outram J, Tomasik W, Faulconer J. Rapid nitrosamine formation from a tertiary amine: The nitrosation of 2-(N,N-Dimethylaminomethyl)pyrrole Tetrahedron Letters. 24: 4271-4274. DOI: 10.1016/S0040-4039(00)88318-5  0.547
1977 Leimer KR, Loeppky RN, Gehrke CW. Identification of an interfering compound in the gas—liquid chromatographic determination of N2,N2-dimethylguanosine Journal of Chromatography B: Biomedical Sciences and Applications. 143: 104-108. DOI: 10.1016/S0378-4347(00)81333-X  0.487
1976 Loeppky RN, Smith DH. Nitrosation of 1-substituted aziridines The Journal of Organic Chemistry. 41: 1578-1585. DOI: 10.1021/Jo00871A021  0.339
1975 Agris PF, Fujiwara FG, Schmidt CF, Loeppky RN. Utilization of an Escherichia coli mutant for carbon-13 enrichment of tRNA for NMR studies. Nucleic Acids Research. 2: 1503-12. PMID 1101225 DOI: 10.1093/Nar/2.9.1503  0.305
1967 Leonard NJ, Achmatowicz S, Loeppky RN, Carraway KL, Grimm WA, Szweykowska A, Hamzi QH, Skoog F. Development of cytokinin activity by rearrangement of 1-substituted adenines to 6-substituted aminopurines: inactivation by N6, 1-cyclization. Proceedings of the National Academy of Sciences of the United States of America. 56: 709-16. PMID 5229988 DOI: 10.1073/Pnas.56.2.709  0.308
1967 Loeppky RN, Rotman M. Silver tetrafluoroborate induced rearrangement of N-chloroketimines The Journal of Organic Chemistry. 32: 4010-4017. DOI: 10.1021/Jo01287A063  0.475
1967 Skoog F, Hamzi HQ, Szweykowska AM, Leonard NJ, Carraway KL, Fujii T, Helgeson JP, Loeppky RN. Cytokinins: Structure/activity relationships Phytochemistry. 6: 1169-1192. DOI: 10.1016/S0031-9422(00)86080-X  0.332
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