Brian T. Chait - Publications

Affiliations: 
Rockefeller University, New York, NY, United States 
Area:
Biochemistry, Analytical Chemistry

120 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Olinares PDB, Chait BT. Native Mass Spectrometry Analysis of Affinity-Captured Endogenous Yeast RNA Exosome Complexes. Methods in Molecular Biology (Clifton, N.J.). 2062: 357-382. PMID 31768985 DOI: 10.1007/978-1-4939-9822-7_17  0.44
2019 Presslee S, Slater GJ, Pujos F, Forasiepi AM, Fischer R, Molloy K, Mackie M, Olsen JV, Kramarz A, Taglioretti M, Scaglia F, Lezcano M, Lanata JL, Southon J, Feranec R, ... ... Chait BT, et al. Palaeoproteomics resolves sloth relationships. Nature Ecology & Evolution. PMID 31171860 DOI: 10.1038/s41559-019-0909-z  0.44
2019 Hayama R, Sorci M, Keating Iv JJ, Hecht LM, Plawsky JL, Belfort G, Chait BT, Rout MP. Interactions of nuclear transport factors and surface-conjugated FG nucleoporins: Insights and limitations. Plos One. 14: e0217897. PMID 31170242 DOI: 10.1371/journal.pone.0217897  0.8
2018 Mayle R, Langston L, Molloy KR, Zhang D, Chait BT, O'Donnell ME. Mcm10 has potent strand-annealing activity and limits translocase-mediated fork regression. Proceedings of the National Academy of Sciences of the United States of America. PMID 30598452 DOI: 10.1073/pnas.1819107116  0.64
2018 Delgado-Benito V, Rosen DB, Wang Q, Gazumyan A, Pai JA, Oliveira TY, Sundaravinayagam D, Zhang W, Andreani M, Keller L, Kieffer-Kwon KR, Pękowska A, Jung S, Driesner M, Subbotin RI, ... ... Chait BT, et al. The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination. Molecular Cell. PMID 30293785 DOI: 10.1016/j.molcel.2018.08.042  0.4
2018 Jishage M, Yu X, Shi Y, Ganesan SJ, Chen WY, Sali A, Chait BT, Asturias FJ, Roeder RG. Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1. Nature Structural & Molecular Biology. 25: 859-867. PMID 30190596 DOI: 10.1038/s41594-018-0118-5  0.52
2018 Schrank BR, Aparicio T, Li Y, Chang W, Chait BT, Gundersen GG, Gottesman ME, Gautier J. Nuclear ARP2/3 drives DNA break clustering for homology-directed repair. Nature. PMID 29925947 DOI: 10.1038/s41586-018-0237-5  0.68
2018 Kim SJ, Fernandez-Martinez J, Nudelman I, Shi Y, Zhang W, Raveh B, Herricks T, Slaughter BD, Hogan JA, Upla P, Chemmama IE, Pellarin R, Echeverria I, Shivaraju M, Chaudhury AS, ... ... Chait BT, et al. Integrative structure and functional anatomy of a nuclear pore complex. Nature. 555: 475-482. PMID 29539637 DOI: 10.1038/nature26003  0.8
2018 Sanghai ZA, Miller L, Molloy KR, Barandun J, Hunziker M, Chaker-Margot M, Wang J, Chait BT, Klinge S. Modular assembly of the nucleolar pre-60S ribosomal subunit. Nature. PMID 29512650 DOI: 10.1038/nature26156  0.64
2018 Holden JM, Koreny L, Obado S, Ratushny AV, Chen WM, Bart JM, Navarro M, Chait BT, Aitchison JD, Rout MP, Field MC. Involvement in surface antigen expression by a moonlighting FG-repeat nucleoporin in trypanosomes. Molecular Biology of the Cell. PMID 29496964 DOI: 10.1091/mbc.E17-06-0430  0.8
2018 Taylor MS, Altukhov I, Molloy KR, Mita P, Jiang H, Adney EM, Wudzinska A, Badri S, Ischenko D, Eng G, Burns KH, Fenyö D, Chait BT, Alexeev D, Rout MP, et al. Dissection of affinity captured LINE-1 macromolecular complexes. Elife. 7. PMID 29309035 DOI: 10.7554/eLife.30094  0.8
2017 Kleiner RE, Hang LE, Molloy KR, Chait BT, Kapoor TM. A Chemical Proteomics Approach to Reveal Direct Protein-Protein Interactions in Living Cells. Cell Chemical Biology. PMID 29104064 DOI: 10.1016/j.chembiol.2017.10.001  0.64
2017 Barandun J, Chaker-Margot M, Hunziker M, Molloy KR, Chait BT, Klinge S. The complete structure of the small-subunit processome. Nature Structural & Molecular Biology. PMID 28945246 DOI: 10.1038/nsmb.3472  0.64
2017 Kang JY, Olinares PD, Chen J, Campbell EA, Mustaev A, Chait BT, Gottesman ME, Darst SA. Structural basis of transcription arrest by coliphage HK022 nun in an Escherichia coli RNA polymerase elongation complex. Elife. 6. PMID 28318486 DOI: 10.7554/eLife.25478  0.4
2017 Manna PT, Obado SO, Boehm C, Gadelha C, Sali A, Chait BT, Rout MP, Field MC. Lineage-specific proteins essential for endocytosis in trypanosomes. Journal of Cell Science. PMID 28232524 DOI: 10.1242/jcs.191478  0.8
2017 Boehm CM, Obado S, Gadelha C, Kaupisch A, Manna PT, Gould GW, Munson M, Chait BT, Rout MP, Field MC. The Trypanosome Exocyst: A Conserved Structure Revealing a New Role in Endocytosis. Plos Pathogens. 13: e1006063. PMID 28114397 DOI: 10.1371/journal.ppat.1006063  0.8
2017 Wang B, Zhao A, Xie Q, Olinares PD, Chait BT, Novick RP, Muir TW. Functional Plasticity of the AgrC Receptor Histidine Kinase Required for Staphylococcal Virulence. Cell Chemical Biology. 24: 76-86. PMID 28065658 DOI: 10.1016/j.chembiol.2016.12.008  0.32
2016 Orlova N, Gerding M, Ivashkiv O, Olinares PD, Chait BT, Waldor MK, Jeruzalmi D. The replication initiator of the cholera pathogen's second chromosome shows structural similarity to plasmid initiators. Nucleic Acids Research. PMID 28031373 DOI: 10.1093/nar/gkw1288  0.32
2016 Manning LR, Popowicz AM, Padovan JC, Chait BT, Manning JM. Gel filtration of dilute human embryonic hemoglobins reveals basis for their increased oxygen binding. Analytical Biochemistry. PMID 27965062 DOI: 10.1016/j.ab.2016.12.008  0.44
2016 Fernandez-Martinez J, Kim SJ, Shi Y, Upla P, Pellarin R, Gagnon M, Chemmama IE, Wang J, Nudelman I, Zhang W, Williams R, Rice WJ, Stokes DL, Zenklusen D, Chait BT, et al. Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform. Cell. PMID 27839866 DOI: 10.1016/j.cell.2016.10.028  0.8
2016 Maishman L, Obado SO, Alsford S, Bart JM, Chen WM, Ratushny AV, Navarro M, Horn D, Aitchison JD, Chait BT, Rout MP, Field MC. Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression. Nucleic Acids Research. PMID 27625397 DOI: 10.1093/nar/gkw751  0.8
2016 Luo Y, Jacobs EY, Greco TM, Mohammed KD, Tong T, Keegan S, Binley JM, Cristea IM, Fenyö D, Rout MP, Chait BT, Muesing MA. HIV-host interactome revealed directly from infected cells. Nature Microbiology. 1. PMID 27375898 DOI: 10.1038/nmicrobiol.2016.68  0.8
2016 Hunziker M, Barandun J, Petfalski E, Tan D, Delan-Forino C, Molloy KR, Kim KH, Dunn-Davies H, Shi Y, Chaker-Margot M, Chait BT, Walz T, Tollervey D, Klinge S. UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly. Nature Communications. 7: 12090. PMID 27354316 DOI: 10.1038/ncomms12090  0.8
2016 Obado SO, Field MC, Chait BT, Rout MP. High-Efficiency Isolation of Nuclear Envelope Protein Complexes from Trypanosomes. Methods in Molecular Biology (Clifton, N.J.). 1411: 67-80. PMID 27147034 DOI: 10.1007/978-1-4939-3530-7_3  0.8
2016 Chait BT, Cadene M, Olinares PD, Rout MP, Shi Y. Revealing Higher Order Protein Structure Using Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 27080007 DOI: 10.1007/s13361-016-1385-1  0.8
2016 Rivera-Torres IO, Jin TB, Cadene M, Chait BT, Poget SF. Discovery and characterisation of a novel toxin from Dendroaspis angusticeps, named Tx7335, that activates the potassium channel KcsA. Scientific Reports. 6: 23904. PMID 27044983 DOI: 10.1038/srep23904  0.8
2016 Obado SO, Brillantes M, Uryu K, Zhang W, Ketaren NE, Chait BT, Field MC, Rout MP. Interactome Mapping Reveals the Evolutionary History of the Nuclear Pore Complex. Plos Biology. 14: e1002365. PMID 26891179 DOI: 10.1371/journal.pbio.1002365  0.8
2016 Lussignol M, Kopp M, Molloy K, Vizcay-Barrena G, Fleck RA, Dorner M, Bell KL, Chait BT, Rice CM, Catanese MT. Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. 113: 2484-9. PMID 26884193 DOI: 10.1073/pnas.1518934113  0.44
2016 Kellner N, Schwarz J, Sturm M, Fernandez-Martinez J, Griesel S, Zhang W, Chait BT, Rout MP, Kück U, Hurt E. Developing genetic tools to exploit Chaetomium thermophilum for biochemical analyses of eukaryotic macromolecular assemblies. Scientific Reports. 6: 20937. PMID 26864114 DOI: 10.1038/srep20937  0.8
2016 Olinares PD, Dunn AD, Padovan JC, Fernandez-Martinez J, Rout MP, Chait BT. A robust workflow for native mass spectrometric analysis of affinity-isolated endogenous protein assemblies. Analytical Chemistry. PMID 26849307 DOI: 10.1021/acs.analchem.5b04477  0.8
2016 Thompson MK, Fridy PC, Keegan S, Chait BT, Fenyö D, Rout MP. Optimizing selection of large animals for antibody production by screening immune response to standard vaccines. Journal of Immunological Methods. PMID 26775851 DOI: 10.1016/j.jim.2016.01.006  0.8
2015 Morris DH, Yip CK, Shi Y, Chait BT, Wang QJ. BECLIN 1-VPS34 COMPLEX ARCHITECTURE: UNDERSTANDING THE NUTS AND BOLTS OF THERAPEUTIC TARGETS. Frontiers in Biology. 10: 398-426. PMID 26692106 DOI: 10.1007/s11515-015-1374-y  0.8
2015 Sun J, Shi Y, Georgescu RE, Yuan Z, Chait BT, Li H, O'Donnell ME. The architecture of a eukaryotic replisome. Nature Structural & Molecular Biology. PMID 26524492 DOI: 10.1038/nsmb.3113  0.8
2015 LoPiccolo J, Kim SJ, Shi Y, Wu B, Wu H, Chait BT, Singer RH, Sali A, Brenowitz M, Bresnick AR, Backer JM. Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer. The Journal of Biological Chemistry. PMID 26475863 DOI: 10.1074/jbc.M115.689604  0.8
2015 Shi Y, Pellarin R, Fridy PC, Fernandez-Martinez J, Thompson MK, Li Y, Wang QJ, Sali A, Rout MP, Chait BT. A strategy for dissecting the architectures of native macromolecular assemblies. Nature Methods. PMID 26436480 DOI: 10.1038/nmeth.3617  0.8
2015 Kleiner RE, Verma P, Molloy KR, Chait BT, Kapoor TM. Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage response. Nature Chemical Biology. 11: 807-14. PMID 26344695 DOI: 10.1038/nchembio.1908  0.8
2015 Capitan F, Robu AC, Schiopu C, Ilie C, Chait BT, Przybylski M, Zamfir AD. β-Lactoglobulin detected in human milk forms noncovalent complexes with maltooligosaccharides as revealed by chip-nanoelectrospray high-resolution tandem mass spectrometry. Amino Acids. 47: 2399-407. PMID 26123988 DOI: 10.1007/s00726-015-2030-1  0.8
2015 Hakhverdyan Z, Domanski M, Hough LE, Oroskar AA, Oroskar AR, Keegan S, Dilworth DJ, Molloy KR, Sherman V, Aitchison JD, Fenyö D, Chait BT, Jensen TH, Rout MP, LaCava J. Rapid, optimized interactomic screening. Nature Methods. 12: 553-60. PMID 25938370 DOI: 10.1038/nmeth.3395  0.8
2015 Gadelha C, Zhang W, Chamberlain JW, Chait BT, Wickstead B, Field MC. Architecture of a Host-Parasite Interface: Complex Targeting Mechanisms Revealed Through Proteomics. Molecular & Cellular Proteomics : McP. 14: 1911-26. PMID 25931509 DOI: 10.1074/mcp.M114.047647  0.8
2015 LaCava J, Molloy KR, Taylor MS, Domanski M, Chait BT, Rout MP. Affinity proteomics to study endogenous protein complexes: pointers, pitfalls, preferences and perspectives. Biotechniques. 58: 103-19. PMID 25757543 DOI: 10.2144/000114262  0.8
2015 Krutchinsky AN, Padovan JC, Cohen H, Chait BT. Optimizing electrospray interfaces using slowly diverging conical duct (ConDuct) electrodes. Journal of the American Society For Mass Spectrometry. 26: 659-67. PMID 25667060 DOI: 10.1007/s13361-014-1063-0  0.8
2015 Uematsu K, Heiman M, Zelenina M, Padovan J, Chait BT, Aperia A, Nishi A, Greengard P. Protein kinase A directly phosphorylates metabotropic glutamate receptor 5 to modulate its function. Journal of Neurochemistry. 132: 677-86. PMID 25639954 DOI: 10.1111/jnc.13038  0.8
2015 Krutchinsky AN, Padovan JC, Cohen H, Chait BT. Maximizing ion transmission from atmospheric pressure into the vacuum of mass spectrometers with a novel electrospray interface. Journal of the American Society For Mass Spectrometry. 26: 649-58. PMID 25588722 DOI: 10.1007/s13361-014-1062-1  0.8
2014 Holden JM, Koreny L, Kelly S, Chait BT, Rout MP, Field MC, Obado SO. Touching from a distance. Nucleus (Austin, Tex.). 5: 304-10. PMID 25482119 DOI: 10.4161/nucl.32228  0.8
2014 Cevher MA, Shi Y, Li D, Chait BT, Malik S, Roeder RG. Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit. Nature Structural & Molecular Biology. 21: 1028-34. PMID 25383669 DOI: 10.1038/nsmb.2914  0.8
2014 Fridy PC, Li Y, Keegan S, Thompson MK, Nudelman I, Scheid JF, Oeffinger M, Nussenzweig MC, Fenyö D, Chait BT, Rout MP. A robust pipeline for rapid production of versatile nanobody repertoires. Nature Methods. 11: 1253-60. PMID 25362362 DOI: 10.1038/nmeth.3170  0.8
2014 Shi Y, Fernandez-Martinez J, Tjioe E, Pellarin R, Kim SJ, Williams R, Schneidman-Duhovny D, Sali A, Rout MP, Chait BT. Structural characterization by cross-linking reveals the detailed architecture of a coatomer-related heptameric module from the nuclear pore complex. Molecular & Cellular Proteomics : McP. 13: 2927-43. PMID 25161197 DOI: 10.1074/mcp.M114.041673  0.8
2014 Kim SJ, Fernandez-Martinez J, Sampathkumar P, Martel A, Matsui T, Tsuruta H, Weiss TM, Shi Y, Markina-Inarrairaegui A, Bonanno JB, Sauder JM, Burley SK, Chait BT, Almo SC, Rout MP, et al. Integrative structure-function mapping of the nucleoporin Nup133 suggests a conserved mechanism for membrane anchoring of the nuclear pore complex. Molecular & Cellular Proteomics : McP. 13: 2911-26. PMID 25139911 DOI: 10.1074/mcp.M114.040915  0.8
2014 Zhong Y, Morris DH, Jin L, Patel MS, Karunakaran SK, Fu YJ, Matuszak EA, Weiss HL, Chait BT, Wang QJ. Nrbf2 protein suppresses autophagy by modulating Atg14L protein-containing Beclin 1-Vps34 complex architecture and reducing intracellular phosphatidylinositol-3 phosphate levels. The Journal of Biological Chemistry. 289: 26021-37. PMID 25086043 DOI: 10.1074/jbc.M114.561134  0.8
2014 Algret R, Fernandez-Martinez J, Shi Y, Kim SJ, Pellarin R, Cimermancic P, Cochet E, Sali A, Chait BT, Rout MP, Dokudovskaya S. Molecular architecture and function of the SEA complex, a modulator of the TORC1 pathway. Molecular & Cellular Proteomics : McP. 13: 2855-70. PMID 25073740 DOI: 10.1074/mcp.M114.039388  0.8
2014 Li Y, Cross FR, Chait BT. Method for identifying phosphorylated substrates of specific cyclin/cyclin-dependent kinase complexes. Proceedings of the National Academy of Sciences of the United States of America. 111: 11323-8. PMID 25049391 DOI: 10.1073/pnas.1409666111  0.8
2014 Jovanovic-Talisman T, Chait BT, Rout MP. NPC mimics: probing the mechanism of nucleocytoplasmic transport. Methods in Cell Biology. 122: 379-93. PMID 24857739 DOI: 10.1016/B978-0-12-417160-2.00017-5  0.8
2014 Anand P, Grigoryan A, Bhuiyan MH, Ueberheide B, Russell V, Quinoñez J, Moy P, Chait BT, Poget SF, Holford M. Sample limited characterization of a novel disulfide-rich venom peptide toxin from terebrid marine snail Terebra variegata. Plos One. 9: e94122. PMID 24713808 DOI: 10.1371/journal.pone.0094122  0.8
2014 Holden JM, Koreny L, Obado S, Ratushny AV, Chen WM, Chiang JH, Kelly S, Chait BT, Aitchison JD, Rout MP, Field MC. Nuclear pore complex evolution: a trypanosome Mlp analogue functions in chromosomal segregation but lacks transcriptional barrier activity. Molecular Biology of the Cell. 25: 1421-36. PMID 24600046 DOI: 10.1091/mbc.E13-12-0750  0.8
2013 Taylor MS, Lacava J, Mita P, Molloy KR, Huang CR, Li D, Adney EM, Jiang H, Burns KH, Chait BT, Rout MP, Boeke JD, Dai L. Affinity proteomics reveals human host factors implicated in discrete stages of LINE-1 retrotransposition. Cell. 155: 1034-48. PMID 24267889 DOI: 10.1016/j.cell.2013.10.021  0.8
2013 Niepel M, Molloy KR, Williams R, Farr JC, Meinema AC, Vecchietti N, Cristea IM, Chait BT, Rout MP, Strambio-De-Castillia C. The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome. Molecular Biology of the Cell. 24: 3920-38. PMID 24152732 DOI: 10.1091/mbc.E13-07-0412  0.8
2013 Smith TC, Fridy PC, Li Y, Basil S, Arjun S, Friesen RM, Leszyk J, Chait BT, Rout MP, Luna EJ. Supervillin binding to myosin II and synergism with anillin are required for cytokinesis. Molecular Biology of the Cell. 24: 3603-19. PMID 24088567 DOI: 10.1091/mbc.E12-10-0714  0.8
2013 Baker LA, Ueberheide BM, Dewell S, Chait BT, Zheng D, Allis CD. The yeast Snt2 protein coordinates the transcriptional response to hydrogen peroxide-mediated oxidative stress. Molecular and Cellular Biology. 33: 3735-48. PMID 23878396 DOI: 10.1128/MCB.00025-13  0.8
2013 Oh YS, Gao P, Lee KW, Ceglia I, Seo JS, Zhang X, Ahn JH, Chait BT, Patel DJ, Kim Y, Greengard P. SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action. Cell. 152: 831-43. PMID 23415230 DOI: 10.1016/j.cell.2013.01.014  0.8
2013 Di Virgilio M, Callen E, Yamane A, Zhang W, Jankovic M, Gitlin AD, Feldhahn N, Resch W, Oliveira TY, Chait BT, Nussenzweig A, Casellas R, Robbiani DF, Nussenzweig MC. Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching. Science (New York, N.Y.). 339: 711-5. PMID 23306439 DOI: 10.1126/science.1230624  0.8
2013 Li X, Foley EA, Kawashima SA, Molloy KR, Li Y, Chait BT, Kapoor TM. Examining post-translational modification-mediated protein-protein interactions using a chemical proteomics approach. Protein Science : a Publication of the Protein Society. 22: 287-95. PMID 23281010 DOI: 10.1002/pro.2210  0.8
2013 Peterson SE, Li Y, Wu-Baer F, Chait BT, Baer R, Yan H, Gottesman ME, Gautier J. Activation of DSB processing requires phosphorylation of CtIP by ATR. Molecular Cell. 49: 657-67. PMID 23273981 DOI: 10.1016/j.molcel.2012.11.020  0.8
2012 Bozzacco L, Yu H, Dengjel J, Trumpfheller C, Zebroski HA, Zhang N, Küttner V, Ueberheide BM, Deng H, Chait BT, Steinman RM, Mojsov S, Fenyö D. Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein. Plos One. 7: e41897. PMID 22860026 DOI: 10.1371/journal.pone.0041897  0.8
2012 Heller EA, Zhang W, Selimi F, Earnheart JC, ?limak MA, Santos-Torres J, Ibañez-Tallon I, Aoki C, Chait BT, Heintz N. The biochemical anatomy of cortical inhibitory synapses. Plos One. 7: e39572. PMID 22768092 DOI: 10.1371/journal.pone.0039572  0.8
2012 Bhatia S, Kil YJ, Ueberheide B, Chait BT, Tayo L, Cruz L, Lu B, Yates JR, Bern M. Constrained de novo sequencing of conotoxins. Journal of Proteome Research. 11: 4191-200. PMID 22709442 DOI: 10.1021/pr300312h  0.8
2012 Domanski M, Molloy K, Jiang H, Chait BT, Rout MP, Jensen TH, LaCava J. Improved methodology for the affinity isolation of human protein complexes expressed at near endogenous levels. Biotechniques. 1-6. PMID 22668517 DOI: 10.2144/000113864  0.8
2012 Chakravarty AK, Subbotin R, Chait BT, Shuman S. RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates. Proceedings of the National Academy of Sciences of the United States of America. 109: 6072-7. PMID 22474365 DOI: 10.1073/pnas.1201207109  0.8
2012 Fernandez-Martinez J, Phillips J, Sekedat MD, Diaz-Avalos R, Velazquez-Muriel J, Franke JD, Williams R, Stokes DL, Chait BT, Sali A, Rout MP. Structure-function mapping of a heptameric module in the nuclear pore complex. The Journal of Cell Biology. 196: 419-34. PMID 22331846 DOI: 10.1083/jcb.201109008  0.8
2012 Field MC, Adung'a V, Obado S, Chait BT, Rout MP. Proteomics on the rims: insights into the biology of the nuclear envelope and flagellar pocket of trypanosomes. Parasitology. 139: 1158-67. PMID 22309600 DOI: 10.1017/S0031182011002125  0.8
2012 Jishage M, Malik S, Wagner U, Uberheide B, Ishihama Y, Hu X, Chait BT, Gnatt A, Ren B, Roeder RG. Transcriptional regulation by Pol II(G) involving mediator and competitive interactions of Gdown1 and TFIIF with Pol II. Molecular Cell. 45: 51-63. PMID 22244332 DOI: 10.1016/j.molcel.2011.12.014  0.8
2012 Donlin LT, Andresen C, Just S, Rudensky E, Pappas CT, Kruger M, Jacobs EY, Unger A, Zieseniss A, Dobenecker MW, Voelkel T, Chait BT, Gregorio CC, Rottbauer W, Tarakhovsky A, et al. Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization. Genes & Development. 26: 114-9. PMID 22241783 DOI: 10.1101/gad.177758.111  0.8
2012 Li X, Foley EA, Molloy KR, Li Y, Chait BT, Kapoor TM. Quantitative chemical proteomics approach to identify post-translational modification-mediated protein-protein interactions. Journal of the American Chemical Society. 134: 1982-5. PMID 22239320 DOI: 10.1021/ja210528v  0.8
2012 Manning JM, Popowicz AM, Padovan JC, Chait BT, Manning LR. Intrinsic regulation of hemoglobin expression by variable subunit interface strengths. The Febs Journal. 279: 361-9. PMID 22129306 DOI: 10.1111/j.1742-4658.2011.08437.x  0.8
2011 Wilczek C, Chitta R, Woo E, Shabanowitz J, Chait BT, Hunt DF, Shechter D. Protein arginine methyltransferase Prmt5-Mep50 methylates histones H2A and H4 and the histone chaperone nucleoplasmin in Xenopus laevis eggs. The Journal of Biological Chemistry. 286: 42221-31. PMID 22009756 DOI: 10.1074/jbc.M111.303677  0.8
2011 Peterson SE, Li Y, Chait BT, Gottesman ME, Baer R, Gautier J. Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair. The Journal of Cell Biology. 194: 705-20. PMID 21893598 DOI: 10.1083/jcb.201103103  0.8
2011 Scheid JF, Mouquet H, Ueberheide B, Diskin R, Klein F, Oliveira TY, Pietzsch J, Fenyo D, Abadir A, Velinzon K, Hurley A, Myung S, Boulad F, Poignard P, Burton DR, ... ... Chait BT, et al. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science (New York, N.Y.). 333: 1633-7. PMID 21764753 DOI: 10.1126/science.1207227  0.8
2011 Cristea IM, Chait BT. Conjugation of magnetic beads for immunopurification of protein complexes. Cold Spring Harbor Protocols. 2011: pdb.prot5610. PMID 21536766 DOI: 10.1101/pdb.prot5610  0.8
2011 Cristea IM, Chait BT. Affinity purification of protein complexes. Cold Spring Harbor Protocols. 2011: pdb.prot5611. PMID 21536765 DOI: 10.1101/pdb.prot5611  0.8
2011 Myung S, Cohen H, Fenyo D, Padovan JC, Krutchinsky AN, Chait BT. High-Capacity Ion Trap Coupled to a Time-of-Flight Mass Spectrometer for Comprehensive Linked Scans with no Scanning Losses. International Journal of Mass Spectrometry. 301: 211-219. PMID 21516228 DOI: 10.1016/j.ijms.2010.09.013  0.8
2011 Dokudovskaya S, Waharte F, Schlessinger A, Pieper U, Devos DP, Cristea IM, Williams R, Salamero J, Chait BT, Sali A, Field MC, Rout MP, Dargemont C. A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae. Molecular & Cellular Proteomics : McP. 10: M110.006478. PMID 21454883 DOI: 10.1074/mcp.M110.006478  0.8
2011 Li X, Wang QJ, Pan N, Lee S, Zhao Y, Chait BT, Yue Z. Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease. Plos One. 6: e17153. PMID 21390248 DOI: 10.1371/journal.pone.0017153  0.52
2011 Gazumyan A, Timachova K, Yuen G, Siden E, Di Virgilio M, Woo EM, Chait BT, Reina San-Martin B, Nussenzweig MC, McBride KM. Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation. Molecular and Cellular Biology. 31: 442-9. PMID 21135131 DOI: 10.1128/MCB.00349-10  0.8
2011 Bloom J, Cristea IM, Procko AL, Lubkov V, Chait BT, Snyder M, Cross FR. Global analysis of Cdc14 phosphatase reveals diverse roles in mitotic processes. The Journal of Biological Chemistry. 286: 5434-45. PMID 21127052 DOI: 10.1074/jbc.M110.205054  0.8
2011 Berdygulova Z, Westblade LF, Florens L, Koonin EV, Chait BT, Ramanculov E, Washburn MP, Darst SA, Severinov K, Minakhin L. Temporal regulation of gene expression of the Thermus thermophilus bacteriophage P23-45. Journal of Molecular Biology. 405: 125-42. PMID 21050864 DOI: 10.1016/j.jmb.2010.10.049  0.8
2010 Li Y, Stewart NK, Berger AJ, Vos S, Schoeffler AJ, Berger JM, Chait BT, Oakley MG. Escherichia coli condensin MukB stimulates topoisomerase IV activity by a direct physical interaction. Proceedings of the National Academy of Sciences of the United States of America. 107: 18832-7. PMID 20921377 DOI: 10.1073/pnas.1008678107  0.8
2010 Zhang G, Ueberheide BM, Waldemarson S, Myung S, Molloy K, Eriksson J, Chait BT, Neubert TA, Fenyö D. Protein quantitation using mass spectrometry. Methods in Molecular Biology (Clifton, N.J.). 673: 211-22. PMID 20835801 DOI: 10.1007/978-1-60761-842-3_13  0.8
2010 Terhune SS, Moorman NJ, Cristea IM, Savaryn JP, Cuevas-Bennett C, Rout MP, Chait BT, Shenk T. Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA. Plos Pathogens. 6: e1000965. PMID 20585571 DOI: 10.1371/journal.ppat.1000965  0.8
2010 Manning LR, Popowicz AM, Padovan J, Chait BT, Russell JE, Manning JM. Developmental expression of human hemoglobins mediated by maturation of their subunit interfaces. Protein Science : a Publication of the Protein Society. 19: 1595-9. PMID 20572018 DOI: 10.1002/pro.441  0.8
2010 Zilman A, Di Talia S, Jovanovic-Talisman T, Chait BT, Rout MP, Magnasco MO. Enhancement of transport selectivity through nano-channels by non-specific competition. Plos Computational Biology. 6: e1000804. PMID 20548778 DOI: 10.1371/journal.pcbi.1000804  0.8
2010 Cristea IM, Moorman NJ, Terhune SS, Cuevas CD, O'Keefe ES, Rout MP, Chait BT, Shenk T. Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein. Journal of Virology. 84: 7803-14. PMID 20504932 DOI: 10.1128/JVI.00139-10  0.8
2010 Cristea IM, Rozjabek H, Molloy KR, Karki S, White LL, Rice CM, Rout MP, Chait BT, MacDonald MR. Host factors associated with the Sindbis virus RNA-dependent RNA polymerase: role for G3BP1 and G3BP2 in virus replication. Journal of Virology. 84: 6720-32. PMID 20392851 DOI: 10.1128/JVI.01983-09  0.8
2010 Sekedat MD, Fenyö D, Rogers RS, Tackett AJ, Aitchison JD, Chait BT. GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome. Molecular Systems Biology. 6: 353. PMID 20212525 DOI: 10.1038/msb.2010.8  0.8
2009 Oeffinger M, Zenklusen D, Ferguson A, Wei KE, El Hage A, Tollervey D, Chait BT, Singer RH, Rout MP. Rrp17p is a eukaryotic exonuclease required for 5' end processing of Pre-60S ribosomal RNA. Molecular Cell. 36: 768-81. PMID 20005841 DOI: 10.1016/j.molcel.2009.11.011  0.8
2009 Postow L, Woo EM, Chait BT, Funabiki H. Identification of SMARCAL1 as a component of the DNA damage response. The Journal of Biological Chemistry. 284: 35951-61. PMID 19841479 DOI: 10.1074/jbc.M109.048330  0.8
2009 DeGrasse JA, DuBois KN, Devos D, Siegel TN, Sali A, Field MC, Rout MP, Chait BT. Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor. Molecular & Cellular Proteomics : McP. 8: 2119-30. PMID 19525551 DOI: 10.1074/mcp.M900038-MCP200  0.8
2009 Selimi F, Cristea IM, Heller E, Chait BT, Heintz N. Proteomic studies of a single CNS synapse type: the parallel fiber/purkinje cell synapse. Plos Biology. 7: e83. PMID 19402746 DOI: 10.1371/journal.pbio.1000083  0.8
2009 Ueberheide BM, Fenyö D, Alewood PF, Chait BT. Rapid sensitive analysis of cysteine rich peptide venom components. Proceedings of the National Academy of Sciences of the United States of America. 106: 6910-5. PMID 19380747 DOI: 10.1073/pnas.0900745106  0.8
2009 Zhong Y, Wang QJ, Li X, Yan Y, Backer JM, Chait BT, Heintz N, Yue Z. Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nature Cell Biology. 11: 468-76. PMID 19270693 DOI: 10.1038/ncb1854  0.8
2009 Yue Z, Holstein GR, Chait BT, Wang QJ. Using genetic mouse models to study the biology and pathology of autophagy in the central nervous system. Methods in Enzymology. 453: 159-80. PMID 19216906 DOI: 10.1016/S0076-6879(08)04008-1  0.8
2009 Reed B, Varon J, Chait BT, Kreek MJ. Carbon dioxide-induced anesthesia results in a rapid increase in plasma levels of vasopressin. Endocrinology. 150: 2934-9. PMID 19213839 DOI: 10.1210/en.2008-1408  0.8
2009 Jovanovic-Talisman T, Tetenbaum-Novatt J, McKenney AS, Zilman A, Peters R, Rout MP, Chait BT. Artificial nanopores that mimic the transport selectivity of the nuclear pore complex. Nature. 457: 1023-7. PMID 19098896 DOI: 10.1038/nature07600  0.8
2008 DeGrasse JA, Chait BT, Field MC, Rout MP. High-yield isolation and subcellular proteomic characterization of nuclear and subnuclear structures from trypanosomes. Methods in Molecular Biology (Clifton, N.J.). 463: 77-92. PMID 18951162 DOI: 10.1007/978-1-59745-406-3_6  0.8
2008 McBride KM, Gazumyan A, Woo EM, Schwickert TA, Chait BT, Nussenzweig MC. Regulation of class switch recombination and somatic mutation by AID phosphorylation. The Journal of Experimental Medicine. 205: 2585-94. PMID 18838546 DOI: 10.1084/jem.20081319  0.8
2008 Seibert C, Veldkamp CT, Peterson FC, Chait BT, Volkman BF, Sakmar TP. Sequential tyrosine sulfation of CXCR4 by tyrosylprotein sulfotransferases Biochemistry. 47: 11251-11262. PMID 18834145 DOI: 10.1021/bi800965m  0.8
2008 Postow L, Ghenoiu C, Woo EM, Krutchinsky AN, Chait BT, Funabiki H. Ku80 removal from DNA through double strand break-induced ubiquitylation. The Journal of Cell Biology. 182: 467-79. PMID 18678709 DOI: 10.1083/jcb.200802146  0.8
2008 Moorman NJ, Cristea IM, Terhune SS, Rout MP, Chait BT, Shenk T. Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex. Cell Host & Microbe. 3: 253-62. PMID 18407068 DOI: 10.1016/j.chom.2008.03.002  0.8
2008 Woo EM, Fenyo D, Kwok BH, Funabiki H, Chait BT. Efficient identification of phosphorylation by mass spectrometric phosphopeptide fingerprinting. Analytical Chemistry. 80: 2419-25. PMID 18321079 DOI: 10.1021/ac702059p  0.8
2008 Savalia D, Westblade LF, Goel M, Florens L, Kemp P, Akulenko N, Pavlova O, Padovan JC, Chait BT, Washburn MP, Ackermann HW, Mushegian A, Gabisonia T, Molineux I, Severinov K. Genomic and proteomic analysis of phiEco32, a novel Escherichia coli bacteriophage. Journal of Molecular Biology. 377: 774-89. PMID 18294652 DOI: 10.1016/j.jmb.2007.12.077  0.8
2008 Westblade LF, Minakhin L, Kuznedelov K, Tackett AJ, Chang EJ, Mooney RA, Vvedenskaya I, Wang QJ, Fenyö D, Rout MP, Landick R, Chait BT, Severinov K, Darst SA. Rapid isolation and identification of bacteriophage T4-encoded modifications of Escherichia coli RNA polymerase: a generic method to study bacteriophage/host interactions. Journal of Proteome Research. 7: 1244-50. PMID 18271525 DOI: 10.1021/pr070451j  0.8
2008 Butelman ER, Reed B, Chait BT, Mandau M, Yuferov V, Kreek MJ. Limited effects of beta-endorphin compared to loperamide or fentanyl in a neuroendocrine biomarker assay in non-human primates. Psychoneuroendocrinology. 33: 292-304. PMID 18171605 DOI: 10.1016/j.psyneuen.2007.11.011  0.8
2007 Fenyo D, Wang Q, DeGrasse JA, Padovan JC, Cadene M, Chait BT. MALDI sample preparation: the ultra thin layer method. Journal of Visualized Experiments : Jove. 192. PMID 18978997 DOI: 10.3791/192  0.8
2007 Alber F, Dokudovskaya S, Veenhoff LM, Zhang W, Kipper J, Devos D, Suprapto A, Karni-Schmidt O, Williams R, Chait BT, Sali A, Rout MP. The molecular architecture of the nuclear pore complex. Nature. 450: 695-701. PMID 18046406 DOI: 10.1038/nature06405  0.8
2007 Alber F, Dokudovskaya S, Veenhoff LM, Zhang W, Kipper J, Devos D, Suprapto A, Karni-Schmidt O, Williams R, Chait BT, Rout MP, Sali A. Determining the architectures of macromolecular assemblies. Nature. 450: 683-94. PMID 18046405 DOI: 10.1038/nature06404  0.8
2007 Brandenburg J, Schimanski B, Nogoceke E, Nguyen TN, Padovan JC, Chait BT, Cross GA, Günzl A. Multifunctional class I transcription in Trypanosoma brucei depends on a novel protein complex. The Embo Journal. 26: 4856-66. PMID 17972917 DOI: 10.1038/sj.emboj.7601905  0.8
2007 Oeffinger M, Wei KE, Rogers R, DeGrasse JA, Chait BT, Aitchison JD, Rout MP. Comprehensive analysis of diverse ribonucleoprotein complexes. Nature Methods. 4: 951-6. PMID 17922018 DOI: 10.1038/nmeth1101  0.8
2007 Komatsu M, Wang QJ, Holstein GR, Friedrich VL, Iwata J, Kominami E, Chait BT, Tanaka K, Yue Z. Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 104: 14489-94. PMID 17726112 DOI: 10.1073/pnas.0701311104  0.8
2007 Glavy JS, Krutchinsky AN, Cristea IM, Berke IC, Boehmer T, Blobel G, Chait BT. Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex. Proceedings of the National Academy of Sciences of the United States of America. 104: 3811-6. PMID 17360435 DOI: 10.1073/pnas.0700058104  0.8
2006 Cristea IM, Carroll JW, Rout MP, Rice CM, Chait BT, MacDonald MR. Tracking and elucidating alphavirus-host protein interactions. The Journal of Biological Chemistry. 281: 30269-78. PMID 16895903 DOI: 10.1074/jbc.M603980200  0.8
2006 Wang QJ, Ding Y, Kohtz DS, Kohtz S, Mizushima N, Cristea IM, Rout MP, Chait BT, Zhong Y, Heintz N, Yue Z. Induction of autophagy in axonal dystrophy and degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8057-68. PMID 16885219 DOI: 10.1523/JNEUROSCI.2261-06.2006  0.8
2005 Cristea IM, Williams R, Chait BT, Rout MP. Fluorescent proteins as proteomic probes. Molecular & Cellular Proteomics : McP. 4: 1933-41. PMID 16155292 DOI: 10.1074/mcp.M500227-MCP200  0.8
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