| Year |
Citation |
Score |
| 2020 |
McDaniel NK, Iida M, Nickel KP, Longhurst CA, Fischbach SR, Rodems TS, Kranjac CA, Bo AY, Luo Q, Gallagher MM, Welke NB, Mitchell KR, Schulz AE, Eckers JC, Hu R, ... ... Kimple RJ, et al. AXL mediates cetuximab and radiation resistance through tyrosine 821 and the c-ABL kinase pathway in head and neck cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32439698 DOI: 10.1158/1078-0432.Ccr-19-3142 |
0.333 |
|
| 2020 |
Chua MLK, Ma DJ, Anderson CM, Karam SD, Margalit DN, Kimple RJ. Follow-up and management of head and neck cancer patients during the 2019 novel coronavirus (SARS-CoV-2) disease pandemic. Advances in Radiation Oncology. PMID 32426556 DOI: 10.1016/J.Adro.2020.04.031 |
0.322 |
|
| 2020 |
SenthilKumar G, Fisher MM, Skiba JH, Miller MC, Brennan SR, Kaushik S, Bradley ST, Longhurst CA, Buehler D, Nickel KP, Iyer G, Kimple RJ, Baschnagel AM. FGFR inhibition enhances sensitivity to radiation in non-small cell lung cancer. Molecular Cancer Therapeutics. PMID 32371583 DOI: 10.1158/1535-7163.Mct-19-0931 |
0.351 |
|
| 2020 |
Fisher MM, SenthilKumar G, Hu R, Goldstein S, Ong I, Miller M, Brennan SR, Kaushik S, Abel L, Nickel KP, Iyer G, Harari PM, Kimple RJ, Baschnagel AM. Fibroblast Growth Factor Receptors as Targets for Radiosensitization in Head and Neck Squamous Cell Carcinomas. International Journal of Radiation Oncology, Biology, Physics. PMID 32298810 DOI: 10.1016/J.Ijrobp.2020.03.040 |
0.322 |
|
| 2020 |
Cosper PF, Abel L, Lee YS, Paz C, Kaushik S, Nickel KP, Alexandridis R, Scott JG, Bruce JY, Kimple RJ. Patient Derived Models to Study Head and Neck Cancer Radiation Response. Cancers. 12. PMID 32059418 DOI: 10.3390/Cancers12020419 |
0.343 |
|
| 2020 |
Burr AR, Harari PM, Haasl AM, Wieland AM, Bruce JY, Kimple RJ, Hartig GK, McCulloch TM, Witek ME. Clinical outcomes for larynx patients with cancer treated with refinement of high-dose radiation treatment volumes. Head & Neck. PMID 32057151 DOI: 10.1002/Hed.26098 |
0.327 |
|
| 2020 |
Burr A, Harari P, Griffith A, Haasl A, Kimple R, Glazer T, Hartig G, McCulloch T, Witek M. Clinical Outcomes for Larynx Cancer Patients Treated with Refinement of High-Dose Radiation Treatment Volumes International Journal of Radiation Oncology Biology Physics. 108. DOI: 10.1016/J.Ijrobp.2020.02.567 |
0.317 |
|
| 2020 |
Lee YS, Skiba J, SenthilKumar G, Bradley ST, Nickel KP, Kimple RJ. Inhibition of radiation-induced autophagy improves control of head and neck squamous cell carcinoma International Journal of Radiation Oncology Biology Physics. 106: 1187. DOI: 10.1016/J.Ijrobp.2019.11.124 |
0.309 |
|
| 2019 |
Pasch CA, Favreau PF, Yueh AE, Babiarz CP, Gillette A, Sharick JT, Karim MR, Nickel KP, DeZeeuw AK, Sprackling CM, Emmerich PB, DeStefanis RA, Pitera RT, Payne SN, Korkos DP, ... ... Kimple RJ, et al. Patient-derived cancer organoid cultures to predict sensitivity to chemotherapy and radiation. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31175091 DOI: 10.1158/1078-0432.Ccr-18-3590 |
0.309 |
|
| 2019 |
Burr AR, Harari PM, Ko HC, Bruce JY, Kimple RJ, Witek ME. Reducing radiotherapy target volume expansion for patients with HPV-associated oropharyngeal cancer. Oral Oncology. 92: 52-56. PMID 31010623 DOI: 10.1016/J.Oraloncology.2019.03.013 |
0.324 |
|
| 2019 |
Lee Y, Skiba J, Kubatzke J, Nickel KP, Kimple R. Abstract 4273: Inhibition of autophagy increases HNSCC sensitivity to cancer therapies Cancer Research. 79: 4273-4273. DOI: 10.1158/1538-7445.Am2019-4273 |
0.37 |
|
| 2019 |
SenthilKumar G, Miller M, Fisher M, Brennan S, Kaushik S, Able L, Harari PM, Iyer G, Kimple RJ, Baschnagel AM. Abstract 2929: Radiosensitization of head and neck cancer by FGFR inhibition Cancer Research. 79: 2929-2929. DOI: 10.1158/1538-7445.Am2019-2929 |
0.397 |
|
| 2019 |
Miller M, Fisher M, Senthilkumar G, Kaushik S, Able L, Brennan S, Iyer G, Kimple R, Baschnagel AM. Abstract 2924: Evaluation of the pan-FGFR inhibitor AZD4547 with radiation in non-small cell lung cancer Cancer Research. 79: 2924-2924. DOI: 10.1158/1538-7445.Am2019-2924 |
0.37 |
|
| 2018 |
McDaniel NK, Cummings CT, Iida M, Hulse J, Pearson HE, Vasileiadi E, Parker RE, Orbuch RA, Ondracek OJ, Welke NB, Kang GH, Davies KD, Wang X, Frye SV, Earp HS, ... ... Kimple RJ, et al. MERTK mediates intrinsic and adaptive resistance to AXL-targeting agents. Molecular Cancer Therapeutics. PMID 30093568 DOI: 10.1158/1535-7163.Mct-17-1239 |
0.348 |
|
| 2018 |
Redlich N, Robinson AM, Nickel KP, Stein AP, Wheeler DL, Adkins DR, Uppaluri R, Kimple RJ, Van Tine BA, Michel LS. Anti-Trop2 blockade enhances the therapeutic efficacy of ErbB3 inhibition in head and neck squamous cell carcinoma. Cell Death & Disease. 9: 5. PMID 29305574 DOI: 10.1038/S41419-017-0029-0 |
0.318 |
|
| 2018 |
Fisher MM, Swick AD, Nickel KP, Kimple RJ. Abstract 856: Selection of radiosensitizers based on HRAS mutation in bladder cancer Cancer Research. 78: 856-856. DOI: 10.1158/1538-7445.Am2018-856 |
0.358 |
|
| 2018 |
Funk LC, Lee DL, Kimple RJ, Lambert PF, Weaver BA. Abstract 1846: HPV oncoproteins cause specific types of chromosomal instability in head and neck cancer Cancer Research. 78: 1846-1846. DOI: 10.1158/1538-7445.Am2018-1846 |
0.324 |
|
| 2018 |
McDaniel NK, Cummings CT, Brand TM, Iida M, Hulse J, Pearson HE, Orbuch RA, Ondracek OJ, Davies KD, Gill P, Wang X, Frye SV, Earp HS, Kimple RJ, Harari PM, et al. Abstract A140: MERTK mediates intrinsic and adaptive resistance to AXL-targeting agents Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-A140 |
0.352 |
|
| 2017 |
Kirsch DG, Diehn M, Kesarwala AH, Maity A, Morgan MA, Schwarz JK, Bristow R, Demaria S, Eke I, Griffin RJ, Haas-Kogan D, Higgins GS, Kimmelman AC, Kimple RJ, Lombaert IM, et al. The Future of Radiobiology. Journal of the National Cancer Institute. PMID 29126306 DOI: 10.1093/Jnci/Djx231 |
0.307 |
|
| 2017 |
Pearson HE, Iida M, Orbuch RA, McDaniel NK, Nickel KP, Kimple RJ, Arbiser J, Wheeler DL. Overcoming resistance to cetuximab with honokiol, a small-molecule polyphenol. Molecular Cancer Therapeutics. PMID 29054984 DOI: 10.1158/1535-7163.Mct-17-0384 |
0.337 |
|
| 2017 |
Ko HC, Harari PM, Sacotte RM, Chen S, Wieland AM, Yu M, Baschnagel AM, Bruce JY, Kimple RJ, Witek ME. Prognostic implications of human papillomavirus status for patients with non-oropharyngeal head and neck squamous cell carcinomas. Journal of Cancer Research and Clinical Oncology. PMID 28752235 DOI: 10.1007/S00432-017-2481-8 |
0.306 |
|
| 2017 |
Prabakaran PJ, Javaid AM, Swick AD, Werner LR, Nickel KP, Sampene E, Hu R, Ong IM, Bruce JY, Hartig GK, Wieland A, Canon J, Harari PM, Kimple RJ. Radiosensitization of adenoid cystic carcinoma with MDM2 inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28659312 DOI: 10.1158/1078-0432.Ccr-17-0969 |
0.338 |
|
| 2017 |
Pointer KB, Ko HC, Brower JV, Witek ME, Kimple RJ, Lloyd RV, Harari PM, Baschnagel AM. Small cell carcinoma of the head and neck: An analysis of the National Cancer Database. Oral Oncology. 69: 92-98. PMID 28559027 DOI: 10.1016/J.Oraloncology.2017.04.009 |
0.327 |
|
| 2017 |
Swick AD, Prabakaran PJ, Miller MC, Javaid AM, Fisher MM, Sampene E, Ong IM, Hu R, Iida M, Nickel KP, Bruce JY, Wheeler DL, Kimple RJ. Co-targeting mTORC and EGFR signaling as a therapeutic strategy in HNSCC. Molecular Cancer Therapeutics. PMID 28446642 DOI: 10.1200/Jco.2017.35.15_Suppl.E17509 |
0.339 |
|
| 2017 |
Swick AD, Stein AP, McCulloch TM, Hartig GK, Ong IM, Sampene E, Prabakaran PJ, Liu CZ, Kimple RJ. Defining the boundaries and expanding the utility of head and neck cancer patient derived xenografts. Oral Oncology. 64: 65-72. PMID 28024726 DOI: 10.1016/J.Oraloncology.2016.11.017 |
0.315 |
|
| 2017 |
Swick AD, Prabakaran PJ, Miller MC, Javaid AM, Fisher MM, Sampene E, Ong IM, Iida M, Wheeler DL, Nickel KP, Bruce JY, Kimple RJ. Abstract 51: Potential and challenges in co-targeting mTORC and EGFR signaling as a therapeutic strategy in HNSCC Clinical Cancer Research. 23: 51-51. DOI: 10.1158/1557-3265.Aacrahns17-51 |
0.366 |
|
| 2017 |
Black NK, Iida M, Rodems TS, Brand TM, Kimple RJ, Wheeler DL. Abstract 4176: Targeting TAM family members with antibody or small molecule inhibitors enhances therapeutic modalities of HNSCC Cancer Research. 77: 4176-4176. DOI: 10.1158/1538-7445.Am2017-4176 |
0.334 |
|
| 2017 |
Eckers JC, Swick AD, Fowler T, Skiba J, Nickel KP, Kimple RJ. Abstract 3307: Induction of autophagy as a mechanism of therapeutic resistance in head and neck cancer Cancer Research. 77: 3307-3307. DOI: 10.1158/1538-7445.Am2017-3307 |
0.359 |
|
| 2017 |
Swick AD, Prabakaran PJ, Javaid A, Miller M, Fisher M, Sampene E, Ong IM, Nickel K, Kimple RJ. Abstract 149: Co-targeting mTORC and EGFR signaling as a potential therapeutic strategy in HNSCC Cancer Research. 77: 149-149. DOI: 10.1158/1538-7445.Am2017-149 |
0.366 |
|
| 2016 |
Iida M, Bahrar H, Brand TM, Pearson HE, Coan JP, Orbuch RA, Flanigan BG, Swick AD, Prabakaran P, Lantto J, Horak ID, Kragh M, Salgia R, Kimple RJ, Wheeler DL. Targeting the HER family with Pan-HER effectively overcomes resistance to cetuximab. Molecular Cancer Therapeutics. PMID 27422810 DOI: 10.1016/S0959-8049(16)32810-6 |
0.316 |
|
| 2016 |
Campos D, Peeters W, Nickel K, Burkel B, Bussink J, Kimple RJ, van der Kogel A, Eliceiri KW, Kissick MW. Radiation Promptly Alters Cancer Live Cell Metabolic Fluxes: An In Vitro Demonstration. Radiation Research. 185: 496-504. PMID 27128739 DOI: 10.1667/Rr14093.1 |
0.324 |
|
| 2016 |
Prabakaran PJ, Swick AD, Nickel KP, Yang DT, Werner LR, Bruce JY, Wieland A, McCulloch TM, Hartig GK, Harari PM, Kimple RJ. Patient derived adenoid cystic carcinoma xenografts to examine personalized cancer treatment approaches. Journal of Clinical Oncology. 34. DOI: 10.1200/Jco.2016.34.15_Suppl.E14080 |
0.311 |
|
| 2016 |
Chatterjee A, Nickel K, Kimple RJ. Abstract 3356: Characterization and enrichment of head and neck cancer stem cells suggests differences between HPV+ and HPV- subtypes of HNSCC cells Cancer Research. 76: 3356-3356. DOI: 10.1158/1538-7445.Am2016-3356 |
0.343 |
|
| 2016 |
Prabakaran P, Nickel KP, Yang DT, Werner LR, Bruce JY, Wieland AM, McCulloch TM, Hartig GK, Harari PM, Swick AD, Kimple RJ. Abstract 3044: Patient-derived adenoid cystic carcinoma xenografts to study molecular target modulation of tumor radiosensitivity Cancer Research. 76: 3044-3044. DOI: 10.1158/1538-7445.Am2016-3044 |
0.339 |
|
| 2016 |
Swick AD, Xiaojun T, Fowler T, Nickel K, Anderson RA, Kimple RJ. Abstract 2129: Induction of autophagy as a mechanism of therapeutic resistance in head and neck cancer Cancer Research. 76: 2129-2129. DOI: 10.1158/1538-7445.Am2016-2129 |
0.355 |
|
| 2016 |
Campos D, Peeters W, Nickel K, Burkel B, Bussink J, Kimple R, van der Kogel A, Eliceiri K, Kissick M. SU-G-TeP3-10: Radiation Induces Prompt Live-Cell Metabolic Fluxes Medical Physics. 43: 3676-3676. DOI: 10.1118/1.4957090 |
0.33 |
|
| 2015 |
Romick-Rosendale LE, Hoskins EE, Privette Vinnedge LM, Foglesong GD, Brusadelli MG, Potter SS, Komurov K, Brugmann SA, Lambert P, Kimple RJ, Virts EL, Hanenberg H, Gillison ML, Wells SI. Defects in the Fanconi anemia pathway in head and neck cancer cells stimulate tumor cell invasion through DNA-PK and Rac1 signaling. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26603260 DOI: 10.1158/1078-0432.Ccr-15-2209 |
0.33 |
|
| 2015 |
Fru LC, Adamson EB, Campos DD, Fain SB, Jacques SL, van der Kogel AJ, Nickel KP, Song C, Kimple RJ, Kissick MW. Potential role of the glycolytic oscillator in acute hypoxia in tumors. Physics in Medicine and Biology. 60: 9215-9225. PMID 26576743 DOI: 10.1088/0031-9155/60/24/9215 |
0.309 |
|
| 2015 |
Francis DM, Huang S, Armstrong EA, Werner LR, Hullett CR, Li C, Morris ZS, Swick AD, Kragh M, Lantto J, Kimple RJ, Harari PM. Pan-HER receptor inhibition augments radiation response in human lung and head and neck cancer models. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26420857 DOI: 10.1158/1078-0432.Ccr-15-1664 |
0.316 |
|
| 2015 |
Swick AD, Chatterjee A, De Costa AA, Kimple RJ. Modulation of therapeutic sensitivity by human papillomavirus. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 26364887 DOI: 10.1016/J.Radonc.2015.09.002 |
0.305 |
|
| 2015 |
Morris ZS, Weichert JP, Saker J, Armstrong EA, Besemer A, Bednarz B, Kimple RJ, Harari PM. Therapeutic combination of radiolabeled CLR1404 with external beam radiation in head and neck cancer model systems. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 116: 504-9. PMID 26123834 DOI: 10.1016/J.Radonc.2015.06.015 |
0.318 |
|
| 2015 |
Kimple RJ, Harari PM. The prognostic value of HPV in head and neck cancer patients undergoing postoperative chemoradiotherapy. Annals of Translational Medicine. 3: S14. PMID 26046059 DOI: 10.3978/J.Issn.2305-5839.2015.01.37 |
0.345 |
|
| 2015 |
Kimple RJ, Sher DJ. Human papillomavirus and head and neck cancer. International Journal of Radiation Oncology, Biology, Physics. 92: 196-9. PMID 25968816 DOI: 10.1016/J.Ijrobp.2015.01.015 |
0.309 |
|
| 2015 |
Brand TM, Iida M, Stein AP, Corrigan KL, Braverman CM, Coan JP, Pearson HE, Bahrar H, Fowler TL, Bednarz BP, Saha S, Yang D, Gill PS, Lingen MW, Saloura V, ... ... Kimple RJ, et al. AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2601-12. PMID 25767293 DOI: 10.1158/1078-0432.Ccr-14-2648 |
0.322 |
|
| 2015 |
Stein AP, Swick AD, Smith MA, Blitzer GC, Yang RZ, Saha S, Harari PM, Lambert PF, Liu CZ, Kimple RJ. Xenograft assessment of predictive biomarkers for standard head and neck cancer therapies. Cancer Medicine. 4: 699-712. PMID 25619980 DOI: 10.1002/Cam4.387 |
0.342 |
|
| 2015 |
Adams AK, Hallenbeck GE, Casper KA, Patil YJ, Wilson KM, Kimple RJ, Lambert PF, Witte DP, Xiao W, Gillison ML, Wikenheiser-Brokamp KA, Wise-Draper TM, Wells SI. DEK promotes HPV-positive and -negative head and neck cancer cell proliferation. Oncogene. 34: 868-77. PMID 24608431 DOI: 10.1038/Onc.2014.15 |
0.33 |
|
| 2015 |
Wong SJ, Li L, Hess LM, Chen AY, Curran WJ, Harari PM, Kimple RJ, Murphy BA, Opincar LL, Garden AS. Utilization and outcomes of low dose versus high dose cisplatin in head and neck cancer patients receiving concurrent radiation. Journal of Clinical Oncology. 33: 6019-6019. DOI: 10.1200/Jco.2015.33.15_Suppl.6019 |
0.324 |
|
| 2015 |
Swick AD, Gunderson D, Smith M, Blitzer G, Stein A, Nickel KP, Kimple RJ. Abstract 3603: Molecular targeting of cetuximab resistant head and neck cancer Cancer Research. 75: 3603-3603. DOI: 10.1158/1538-7445.Am2015-3603 |
0.372 |
|
| 2015 |
Bailey A, Fowler T, Nickel KP, Bednarz B, Kimple RJ. Abstract 1801: Biological validation of a novel high-throughput irradiator for predictive radiation sensitivity bioassays Cancer Research. 75: 1801-1801. DOI: 10.1158/1538-7445.Am2015-1801 |
0.304 |
|
| 2015 |
Swick A, Prabakaran J, Fisher M, Stein A, Gunderson D, Nickel K, Kimple R. Abstract A122: Pre-clinical investigation of resistance to molecular targeted therapeutics in head and neck cancer Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-A122 |
0.37 |
|
| 2015 |
Campos D, Peeters W, Nickel K, Eliceiri K, Kimple R, Kogel AVD, Kissick M. SU-C-303-02: Correlating Metabolic Response to Radiation Therapy with HIF-1alpha Expression Medical Physics. 42: 3197-3197. DOI: 10.1118/1.4923819 |
0.314 |
|
| 2014 |
Fowler TL, Martin JA, Shepard AJ, Bailey AM, Nickel KP, Kimple RJ, Bednarz BP. WE-E-BRE-03: Biological Validation of a Novel High-Throughput Irradiator for Predictive Radiation Sensitivity Bioassays. Medical Physics. 41: 504. PMID 28037084 DOI: 10.1118/1.4889432 |
0.317 |
|
| 2014 |
Zhang K, Jones L, Lim S, Maher CA, Adkins D, Lewis J, Kimple RJ, Fertig EJ, Chung CH, Van Tine BA, Ellis MJ, Herrlich A, Michel LS. Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC. Oncotarget. 5: 9281-94. PMID 25238142 DOI: 10.18632/Oncotarget.2423 |
0.348 |
|
| 2014 |
Brand TM, Iida M, Stein AP, Corrigan KL, Braverman CM, Luthar N, Toulany M, Gill PS, Salgia R, Kimple RJ, Wheeler DL. AXL mediates resistance to cetuximab therapy. Cancer Research. 74: 5152-64. PMID 25136066 DOI: 10.1158/0008-5472.Can-14-0294 |
0.329 |
|
| 2014 |
Stein AP, Saha S, Liu CZ, Hartig GK, Lambert PF, Kimple RJ. Influence of handling conditions on the establishment and propagation of head and neck cancer patient derived xenografts. Plos One. 9: e100995. PMID 24967635 DOI: 10.1371/Journal.Pone.0100995 |
0.305 |
|
| 2014 |
Stein AP, Saha S, Yu M, Kimple RJ, Lambert PF. Prevalence of human papillomavirus in oropharyngeal squamous cell carcinoma in the United States across time. Chemical Research in Toxicology. 27: 462-9. PMID 24641254 DOI: 10.1021/Tx500034C |
0.303 |
|
| 2014 |
Kimple RJ, Harari PM. Is radiation dose reduction the right answer for HPV-positive head and neck cancer? Oral Oncology. 50: 560-4. PMID 24134946 DOI: 10.1016/J.Oraloncology.2013.09.015 |
0.326 |
|
| 2014 |
Martin JA, Gunderson D, Kimple RJ. Abstract 4899: Small proline rich protein 3 (SPRR3) is a potential mediator of radiation resistance in HPV negative head and neck squamous cell carcinoma Cancer Research. 74: 4899-4899. DOI: 10.1158/1538-7445.Am2014-4899 |
0.328 |
|
| 2014 |
Law ADT, Blitzer GC, Smith MA, Armstrong EA, Kimple RJ. Abstract 4243: EGFR inhibition causes growth delay and induces apoptosis in HPV-positive head and neck cancer Cancer Research. 74: 4243-4243. DOI: 10.1158/1538-7445.Am2014-4243 |
0.328 |
|
| 2014 |
Hong J, Johannsen E, Boon Jd, Horswill M, Ahlquist P, Lambert P, Kimple R. Patterns of HPV Integration and Cancer-Associated Mutations in Head-and-Neck Cancer Patient-Derived Xenografts International Journal of Radiation Oncology*Biology*Physics. 88: 516. DOI: 10.1016/J.Ijrobp.2013.11.166 |
0.326 |
|
| 2013 |
Kimple RJ, Smith MA, Blitzer GC, Torres AD, Martin JA, Yang RZ, Peet CR, Lorenz LD, Nickel KP, Klingelhutz AJ, Lambert PF, Harari PM. Enhanced radiation sensitivity in HPV-positive head and neck cancer. Cancer Research. 73: 4791-800. PMID 23749640 DOI: 10.1158/0008-5472.Can-13-0587 |
0.314 |
|
| 2013 |
Kimple RJ, Harari PM, Torres AD, Yang RZ, Soriano BJ, Yu M, Armstrong EA, Blitzer GC, Smith MA, Lorenz LD, Lee D, Yang DT, McCulloch TM, Hartig GK, Lambert PF. Development and characterization of HPV-positive and HPV-negative head and neck squamous cell carcinoma tumorgrafts. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 855-64. PMID 23251001 DOI: 10.1158/1078-0432.Ccr-12-2746 |
0.302 |
|
| 2013 |
Smith MA, Blitzer GC, Torres AD, Armstrong EA, Lambert PF, Harari PM, Kimple RJ. Abstract 73: Preclinical evaluation of chemoradiation with cetuximab HPV-positive head and neck cancer suggests significant radiosensitization. Cancer Research. 73: 73-73. DOI: 10.1158/1538-7445.Am2013-73 |
0.368 |
|
| 2013 |
Blitzer GC, Smith MA, Torres AD, Armstrong EA, Harari PM, Lambert PF, Kimple RJ. Abstract 5474: Epidermal growth factor inhibition of HPV positive head and neck cancer cells and primary tumorgrafts results in significant growth inhibition mediated by apoptosis. Cancer Research. 73: 5474-5474. DOI: 10.1158/1538-7445.Am2013-5474 |
0.339 |
|
| 2013 |
Fowler TL, Ludwig KD, Djavadian R, Bednarz BP, Kimple RJ. Abstract 1664: A delicate balance between radiation-induced autophagy and apoptosis in HPV-positive head and neck cancer. Cancer Research. 73: 1664-1664. DOI: 10.1158/1538-7445.Am2013-1664 |
0.335 |
|
| 2012 |
Kimple RJ, Horton JK, Livasy CA, Shields JM, Lawrence JA, Chiu WM, Ivanova A, Ollila DW, Carey LA, Halle JS, Sartor CI, Dees EC. Phase I study and biomarker analysis of lapatinib and concurrent radiation for locally advanced breast cancer. The Oncologist. 17: 1496-503. PMID 23006498 DOI: 10.1634/Theoncologist.2012-0256 |
0.313 |
|
| 2012 |
Kimple AJ, Torres AD, Yang RZ, Kimple RJ. HPV-associated head and neck cancer: molecular and nano-scale markers for prognosis and therapeutic stratification. Sensors (Basel, Switzerland). 12: 5159-69. PMID 22666080 DOI: 10.3390/S120405159 |
0.332 |
|
| 2012 |
Torres AD, Kimple RJ, Yang RZ, Soriano B, Armstrong EA, Harari PM, Lambert PF. Abstract 2356: Establishment of HPV-positive and HPV-negative head and neck cancer tumorgrafts directly from patient biopsies Cancer Research. 72: 2356-2356. DOI: 10.1158/1538-7445.Am2012-2356 |
0.341 |
|
| 2012 |
Kimple RJ, Blitzer GC, Torres AD, Yang RZ, Lorenz LD, Armstrong EA, Soriano BJ, Lambert PF, Harari PM. Abstract 2352: Molecular profiles of head and neck cancer tumorgrafts Cancer Research. 72: 2352-2352. DOI: 10.1158/1538-7445.Am2012-2352 |
0.324 |
|
| 2011 |
Harris SL, Thorne LB, Seaman WT, Hayes DN, Couch ME, Kimple RJ. Association of p16(INK4a) overexpression with improved outcomes in young patients with squamous cell cancers of the oral tongue. Head & Neck. 33: 1622-7. PMID 21990227 DOI: 10.1002/Hed.21650 |
0.312 |
|
| 2011 |
Kimple RJ, Yang RZ, Armstrong EA, Lambert PF, Harari PM. Abstract 2721: Comparative responses of HPV-positive vs HPV-negative head and neck cancer cells to radiation and/or chemotherapeutic drugs Cancer Research. 71: 2721-2721. DOI: 10.1158/1538-7445.Am2011-2721 |
0.329 |
|
| 2010 |
Kimple RJ. Strategizing the clone wars: pharmacological control of cellular sensitivity to radiation. Molecular Interventions. 10: 341-53. PMID 21263160 DOI: 10.1124/Mi.10.6.3 |
0.318 |
|
| 2010 |
Hutsell SQ, Kimple RJ, Siderovski DP, Willard FS, Kimple AJ. High-affinity immobilization of proteins using biotin- and GST-based coupling strategies. Methods in Molecular Biology (Clifton, N.J.). 627: 75-90. PMID 20217614 DOI: 10.1007/978-1-60761-670-2_4 |
0.526 |
|
| 2010 |
Kimple RJ, Vaseva AV, Cox AD, Baerman KM, Calvo BF, Tepper JE, Shields JM, Sartor CI. Radiosensitization of epidermal growth factor receptor/HER2-positive pancreatic cancer is mediated by inhibition of Akt independent of ras mutational status. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 912-23. PMID 20103665 DOI: 10.1158/1078-0432.Ccr-09-1324 |
0.331 |
|
| 2010 |
Harris SL, Kimple RJ, Hayes DN, Couch ME, Rosenman JG. Never-smokers, never-drinkers: unique clinical subgroup of young patients with head and neck squamous cell cancers. Head & Neck. 32: 499-503. PMID 19691028 DOI: 10.1002/Hed.21220 |
0.607 |
|
| 2009 |
Sambade MJ, Camp JT, Kimple RJ, Sartor CI, Shields JM. Mechanism of lapatinib-mediated radiosensitization of breast cancer cells is primarily by inhibition of the Raf>MEK>ERK mitogen-activated protein kinase cascade and radiosensitization of lapatinib-resistant cells restored by direct inhibition of MEK. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 93: 639-44. PMID 19853943 DOI: 10.1016/J.Radonc.2009.09.006 |
0.324 |
|
| 2009 |
Willard FS, Willard MD, Kimple AJ, Soundararajan M, Oestreich EA, Li X, Sowa NA, Kimple RJ, Doyle DA, Der CJ, Zylka MJ, Snider WD, Siderovski DP. Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector. Plos One. 4: e4884. PMID 19319189 DOI: 10.1371/Journal.Pone.0004884 |
0.742 |
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| 2009 |
Sambade MJ, Kimple RJ, Camp T, Peters E, Livasy CA, Sartor CI, Shields JM. Abstract B73: Lapatinib‐mediated radiosensitization of EGFR+/basal breast cancer correlates withERK inhibition in vivo and requires MEK/ERK inhibition in vitro Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B73 |
0.338 |
|
| 2009 |
Harris SL, Kimple RJ, Feinberg NH, Seaman WT, Hayes DN, Thorne LB, Couch ME. P16ink4a Over-expression is Associated with Improved Outcomes in Young Patients with Squamous Cell Cancers of the Oral Tongue International Journal of Radiation Oncology Biology Physics. 75. DOI: 10.1016/J.Ijrobp.2009.07.888 |
0.307 |
|
| 2008 |
Harris SL, Kimple RJ, Hayes DN, Couch ME, Rosenman JG. A Unique Subgroup of Young Patients with Head and Neck Cancer International Journal of Radiation Oncology Biology Physics. 72. DOI: 10.1016/J.Ijrobp.2008.06.1323 |
0.319 |
|
| 2007 |
Sammond DW, Eletr ZM, Purbeck C, Kimple RJ, Siderovski DP, Kuhlman B. Structure-based protocol for identifying mutations that enhance protein-protein binding affinities. Journal of Molecular Biology. 371: 1392-404. PMID 17603074 DOI: 10.1016/J.Jmb.2007.05.096 |
0.56 |
|
| 2005 |
McCudden CR, Willard FS, Kimple RJ, Johnston CA, Hains MD, Jones MB, Siderovski DP. G alpha selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN. Biochimica Et Biophysica Acta. 1745: 254-64. PMID 15946753 DOI: 10.1016/J.Bbamcr.2005.05.002 |
0.668 |
|
| 2005 |
Webb CK, McCudden CR, Willard FS, Kimple RJ, Siderovski DP, Oxford GS. D2 dopamine receptor activation of potassium channels is selectively decoupled by Galpha-specific GoLoco motif peptides. Journal of Neurochemistry. 92: 1408-18. PMID 15748159 DOI: 10.1111/J.1471-4159.2004.02997.X |
0.568 |
|
| 2005 |
McCudden CR, Hains MD, Kimple RJ, Siderovski DP, Willard FS. G-protein signaling: back to the future. Cellular and Molecular Life Sciences : Cmls. 62: 551-77. PMID 15747061 DOI: 10.1007/S00018-004-4462-3 |
0.594 |
|
| 2004 |
Martin-McCaffrey L, Willard FS, Oliveira-dos-Santos AJ, Natale DR, Snow BE, Kimple RJ, Pajak A, Watson AJ, Dagnino L, Penninger JM, Siderovski DP, D'Souza SJ. RGS14 is a mitotic spindle protein essential from the first division of the mammalian zygote. Developmental Cell. 7: 763-9. PMID 15525537 DOI: 10.1016/J.Devcel.2004.10.004 |
0.584 |
|
| 2004 |
Kimple RJ, Willard FS, Siderovski DP. Purification and in vitro functional analyses of RGS12 and RGS14 GoLoco motif peptides. Methods in Enzymology. 390: 416-36. PMID 15488192 DOI: 10.1016/S0076-6879(04)90026-2 |
0.578 |
|
| 2004 |
Willard FS, Kimple RJ, Kimple AJ, Johnston CA, Siderovski DP. Fluorescence-based assays for RGS box function. Methods in Enzymology. 389: 56-71. PMID 15313559 DOI: 10.1016/S0076-6879(04)89004-9 |
0.68 |
|
| 2004 |
Willard FS, Kimple RJ, Siderovski DP. Return of the GDI: the GoLoco motif in cell division. Annual Review of Biochemistry. 73: 925-51. PMID 15189163 DOI: 10.1146/Annurev.Biochem.73.011303.073756 |
0.583 |
|
| 2004 |
Kimple RJ, Willard FS, Hains MD, Jones MB, Nweke GK, Siderovski DP. Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif. The Biochemical Journal. 378: 801-8. PMID 14656218 DOI: 10.1042/Bj20031686 |
0.589 |
|
| 2003 |
Rojas RJ, Kimple RJ, Rossman KL, Siderovski DP, Sondek J. Established and emerging fluorescence-based assays for G-protein function: Ras-superfamily GTPases. Combinatorial Chemistry & High Throughput Screening. 6: 409-18. PMID 12769685 DOI: 10.2174/138620703106298509 |
0.572 |
|
| 2003 |
Kimple RJ, Jones MB, Shutes A, Yerxa BR, Siderovski DP, Willard FS. Established and emerging fluorescence-based assays for G-protein function: heterotrimeric G-protein alpha subunits and regulator of G-protein signaling (RGS) proteins. Combinatorial Chemistry & High Throughput Screening. 6: 399-407. PMID 12769684 DOI: 10.2174/138620703106298491 |
0.596 |
|
| 2003 |
Colombo K, Grill SW, Kimple RJ, Willard FS, Siderovski DP, Gönczy P. Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos. Science (New York, N.Y.). 300: 1957-61. PMID 12750478 DOI: 10.1126/Science.1084146 |
0.534 |
|
| 2002 |
Kimple RJ, Willard FS, Siderovski DP. The GoLoco motif: heralding a new tango between G protein signaling and cell division. Molecular Interventions. 2: 88-100. PMID 14993354 DOI: 10.1124/Mi.2.2.88 |
0.597 |
|
| 2002 |
Kimple RJ, Kimple ME, Betts L, Sondek J, Siderovski DP. Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits. Nature. 416: 878-81. PMID 11976690 DOI: 10.1038/416878A |
0.593 |
|
| 2001 |
Kimple RJ, De Vries L, Tronchère H, Behe CI, Morris RA, Gist Farquhar M, Siderovski DP. RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity. The Journal of Biological Chemistry. 276: 29275-81. PMID 11387333 DOI: 10.1074/Jbc.M103208200 |
0.563 |
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