Isaac Donkor - Publications

Affiliations: 
University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Pharmaceutical Chemistry, Organic Chemistry, Pharmacology

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Donkor IO, Xu J, Liu J, Cameron K. Synthesis and antiproliferative activity of sulfonamide-based peptidomimetic calpain inhibitors. Bioorganic & Medicinal Chemistry. 115433. PMID 32199690 DOI: 10.1016/j.bmc.2020.115433  0.461
2010 Saab NH, Donkor IO, Rodriguez L, Kador PF, Miller DD. ChemInform Abstract: Phenylsulfonylnitromethanes as Potent Irreversible Inhibitors of Aldose Reductase. Cheminform. 31: no-no. DOI: 10.1002/chin.200006244  0.422
2010 Donkor IO, Abdel-Ghany YS, Kador PF, Mizoguchi T, Bartoszko-Malik A, Miller DD. ChemInform Abstract: Synthesis and Biological Activity of Aldose Reductase Inhibitors with Michael Acceptor Substituents. Cheminform. 30: no-no. DOI: 10.1002/chin.199934174  0.383
2010 DONKOR IO, ABDEL-GHANY YS, KADOR PF, MIZOGUCHI T, BARTOSZKO-MALIK A, MILLER DD. ChemInform Abstract: Synthesis and Biological Activities of Aldose Reductase Inhibitors Bearing Acyl Benzenesulfonamides as Carboxylic Acid Surrogates. Cheminform. 29: no-no. DOI: 10.1002/chin.199828119  0.357
2008 Donkor IO, Korukonda R. Synthesis and calpain inhibitory activity of peptidomimetic compounds with constrained amino acids at the P2 position. Bioorganic & Medicinal Chemistry Letters. 18: 4806-8. PMID 18694642 DOI: 10.1016/J.Bmcl.2008.07.094  0.723
2008 Donkor IO, Assefa H, Liu J. Structural basis for the potent calpain inhibitory activity of peptidyl alpha-ketoacids. Journal of Medicinal Chemistry. 51: 4346-50. PMID 18636690 DOI: 10.1021/jm800182c  0.379
2006 Korukonda R, Guan N, Dalton JT, Liu J, Donkor IO. Synthesis, calpain inhibitory activity, and cytotoxicity of P2-substituted proline and thiaproline peptidyl aldehydes and peptidyl alpha-ketoamides. Journal of Medicinal Chemistry. 49: 5282-90. PMID 16913717 DOI: 10.1021/Jm050849W  0.725
2006 Huang TL, Vanden Eynde JJ, Mayence A, Donkor IO, Khan SI, Tekwani BL. Anti-plasmodial and anti-leishmanial activity of conformationally restricted pentamidine congeners. The Journal of Pharmacy and Pharmacology. 58: 1033-42. PMID 16872549 DOI: 10.1211/jpp.58.8.0003  0.301
2006 Guan N, Korukonda R, Hurh E, Schmittgen TD, Donkor IO, Dalton JT. Apoptosis induced by novel aldehyde calpain inhibitors in human tumor cell lines. International Journal of Oncology. 29: 655-63. PMID 16865282 DOI: 10.3892/Ijo.29.3.655  0.701
2006 Sanders ML, Donkor IO. A novel series of urea-based peptidomimetic calpain inhibitors. Bioorganic & Medicinal Chemistry Letters. 16: 1965-8. PMID 16412635 DOI: 10.1016/j.bmcl.2005.12.068  0.716
2005 Vanden Eynde JJ, Mayence A, Johnson MT, Huang TL, Collins MS, Rebholz S, Walzer PD, Cushion MT, Donkor IO. Antitumor and anti-Pneumocystis carinii activities of novel bisbenzamidines Medicinal Chemistry Research. 14: 143-157. DOI: 10.1007/S00044-005-0130-2  0.347
2004 Donkor IO, Han J, Zheng X. Design, synthesis, molecular modeling studies, and calpain inhibitory activity of novel alpha-ketoamides incorporating polar residues at the P1'-position. Journal of Medicinal Chemistry. 47: 72-9. PMID 14695821 DOI: 10.1021/jm0301336  0.307
2003 Donkor IO, Li H, Queener SF. Synthesis and DHFR inhibitory activity of a series of 6-substituted-2,4-diaminothieno[2,3-d]pyrimidines. European Journal of Medicinal Chemistry. 38: 605-11. PMID 12832132 DOI: 10.1016/S0223-5234(03)00101-6  0.32
2003 Donkor IO, Korukonda R, Huang TL, LeCour L. Peptidyl aldehyde inhibitors of calpain incorporating P2-proline mimetics. Bioorganic & Medicinal Chemistry Letters. 13: 783-4. PMID 12617890 DOI: 10.1016/S0960-894X(03)00021-0  0.734
2002 Sanders ML, Donkor IO. THE SYNTHESIS OF A SERIES OF 3,5-DISUBSTITUTED TETRAHYDRO- 1H-IMIDAZOLE-2,4-DIONES UTILIZING LITHIUM ALUMINUM HYDRIDE Synthetic Communications. 32: 1015-1021. DOI: 10.1081/Scc-120003149  0.332
2001 Donkor IO, Sanders ML. Synthesis of a reported calpain inhibitor isolated from Streptomyces griseus. Bioorganic & Medicinal Chemistry Letters. 11: 2647-9. PMID 11551769 DOI: 10.1016/S0960-894X(01)00524-8  0.685
2000 Donkor IO, Zheng X, Miller DD. Synthesis and calpain inhibitory activity of alpha-ketoamides with 2,3-methanoleucine stereoisomers at the P2 position. Bioorganic & Medicinal Chemistry Letters. 10: 2497-500. PMID 11086714 DOI: 10.1016/S0960-894X(00)00518-7  0.491
2000 Donkor IO. A survey of calpain inhibitors. Current Medicinal Chemistry. 7: 1171-88. PMID 11032966 DOI: 10.2174/0929867003374129  0.498
2000 Donkor IO, Zheng X, Han J, Miller DD. Asymmetric synthesis of 2,3-methanoleucine stereoisomers from common intermediates. Chirality. 12: 551-7. PMID 10861954 DOI: 10.1002/1520-636X(2000)12:7<551::Aid-Chir1>3.0.Co;2-C  0.334
1999 Tao B, Huang TL, Zhang Q, Jackson L, Queener SF, Donkor IO. Synthesis and anti-Pneumocystis carinii activity of conformationally restricted analogues of pentamidine European Journal of Medicinal Chemistry. 34: 531-538. DOI: 10.1016/S0223-5234(99)80102-0  0.344
1999 Donkor IO, Abdel-Ghany YS, Kador PF, Mizoguchi T, Bartoszko-Malik A, Miller DD. Synthesis and biological activity of aldose reductase inhibitors with Michael acceptor substituents European Journal of Medicinal Chemistry. 34: 235-243. DOI: 10.1016/S0223-5234(99)80056-7  0.392
1998 Donkor IO, Zhou X, Schmidt J, Agrawal KC, Kishore V. Synthesis and radioprotective effects of adamantyl substituted 1,4-dihydropyridine derivatives. Bioorganic & Medicinal Chemistry. 6: 563-8. PMID 9629469 DOI: 10.1016/S0968-0896(98)00017-0  0.326
1998 Donkor IO, Abdel-Ghany YS, Kador PF, Mizoguchi T, Bartoszko-Malik A, Miller DD. Synthesis and biological activities of aldose reductase inhibitors bearing acyl benzenesulfonamides as carboxylic acid surrogates European Journal of Medicinal Chemistry. 33: 15-22. DOI: 10.1016/S0223-5234(99)80071-3  0.361
1996 Donkor IO, Devraj R, Queener SF, Barrows LR, Gangjee A. Synthesis of a Series of Diaminobenzo[f]- And Diaminobenzo[h]pyrimido[4,5-b]quinolines as 5-Deaza Tetracyclic Nonclassical Antifolates Journal of Heterocyclic Chemistry. 33: 1653-1660. DOI: 10.1002/Jhet.5570330618  0.361
1994 Donkor IO, Tidwell RR, Jones SK. Pentamidine congeners. 2. 2-butene-bridged aromatic diamidines and diimidazolines as potential anti-pneumocystis carinii pneumonia agents Journal of Medicinal Chemistry®. 37: 4554-4557. PMID 7799405 DOI: 10.1021/Jm00052A014  0.304
1991 Gangjee A, Donkor IO, Kisliuk RL, Gaumont Y, Thorndike J. Synthesis and biological activity of 5,11-methylenetetrahydro-5-deazahomofolic acid Journal of Medicinal Chemistry. 34: 611-616. PMID 1995884 DOI: 10.1021/Jm00106A022  0.521
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