Isaac Donkor - Publications

University of Tennessee Health Science Center, Memphis, TN, United States 
Pharmaceutical Chemistry, Organic Chemistry, Pharmacology

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Donkor IO, Xu J, Liu J, Cameron K. Synthesis and antiproliferative activity of sulfonamide-based peptidomimetic calpain inhibitors. Bioorganic & Medicinal Chemistry. 115433. PMID 32199690 DOI: 10.1016/j.bmc.2020.115433  0.36
2011 Sampson JJ, Donkor IO, Huang TL, Adunyah SE. Novel piperazine induces apoptosis in U937 cells. International Journal of Biochemistry and Molecular Biology. 2: 78-88. PMID 21968418  0.36
2008 Donkor IO, Korukonda R. Synthesis and calpain inhibitory activity of peptidomimetic compounds with constrained amino acids at the P2 position. Bioorganic & Medicinal Chemistry Letters. 18: 4806-8. PMID 18694642 DOI: 10.1016/j.bmcl.2008.07.094  1
2008 Donkor IO, Assefa H, Liu J. Structural basis for the potent calpain inhibitory activity of peptidyl alpha-ketoacids. Journal of Medicinal Chemistry. 51: 4346-50. PMID 18636690 DOI: 10.1021/jm800182c  0.36
2007 Huang TL, Bacchi CJ, Kode NR, Zhang Q, Wang G, Yartlet N, Rattendi D, Londono I, Mazumder L, Vanden Eynde JJ, Mayence A, Donkor IO. Trypanocidal activity of piperazine-linked bisbenzamidines and bisbenzamidoxime, an orally active prodrug. International Journal of Antimicrobial Agents. 30: 555-61. PMID 17920820 DOI: 10.1016/j.ijantimicag.2007.07.021  0.36
2006 Korukonda R, Guan N, Dalton JT, Liu J, Donkor IO. Synthesis, calpain inhibitory activity, and cytotoxicity of P2-substituted proline and thiaproline peptidyl aldehydes and peptidyl alpha-ketoamides. Journal of Medicinal Chemistry. 49: 5282-90. PMID 16913717 DOI: 10.1021/jm050849w  1
2006 Huang TL, Vanden Eynde JJ, Mayence A, Donkor IO, Khan SI, Tekwani BL. Anti-plasmodial and anti-leishmanial activity of conformationally restricted pentamidine congeners. The Journal of Pharmacy and Pharmacology. 58: 1033-42. PMID 16872549 DOI: 10.1211/jpp.58.8.0003  0.36
2006 Guan N, Korukonda R, Hurh E, Schmittgen TD, Donkor IO, Dalton JT. Apoptosis induced by novel aldehyde calpain inhibitors in human tumor cell lines. International Journal of Oncology. 29: 655-63. PMID 16865282  1
2006 Sanders ML, Donkor IO. A novel series of urea-based peptidomimetic calpain inhibitors. Bioorganic & Medicinal Chemistry Letters. 16: 1965-8. PMID 16412635 DOI: 10.1016/j.bmcl.2005.12.068  0.92
2003 Donkor IO, Li H, Queener SF. Synthesis and DHFR inhibitory activity of a series of 6-substituted-2,4-diaminothieno[2,3-d]pyrimidines. European Journal of Medicinal Chemistry. 38: 605-11. PMID 12832132 DOI: 10.1016/S0223-5234(03)00101-6  0.92
2003 Donkor IO, Huang TL, Tao B, Rattendi D, Lane S, Vargas M, Goldberg B, Bacchi C. Trypanocidal activity of conformationally restricted pentamidine congeners. Journal of Medicinal Chemistry. 46: 1041-8. PMID 12620080 DOI: 10.1021/jm020375q  0.36
2003 Donkor IO, Korukonda R, Huang TL, LeCour L. Peptidyl aldehyde inhibitors of calpain incorporating P2-proline mimetics. Bioorganic & Medicinal Chemistry Letters. 13: 783-4. PMID 12617890  1
2001 Donkor IO, Sanders ML. Synthesis of a reported calpain inhibitor isolated from Streptomyces griseus. Bioorganic & Medicinal Chemistry Letters. 11: 2647-9. PMID 11551769 DOI: 10.1016/S0960-894X(01)00524-8  0.92
1993 Donkor IO, Jones SK, Tidwell RR. Pentamidine Congeners 1: Synthesis of Cis- and Trans-Butamidine Analogues As Anti-Pneumocystis carinii Pneumonia Agents. Bioorganic & Medicinal Chemistry Letters. 3: 1137-1140. PMID 21451734 DOI: 10.1016/S0960-894X(00)80302-9  0.92
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