Isaac Donkor - Related publications

Affiliations: 
University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Pharmaceutical Chemistry, Organic Chemistry, Pharmacology
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Peng Z, Wang G, Zeng QH, Li Y, Wu Y, Liu H, Wang JJ, Zhao Y. Synthesis, antioxidant and anti-tyrosinase activity of 1,2,4-triazole hydrazones as antibrowning agents. Food Chemistry. 341: 128265. PMID 33031957 DOI: 10.1016/j.foodchem.2020.128265   
2020 Xia L, Zhang Y, Zhang J, Lin S, Zhang K, Tian H, Dong Y, Xu H. Identification of Novel Thiazolo[5,4-]Pyridine Derivatives as Potent Phosphoinositide 3-Kinase Inhibitors. Molecules (Basel, Switzerland). 25. PMID 33053730 DOI: 10.3390/molecules25204630   
2020 Kanhed AM, Patel DV, Patel NR, Sinha A, Thakor PS, Patel KB, Prajapati NK, Patel KV, Yadav MR. Indoloquinoxaline derivatives as promising multi-functional anti-Alzheimer agents. Journal of Biomolecular Structure & Dynamics. 1-18. PMID 33111617 DOI: 10.1080/07391102.2020.1840441   
2020 Kanhed AM, Patel DV, Patel NR, Sinha A, Thakor PS, Patel KB, Prajapati NK, Patel KV, Yadav MR. Indoloquinoxaline derivatives as promising multi-functional anti-Alzheimer agents. Journal of Biomolecular Structure & Dynamics. 1-18. PMID 33111617 DOI: 10.1080/07391102.2020.1840441   
2020 Li D, Liu C, Jiang X, Lin Y, Zhang J, Li Y, You X, Jiang W, Chen M, Xu Y, Si S. Design, synthesis, and evaluation of substituted 2-acylamide-1,3-benzo[d]zole analogues as agents against MDR- and XDR-MTB. European Journal of Medicinal Chemistry. 112898. PMID 33069433 DOI: 10.1016/j.ejmech.2020.112898   
2020 Zeng F, Li S, Yang G, Luo Y, Qi T, Liang Y, Yang T, Zhang L, Wang R, Zhu L, Li H, Xu X. Design, synthesis, molecular modeling, and biological evaluation of acrylamide derivatives as potent inhibitors of human dihydroorotate dehydrogenase for the treatment of rheumatoid arthritis. Acta Pharmaceutica Sinica. B. PMID 33078092 DOI: 10.1016/j.apsb.2020.10.008   
2020 Cirri D, Schirmeister T, Seo EJ, Efferth T, Massai L, Messori L, Micale N. Antiproliferative Properties of a Few Auranofin-Related Gold(I) and Silver(I) Complexes in Leukemia Cells and their Interferences with the Ubiquitin Proteasome System. Molecules (Basel, Switzerland). 25. PMID 32998355 DOI: 10.3390/molecules25194454   
2020 Chen J, Li Y, Cao J, Huang J, Jiang C, Dai X, Huang G. Adiantic acid, a new unsaturated fatty acid with a cyclopropane moiety from L. Natural Product Research. 1-7. PMID 33016135 DOI: 10.1080/14786419.2020.1827405   
2020 Monroy-Cárdenas M, Méndez D, Trostchansky A, Martínez-Cifuentes M, Araya-Maturana R, Fuentes E. Synthesis and Biological Evaluation of Thio-Derivatives of 2-Hydroxy-1,4-Naphthoquinone (Lawsone) as Novel Antiplatelet Agents. Frontiers in Chemistry. 8: 533. PMID 32850615 DOI: 10.3389/fchem.2020.00533   
2020 Monroy-Cárdenas M, Méndez D, Trostchansky A, Martínez-Cifuentes M, Araya-Maturana R, Fuentes E. Synthesis and Biological Evaluation of Thio-Derivatives of 2-Hydroxy-1,4-Naphthoquinone (Lawsone) as Novel Antiplatelet Agents. Frontiers in Chemistry. 8: 533. PMID 32850615 DOI: 10.3389/fchem.2020.00533   
2020 Zhang Y, Liu J, Chen M, Fan Y, Li M, Wang A, Liu G, Xu Y, Ren X, Xiao Y. Isolation of a new monoterpenoid glycoside from Anhua dark tea based on an NMR-guided method and its cytotoxic activity against MDA-MB-231 and SH-SY5Y cell lines. Natural Product Research. 1-6. PMID 33146029 DOI: 10.1080/14786419.2020.1839465   
2020 Ferreira RJ, Gajdács M, Kincses A, Spengler G, Dos Santos DJVA, Ferreira MU. Nitrogen-containing naringenin derivatives for reversing multidrug resistance in cancer. Bioorganic & Medicinal Chemistry. 28: 115798. PMID 33038666 DOI: 10.1016/j.bmc.2020.115798   
2020 Fouda AM, Hassan AH, Eliwa EM, Ahmed HEA, Al-Dies AM, Omar AM, Nassar HS, Halawa AH, Aljuhani N, El-Agrody AM. Targeted potent antimicrobial benzochromene-based analogues: Synthesis, computational studies, and inhibitory effect against 14α-Demethylase and DNA Gyrase. Bioorganic Chemistry. 105: 104387. PMID 33130344 DOI: 10.1016/j.bioorg.2020.104387   
2020 Adalat B, Rahim F, Taha M, Alshamrani FJ, Anouar EH, Uddin N, Shah SAA, Ali Z, Zakaria ZA. Synthesis of Benzimidazole-Based Analogs as Anti Alzheimer's Disease Compounds and Their Molecular Docking Studies. Molecules (Basel, Switzerland). 25. PMID 33092223 DOI: 10.3390/molecules25204828   
2020 Al-Salem HS, Arifuzzaman M, Alkahtani HM, Abdalla AN, Issa IS, Alqathama A, Albalawi FS, Rahman AFMM. A Series of Isatin-Hydrazones with Cytotoxic Activity and CDK2 Kinase Inhibitory Activity: A Potential Type II ATP Competitive Inhibitor. Molecules (Basel, Switzerland). 25. PMID 32992673 DOI: 10.3390/molecules25194400   
2020 Abd Alhameed R, Almarhoon Z, N Sholkamy E, Ali Khan S, Ul-Haq Z, Sharma A, G de la Torre B, Albericio F, El-Faham A. Novel 4,6-Disubstituted -Triazin-2-yl Amino Acid Derivatives as Promising Antifungal Agents. Journal of Fungi (Basel, Switzerland). 6. PMID 33096851 DOI: 10.3390/jof6040237   
2020 Jia F, Lei H, Chen Y, Li T, Xing L, Cao Z, Zhai X. Structure-based linker exploration: Discovery of 1-ethyl-1H-indole analogs as novel ATX inhibitors. Bioorganic & Medicinal Chemistry. 28: 115795. PMID 33032188 DOI: 10.1016/j.bmc.2020.115795   
2020 Tonelli M, Sparatore A, Basilico N, Cavicchini L, Parapini S, Tasso B, Laurini E, Pricl S, Boido V, Sparatore F. Quinolizidine-Derived Lucanthone and Amitriptyline Analogues Endowed with Potent Antileishmanial Activity. Pharmaceuticals (Basel, Switzerland). 13. PMID 33113777 DOI: 10.3390/ph13110339   
2020 Tocco G, Esposito F, Caboni P, Laus A, Beutler JA, Wilson JA, Corona A, Le Grice SFJ, Tramontano E. Scaffold hopping and optimisation of 3',4'-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H. Journal of Enzyme Inhibition and Medicinal Chemistry. 35: 1953-1963. PMID 33143469 DOI: 10.1080/14756366.2020.1835884   
2020 Zhao YS, Qian XK, Guan XQ, Song PF, Song YQ, He RJ, Sun MR, Wang XY, Zou LW, Ge GB. Discovery of natural alkaloids as potent and selective inhibitors against human carboxylesterase 2. Bioorganic Chemistry. 105: 104367. PMID 33080495 DOI: 10.1016/j.bioorg.2020.104367   
2020 Pitsillou E, Liang J, Karagiannis C, Ververis K, Darmawan KK, Ng K, Hung A, Karagiannis TC. Interaction of small molecules with the SARS-CoV-2 main protease in silico and in vitro validation of potential lead compounds using an enzyme-linked immunosorbent assay. Computational Biology and Chemistry. 89: 107408. PMID 33137690 DOI: 10.1016/j.compbiolchem.2020.107408   
2020 Zhang ZP, Xue WY, Hu JX, Xiong DC, Wu YF, Ye XS. Novel carbohydrate-triazole derivatives as potential α-glucosidase inhibitors. Chinese Journal of Natural Medicines. 18: 729-737. PMID 33039052 DOI: 10.1016/S1875-5364(20)60013-9   
2020 Inoue M, Kamiya K, Miura K, Itoh H. Divergent Solid-Phase Synthesis and Biological Evaluation of Yaku'amide B and Its Seven E/Z Isomers. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 33022828 DOI: 10.1002/chem.202003858   
2020 Lu GL, Tong AST, Conole D, Sutherland HS, Choi PJ, Franzblau SG, Upton AM, Lotlikar MU, Cooper CB, Denny WA, Palmer BD. Synthesis and structure-activity relationships for tetrahydroisoquinoline-based inhibitors of Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry. 28: 115784. PMID 33007562 DOI: 10.1016/j.bmc.2020.115784   
2020 Huo PC, Guan XQ, Liu P, Song YQ, Sun MR, He RJ, Zou LW, Xue LJ, Shi JH, Zhang N, Liu ZG, Ge GB. Design, synthesis and biological evaluation of indanone-chalcone hybrids as potent and selective hCES2A inhibitors. European Journal of Medicinal Chemistry. 209: 112856. PMID 33007602 DOI: 10.1016/j.ejmech.2020.112856   
2020 Chen H, Zhang X, Zhang X, Fan Z, Liu W, Lei Y, Zhu C, Ma B. Dihydrobenzoxazinone derivatives as aldose reductase inhibitors with antioxidant activity. Bioorganic & Medicinal Chemistry. 28: 115699. PMID 33069078 DOI: 10.1016/j.bmc.2020.115699   
2020 Hassan HA, Abdelmohsen UR, Aly OM, Desoukey SY, Mohamed KM, Kamel MS. Potential of metabolites against SARS-CoV-2 main protease supported by docking studies. Natural Product Research. 1-5. PMID 33121282 DOI: 10.1080/14786419.2020.1839452   
2020 Zhu M, Li W, Zhao T, Chen Y, Li T, Wei S, Guo M, Zhai X. Fragment-based modification of 2,4-diarylaminopyrimidine derivatives as ALK and ROS1 dual inhibitors to overcome secondary mutants. Bioorganic & Medicinal Chemistry. 28: 115719. PMID 33069075 DOI: 10.1016/j.bmc.2020.115719   
2020 Veeravarapu H, Tirumalasetty M, Priya Kurati S, Wunnava U, Krishna Kumar Muthyala M. Design, synthesis, antimycobacterial activity and molecular docking studies of novel 3- (N-substituted glycinamido) benzoic acid analogues as anti tubercular agents. Bioorganic & Medicinal Chemistry Letters. 127603. PMID 33039564 DOI: 10.1016/j.bmcl.2020.127603   
2020 Christensen EM, Bogner AN, Vandekeere A, Tam GS, Patel SM, Becker DF, Fendt SM, Tanner JJ. Screening for Proline Analog Inhibitors of the Proline Cycle Enzyme PYCR1. The Journal of Biological Chemistry. PMID 33109600 DOI: 10.1074/jbc.RA120.016106   
2020 Li JX, Lei XX, Tan YH, Liu YH, Yang B, Li YQ. Two new bioactive polyphenols from the soft coral-derived fungus sp. SCSIO 041201. Natural Product Research. 1-8. PMID 33107331 DOI: 10.1080/14786419.2020.1836632   
2020 Crocetti L, Giovannoni MP, Cantini N, Guerrini G, Vergelli C, Schepetkin IA, Khlebnikov AI, Quinn MT. Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors. Frontiers in Chemistry. 8: 795. PMID 33033716 DOI: 10.3389/fchem.2020.00795   
2020 Yan L, Banuelos CA, Mawji NR, Patrick BO, Sadar MD, Andersen RJ. Structure-Activity Relationships for the Marine Natural Product Sintokamides: Androgen Receptor N-Terminus Antagonists of Interest for Treatment of Metastatic Castration-Resistant Prostate Cancer. Journal of Natural Products. PMID 33124806 DOI: 10.1021/acs.jnatprod.0c00921   
2020 Gu X, Pisoni LA, Wang Y, Song D, Sykes MJ, Qin Y, Semple SJ, Polyak SW, Venter H, Ma S. Design and synthesis of novel 4-substituted quinazoline-2-carboxamide derivatives targeting AcrB to reverse the bacterial multidrug resistance. Bioorganic Chemistry. 105: 104394. PMID 33120321 DOI: 10.1016/j.bioorg.2020.104394   
2020 Akinpelu OI, Lawal MM, Kumalo HM, Mhlongo NN. Computational studies of the properties and activities of selected trisubstituted benzimidazoles as potential antitubercular drugs inhibiting MTB-FtsZ polymerization. Journal of Biomolecular Structure & Dynamics. 1-13. PMID 33021149 DOI: 10.1080/07391102.2020.1830176   
2020 Uddin N, Ali N, Uddin Z, Nazir N, Zahoor M, Rashid U, Ullah R, Alqahtani AS, Alqahtani AM, Nasr FA, Liu M, Nisar M. Evaluation of Cholinesterase Inhibitory Potential of Different Genotypes of , Their HPLC-UV, and Molecular Docking Analysis. Molecules (Basel, Switzerland). 25. PMID 33137939 DOI: 10.3390/molecules25215011   
2020 Naz F, Kanwal, Latif M, Salar U, Khan KM, Al-Rashida M, Ali I, Ali B, Taha M, Perveen S. 4-Oxycoumarinyl linked acetohydrazide Schiff bases as potent urease inhibitors. Bioorganic Chemistry. 105: 104365. PMID 33091669 DOI: 10.1016/j.bioorg.2020.104365   
2020 Wu XW, Wang Q, Li Q, Cui YM, Pu YK, Shi QQ, Bi DW, Zhang JJ, Zhang RH, Li XL, Zhang XJ, Xiao WL. Rubellawus A-D, Four New Diterpenoids Isolated from Callicarpa rubella and their Anti-NLRP3 Inflammasome Effects. Chemistry & Biodiversity. PMID 33135326 DOI: 10.1002/cbdv.202000798   
2020 Adeowo FY, Ejalonibu MA, Elrashedy AA, Lawal MM, Kumalo HM. Multi-target approach for Alzheimer's disease treatment: computational biomolecular modeling of cholinesterase enzymes with a novel 4--phenylaminoquinoline derivative reveal promising potentials. Journal of Biomolecular Structure & Dynamics. 1-17. PMID 33030113 DOI: 10.1080/07391102.2020.1826129   
2020 Zhang RB, Yu SY, Liang L, Ismail I, Wang DW, Li YH, Xu H, Wen X, Xi Z. Design, Synthesis, and Molecular Mechanism Studies of -Phenylisoxazoline-thiadiazolo[3,4-]pyridazine Hybrids as Protoporphyrinogen IX Oxidase Inhibitors. Journal of Agricultural and Food Chemistry. PMID 33155804 DOI: 10.1021/acs.jafc.0c05955   
2020 Anwar F, Saleem U, Ahmad B, Ashraf M, Rehman AU, Froeyen M, Kee LY, Abdullah I, Mirza MU, Ahmad S. New naphthalene derivative for cost-effective AChE inhibitors for Alzheimer's treatment: In silico identification, in vitro and in vivo validation. Computational Biology and Chemistry. 89: 107378. PMID 33002716 DOI: 10.1016/j.compbiolchem.2020.107378   
2020 Hervin V, Arora R, Rani J, Ramchandran S, Bajpai U, Agrofoglio LA, Roy V. Design and Synthesis of Various 5'-Deoxy-5'-(4-Substituted-1,2,3-Triazol-1-yl)-Uridine Analogues as Inhibitors of Mur Ligases. Molecules (Basel, Switzerland). 25. PMID 33114668 DOI: 10.3390/molecules25214953   
2020 Poletto J, da Silva MJV, Jacomini AP, Bidóia DL, Volpato H, Nakamura CV, Rosa FA. Antiparasitic activities of novel pyrimidine N-acylhydrazone hybrids. Drug Development Research. PMID 32996619 DOI: 10.1002/ddr.21745   
2020 Robin SKD, Ansari M, Uppugunduri CRS. Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases. Journal of Visualized Experiments : Jove. PMID 33104076 DOI: 10.3791/61347   
2020 Lin P, Zeng JC, Chen JG, Nie XL, Yuan E, Wang XQ, Peng DY, Yin ZP. Synthesis, inhibitory activity, kinetic study and molecular docking of novel -alkyl-deoxynojirimycin derivatives as potential α-glucosidase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 35: 1879-1890. PMID 33003963 DOI: 10.1080/14756366.2020.1826941   
2020 Lin P, Zeng JC, Chen JG, Nie XL, Yuan E, Wang XQ, Peng DY, Yin ZP. Synthesis, inhibitory activity, kinetic study and molecular docking of novel -alkyl-deoxynojirimycin derivatives as potential α-glucosidase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 35: 1879-1890. PMID 33003963 DOI: 10.1080/14756366.2020.1826941   
2020 Zhang Q, Yang W, Liu J, Liu H, Lv Z, Zhang C, Chen D, Jiao Z. Identification of Six Flavonoids as Novel Cellular Antioxidants and Their Structure-Activity Relationship. Oxidative Medicine and Cellular Longevity. 2020: 4150897. PMID 33014269 DOI: 10.1155/2020/4150897   
2020 Song J, Malwal SR, Baig N, Schurig-Briccio LA, Gao Z, Vaidya GS, Yang K, Abutaleb NS, Seleem MN, Gennis RB, Pogorelov TV, Oldfield E, Feng X. Discovery of Prenyltransferase Inhibitors with and Antibacterial Activity. Acs Infectious Diseases. PMID 33085463 DOI: 10.1021/acsinfecdis.0c00472   
2020 Coelho C, Gallo G, Campos CB, Hardy L, Würtele M. Biochemical screening for SARS-CoV-2 main protease inhibitors. Plos One. 15: e0240079. PMID 33022015 DOI: 10.1371/journal.pone.0240079   
2020 Centko RM, Carlile GW, Barne I, Patrick BO, Blagojevic P, Thomas DY, Andersen RJ. Combination of Selective PARP3 and PARP16 Inhibitory Analogues of Latonduine A Corrects F508del-CFTR Trafficking. Acs Omega. 5: 25593-25604. PMID 33073085 DOI: 10.1021/acsomega.0c02467