Marc K. Hellerstein - Publications

Affiliations: 
University of California, Berkeley, Berkeley, CA 
Area:
Cell Biology, Nutrition, Oncology, Analytical Chemistry
Website:
https://vcresearch.berkeley.edu/faculty/marc-hellerstein

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Esler WP, Tesz GJ, Hellerstein MK, Beysen C, Sivamani R, Turner SM, Watkins SM, Amor PA, Carvajal-Gonzalez S, Geoly FJ, Biddle KE, Purkal JJ, Fitch M, Buckeridge C, Silvia AM, et al. Human sebum requires de novo lipogenesis, which is increased in acne vulgaris and suppressed by acetyl-CoA carboxylase inhibition. Science Translational Medicine. 11. PMID 31092695 DOI: 10.1126/scitranslmed.aau8465  0.52
2019 Krois CR, Vuckovic MG, Huang P, Zaversnik C, Liu CS, Gibson CE, Wheeler MR, Obrochta KM, Min JH, Herber CB, Thompson AC, Shah ID, Gordon SP, Hellerstein MK, Napoli JL. RDH1 suppresses adiposity by promoting brown adipose adaptation to fasting and re-feeding. Cellular and Molecular Life Sciences : Cmls. PMID 30788515 DOI: 10.1007/s00018-019-03046-z  0.84
2018 Loomba R, Decaris M, Li KW, Shankaran M, Mohammed H, Matthews M, Richards LM, Nguyen P, Rizo E, Andrews B, Soto R, Angel T, Suri V, Kitrinos KM, Barnes D, ... ... Hellerstein MK, et al. Discovery of half-life of circulating HBsAg in patients with chronic hepatitis B infection using heavy water labeling. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 30590481 DOI: 10.1093/cid/ciy1100  0.32
2018 Shankaran M, Czerwieniec G, Fessler C, Wong PA, Killion S, Turner SM, Hellerstein MK, Evans WJ. Dilution of oral D -Creatine to measure creatine pool size and estimate skeletal muscle mass: development of a correction algorithm. Journal of Cachexia, Sarcopenia and Muscle. PMID 29663711 DOI: 10.1002/jcsm.12278  0.52
2018 Beysen C, Ruddy M, Stoch A, Mixson LA, Rosko K, Riiff T, Turner SM, Hellerstein MK, Murphy EJ. Dose-dependent quantitative effects of acute fructose administration on hepatic de novo lipogenesis in healthy humans. American Journal of Physiology. Endocrinology and Metabolism. PMID 29558206 DOI: 10.1152/ajpendo.00470.2017  0.52
2017 Burger JA, Li KW, Keating MJ, Sivina M, Amer AM, Garg N, Ferrajoli A, Huang X, Kantarjian H, Wierda WG, O'Brien S, Hellerstein MK, Turner SM, Emson CL, Chen SS, et al. Leukemia cell proliferation and death in chronic lymphocytic leukemia patients on therapy with the BTK inhibitor ibrutinib. Jci Insight. 2: e89904. PMID 28138560 DOI: 10.1172/jci.insight.89904  0.52
2016 Decaris ML, Li KW, Emson CL, Gatmaitan M, Liu S, Wang Y, Nyangau E, Colangelo M, Angel TE, Beysen C, Cui J, Hernandez C, Lazaro L, Brenner DA, Turner SM, ... Hellerstein MK, et al. Identifying NAFLD Patients with Active Fibrosis by Measuring Extracellular Matrix Remodeling Rates in Tissue and Blood. Hepatology (Baltimore, Md.). PMID 27706836 DOI: 10.1002/hep.28860  0.52
2016 Pierce AA, Duwaerts CC, Soon RK, Siao K, Grenert JP, Fitch M, Hellerstein MK, Beysen C, Turner SM, Maher JJ. Isocaloric manipulation of macronutrients within a high-carbohydrate/moderate-fat diet induces unique effects on hepatic lipogenesis, steatosis and liver injury. The Journal of Nutritional Biochemistry. 29: 12-20. PMID 26895660 DOI: 10.1016/j.jnutbio.2015.10.020  0.56
2015 Shankaran M, Shearer TW, Stimpson SA, Turner SM, King C, Wong PA, Shen Y, Turnbull PS, Kramer F, Clifton L, Russell AJ, Hellerstein MK, Evans WJ. Proteome-wide muscle protein fractional synthesis rates predict muscle mass gain in response to a selective androgen receptor modulator in rats. American Journal of Physiology. Endocrinology and Metabolism. ajpendo.00257.2015. PMID 26714847 DOI: 10.1152/ajpendo.00257.2015  0.52
2015 Shankaran M, King CL, Angel TE, Holmes WE, Li KW, Colangelo M, Price JC, Turner SM, Bell C, Hamilton KL, Miller BF, Hellerstein MK. Circulating protein synthesis rates reveal skeletal muscle proteome dynamics. The Journal of Clinical Investigation. PMID 26657858 DOI: 10.1172/JCI79639  0.56
2015 Bluestone JA, Buckner JH, Fitch M, Gitelman SE, Gupta S, Hellerstein MK, Herold KC, Lares A, Lee MR, Li K, Liu W, Long SA, Masiello LM, Nguyen V, Putnam AL, et al. Type 1 diabetes immunotherapy using polyclonal regulatory T cells. Science Translational Medicine. 7: 315ra189. PMID 26606968 DOI: 10.1126/scitranslmed.aad4134  0.56
2015 Thompson AC, Bruss MD, Price JC, Khambatta CF, Holmes WE, Colangelo M, Dalidd M, Roberts LS, Astle CM, Harrison DE, Hellerstein MK. Reduced in vivo hepatic proteome replacement rates but not cell proliferation rates predict maximum lifespan extension in mice. Aging Cell. PMID 26541492 DOI: 10.1111/acel.12414  0.56
2015 Ladell K, Hazenberg MD, Fitch M, Emson C, McEvoy-Hein Asgarian BK, Mold JE, Miller C, Busch R, Price DA, Hellerstein MK, McCune JM. Continuous Antigenic Stimulation of DO11.10 TCR Transgenic Mice in the Presence or Absence of IL-1β: Possible Implications for Mechanisms of T Cell Depletion in HIV Disease. Journal of Immunology (Baltimore, Md. : 1950). PMID 26416271 DOI: 10.4049/jimmunol.1500799  0.56
2015 Johnson ML, Lalia AZ, Dasari S, Pallauf M, Fitch M, Hellerstein MK, Lanza IR. Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice. Aging Cell. PMID 26010060 DOI: 10.1111/acel.12352  0.56
2015 Decaris ML, Emson CL, Li K, Gatmaitan M, Luo F, Cattin J, Nakamura C, Holmes WE, Angel TE, Peters MG, Turner SM, Hellerstein MK. Turnover rates of hepatic collagen and circulating collagen-associated proteins in humans with chronic liver disease. Plos One. 10: e0123311. PMID 25909381 DOI: 10.1371/journal.pone.0123311  0.56
2015 Charles-Schoeman C, Fleischmann R, Davignon J, Schwartz H, Turner SM, Beysen C, Milad M, Hellerstein MK, Luo Z, Kaplan IV, Riese R, Zuckerman A, McInnes IB. Potential mechanisms leading to the abnormal lipid profile in patients with rheumatoid arthritis versus healthy volunteers and reversal by tofacitinib. Arthritis & Rheumatology (Hoboken, N.J.). 67: 616-25. PMID 25470338 DOI: 10.1002/art.38974  0.56
2015 Allister CA, Liu LF, Lamendola CA, Craig CM, Cushman SW, Hellerstein MK, McLaughlin TL. In vivo 2H2O administration reveals impaired triglyceride storage in adipose tissue of insulin-resistant humans. Journal of Lipid Research. 56: 435-9. PMID 25418322 DOI: 10.1194/jlr.M052860  0.56
2014 Thompson AC, Bruss MD, Nag N, Kharitonenkov A, Adams AC, Hellerstein MK. Fibroblast growth factor 21 is not required for the reductions in circulating insulin-like growth factor-1 or global cell proliferation rates in response to moderate calorie restriction in adult mice. Plos One. 9: e111418. PMID 25369265 DOI: 10.1371/journal.pone.0111418  0.56
2014 Zhang T, Price JC, Nouri-Nigjeh E, Li J, Hellerstein MK, Qu J, Ghaemmaghami S. Kinetics of precursor labeling in stable isotope labeling in cell cultures (SILAC) experiments. Analytical Chemistry. 86: 11334-41. PMID 25301408 DOI: 10.1021/ac503067a  0.56
2014 Bayes SK, Hellerstein MK, Fitch M, Mills NJ, Welter SC. You are what you eat: fatty acid profiles as a method to track the habitat movement of an insect. Oecologia. 175: 1073-80. PMID 24880704 DOI: 10.1007/s00442-014-2976-9  0.56
2014 Clark RV, Walker AC, O'Connor-Semmes RL, Leonard MS, Miller RR, Stimpson SA, Turner SM, Ravussin E, Cefalu WT, Hellerstein MK, Evans WJ. Total body skeletal muscle mass: estimation by creatine (methyl-d3) dilution in humans. Journal of Applied Physiology (Bethesda, Md. : 1985). 116: 1605-13. PMID 24764133 DOI: 10.1152/japplphysiol.00045.2014  0.56
2014 Decaris ML, Gatmaitan M, FlorCruz S, Luo F, Li K, Holmes WE, Hellerstein MK, Turner SM, Emson CL. Proteomic analysis of altered extracellular matrix turnover in bleomycin-induced pulmonary fibrosis. Molecular & Cellular Proteomics : McP. 13: 1741-52. PMID 24741116 DOI: 10.1074/mcp.M113.037267  0.56
2014 Scalzo RL, Peltonen GL, Binns SE, Shankaran M, Giordano GR, Hartley DA, Klochak AL, Lonac MC, Paris HL, Szallar SE, Wood LM, Peelor FF, Holmes WE, Hellerstein MK, Bell C, et al. Greater muscle protein synthesis and mitochondrial biogenesis in males compared with females during sprint interval training. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2705-14. PMID 24599968 DOI: 10.1096/fj.13-246595  0.56
2013 Veerapathran A, Pidala J, Beato F, Betts B, Kim J, Turner JG, Hellerstein MK, Yu XZ, Janssen W, Anasetti C. Human regulatory T cells against minor histocompatibility antigens: ex vivo expansion for prevention of graft-versus-host disease. Blood. 122: 2251-61. PMID 23908471 DOI: 10.1182/blood-2013-03-492397  0.56
2013 Stimpson SA, Leonard MS, Clifton LG, Poole JC, Turner SM, Shearer TW, Remlinger KS, Clark RV, Hellerstein MK, Evans WJ. Longitudinal changes in total body creatine pool size and skeletal muscle mass using the D3-creatine dilution method. Journal of Cachexia, Sarcopenia and Muscle. PMID 23797207 DOI: 10.1007/s13539-013-0110-1  0.56
2013 Emson CL, Fitzmaurice S, Lindwall G, Li KW, Hellerstein MK, Maibach HI, Liao W, Turner SM. A pilot study demonstrating a non-invasive method for the measurement of protein turnover in skin disorders: application to psoriasis. Clinical and Translational Medicine. 2: 12. PMID 23773261 DOI: 10.1186/2001-1326-2-12  0.52
2013 Holleboom AG, Jakulj L, Franssen R, Decaris J, Vergeer M, Koetsveld J, Luchoomun J, Glass A, Hellerstein MK, Kastelein JJ, Hovingh GK, Kuivenhoven JA, Groen AK, Turner SM, Stroes ES. In vivo tissue cholesterol efflux is reduced in carriers of a mutation in APOA1. Journal of Lipid Research. 54: 1964-71. PMID 23650622 DOI: 10.1194/jlr.P028449  0.56
2013 Liew CW, Boucher J, Cheong JK, Vernochet C, Koh HJ, Mallol C, Townsend K, Langin D, Kawamori D, Hu J, Tseng YH, Hellerstein MK, Farmer SR, Goodyear L, Doria A, et al. Ablation of TRIP-Br2, a regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance. Nature Medicine. 19: 217-26. PMID 23291629 DOI: 10.1038/nm.3056  0.56
2013 Harris C, Roohk DJ, Fitch M, Boudignon BM, Halloran BP, Hellerstein MK. Large increases in adipose triacylglycerol flux in Cushingoid CRH-Tg mice are explained by futile cycling. American Journal of Physiology. Endocrinology and Metabolism. 304: E282-93. PMID 23211515 DOI: 10.1152/ajpendo.00154.2012  0.84
2013 Miller BF, Robinson MM, Reuland DJ, Drake JC, Peelor FF, Bruss MD, Hellerstein MK, Hamilton KL. Calorie restriction does not increase short-term or long-term protein synthesis. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 68: 530-8. PMID 23105041 DOI: 10.1093/gerona/gls219  0.56
2012 Price JC, Khambatta CF, Li KW, Bruss MD, Shankaran M, Dalidd M, Floreani NA, Roberts LS, Turner SM, Holmes WE, Hellerstein MK. The effect of long term calorie restriction on in vivo hepatic proteostatis: a novel combination of dynamic and quantitative proteomics. Molecular & Cellular Proteomics : McP. 11: 1801-14. PMID 22984287 DOI: 10.1074/mcp.M112.021204  0.56
2012 Fanara P, Wong PY, Husted KH, Liu S, Liu VM, Kohlstaedt LA, Riiff T, Protasio JC, Boban D, Killion S, Killian M, Epling L, Sinclair E, Peterson J, Price RW, ... ... Hellerstein MK, et al. Cerebrospinal fluid-based kinetic biomarkers of axonal transport in monitoring neurodegeneration. The Journal of Clinical Investigation. 122: 3159-69. PMID 22922254 DOI: 10.1172/JCI64575  0.56
2012 Stimpson SA, Turner SM, Clifton LG, Poole JC, Mohammed HA, Shearer TW, Waitt GM, Hagerty LL, Remlinger KS, Hellerstein MK, Evans WJ. Total-body creatine pool size and skeletal muscle mass determination by creatine-(methyl-D3) dilution in rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 112: 1940-8. PMID 22422801 DOI: 10.1152/japplphysiol.00122.2012  0.56
2012 Tchoukalova YD, Fitch M, Rogers PM, Covington JD, Henagan TM, Ye J, Hellerstein MK, Ravussin E. In vivo adipogenesis in rats measured by cell kinetics in adipocytes and plastic-adherent stroma-vascular cells in response to high-fat diet and thiazolidinedione. Diabetes. 61: 137-44. PMID 22124466 DOI: 10.2337/db10-1768  0.56
2012 Price JC, Holmes WE, Li KW, Floreani NA, Neese RA, Turner SM, Hellerstein MK. Measurement of human plasma proteome dynamics with (2)H(2)O and liquid chromatography tandem mass spectrometry. Analytical Biochemistry. 420: 73-83. PMID 21964502 DOI: 10.1016/j.ab.2011.09.007  0.56
2011 Calissano C, Damle RN, Marsilio S, Yan XJ, Yancopoulos S, Hayes G, Emson C, Murphy EJ, Hellerstein MK, Sison C, Kaufman MS, Kolitz JE, Allen SL, Rai KR, Ivanovic I, et al. Intraclonal complexity in chronic lymphocytic leukemia: fractions enriched in recently born/divided and older/quiescent cells. Molecular Medicine (Cambridge, Mass.). 17: 1374-82. PMID 21968788 DOI: 10.2119/molmed.2011.00360  0.56
2011 Ahmadian M, Abbott MJ, Tang T, Hudak CS, Kim Y, Bruss M, Hellerstein MK, Lee HY, Samuel VT, Shulman GI, Wang Y, Duncan RE, Kang C, Sul HS. Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype. Cell Metabolism. 13: 739-48. PMID 21641555 DOI: 10.1016/j.cmet.2011.05.002  0.56
2011 Li KW, Turner SM, Emson CL, Hellerstein MK, Dale DC. Deuterium and neutrophil kinetics. Blood. 117: 6052-3; author reply. PMID 21636721 DOI: 10.1182/blood-2010-12-322271  0.56
2011 Robinson MM, Turner SM, Hellerstein MK, Hamilton KL, Miller BF. Long-term synthesis rates of skeletal muscle DNA and protein are higher during aerobic training in older humans than in sedentary young subjects but are not altered by protein supplementation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 3240-9. PMID 21613572 DOI: 10.1096/fj.11-186437  0.56
2011 Bruss MD, Thompson AC, Aggarwal I, Khambatta CF, Hellerstein MK. The effects of physiological adaptations to calorie restriction on global cell proliferation rates. American Journal of Physiology. Endocrinology and Metabolism. 300: E735-45. PMID 21285400 DOI: 10.1152/ajpendo.00661.2010  0.84
2011 Hudgins LC, Parker TS, Levine DM, Hellerstein MK. A dual sugar challenge test for lipogenic sensitivity to dietary fructose. The Journal of Clinical Endocrinology and Metabolism. 96: 861-8. PMID 21252253 DOI: 10.1210/jc.2010-2007  0.56
2010 Roohk DJ, Varady KA, Turner SM, Emson CL, Gelling RW, Shankaran M, Lindwall G, Shipp LE, Scanlan TS, Wang JC, Hellerstein MK. Differential in vivo effects on target pathways of a novel arylpyrazole glucocorticoid receptor modulator compared with prednisolone. The Journal of Pharmacology and Experimental Therapeutics. 333: 281-9. PMID 20065017 DOI: 10.1124/jpet.109.162487  0.56
2010 Bruss MD, Khambatta CF, Ruby MA, Aggarwal I, Hellerstein MK. Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates. American Journal of Physiology. Endocrinology and Metabolism. 298: E108-16. PMID 19887594 DOI: 10.1152/ajpendo.00524.2009  0.84
2010 Varady KA, Allister CA, Roohk DJ, Hellerstein MK. Improvements in body fat distribution and circulating adiponectin by alternate-day fasting versus calorie restriction. The Journal of Nutritional Biochemistry. 21: 188-95. PMID 19195863 DOI: 10.1016/j.jnutbio.2008.11.001  0.84
2009 Stanhope KL, Schwarz JM, Keim NL, Griffen SC, Bremer AA, Graham JL, Hatcher B, Cox CL, Dyachenko A, Zhang W, McGahan JP, Seibert A, Krauss RM, Chiu S, Schaefer EJ, ... ... Hellerstein MK, et al. Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. The Journal of Clinical Investigation. 119: 1322-34. PMID 19381015 DOI: 10.1172/JCI37385  0.56
2009 Varady KA, Hudak CS, Hellerstein MK. Modified alternate-day fasting and cardioprotection: relation to adipose tissue dynamics and dietary fat intake. Metabolism: Clinical and Experimental. 58: 803-11. PMID 19375762 DOI: 10.1016/j.metabol.2009.01.018  0.56
2009 Jaworski K, Ahmadian M, Duncan RE, Sarkadi-Nagy E, Varady KA, Hellerstein MK, Lee HY, Samuel VT, Shulman GI, Kim KH, de Val S, Kang C, Sul HS. AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency. Nature Medicine. 15: 159-68. PMID 19136964 DOI: 10.1038/nm.1904  0.56
2009 Ahmadian M, Duncan RE, Varady KA, Frasson D, Hellerstein MK, Birkenfeld AL, Samuel VT, Shulman GI, Wang Y, Kang C, Sul HS. Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity. Diabetes. 58: 855-66. PMID 19136649 DOI: 10.2337/db08-1644  0.56
2009 Varady KA, Roohk DJ, Bruss M, Hellerstein MK. Alternate-day fasting reduces global cell proliferation rates independently of dietary fat content in mice. Nutrition (Burbank, Los Angeles County, Calif.). 25: 486-91. PMID 19084375 DOI: 10.1016/j.nut.2008.10.017  0.84
2008 Kim J, Choi YL, Vallentin A, Hunrichs BS, Hellerstein MK, Peehl DM, Mochly-Rosen D. Centrosomal PKCbetaII and pericentrin are critical for human prostate cancer growth and angiogenesis. Cancer Research. 68: 6831-9. PMID 18701509 DOI: 10.1158/0008-5472.CAN-07-6195  0.56
2008 Beysen C, Murphy EJ, Nagaraja H, Decaris M, Riiff T, Fong A, Hellerstein MK, Boyle PJ. A pilot study of the effects of pioglitazone and rosiglitazone on de novo lipogenesis in type 2 diabetes. Journal of Lipid Research. 49: 2657-63. PMID 18641372 DOI: 10.1194/jlr.M800165-JLR200  0.56
2008 Busch R, Siah IM, Gee TA, Hellerstein MK. Heavy water labeling of DNA for measurement of cell proliferation and recruitment during primary murine lymph node responses against model antigens. Journal of Immunological Methods. 337: 24-34. PMID 18590913 DOI: 10.1016/j.jim.2008.05.014  0.56
2008 Ladell K, Hellerstein MK, Cesar D, Busch R, Boban D, McCune JM. Central memory CD8+ T cells appear to have a shorter lifespan and reduced abundance as a function of HIV disease progression. Journal of Immunology (Baltimore, Md. : 1950). 180: 7907-18. PMID 18523254  0.56
2008 Varady KA, Hellerstein MK. Do calorie restriction or alternate-day fasting regimens modulate adipose tissue physiology in a way that reduces chronic disease risk? Nutrition Reviews. 66: 333-42. PMID 18522622 DOI: 10.1111/j.1753-4887.2008.00041.x  0.84
2008 Varady KA, Roohk DJ, McEvoy-Hein BK, Gaylinn BD, Thorner MO, Hellerstein MK. Modified alternate-day fasting regimens reduce cell proliferation rates to a similar extent as daily calorie restriction in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2090-6. PMID 18184721 DOI: 10.1096/fj.07-098178  0.84
2008 Hudgins LC, Baday A, Hellerstein MK, Parker TS, Levine DM, Seidman CE, Neese RA, Tremaroli JD, Hirsch J. The effect of dietary carbohydrate on genes for fatty acid synthase and inflammatory cytokines in adipose tissues from lean and obese subjects. The Journal of Nutritional Biochemistry. 19: 237-45. PMID 17618104 DOI: 10.1016/j.jnutbio.2007.02.013  0.56
2007 Voogt JN, Awada M, Murphy EJ, Hayes GM, Busch R, Hellerstein MK. Measurement of very low rates of cell proliferation by heavy water labeling of DNA and gas chromatography/pyrolysis/isotope ratio-mass spectrometric analysis. Nature Protocols. 2: 3058-62. PMID 18079704 DOI: 10.1038/nprot.2007.421  0.56
2007 Busch R, Neese RA, Awada M, Hayes GM, Hellerstein MK. Measurement of cell proliferation by heavy water labeling. Nature Protocols. 2: 3045-57. PMID 18079703 DOI: 10.1038/nprot.2007.420  0.56
2007 Varady KA, Hellerstein MK. Alternate-day fasting and chronic disease prevention: a review of human and animal trials. The American Journal of Clinical Nutrition. 86: 7-13. PMID 17616757  0.84
2007 Varady KA, Roohk DJ, Loe YC, McEvoy-Hein BK, Hellerstein MK. Effects of modified alternate-day fasting regimens on adipocyte size, triglyceride metabolism, and plasma adiponectin levels in mice. Journal of Lipid Research. 48: 2212-9. PMID 17607017 DOI: 10.1194/jlr.M700223-JLR200  0.84
2007 Kim SJ, Hellerstein MK. Pharmacological doses of dietary curcumin increase colon epithelial cell proliferation in vivo in rats. Phytotherapy Research : Ptr. 21: 995-8. PMID 17582595 DOI: 10.1002/ptr.2053  0.8
2007 Shankaran M, Marino ME, Busch R, Keim C, King C, Lee J, Killion S, Awada M, Hellerstein MK. Measurement of brain microglial proliferation rates in vivo in response to neuroinflammatory stimuli: application to drug discovery. Journal of Neuroscience Research. 85: 2374-84. PMID 17551981 DOI: 10.1002/jnr.21389  0.56
2007 Varady KA, Roohk DJ, Hellerstein MK. Dose effects of modified alternate-day fasting regimens on in vivo cell proliferation and plasma insulin-like growth factor-1 in mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 103: 547-51. PMID 17495119 DOI: 10.1152/japplphysiol.00209.2007  0.84
2007 Gardner JL, Turner SM, Bautista A, Lindwall G, Awada M, Hellerstein MK. Measurement of liver collagen synthesis by heavy water labeling: effects of profibrotic toxicants and antifibrotic interventions. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G1695-705. PMID 17347453 DOI: 10.1152/ajpgi.00209.2006  0.56
2007 Beysen C, Murphy EJ, McLaughlin T, Riiff T, Lamendola C, Turner HC, Awada M, Turner SM, Reaven G, Hellerstein MK. Whole-body glycolysis measured by the deuterated-glucose disposal test correlates highly with insulin resistance in vivo. Diabetes Care. 30: 1143-9. PMID 17259480 DOI: 10.2337/dc06-1809  0.52
2007 Turner SM, Roy S, Sul HS, Neese RA, Murphy EJ, Samandi W, Roohk DJ, Hellerstein MK. Dissociation between adipose tissue fluxes and lipogenic gene expression in ob/ob mice. American Journal of Physiology. Endocrinology and Metabolism. 292: E1101-9. PMID 17164440 DOI: 10.1152/ajpendo.00309.2005  0.56
2006 Shankaran M, King C, Lee J, Busch R, Wolff M, Hellerstein MK. Discovery of novel hippocampal neurogenic agents by using an in vivo stable isotope labeling technique. The Journal of Pharmacology and Experimental Therapeutics. 319: 1172-81. PMID 16973885 DOI: 10.1124/jpet.106.110510  0.56
2006 Vedala A, Wang W, Neese RA, Christiansen MP, Hellerstein MK. Delayed secretory pathway contributions to VLDL-triglycerides from plasma NEFA, diet, and de novo lipogenesis in humans. Journal of Lipid Research. 47: 2562-74. PMID 16929033 DOI: 10.1194/jlr.M600200-JLR200  0.56
2006 Chu A, Ordonez ET, Hellerstein MK. Measurement of mouse vascular smooth muscle and atheroma cell proliferation by 2H2O incorporation into DNA. American Journal of Physiology. Cell Physiology. 291: C1014-21. PMID 16774990 DOI: 10.1152/ajpcell.00191.2006  0.56
2006 Parks EJ, Hellerstein MK. Thematic review series: patient-oriented research. Recent advances in liver triacylglycerol and fatty acid metabolism using stable isotope labeling techniques. Journal of Lipid Research. 47: 1651-60. PMID 16741290 DOI: 10.1194/jlr.R600018-JLR200  0.92
2006 Busch R, Kim YK, Neese RA, Schade-Serin V, Collins M, Awada M, Gardner JL, Beysen C, Marino ME, Misell LM, Hellerstein MK. Measurement of protein turnover rates by heavy water labeling of nonessential amino acids Biochimica Et Biophysica Acta - General Subjects. 1760: 730-744. PMID 16567052 DOI: 10.1016/j.bbagen.2005.12.023  0.56
2006 Lindwall G, Hsieh EA, Misell LM, Chai CM, Turner SM, Hellerstein MK. Heavy water labeling of keratin as a non-invasive biomarker of skin turnover in vivo in rodents and humans. The Journal of Investigative Dermatology. 126: 841-8. PMID 16470175 DOI: 10.1038/sj.jid.5700189  0.64
2006 Misell LM, Holochwost D, Boban D, Santi N, Shefi S, Hellerstein MK, Turek PJ. A stable isotope-mass spectrometric method for measuring human spermatogenesis kinetics in vivo. The Journal of Urology. 175: 242-6; discussion 24. PMID 16406920 DOI: 10.1016/S0022-5347(05)00053-4  0.52
2005 Chen JL, Peacock E, Samady W, Turner SM, Neese RA, Hellerstein MK, Murphy EJ. Physiologic and pharmacologic factors influencing glyceroneogenic contribution to triacylglyceride glycerol measured by mass isotopomer distribution analysis. The Journal of Biological Chemistry. 280: 25396-402. PMID 15888453 DOI: 10.1074/jbc.M413948200  0.56
2005 Kim SJ, Turner S, Killion S, Hellerstein MK. In vivo measurement of DNA synthesis rates of colon epithelial cells in carcinogenesis. Biochemical and Biophysical Research Communications. 331: 203-9. PMID 15845379 DOI: 10.1016/j.bbrc.2005.02.195  0.8
2005 Misell LM, Hwang ES, Au A, Esserman L, Hellerstein MK. Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans. Breast Cancer Research and Treatment. 89: 257-64. PMID 15754124 DOI: 10.1007/s10549-004-2228-5  0.52
2005 Turner SM, Hellerstein MK. Emerging applications of kinetic biomarkers in preclinical and clinical drug development. Current Opinion in Drug Discovery & Development. 8: 115-26. PMID 15679179  0.52
2005 Hsieh EA, Chai CM, Hellerstein MK. Effects of caloric restriction on cell proliferation in several tissues in mice: role of intermittent feeding. American Journal of Physiology. Endocrinology and Metabolism. 288: E965-72. PMID 15613681 DOI: 10.1152/ajpendo.00368.2004  0.64
2004 Hsieh EA, Chai CM, de Lumen BO, Neese RA, Hellerstein MK. Dynamics of keratinocytes in vivo using HO labeling: a sensitive marker of epidermal proliferation state. The Journal of Investigative Dermatology. 123: 530-6. PMID 15304093 DOI: 10.1111/j.0022-202X.2004.23303.x  0.56
2004 Busch R, Cesar D, Higuera-Alhino D, Gee T, Hellerstein MK, McCune JM. Isolation of peripheral blood CD4(+) T cells using RosetteSep and MACS for studies of DNA turnover by deuterium labeling. Journal of Immunological Methods. 286: 97-109. PMID 15087225 DOI: 10.1016/j.jim.2003.12.012  0.56
2004 Kim SJ, Cheung S, Hellerstein MK. Isolation of nuclei from label-retaining cells and measurement of their turnover rates in rat colon. American Journal of Physiology. Cell Physiology. 286: C1464-73. PMID 14960413 DOI: 10.1152/ajpcell.00139.2003  0.8
2003 Hellerstein MK, Hoh RA, Hanley MB, Cesar D, Lee D, Neese RA, McCune JM. Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection. The Journal of Clinical Investigation. 112: 956-66. PMID 12975480 DOI: 10.1172/JCI17533  0.56
2002 Neese RA, Misell LM, Turner S, Chu A, Kim J, Cesar D, Hoh R, Antelo F, Strawford A, McCune JM, Christiansen M, Hellerstein MK. Measurement in vivo of proliferation rates of slow turnover cells by 2H2O labeling of the deoxyribose moiety of DNA. Proceedings of the National Academy of Sciences of the United States of America. 99: 15345-50. PMID 12424339 DOI: 10.1073/pnas.232551499  0.56
2002 Bandsma RH, Rake JP, Visser G, Neese RA, Hellerstein MK, van Duyvenvoorde W, Princen HM, Stellaard F, Smit GP, Kuipers F. Increased lipogenesis and resistance of lipoproteins to oxidative modification in two patients with glycogen storage disease type 1a. The Journal of Pediatrics. 140: 256-60. PMID 11865283 DOI: 10.1067/mpd.2002.121382  0.56
2002 Deeks SG, Hoh R, Grant RM, Wrin T, Barbour JD, Narvaez A, Cesar D, Abe K, Hanley MB, Hellmann NS, Petropoulos CJ, McCune JM, Hellerstein MK. CD4+ T cell kinetics and activation in human immunodeficiency virus-infected patients who remain viremic despite long-term treatment with protease inhibitor-based therapy Journal of Infectious Diseases. 185: 315-323. PMID 11807713 DOI: 10.1086/338467  0.56
2000 Parks EJ, Dare D, Frazier KB, Hellerstein MK, Neese RA, Hughes E, Traber MG. Dependence of plasma alpha-tocopherol flux on very low-density triglyceride clearance in humans. Free Radical Biology & Medicine. 29: 1151-9. PMID 11121723 DOI: 10.1016/S0891-5849(00)00426-3  0.56
2000 Parks EJ, Hellerstein MK. Carbohydrate-induced hypertriacylglycerolemia: historical perspective and review of biological mechanisms. The American Journal of Clinical Nutrition. 71: 412-33. PMID 10648253  0.92
1999 Parks EJ, Krauss RM, Christiansen MP, Neese RA, Hellerstein MK. Effects of a low-fat, high-carbohydrate diet on VLDL-triglyceride assembly, production, and clearance. The Journal of Clinical Investigation. 104: 1087-96. PMID 10525047 DOI: 10.1172/JCI6572  0.56
1998 Siler SQ, Neese RA, Christiansen MP, Hellerstein MK. The inhibition of gluconeogenesis following alcohol in humans. American Journal of Physiology. Endocrinology and Metabolism. 275: E897-E907. PMID 29585213 DOI: 10.1152/ajpendo.1998.275.5.E897  0.56
1998 Siler SQ, Neese RA, Parks EJ, Hellerstein MK. VLDL-triglyceride production after alcohol ingestion, studied using [2-13C1] glycerol. Journal of Lipid Research. 39: 2319-28. PMID 9831620  0.92
1988 Hellerstein MK, Munro HN. Glycoconjugates as noninvasive probes of intrahepatic metabolism: III. Application to galactose assimilation by the intact rat. Metabolism: Clinical and Experimental. 37: 312-7. PMID 3357416  1
1987 Hellerstein MK, Munro HN. Glycoconjugates as noninvasive probes of intrahepatic metabolism: II. Application to measurement of plasma alpha 1-acid glycoprotein turnover during inflammation. Metabolism: Clinical and Experimental. 36: 995-1000. PMID 3657518  1
1987 Hellerstein MK, Greenblatt DJ, Munro HN. Glycoconjugates as noninvasive probes of intrahepatic metabolism: I. Kinetics of label incorporation with evidence of a common precursor UDP-glucose pool for secreted glycoconjugates. Metabolism: Clinical and Experimental. 36: 988-94. PMID 3657517  1
1986 Hellerstein MK, Greenblatt DJ, Munro HN. Glycoconjugates as noninvasive probes of intrahepatic metabolism: pathways of glucose entry into compartmentalized hepatic UDP-glucose pools during glycogen accumulation. Proceedings of the National Academy of Sciences of the United States of America. 83: 7044-8. PMID 3462741  1
1985 Hellerstein MK, Sasak V, Ordovas J, Munro HN. Isolation of alpha 1-acid glycoprotein from human plasma using high-performance liquid chromatography. Analytical Biochemistry. 146: 366-71. PMID 4025802  1
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