Uwe Rix, Ph.D. - Publications

Affiliations: 
2003 Medical University of South Carolina, Charleston, SC, United States 
Area:
Analytical Chemistry, Biochemistry, Molecular Biology

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Nerlakanti N, Yao J, Nguyen DT, Patel AK, Eroshkin AM, Lawrence HR, Ayaz M, Kuenzi BM, Agarwal N, Chen Y, Gunawan S, Karim RM, Berndt N, Puskas J, Magliocco AM, ... ... Rix U, et al. Targeting the BRD4-HOXB13 Co-regulated Transcriptional Networks with Bromodomain-Kinase Inhibitors to Suppress Metastatic Castration-Resistant Prostate Cancer. Molecular Cancer Therapeutics. PMID 30242092 DOI: 10.1158/1535-7163.MCT-18-0602  0.44
2017 Phadke M, Rix LLR, Smalley I, Bryant AT, Luo Y, Lawrence HR, Schaible BJ, Chen YA, Rix U, Smalley KSM. Dabrafenib inhibits the growth of BRAF-WT cancers through CDK16 and NEK9 inhibition. Molecular Oncology. PMID 29112787 DOI: 10.1002/1878-0261.12152  0.44
2016 Li J, Fang B, Kinose F, Bai Y, Kim JY, Chen YA, Rix U, Koomen JM, Haura EB. Target identification in small cell lung cancer via integrated phenotypic screening and activity-based protein profiling. Molecular Cancer Therapeutics. PMID 26772203 DOI: 10.1158/1535-7163.MCT-15-0444  0.44
2015 Sumi NJ, Kuenzi BM, Knezevic CE, Remsing Rix LL, Rix U. Chemoproteomics Reveals Novel Protein and Lipid Kinase Targets of Clinical CDK4/6 Inhibitors in Lung Cancer. Acs Chemical Biology. PMID 26390342 DOI: 10.1021/acschembio.5b00368  0.44
2015 Haura EB, Beg AA, Rix U, Antonia S. Charting Immune Signaling Proteomes En Route to New Therapeutic Strategies. Cancer Immunology Research. 3: 714-20. PMID 26081226 DOI: 10.1158/2326-6066.CIR-15-0094  0.44
2015 Fang B, Hoffman MA, Mirza AS, Mishall KM, Li J, Peterman SM, Smalley KS, Shain KH, Weinberger PM, Wu J, Rix U, Haura EB, Koomen JM. Evaluating kinase ATP uptake and tyrosine phosphorylation using multiplexed quantification of chemically labeled and post-translationally modified peptides. Methods (San Diego, Calif.). 81: 41-9. PMID 25782629 DOI: 10.1016/j.ymeth.2015.03.006  0.44
2015 Muellner MK, Mair B, Ibrahim Y, Kerzendorfer C, Lechtermann H, Trefzer C, Klepsch F, Müller AC, Leitner E, Macho-Maschler S, Superti-Furga G, Bennett KL, Baselga J, Rix U, Kubicek S, et al. Targeting a cell state common to triple-negative breast cancers. Molecular Systems Biology. 11: 789. PMID 25699542 DOI: 10.15252/msb.20145664  0.44
2014 Bai Y, Kim JY, Watters JM, Fang B, Kinose F, Song L, Koomen JM, Teer JK, Fisher K, Chen YA, Rix U, Haura EB. Adaptive responses to dasatinib-treated lung squamous cell cancer cells harboring DDR2 mutations. Cancer Research. 74: 7217-28. PMID 25348954 DOI: 10.1158/0008-5472.CAN-14-0505  0.44
2014 Gridling M, Ficarro SB, Breitwieser FP, Song L, Parapatics K, Colinge J, Haura EB, Marto JA, Superti-Furga G, Bennett KL, Rix U. Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics. Molecular Cancer Therapeutics. 13: 2751-62. PMID 25189542 DOI: 10.1158/1535-7163.MCT-14-0152  0.44
2014 Yang H, Lawrence HR, Kazi A, Gevariya H, Patel R, Luo Y, Rix U, Schonbrunn E, Lawrence NJ, Sebti SM. Dual aurora a and jak2 kinase blockade effectively suppresses malignant transformation Oncotarget. 5: 2947-2961. PMID 24930769  0.44
2014 Remsing Rix LL, Kuenzi BM, Luo Y, Remily-Wood E, Kinose F, Wright G, Li J, Koomen JM, Haura EB, Lawrence HR, Rix U. GSK3 alpha and beta are new functionally relevant targets of tivantinib in lung cancer cells Acs Chemical Biology. 9: 353-358. PMID 24215125 DOI: 10.1021/cb400660a  0.44
2013 Li J, Bennett K, Stukalov A, Fang B, Zhang G, Yoshida T, Okamoto I, Kim JY, Song L, Bai Y, Qian X, Rawal B, Schell M, Grebien F, Winter G, ... Rix U, et al. Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms. Molecular Systems Biology. 9: 705. PMID 24189400 DOI: 10.1038/msb.2013.61  0.44
2013 Kim JY, Welsh EA, Oguz U, Fang B, Bai Y, Kinose F, Bronk C, Remsing Rix LL, Beg AA, Rix U, Eschrich SA, Koomen JM, Haura EB. Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 12414-9. PMID 23836654 DOI: 10.1073/pnas.1220674110  0.44
2012 Winter GE, Rix U, Carlson SM, Gleixner KV, Grebien F, Gridling M, Müller AC, Breitwieser FP, Bilban M, Colinge J, Valent P, Bennett KL, White FM, Superti-Furga G. Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML. Nature Chemical Biology. 8: 905-12. PMID 23023260 DOI: 10.1038/nchembio.1085  0.44
2012 Brandt O, Mildner M, Egger AE, Groessl M, Rix U, Posch M, Keppler BK, Strupp C, Mueller B, Stingl G. Nanoscalic silver possesses broad-spectrum antimicrobial activities and exhibits fewer toxicological side effects than silver sulfadiazine. Nanomedicine : Nanotechnology, Biology, and Medicine. 8: 478-88. PMID 21839058 DOI: 10.1016/j.nano.2011.07.005  0.44
2011 Gleixner KV, Mayerhofer M, Cerny-Reiterer S, Hörmann G, Rix U, Bennett KL, Hadzijusufovic E, Meyer RA, Pickl WF, Gotlib J, Horny HP, Reiter A, Mitterbauer-Hohendanner G, Superti-Furga G, Valent P. KIT-D816V-independent oncogenic signaling in neoplastic cells in systemic mastocytosis: role of Lyn and Btk activation and disruption by dasatinib and bosutinib. Blood. 118: 1885-98. PMID 21680801 DOI: 10.1182/blood-2010-06-289959  0.44
2010 Ubaida Mohien C, Hartler J, Breitwieser F, Rix U, Remsing Rix L, Winter GE, Thallinger GG, Bennett KL, Superti-Furga G, Trajanoski Z, Colinge J. MASPECTRAS 2: An integration and analysis platform for proteomic data. Proteomics. 10: 2719-22. PMID 20455215 DOI: 10.1002/pmic.201000075  0.44
2010 Li J, Rix U, Fang B, Bai Y, Edwards A, Colinge J, Bennett KL, Gao J, Song L, Eschrich S, Superti-Furga G, Koomen J, Haura EB. A chemical and phosphoproteomic characterization of dasatinib action in lung cancer Nature Chemical Biology. 6: 291-299. PMID 20190765 DOI: 10.1038/nchembio.332  0.44
2005 Zheng JT, Rix U, Zhao L, Mattingly C, Adams V, Chen Q, Rohr J, Yang KQ. Cytotoxic activities of new jadomycin derivatives. The Journal of Antibiotics. 58: 405-8. PMID 16156517 DOI: 10.1038/ja.2005.51  0.48
2005 Chen YH, Wang CC, Greenwell L, Rix U, Hoffmeister D, Vining LC, Rohr J, Yang KQ. Functional analyses of oxygenases in jadomycin biosynthesis and identification of JadH as a bifunctional oxygenase/dehydrase Journal of Biological Chemistry. 280: 22508-22514. PMID 15817470 DOI: 10.1074/jbc.M414229200  0.44
2005 Rix U, Wang C, Chen Y, Lipata FM, Rix LLR, Greenwell LM, Vining LC, Yang K, Rohr J. The oxidative ring cleavage in jadomycin biosynthesis: A multistep oxygenation cascade in a biosynthetic black box Chembiochem. 6: 838-845. PMID 15776503 DOI: 10.1002/cbic.200400395  0.44
2005 Zhu L, Ostash B, Rix U, Nur-E-Alam M, Mayers A, Luzhetskyy A, Mendez C, Salas JA, Bechthold A, Fedorenko V, Rohr J. Identification of the function of gene lndM2 encoding a bifunctional oxygenase-reductase involved in the biosynthesis of the antitumor antibiotic landomycin E by Streptomyces globisporus 1912 supports the originally assigned structure for landomycinone. The Journal of Organic Chemistry. 70: 631-8. PMID 15651811 DOI: 10.1021/jo0483623  0.44
2004 Ostash B, Rix U, Rix LL, Liu T, Lombo F, Luzhetskyy A, Gromyko O, Wang C, Braña AF, Méndez C, Salas JA, Fedorenko V, Rohr J. Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus. Chemistry & Biology. 11: 547-55. PMID 15123249 DOI: 10.1016/j.chembiol.2004.03.011  0.48
2004 Rix U, Zheng J, Remsing Rix LL, Greenwell L, Yang K, Rohr J. The dynamic structure of jadomycin B and the amino acid incorporation step of its biosynthesis. Journal of the American Chemical Society. 126: 4496-7. PMID 15070349 DOI: 10.1021/ja031724o  0.48
2003 Remsing LL, González AM, Nur-e-Alam M, Fernández-Lozano MJ, Braña AF, Rix U, Oliveira MA, Méndez C, Salas JA, Rohr J. Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis. Journal of the American Chemical Society. 125: 5745-53. PMID 12733914 DOI: 10.1021/ja034162h  0.48
2003 Rix U, Remsing LL, Hoffmeister D, Bechthold A, Rohr J. Urdamycin L: a novel metabolic shunt product that provides evidence for the role of the urdM gene in the urdamycin A biosynthetic pathway of Streptomyces fradiae TU 2717. Chembiochem : a European Journal of Chemical Biology. 4: 109-11. PMID 12512084 DOI: 10.1002/cbic.200390002  0.48
2002 Rix U, Fischer C, Remsing LL, Rohr J. Modification of post-PKS tailoring steps through combinatorial biosynthesis. Natural Product Reports. 19: 542-80. PMID 12430723 DOI: 10.1039/b103920m  0.44
2002 Trefzer A, Blanco G, Remsing L, Künzel E, Rix U, Lipata F, Braña AF, Méndez C, Rohr J, Bechthold A, Salas JA. Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways. Journal of the American Chemical Society. 124: 6056-62. PMID 12022840  0.48
2002 Macky TA, Oelkers C, Rix U, Heredia ML, Künzel E, Wimberly M, Rohrer B, Crosson CE, Rohr J. Synthesis, pharmacokinetics, efficacy, and rat retinal toxicity of a novel mitomycin C-triamcinolone acetonide conjugate. Journal of Medicinal Chemistry. 45: 1122-7. PMID 11855992 DOI: 10.1021/jm010511b  0.44
2002 Remsing LL, Garcia-Bernardo J, Gonzalez A, Künzel E, Rix U, Braña AF, Bearden DW, Méndez C, Salas JA, Rohr J. Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway. Journal of the American Chemical Society. 124: 1606-14. PMID 11853433  0.48
2000 Trefzer A, Hoffmeister D, Künzel E, Stockert S, Weitnauer G, Westrich L, Rix U, Fuchser J, Bindseil KU, Rohr J, Bechthold A. Function of glycosyltransferase genes involved in urdamycin A biosynthesis. Chemistry & Biology. 7: 133-42. PMID 10662691  0.48
Show low-probability matches.