Peter C. Keng - Publications

Affiliations: 
University of Rochester, Rochester, NY 
Area:
Molecular Biology, Radiation Chemistry, Pathology
Website:
https://www.urmc.rochester.edu/people/20021894-peter-c-keng

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Chen X, Chen F, Ren Y, Weng G, Keng PC, Chen Y, Lee SO. Glucocorticoid receptor upregulation increases radioresistance and triggers androgen independence of prostate cancer. The Prostate. PMID 31334877 DOI: 10.1002/pros.23861  0.32
2019 Chen F, Chen X, Ren Y, Weng G, Keng PC, Chen Y, Lee SO. Radiation-induced glucocorticoid receptor promotes CD44+ prostate cancer stem cell growth through activation of SGK1-Wnt/β-catenin signaling. Journal of Molecular Medicine (Berlin, Germany). PMID 31187175 DOI: 10.1007/s00109-019-01807-8  0.32
2019 Chen X, Chen F, Ren Y, Weng G, Xu L, Xue X, Keng PC, Lee SO, Chen Y. IL-6 signaling contributes to radioresistance of prostate cancer through key DNA repair-associated molecules ATM, ATR, and BRCA 1/2. Journal of Cancer Research and Clinical Oncology. PMID 31020420 DOI: 10.1007/s00432-019-02917-z  0.32
2018 Zhu R, Xue X, Shen M, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y. NFκB and TNFα as individual key molecules associated with the cisplatin-resistance and radioresistance of lung cancer. Experimental Cell Research. PMID 30508513 DOI: 10.1016/j.yexcr.2018.11.022  0.32
2018 Zhu R, Yang X, Xue X, Shen M, Chen F, Chen X, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y. Neuroendocrine differentiation contributes to radioresistance development and metastatic potential increase in non-small cell lung cancer. Biochimica Et Biophysica Acta. Molecular Cell Research. 1865: 1878-1890. PMID 30262435 DOI: 10.1016/j.bbamcr.2018.09.005  0.32
2018 Shen M, Chen Y, Xu L, Zhu R, Xue X, Tsai Y, Keng PC, Lee SO, Chen Y. Increased infiltration of macrophages to radioresistant lung cancer cells contributes to the development of the additional resistance of tumor cells to the cytotoxic effects of NK cells. International Journal of Oncology. PMID 29750425 DOI: 10.3892/ijo.2018.4394  0.32
2018 Xu L, Shen M, Chen X, Yang DR, Tsai Y, Keng PC, Lee SO, Chen Y. In vitro-induced M2 type macrophages induces the resistance of prostate cancer cells to cytotoxic action of NK cells. Experimental Cell Research. PMID 29408565 DOI: 10.1016/j.yexcr.2018.01.041  0.32
2018 Xu L, Shen M, Chen X, Zhu R, Yang DR, Tsai Y, Keng PC, Chen Y, Lee SO. Adipocytes affect castration-resistant prostate cancer cells to develop the resistance to cytotoxic action of NK cells with alterations of PD-L1/NKG2D ligand levels in tumor cells. The Prostate. PMID 29330929 DOI: 10.1002/pros.23479  0.32
2018 Shen M, Tsai Y, Zhu R, Keng PC, Chen Y, Chen Y, Lee SO. FASN-TGF-β1-PD-L1 axis contributes to the development of resistance to NK cell cytotoxicity of cisplatin-resistant lung cancer cells. Biochimica Et Biophysica Acta. PMID 29306075 DOI: 10.1016/j.bbalip.2017.12.012  0.32
2017 Shen MJ, Xu LJ, Yang L, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y. Radiation alters PD-L1/NKG2D ligand levels in lung cancer cells and leads to immune escape from NK cell cytotoxicity via IL-6-MEK/Erk signaling pathway. Oncotarget. 8: 80506-80520. PMID 29113321 DOI: 10.18632/oncotarget.19193  0.32
2017 Xu L, Chen X, Shen M, Yang DR, Fang L, Weng G, Tsai Y, Keng PC, Chen Y, Lee SO. Inhibition of IL-6-JAK/Stat3 signaling in castration-resistant prostate cancer cells enhances the NK cell mediated cytotoxicity via alteration of PD-L1/NKG2D ligand levels. Molecular Oncology. PMID 28865178 DOI: 10.1002/1878-0261.12135  0.32
2017 Yang L, Shen M, Xu LJ, Yang X, Tsai Y, Keng PC, Chen Y, Lee SO. Enhancing NK cell-mediated cytotoxicity to cisplatin-resistant lung cancer cells via MEK/Erk signaling inhibition. Scientific Reports. 7: 7958. PMID 28801607 DOI: 10.1038/s41598-017-08483-z  0.32
2017 Shen MJ, Xu LJ, Yang L, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y. Radiation alters PD-L1/NKG2D ligand levels in lung cancer cells and leads to immune escape from NK cell cytotoxicity via IL-6-MEK/Erk signaling pathway. Oncotarget. PMID 28732383 DOI: 10.18632/oncotarget.19193  0.32
2017 Zhang F, Shen M, Yang L, Yang X, Tsai Y, Keng PC, Chen Y, Lee SO, Chen Y. Simultaneous targeting of ATM and Mcl-1 increases cisplatin sensitivity of cisplatin-resistant non-small cell lung cancer. Cancer Biology & Therapy. 0. PMID 28686074 DOI: 10.1080/15384047.2017.1345391  0.32
2017 Wang X, Yang X, Tsai Y, Yang L, Chuang KH, Keng PC, Lee SO, Chen Y. IL-6 Mediates Macrophage Infiltration after Irradiation via Up-regulation of CCL2/CCL5 in Non-small Cell Lung Cancer. Radiation Research. PMID 28054838 DOI: 10.1667/RR14503.1  0.32
2016 Yang L, Zhang F, Wang X, Tsai Y, Chuang KH, Keng PC, Lee SO, Chen Y. A FASN-TGF-β1-FASN regulatory loop contributes to high EMT/metastatic potential of cisplatin-resistant non-small cell lung cancer. Oncotarget. 55543-55554. PMID 27765901 DOI: 10.18632/oncotarget.10837  0.32
2016 Zhang F, Duan S, Tsai Y, Keng P, Chen Y, Lee SO, Chen Y. Cisplatin treatment increases stemness via up-regulation of hypoxia inducible factors by IL-6 in non-small cell lung cancer. Cancer Science. PMID 27009878 DOI: 10.1111/cas.12937  0.32
2014 Chen Y, Nowak I, Huang J, Keng PC, Sun H, Xu H, Wei G, Lee SO. Erk/MAP kinase signaling pathway and neuroendocrine differentiation of non-small-cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 50-8. PMID 24346093 DOI: 10.1097/JTO.0000000000000034  0.32
2012 O'Reilly MA, Yee M, Buczynski BW, Vitiello PF, Keng PC, Welle SL, Finkelstein JN, Dean DA, Lawrence BP. Neonatal oxygen increases sensitivity to influenza A virus infection in adult mice by suppressing epithelial expression of Ear1. The American Journal of Pathology. 181: 441-51. PMID 22677423 DOI: 10.1016/j.ajpath.2012.05.005  0.48
2011 Chen Y, Pandya KJ, Hyrien O, Keng PC, Smudzin T, Anderson J, Qazi R, Smith B, Watson TJ, Feins RH, Johnstone DW. Preclinical and pilot clinical studies of docetaxel chemoradiation for Stage III non-small-cell lung cancer. International Journal of Radiation Oncology, Biology, Physics. 80: 1358-64. PMID 20708854 DOI: 10.1016/j.ijrobp.2010.04.060  0.32
2009 Tsai CH, Chiu SJ, Liu CC, Sheu TJ, Hsieh CH, Keng PC, Lee YJ. Regulated expression of cofilin and the consequent regulation of p27(kip1) are essential for G(1) phase progression. Cell Cycle (Georgetown, Tex.). 8: 2365-74. PMID 19556892 DOI: 10.4161/cc.8.15.9072  0.92
2009 Lee YJ, Tsai CH, Hwang JJ, Chiu SJ, Sheu TJ, Keng PC. Involvement of a p53-independent and post-transcriptional up-regulation for p21WAF/CIP1 following destabilization of the actin cytoskeleton. International Journal of Oncology. 34: 581-9. PMID 19148495  0.92
2008 Zhang H, Hyrien O, Pandya KJ, Keng PC, Chen Y. Tumor response kinetics after schedule-dependent paclitaxel chemoradiation treatment for inoperable non-small cell lung cancer: a model for low-dose chemotherapy radiosensitization. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 3: 563-8. PMID 18520792 DOI: 10.1097/JTO.0b013e3181729dbe  0.32
2008 Vitiello PF, Staversky RJ, Keng PC, O'Reilly MA. PUMA inactivation protects against oxidative stress through p21/Bcl-XL inhibition of bax death. Free Radical Biology & Medicine. 44: 367-74. PMID 18215742 DOI: 10.1016/j.freeradbiomed.2007.09.021  0.48
2008 Chen Y, Pandya KJ, Feins R, Johnstone DW, Watson T, Smudzin T, Keng PC. Toxicity profile and pharmacokinetic study of a phase I low-dose schedule-dependent radiosensitizing paclitaxel chemoradiation regimen for inoperable non-small-cell lung cancer. International Journal of Radiation Oncology, Biology, Physics. 71: 407-13. PMID 18164866 DOI: 10.1016/j.ijrobp.2007.10.011  0.32
2007 Gehen SC, Vitiello PF, Bambara RA, Keng PC, O'Reilly MA. Downregulation of PCNA potentiates p21-mediated growth inhibition in response to hyperoxia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L716-24. PMID 17085526 DOI: 10.1152/ajplung.00135.2006  0.48
2006 Staversky RJ, Vitiello PF, Gehen SC, Helt CE, Rahman A, Keng PC, O'Reilly MA. p21(Cip1/Waf1/Sdi1) protects against hyperoxia by maintaining expression of Bcl-X(L). Free Radical Biology & Medicine. 41: 601-9. PMID 16863993 DOI: 10.1016/j.freeradbiomed.2006.04.029  0.48
2006 Brandt PD, Helt CE, Keng PC, Bambara RA. The Rad9 protein enhances survival and promotes DNA repair following exposure to ionizing radiation. Biochemical and Biophysical Research Communications. 347: 232-7. PMID 16814252 DOI: 10.1016/j.bbrc.2006.06.064  0.48
2006 Chen MF, Keng PC, Shau H, Wu CT, Hu YC, Liao SK, Chen WC. Inhibition of lung tumor growth and augmentation of radiosensitivity by decreasing peroxiredoxin I expression. International Journal of Radiation Oncology, Biology, Physics. 64: 581-91. PMID 16414373 DOI: 10.1016/j.ijrobp.2005.10.012  0.32
2005 Chen MF, Keng PC, Lin PY, Yang CT, Liao SK, Chen WC. Caffeic acid phenethyl ester decreases acute pneumonitis after irradiation in vitro and in vivo. Bmc Cancer. 5: 158. PMID 16336675 DOI: 10.1186/1471-2407-5-158  0.32
2005 Lee YJ, Mazzatti DJ, Yun Z, Keng PC. Inhibition of invasiveness of human lung cancer cell line H1299 by over-expression of cofilin. Cell Biology International. 29: 877-83. PMID 16301112 DOI: 10.1016/j.cellbi.2005.07.005  0.92
2005 Lee YJ, Keng PC. Studying the effects of actin cytoskeletal destabilization on cell cycle by cofilin overexpression. Molecular Biotechnology. 31: 1-10. PMID 16118410 DOI: 10.1385/MB:31:1:001  0.92
2005 Lee YJ, Sheu TJ, Keng PC. Enhancement of radiosensitivity in H1299 cancer cells by actin-associated protein cofilin. Biochemical and Biophysical Research Communications. 335: 286-91. PMID 16061204 DOI: 10.1016/j.bbrc.2005.07.073  0.92
2005 Helt CE, Wang W, Keng PC, Bambara RA. Evidence that DNA damage detection machinery participates in DNA repair. Cell Cycle (Georgetown, Tex.). 4: 529-32. PMID 15876866  0.48
2005 Mazzatti DJ, Lee YJ, Helt CE, O'Reilly MA, Keng PC. p53 modulates radiation sensitivity independent of p21 transcriptional activation. American Journal of Clinical Oncology. 28: 43-50. PMID 15685034  0.92
2005 Helt CE, Cliby WA, Keng PC, Bambara RA, O'Reilly MA. Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage. The Journal of Biological Chemistry. 280: 1186-92. PMID 15533933 DOI: 10.1074/jbc.M410873200  0.48
2004 Chen MF, Wu CT, Chen YJ, Keng PC, Chen WC. Cell killing and radiosensitization by caffeic acid phenethyl ester (CAPE) in lung cancer cells. Journal of Radiation Research. 45: 253-60. PMID 15304968 DOI: JST.JSTAGE/jrr/45.253  0.32
2004 Roper JM, Mazzatti DJ, Watkins RH, Maniscalco WM, Keng PC, O'Reilly MA. In vivo exposure to hyperoxia induces DNA damage in a population of alveolar type II epithelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L1045-54. PMID 14729512 DOI: 10.1152/ajplung.00376.2003  0.8
2004 Helt CE, Staversky RJ, Lee YJ, Bambara RA, Keng PC, O'Reilly MA. The Cdk and PCNA domains on p21Cip1 both function to inhibit G1/S progression during hyperoxia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L506-13. PMID 12936910 DOI: 10.1152/ajplung.00243.2003  0.92
2003 Roper JM, Staversky RJ, Finkelstein JN, Keng PC, O'Reilly MA. Identification and isolation of mouse type II cells on the basis of intrinsic expression of enhanced green fluorescent protein. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L691-700. PMID 12740214 DOI: 10.1152/ajplung.00034.2003  0.48
2003 Chen Y, Pandya K, Keng PC, Johnstone D, Li J, Lee YJ, Smudzin T, Okunieff P. Phase I/II clinical study of pulsed paclitaxel radiosensitization for thoracic malignancy: a therapeutic approach on the basis of preclinical research of human cancer cell lines. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 969-75. PMID 12631594  0.92
2003 O'Reilly MA, Staversky RJ, Finkelstein JN, Keng PC. Activation of the G2 cell cycle checkpoint enhances survival of epithelial cells exposed to hyperoxia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L368-75. PMID 12388347 DOI: 10.1152/ajplung.00299.2002  0.48
2002 Rancourt RC, Hayes DD, Chess PR, Keng PC, O'Reilly MA. Growth arrest in G1 protects against oxygen-induced DNA damage and cell death. Journal of Cellular Physiology. 193: 26-36. PMID 12209877 DOI: 10.1002/jcp.10146  0.48
2001 Rancourt RC, Keng PC, Helt CE, O'Reilly MA. The role of p21(CIP1/WAF1) in growth of epithelial cells exposed to hyperoxia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 280: L617-26. PMID 11238001  0.48
1999 Rancourt RC, Staversky RJ, Keng PC, O'Reilly MA. Hyperoxia inhibits proliferation of Mv1Lu epithelial cells independent of TGF-beta signaling. The American Journal of Physiology. 277: L1172-8. PMID 10600888  0.48
1987 Lett JT, Keng PC, Bergtold DS, Howard J. Effects of heavy ions on rabbit tissues: induction of DNA strand breaks in retinal photoreceptor cells by high doses of radiation. Radiation and Environmental Biophysics. 26: 23-36. PMID 3588835  1
1986 Lett JT, Bertold DS, Keng PC. Effects of LET infinity on the fate of DNA damage induced in rabbit sensory cells in situ: fundamental aspects. Basic Life Sciences. 38: 139-50. PMID 3741328  1
1984 Lett JT, Bergtold DS, Cox AB, Keng PC, Okayasu R. Further evidence that the survival of irradiated mammalian cells is controlled by temporal processes. The British Journal of Cancer. Supplement. 6: 163-8. PMID 6582903  1
1983 Keng PC, Bergtold DS, Lett JT. Effects of heavy ions on rabbit tissues: analysis of low levels of DNA damage in retinal photoreceptor cells. International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine. 43: 219-29. PMID 6601074  1
1982 Cox AB, Keng PC, Lee AC, Lett JT. Effects of heavy ions on rabbit tissues: damage to the forebrain. International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine. 42: 355-67. PMID 6983506  1
1982 Keng PC, Lee AC, Cox AB, Bergtold DS, Lett JT. Effects of heavy ions on rabbit tissues: cataractogenesis. International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine. 41: 127-37. PMID 6978307  1
1981 Cox AB, Keng PC, Glass NL, Lett JT. Effects of heavy ions on rabbit tissues: alopecia. International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine. 40: 645-57. PMID 6978301  1
1981 Keng PC, Lett JT. Effects of heavy ions on rabbit tissues: loss of electroretinogram and DNA repair in retinal photoreceptor cells. International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine. 39: 655-64. PMID 6972931  1
1980 Lett JT, Cox AB, Keng PC, Lee AC, Su CM, Bergtold DS. Late degeneration in rabbit tissues after irradiation by heavy ions. Life Sciences and Space Research. 18: 131-42. PMID 11968209  1
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