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Thomas J. Wandless - Publications

Stanford University, Palo Alto, CA 
biological chemistry

78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Miyamae Y, Chen LC, Utsugi Y, Farrants H, Wandless TJ. A Method for Conditional Regulation of Protein Stability in Native or Near-Native Form. Cell Chemical Biology. PMID 33007216 DOI: 10.1016/j.chembiol.2020.09.004  0.8
2016 Navarro R, Chen LC, Rakhit R, Wandless TJ. A Novel Destabilizing Domain Based on a Small-Molecule Dependent Fluorophore. Acs Chemical Biology. PMID 27243964 DOI: 10.1021/acschembio.6b00234  0.8
2016 Miyazaki Y, Mizumoto K, Dey G, Kudo T, Perrino J, Chen LC, Meyer T, Wandless TJ. A method to rapidly create protein aggregates in living cells. Nature Communications. 7: 11689. PMID 27229621 DOI: 10.1038/ncomms11689  0.8
2015 Miyazaki Y, Chen LC, Chu BW, Swigut T, Wandless TJ. Distinct transcriptional responses elicited by unfolded nuclear or cytoplasmic protein in mammalian cells. Elife. 4. PMID 26314864 DOI: 10.7554/eLife.07687  1
2015 Collins SR, Yang HW, Bonger KM, Guignet EG, Wandless TJ, Meyer T. Using light to shape chemical gradients for parallel and automated analysis of chemotaxis. Molecular Systems Biology. 11: 804. PMID 25908733 DOI: 10.15252/msb.20156027  1
2015 Collins SR, Yang HW, Bonger KM, Guignet EG, Wandless TJ, Meyer T. Using light to shape chemical gradients for parallel and automated analysis of chemotaxis Molecular Systems Biology. 11: 1-13. DOI: 10.15252/msb.20156027  1
2014 Rakhit R, Navarro R, Wandless TJ. Chemical biology strategies for posttranslational control of protein function. Chemistry & Biology. 21: 1238-52. PMID 25237866 DOI: 10.1016/j.chembiol.2014.08.011  0.36
2014 Webb SJ. Neonatal factors associated with autism spectrum disorders in infants. Evidence-Based Mental Health. 17: 106. PMID 24785736 DOI: 10.1136/eb-2014-101763  1
2014 Bonger KM, Rakhit R, Payumo AY, Chen JK, Wandless TJ. General method for regulating protein stability with light. Acs Chemical Biology. 9: 111-5. PMID 24180414 DOI: 10.1021/cb400755b  1
2014 Rakhit R, Navarro R, Wandless TJ. Chemical biology strategies for posttranslational control of protein function Chemistry and Biology. 21: 1238-1252. DOI: 10.1016/j.chembiol.2014.08.011  1
2013 Chu BW, Kovary KM, Guillaume J, Chen LC, Teruel MN, Wandless TJ. The E3 ubiquitin ligase UBE3C enhances proteasome processivity by ubiquitinating partially proteolyzed substrates. The Journal of Biological Chemistry. 288: 34575-87. PMID 24158444 DOI: 10.1074/jbc.M113.499350  1
2013 Sando R, Baumgaertel K, Pieraut S, Torabi-Rander N, Wandless TJ, Mayford M, Maximov A. Inducible control of gene expression with destabilized Cre. Nature Methods. 10: 1085-8. PMID 24056874 DOI: 10.1038/nmeth.2640  1
2013 Cho U, Zimmerman SM, Chen LC, Owen E, Kim JV, Kim SK, Wandless TJ. Rapid and tunable control of protein stability in Caenorhabditis elegans using a small molecule. Plos One. 8: e72393. PMID 23991108 DOI: 10.1371/journal.pone.0072393  1
2013 Spiekerkoetter E, Tian X, Cai J, Hopper RK, Sudheendra D, Li CG, El-Bizri N, Sawada H, Haghighat R, Chan R, Haghighat L, de Jesus Perez V, Wang L, Reddy S, Zhao M, ... ... Wandless TJ, et al. FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension. The Journal of Clinical Investigation. 123: 3600-13. PMID 23867624 DOI: 10.1172/JCI65592  1
2013 Alvarez JV, Pan Tc, Ruth J, Feng Y, Zhou A, Pant D, Grimley JS, Wandless TJ, DeMichele A, Chodosh LA. Par-4 Downregulation Promotes Breast Cancer Recurrence by Preventing Multinucleation following Targeted Therapy Cancer Cell. 24: 30-44. PMID 23770012 DOI: 10.1016/j.ccr.2013.05.007  1
2013 Sellmyer MA, Bronsart L, Imoto H, Contag CH, Wandless TJ, Prescher JA. Visualizing cellular interactions with a generalized proximity reporter. Proceedings of the National Academy of Sciences of the United States of America. 110: 8567-72. PMID 23650381 DOI: 10.1073/pnas.1218336110  1
2012 Watanabe K, Al-Bassam S, Miyazaki Y, Wandless TJ, Webster P, Arnold DB. Networks of polarized actin filaments in the axon initial segment provide a mechanism for sorting axonal and dendritic proteins. Cell Reports. 2: 1546-53. PMID 23246006 DOI: 10.1016/j.celrep.2012.11.015  1
2012 Sellmyer MA, Chen Lc, Egeler EL, Rakhit R, Wandless TJ. Intracellular Context Affects Levels of a Chemically Dependent Destabilizing Domain Plos One. 7. PMID 22984418 DOI: 10.1371/journal.pone.0043297  1
2012 Al-Bassam S, Xu M, Wandless TJ, Arnold DB. Differential trafficking of transport vesicles contributes to the localization of dendritic proteins. Cell Reports. 2: 89-100. PMID 22840400 DOI: 10.1016/j.celrep.2012.05.018  1
2012 Miyazaki Y, Imoto H, Chen LC, Wandless TJ. Destabilizing domains derived from the human estrogen receptor Journal of the American Chemical Society. 134: 3942-3945. PMID 22332638 DOI: 10.1021/ja209933r  1
2012 Leong HS, Lizardo MM, Ablack A, McPherson VA, Wandless TJ, Chambers AF, Lewis JD. Imaging the impact of chemically inducible proteins on cellular dynamics in vivo. Plos One. 7: e30177. PMID 22276156 DOI: 10.1371/journal.pone.0030177  1
2011 Egeler EL, Urner LM, Rakhit R, Liu CW, Wandless TJ. Ligand-switchable substrates for a ubiquitin-proteasome system Journal of Biological Chemistry. 286: 31328-31336. PMID 21768107 DOI: 10.1074/jbc.M111.264101  1
2011 Rakhit R, Edwards SR, Iwamoto M, Wandless TJ. Evaluation of FKBP and DHFR based destabilizing domains in Saccharomyces cerevisiae Bioorganic and Medicinal Chemistry Letters. 21: 4965-4968. PMID 21741238 DOI: 10.1016/j.bmcl.2011.06.006  1
2011 Bonger KM, Chen LC, Liu CW, Wandless TJ. Small-molecule displacement of a cryptic degron causes conditional protein degradation Nature Chemical Biology. 7: 531-537. PMID 21725303 DOI: 10.1038/nchembio.598  1
2011 Muralidharan V, Oksman A, Iwamoto M, Wandless TJ, Goldberg DE. Asparagine repeat function in a Plasmodium falciparum protein assessed via a regulatable fluorescent affinity tag. Proceedings of the National Academy of Sciences of the United States of America. 108: 4411-6. PMID 21368162 DOI: 10.1073/pnas.1018449108  1
2011 Kwan MD, Sellmyer MA, Quarto N, Ho AM, Wandless TJ, Longaker MT. Chemical control of FGF-2 release for promoting calvarial healing with adipose stem cells Journal of Biological Chemistry. 286: 11307-11313. PMID 21262969 DOI: 10.1074/jbc.M110.180042  1
2010 Iwamoto M, Björklund T, Lundberg C, Kirik D, Wandless TJ. A general chemical method to regulate protein stability in the mammalian central nervous system. Chemistry & Biology. 17: 981-8. PMID 20851347 DOI: 10.1016/j.chembiol.2010.07.009  1
2010 Dvorin JD, Martyn DC, Patel SD, Grimley JS, Collins CR, Hopp CS, Bright AT, Westenberger S, Winzeler E, Blackman MJ, Baker DA, Wandless TJ, Duraisingh MT. A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes. Science (New York, N.Y.). 328: 910-2. PMID 20466936 DOI: 10.1126/science.1188191  1
2010 Edwards SR, Wandless TJ. Dicistronic regulation of fluorescent proteins in the budding yeast Saccharomyces cerevisiae Yeast. 27: 229-236. PMID 20017217 DOI: 10.1002/yea.1744  1
2009 Sellmyer MA, Thorne SH, Banaszynski LA, Contag CH, Wandless TJ. A general method for conditional regulation of protein stability in living animals. Cold Spring Harbor Protocols. 2009: pdb.prot5173. PMID 20147108 DOI: 10.1101/pdb.prot5173  1
2009 Hagan EL, Banaszynski LA, Chen LC, Maynard-Smith LA, Wandless TJ. Regulating protein stability in mammalian cells using small molecules. Cold Spring Harbor Protocols. 2009: pdb.prot5172. PMID 20147107 DOI: 10.1101/pdb.prot5172  0.88
2009 Wandless TJ. The proteasome makes sense of mixed signals Nature Chemical Biology. 5: 3-4. PMID 19088709 DOI: 10.1038/nchembio0109-3  1
2009 Hagan EL, Banaszynski LA, Chen LC, Maynard-Smith LA, Wandless TJ. Regulating protein stability in mammalian cells using small molecules Cold Spring Harbor Protocols. 4. DOI: 10.1101/pdb.prot5172  1
2008 Banaszynski LA, Sellmyer MA, Contag CH, Wandless TJ, Thorne SH. Chemical control of protein stability and function in living mice. Nature Medicine. 14: 1123-7. PMID 18836461 DOI: 10.1038/nm.1754  1
2008 Chu BW, Banaszynski LA, Chen LC, Wandless TJ. Recent progress with FKBP-derived destabilizing domains. Bioorganic & Medicinal Chemistry Letters. 18: 5941-4. PMID 18815033 DOI: 10.1016/j.bmcl.2008.09.043  1
2008 Grimley JS, Chen DA, Banaszynski LA, Wandless TJ. Synthesis and analysis of stabilizing ligands for FKBP-derived destabilizing domains Bioorganic and Medicinal Chemistry Letters. 18: 759-761. PMID 18039574 DOI: 10.1016/j.bmcl.2007.11.044  1
2007 Herm-Götz A, Agop-Nersesian C, Münter S, Grimley JS, Wandless TJ, Frischknecht F, Meissner M. Rapid control of protein level in the apicomplexan Toxoplasma gondii Nature Methods. 4: 1003-1005. PMID 17994029 DOI: 10.1038/nmeth1134  1
2007 Grimley JS, Sawayama AM, Tanaka H, Stohlmeyer MM, Woiwode TF, Wandless TJ. The enantioselective synthesis of phomopsin B Angewandte Chemie - International Edition. 46: 8157-8159. PMID 17886312 DOI: 10.1002/anie.200702537  1
2007 Maynard-Smith LA, Chen LC, Banaszynski LA, Ooi AG, Wandless TJ. A directed approach for engineering conditional protein stability using biologically silent small molecules. The Journal of Biological Chemistry. 282: 24866-72. PMID 17603093 DOI: 10.1074/jbc.M703902200  1
2007 Stankunas K, Bayle JH, Havranek JJ, Wandless TJ, Baker D, Crabtree GR, Gestwicki JE. Rescue of degradation-prone mutants of the FK506-rapamycin binding (FRB) protein with chemical ligands. Chembiochem : a European Journal of Chemical Biology. 8: 1162-9. PMID 17525916 DOI: 10.1002/cbic.200700087  1
2007 Berdeaux R, Goebel N, Banaszynski L, Takemori H, Wandless T, Shelton GD, Montminy M. SIK1 is a class II HDAC kinase that promotes survival of skeletal myocytes. Nature Medicine. 13: 597-603. PMID 17468767 DOI: 10.1038/nm1573  1
2007 Sellmyer MA, Stankunas K, Briesewitz R, Crabtree GR, Wandless TJ. Engineering small molecule specificity in nearly identical cellular environments. Bioorganic & Medicinal Chemistry Letters. 17: 2703-5. PMID 17383876 DOI: 10.1016/j.bmcl.2007.03.012  1
2007 Edwards SR, Wandless TJ. The rapamycin-binding domain of the protein kinase mammalian target of rapamycin is a destabilizing domain Journal of Biological Chemistry. 282: 13395-13401. PMID 17350953 DOI: 10.1074/jbc.M700498200  1
2006 Won DH, Inoue T, Wei SP, Man LK, Byung OP, Wandless TJ, Meyer T. PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane Science. 314: 1458-1461. PMID 17095657 DOI: 10.1126/science.1134389  1
2006 Banaszynski LA, Chen LC, Maynard-Smith LA, Ooi AG, Wandless TJ. A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules. Cell. 126: 995-1004. PMID 16959577 DOI: 10.1016/j.cell.2006.07.025  1
2006 Bayle JH, Grimley JS, Stankunas K, Gestwicki JE, Wandless TJ, Crabtree GR. Rapamycin analogs with differential binding specificity permit orthogonal control of protein activity. Chemistry & Biology. 13: 99-107. PMID 16426976 DOI: 10.1016/j.chembiol.2005.10.017  1
2006 Banaszynski LA, Wandless TJ. Conditional control of protein function Chemistry and Biology. 13: 11-21. PMID 16426967 DOI: 10.1016/j.chembiol.2005.10.010  1
2005 Yee MC, Fas SC, Stohlmeyer MM, Wandless TJ, Cimprich KA. A cell-permeable, activity-based probe for protein and lipid kinases. The Journal of Biological Chemistry. 280: 29053-9. PMID 15975929 DOI: 10.1074/jbc.M504730200  1
2005 Inoue T, Heo WD, Grimley JS, Wandless TJ, Meyer T. An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways Nature Methods. 2: 415-418. PMID 15908919 DOI: 10.1038/nmeth763  1
2005 Banaszynski LA, Liu CW, Wandless TJ. Characterization of the FKBP-rapamycin-FRB ternary complex Journal of the American Chemical Society. 127: 4715-4721. PMID 15796538 DOI: 10.1021/ja043277y  1
2004 Sawayama AM, Tanaka H, Wandless TJ. Total synthesis of ustiloxin D and considerations on the origin of selectivity of the asymmetric allylic alkylation Journal of Organic Chemistry. 69: 8810-8820. PMID 15575762 DOI: 10.1021/jo048854f  1
2004 Braun PD, Wandless TJ. Quantitative Analyses of Bifunctional Molecules Biochemistry. 43: 5406-5413. PMID 15122906 DOI: 10.1021/bi035839g  1
2003 Stankunas K, Bayle JH, Gestwicki JE, Lin YM, Wandless TJ, Crabtree GR. Conditional protein alleles using knockin mice and a chemical inducer of dimerization. Molecular Cell. 12: 1615-24. PMID 14690613 DOI: 10.1016/S1097-2765(03)00491-X  1
2003 Braun PD, Barglow KT, Lin YM, Akompong T, Briesewitz R, Ray GT, Haldar K, Wandless TJ. A bifunctional molecule that displays context-dependent cellular activity. Journal of the American Chemical Society. 125: 7575-80. PMID 12812497 DOI: 10.1021/ja035176q  1
2003 Tanaka H, Sawayama AM, Wandless TJ. Enantioselective total synthesis of ustiloxin D Journal of the American Chemical Society. 125: 6864-6865. PMID 12783528 DOI: 10.1021/ja035429f  1
2001 Vogel KW, Briesewitz R, Wandless TJ, Crabtree GR. Calcineurin inhibitors and the generalization of the presenting protein strategy. Advances in Protein Chemistry. 56: 253-91. PMID 11329856 DOI: 10.1016/S0065-3233(01)56008-8  1
2000 Wandless TJ. A confederacy of bunches: Fundamentals and applications of a self- associating protein Proceedings of the National Academy of Sciences of the United States of America. 97: 6921-6923. PMID 10852948 DOI: 10.1073/pnas.110149697  1
2000 Kar AK, Braun PD, Wandless TJ. Synthesis and evaluation of daunorubicin-paclitaxel dimers. Bioorganic & Medicinal Chemistry Letters. 10: 261-4. PMID 10698449 DOI: 10.1016/S0960-894X(99)00667-8  1
2000 Rosen MK, Amos CD, Wandless TJ. Mechanistic studies of affinity modulation Journal of the American Chemical Society. 122: 11979-11982. DOI: 10.1021/ja002991m  1
2000 Tanaka H, Stohlmeyer MM, Wandless TJ, Taylor LP. Synthesis of flavonol derivatives as probes of biological processes Tetrahedron Letters. 41: 9735-9739. DOI: 10.1016/S0040-4039(00)01767-6  1
1999 Briesewitz R, Ray GT, Wandless TJ, Crabtree GR. Affinity modulation of small-molecule ligands by borrowing endogenous protein surfaces. Proceedings of the National Academy of Sciences of the United States of America. 96: 1953-8. PMID 10051576 DOI: 10.1073/pnas.96.5.1953  1
1999 Woiwode TF, Wandless TJ. Efficient synthesis of β,γ-dehydrovaline Journal of Organic Chemistry. 64: 7670-7674. DOI: 10.1021/jo990916s  1
1999 Stohlmeyer MM, Tanaka H, Wandless TJ. A stereospecific elimination to form dehydroamino acids: Synthesis of the phomopsin tripeptide side chain Journal of the American Chemical Society. 121: 6100-6101. DOI: 10.1021/ja991037q  1
1998 Woiwode TF, Rose C, Wandless TJ. A simple and efficient method for the preparation of hindered alkyl- aryl ethers Journal of Organic Chemistry. 63: 9594-9596. DOI: 10.1021/jo981647t  1
1996 Wandless TJ. SH2 domains: A question of independence Current Biology. 6: 125-127. PMID 8673454  1
1995 Pluskey S, Wandless TJ, Walsh CT, Shoelson SE. Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains. The Journal of Biological Chemistry. 270: 2897-900. PMID 7531695 DOI: 10.1074/jbc.270.7.2897  1
1994 Sugimoto S, Wandless TJ, Shoelson SE, Neel BG, Walsh CT. Activation of the SH2-containing protein tyrosine phosphatase, SH-PTP2, by phosphotyrosine-containing peptides derived from insulin receptor substrate-1. The Journal of Biological Chemistry. 269: 13614-22. PMID 7513703  1
1993 Spencer DM, Wandless TJ, Schreiber SL, Crabtree GR. Controlling signal transduction with synthetic ligands. Science (New York, N.Y.). 262: 1019-24. PMID 7694365  1
1992 Liu J, Albers MW, Wandless TJ, Luan S, Alberg DG, Belshaw PJ, Cohen P, MacKintosh C, Klee CB, Schreiber SL. Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. Biochemistry. 31: 3896-901. PMID 1373650  1
1992 Schreiber SL, Lui J, Albers MW, Rosen MK, Standaert RF, Wandless TJ, Somers PK. Molecular Recognition of Immunophilins and Immunophilin-Ligand Complexes Tetrahedron. 48: 2545-2558. DOI: 10.1016/S0040-4020(01)88520-3  1
1991 Schreiber SL, Liu J, Albers MW, Karmacharya R, Koh E, Martin PK, Rosen MK, Standaert RF, Wandless TJ. Immunophilin-ligand complexes as probes of intracellular signaling pathways. Transplantation Proceedings. 23: 2839-44. PMID 1721293  1
1991 Michnick SW, Rosen MK, Wandless TJ, Karplus M, Schreiber SL. Solution structure of FKBP, a rotamase enzyme and receptor for FK506 and rapamycin. Science (New York, N.Y.). 252: 836-9. PMID 1709301 DOI: 10.1126/science.1709301  1
1991 Wandless TJ, Michnick SW, Rosen MK, Karplus M, Schreiber SL. FK506 and rapamycin binding to FKBP: common elements in immunophilin-ligand complexation Journal of the American Chemical Society. 113: 2339-2341. DOI: 10.1021/ja00006a083  0.72
1991 Rosen MK, Michnick SW, Wandless TJ, Schreiber SL. Study of receptor-ligand interactions through receptor labeling and isotope-edited NMR Journal of Organic Chemistry. 56: 6262-6264.  1
1991 Somers PK, Wandless TJ, Schreiber SL. Synthesis and analysis of 506BD, a high-affinity ligand for the immunophilin FKBP Journal of the American Chemical Society. 113: 8045-8056.  1
1991 Wandless TJ, Michnick SW, Rosen MK, Karplus M, Schreiber SL. FK506 and Rapamycin Binding to FKBP: Common Elements in Immunophilin-Ligand Complexation Journal of the American Chemical Society. 113: 2339-2341.  1
1990 Bierer BE, Somers PK, Wandless TJ, Burakoff SJ, Schreiber SL. Probing immunosuppressant action with a nonnatural immunophilin ligand. Science (New York, N.Y.). 250: 556-9. PMID 1700475  1
1990 Doyle MP, Bagheri V, Wandless TJ, Harn NK, Brinker DA, Eagle CT, Loh KL. Exceptionally high trans (anti) stereoselectivity in catalytic cyclopropanation reactions Journal of the American Chemical Society. 112: 1906-1912.  1
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