Ron A. Laskey - Publications

University of Cambridge, Hutchison/MRC Research Centre 
Nuclear transport, mammalian DNA replication

146 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Wickramasinghe VO, Laskey RA. Control of mammalian gene expression by selective mRNA export Nature Reviews Molecular Cell Biology. 16: 431-442. DOI: 10.1038/nrm4010  1
2014 Wickramasinghe VO, Andrews R, Ellis P, Langford C, Gurdon JB, Stewart M, Venkitaraman AR, Laskey RA. Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP. Nucleic Acids Research. 42: 5059-71. PMID 24510098 DOI: 10.1093/nar/gku095  1
2014 Jackson AP, Laskey RA, Coleman N. Replication proteins and human disease Cold Spring Harbor Perspectives in Biology. 6. PMID 23881941 DOI: 10.1101/cshperspect.a013060  1
2014 Laskey R. Monoclonal antibodies and their exploitation Biochemist. 36: 26-27.  1
2012 Poole E, Bain M, Teague L, Takei Y, Laskey R, Sinclair J. The Cellular Protein MCM3AP Is Required for Inhibition of Cellular DNA Synthesis by the IE86 Protein of Human Cytomegalovirus Plos One. 7. PMID 23094019 DOI: 10.1371/journal.pone.0045686  1
2012 Saeb-Parsy K, Wilson A, Scarpini C, Corcoran M, Chilcott S, McKean M, Thottakam B, Rai B, Nabi G, Rana D, Perera M, Stewart K, Laskey RA, Neal DE, Coleman N. Diagnosis of bladder cancer by immunocytochemical detection of minichromosome maintenance protein-2 in cells retrieved from urine. British Journal of Cancer. 107: 1384-91. PMID 22968648 DOI: 10.1038/bjc.2012.381  1
2012 Yang VS, Carter SA, Ng Y, Hyland SJ, Tachibana-Konwalski K, Fisher RA, Sebire NJ, Seckl MJ, Pedersen RA, Laskey RA, Gonzalez MA. Distinct activities of the anaphase-promoting complex/cyclosome (APC/C) in mouse embryonic cells. Cell Cycle (Georgetown, Tex.). 11: 846-55. PMID 22333576 DOI: 10.4161/cc.11.5.19251  1
2011 Yang VS, Carter SA, Hyland SJ, Tachibana-Konwalski K, Laskey RA, Gonzalez MA. Geminin Escapes degradation in G1 of mouse pluripotent cells and mediates the expression of Oct4, Sox2, and Nanog Current Biology. 21: 692-699. PMID 21497086 DOI: 10.1016/j.cub.2011.03.026  1
2011 Wickramasinghe VO, McMurtrie PI, Marr J, Amagase Y, Main S, Mills AD, Laskey RA, Takei Y. MCM3AP is transcribed from a promoter within an intron of the overlapping gene for GANP. Journal of Molecular Biology. 406: 355-61. PMID 21195085 DOI: 10.1016/j.jmb.2010.12.035  1
2011 Takei Y, Laskey R. Intracellular and intercellular cross talk between NGF and TNF Advances in Experimental Medicine and Biology. 691: 559-565. PMID 21153361 DOI: 10.1007/978-1-4419-6612-4_58  1
2010 Wickramasinghe VO, Stewart M, Laskey RA. GANP enhances the efficiency of mRNA nuclear export in mammalian cells Nucleus. 1. PMID 21326821  1
2010 Wickramasinghe VO, McMurtrie PI, Mills AD, Takei Y, Penrhyn-Lowe S, Amagase Y, Main S, Marr J, Stewart M, Laskey RA. mRNA export from mammalian cell nuclei is dependent on GANP. Current Biology : Cb. 20: 25-31. PMID 20005110 DOI: 10.1016/j.cub.2009.10.078  1
2009 Coleman N, Laskey RA. Minichromosome maintenance proteins in cancer screening European Journal of Cancer. 45: 416-417. PMID 19775653 DOI: 10.1016/S0959-8049(09)70071-1  1
2009 White V, Scarpini C, Barbosa-Morais NL, Ikelle E, Carter S, Laskey RA, Miller R, Coleman N. Isolation of stool-derived mucus provides a high yield of colonocytes suitable for early detection of colorectal carcinoma Cancer Epidemiology Biomarkers and Prevention. 18: 2006-2013. PMID 19589912 DOI: 10.1158/1055-9965.EPI-08-1145  1
2008 Scarpini C, White V, Muralidhar B, Patterson A, Hickey N, Singh N, Mullerat J, Winslet M, Davies RJ, Phillips ML, Stacey P, Laskey RA, Miller R, Nathan M, Coleman N. Improved screening for anal neoplasia by immunocytochemical detection of minichromosome maintenance proteins Cancer Epidemiology Biomarkers and Prevention. 17: 2855-2864. PMID 18843031 DOI: 10.1158/1055-9965.EPI-08-0288  1
2008 Takei Y, Laskey R. Interpreting crosstalk between TNF-α and NGF: potential implications for disease Trends in Molecular Medicine. 14: 381-388. PMID 18693138 DOI: 10.1016/j.molmed.2008.07.002  1
2008 Takei Y, Laskey R. Tumor necrosis factor α regulates responses to nerve growth factor, promoting neural cell survival but suppressing differentiation of neuroblastoma cells Molecular Biology of the Cell. 19: 855-864. PMID 18094051 DOI: 10.1091/mbc.E07-06-0624  1
2007 Ahmed AA, Mills AD, Ibrahim AE, Temple J, Blenkiron C, Vias M, Massie CE, Iyer NG, McGeoch A, Crawford R, Nicke B, Downward J, Swanton C, Bell SD, Earl HM, ... Laskey RA, et al. The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel. Cancer Cell. 12: 514-27. PMID 18068629 DOI: 10.1016/j.ccr.2007.11.014  1
2007 Mukherjee G, Muralidhar B, Bafna UD, Laskey RA, Coleman N. MCM immunocytochemistry as a first line cervical screening test in developing countries: A prospective cohort study in a regional cancer centre in India British Journal of Cancer. 96: 1107-1111. PMID 17342084 DOI: 10.1038/sj.bjc.6603679  1
2007 Chang CL, Lao-Sirieix P, Save V, De La Cueva Mendez G, Laskey R, Fitzgerald RC. Retinoic acid-induced glandular differentiation of the oesophagus. Gut. 56: 906-17. PMID 17185354 DOI: 10.1136/gut.2006.097915  1
2006 Gonzalez MA, Tachibana KEK, Adams DJ, Van Der Weyden L, Hemberger M, Coleman N, Bradley A, Laskey RA. Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development Genes and Development. 20: 1880-1884. PMID 16847348 DOI: 10.1101/gad.379706  1
2006 Scott IS, Odell E, Chatrath P, Morris LS, Davies RJ, Vowler SL, Laskey RA, Coleman N. A minimally invasive immunocytochemical approach to early detection of oral squamous cell carcinoma and dysplasia. British Journal of Cancer. 94: 1170-5. PMID 16622441 DOI: 10.1038/sj.bjc.6603066  1
2005 Laskey R. Solving mysteries of DNA replication and frog cloning Cell. 123: 760-762. PMID 16325570 DOI: 10.1016/j.cell.2005.11.008  1
2005 Tachibana KK, Gonzalez MA, Guarguaglini G, Nigg EA, Laskey RA. Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects Embo Reports. 6: 1052-1057. PMID 16179947 DOI: 10.1038/sj.embor.7400527  1
2005 Laskey R. The Croonian Lecture 2001 hunting the antisocial cancer cell: MCM proteins and their exploitation Philosophical Transactions of the Royal Society B: Biological Sciences. 360: 1119-1132. PMID 16147513 DOI: 10.1098/rstb.2005.1656  1
2005 McGeoch AT, Trakselis MA, Laskey RA, Bell SD. Organization of the archaeal MCM complex on DNA and implications for the helicase mechanism Nature Structural and Molecular Biology. 12: 756-762. PMID 16116441 DOI: 10.1038/nsmb974  1
2005 Gonzalez MA, Tachibana KEK, Laskey RA, Coleman N. Control of DNA replication and its potential clinical exploitation Nature Reviews Cancer. 5: 135-141. PMID 15660109 DOI: 10.1038/nrc1548  1
2004 Gonzalez MA, Tachibana KK, Chin SF, Callagy G, Madine MA, Vowler SL, Pinder SE, Laskey RA, Coleman N. Geminin predicts adverse clinical outcome in breast cancer by reflecting cell-cycle progression Journal of Pathology. 204: 121-130. PMID 15376260 DOI: 10.1002/path.1625  1
2003 Gonzalez MA, Pinder SE, Callagy G, Vowler SL, Morris LS, Bird K, Bell JA, Laskey RA, Coleman N. Minichromosome maintenance protein 2 is a strong independent prognostic marker in breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 4306-13. PMID 14645419 DOI: 10.1200/JCO.2003.04.121  1
2003 Scott IS, Morris LS, Bird K, Davies RJ, Vowler SL, Rushbrook SM, Marshall AE, Laskey RA, Miller R, Arends MJ, Coleman N. A novel immunohistochemical method to estimate cell-cycle phase distribution in archival tissue: implications for the prediction of outcome in colorectal cancer. The Journal of Pathology. 201: 187-97. PMID 14517835 DOI: 10.1002/path.1444  1
2003 Chatrath P, Scott IS, Morris LS, Davies RJ, Rushbrook SM, Bird K, Vowler SL, Grant JW, Saeed IT, Howard D, Laskey RA, Coleman N. Aberrant expression of minichromosome maintenance protein-2 and Ki67 in laryngeal squamous epithelial lesions. British Journal of Cancer. 89: 1048-54. PMID 12966424 DOI: 10.1038/sj.bjc.6601234  1
2003 Baldwin P, Laskey R, Coleman N. Translational approaches to improving cervical screening Nature Reviews Cancer. 3: 217-226. PMID 12612656 DOI: 10.1038/nrc1010  1
2003 Davidson EJ, Morris LS, Scott IS, Rushbrook SM, Bird K, Laskey RA, Wilson GE, Kitchener HC, Coleman N, Stern PL. Minichromosome maintenance (Mcm) proteins, cyclin B1 and D1, phosphohistone H3 and in situ DNA replication for functional analysis of vulval intraepithelial neoplasia. British Journal of Cancer. 88: 257-62. PMID 12610511 DOI: 10.1038/sj.bjc.6600729  1
2003 Clay-Farrace L, Pelizon C, Santamaria D, Pines J, Laskey RA. Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1 Embo Journal. 22: 704-712. PMID 12554670 DOI: 10.1093/emboj/cdg046  1
2003 Laskey RA, Madine MA. A rotary pumping model for helicase function of MCM proteins at a distance from replication forks Embo Reports. 4: 26-30. PMID 12524516 DOI: 10.1038/sj.embor.embor706  1
2003 De la Cueva-Méndez G, Mills AD, Clay-Farrace L, Diaz-Orejas R, Laskey RA. Regulatable killing of eukaryotic cells by the prokaryotic proteins Kid and Kis Embo Journal. 22: 246-251. PMID 12514130 DOI: 10.1093/emboj/cdg026  1
2002 Takei Y, Assenberg M, Tsujimoto G, Laskey R. The MCM3 acetylase MCM3AP inhibits initiation, but not elongation, of DNA replication via interaction with MCM3 Journal of Biological Chemistry. 277: 43121-43125. PMID 12226073 DOI: 10.1074/jbc.C200442200  1
2002 Pelizon C, d'Adda di Fagagna F, Farrace L, Laskey RA. Human replication protein Cdc6 is selectively cleaved by caspase 3 during apoptosis Embo Reports. 3: 780-784. PMID 12151338 DOI: 10.1093/embo-reports/kvf161  1
2002 Coverley D, Laman H, Laskey RA. Distinct roles for cyclins E and A during DNA replication complex assembly and activation Nature Cell Biology. 4: 523-528. PMID 12080347 DOI: 10.1038/ncb813  1
2002 Davies RJ, Freeman A, Morris LS, Bingham S, Dilworth S, Scott I, Laskey RA, Miller R, Coleman N. Analysis of minichromosome maintenance proteins as a novel method for detection of colorectal cancer in stool. Lancet. 359: 1917-9. PMID 12057556 DOI: 10.1016/S0140-6736(02)08739-1  1
2002 Hunt DP, Freeman A, Morris LS, Burnet NG, Bird K, Davies TW, Laskey RA, Coleman N. Early recurrence of benign meningioma correlates with expression of mini-chromosome maintenance-2 protein. British Journal of Neurosurgery. 16: 10-5. PMID 11928726 DOI: 10.1080/02688690120114174  1
2001 Takei Y, Swietlik M, Tanoue A, Tsujimoto G, Kouzarides T, Laskey R. MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3 Embo Reports. 2: 119-123. PMID 11258703 DOI: 10.1093/embo-reports/kve026  1
2001 Madine M, Laskey R. Geminin bans replication licence Nature Cell Biology. 3: E49-E50. PMID 11175762 DOI: 10.1038/35055158  1
2000 Pelizon C, Madine MA, Romanowski P, Laskey RA. Unphosphorylatable mutants of Cdc6 disrupt its nuclear export but still support DNA replication once per cell cycle Genes and Development. 14: 2526-2533. PMID 11018019 DOI: 10.1101/gad.176300  1
2000 Coverley D, Pelizon C, Trewick S, Laskey RA. Chromatin-bound Cdc6 persists in S and G2 phases in human cells, while soluble Cdc6 is destroyed in a cyclin A-cdk2 dependent process Journal of Cell Science. 113: 1929-1938. PMID 10806104  1
2000 Madine MA, Swietlik M, Pelizon C, Romanowski P, Mills AD, Laskey RA. The roles of the MCM, ORC, and Cdc6 proteins in determining the replication competence of chromatin in quiescent cells Journal of Structural Biology. 129: 198-210. PMID 10806069 DOI: 10.1006/jsbi.2000.4218  1
2000 Mills AD, Coleman N, Morris LS, Laskey RA. Detection of S-phase cells in tissue sections by in situ DNA replication. Nature Cell Biology. 2: 244-5. PMID 10783244 DOI: 10.1038/35008670  1
2000 Philpott A, Krude T, Laskey RA. Nuclear chaperones. Seminars in Cell & Developmental Biology. 11: 7-14. PMID 10736259 DOI: 10.1006/scdb.1999.0346  1
2000 Romanowski P, Marr J, Madine MA, Rowles A, Blow JJ, Gautier J, Laskey RA. Interaction of Xenopus Cdc2·cyclin A1 with the origin recognition complex Journal of Biological Chemistry. 275: 4239-4243. PMID 10660590 DOI: 10.1074/jbc.275.6.4239  1
1999 Stoeber K, Halsall I, Freeman A, Swinn R, Doble A, Morris L, Coleman N, Bullock N, Laskey RA, Hales CN, Williams GH. Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine Lancet. 354: 1524-1525. PMID 10551502 DOI: 10.1016/S0140-6736(99)04265-8  1
1999 Freeman A, Morris LS, Mills AD, Stoeber K, Laskey RA, Williams GH, Coleman N. Minichromosome maintenance proteins as biological markers of dysplasia and malignancy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 5: 2121-32. PMID 10473096  1
1999 Yankulov K, Todorov I, Romanowski P, Licatalosi D, Cilli K, McCracken S, Laskey R, Bentley DL. MCM proteins are associated with RNA polymerase II holoenzyme. Molecular and Cellular Biology. 19: 6154-63. PMID 10454562  1
1998 Laskey RA. Regulatory roles of the nuclear membrane Biochemical Society Transactions. 26: 561-567. PMID 10047782  1
1998 Dingwall C, Laskey RA. Nuclear import: A tale of two sites Current Biology. 8: R922-R924. PMID 9889096  1
1998 Stoeber K, Mills AD, Kubota Y, Krude T, Romanowski P, Marheineke K, Laskey RA, Williams GH. Cdc6 protein causes premature entry into S phase in a mammalian cell-free system Embo Journal. 17: 7219-7229. PMID 9857179 DOI: 10.1093/emboj/17.24.7219  1
1998 Williams GH, Romanowski P, Morris L, Madine M, Mills AD, Stoeber K, Marr J, Laskey RA, Coleman N. Improved cervical smear assessment using antibodies against proteins that regulate DNA replication Proceedings of the National Academy of Sciences of the United States of America. 95: 14932-14937. PMID 9843993 DOI: 10.1073/pnas.95.25.14932  1
1998 Ritzi M, Baack M, Musahl C, Romanowski P, Laskey RA, Knippers R. Human minichromosome maintenance proteins and human origin recognition complex 2 protein on chromatin Journal of Biological Chemistry. 273: 24543-24549. PMID 9733749 DOI: 10.1074/jbc.273.38.24543  1
1998 Coverley D, Wilkinson HR, Madine MA, Mills AD, Laskey RA. Protein kinase inhibition in G2 causes mammalian Mcm proteins to reassociate with chromatin and restores ability to replicate Experimental Cell Research. 238: 63-69. PMID 9457057 DOI: 10.1006/excr.1997.3829  1
1997 Crevel G, Huikeshoven H, Cotterill S, Simon M, Wall J, Philpott A, Laskey RA, McConnell M, Fisher PA, Berrios M. Molecular and cellular characterization of CRP1, a Drosophila chromatin decondensation protein. Journal of Structural Biology. 118: 9-22. PMID 9087911 DOI: 10.1006/jsbi.1996.3836  1
1997 Krude T, Jackman M, Pines J, Laskey RA. Cyclin/Cdk-dependent initiation of DNA replication in a human cell-free system Cell. 88: 109-119. PMID 9019396  1
1996 Laskey RA, Görlich D, Madine MA, Makkerh JP, Romanowski P. Regulatory roles of the nuclear envelope. Experimental Cell Research. 229: 204-11. PMID 8986599 DOI: 10.1006/excr.1996.0361  1
1996 Romanowski P, Madine MA, Rowles A, Blow JJ, Laskey RA. The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin Current Biology. 6: 1416-1425. PMID 8939603  1
1996 Görlich D, Kraft R, Kostka S, Vogel F, Hartmann E, Laskey RA, Mattaj IW, Izaurralde E. Importin provides a link between nuclear protein import and U snRNA export. Cell. 87: 21-32. PMID 8858145 DOI: 10.1016/S0092-8674(00)81319-7  1
1996 Krude T, Musahl C, Laskey RA, Knippers R. Human replication proteins hCdc21, hCdc46 and P1Mcm3 bind chromatin uniformly before S-phase and are displaced locally during DNA replication Journal of Cell Science. 109: 309-318. PMID 8838654  1
1996 Romanowski P, Madine MA, Laskey RA. XMCM7, a novel member of the Xenopus MCM family, interacts with XMCM3 and colocalizes with it throughout replication Proceedings of the National Academy of Sciences of the United States of America. 93: 10189-10194. PMID 8816774 DOI: 10.1073/pnas.93.19.10189  1
1996 Makkerh JPS, Dingwall C, Laskey RA. Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids Current Biology. 6: 1025-1027. PMID 8805337 DOI: 10.1016/S0960-9822(02)00648-6  1
1996 Leno GH, Mills AD, Philpott A, Laskey RA. Hyperphosphorylation of nucleoplasmin facilitates Xenopus sperm decondensation at fertilization. The Journal of Biological Chemistry. 271: 7253-6. PMID 8631735 DOI: 10.1074/jbc.271.13.7253  1
1996 Görlich D, Henklein P, Laskey RA, Hartmann E. A 41 amino acid motif in importin-alpha confers binding to importin-beta and hence transit into the nucleus. The Embo Journal. 15: 1810-7. PMID 8617226  1
1996 Laskey RA, Krude T, Madine M, Coverley D, Romanowski P, Mills AD. Coupling dna replication to the cell cycle Biochemical Society Transactions. 24: 507S.  1
1995 Görlich D, Laskey RA. Roles of importin in nuclear protein import. Cold Spring Harbor Symposia On Quantitative Biology. 60: 695-9. PMID 8824444  1
1995 Madine MA, Khoo CY, Mills AD, Musahl C, Laskey RA. The nuclear envelope prevents reinitiation of replication by regulating the binding of MCM3 to chromatin in Xenopus egg extracts Current Biology. 5: 1270-1279. PMID 8574584 DOI: 10.1016/S0960-9822(95)00253-3  1
1995 Madine MA, Khoo CY, Mills AD, Laskey RA. MCM3 complex required for cell cycle regulation of DNA replication in vertebrate cells Nature. 375: 421-424. PMID 7760938  1
1995 Görlich D, Vogel F, Mills AD, Hartmann E, Laskey RA. Distinct functions for the two importin subunits in nuclear protein import. Nature. 377: 246-8. PMID 7675110 DOI: 10.1038/377246a0  1
1995 Görlich D, Kostka S, Kraft R, Dingwall C, Laskey RA, Hartmann E, Prehn S. Two different subunits of importin cooperate to recognize nuclear localization signals and bind them to the nuclear envelope. Current Biology : Cb. 5: 383-92. PMID 7627554 DOI: 10.1016/S0960-9822(95)00079-0  1
1994 Görlich D, Prehn S, Laskey RA, Hartmann E. Isolation of a protein that is essential for the first step of nuclear protein import. Cell. 79: 767-78. PMID 8001116 DOI: 10.1016/0092-8674(94)90067-1  1
1994 Coverley D, Laskey RA. Regulation of eukaryotic DNA replication Annual Review of Biochemistry. 63: 745-776. PMID 7979254  1
1993 Sleeman JP, Laskey RA. Xenopus c-ski contains a novel coiled-coil protein domain, and is maternally expressed during development Oncogene. 8: 67-77. PMID 8423997  1
1993 Laskey RA, Dingwall C. Nuclear shuttling: The default pathway for nuclear proteins? Cell. 74: 585-586. PMID 8358787 DOI: 10.1016/0092-8674(93)90505-K  1
1993 Coverley D, Downes CS, Romanowski P, Laskey RA. Reversible effects of nuclear membrane permeabilization on DNA replication: Evidence for a positive licensing factor Journal of Cell Biology. 122: 985-992. PMID 8354698  1
1993 Laskey RA, Mills AD, Philpott A, Leno GH, Dilworth SM, Dingwall C. The role of nucleoplasmin in chromatin assembly and disassembly. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 339: 263-9; discussion 26. PMID 8098530 DOI: 10.1098/rstb.1993.0024  1
1992 Leno GH, Downes CS, Laskey RA. The nuclear membrane prevents replication of human G2 nuclei but not G1 nuclei in Xenopus egg extract Cell. 69: 151-158. PMID 1555238 DOI: 10.1016/0092-8674(92)90126-W  1
1992 Sleeman AM, Leno GH, Mills AD, Fairman MP, Laskey RA. Patterns of DNA replication in Drosophila polytene nuclei replicating in Xenopus egg and oocyte extracts Journal of Cell Science. 101: 509-515. PMID 1522141  1
1992 Dingwall C, Laskey RA. Introduction: The nuclear envelope Seminars in Cell Biology. 3: 221-223. DOI: 10.1016/1043-4682(92)90023-O  1
1991 Philpott A, Leno GH, Laskey RA. Sperm decondensation in Xenopus egg cytoplasm is mediated by nucleoplasmin. Cell. 65: 569-78. PMID 2032284 DOI: 10.1016/0092-8674(91)90089-H  1
1991 Leno GH, Laskey RA. The nuclear membrane determines the timing of DNA replication in Xenopus egg extracts Journal of Cell Biology. 112: 557-566. PMID 1993731  1
1991 Robbins J, Dilwortht SM, Laskey RA, Dingwall C. Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence Cell. 64: 615-623. PMID 1991323 DOI: 10.1016/0092-8674(91)90245-T  1
1991 Cox LS, Laskey RA. DNA replication occurs at discrete sites in pseudonuclei assembled from purified DNA in vitro Cell. 66: 271-275. PMID 1830242 DOI: 10.1016/0092-8674(91)90617-8  1
1991 Laskey RA, Cox LS, Leno GH, Philpott A, Mills AD, Sleeman AM. Control of DNA replication in reconstituted nuclei. Cold Spring Harbor Symposia On Quantitative Biology. 56: 347-52. PMID 1819495  1
1991 Leno GH, Laskey RA. Chapter 29 DNA Replication in Cell-Free Extracts from Xenopus laevis Methods in Cell Biology. 36: 561-574,574a,574b,57. PMID 1811152 DOI: 10.1016/S0091-679X(08)60297-6  1
1991 Dingwall C, Laskey RA. Nuclear targeting sequences - a consensus? Trends in Biochemical Sciences. 16: 478-481. PMID 1664152 DOI: 10.1016/0968-0004(91)90184-W  1
1991 Laskey R, Scott MP. Editorial Current Opinion in Genetics and Development. 1: 1.  1
1990 Laskey RA, Leno GH. Assembly of the cell nucleus Trends in Genetics. 6: 406-409. PMID 2087783 DOI: 10.1016/0168-9525(90)90301-L  1
1990 Dingwall C, Laskey RA. Nucleoplasmin: the archetypal molecular chaperone. Seminars in Cell Biology. 1: 11-17. PMID 1983266  1
1989 Rhodes D, Laskey RA. Assembly of nucleosomes and chromatin in vitro Methods in Enzymology. 170: 575-585. PMID 2770552  1
1989 Laskey RA, Fairman MP, Blow JJ. S phase of the cell cycle Science. 246: 609-614. PMID 2683076  1
1989 Blow JJ, Sheehan MA, Watson JV, Laskey RA. Nuclear structure and the control of DNA replication in the Xenopus embryo Journal of Cell Science. 94: 183-195. PMID 2635705  1
1989 Mills AD, Blow JJ, White JG, Amos WB, Wilcock D, Laskey RA. Replication occurs at discrete foci spaced throughout nuclei replicating in vitro Journal of Cell Science. 94: 471-477. PMID 2632579  1
1989 Laskey RA, Gerace L. Nucleus and gene expression Current Opinion in Cell Biology. 1: 433-434.  1
1988 Blow JJ, Laskey RA. A role for the nuclear envelope in controlling DNA replication within the cell cycle Nature. 332: 546-548. PMID 3357511  1
1988 Sheehan MA, Mills AD, Sleeman AM, Laskey RA, Blow JJ. Steps in the assembly of replication-competent nuclei in a cell-free system from Xenopus eggs Journal of Cell Biology. 106: 1-12. PMID 3339085  1
1988 Richardson WD, Mills AD, Dilworth SM, Laskey RA, Dingwall C. Nuclear protein migration involves two steps: rapid binding at the nuclear envelope followed by slower translocation through nuclear pores. Cell. 52: 655-64. PMID 3125984 DOI: 10.1016/0092-8674(88)90403-5  1
1987 Dilworth SM, Black SJ, Laskey RA. Two complexes that contain histones are required for nucleosome assembly in vitro: Role of nucleoplasmin and N1 in Xenopus egg extracts Cell. 51: 1009-1018. PMID 3690659 DOI: 10.1016/0092-8674(87)90587-3  1
1987 Laskey RA. The cell nucleus British Medical Journal. 295: 1121-1123. PMID 3120908  1
1987 Blow JJ, Dilworth SM, Dingwall C, Mills AD, Laskey RA. Chromosome replication in cell-free systems from Xenopus eggs. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 317: 483-494. PMID 2894683  1
1987 Dingwall C, Dilworth SM, Black SJ, Kearsey SE, Cox LS, Laskey RA. Nucleoplasmin cDNA sequence reveals polyglutamic acid tracts and a cluster of sequences homologous to putative nuclear localization signals. Embo Journal. 6: 69-74. PMID 2884102  1
1986 Blow JJ, Laskey RA. Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs Cell. 47: 577-587. PMID 3779837 DOI: 10.1016/0092-8674(86)90622-7  1
1986 Dingwall C, Laskey RA. Protein import into the cell nucleus. Annual Review of Cell Biology. 2: 367-390. PMID 3548772  1
1986 Laskey RA. Prospects for reassembling the cell nucleus. Journal of Cell Science. Supplement. 4: 1-9. PMID 3528187  1
1985 Laskey RA, Kearsey SE, Mechali M, Dingwall C, Mills AD, Dilworth SM, Kleinschmidt J. Chromosome replication in early Xenopus embryos. Cold Spring Harbor Symposia On Quantitative Biology. 50: 657-63. PMID 3868500  1
1985 Laskey RA. Chromosome replication in early development of Xenopus laevis. Journal of Embryology and Experimental Morphology. 89: 285-96. PMID 3831215  1
1983 Laskey RA, Harland RM, Méchali M. Induction of chromosome replication during maturation of amphibian oocytes. Ciba Foundation Symposium. 98: 25-43. PMID 6557009  1
1983 Méchali M, Méchali F, Laskey RA. Tumor promoter TPA increases initiation of replication on DNA injected into xenopus eggs. Cell. 35: 63-9. PMID 6226366 DOI: 10.1016/0092-8674(83)90208-8  1
1983 Laskey RA. Phosphorylation of nuclear proteins. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 302: 143-50. PMID 6137002  1
1983 Laskey RA, Mechali M. Accelerated chromatin replication in embryonic cells Cell Biology International Reports. 7: 547-548. DOI: 10.1016/0309-1651(83)90171-6  1
1982 Gurdon JB, Dingwall C, Laskey RA, Korn LJ. Developmental inactivity of 5S RNA genes persists when chromosomes are cut between genes. Nature. 299: 652-3. PMID 6889684 DOI: 10.1038/299652a0  1
1982 Dingwall C, Sharnick SV, Laskey RA. A polypeptide domain that specifies migration of nucleoplasmin into the nucleus. Cell. 30: 449-58. PMID 6814762 DOI: 10.1016/0092-8674(82)90242-2  1
1982 Laskey RA, Harland RM. Replication origins in the Xenopus egg. Cell. 31: 503. PMID 6297769  1
1981 Dingwall C, Lomonossoff GP, Laskey RA. High sequence specificity of micrococcal nuclease. Nucleic Acids Research. 9: 2659-73. PMID 6269057 DOI: 10.1093/nar/9.12.2659  1
1981 Laskey RA. Molecular mechanisms of chromatin assembly. Biochemical Society Transactions. 9: 263-70. PMID 6266896  1
1981 Laskey RA, Harland RM. Replication origins in the eucaryotic chromosome. Cell. 24: 283-4. PMID 6263494  1
1980 Mills AD, Laskey RA, Black P, De Robertis EM. An acidic protein which assembles nucleosomes in vitro is the most abundant protein in Xenopus oocyte nuclei. Journal of Molecular Biology. 139: 561-8. PMID 7441745 DOI: 10.1016/0022-2836(80)90148-5  1
1980 Earnshaw WC, Honda BM, Laskey RA, Thomas JO. Assembly of nucleosomes: the reaction involving X. laevis nucleoplasmin. Cell. 21: 373-83. PMID 7407918  1
1980 Laskey RA. [45] The use of intensifying screens or organic scintillators for visualizing radioactive molecules resolved by gel electrophoresis Methods in Enzymology. 65: 363-371. PMID 7374459 DOI: 10.1016/S0076-6879(80)65047-2  1
1980 Harland RM, Laskey RA. Regulated replication of DNA microinjected into eggs of Xenopus laevis. Cell. 21: 761-71. PMID 6254667  1
1980 Laskey RA, Earnshaw WC. Nucleosome assembly. Nature. 286: 763-7. PMID 6250082 DOI: 10.1038/286763a0  1
1979 Gurdon JB, Laskey RA, De Robertis EM, Partington GA. Reprogramming of transplanted nuclei in amphibia. International Review of Cytology. Supplement. 161-78. PMID 385535  1
1978 Laskey RA, Honda BM, Mills AD, Finch JT. Nucleosomes are assembled by an acidic protein which binds histones and transfers them to DNA Nature. 275: 416-420. PMID 692721 DOI: 10.1038/275416a0  1
1978 Laskey RA, Honda BM, Mills AD, Morris NR, Wyllie AH, Mertz JE, De Roberts EM, Gurdon JB. Chromatin assembly and transcription in eggs and oocytes of Xenopus laevis. Cold Spring Harbor Symposia On Quantitative Biology. 42: 171-8. PMID 209936  1
1978 Wyllie AH, Laskey RA, Finch J, Gurdon JB. Selective DNA conservation and chromatin assembly after injection of SV40 DNA into Xenopus oocytes. Developmental Biology. 64: 178-88. PMID 207607 DOI: 10.1016/0012-1606(78)90069-6  1
1977 Laskey RA, Mills AD. Enhanced autoradiographic detection of 32P and 125I using intensifying screens and hypersensitized film Febs Letters. 82: 314-316. PMID 913604 DOI: 10.1016/0014-5793(77)80609-1  1
1977 Laskey RA, Mills AD, Gurdon JB, Partington GA. Protein synthesis in oocytes of Xenopus laevis is not regulated by the supply of messenger RNA. Cell. 11: 345-51. PMID 560911 DOI: 10.1016/0092-8674(77)90051-4  1
1977 de Robertis EM, Gurdon JB, Partington GA, Mertz JE, Laskey RA. Injected amphibian oocytes: a living test tube for the study of eukaryotic gene transcription? Biochemical Society Symposium. 181-91. PMID 339919  1
1977 Laskey RA, Mills AD, Morris NR. Assembly of SV40 chromatin in a cell-free system from Xenopus eggs Cell. 10: 237-243. PMID 189936 DOI: 10.1016/0092-8674(77)90217-3  1
1977 De Robertis EM, Laskey RA, Gurdon JB. Injected living cells as a biochemical test tube Trends in Biochemical Sciences. 2: N250-N251,N253. DOI: 10.1016/0968-0004(77)90206-7  1
1975 Reeves OR, Laskey RA. In vitro differentiation of a homogeneous cell population: the epidermis of Xenopus laevis Journal of Embryology and Experimental Morphology. 34: 75-92. PMID 1237533  1
1975 Laskey RA, Mills AD. Quantitative film detection of 3H and 14C in polyacrylamide gels by fluorography European Journal of Biochemistry. 56: 335-341. PMID 1175627  1
1975 Gurdon JB, Laskey RA, Reeves OR. The developmental capacity of nuclei transplanted from keratinized skin cells of adult frogs. Journal of Embryology and Experimental Morphology. 34: 93-112. PMID 1102625  1
1974 Bonner WM, Laskey RA. A film detection method for tritium labelled proteins and nucleic acids in polyacrylamide gels European Journal of Biochemistry. 46: 83-88. PMID 4850204  1
1974 Laskey RA, Gurdon JB. The translation of viral RNAs in frog oocytes. HäMatologie Und Bluttransfusion. 14: 272-4. PMID 4615046  1
1973 Laskey RA, Gerhart JC, Knowland JS. Inhibition of ribosomal RNA synthesis in neurula cells by extracts from blastulae of Xenopus laevis. Developmental Biology. 33: 241-8. PMID 4363801 DOI: 10.1016/0012-1606(73)90134-6  1
1973 Laskey RA, Gurdon JB. Induction of polyoma DNA synthesis by injection into frog-egg cytoplasm. European Journal of Biochemistry / Febs. 37: 467-71. PMID 4359989  1
1972 Laskey RA, Gurdon JB, Crawford LV. Translation of encephalomyocarditis viral RNA in oocytes of Xenopus laevis. Proceedings of the National Academy of Sciences of the United States of America. 69: 3665-9. PMID 4345506  1
1970 Gurdon JB, Laskey RA. The transplantation of nuclei from single cultured cells into enucleate frogs' eggs. Journal of Embryology and Experimental Morphology. 24: 227-48. PMID 5531072  1
1970 Laskey RA, Gurdon JB. Genetic content of adult somatic cells tested by nuclear transplantation from cultured cells. Nature. 228: 1332-4. PMID 5530658 DOI: 10.1038/2281332a0  1
1970 Gurdon JB, Laskey RA. Methods of transplanting nuclei from single cultured cells to unfertilized frogs' eggs. Journal of Embryology and Experimental Morphology. 24: 249-55. PMID 4923666  1
1970 Laskey RA. The use of antibiotics in the preparation of amphibian cell cultures from highly contaminated material Journal of Cell Science. 7: 653-659. PMID 4321684  1
Show low-probability matches.