Ali Shilatifard - Publications

Affiliations: 
Saint Louis University, St. Louis, MO, United States 
Area:
Molecular Biology, Biochemistry, Cell Biology

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Piunti A, Smith ER, Morgan MAJ, Ugarenko M, Khaltyan N, Helmin KA, Ryan CA, Murray DC, Rickels RA, Yilmaz BD, Rendleman EJ, Savas JN, Singer BD, Bulun SE, Shilatifard A. CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism. Science Advances. 5: eaax2887. PMID 31281901 DOI: 10.1126/sciadv.aax2887  0.4
2019 Chung CY, Berson A, Kennerdell JR, Sartoris A, Unger T, Porta S, Kim HJ, Smith ER, Shilatifard A, Van Deerlin V, Lee VM, Chen-Plotkin A, Bonini NM. Author Correction: Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity. Nature Communications. 10: 555. PMID 30696825 DOI: 10.1038/s41467-019-08562-x  0.4
2018 Wang L, Ozark PA, Smith ER, Zhao Z, Marshall SA, Rendleman EJ, Piunti A, Ryan C, Whelan AL, Helmin KA, Morgan MA, Zou L, Singer BD, Shilatifard A. TET2 coactivates gene expression through demethylation of enhancers. Science Advances. 4: eaau6986. PMID 30417100 DOI: 10.1126/sciadv.aau6986  0.4
2018 Chung CY, Berson A, Kennerdell JR, Sartoris A, Unger T, Porta S, Kim HJ, Smith ER, Shilatifard A, Van Deerlin V, Lee VM, Chen-Plotkin A, Bonini NM. Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity. Nature Communications. 9: 4406. PMID 30353006 DOI: 10.1038/s41467-018-06543-0  0.4
2018 Liang K, Smith ER, Aoi Y, Stoltz KL, Katagi H, Woodfin AR, Rendleman EJ, Marshall SA, Murray DC, Wang L, Ozark PA, Mishra RK, Hashizume R, Schiltz GE, Shilatifard A. Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy. Cell. 175: 766-779.e17. PMID 30340042 DOI: 10.1016/j.cell.2018.09.027  0.4
2018 Hong SH, Fang S, Lu BC, Nofsinger R, Kawakami Y, Castro GL, Yin Y, Lin C, Yu RT, Downes M, Izpisúa Belmonte JC, Shilatifard A, Evans RM. Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30254164 DOI: 10.1073/pnas.1809480115  0.4
2018 Wang L, Zhao Z, Ozark PA, Fantini D, Marshall SA, Rendleman EJ, Cozzolino KA, Louis N, He X, Morgan MA, Takahashi YH, Collings CK, Smith ER, Ntziachristos P, Savas JN, ... ... Shilatifard A, et al. Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy. Nature Medicine. PMID 29785026 DOI: 10.1038/s41591-018-0034-6  0.4
2018 Chen FX, Smith ER, Shilatifard A. Born to run: control of transcription elongation by RNA polymerase II. Nature Reviews. Molecular Cell Biology. PMID 29740129 DOI: 10.1038/s41580-018-0010-5  0.4
2018 Cao K, Collings CK, Morgan MA, Marshall SA, Rendleman EJ, Ozark PA, Smith ER, Shilatifard A. An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells. Science Advances. 4: eaap8747. PMID 29404406 DOI: 10.1126/sciadv.aap8747  0.4
2017 Rickels R, Herz HM, Sze CC, Cao K, Morgan MA, Collings CK, Gause M, Takahashi YH, Wang L, Rendleman EJ, Marshall SA, Krueger A, Bartom ET, Piunti A, Smith ER, ... ... Shilatifard A, et al. Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability. Nature Genetics. PMID 28967912 DOI: 10.1038/ng.3965  0.4
2017 Chen FX, Xie P, Collings CK, Cao K, Aoi Y, Marshall SA, Rendleman EJ, Ugarenko M, Ozark PA, Zhang A, Shiekhattar R, Smith ER, Zhang MQ, Shilatifard A. PAF1 regulation of promoter-proximal pause release via enhancer activation. Science (New York, N.Y.). PMID 28860207 DOI: 10.1126/science.aan3269  0.4
2017 Hu D, Gao X, Cao K, Morgan MA, Mas G, Smith ER, Volk AG, Bartom ET, Crispino JD, Di Croce L, Shilatifard A. Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification. Molecular Cell. 65: 460-475.e6. PMID 28157506 DOI: 10.1016/j.molcel.2017.01.013  0.4
2017 Liang K, Volk AG, Haug JS, Marshall SA, Woodfin AR, Bartom ET, Gilmore JM, Florens L, Washburn MP, Sullivan KD, Espinosa JM, Cannova J, Zhang J, Smith ER, Crispino JD, ... Shilatifard A, et al. Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia. Cell. PMID 28065413 DOI: 10.1016/j.cell.2016.12.011  0.4
2016 D'Urso A, Takahashi YH, Xiong B, Marone J, Coukos R, Randise-Hinchliff C, Wang JP, Shilatifard A, Brickner JH. Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory. Elife. 5. PMID 27336723 DOI: 10.7554/eLife.16691  0.76
2016 Luo Z, Lin C, Woodfin AR, Bartom ET, Gao X, Smith ER, Shilatifard A. Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity. Genes & Development. 30: 92-101. PMID 26728555 DOI: 10.1101/gad.270413.115  0.76
2015 Liang K, Woodfin AR, Slaughter BD, Unruh JR, Box AC, Rickels RA, Gao X, Haug JS, Jaspersen SL, Shilatifard A. Mitotic Transcriptional Activation: Clearance of Actively Engaged Pol II via Transcriptional Elongation Control in Mitosis. Molecular Cell. 60: 435-45. PMID 26527278 DOI: 10.1016/j.molcel.2015.09.021  0.76
2015 Ortega-Molina A, Boss IW, Canela A, Pan H, Jiang Y, Zhao C, Jiang M, Hu D, Agirre X, Niesvizky I, Lee JE, Chen HT, Ennishi D, Scott DW, Mottok A, ... ... Shilatifard A, et al. The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development. Nature Medicine. PMID 26366710 DOI: 10.1038/nm.3943  0.76
2015 Zhu J, Sammons MA, Donahue G, Dou Z, Vedadi M, Getlik M, Barsyte-Lovejoy D, Al-awar R, Katona BW, Shilatifard A, Huang J, Hua X, Arrowsmith CH, Berger SL. Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth. Nature. 525: 206-11. PMID 26331536 DOI: 10.1038/nature15251  0.76
2015 Chen FX, Woodfin AR, Gardini A, Rickels RA, Marshall SA, Smith ER, Shiekhattar R, Shilatifard A. PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II. Cell. PMID 26279188 DOI: 10.1016/j.cell.2015.07.042  0.76
2015 De Kumar B, Parrish ME, Slaughter BD, Unruh JR, Gogol M, Seidel C, Paulson A, Li H, Gaudenz K, Peak A, McDowell W, Fleharty B, Ahn Y, Lin C, Smith E, ... Shilatifard A, et al. Analysis of dynamic changes in retinoid-induced transcription and epigenetic profiles of murine Hox clusters in ES cells. Genome Research. PMID 26025802 DOI: 10.1101/gr.184978.114  0.76
2015 Fowler T, Ghatak P, Price DH, Conaway R, Conaway J, Chiang CM, Bradner JE, Shilatifard A, Roy AL. Correction: Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells. Plos One. 10: e0126328. PMID 25902070 DOI: 10.1371/journal.pone.0126328  0.76
2015 Luo Z, Gao X, Lin C, Smith ER, Marshall SA, Swanson SK, Florens L, Washburn MP, Shilatifard A. Zic2 is an enhancer-binding factor required for embryonic stem cell specification. Molecular Cell. 57: 685-94. PMID 25699711 DOI: 10.1016/j.molcel.2015.01.007  0.76
2015 Morgan MA, Shilatifard A. Chromatin signatures of cancer. Genes & Development. 29: 238-49. PMID 25644600 DOI: 10.1101/gad.255182.114  0.76
2015 Zhang P, Chaturvedi CP, Tremblay V, Cramet M, Brunzelle JS, Skiniotis G, Brand M, Shilatifard A, Couture JF. A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation. Genes & Development. 29: 123-8. PMID 25593305 DOI: 10.1101/gad.254870.114  0.76
2015 Liang K, Gao X, Gilmore JM, Florens L, Washburn MP, Smith E, Shilatifard A. Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing. Molecular and Cellular Biology. 35: 928-38. PMID 25561469 DOI: 10.1128/MCB.01426-14  0.4
2014 Tremblay V, Zhang P, Chaturvedi CP, Thornton J, Brunzelle JS, Skiniotis G, Shilatifard A, Brand M, Couture JF. Molecular basis for DPY-30 association to COMPASS-like and NURF complexes. Structure (London, England : 1993). 22: 1821-30. PMID 25456412 DOI: 10.1016/j.str.2014.10.002  0.76
2014 Gardini A, Baillat D, Cesaroni M, Hu D, Marinis JM, Wagner EJ, Lazar MA, Shilatifard A, Shiekhattar R. Integrator regulates transcriptional initiation and pause release following activation. Molecular Cell. 56: 128-39. PMID 25201415 DOI: 10.1016/j.molcel.2014.08.004  0.76
2014 Herz HM, Morgan M, Gao X, Jackson J, Rickels R, Swanson SK, Florens L, Washburn MP, Eissenberg JC, Shilatifard A. Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling. Science (New York, N.Y.). 345: 1065-70. PMID 25170156 DOI: 10.1126/science.1255104  0.76
2014 Cao K, Shilatifard A. Inhibit globally, act locally: CDK7 inhibitors in cancer therapy. Cancer Cell. 26: 158-9. PMID 25117707 DOI: 10.1016/j.ccr.2014.07.020  0.76
2014 Cheng J, Blum R, Bowman C, Hu D, Shilatifard A, Shen S, Dynlacht BD. A role for H3K4 monomethylation in gene repression and partitioning of chromatin readers. Molecular Cell. 53: 979-92. PMID 24656132 DOI: 10.1016/j.molcel.2014.02.032  0.76
2014 Fowler T, Ghatak P, Price DH, Conaway R, Conaway J, Chiang CM, Bradner JE, Shilatifard A, Roy AL. Regulation of MYC expression and differential JQ1 sensitivity in cancer cells. Plos One. 9: e87003. PMID 24466310 DOI: 10.1371/journal.pone.0087003  0.76
2014 Thornton JL, Westfield GH, Takahashi YH, Cook M, Gao X, Woodfin AR, Lee JS, Morgan MA, Jackson J, Smith ER, Couture JF, Skiniotis G, Shilatifard A. Context dependency of Set1/COMPASS-mediated histone H3 Lys4 trimethylation. Genes & Development. 28: 115-20. PMID 24402317 DOI: 10.1101/gad.232215.113  0.76
2013 Hu D, Gao X, Morgan MA, Herz HM, Smith ER, Shilatifard A. The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers. Molecular and Cellular Biology. 33: 4745-54. PMID 24081332 DOI: 10.1128/MCB.01181-13  0.76
2013 Hu D, Garruss AS, Gao X, Morgan MA, Cook M, Smith ER, Shilatifard A. The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells. Nature Structural & Molecular Biology. 20: 1093-7. PMID 23934151 DOI: 10.1038/nsmb.2653  0.76
2013 Hu D, Smith ER, Garruss AS, Mohaghegh N, Varberg JM, Lin C, Jackson J, Gao X, Saraf A, Florens L, Washburn MP, Eissenberg JC, Shilatifard A. The little elongation complex functions at initiation and elongation phases of snRNA gene transcription. Molecular Cell. 51: 493-505. PMID 23932780 DOI: 10.1016/j.molcel.2013.07.003  0.76
2013 Morgan MA, Shilatifard A. Medicine. (Poly)combing the pediatric cancer genome for answers. Science (New York, N.Y.). 340: 823-4. PMID 23687038 DOI: 10.1126/science.1239223  0.76
2013 Morgan MA, Shilatifard A. Drosophila SETs its sights on cancer: Trr/MLL3/4 COMPASS-like complexes in development and disease. Molecular and Cellular Biology. 33: 1698-701. PMID 23459940 DOI: 10.1128/MCB.00203-13  0.76
2013 Lin C, Garruss AS, Luo Z, Guo F, Shilatifard A. The RNA Pol II elongation factor Ell3 marks enhancers in ES cells and primes future gene activation. Cell. 152: 144-56. PMID 23273992 DOI: 10.1016/j.cell.2012.12.015  0.4
2012 Luo Z, Lin C, Shilatifard A. The super elongation complex (SEC) family in transcriptional control. Nature Reviews. Molecular Cell Biology. 13: 543-7. PMID 22895430 DOI: 10.1038/nrm3417  0.4
2012 Luo Z, Lin C, Guest E, Garrett AS, Mohaghegh N, Swanson S, Marshall S, Florens L, Washburn MP, Shilatifard A. The super elongation complex family of RNA polymerase II elongation factors: gene target specificity and transcriptional output. Molecular and Cellular Biology. 32: 2608-17. PMID 22547686 DOI: 10.1128/MCB.00182-12  0.4
2012 Herz HM, Mohan M, Garrett AS, Miller C, Casto D, Zhang Y, Seidel C, Haug JS, Florens L, Washburn MP, Yamaguchi M, Shiekhattar R, Shilatifard A. Polycomb repressive complex 2-dependent and -independent functions of Jarid2 in transcriptional regulation in Drosophila. Molecular and Cellular Biology. 32: 1683-93. PMID 22354997 DOI: 10.1128/MCB.06503-11  0.76
2011 Smith ER, Lin C, Garrett AS, Thornton J, Mohaghegh N, Hu D, Jackson J, Saraf A, Swanson SK, Seidel C, Florens L, Washburn MP, Eissenberg JC, Shilatifard A. The little elongation complex regulates small nuclear RNA transcription. Molecular Cell. 44: 954-65. PMID 22195968 DOI: 10.1016/j.molcel.2011.12.008  0.76
2011 Takahashi YH, Westfield GH, Oleskie AN, Trievel RC, Shilatifard A, Skiniotis G. Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human. Proceedings of the National Academy of Sciences of the United States of America. 108: 20526-31. PMID 22158900 DOI: 10.1073/pnas.1109360108  0.76
2011 Schulze JM, Hentrich T, Nakanishi S, Gupta A, Emberly E, Shilatifard A, Kobor MS. Splitting the task: Ubp8 and Ubp10 deubiquitinate different cellular pools of H2BK123. Genes & Development. 25: 2242-7. PMID 22056669 DOI: 10.1101/gad.177220.111  0.76
2011 Mohan M, Herz HM, Smith ER, Zhang Y, Jackson J, Washburn MP, Florens L, Eissenberg JC, Shilatifard A. The COMPASS family of H3K4 methylases in Drosophila. Molecular and Cellular Biology. 31: 4310-8. PMID 21875999 DOI: 10.1128/MCB.06092-11  0.76
2011 Lin C, Garrett AS, De Kumar B, Smith ER, Gogol M, Seidel C, Krumlauf R, Shilatifard A. Dynamic transcriptional events in embryonic stem cells mediated by the super elongation complex (SEC). Genes & Development. 25: 1486-98. PMID 21764852 DOI: 10.1101/gad.2059211  0.76
2011 Henikoff S, Shilatifard A. Histone modification: cause or cog? Trends in Genetics : Tig. 27: 389-96. PMID 21764166 DOI: 10.1016/j.tig.2011.06.006  0.76
2011 Takahashi H, Parmely TJ, Sato S, Tomomori-Sato C, Banks CA, Kong SE, Szutorisz H, Swanson SK, Martin-Brown S, Washburn MP, Florens L, Seidel CW, Lin C, Smith ER, Shilatifard A, et al. Human mediator subunit MED26 functions as a docking site for transcription elongation factors. Cell. 146: 92-104. PMID 21729782 DOI: 10.1016/j.cell.2011.06.005  0.76
2011 Takahashi YH, Schulze JM, Jackson J, Hentrich T, Seidel C, Jaspersen SL, Kobor MS, Shilatifard A. Dot1 and histone H3K79 methylation in natural telomeric and HM silencing. Molecular Cell. 42: 118-26. PMID 21474073 DOI: 10.1016/j.molcel.2011.03.006  0.76
2011 Smith E, Lin C, Shilatifard A. The super elongation complex (SEC) and MLL in development and disease. Genes & Development. 25: 661-72. PMID 21460034 DOI: 10.1101/gad.2015411  0.4
2011 Yu Y, Srinivasan M, Nakanishi S, Leatherwood J, Shilatifard A, Sternglanz R. A conserved patch near the C terminus of histone H4 is required for genome stability in budding yeast. Molecular and Cellular Biology. 31: 2311-25. PMID 21444721 DOI: 10.1128/MCB.01432-10  0.76
2010 Mohan M, Lin C, Guest E, Shilatifard A. Licensed to elongate: a molecular mechanism for MLL-based leukaemogenesis. Nature Reviews. Cancer. 10: 721-8. PMID 20844554 DOI: 10.1038/nrc2915  0.4
2010 Herz HM, Madden LD, Chen Z, Bolduc C, Buff E, Gupta R, Davuluri R, Shilatifard A, Hariharan IK, Bergmann A. The H3K27me3 demethylase dUTX is a suppressor of Notch- and Rb-dependent tumors in Drosophila. Molecular and Cellular Biology. 30: 2485-97. PMID 20212086 DOI: 10.1128/MCB.01633-09  0.76
2010 Mohan M, Herz HM, Takahashi YH, Lin C, Lai KC, Zhang Y, Washburn MP, Florens L, Shilatifard A. Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom). Genes & Development. 24: 574-89. PMID 20203130 DOI: 10.1101/gad.1898410  0.4
2010 Lin C, Smith ER, Takahashi H, Lai KC, Martin-Brown S, Florens L, Washburn MP, Conaway JW, Conaway RC, Shilatifard A. AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia. Molecular Cell. 37: 429-37. PMID 20159561 DOI: 10.1016/j.molcel.2010.01.026  0.76
2010 Eissenberg JC, Shilatifard A. Histone H3 lysine 4 (H3K4) methylation in development and differentiation. Developmental Biology. 339: 240-9. PMID 19703438 DOI: 10.1016/j.ydbio.2009.08.017  0.76
2009 Camahort R, Shivaraju M, Mattingly M, Li B, Nakanishi S, Zhu D, Shilatifard A, Workman JL, Gerton JL. Cse4 is part of an octameric nucleosome in budding yeast. Molecular Cell. 35: 794-805. PMID 19782029 DOI: 10.1016/j.molcel.2009.07.022  0.76
2009 Wang P, Lin C, Smith ER, Guo H, Sanderson BW, Wu M, Gogol M, Alexander T, Seidel C, Wiedemann LM, Ge K, Krumlauf R, Shilatifard A. Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II. Molecular and Cellular Biology. 29: 6074-85. PMID 19703992 DOI: 10.1128/MCB.00924-09  0.76
2009 Schulze JM, Jackson J, Nakanishi S, Gardner JM, Hentrich T, Haug J, Johnston M, Jaspersen SL, Kobor MS, Shilatifard A. Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation. Molecular Cell. 35: 626-41. PMID 19682934 DOI: 10.1016/j.molcel.2009.07.017  0.76
2009 Trievel RC, Shilatifard A. WDR5, a complexed protein. Nature Structural & Molecular Biology. 16: 678-80. PMID 19578375 DOI: 10.1038/nsmb0709-678  0.76
2009 Dang W, Steffen KK, Perry R, Dorsey JA, Johnson FB, Shilatifard A, Kaeberlein M, Kennedy BK, Berger SL. Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature. 459: 802-7. PMID 19516333 DOI: 10.1038/nature08085  0.76
2009 Kim J, Guermah M, McGinty RK, Lee JS, Tang Z, Milne TA, Shilatifard A, Muir TW, Roeder RG. RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell. 137: 459-71. PMID 19410543 DOI: 10.1016/j.cell.2009.02.027  0.76
2009 Takahashi YH, Lee JS, Swanson SK, Saraf A, Florens L, Washburn MP, Trievel RC, Shilatifard A. Regulation of H3K4 trimethylation via Cps40 (Spp1) of COMPASS is monoubiquitination independent: implication for a Phe/Tyr switch by the catalytic domain of Set1. Molecular and Cellular Biology. 29: 3478-86. PMID 19398585 DOI: 10.1128/MCB.00013-09  0.76
2009 Berger SL, Kouzarides T, Shiekhattar R, Shilatifard A. An operational definition of epigenetics. Genes & Development. 23: 781-3. PMID 19339683 DOI: 10.1101/gad.1787609  0.76
2009 Li B, Jackson J, Simon MD, Fleharty B, Gogol M, Seidel C, Workman JL, Shilatifard A. Histone H3 lysine 36 dimethylation (H3K36me2) is sufficient to recruit the Rpd3s histone deacetylase complex and to repress spurious transcription. The Journal of Biological Chemistry. 284: 7970-6. PMID 19155214 DOI: 10.1074/jbc.M808220200  0.76
2008 Wu M, Wang PF, Lee JS, Martin-Brown S, Florens L, Washburn M, Shilatifard A. Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS. Molecular and Cellular Biology. 28: 7337-44. PMID 18838538 DOI: 10.1128/MCB.00976-08  0.4
2008 Smith ER, Winter B, Eissenberg JC, Shilatifard A. Regulation of the transcriptional activity of poised RNA polymerase II by the elongation factor ELL. Proceedings of the National Academy of Sciences of the United States of America. 105: 8575-9. PMID 18562276 DOI: 10.1073/pnas.0804379105  0.76
2008 Wang P, Bowl MR, Bender S, Peng J, Farber L, Chen J, Ali A, Zhang Z, Alberts AS, Thakker RV, Shilatifard A, Williams BO, Teh BT. Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice. Molecular and Cellular Biology. 28: 2930-40. PMID 18212049 DOI: 10.1128/MCB.00654-07  0.76
2008 Smith ER, Lee MG, Winter B, Droz NM, Eissenberg JC, Shiekhattar R, Shilatifard A. Drosophila UTX is a histone H3 Lys27 demethylase that colocalizes with the elongating form of RNA polymerase II. Molecular and Cellular Biology. 28: 1041-6. PMID 18039863 DOI: 10.1128/MCB.01504-07  0.76
2007 Lee JS, Shukla A, Schneider J, Swanson SK, Washburn MP, Florens L, Bhaumik SR, Shilatifard A. Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS. Cell. 131: 1084-96. PMID 18083099 DOI: 10.1016/j.cell.2007.09.046  0.76
2007 Allis CD, Berger SL, Cote J, Dent S, Jenuwien T, Kouzarides T, Pillus L, Reinberg D, Shi Y, Shiekhattar R, Shilatifard A, Workman J, Zhang Y. New nomenclature for chromatin-modifying enzymes. Cell. 131: 633-6. PMID 18022353 DOI: 10.1016/j.cell.2007.10.039  0.76
2007 Bhaumik SR, Smith E, Shilatifard A. Covalent modifications of histones during development and disease pathogenesis. Nature Structural & Molecular Biology. 14: 1008-16. PMID 17984963 DOI: 10.1038/nsmb1337  0.76
2007 Ingvarsdottir K, Edwards C, Lee MG, Lee JS, Schultz DC, Shilatifard A, Shiekhattar R, Berger SL. Histone H3 K4 demethylation during activation and attenuation of GAL1 transcription in Saccharomyces cerevisiae. Molecular and Cellular Biology. 27: 7856-64. PMID 17875926 DOI: 10.1128/MCB.00801-07  0.76
2007 Eissenberg JC, Lee MG, Schneider J, Ilvarsonn A, Shiekhattar R, Shilatifard A. The trithorax-group gene in Drosophila little imaginal discs encodes a trimethylated histone H3 Lys4 demethylase. Nature Structural & Molecular Biology. 14: 344-6. PMID 17351630 DOI: 10.1038/nsmb1217  0.76
2007 Lee MG, Norman J, Shilatifard A, Shiekhattar R. Physical and functional association of a trimethyl H3K4 demethylase and Ring6a/MBLR, a polycomb-like protein. Cell. 128: 877-87. PMID 17320162 DOI: 10.1016/j.cell.2007.02.004  0.76
2007 Wood A, Shukla A, Schneider J, Lee JS, Stanton JD, Dzuiba T, Swanson SK, Florens L, Washburn MP, Wyrick J, Bhaumik SR, Shilatifard A. Ctk complex-mediated regulation of histone methylation by COMPASS. Molecular and Cellular Biology. 27: 709-20. PMID 17088385 DOI: 10.1128/MCB.01627-06  0.76
2007 Eissenberg JC, Shilatifard A, Dorokhov N, Michener DE. Cdk9 is an essential kinase in Drosophila that is required for heat shock gene expression, histone methylation and elongation factor recruitment. Molecular Genetics and Genomics : Mgg. 277: 101-14. PMID 17001490 DOI: 10.1007/s00438-006-0164-2  0.76
2006 Schneider J, Bajwa P, Johnson FC, Bhaumik SR, Shilatifard A. Rtt109 is required for proper H3K56 acetylation: a chromatin mark associated with the elongating RNA polymerase II. The Journal of Biological Chemistry. 281: 37270-4. PMID 17046836 DOI: 10.1074/jbc.C600265200  0.76
2006 Tenney K, Gerber M, Ilvarsonn A, Schneider J, Gause M, Dorsett D, Eissenberg JC, Shilatifard A. Drosophila Rtf1 functions in histone methylation, gene expression, and Notch signaling. Proceedings of the National Academy of Sciences of the United States of America. 103: 11970-4. PMID 16882721 DOI: 10.1073/pnas.0603620103  0.76
2006 Krogan NJ, Cagney G, Yu H, Zhong G, Guo X, Ignatchenko A, Li J, Pu S, Datta N, Tikuisis AP, Punna T, Peregrín-Alvarez JM, Shales M, Zhang X, Davey M, ... ... Shilatifard A, et al. Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 440: 637-43. PMID 16554755 DOI: 10.1038/nature04670  0.76
2006 Eissenberg JC, Shilatifard A. Leaving a mark: the many footprints of the elongating RNA polymerase II. Current Opinion in Genetics & Development. 16: 184-90. PMID 16503129 DOI: 10.1016/j.gde.2006.02.004  0.76
2005 Gerber MA, Shilatifard A, Eissenberg JC. Mutational analysis of an RNA polymerase II elongation factor in Drosophila melanogaster. Molecular and Cellular Biology. 25: 7803-11. PMID 16107725 DOI: 10.1128/MCB.25.17.7803-7811.2005  0.76
2005 Kong SE, Banks CA, Shilatifard A, Conaway JW, Conaway RC. ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL. Proceedings of the National Academy of Sciences of the United States of America. 102: 10094-8. PMID 16006523 DOI: 10.1073/pnas.0503017102  0.76
2005 Gerber M, Tenney K, Conaway JW, Conaway RC, Eissenberg JC, Shilatifard A. Regulation of heat shock gene expression by RNA polymerase II elongation factor, Elongin A. The Journal of Biological Chemistry. 280: 4017-20. PMID 15611125 DOI: 10.1074/jbc.C400487200  0.76
2004 Gerber M, Eissenberg JC, Kong S, Tenney K, Conaway JW, Conaway RC, Shilatifard A. In vivo requirement of the RNA polymerase II elongation factor elongin A for proper gene expression and development. Molecular and Cellular Biology. 24: 9911-9. PMID 15509793 DOI: 10.1128/MCB.24.22.9911-9919.2004  0.76
2003 Kong SE, Shilatifard A, Conaway RC, Conaway JW. Preparation and Assay of RNA Polymerase II Elongation Factors Elongin and ELL Methods in Enzymology. 371: 276-283. PMID 14712707 DOI: 10.1016/S0076-6879(03)71020-9  0.76
2003 Shilatifard A, Conaway RC, Conaway JW. The RNA polymerase II elongation complex. Annual Review of Biochemistry. 72: 693-715. PMID 12676794 DOI: 10.1146/annurev.biochem.72.121801.161551  1
2002 Eissenberg JC, Ma J, Gerber MA, Christensen A, Kennison JA, Shilatifard A. dELL is an essential RNA polymerase II elongation factor with a general role in development. Proceedings of the National Academy of Sciences of the United States of America. 99: 9894-9. PMID 12096188 DOI: 10.1073/pnas.152193699  0.76
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