Sanford I. Bernstein - Publications

Affiliations: 
University of California, San Diego and San Diego State University 
Area:
Cell Biology, Biochemistry, Molecular Biology

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Chandran S, Suggs JA, Wang BJ, Han A, Bhide S, Cryderman DE, Moore SA, Bernstein SI, Wallrath LL, Melkani GC. Suppression of myopathic lamin mutations by muscle-specific activation of AMPK and modulation of downstream signaling. Human Molecular Genetics. PMID 30239736 DOI: 10.1093/hmg/ddy332  0.48
2018 Kronert WA, Bell KM, Viswanathan MC, Melkani GC, Trujillo AS, Huang A, Melkani A, Cammarato A, Swank DM, Bernstein SI. Prolonged cross-bridge binding triggers muscle dysfunction in a fly model of myosin-based hypertrophic cardiomyopathy. Elife. 7. PMID 30102150 DOI: 10.7554/eLife.38064  0.48
2017 Melkani GC, Bhide S, Han A, Vyas J, Livelo C, Bodmer R, Bernstein SI. TRiC/CCT chaperonins are essential for maintaining myofibril organization, cardiac physiological rhythm, and life span. Febs Letters. PMID 28963798 DOI: 10.1002/1873-3468.12860  0.48
2017 Suggs JA, Melkani GC, Glasheen BM, Detor MM, Melkani A, Marsan NP, Swank DM, Bernstein SI. A Drosophila model of dominant inclusion body myopathy 3 shows diminished myosin kinetics that reduce muscle power and yield myofibrillar defects. Disease Models & Mechanisms. PMID 28258125 DOI: 10.1242/dmm.028050  0.48
2016 Achal M, Trujillo AS, Melkani GC, Farman GP, Ocorr K, Viswanathan MC, Kaushik G, Newhard CS, Glasheen BM, Melkani A, Suggs JA, Moore JR, Swank DM, Bodmer R, Cammarato A, ... Bernstein SI, et al. A restrictive cardiomyopathy mutation in an invariant proline at the myosin head/rod junction enhances head flexibility and function, yielding muscle defects in Drosophila. Journal of Molecular Biology. PMID 27107639 DOI: 10.1016/j.jmb.2016.04.021  0.48
2016 Bloemink MJ, Melkani GC, Bernstein SI, Geeves MA. The Relay/Converter Interface Influences Hydrolysis of ATP by Skeletal Muscle Myosin II. The Journal of Biological Chemistry. 291: 1763-73. PMID 26586917 DOI: 10.1074/jbc.M115.688002  0.48
2015 Kronert WA, Melkani GC, Melkani A, Bernstein SI. A Failure to Communicate: MYOSIN RESIDUES INVOLVED IN HYPERTROPHIC CARDIOMYOPATHY AFFECT INTER-DOMAIN INTERACTION. The Journal of Biological Chemistry. 290: 29270-80. PMID 26446785 DOI: 10.1074/jbc.M115.681874  0.48
2014 Trujillo AS, Ramos R, Bodmer R, Bernstein SI, Ocorr K, Melkani GC. Drosophila as a potential model to ameliorate mutant Huntington-mediated cardiac amyloidosis. Rare Diseases (Austin, Tex.). 2: e968003. PMID 26942103 DOI: 10.4161/2167549X.2014.968003  0.48
2014 Lee CF, Melkani GC, Bernstein SI. The UNC-45 myosin chaperone: from worms to flies to vertebrates. International Review of Cell and Molecular Biology. 313: 103-44. PMID 25376491 DOI: 10.1016/B978-0-12-800177-6.00004-9  0.48
2014 Kronert WA, Melkani GC, Melkani A, Bernstein SI. Mapping interactions between myosin relay and converter domains that power muscle function. The Journal of Biological Chemistry. 289: 12779-90. PMID 24627474 DOI: 10.1074/jbc.M114.550673  0.48
2013 Melkani GC, Trujillo AS, Ramos R, Bodmer R, Bernstein SI, Ocorr K. Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart. Plos Genetics. 9: e1004024. PMID 24367279 DOI: 10.1371/journal.pgen.1004024  0.48
2013 Xie HB, Cammarato A, Rajasekaran NS, Zhang H, Suggs JA, Lin HC, Bernstein SI, Benjamin IJ, Golic KG. The NADPH metabolic network regulates human αB-crystallin cardiomyopathy and reductive stress in Drosophila melanogaster. Plos Genetics. 9: e1003544. PMID 23818860 DOI: 10.1371/journal.pgen.1003544  0.48
2012 Wang Y, Melkani GC, Suggs JA, Melkani A, Kronert WA, Cammarato A, Bernstein SI. Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness Molecular Biology of the Cell. 23: 2057-2065. PMID 22496423 DOI: 10.1091/mbc.E12-02-0120  0.48
2012 Kronert WA, Melkani GC, Melkani A, Bernstein SI. Alternative relay and converter domains tune native muscle myosin isoform function in Drosophila. Journal of Molecular Biology. 416: 543-57. PMID 22226837 DOI: 10.1016/j.jmb.2011.12.044  0.48
2012 Kaushik G, Zambon AC, Fuhrmann A, Bernstein SI, Bodmer R, Engler AJ, Cammarato A. Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction. Journal of Cellular and Molecular Medicine. 16: 1656-62. PMID 22225769 DOI: 10.1111/j.1582-4934.2011.01517.x  0.48
2012 Caldwell JT, Melkani GC, Huxford T, Bernstein SI. Transgenic expression and purification of myosin isoforms using the Drosophila melanogaster indirect flight muscle system. Methods (San Diego, Calif.). 56: 25-32. PMID 22178692 DOI: 10.1016/j.ymeth.2011.12.002  0.48
2011 Cammarato A, Li XE, Reedy MC, Lee CF, Lehman W, Bernstein SI. Structural basis for myopathic defects engendered by alterations in the myosin rod. Journal of Molecular Biology. 414: 477-84. PMID 22037585 DOI: 10.1016/j.jmb.2011.10.019  0.48
2011 Ramanath S, Wang Q, Bernstein SI, Swank DM. Disrupting the myosin converter-relay interface impairs Drosophila indirect flight muscle performance. Biophysical Journal. 101: 1114-22. PMID 21889448 DOI: 10.1016/j.bpj.2011.07.045  0.48
2011 Melkani GC, Bodmer R, Ocorr K, Bernstein SI. The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model. Plos One. 6: e22579. PMID 21799905 DOI: 10.1371/journal.pone.0022579  0.48
2011 Bloemink MJ, Melkani GC, Dambacher CM, Bernstein SI, Geeves MA. Two Drosophila myosin transducer mutants with distinct cardiomyopathies have divergent ADP and actin affinities. The Journal of Biological Chemistry. 286: 28435-43. PMID 21680742 DOI: 10.1074/jbc.M111.258228  0.48
2011 Lee CF, Hauenstein AV, Fleming JK, Gasper WC, Engelke V, Sankaran B, Bernstein SI, Huxford T. X-ray crystal structure of the UCS domain-containing UNC-45 myosin chaperone from Drosophila melanogaster. Structure (London, England : 1993). 19: 397-408. PMID 21397190 DOI: 10.1016/j.str.2011.01.002  0.48
2011 Lee CF, Melkani GC, Yu Q, Suggs JA, Kronert WA, Suzuki Y, Hipolito L, Price MG, Epstein HF, Bernstein SI. Drosophila UNC-45 accumulates in embryonic blastoderm and in muscles, and is essential for muscle myosin stability. Journal of Cell Science. 124: 699-705. PMID 21285246 DOI: 10.1242/jcs.078964  0.48
2010 Melkani GC, Lee CF, Cammarato A, Bernstein SI. Drosophila UNC-45 prevents heat-induced aggregation of skeletal muscle myosin and facilitates refolding of citrate synthase. Biochemical and Biophysical Research Communications. 396: 317-22. PMID 20403336 DOI: 10.1016/j.bbrc.2010.04.090  0.48
2010 Kronert WA, Melkani GC, Melkani A, Bernstein SI. Mutating the converter-relay interface of Drosophila myosin perturbs ATPase activity, actin motility, myofibril stability and flight ability. Journal of Molecular Biology. 398: 625-32. PMID 20362584 DOI: 10.1016/j.jmb.2010.03.049  0.48
2009 Miller MS, Dambacher CM, Knowles AF, Braddock JM, Farman GP, Irving TC, Swank DM, Bernstein SI, Maughan DW. Alternative S2 hinge regions of the myosin rod affect myofibrillar structure and myosin kinetics. Biophysical Journal. 96: 4132-43. PMID 19450484 DOI: 10.1016/j.bpj.2009.02.034  0.48
2009 Bloemink MJ, Dambacher CM, Knowles AF, Melkani GC, Geeves MA, Bernstein SI. Alternative exon 9-encoded relay domains affect more than one communication pathway in the Drosophila myosin head. Journal of Molecular Biology. 389: 707-21. PMID 19393244 DOI: 10.1016/j.jmb.2009.04.036  0.48
2008 Yang C, Ramanath S, Kronert WA, Bernstein SI, Maughan DW, Swank DM. Alternative versions of the myosin relay domain differentially respond to load to influence Drosophila muscle kinetics. Biophysical Journal. 95: 5228-37. PMID 18805920 DOI: 10.1529/biophysj.108.136192  0.48
2008 Littlefield KP, Ward AB, Chappie JS, Reedy MK, Bernstein SI, Milligan RA, Reedy MC. Similarities and differences between frozen-hydrated, rigor acto-S1 complexes of insect flight and chicken skeletal muscles. Journal of Molecular Biology. 381: 519-28. PMID 18588896 DOI: 10.1016/j.jmb.2008.06.029  0.48
2008 Kronert WA, Dambacher CM, Knowles AF, Swank DM, Bernstein SI. Alternative relay domains of Drosophila melanogaster myosin differentially affect ATPase activity, in vitro motility, myofibril structure and muscle function. Journal of Molecular Biology. 379: 443-56. PMID 18462751 DOI: 10.1016/j.jmb.2008.04.010  0.48
2008 Cammarato A, Dambacher CM, Knowles AF, Kronert WA, Bodmer R, Ocorr K, Bernstein SI. Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles. Molecular Biology of the Cell. 19: 553-62. PMID 18045988 DOI: 10.1091/mbc.E07-09-0890  0.48
2007 Miller BM, Bloemink MJ, Nyitrai M, Bernstein SI, Geeves MA. A variable domain near the ATP-binding site in Drosophila muscle myosin is part of the communication pathway between the nucleotide and actin-binding sites. Journal of Molecular Biology. 368: 1051-66. PMID 17379245 DOI: 10.1016/j.jmb.2007.02.042  0.48
2007 Suggs JA, Cammarato A, Kronert WA, Nikkhoy M, Dambacher CM, Megighian A, Bernstein SI. Alternative S2 Hinge Regions of the Myosin Rod Differentially Affect Muscle Function, Myofibril Dimensions and Myosin Tail Length Journal of Molecular Biology. 367: 1312-1329. PMID 17316684 DOI: 10.1016/j.jmb.2007.01.045  0.48
2006 Hao Y, Miller MS, Swank DM, Liu H, Bernstein SI, Maughan DW, Pollack GH. Passive stiffness in Drosophila indirect flight muscle reduced by disrupting paramyosin phosphorylation, but not by embryonic myosin S2 hinge substitution. Biophysical Journal. 91: 4500-6. PMID 17012313 DOI: 10.1529/biophysj.106.088492  0.48
2006 Melkani GC, Cammarato A, Bernstein SI. alphaB-crystallin maintains skeletal muscle myosin enzymatic activity and prevents its aggregation under heat-shock stress. Journal of Molecular Biology. 358: 635-45. PMID 16546210 DOI: 10.1016/j.jmb.2006.02.043  0.48
2006 Swank DM, Braddock J, Brown W, Lesage H, Bernstein SI, Maughan DW. An alternative domain near the ATP binding pocket of Drosophila myosin affects muscle fiber kinetics. Biophysical Journal. 90: 2427-35. PMID 16399836 DOI: 10.1529/biophysj.105.075184  0.48
2005 Miller BM, Zhang S, Suggs JA, Swank DM, Littlefield KP, Knowles AF, Bernstein SI. An alternative domain near the nucleotide-binding site of Drosophila muscle myosin affects ATPase kinetics. Journal of Molecular Biology. 353: 14-25. PMID 16154586 DOI: 10.1016/j.jmb.2005.08.012  0.48
2005 Liu H, Miller MS, Swank DM, Kronert WA, Maughan DW, Bernstein SI. Paramyosin phosphorylation site disruption affects indirect flight muscle stiffness and power generation in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 102: 10522-7. PMID 16020538 DOI: 10.1073/pnas.0500945102  0.48
2004 Swank DM, Kronert WA, Bernstein SI, Maughan DW. Alternative N-terminal regions of Drosophila myosin heavy chain tune muscle kinetics for optimal power output. Biophysical Journal. 87: 1805-14. PMID 15345559 DOI: 10.1529/biophysj.103.032078  0.48
2003 Miller BM, Nyitrai M, Bernstein SI, Geeves MA. Kinetic analysis of Drosophila muscle myosin isoforms suggests a novel mode of mechanochemical coupling. The Journal of Biological Chemistry. 278: 50293-300. PMID 14506231 DOI: 10.1074/jbc.M308318200  0.48
2003 Swank DM, Knowles AF, Kronert WA, Suggs JA, Morrill GE, Nikkhoy M, Manipon GG, Bernstein SI. Variable N-terminal regions of muscle myosin heavy chain modulate ATPase rate and actin sliding velocity. The Journal of Biological Chemistry. 278: 17475-82. PMID 12606545 DOI: 10.1074/jbc.M212727200  0.48
2003 Littlefield KP, Swank DM, Sanchez BM, Knowles AF, Warshaw DM, Bernstein SI. The converter domain modulates kinetic properties of Drosophila myosin. American Journal of Physiology. Cell Physiology. 284: C1031-8. PMID 12477668 DOI: 10.1152/ajpcell.00474.2002  0.48
2002 Swank DM, Knowles AF, Suggs JA, Sarsoza F, Lee A, Maughan DW, Bernstein SI. The myosin converter domain modulates muscle performance. Nature Cell Biology. 4: 312-6. PMID 11901423 DOI: 10.1038/ncb776  0.48
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