Gregory A. Petsko - Publications

Affiliations: 
Neurology and Neuroscience Weill Cornell Medical College, New York, NY, United States 
Area:
Protein Crystallography
Website:
http://vivo.med.cornell.edu/display/cwid-gpetsko

293 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Tu Y, Kreinbring CA, Hill M, Liu C, Petsko GA, McCune CD, Berkowitz DB, Liu D, Ringe D. Crystal Structures of Cystathionine β-Synthase from Saccharomyces cerevisiae: One Enzymatic Step at a Time. Biochemistry. PMID 29630349 DOI: 10.1021/acs.biochem.8b00092  1
2017 Campbell BC, Petsko GA, Liu CF. Crystal Structure of Green Fluorescent Protein Clover and Design of Clover-Based Redox Sensors. Structure (London, England : 1993). PMID 29307487 DOI: 10.1016/j.str.2017.12.006  0.72
2017 Wu R, Sanishvili R, Belitsky BR, Juncosa JI, Le HV, Lehrer HJ, Farley M, Silverman RB, Petsko GA, Ringe D, Liu D. PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28348215 DOI: 10.1073/pnas.1703019114  1
2017 Naffin-Olivos JL, Daab A, White A, Goldfarb NE, Milne AC, Liu D, Baikovitz J, Dunn BM, Rengarajan J, Petsko GA, Ringe D. Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c). Biochemistry. PMID 28346784 DOI: 10.1021/acs.biochem.6b01066  1
2017 Zahniser MP, Prasad S, Kneen MM, Kreinbring CA, Petsko GA, Ringe D, McLeish MJ. Structure and mechanism of benzaldehyde dehydrogenase from Pseudomonas putida ATCC 12633, a member of the Class 3 aldehyde dehydrogenase superfamily. Protein Engineering, Design & Selection : Peds. 1-8. PMID 28338942 DOI: 10.1093/protein/gzx015  1
2017 Deshpande AR, Pochapsky TC, Petsko GA, Ringe D. Dual chemistry catalyzed by human acireductone dioxygenase. Protein Engineering, Design & Selection : Peds. PMID 28062648 DOI: 10.1093/protein/gzw078  1
2016 Liu CF, Brandt GS, Hoang QQ, Naumova N, Lazarevic V, Hwang ES, Dekker J, Glimcher LH, Ringe D, Petsko GA. Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites. Proceedings of the National Academy of Sciences of the United States of America. 113: E6572-E6581. PMID 27791029 DOI: 10.1073/pnas.1613914113  1
2016 Bassil F, Fernagut PO, Bezard E, Pruvost A, Leste-Lasserre T, Hoang QQ, Ringe D, Petsko GA, Meissner WG. Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy. Proceedings of the National Academy of Sciences of the United States of America. PMID 27482103 DOI: 10.1073/pnas.1609291113  1
2016 Wang W, Nguyen LT, Burlak C, Chegini F, Guo F, Chataway T, Ju S, Fisher OS, Miller DW, Datta D, Wu F, Wu CX, Landeru A, Wells JA, Cookson MR, ... ... Petsko GA, et al. Caspase-1 causes truncation and aggregation of the Parkinson's disease-associated protein α-synuclein. Proceedings of the National Academy of Sciences of the United States of America. PMID 27482083 DOI: 10.1073/pnas.1610099113  1
2016 Deshpande AR, Wagenpfeil K, Pochapsky TC, Petsko GA, Ringe D. Metal-dependent function of a mammalian acireductone dioxygenase. Biochemistry. PMID 26858196 DOI: 10.1021/acs.biochem.5b01319  0.48
2015 Kim CH, Han BS, Moon J, Kim DJ, Shin J, Rajan S, Nguyen QT, Sohn M, Kim WG, Han M, Jeong I, Kim KS, Lee EH, Tu Y, Naffin-Olivos JL, ... ... Petsko GA, et al. Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 26124091 DOI: 10.1073/pnas.1509742112  1
2015 Barmada SJ, Ju S, Arjun A, Batarse A, Archbold HC, Peisach D, Li X, Zhang Y, Tank EM, Qiu H, Huang EJ, Ringe D, Petsko GA, Finkbeiner S. Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1. Proceedings of the National Academy of Sciences of the United States of America. 112: 7821-6. PMID 26056265 DOI: 10.1073/pnas.1509744112  1
2015 Small SA, Petsko GA. Retromer in Alzheimer disease, Parkinson disease and other neurological disorders Nature Reviews Neuroscience. 16: 126-132. PMID 25669742 DOI: 10.1038/nrn3896  1
2015 Berman DE, Ringe D, Petsko GA, Small SA. The use of pharmacological retromer chaperones in Alzheimer's disease and other endosomal-related disorders. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 12-8. PMID 25472693 DOI: 10.1007/s13311-014-0321-y  1
2015 Jackson KL, Dayton RD, Orchard EA, Ju S, Ringe D, Petsko GA, Maquat LE, Klein RL. Preservation of forelimb function by UPF1 gene therapy in a rat model of TDP-43-induced motor paralysis. Gene Therapy. 22: 20-8. PMID 25354681 DOI: 10.1038/gt.2014.101  1
2015 Barmada SJ, Ju S, Arjun A, Batarse A, Archbold HC, Peisach D, Li X, Zhang Y, Tank EMH, Qiu H, Huang EJ, Ringe D, Petsko GA, Finkbeiner S. Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1 Proceedings of the National Academy of Sciences of the United States of America. 112: 7821-7826. DOI: 10.1073/pnas.1509744112  1
2014 Choi MS, Nakamura T, Cho SJ, Han X, Holland EA, Qu J, Petsko GA, Yates JR, Liddington RC, Lipton SA. Transnitrosylation from DJ-1 to PTEN attenuates neuronal cell death in parkinson's disease models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15123-31. PMID 25378175 DOI: 10.1523/JNEUROSCI.4751-13.2014  1
2014 Keedy DA, van den Bedem H, Sivak DA, Petsko GA, Ringe D, Wilson MA, Fraser JS. Crystal cryocooling distorts conformational heterogeneity in a model Michaelis complex of DHFR. Structure (London, England : 1993). 22: 899-910. PMID 24882744 DOI: 10.1016/j.str.2014.04.016  1
2014 Naffin-Olivos JL, Georgieva M, Goldfarb N, Madan-Lala R, Dong L, Bizzell E, Valinetz E, Brandt GS, Yu S, Shabashvili DE, Ringe D, Dunn BM, Petsko GA, Rengarajan J. Mycobacterium tuberculosis Hip1 modulates macrophage responses through proteolysis of GroEL2. Plos Pathogens. 10: e1004132. PMID 24830429 DOI: 10.1371/journal.ppat.1004132  1
2014 Mecozzi VJ, Berman DE, Simoes S, Vetanovetz C, Awal MR, Patel VM, Schneider RT, Petsko GA, Ringe D, Small SA. Pharmacological chaperones stabilize retromer to limit APP processing. Nature Chemical Biology. 10: 443-9. PMID 24747528 DOI: 10.1038/nchembio.1508  1
2014 Auclair JR, Salisbury JP, Johnson JL, Petsko GA, Ringe D, Bosco DA, Agar NY, Santagata S, Durham HD, Agar JN. Artifacts to avoid while taking advantage of top-down mass spectrometry based detection of protein S-thiolation. Proteomics. 14: 1152-7. PMID 24634066 DOI: 10.1002/pmic.201300450  1
2014 Kreinbring CA, Remillard SP, Hubbard P, Brodkin HR, Leeper FJ, Hawksley D, Lai EY, Fulton C, Petsko GA, Ringe D. Structure of a eukaryotic thiaminase I. Proceedings of the National Academy of Sciences of the United States of America. 111: 137-42. PMID 24351929 DOI: 10.1073/pnas.1315882110  1
2013 Petsko GA. Open questions: Zombie projects, translational research, and the real secret of the inside of the cell Bmc Biology. 11. PMID 24228755 DOI: 10.1186/1741-7007-11-97  1
2013 Edayathumangalam R, Wu R, Garcia R, Wang Y, Wang W, Kreinbring CA, Bach A, Liao J, Stone TA, Terwilliger TC, Hoang QQ, Belitsky BR, Petsko GA, Ringe D, Liu D. Crystal structure of Bacillus subtilis GabR, an autorepressor and transcriptional activator of gabT. Proceedings of the National Academy of Sciences of the United States of America. 110: 17820-5. PMID 24127574 DOI: 10.1073/pnas.1315887110  1
2013 Shim JH, Greenblatt MB, Zou W, Huang Z, Wein MN, Brady N, Hu D, Charron J, Brodkin HR, Petsko GA, Zaller D, Zhai B, Gygi S, Glimcher LH, Jones DC. Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts. The Journal of Clinical Investigation. 123: 4010-22. PMID 23945236 DOI: 10.1172/JCI69443  1
2013 Auclair JR, Johnson JL, Liu Q, Salisbury JP, Rotunno MS, Petsko GA, Ringe D, Brown RH, Bosco DA, Agar JN. Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage. Biochemistry. 52: 6137-44. PMID 23927036 DOI: 10.1021/bi4006122  1
2013 Auclair JR, Brodkin HR, D'Aquino JA, Petsko GA, Ringe D, Agar JN. Structural consequences of cysteinylation of Cu/Zn-superoxide dismutase Biochemistry. 52: 6145-6150. PMID 23919400 DOI: 10.1021/bi400613h  1
2013 Sigala PA, Fafarman AT, Schwans JP, Fried SD, Fenn TD, Caaveiro JM, Pybus B, Ringe D, Petsko GA, Boxer SG, Herschlag D. Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site. Proceedings of the National Academy of Sciences of the United States of America. 110: E2552-61. PMID 23798390 DOI: 10.1073/pnas.1302191110  1
2013 Liu CF, Liu D, Momb J, Thomas PW, Lajoie A, Petsko GA, Fast W, Ringe D. A phenylalanine clamp controls substrate specificity in the quorum-quenching metallo-γ-lactonase from Bacillus thuringiensis Biochemistry. 52: 1603-1610. PMID 23387521 DOI: 10.1021/bi400050j  1
2013 Steele JW, Ju S, Lachenmayer ML, Liken J, Stock A, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, ... ... Petsko GA, et al. Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain. Molecular Psychiatry. 18: 882-8. PMID 22869031 DOI: 10.1038/mp.2012.115  1
2013 Steele JW, Lachenmayer ML, Ju S, Stock A, Liken J, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, ... ... Petsko GA, et al. Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model. Molecular Psychiatry. 18: 889-97. PMID 22850627 DOI: 10.1038/mp.2012.106  1
2012 Petsko GA. Hypothesis-driven genomics pays off Genome Biology. 176. PMID 23113994 DOI: 10.1186/gb4057  1
2012 Ringe D, Petsko GA. Behind the movement Cell. 150: 1093-1095. PMID 22980970 DOI: 10.1016/j.cell.2012.08.031  1
2012 Bharadwaj PR, Verdile G, Barr RK, Gupta V, Steele JW, Lachenmayer ML, Yue Z, Ehrlich ME, Petsko G, Ju S, Ringe D, Sankovich SE, Caine JM, Macreadie IG, Gandy S, et al. Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast. Journal of Alzheimer's Disease : Jad. 32: 949-67. PMID 22903131 DOI: 10.3233/JAD-2012-120178  1
2012 Auclair JR, Somasundaran M, Green KM, Evans JE, Schiffer CA, Ringe D, Petsko GA, Agar JN. Mass spectrometry tools for analysis of intermolecular interactions. Methods in Molecular Biology (Clifton, N.J.). 896: 387-98. PMID 22821539 DOI: 10.1007/978-1-4614-3704-8_26  1
2012 Petsko GA. Out of Africa. Genome Biology. 13: 162. PMID 22748283 DOI: 10.1186/gb-2012-13-6-162  1
2012 Davies CW, Chaney J, Korbel G, Ringe D, Petsko GA, Ploegh H, Das C. The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK). Bioorganic & Medicinal Chemistry Letters. 22: 3900-4. PMID 22617491 DOI: 10.1016/j.bmcl.2012.04.124  1
2012 Petsko GA. Goodbye, Columbus Genome Biology. 155. PMID 22594909 DOI: 10.1186/gb4018  1
2012 Petsko GA. Mending walls Bmc Biology. 10. PMID 22577990 DOI: 10.1186/1741-7007-10-41  1
2012 Petsko GA. Economies of scale. Genome Biology. 13: 154. PMID 22546553 DOI: 10.1186/gb-2012-13-4-154  1
2012 Petsko GA. A case of the flu Genome Biology. 146. PMID 22364112 DOI: 10.1186/PREACCEPT-1204100637683493  1
2012 Petsko GA. The dog particle Genome Biology. 13. PMID 22289440 DOI: 10.1186/gb-2012-13-1-142  1
2012 Petsko GA. Out of Africa Genome Biology. 162. DOI: 10.1186/gb4028  1
2012 Petsko GA. Apocalypse now? Genome Biology. 151. DOI: 10.1186/gb4012  1
2012 Petsko GA. The coming epidemic of neurologic disorders: What science is-and should be-doing about it Daedalus. 141: 98-107. DOI: 10.1162/DAED_a_00165  1
2011 Petsko GA. The Columnist Manifesto Genome Biology. 12. PMID 22206791 DOI: 10.1186/gb-2011-12-12-136  1
2011 Petsko GA. Dominoes. Genome Biology. 12: 134. PMID 22129215 DOI: 10.1186/gb-2011-12-11-134  1
2011 Petsko GA. Bailing out Genome Biology. 12. PMID 22035635 DOI: 10.1186/gb-2011-12-10-131  1
2011 Wang W, Perovic I, Chittuluru J, Kaganovich A, Nguyen LT, Liao J, Auclair JR, Johnson D, Landeru A, Simorellis AK, Ju S, Cookson MR, Asturias FJ, Agar JN, Webb BN, ... ... Petsko GA, et al. A soluble α-synuclein construct forms a dynamic tetramer. Proceedings of the National Academy of Sciences of the United States of America. 108: 17797-802. PMID 22006323 DOI: 10.1073/pnas.1113260108  1
2011 Petsko GA. The one new journal we might actually need. Genome Biology. 12: 129. PMID 21958590 DOI: 10.1186/gb-2011-12-9-129  1
2011 Petsko GA. Herding cats. Science Translational Medicine. 3: 97cm24. PMID 21865535  1
2011 Bosco DA, LaVoie MJ, Petsko GA, Ringe D. Proteostasis and movement disorders: Parkinson's disease and amyotrophic lateral sclerosis. Cold Spring Harbor Perspectives in Biology. 3: a007500. PMID 21844169 DOI: 10.1101/cshperspect.a007500  1
2011 Lazar LM, Fisher SZ, Moulin AG, Kovalevsky A, Novak WR, Langan P, Petsko GA, Ringe D. Time-of-flight neutron diffraction study of bovine γ-chymotrypsin at the Protein Crystallography Station. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 587-90. PMID 21543868 DOI: 10.1107/S1744309111009341  1
2011 Ju S, Tardiff DF, Han H, Divya K, Zhong Q, Maquat LE, Bosco DA, Hayward LJ, Brown RH, Lindquist S, Ringe D, Petsko GA. A yeast model of FUS/TLS-dependent cytotoxicity. Plos Biology. 9: e1001052. PMID 21541368 DOI: 10.1371/journal.pbio.1001052  1
2011 Brodkin HR, Novak WRP, Milne AC, D'Aquino JA, Karabacak NM, Goldberg IG, Agar JN, Payne MS, Petsko GA, Ondrechen MJ, Ringe D. Evidence of the participation of remote residues in the catalytic activity of co-type nitrile hydratase from Pseudomonas putida Biochemistry. 50: 4923-4935. PMID 21473592 DOI: 10.1021/bi101761e  1
2011 Petsko GA. There is a sanity clause. Genome Biology. 12: 105. PMID 21392413 DOI: 10.1186/gb-2011-12-2-105  1
2011 Petsko GA. Nothing to do and all day to do it in Genome Biology. 12. DOI: 10.1186/gb-2011-12-8-126  1
2011 Petsko GA. Food of the dogs Genome Biology. 12. DOI: 10.1186/gb-2011-12-7-122  1
2011 Petsko GA. Risky business Genome Biology. 12. DOI: 10.1186/gb-2011-12-6-119  1
2011 Petsko GA. In praise of model organisms Genome Biology. 12. DOI: 10.1186/gb-2011-12-5-115  1
2011 Petsko GA. The blue marble Genome Biology. 12. DOI: 10.1186/gb-2011-12-4-112  1
2011 Petsko GA. The walking dead Genome Biology. 12. DOI: 10.1186/gb-2011-12-3-108  1
2011 Petsko GA. Preserving some sanity Genome Biology. 12. DOI: 10.1186/gb-2011-12-1-102  1
2011 Petsko GA. Policy: Herding CATS Science Translational Medicine. 3. DOI: 10.1126/scitranslmed.3002837  1
2011 Petsko GA, Yates JR. Analyzing molecular interactions Current Protocols in Bioinformatics. DOI: 10.1002/0471250953.bi0801s36  1
2010 Petsko GA. The long and the short of it Genome Biology. 11. PMID 21205280 DOI: 10.1186/gb-2010-11-12-145  1
2010 Petsko G. Save university arts from the bean counters Nature. 468: 1003. PMID 21179122 DOI: 10.1038/4681003a  1
2010 Petsko GA. Every dog has his day in court Genome Biology. 11. PMID 21122171 DOI: 10.1186/gb-2010-11-11-139  1
2010 Auclair JR, Boggio KJ, Petsko GA, Ringe D, Agar JN. Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis Proceedings of the National Academy of Sciences of the United States of America. 107: 21394-21399. PMID 21098299 DOI: 10.1073/pnas.1015463107  1
2010 Petsko GA. A Faustian bargain Genome Biology. 11. PMID 21062515 DOI: 10.1186/gb-2010-11-10-138  1
2010 Petsko GA. Shadows on the wall Genome Biology. 11. PMID 20863416 DOI: 10.1186/gb-2010-11-9-136  1
2010 Lewandowski NM, Ju S, Verbitsky M, Ross B, Geddie ML, Rockenstein E, Adame A, Muhammad A, Vonsattel JP, Ringe D, Cote L, Lindquist S, Masliah E, Petsko GA, Marder K, et al. Polyamine pathway contributes to the pathogenesis of Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. 107: 16970-5. PMID 20837543 DOI: 10.1073/pnas.1011751107  1
2010 Petsko GA. When the pie is too small. Genome Biology. 11: 127. PMID 20812422 DOI: 10.1186/gb-2010-11-7-127  1
2010 Petsko GA. The past is a foreign country Genome Biology. 11. PMID 20796324 DOI: 10.1186/gb-2010-11-8-131  1
2010 Petsko GA. Hand-made biology Genome Biology. 11. PMID 20591201 DOI: 10.1186/gb-2010-11-6-124  1
2010 Petsko GA. When failure should be the option Bmc Biology. 8. PMID 20529239 DOI: 10.1186/1741-7007-8-61  1
2010 Petsko GA. And they said it wouldn't last... Genome Biology. 11. PMID 20441616 DOI: 10.1186/gb-2010-11-5-121  1
2010 Petsko GA. The devil's in the details Genome Biology. 11. PMID 20441608 DOI: 10.1186/gb-2010-11-4-117  1
2010 Petsko GA. No stone unturned Genome Biology. 11. PMID 20353546 DOI: 10.1186/gb-2010-11-3-112  1
2010 Petsko GA. Lost in translation Genome Biology. 11. PMID 20210984 DOI: 10.1186/gb-2010-11-2-107  1
2010 Petsko GA. Rising in the East Genome Biology. 11. PMID 20156314 DOI: 10.1186/gb-2010-11-1-102  1
2010 Brandt GS, Kneen MM, Petsko GA, Ringe D, McLeish MJ. Active-site engineering of benzaldehyde lyase shows that a point mutation can confer both new reactivity and susceptibility to mechanism-based inhibition Journal of the American Chemical Society. 132: 438-439. PMID 20030408 DOI: 10.1021/ja907064w  1
2010 Petsko GA. When bigger is better Bmc Biology. 8. DOI: 10.1186/1741-7007-8-43  1
2010 Baxevanis AD, Davison DB, Page RDM, Petsko GA, Stein LD, Stormo GD, Yates J. Current Protocols in Bioinformatics: Preface Current Protocols in Bioinformatics. iii-vi. DOI: 10.1002/0471250953.biprefs01  1
2009 Petsko GA. Big science, little science Embo Reports. 10: 1282. PMID 19949404 DOI: 10.1038/embor.2009.240  1
2009 Petsko GA. The dog days of autumn. Genome Biology. 10: 112. PMID 19889199 DOI: 10.1186/gb-2009-10-10-112  1
2009 Ringe D, Petsko GA. What are pharmacological chaperones and why are they interesting? Journal of Biology. 8. PMID 19833004 DOI: 10.1186/jbiol186  1
2009 Petsko GA. An issue to remember. Genome Biology. 10: 111. PMID 19785720  1
2009 Petsko GA. Wimps? What wimps? Genome Biology. 10: 109. PMID 19664191  1
2009 Petsko GA. What my genome told me--and what it didn't. Genome Biology. 10: 108. PMID 19591645  1
2009 Petsko GA. Crystallographic cryoenzymology and the legacy of Tony Fink Current Protein and Peptide Science. 10: 416-423. PMID 19538155 DOI: 10.2174/138920309789351985  1
2009 Landon MR, Lieberman RL, Hoang QQ, Ju S, Caaveiro JM, Orwig SD, Kozakov D, Brenke R, Chuang GY, Beglov D, Vajda S, Petsko GA, Ringe D. Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase. Journal of Computer-Aided Molecular Design. 23: 491-500. PMID 19521672 DOI: 10.1007/s10822-009-9283-2  1
2009 Petsko GA. Render unto Darwin. Genome Biology. 10: 106. PMID 19519942  1
2009 Sigala PA, Caaveiro JM, Ringe D, Petsko GA, Herschlag D. Hydrogen bond coupling in the ketosteroid isomerase active site. Biochemistry. 48: 6932-9. PMID 19469568 DOI: 10.1021/bi900713j  1
2009 Petsko GA. Guilt by association. Genome Biology. 10: 104. PMID 19439034  1
2009 Lieberman RL, D'aquino JA, Ringe D, Petsko GA. Effects of pH and iminosugar pharmacological chaperones on lysosomal glycosidase structure and stability. Biochemistry. 48: 4816-27. PMID 19374450 DOI: 10.1021/bi9002265  1
2009 Petsko GA. Too big to succeed? Genome Biology. 10: 103. PMID 19344496  1
2009 Petsko GA. The greatest book you never read. Embo Reports. 10: 298. PMID 19337296 DOI: 10.1038/embor.2009.39  1
2009 Brandt GS, Kneen MM, Chakraborty S, Baykal AT, Nemeria N, Yep A, Ruby DI, Petsko GA, Kenyon GL, McLeish MJ, Jordan F, Ringe D. Snapshot of a reaction intermediate: analysis of benzoylformate decarboxylase in complex with a benzoylphosphonate inhibitor. Biochemistry. 48: 3247-57. PMID 19320438 DOI: 10.1021/bi801950k  1
2009 Novak WR, Moulin AG, Blakeley MP, Schlichting I, Petsko GA, Ringe D. A preliminary neutron diffraction study of gamma-chymotrypsin. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 317-20. PMID 19255494 DOI: 10.1107/S1744309109006630  1
2009 Petsko GA. Life is a Ponzi scheme. Genome Biology. 10: 101. PMID 19226430  1
2009 Chakraborty S, Nemeria NS, Balakrishnan A, Brandt GS, Kneen MM, Yep A, McLeish MJ, Kenyon GL, Petsko GA, Ringe D, Jordan F. Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase. Biochemistry. 48: 981-94. PMID 19140682 DOI: 10.1021/bi801810h  1
2009 Petsko GA. A harsh climate Genome Biology. 10. DOI: 10.1186/gb-2009-10-12-115  1
2009 Petsko GA. Advice and dissent Genome Biology. 10. DOI: 10.1186/gb-2009-10-11-113  1
2008 Petsko GA. A seat at the table. Genome Biology. 9: 113. PMID 19144208 DOI: 10.1186/gb-2008-9-12-113  1
2008 Petsko GA. The wisdom, and madness, of crowds. Genome Biology. 9: 112. PMID 19090959 DOI: 10.1186/gb-2008-9-11-112  1
2008 Petsko GA. Meta-morphosis. Genome Biology. 9: 111. PMID 18986505 DOI: 10.1186/gb-2008-9-10-111  1
2008 Petsko GA. When bubbles burst. Genome Biology. 9: 110. PMID 18831722 DOI: 10.1186/gb-2008-9-9-110  1
2008 Sigala PA, Kraut DA, Caaveiro JM, Pybus B, Ruben EA, Ringe D, Petsko GA, Herschlag D. Testing geometrical discrimination within an enzyme active site: constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole. Journal of the American Chemical Society. 130: 13696-708. PMID 18808119 DOI: 10.1021/ja803928m  1
2008 Petsko GA. Biodefense versus bioterrorism. Genome Biology. 9: 108. PMID 18771576 DOI: 10.1186/gb-2008-9-8-108  1
2008 Petsko GA. Having an impact (factor). Genome Biology. 9: 107. PMID 18671833 DOI: 10.1186/gb-2008-9-7-107  1
2008 Momb J, Wang C, Liu D, Thomas PW, Petsko GA, Guo H, Ringe D, Fast W. Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 2. Substrate modeling and active site mutations. Biochemistry. 47: 7715-25. PMID 18627130 DOI: 10.1021/bi8003704  1
2008 Liu D, Momb J, Thomas PW, Moulin A, Petsko GA, Fast W, Ringe D. Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures. Biochemistry. 47: 7706-14. PMID 18627129 DOI: 10.1021/bi800368y  1
2008 Petsko GA. It is alive. Genome Biology. 9: 106. PMID 18598376 DOI: 10.1186/gb-2008-9-6-106  1
2008 Ataie NJ, Hoang QQ, Zahniser MP, Tu Y, Milne A, Petsko GA, Ringe D. Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus. Biochemistry. 47: 7673-83. PMID 18576673 DOI: 10.1021/bi702188e  1
2008 Brandt GS, Nemeria N, Chakraborty S, McLeish MJ, Yep A, Kenyon GL, Petsko GA, Jordan F, Ringe D. Probing the active center of benzaldehyde lyase with substitutions and the pseudosubstrate analogue benzoylphosphonic acid methyl ester. Biochemistry. 47: 7734-43. PMID 18570438 DOI: 10.1021/bi8004413  1
2008 Ringe D, Petsko GA. Biochemistry. How enzymes work. Science (New York, N.Y.). 320: 1428-9. PMID 18556536 DOI: 10.1126/science.1159747  1
2008 Petsko GA. The new Manichaeans. Genome Biology. 9: 105. PMID 18522762 DOI: 10.1186/gb-2008-9-5-105  1
2008 Petsko GA. Not debatable. Genome Biology. 9: 104. PMID 18466637 DOI: 10.1186/gb-2008-9-4-104  1
2008 Petsko GA. The right to be wrong. Genome Biology. 9: 102. PMID 18328112 DOI: 10.1186/gb-2008-9-2-102  1
2008 Petsko GA. The story they missed. Genome Biology. 9: 101. PMID 18254934 DOI: 10.1186/gb-2008-9-1-101  1
2008 Petsko GA. Going to the dogs Genome Biology. 9. DOI: 10.1186/gb-2008-9-3-103  1
2008 Alber T, Gilbert WA, Ringe Ponzi DR, Petsko GA. The Role of Mobility in the Substrate Binding and Catalytic Machinery of Enzymes Ciba Foundation Symposium 93 - Mobility and Function in Proteins and Nucleic Acids. 4-24. DOI: 10.1002/9780470720752.ch2  0.72
2007 Petsko GA. Medicine man Genome Biology. 8. PMID 18177505 DOI: 10.1186/gb-2007-8-12-114  1
2007 Petsko GA. What if Watson had said "Apes evolved from man"? Genome Biology. 8. PMID 18086321 DOI: 10.1186/gb-2007-8-11-113  1
2007 Henzler-Wildman KA, Thai V, Lei M, Ott M, Wolf-Watz M, Fenn T, Pozharski E, Wilson MA, Petsko GA, Karplus M, Hübner CG, Kern D. Intrinsic motions along an enzymatic reaction trajectory. Nature. 450: 838-44. PMID 18026086 DOI: 10.1038/nature06410  1
2007 Petsko GA. They fought the law and the law won Genome Biology. 8. PMID 18001484 DOI: 10.1186/gb-2007-8-10-111  1
2007 Petsko GA. Strange days Genome Biology. 8. PMID 17915039 DOI: 10.1186/gb-2007-8-9-110  1
2007 Liu D, Thomas PW, Momb J, Hoang QQ, Petsko GA, Ringe D, Fast W. Structure and specificity of a quorum-quenching lactonase (AiiB) from Agrobacterium tumefaciens. Biochemistry. 46: 11789-99. PMID 17900178 DOI: 10.1021/bi7012849  1
2007 Petsko GA. My worries are no longer behind me Genome Biology. 8. PMID 17850676 DOI: 10.1186/gb-2007-8-8-109  1
2007 Liu D, Pozharski E, Lepore BW, Fu M, Silverman RB, Petsko GA, Ringe D. Inactivation of Escherichia coli L-aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid reveals "a tale of two mechanisms". Biochemistry. 46: 10517-27. PMID 17713924 DOI: 10.1021/bi700663n  1
2007 Petsko GA. An idea whose time has gone Genome Biology. 8. PMID 17608958 DOI: 10.1186/gb-2007-8-6-107  1
2007 Munih P, Moulin A, Stamper CC, Bennett B, Ringe D, Petsko GA, Holz RC. X-ray crystallographic characterization of the Co(II)-substituted Tris-bound form of the aminopeptidase from Aeromonas proteolytica. Journal of Inorganic Biochemistry. 101: 1099-107. PMID 17574677 DOI: 10.1016/j.jinorgbio.2007.03.010  1
2007 Petsko GA. It can't happen here - Can it? Genome Biology. 8. PMID 17472734 DOI: 10.1186/gb-2007-8-4-105  1
2007 Petsko GA. A day in the life of a genome biologist in the not-too-distant future Genome Biology. 8. PMID 17397521 DOI: 10.1186/gb-2007-8-3-104  1
2007 Petsko GA. And the second shall be first Genome Biology. 8. PMID 17328789 DOI: 10.1186/gb-2007-8-2-103  1
2007 Petsko GA. Jumping the shark Genome Biology. 8. PMID 17274836 DOI: 10.1186/gb-2007-8-1-101  1
2007 Lieberman RL, Wustman BA, Huertas P, Powe AC, Pine CW, Khanna R, Schlossmacher MG, Ringe D, Petsko GA. Structure of acid beta-glucosidase with pharmacological chaperone provides insight into Gaucher disease. Nature Chemical Biology. 3: 101-7. PMID 17187079 DOI: 10.1038/nchembio850  1
2007 Petsko GA. A truly titanic figure in science Genome Biology. 8. DOI: 10.1186/gb-2007-8-7-108  1
2007 Petsko GA. Inconvenient truths Genome Biology. 8. DOI: 10.1186/gb-2007-8-5-106  1
2006 Petsko GA. An introduction to modeling structure from sequence. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. Unit 5.1. PMID 18428765 DOI: 10.1002/0471250953.bi0501s15  1
2006 Petsko GA. A model worth considering? Genome Biology. 7. PMID 17201935 DOI: 10.1186/gb-2006-7-12-121  1
2006 Petsko GA. Do the math Genome Biology. 7. PMID 17147768 DOI: 10.1186/gb.2006-7-11-119  1
2006 Ding X, Rasmussen BF, Petsko GA, Ringe D. Direct crystallographic observation of an acyl-enzyme intermediate in the elastase-catalyzed hydrolysis of a peptidyl ester substrate: Exploiting the "glass transition" in protein dynamics. Bioorganic Chemistry. 34: 410-23. PMID 17083959 DOI: 10.1016/j.bioorg.2006.10.002  1
2006 Petsko GA. Transformation Genome Biology. 7. PMID 17081278 DOI: 10.1186/gb-2006-7-10-117  1
2006 Petsko GA. Senior moments Genome Biology. 7. PMID 16953901 DOI: 10.1186/gb-2006-7-8-113  1
2006 Petsko GA. Facts and figures Genome Biology. 7. PMID 16879737 DOI: 10.1186/gb-2006-7-7-111  1
2006 Petsko GA. The ninth wave Genome Biology. 7. PMID 16817947 DOI: 10.1186/gb-2006-7-6-109  1
2006 Petsko GA. Instructions for repair Genome Biology. 7. PMID 16808010 DOI: 10.1186/gb-2006-7-4-106  1
2006 Petsko GA. The next epidemic Genome Biology. 7. PMID 16737558 DOI: 10.1186/gb-2006-7-5-108  1
2006 Kraut DA, Sigala PA, Pybus B, Liu CW, Ringe D, Petsko GA, Herschlag D. Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion hole. Plos Biology. 4: e99. PMID 16602823 DOI: 10.1371/journal.pbio.0040099  1
2006 Desmarais W, Bienvenue DL, Bzymek KP, Petsko GA, Ringe D, Holz RC. The high-resolution structures of the neutral and the low pH crystals of aminopeptidase from Aeromonas proteolytica. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 11: 398-408. PMID 16596389 DOI: 10.1007/s00775-006-0093-x  1
2006 Petsko GA. The system is broken Genome Biology. 7. PMID 16584532 DOI: 10.1186/gb-2006-7-3-105  1
2006 Das C, Hoang QQ, Kreinbring CA, Luchansky SJ, Meray RK, Ray SS, Lansbury PT, Ringe D, Petsko GA. Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1. Proceedings of the National Academy of Sciences of the United States of America. 103: 4675-80. PMID 16537382 DOI: 10.1073/pnas.0510403103  1
2006 Petsko GA. Sweden has the right idea Genome Biology. 7. PMID 16522217 DOI: 10.1186/gb-2006-7-2-103  1
2006 Mattos C, Bellamacina CR, Peisach E, Pereira A, Vitkup D, Petsko GA, Ringe D. Multiple solvent crystal structures: probing binding sites, plasticity and hydration. Journal of Molecular Biology. 357: 1471-82. PMID 16488429 DOI: 10.1016/j.jmb.2006.01.039  1
2006 Petsko GA. Essay: The highs and lows of scientific conferences Nature Reviews Molecular Cell Biology. 7: 231-234. PMID 16421519 DOI: 10.1038/nrm1832  1
2006 Zhou W, Zhu M, Wilson MA, Petsko GA, Fink AL. The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein. Journal of Molecular Biology. 356: 1036-48. PMID 16403519 DOI: 10.1016/j.jmb.2005.12.030  1
2006 Petsko GA. Fly's time Genome Biology. 7. DOI: 10.1186/gb-2006-7-9-115  1
2006 Petsko GA. Let's get our priorities straight Genome Biology. 7. DOI: 10.1186/gb-2006-7-1-101  1
2006 Petsko GA. Foxes and hounds Genome Biology. 6. DOI: 10.1186/gb-2005-6-13-124  1
2005 Petsko GA. H5N1 Genome Biology. 6: 121. PMID 16277753  1
2005 Petsko GA. Half right Genome Biology. 6. PMID 16207361 DOI: 10.1186/gb-2005-6-10-120  1
2005 Wilson MA, Ringe D, Petsko GA. The atomic resolution crystal structure of the YajL (ThiJ) protein from Escherichia coli: a close prokaryotic homologue of the Parkinsonism-associated protein DJ-1. Journal of Molecular Biology. 353: 678-91. PMID 16181642 DOI: 10.1016/j.jmb.2005.08.033  1
2005 Petsko GA. Trinity Genome Biology. 6. PMID 16168089 DOI: 10.1186/gb-2005-6-9-118  1
2005 Bzymek KP, Moulin A, Swierczek SI, Ringe D, Petsko GA, Bennett B, Holz RC. Kinetic, spectroscopic, and X-ray crystallographic characterization of the functional E151H aminopeptidase from Aeromonas proteolytica. Biochemistry. 44: 12030-40. PMID 16142900 DOI: 10.1021/bi0505823  1
2005 Liu D, Lepore BW, Petsko GA, Thomas PW, Stone EM, Fast W, Ringe D. Three-dimensional structure of the quorum-quenching N-acyl homoserine lactone hydrolase from Bacillus thuringiensis. Proceedings of the National Academy of Sciences of the United States of America. 102: 11882-7. PMID 16087890 DOI: 10.1073/pnas.0505255102  1
2005 Petsko GA. The life aquatic Genome Biology. 6. PMID 16086855 DOI: 10.1186/gb-2005-6-8-116  1
2005 Petsko GA. Superman's eyes Biochimica Et Biophysica Acta - General Subjects. 1724: 225-226. PMID 16006042 DOI: 10.1016/j.bbagen.2005.06.001  1
2005 Petsko GA. Eighty years ago Genome Biology. 6: 114. PMID 15998453  1
2005 Petsko GA. How may you help me? Genome Biology. 6. PMID 15960808 DOI: 10.1186/gb-2005-6-6-111  1
2005 Petsko GA. A matter of life and death Genome Biology. 6. PMID 15892876 DOI: 10.1186/gb-2005-6-5-109  1
2005 Pozharski E, Moulin A, Hewagama A, Shanafelt AB, Petsko GA, Ringe D. Diversity in hapten recognition: structural study of an anti-cocaine antibody M82G2. Journal of Molecular Biology. 349: 570-82. PMID 15885702 DOI: 10.1016/j.jmb.2005.03.080  1
2005 Petsko GA. Who owns the data? Genome Biology. 6. PMID 15833127 DOI: 10.1186/gb-2005-6-4-107  1
2005 Beilina A, Van Der Brug M, Ahmad R, Kesavapany S, Miller DW, Petsko GA, Cookson MR. Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability. Proceedings of the National Academy of Sciences of the United States of America. 102: 5703-8. PMID 15824318 DOI: 10.1073/pnas.0500617102  1
2005 Petsko GA. Feet in mouth disease Genome Biology. 6. PMID 15774031 DOI: 10.1186/gb-2005-6-3-105  1
2005 Petsko GA. Tsunami Genome Biology. 6. PMID 15693951 DOI: 10.1186/gb-2005-6-2-104  1
2005 Petsko GA. Who steals my identity steals trash Genome Biology. 6. DOI: 10.1186/gb-2005-6-12-122  1
2005 Petsko GA. H5NI Genome Biology. 6. DOI: 10.1186/gb-2005-6-11-121  1
2005 Petsko GA. Identity crisis Genome Biology. 6. DOI: 10.1186/gb-2004-6-1-102  1
2004 Petsko GA. Color blind Genome Biology. 5. PMID 15575974 DOI: 10.1186/gb-2004-5-12-119  1
2004 Petsko GA. The emperor's new shibboleth Genome Biology. 5. PMID 15537433  1
2004 Petsko GA. Twilight of a hero Genome Biology. 5. PMID 15461804 DOI: 10.1186/gb-2004-5-10-116  1
2004 Petsko GA. Fame is a bubble, but not for some Genome Biology. 5. PMID 15345037 DOI: 10.1186/gb-2004-5-9-114  1
2004 Yang J, Wang Y, Woolridge EM, Arora V, Petsko GA, Kozarich JW, Ringe D. Crystal structure of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida, a fumarase class II type cycloisomerase: enzyme evolution in parallel pathways. Biochemistry. 43: 10424-34. PMID 15301541 DOI: 10.1021/bi036205c  1
2004 Petsko GA. A drop in the bucket Genome Biology. 5. PMID 15287964 DOI: 10.1186/gb-2004-5-8-112  1
2004 Stamper CC, Bienvenue DL, Bennett B, Ringe D, Petsko GA, Holz RC. Spectroscopic and X-ray crystallographic characterization of bestatin bound to the aminopeptidase from Aeromonas (Vibrio) proteolytica. Biochemistry. 43: 9620-8. PMID 15274616 DOI: 10.1021/bi049126p  1
2004 Gray JV, Petsko GA, Johnston GC, Ringe D, Singer RA, Werner-Washburne M. "Sleeping beauty": quiescence in Saccharomyces cerevisiae. Microbiology and Molecular Biology Reviews : Mmbr. 68: 187-206. PMID 15187181 DOI: 10.1128/MMBR.68.2.187-206.2004  1
2004 Petsko GA. Pharmacogenomics arrives Genome Biology. 5. PMID 15186481 DOI: 10.1186/gb-2004-5-6-108  1
2004 Canet-Avilés RM, Wilson MA, Miller DW, Ahmad R, McLendon C, Bandyopadhyay S, Baptista MJ, Ringe D, Petsko GA, Cookson MR. The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proceedings of the National Academy of Sciences of the United States of America. 101: 9103-8. PMID 15181200 DOI: 10.1073/pnas.0402959101  1
2004 Fenn TD, Ringe D, Petsko GA. Xylose isomerase in substrate and inhibitor michaelis states: atomic resolution studies of a metal-mediated hydride shift. Biochemistry. 43: 6464-74. PMID 15157080 DOI: 10.1021/bi049812o  1
2004 Petsko GA. The ascent of man? Genome Biology. 5. PMID 15128435 DOI: 10.1186/gb-2004-5-5-106  1
2004 Petsko GA. Doctor Dunsel Genome Biology. 5. PMID 15059246 DOI: 10.1186/gb-2004-5-4-104  1
2004 Vogan EM, Bellamacina C, He X, Liu HW, Ringe D, Petsko GA. Crystal structure at 1.8 A resolution of CDP-D-glucose 4,6-dehydratase from Yersinia pseudotuberculosis. Biochemistry. 43: 3057-67. PMID 15023057 DOI: 10.1021/bi035547f  1
2004 Petsko GA. Good chemistry Genome Biology. 5. PMID 15003108 DOI: 10.1186/gb-2004-5-3-103  1
2004 Holyoak T, Kettner CA, Petsko GA, Fuller RS, Ringe D. Structural basis for differences in substrate selectivity in Kex2 and furin protein convertases. Biochemistry. 43: 2412-21. PMID 14992578 DOI: 10.1021/bi035849h  1
2004 Wilson MA, St Amour CV, Collins JL, Ringe D, Petsko GA. The 1.8-A resolution crystal structure of YDR533Cp from Saccharomyces cerevisiae: a member of the DJ-1/ThiJ/PfpI superfamily. Proceedings of the National Academy of Sciences of the United States of America. 101: 1531-6. PMID 14745011 DOI: 10.1073/pnas.0308089100  1
2004 Petsko GA. Powerless to stop myself Genome Biology. 5. DOI: 10.1186/gb-2004-5-7-110  1
2003 Holyoak T, Fenn TD, Wilson MA, Moulin AG, Ringe D, Petsko GA. Malonate: a versatile cryoprotectant and stabilizing solution for salt-grown macromolecular crystals. Acta Crystallographica. Section D, Biological Crystallography. 59: 2356-8. PMID 14646118 DOI: 10.1107/S0907444903021784  1
2003 Ringe D, Petsko GA. The 'glass transition' in protein dynamics: what it is, why it occurs, and how to exploit it. Biophysical Chemistry. 105: 667-80. PMID 14499926 DOI: 10.1016/S0301-4622(03)00096-6  1
2003 Wilson MA, Collins JL, Hod Y, Ringe D, Petsko GA. The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 9256-61. PMID 12855764 DOI: 10.1073/pnas.1133288100  1
2003 Holyoak T, Wilson MA, Fenn TD, Kettner CA, Petsko GA, Fuller RS, Ringe D. 2.4 A resolution crystal structure of the prototypical hormone-processing protease Kex2 in complex with an Ala-Lys-Arg boronic acid inhibitor. Biochemistry. 42: 6709-18. PMID 12779325 DOI: 10.1021/bi034434t  1
2003 Beebe JA, Arabshahi A, Clifton JG, Ringe D, Petsko GA, Frey PA. Galactose mutarotase: pH dependence of enzymatic mutarotation. Biochemistry. 42: 4414-20. PMID 12693937 DOI: 10.1021/bi020639a  1
2002 Kenyon GL, DeMarini DM, Fuchs E, Galas DJ, Kirsch JF, Leyh TS, Moos WH, Petsko GA, Ringe D, Rubin GM, Sheahan LC. Defining the mandate of proteomics in the post-genomics era: workshop report. Molecular & Cellular Proteomics : McP. 1: 763-80. PMID 12438560  1
2002 Desmarais WT, Bienvenue DL, Bzymek KP, Holz RC, Petsko GA, Ringe D. The 1.20 A resolution crystal structure of the aminopeptidase from Aeromonas proteolytica complexed with tris: a tale of buffer inhibition. Structure (London, England : 1993). 10: 1063-72. PMID 12176384 DOI: 10.1016/S0969-2126(02)00810-9  1
2002 Bahnson BJ, Anderson VE, Petsko GA. Structural mechanism of enoyl-CoA hydratase: three atoms from a single water are added in either an E1cb stepwise or concerted fashion. Biochemistry. 41: 2621-9. PMID 11851409 DOI: 10.1021/bi015844p  1
2002 Vitkup D, Ringe D, Karplus M, Petsko GA. Why protein R-factors are so large: a self-consistent analysis. Proteins. 46: 345-54. PMID 11835510 DOI: 10.1002/prot.10035  1
2002 Vogan EM, Bellamacina CR, He X, Foxman BM, Ringe D, Liu HW, Petsko GA. Purification, crystallization and molecular symmetry of CDP-D-glucose 4,6-dehydratase from Yersinia pseudotuberculosis. Acta Crystallographica. Section D, Biological Crystallography. 58: 370-3. PMID 11807280 DOI: 10.1107/S0907444901021473  1
2001 Hadfield A, Shammas C, Kryger G, Ringe D, Petsko GA, Ouyang J, Viola RE. Active site analysis of the potential antimicrobial target aspartate semialdehyde dehydrogenase. Biochemistry. 40: 14475-83. PMID 11724560 DOI: 10.1021/bi015713o  1
2000 McMillan FM, Cahoon M, White A, Hedstrom L, Petsko GA, Ringe D. Crystal structure at 2.4 A resolution of Borrelia burgdorferi inosine 5'-monophosphate dehydrogenase: evidence of a substrate-induced hinged-lid motion by loop 6. Biochemistry. 39: 4533-42. PMID 10758003 DOI: 10.1021/bi992645l  1
2000 Jeffery CJ, Gloss LM, Petsko GA, Ringe D. The role of residues outside the active site: structural basis for function of C191 mutants of Escherichia coli aspartate aminotransferase. Protein Engineering. 13: 105-12. PMID 10708649  1
2000 Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG. The catalytic pathway of cytochrome p450cam at atomic resolution. Science (New York, N.Y.). 287: 1615-22. PMID 10698731 DOI: 10.1126/science.287.5458.1615  1
2000 Petsko GA, Ringe D. Observation of unstable species in enzyme-catalyzed transformations using protein crystallography. Current Opinion in Chemical Biology. 4: 89-94. PMID 10679381  1
2000 Jeffery CJ, Bahnson BJ, Chien W, Ringe D, Petsko GA. Crystal structure of rabbit phosphoglucose isomerase, a glycolytic enzyme that moonlights as neuroleukin, autocrine motility factor, and differentiation mediator. Biochemistry. 39: 955-64. PMID 10653639 DOI: 10.1021/bi991604m  1
2000 Vitkup D, Ringe D, Petsko GA, Karplus M. Solvent mobility and the protein 'glass' transition. Nature Structural Biology. 7: 34-8. PMID 10625424 DOI: 10.1038/71231  1
1999 De Paola CC, Bennett B, Holz RC, Ringe D, Petsko GA. 1-Butaneboronic acid binding to Aeromonas proteolytica aminopeptidase: a case of arrested development. Biochemistry. 38: 9048-53. PMID 10413478 DOI: 10.1021/bi9900572  1
1999 Hadfield A, Kryger G, Ouyang J, Petsko GA, Ringe D, Viola R. Structure of aspartate-beta-semialdehyde dehydrogenase from Escherichia coli, a key enzyme in the aspartate family of amino acid biosynthesis. Journal of Molecular Biology. 289: 991-1002. PMID 10369777 DOI: 10.1006/jmbi.1999.2828  1
1999 Ringe D, Petsko GA. Quantum enzymology. Tunnel vision. Nature. 399: 417-8. PMID 10365952 DOI: 10.1038/20819  1
1999 Zhang Z, Komives EA, Sugio S, Blacklow SC, Narayana N, Xuong NH, Stock AM, Petsko GA, Ringe D. The role of water in the catalytic efficiency of triosephosphate isomerase. Biochemistry. 38: 4389-97. PMID 10194358 DOI: 10.1021/bi9826759  1
1999 Morollo AA, Petsko GA, Ringe D. Structure of a Michaelis complex analogue: propionate binds in the substrate carboxylate site of alanine racemase. Biochemistry. 38: 3293-301. PMID 10079072 DOI: 10.1021/bi9822729  1
1998 Jeffery CJ, Barry T, Doonan S, Petsko GA, Ringe D. Crystallization and preliminary X-ray diffraction analysis of aspartate aminotransferase from Saccharomyces cerevisiae. Acta Crystallographica. Section D, Biological Crystallography. 54: 659-61. PMID 9761867  1
1998 Sugio S, Kashima A, Kishimoto K, Peisach D, Petsko GA, Ringe D, Yoshimura T, Esaki N. Crystal structures of L201A mutant of D-amino acid aminotransferase at 2.0 A resolution: implication of the structural role of Leu201 in transamination. Protein Engineering. 11: 613-9. PMID 9749913  1
1998 Hasson MS, Schlichting I, Moulai J, Taylor K, Barrett W, Kenyon GL, Babbitt PC, Gerlt JA, Petsko GA, Ringe D. Evolution of an enzyme active site: the structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase. Proceedings of the National Academy of Sciences of the United States of America. 95: 10396-401. PMID 9724714 DOI: 10.1073/pnas.95.18.10396  1
1998 Hasson MS, Muscate A, McLeish MJ, Polovnikova LS, Gerlt JA, Kenyon GL, Petsko GA, Ringe D. The crystal structure of benzoylformate decarboxylase at 1.6 A resolution: diversity of catalytic residues in thiamin diphosphate-dependent enzymes. Biochemistry. 37: 9918-30. PMID 9665697 DOI: 10.1021/bi973047e  1
1998 Jeffery CJ, Barry T, Doonan S, Petsko GA, Ringe D. Crystal structure of Saccharomyces cerevisiae cytosolic aspartate aminotransferase. Protein Science : a Publication of the Protein Society. 7: 1380-7. PMID 9655342 DOI: 10.1002/pro.5560070614  1
1998 Yamakura F, Rardin RL, Petsko GA, Ringe D, Hiraoka BY, Nakayama K, Fujimura T, Taka H, Murayama K. Inactivation and destruction of conserved Trp159 of Fe-superoxide dismutase from Porphyromonas gingivalis by hydrogen peroxide. European Journal of Biochemistry / Febs. 253: 49-56. PMID 9578460  1
1997 Hasson MS, Schlichting I, McGowen MM, Woolridge EM, Kozarich JW, Petsko GA, Ringe D. Characterization of two crystal forms of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida. Acta Crystallographica. Section D, Biological Crystallography. 53: 352-3. PMID 15299946 DOI: 10.1107/S0907444996015648  1
1997 Harrison DH, Bohren KM, Petsko GA, Ringe D, Gabbay KH. The alrestatin double-decker: binding of two inhibitor molecules to human aldose reductase reveals a new specificity determinant. Biochemistry. 36: 16134-40. PMID 9405046 DOI: 10.1021/bi9717136  1
1997 Wallon G, Lovett ST, Magyar C, Svingor A, Szilagyi A, Zàvodszky P, Ringe D, Petsko GA. Sequence and homology model of 3-isopropylmalate dehydrogenase from the psychrotrophic bacterium Vibrio sp. I5 suggest reasons for thermal instability. Protein Engineering. 10: 665-72. PMID 9278279  1
1997 Brenner C, Garrison P, Gilmour J, Peisach D, Ringe D, Petsko GA, Lowenstein JM. Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins. Nature Structural Biology. 4: 231-8. PMID 9164465 DOI: 10.1038/nsb0397-231  1
1997 Vitkup D, Petsko GA, Karplus M. A comparison between molecular dynamics and X-ray results for dissociated CO in myoglobin. Nature Structural Biology. 4: 202-8. PMID 9164461  1
1997 Wallon G, Kryger G, Lovett ST, Oshima T, Ringe D, Petsko GA. Crystal structures of Escherichia coli and Salmonella typhimurium 3-isopropylmalate dehydrogenase and comparison with their thermophilic counterpart from Thermus thermophilus. Journal of Molecular Biology. 266: 1016-31. PMID 9086278 DOI: 10.1006/jmbi.1996.0797  1
1997 Shaw JP, Petsko GA, Ringe D. Determination of the structure of alanine racemase from Bacillus stearothermophilus at 1.9-A resolution. Biochemistry. 36: 1329-42. PMID 9063881 DOI: 10.1021/bi961856c  1
1995 Joseph-McCarthy D, Petsko GA, Karplus M. Use of a minimum perturbation approach to predict TIM mutant structures. Protein Engineering. 8: 1103-15. PMID 8819976  1
1995 Allen KN, Lavie A, Petsko GA, Ringe D. Design, synthesis, and characterization of a potent xylose isomerase inhibitor, D-threonohydroxamic acid, and high-resolution X-ray crystallographic structure of the enzyme-inhibitor complex Biochemistry. 34: 3742-3749. PMID 7893671 DOI: 10.1021/bi00011a032  1
1995 Mattos C, Giammona DA, Petsko GA, Ringe D. Structural analysis of the active site of porcine pancreatic elastase based on the X-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors Biochemistry. 34: 3193-3203. PMID 7880814  1
1995 Hasson MS, Muscate A, Henehan GT, Guidinger PF, Petsko GA, Ringe D, Kenyon GL. Purification and crystallization of benzoylformate decarboxylase. Protein Science : a Publication of the Protein Society. 4: 955-9. PMID 7663351 DOI: 10.1002/pro.5560040515  1
1995 Sugio S, Petsko GA, Manning JM, Soda K, Ringe D. Crystal structure of a D-amino acid aminotransferase: How the protein controls stereoselectivity Biochemistry. 34: 9661-9669. PMID 7626635  1
1995 Peisach E, Casebier D, Gallion SL, Furth P, Petsko GA, Hogan JC, Ringe D. Interaction of a peptidomimetic aminimide inhibitor with elastase. Science (New York, N.Y.). 269: 66-9. PMID 7604279  1
1995 Kryger G, Wallon G, Lovett ST, Ringe D, Petsko GA. Revision of the amino-acid sequence of 3-isopropylmalate dehydrogenase from Salmonella typhimurium by means of X-ray crystallography. Gene. 164: 85-7. PMID 7590327 DOI: 10.1016/0378-1119(95)00494-Q  1
1995 Schiering N, Tao X, Zeng H, Murphy JR, Petsko GA, Ringe D. Structures of the apo- and the metal ion-activated forms of the diphtheria tox repressor from Corynebacterium diphtheriae. Proceedings of the National Academy of Sciences of the United States of America. 92: 9843-50. PMID 7568230  1
1994 Allen KN, Lavie A, Farber GK, Glasfeld A, Petsko GA, Ringe D. Isotopic exchange plus substrate and inhibition kinetics of D-xylose isomerase do not support a proton-transfer mechanism Biochemistry. 33: 1481-1487. PMID 8312268  1
1994 Mattos C, Petsko GA, Karplus M. Analysis of two-residue turns in proteins Journal of Molecular Biology. 238: 733-747. PMID 8182746 DOI: 10.1006/jmbi.1994.1332  1
1994 Lavie A, Allen KN, Petsko GA, Ringe D. X-ray crystallographic structures of D-xylose isomerase-substrate complexes position the substrate and provide evidence for metal movement during catalysis Biochemistry. 33: 5469-5480. PMID 8180169  1
1994 Zhang Z, Sugio S, Komives EA, Liu KD, Knowles JR, Petsko GA, Ringe D. Crystal structure of recombinant chicken triosephosphate isomerase-phosphoglycolohydroxamate complex at 1.8-A resolution. Biochemistry. 33: 2830-7. PMID 8130195  1
1994 Ding X, Rasmussen BF, Petsko GA, Ringe D. Direct structural observation of an acyl-enzyme intermediate in the hydrolysis of an ester substrate by elastase. Biochemistry. 33: 9285-93. PMID 8049229  1
1994 Schiering N, Tao X, Murphy JR, Petsko GA, Ringe D. Crystallization and preliminary X-ray studies of the diphtheria Tox repressor from Corynebacterium diphtheriae. Journal of Molecular Biology. 244: 654-6. PMID 7990147 DOI: 10.1006/jmbi.1994.1760  1
1994 Allen KN, Lavie A, Glasfeld A, Tanada TN, Gerrity DP, Carlson SC, Farber GK, Petsko GA, Ringe D. Role of the divalent metal ion in sugar binding, ring opening, and isomerization by D-xylose isomerase: Replacement of a catalytic metal by an amino acid Biochemistry. 33: 1488-1494. PMID 7906142  1
1994 Mattos C, Rasmussen B, Ding X, Petsko GA, Ringe D. Analogous inhibitors of elastase do not always bind analogously Nature Structural Biology. 1: 55-58. PMID 7656008 DOI: 10.1038/nsb0194-55  1
1993 Petsko GA, Kenyon GL, Gerlt JA, Ringe D, Kozarich JW. On the origin of enzymatic species. Trends in Biochemical Sciences. 18: 372-6. PMID 8256284 DOI: 10.1016/0968-0004(93)90091-Z  1
1993 Jeffrey PD, Strong RK, Sieker LC, Chang CY, Campbell RL, Petsko GA, Haber E, Margolies MN, Sheriff S. 26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity. Proceedings of the National Academy of Sciences of the United States of America. 90: 10310-4. PMID 8234291 DOI: 10.1073/pnas.90.21.10310  1
1992 Howell PL, Warren C, Amatayakul-Chantler S, Petsko GA, Hajdu J. Activity of crystalline turkey egg white lysozyme. Proteins. 12: 91-9. PMID 1553384 DOI: 10.1002/prot.340120111  0.44
1992 Howell PL, Almo SC, Parsons MR, Hajdu J, Petsko GA. Structure determination of turkey egg-white lysozyme using Laue diffraction data. Acta Crystallographica. Section B, Structural Science. 48: 200-7. PMID 1515108 DOI: 10.1107/S0108768191012466  1
1991 Stoddard BL, Koenigs P, Porter N, Petratos K, Petsko GA, Ringe D. Observation of the light-triggered binding of pyrone to chymotrypsin by Laue x-ray crystallography Proceedings of the National Academy of Sciences of the United States of America. 88: 5503-5507. PMID 2062832  1
1991 Bash PA, Field MJ, Davenport RC, Petsko GA, Ringe D, Karplus M. Computer simulation and analysis of the reaction pathway of triosephosphate isomerase. Biochemistry. 30: 5826-32. PMID 2043624  1
1991 Davenport RC, Bash PA, Seaton BA, Karplus M, Petsko GA, Ringe D. Structure of the triosephosphate isomerase-phosphoglycolohydroxamate complex: an analogue of the intermediate on the reaction pathway. Biochemistry. 30: 5821-6. PMID 2043623  1
1991 Komives EA, Chang LC, Lolis E, Tilton RF, Petsko GA, Knowles JR. Electrophilic catalysis in triosephosphate isomerase: the role of histidine-95. Biochemistry. 30: 3011-9. PMID 2007138  1
1991 Danishefsky AT, Onnufer JJ, Petsko GA, Ringe D. Activity and structure of the active-site mutants R386Y and R386F of Escherichia coli aspartate aminotransferase. Biochemistry. 30: 1980-5. PMID 1993208  1
1991 Neidhart DJ, Howell PL, Petsko GA, Powers VM, Li RS, Kenyon GL, Gerlt JA. Mechanism of the reaction catalyzed by mandelate racemase. 2. Crystal structure of mandelate racemase at 2.5-A resolution: identification of the active site and possible catalytic residues. Biochemistry. 30: 9264-73. PMID 1892834  1
1990 Joseph D, Petsko GA, Karplus M. Anatomy of a conformational change: hinged "lid" motion of the triosephosphate isomerase loop. Science (New York, N.Y.). 249: 1425-8. PMID 2402636  1
1990 Stoddard BL, Bruhnke J, Porter N, Ringe D, Petsko GA. Structure and activity of two photoreversible cinnamates bound to chymotrypsin Biochemistry. 29: 4871-4879. PMID 2364065 DOI: 10.1021/bi00472a017  1
1990 Stoddard BL, Lynne Howell P, Ringe D, Petsko GA. The 2.1-Å resolution structure of iron superoxide dismutase from Pseudomonas ovalis Biochemistry®. 29: 8885-8893. PMID 2271564  1
1990 Stoddard BL, Bruhnke J, Koenigs P, Porter N, Ringe D, Petsko GA. Photolysis and deacylation of inhibited chymotrypsin Biochemistry. 29: 8042-8051. PMID 2261462  1
1990 Neidhart DJ, Kenyon GL, Gerlt JA, Petsko GA. Mandelate racemase and muconate lactonizing enzyme are mechanistically distinct and structurally homologous. Nature. 347: 692-4. PMID 2215699 DOI: 10.1038/347692a0  1
1990 Karplus M, Petsko GA. Molecular dynamics simulations in biology. Nature. 347: 631-9. PMID 2215695 DOI: 10.1038/347631a0  1
1990 Lolis E. Crystallographic analysis of the complex between triosephosphate isomerase and 2-phosphoglycolate at 2.5-Å resolution: Implications for catalysis Biochemistry®. 29: 6619-6625. PMID 2204418  0.88
1990 Lolis E. Structure of yeast triosephosphate isomerase at 1.9-Å resolution Biochemistry®. 29: 6609-6618. PMID 2204417  1
1990 Lolis E, Petsko GA. Transition-state analogues in protein crystallography: probes of the structural source of enzyme catalysis. Annual Review of Biochemistry. 59: 597-630. PMID 2197984 DOI: 10.1146/annurev.bi.59.070190.003121  1
1990 Neidhart DC, Howell PL, Petsko GA, Gerlt JA, Kozarich JW, Powers VM, Kenyon GL. Restructuring catalysis in the mandelate pathway. Biochemical Society Symposium. 57: 135-41. PMID 2099737  1
1990 Stoddard BL, Ringe D, Petsko GA. The structure of iron superoxide dismutase from Pseudomonas ovalis complexed with the inhibitor azide Protein Engineering, Design and Selection. 4: 113-119. PMID 2075185 DOI: 10.1093/protein/4.2.113  1
1989 Farber GK, Glasfeld A, Tiraby G, Ringe D, Petsko GA. Crystallographic studies of the mechanism of xylose isomerase Biochemistry. 28: 7289-7297. PMID 2510821  1
1988 Farber GK, Machin P, Almo SC, Petsko GA, Hajdu J. X-ray Laue diffraction from crystals of xylose isomerase Proceedings of the National Academy of Sciences of the United States of America. 85: 112-115. PMID 3422408  1
1988 Tilton RF, Petsko GA. A structure of sperm whale myoglobin at a nitrogen gas pressure of 145 atmospheres Biochemistry. 27: 6574-6582. PMID 3219355  1
1988 Glasfeld A, Farber GK, Ringe D, Marcel T, Drocourt D, Tiraby G, Petsko GA. Characterization of crystals of xylose isomerase from Streptomyces violaceoniger Journal of Biological Chemistry. 263: 14612-14613. PMID 3170558  1
1988 Neidhart DJ, Petsko GA. The refined crystal structure of subtilisin Carlsberg at 2.5 A resolution. Protein Engineering. 2: 271-6. PMID 3150541  0.32
1988 Neidhart DJ, Powers VM, Kenyon GL, Tsou AY, Ransom SC, Gerlt JA, Petsko GA. Preliminary x-ray data on crystals of mandelate racemase. The Journal of Biological Chemistry. 263: 9268-70. PMID 3132459  1
1988 Burley SK, Petsko GA. Weakly polar interactions in proteins. Advances in Protein Chemistry. 39: 125-89. PMID 3072867  0.92
1988 Nickbarg EB, Davenport RC, Petsko GA, Knowles JR. Triosephosphate isomerase: removal of a putatively electrophilic histidine residue results in a subtle change in catalytic mechanism. Biochemistry. 27: 5948-60. PMID 2847777  0.8
1987 Brünger AT, Campbell RL, Clore GM, Gronenborn AM, Karplus M, Petsko GA, Teeter MM. Solution of a protein crystal structure with a model obtained from NMR interproton distance restraints. Science (New York, N.Y.). 235: 1049-53. PMID 17782253 DOI: 10.1126/science.235.4792.1049  1
1987 Frauenfelder H, Hartmann H, Karplus M, Kuntz ID, Kuriyan J, Parak F, Petsko GA, Ringe D, Tilton RF, Connolly ML. Thermal expansion of a protein. Biochemistry. 26: 254-61. PMID 3828301  1
1987 Neidhart DJ, Distefano MD, Tanizawa K, Soda K, Walsh CT, Petsko GA. X-ray crystallographic studies of the alanine-specific racemase from Bacillus stearothermophilus. Overproduction, crystallization, and preliminary characterization. The Journal of Biological Chemistry. 262: 15323-6. PMID 3680197  1
1987 Stoddard B, Howell L, Asano S, Soda K, Tanizawa K, Ringe D, Petsko GA. Preliminary X-ray data for a D-amino acid amino-transferase from a novel thermophilic Bacillus. Journal of Molecular Biology. 196: 441-2. PMID 3656456  1
1987 Farber GK, Petsko GA, Ringe D. The 3.0 A crystal structure of xylose isomerase from Streptomyces olivochromogenes. Protein Engineering. 1: 459-66. PMID 3508293  1
1987 Kuriyan J, Karplus M, Petsko GA. Estimation of uncertainties in X-ray refinement results by use of perturbed structures. Proteins. 2: 1-12. PMID 3447165 DOI: 10.1002/prot.340020102  1
1987 Campbell RL, Petsko GA. Ribonuclease structure and catalysis: crystal structure of sulfate-free native ribonuclease A at 1.5-A resolution. Biochemistry. 26: 8579-84. PMID 3442678  1
1987 Alber TC, Davenport RC, Giammona DA, Lolis E, Petsko GA, Ringe D. Crystallography and site-directed mutagenesis of yeast triosephosphate isomerase: what can we learn about catalysis from a "simple" enzyme? Cold Spring Harbor Symposia On Quantitative Biology. 52: 603-13. PMID 3331346  1
1986 Kuriyan J, Wilz S, Karplus M, Petsko GA. X-ray structure and refinement of carbon-monoxy (Fe II)-myoglobin at 1.5 A resolution. Journal of Molecular Biology. 192: 133-54. PMID 3820301  1
1986 Kuriyan J, Petsko GA, Levy RM, Karplus M. Effect of anisotropy and anharmonicity on protein crystallographic refinement. An evaluation by molecular dynamics. Journal of Molecular Biology. 190: 227-54. PMID 3795269  1
1984 Seaton BA, Campbell RL, Petsko GA, Rose DR, Edelstein I, Marcus F. Preliminary X-ray crystallographic studies of pig kidney fructose-1,6-bisphosphatase. The Journal of Biological Chemistry. 259: 8915-6. PMID 6086617  1
1978 Petsko GA, Phillips DC, Williams RJ, Wilson IA. On the protein crystal chemistry of chloroplatinite ions: general principles and interactions with triose phosphate isomerase. Journal of Molecular Biology. 120: 345-59. PMID 650685 DOI: 10.1016/0022-2836(78)90423-0  1
1976 Banner DW, Bloomer Ac, Petsko GA, Phillips DC, Wilson IA. Atomic coordinates for triose phosphate isomerase from chicken muscle. Biochemical and Biophysical Research Communications. 72: 146-55. PMID 985462 DOI: 10.1016/0006-291X(76)90963-3  1
1975 Banner DW, Bloomer AC, Petsko GA, Phillips DC, Pogson CI, Wilson IA, Corran PH, Furth AJ, Milman JD, Offord RE, Priddle JD, Waley SG. Structure of chicken muscle triose phosphate isomerase determined crystallographically at 2.5 angstrom resolution using amino acid sequence data. Nature. 255: 609-14. PMID 1134550 DOI: 10.1038/255609a0  1
1972 Banner DW, Bloomer AC, Petsko GA, Phillips DC, Pogson CI. Crystallographic studies of chicken triose phosphate isomerase. Cold Spring Harbor Symposia On Quantitative Biology. 36: 151-5. PMID 4508133  1
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