Year |
Citation |
Score |
2023 |
Adler BA, Trinidad MI, Bellieny-Rabelo D, Zhang E, Karp HM, Skopintsev P, Thornton BW, Weissman RF, Yoon PH, Chen L, Hessler T, Eggers AR, Colognori D, Boger R, Doherty EE, ... ... Savage DF, et al. CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes. Nucleic Acids Research. PMID 37889041 DOI: 10.1093/nar/gkad890 |
0.448 |
|
2023 |
Armbruster EG, Lee J, Hutchings J, VanderWal AR, Enustun E, Adler BA, Aindow A, Deep A, Rodriguez ZK, Morgan CJ, Ghassemian M, Charles E, Cress BF, Savage DF, Doudna JA, et al. Sequential membrane- and protein-bound organelles compartmentalize genomes during phage infection. Biorxiv : the Preprint Server For Biology. PMID 37781618 DOI: 10.1101/2023.09.20.558163 |
0.464 |
|
2023 |
Stahl EC, Sabo JK, Kang MH, Allen R, Applegate E, Kim SE, Kwon Y, Seth A, Lemus N, Salinas-Rios V, Soczek KM, Trinidad M, Vo LT, Jeans C, Wozniak A, ... ... Savage DF, et al. Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 37403358 DOI: 10.1016/j.ymthe.2023.06.019 |
0.427 |
|
2022 |
Al-Shayeb B, Skopintsev P, Soczek KM, Stahl EC, Li Z, Groover E, Smock D, Eggers AR, Pausch P, Cress BF, Huang CJ, Staskawicz B, Savage DF, Jacobsen SE, Banfield JF, et al. Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors. Cell. 185: 4574-4586.e16. PMID 36423580 DOI: 10.1016/j.cell.2022.10.020 |
0.453 |
|
2022 |
Chandrasekaran SS, Agrawal S, Fanton A, Jangid AR, Charrez B, Escajeda AM, Son S, Mcintosh R, Tran H, Bhuiya A, de León Derby MD, Switz NA, Armstrong M, Harris AR, Prywes N, ... ... Savage DF, et al. Rapid detection of SARS-CoV-2 RNA in saliva via Cas13. Nature Biomedical Engineering. PMID 35953650 DOI: 10.1038/s41551-022-00917-y |
0.399 |
|
2022 |
Perier C, Nasinghe E, Charles I, Ssetaba LJ, Ahyong V, Bangs D, Beatty PR, Czudnochowski N, Diallo A, Dugan E, Fabius JM, Fong Baker H, Gardner J, Isaacs S, Joanah B, ... ... Savage DF, et al. Workshop-based learning and networking: a scalable model for research capacity strengthening in low- and middle-income countries. Global Health Action. 15: 2062175. PMID 35730550 DOI: 10.1080/16549716.2022.2062175 |
0.734 |
|
2021 |
LaFrance BJ, Cassidy-Amstutz C, Nichols RJ, Oltrogge LM, Nogales E, Savage DF. The encapsulin from Thermotoga maritima is a flavoprotein with a symmetry matched ferritin-like cargo protein. Scientific Reports. 11: 22810. PMID 34815415 DOI: 10.1038/s41598-021-01932-w |
0.411 |
|
2021 |
Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Díaz de León Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, ... ... Savage DF, et al. Publisher Correction: Accelerated RNA detection using tandem CRISPR nucleases. Nature Chemical Biology. PMID 34616098 DOI: 10.1038/s41589-021-00882-8 |
0.388 |
|
2021 |
Shams A, Higgins SA, Fellmann C, Laughlin TG, Oakes BL, Lew R, Kim S, Lukarska M, Arnold M, Staahl BT, Doudna JA, Savage DF. Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules. Nature Communications. 12: 5664. PMID 34580310 DOI: 10.1038/s41467-021-25992-8 |
0.585 |
|
2021 |
Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Díaz de León Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, ... ... Savage DF, et al. Accelerated RNA detection using tandem CRISPR nucleases. Nature Chemical Biology. PMID 34354262 DOI: 10.1038/s41589-021-00842-2 |
0.418 |
|
2021 |
Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, de León Derby MD, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, ... ... Savage DF, et al. Accelerated RNA detection using tandem CRISPR nucleases. Medrxiv : the Preprint Server For Health Sciences. PMID 33791736 DOI: 10.1101/2021.03.19.21253328 |
0.417 |
|
2020 |
Agrawal S, Fanton A, Chandrasekaran SS, Prywes N, Lukarska M, Biering SB, Smock DCJ, Mok A, Knott GJ, Van E, Dugan E, Kim S, Liu TY, Harris E, Stanley SA, ... ... Savage DF, et al. Rapid detection of SARS-CoV-2 with Cas13. Medrxiv : the Preprint Server For Health Sciences. PMID 33354689 DOI: 10.1101/2020.12.14.20247874 |
0.411 |
|
2020 |
Laughlin TG, Savage DF, Davies KM. Recent advances on the structure and function of NDH-1: The complex I of oxygenic photosynthesis. Biochimica Et Biophysica Acta. Bioenergetics. 1861: 148254. PMID 32645407 DOI: 10.1016/J.Bbabio.2020.148254 |
0.414 |
|
2020 |
Oltrogge LM, Chaijarasphong T, Chen AW, Bolin ER, Marqusee S, Savage DF. Multivalent interactions between CsoS2 and Rubisco mediate α-carboxysome formation. Nature Structural & Molecular Biology. 27: 281-287. PMID 32123388 DOI: 10.1038/S41594-020-0387-7 |
0.425 |
|
2019 |
Lee TH, Carpenter TS, D'haeseleer P, Savage DF, Yung MC. Encapsulin carrier proteins for enhanced expression of antimicrobial peptides. Biotechnology and Bioengineering. PMID 31709513 DOI: 10.1002/Bit.27222 |
0.437 |
|
2019 |
Desmarais JJ, Flamholz AI, Blikstad C, Dugan EJ, Laughlin TG, Oltrogge LM, Chen AW, Wetmore K, Diamond S, Wang JY, Savage DF. DABs are inorganic carbon pumps found throughout prokaryotic phyla. Nature Microbiology. PMID 31406332 DOI: 10.1038/S41564-019-0520-8 |
0.439 |
|
2019 |
Kundert K, Lucas JE, Watters KE, Fellmann C, Ng AH, Heineike BM, Fitzsimmons CM, Oakes BL, Qu J, Prasad N, Rosenberg OS, Savage DF, El-Samad H, Doudna JA, Kortemme T. Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs. Nature Communications. 10: 2127. PMID 31073154 DOI: 10.1038/S41467-019-09985-2 |
0.744 |
|
2019 |
Savage DF. Cas14: Big Advances from Small CRISPR Proteins. Biochemistry. PMID 30740978 DOI: 10.1021/Acs.Biochem.9B00035 |
0.46 |
|
2019 |
Oakes BL, Fellmann C, Rishi H, Taylor KL, Ren SM, Nadler DC, Yokoo R, Arkin AP, Doudna JA, Savage DF. CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification. Cell. 176: 254-267.e16. PMID 30633905 DOI: 10.1016/J.Cell.2018.11.052 |
0.773 |
|
2017 |
Higgins SA, Savage DF. Protein science by DNA sequencing: how advances in molecular biology are accelerating biochemistry. Biochemistry. PMID 28992412 DOI: 10.1021/Acs.Biochem.7B00886 |
0.4 |
|
2017 |
Higgins SA, Ounkap S, Savage DF. Rapid and Programmable Protein Mutagenesis Using Plasmid Recombineering. Acs Synthetic Biology. PMID 28707884 DOI: 10.1021/Acssynbio.7B00112 |
0.414 |
|
2017 |
Nichols RJ, Cassidy-Amstutz C, Chaijarasphong T, Savage DF. Encapsulins: molecular biology of the shell. Critical Reviews in Biochemistry and Molecular Biology. 1-12. PMID 28635326 DOI: 10.1080/10409238.2017.1337709 |
0.42 |
|
2016 |
Morgan SA, Nadler DC, Yokoo R, Savage DF. Biofuel metabolic engineering with biosensors. Current Opinion in Chemical Biology. 35: 150-158. PMID 27768949 DOI: 10.1016/J.Cbpa.2016.09.020 |
0.75 |
|
2016 |
Nadler DC, Morgan SA, Flamholz A, Kortright KE, Savage DF. Rapid construction of metabolite biosensors using domain-insertion profiling. Nature Communications. 7: 12266. PMID 27470466 DOI: 10.1038/Ncomms12266 |
0.781 |
|
2016 |
Cassidy-Amstutz C, Oltrogge LM, Going CC, Lee A, Teng PK, Quintanilla D, East-Seletsky A, Williams ER, Savage DF. Identification of a minimal peptide tag for in vivo and in vitro loading of encapsulin. Biochemistry. PMID 27224728 DOI: 10.1021/Acs.Biochem.6B00294 |
0.381 |
|
2016 |
Oakes BL, Nadler DC, Flamholz A, Fellmann C, Staahl BT, Doudna JA, Savage DF. Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch. Nature Biotechnology. 34: 646-51. PMID 27136077 DOI: 10.1038/Nbt.3528 |
0.775 |
|
2015 |
Chaijarasphong T, Nichols RJ, Kortright KE, Nixon CF, Teng PK, Oltrogge LM, Savage DF. Programmed ribosomal frameshifting mediates expression of the α-carboxysome. Journal of Molecular Biology. PMID 26608811 DOI: 10.1016/J.Jmb.2015.11.017 |
0.377 |
|
2014 |
Oakes BL, Nadler DC, Savage DF. Protein engineering of Cas9 for enhanced function Methods in Enzymology. 546: 491-511. PMID 25398355 DOI: 10.1016/B978-0-12-801185-0.00024-6 |
0.789 |
|
2014 |
Savage D. Sequestered: Molecular Physiology of Bacterial Microcompartments Biophysical Journal. 106: 445a. DOI: 10.1016/J.Bpj.2013.11.2517 |
0.365 |
|
2013 |
Chen AH, Robinson-Mosher A, Savage DF, Silver PA, Polka JK. The bacterial carbon-fixing organelle is formed by shell envelopment of preassembled cargo. Plos One. 8: e76127. PMID 24023971 DOI: 10.1371/Journal.Pone.0076127 |
0.516 |
|
2012 |
Chen AH, Afonso B, Silver PA, Savage DF. Spatial and temporal organization of chromosome duplication and segregation in the cyanobacterium Synechococcus elongatus PCC 7942. Plos One. 7: e47837. PMID 23112856 DOI: 10.1371/Journal.Pone.0047837 |
0.723 |
|
2012 |
Bonacci W, Teng PK, Afonso B, Niederholtmeyer H, Grob P, Silver PA, Savage DF. Modularity of a carbon-fixing protein organelle. Proceedings of the National Academy of Sciences of the United States of America. 109: 478-83. PMID 22184212 DOI: 10.1073/Pnas.1108557109 |
0.779 |
|
2010 |
Savage DF, O'Connell JD, Miercke LJ, Finer-Moore J, Stroud RM. Structural context shapes the aquaporin selectivity filter. Proceedings of the National Academy of Sciences of the United States of America. 107: 17164-9. PMID 20855585 DOI: 10.1073/Pnas.1009864107 |
0.511 |
|
2010 |
Niederholtmeyer H, Wolfstädter BT, Savage DF, Silver PA, Way JC. Engineering cyanobacteria to synthesize and export hydrophilic products. Applied and Environmental Microbiology. 76: 3462-6. PMID 20363793 DOI: 10.1128/Aem.00202-10 |
0.512 |
|
2010 |
Savage DF, Afonso B, Chen AH, Silver PA. Spatially ordered dynamics of the bacterial carbon fixation machinery. Science (New York, N.Y.). 327: 1258-61. PMID 20203050 DOI: 10.1126/Science.1186090 |
0.736 |
|
2009 |
Newby ZE, O'Connell JD, Gruswitz F, Hays FA, Harries WE, Harwood IM, Ho JD, Lee JK, Savage DF, Miercke LJ, Stroud RM. A general protocol for the crystallization of membrane proteins for X-ray structural investigation. Nature Protocols. 4: 619-37. PMID 19360018 DOI: 10.1038/Nprot.2009.27 |
0.679 |
|
2008 |
Savage DF, Way J, Silver PA. Defossiling fuel: how synthetic biology can transform biofuel production. Acs Chemical Biology. 3: 13-6. PMID 18205286 DOI: 10.1021/Cb700259J |
0.48 |
|
2008 |
Savage DF. Cell-free protein synthesis: Methods and protocols, edited by Alexander S. Spirin and James R. Swartz. Protein Science. 17: 962-963. DOI: 10.1110/Ps.083513908 |
0.407 |
|
2007 |
Savage DF, Anderson CL, Robles-Colmenares Y, Newby ZE, Stroud RM. Cell-free complements in vivo expression of the E. coli membrane proteome. Protein Science : a Publication of the Protein Society. 16: 966-76. PMID 17456747 DOI: 10.1110/Ps.062696307 |
0.77 |
|
2007 |
Savage DF, Stroud RM. Structural basis of aquaporin inhibition by mercury. Journal of Molecular Biology. 368: 607-17. PMID 17376483 DOI: 10.1016/J.Jmb.2007.02.070 |
0.509 |
|
2004 |
Egea PF, Shan SO, Napetschnig J, Savage DF, Walter P, Stroud RM. Substrate twinning activates the signal recognition particle and its receptor. Nature. 427: 215-21. PMID 14724630 DOI: 10.1038/Nature02250 |
0.741 |
|
2004 |
Lee JK, Khademi S, Harries W, Savage D, Miercke L, Stroud RM. Water and glycerol permeation through the glycerol channel GlpF and the aquaporin family. Journal of Synchrotron Radiation. 11: 86-8. PMID 14646142 DOI: 10.1107/S0909049503023872 |
0.758 |
|
2003 |
Savage DF, Egea PF, Robles-Colmenares Y, O'Connell JD, Stroud RM. Architecture and selectivity in aquaporins: 2.5 a X-ray structure of aquaporin Z. Plos Biology. 1: E72. PMID 14691544 DOI: 10.1371/Journal.Pbio.0000072 |
0.763 |
|
2003 |
Stroud RM, Savage D, Miercke LJ, Lee JK, Khademi S, Harries W. Selectivity and conductance among the glycerol and water conducting aquaporin family of channels. Febs Letters. 555: 79-84. PMID 14630323 DOI: 10.1016/S0014-5793(03)01195-5 |
0.737 |
|
2003 |
Keatinge-Clay AT, Shelat AA, Savage DF, Tsai SC, Miercke LJ, O'Connell JD, Khosla C, Stroud RM. Catalysis, specificity, and ACP docking site of Streptomyces coelicolor malonyl-CoA:ACP transacylase. Structure (London, England : 1993). 11: 147-54. PMID 12575934 DOI: 10.1016/S0969-2126(03)00004-2 |
0.698 |
|
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