Ali H. Ellebedy, Ph.D. - Publications

Affiliations: 
2011 Microbial Pathogenesis, Immunology, and Inflammation University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Immunology, Virology Biology

101 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Clark J, Hoxie I, Adelsberg DC, Sapse IA, Andreata-Santos R, Yong JS, Amanat F, Tcheou J, Raskin A, Singh G, González-Domínguez I, Edgar JE, Bournazos S, Sun W, Carreño JM, ... ... Ellebedy AH, et al. Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination. Biorxiv : the Preprint Server For Biology. PMID 38464151 DOI: 10.1101/2024.02.28.582613  0.437
2024 Boon J, Soudani N, Bricker T, Darling T, Seehra K, Patel N, Guebre-Xabier M, Smith G, Suthar M, Ellebedy A, Davis-Gardner M. Immunogenicity and efficacy of XBB.1.5 rS vaccine against EG.5.1 variant of SARS-CoV-2 in Syrian hamsters. Research Square. PMID 38405749 DOI: 10.21203/rs.3.rs-3873514/v1  0.566
2024 Zimmerman O, Altman Doss AM, Ying B, Liang CY, Mackin SR, Davis-Adams HG, Adams LJ, VanBlargan LA, Chen RE, Scheaffer SM, Desai P, Raju S, Mantia TL, O'Shaughnessy CC, Monroy JM, ... ... Ellebedy AH, et al. Immunoglobulin replacement products confer in vivo protection against SARS-CoV-2 XBB.1.5 Omicron variant despite poor neutralizing activity. Jci Insight. PMID 38175703 DOI: 10.1172/jci.insight.176359  0.407
2023 Wu NC, Ellebedy AH. Targeting neuraminidase: the next frontier for broadly protective influenza vaccines. Trends in Immunology. PMID 38103991 DOI: 10.1016/j.it.2023.11.001  0.628
2023 Lei R, Kim W, Lv H, Mou Z, Scherm MJ, Schmitz AJ, Turner JS, Tan TJC, Wang Y, Ouyang WO, Liang W, Rivera-Cardona J, Teo C, Graham CS, Brooke CB, ... ... Ellebedy AH, et al. Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase. Immunity. 56: 2621-2634.e6. PMID 37967533 DOI: 10.1016/j.immuni.2023.10.005  0.565
2023 Rijnink WF, Stadlbauer D, Puente-Massaguer E, Okba NMA, Kirkpatrick Roubidoux E, Strohmeier S, Mudd PA, Schmitz A, Ellebedy A, McMahon M, Krammer F. Characterization of non-neutralizing human monoclonal antibodies that target the M1 and NP of influenza A viruses. Journal of Virology. e0164622. PMID 37916834 DOI: 10.1128/jvi.01646-22  0.651
2023 Krammer F, Ellebedy AH. Variant-adapted COVID-19 booster vaccines. Science (New York, N.Y.). 382: 157-159. PMID 37824671 DOI: 10.1126/science.adh2712  0.474
2023 Mudd P, Borcherding N, Kim W, Quinn M, Han F, Zhou J, Sturtz A, Schmitz A, Lei T, Schattgen S, Klebert M, Suessen T, Middleton W, Goss C, Liu C, ... ... Ellebedy A, et al. Antigen-specific CD4 T cells exhibit distinct transcriptional phenotypes in the lymph node and blood following vaccination in humans. Research Square. PMID 37790414 DOI: 10.21203/rs.3.rs-3304466/v1  0.334
2023 Schattgen SA, Turner JS, Ghonim MA, Crawford JC, Schmitz AJ, Kim H, Zhou JQ, Awad W, Kim W, McIntire KM, Haile A, Klebert MK, Suessen T, Middleton WD, Teefey SA, ... ... Ellebedy AH, et al. Spatiotemporal development of the human T follicular helper cell response to Influenza vaccination. Biorxiv : the Preprint Server For Biology. PMID 37693531 DOI: 10.1101/2023.08.29.555186  0.526
2023 Hultgren S, Timm M, Tamadonfar K, Nye T, Pinkner J, Dodson K, Ellebedy A. Vaccination with Acinetobacter baumannii adhesin Abp2D provides protection against catheter-associated urinary tract infection. Research Square. PMID 37609304 DOI: 10.21203/rs.3.rs-3213777/v1  0.463
2023 Hansen L, McMahon M, Turner HL, Zhu X, Turner JS, Ozorowski G, Stadlbauer D, Vahokoski J, Schmitz AJ, Rizk AA, Alsoussi WB, Strohmeier S, Yu W, Choreño-Parra JA, Jiménez-Alvarez L, ... ... Ellebedy AH, et al. Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo. Immunity. PMID 37506693 DOI: 10.1016/j.immuni.2023.07.004  0.534
2023 Matz HC, McIntire KM, Ellebedy AH. 'Persistent germinal center responses: slow-growing trees bear the best fruits'. Current Opinion in Immunology. 83: 102332. PMID 37150126 DOI: 10.1016/j.coi.2023.102332  0.326
2023 Koutsakos M, Ellebedy AH. Immunological imprinting: Understanding COVID-19. Immunity. 56: 909-913. PMID 37105169 DOI: 10.1016/j.immuni.2023.04.012  0.452
2023 Cable J, Graham BS, Koup RA, Seder RA, Karikó K, Pardi N, Barouch DH, Sharma B, Rauch S, Nachbagauer R, Forsell MNE, Schotsaert M, Ellebedy AH, Loré K, Irvine DJ, et al. Progress in vaccine development for infectious diseases-a Keystone Symposia report. Annals of the New York Academy of Sciences. 1524: 65-86. PMID 37020354 DOI: 10.1111/nyas.14975  0.48
2023 Alsoussi WB, Malladi SK, Zhou JQ, Liu Z, Ying B, Kim W, Schmitz AJ, Lei T, Horvath SC, Sturtz AJ, McIntire KM, Evavold B, Han F, Scheaffer SM, Fox IF, ... ... Ellebedy AH, et al. SARS-CoV-2 Omicron boosting induces de novo B cell response in humans. Nature. PMID 37011668 DOI: 10.1038/s41586-023-06025-4  0.466
2023 Quinn M, Parra-Rodriguez L, Alsoussi WB, Ayres C, Klebert MK, Liu C, Suessen T, Scheaffer SM, Middleton WD, Teefey SA, Powderly WG, Diamond MS, Presti RM, Ellebedy AH, Turner JS, et al. Persons with HIV Develop Spike-Specific Lymph Node Germinal Center Responses following SARS-CoV-2 Vaccination. Journal of Immunology (Baltimore, Md. : 1950). PMID 36779802 DOI: 10.4049/jimmunol.2200920  0.47
2023 Cable J, Sun J, Cheon IS, Vaughan AE, Castro IA, Stein SR, López CB, Gostic KM, Openshaw PJM, Ellebedy AH, Wack A, Hutchinson E, Thomas MM, Langlois RA, Lingwood D, et al. Respiratory viruses: New frontiers-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 36722473 DOI: 10.1111/nyas.14958  0.366
2022 Lin FJ, Doss AMA, Davis-Adams HG, Adams LJ, Hanson CH, VanBlargan LA, Liang CY, Chen RE, Monroy JM, Wedner HJ, Kulczycki A, Mantia TL, O'Shaughnessy CC, Raju S, Zhao FR, ... ... Ellebedy AH, et al. SARS-CoV-2 booster vaccination rescues attenuated IgG1 memory B cell response in primary antibody deficiency patients. Frontiers in Immunology. 13: 1033770. PMID 36618402 DOI: 10.3389/fimmu.2022.1033770  0.525
2022 Palin AC, Alter G, Crotty S, Ellebedy AH, Lane MC, Lee FE, Locci M, Malaspina A, Mallia C, McElrath MJ, Pulendran B, Singh A, D'Souza MP. Author Correction: The persistence of memory: defining, engineering, and measuring vaccine durability. Nature Immunology. PMID 36572838 DOI: 10.1038/s41590-022-01414-9  0.32
2022 Stadlbauer D, McMahon M, Turner HL, Zhu X, Wan H, Carreño JM, O'Dell G, Strohmeier S, Khalil Z, Luksza M, van Bakel H, Simon V, Ellebedy AH, Wilson IA, Ward AB, et al. Antibodies targeting the neuraminidase active site inhibit influenza H3N2 viruses with an S245N glycosylation site. Nature Communications. 13: 7864. PMID 36543789 DOI: 10.1038/s41467-022-35586-7  0.352
2022 Palin AC, Alter G, Crotty S, Ellebedy AH, Lane MC, Lee FE, Locci M, Malaspina A, Mallia C, McElrath MJ, Pulendran B, Singh A, D'Souza MP. The persistence of memory: defining, engineering, and measuring vaccine durability. Nature Immunology. 23: 1665-1668. PMID 36456737 DOI: 10.1038/s41590-022-01359-z  0.326
2022 Alsoussi WB, Malladi SK, Zhou JQ, Liu Z, Ying B, Kim W, Schmitz AJ, Lei T, Horvath SC, Sturtz AJ, McIntire KM, Evavold B, Han F, Scheaffer SM, Fox IF, ... ... Ellebedy AH, et al. SARS-CoV-2 Omicron boosting induces de novo B cell response in humans. Biorxiv : the Preprint Server For Biology. PMID 36172127 DOI: 10.1101/2022.09.22.509040  0.508
2022 Gupta SL, Mantus G, Manning KE, Ellis M, Patel M, Ciric CR, Lu A, Turner JS, O'Halloran JA, Presti RM, Joshi DJ, Ellebedy AH, Anderson EJ, Rostad CA, Suthar MS, et al. Loss of Pfizer (BNT162b2) Vaccine-Induced Antibody Responses against the SARS-CoV-2 Omicron Variant in Adolescents and Adults. Journal of Virology. e0058222. PMID 35976000 DOI: 10.1128/jvi.00582-22  0.497
2022 Zimmerman O, Altman Doss AM, Kaplonek P, Liang CY, VanBlargan LA, Chen RE, Monroy JM, Wedner HJ, Kulczycki A, Mantia TL, O'Shaughnessy CC, Davis-Adams HG, Bertera HL, Adams LJ, Raju S, ... ... Ellebedy AH, et al. mRNA vaccine boosting enhances antibody responses against SARS-CoV-2 Omicron variant in individuals with antibody deficiency syndromes. Cell Reports. Medicine. 100653. PMID 35688161 DOI: 10.1016/j.xcrm.2022.100653  0.556
2022 Bamunuarachchi G, Harastani H, Rothlauf PW, Dai YN, Ellebedy A, Fremont D, Whelan SPJ, Wang D, Boon ACM. Detection of Bourbon Virus-Specific Serum Neutralizing Antibodies in Human Serum in Missouri, USA. Msphere. e0016422. PMID 35607948 DOI: 10.1128/msphere.00164-22  0.352
2022 Simon V, Kota V, Bloomquist RF, Hanley HB, Forgacs D, Pahwa S, Pallikkuth S, Miller LG, Schaenman J, Yeaman MR, Manthei D, Wolf J, Gaur AH, Estepp JH, Srivastava K, ... ... Ellebedy AH, et al. PARIS and SPARTA: Finding the Achilles' Heel of SARS-CoV-2. Msphere. e0017922. PMID 35586986 DOI: 10.1128/msphere.00179-22  0.485
2022 Altomare CG, Adelsberg DC, Carreno JM, Sapse IA, Amanat F, Ellebedy AH, Simon V, Krammer F, Bajic G. Structure of a Vaccine-Induced, Germline-Encoded Human Antibody Defines a Neutralizing Epitope on the SARS-CoV-2 Spike N-Terminal Domain. Mbio. e0358021. PMID 35467422 DOI: 10.1128/mbio.03580-21  0.514
2022 Yang MM, Taylor KE, Paez D, Carividi A, Demissie E, Pawar N, El-Qunni AA, McMorrow LE, Schriefer RE, Huang K, Kinnett B, Klebert M, Haile A, O'Halloran JA, Presti RM, ... ... Ellebedy AH, et al. Reactogenicity of the mRNA SARS-CoV-2 Vaccines Associates with Immunogenicity in Patients with Autoimmune and Inflammatory Disease. Arthritis Care & Research. PMID 35412029 DOI: 10.1002/acr.24894  0.441
2022 DeGrace MM, Ghedin E, Frieman MB, Krammer F, Grifoni A, Alisoltani A, Alter G, Amara RR, Baric RS, Barouch DH, Bloom JD, Bloyet LM, Bonenfant G, Boon ACM, Boritz EA, ... ... Ellebedy A, et al. Defining the risk of SARS-CoV-2 variants on immune protection. Nature. PMID 35361968 DOI: 10.1038/s41586-022-04690-5  0.722
2022 Teefey SA, Middleton WD, Turner JS, Ellebedy AH, Suessen T, Wallendorf M, O'Halloran JA, Presti R. SARS-CoV-2 mRNA Vaccination Causes Prolonged Increased Cortical Thickening and Vascularity in Ipsilateral Axillary Lymph Nodes. Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine. PMID 35257401 DOI: 10.1002/jum.15973  0.356
2022 Kim W, Zhou JQ, Horvath SC, Schmitz AJ, Sturtz AJ, Lei T, Liu Z, Kalaidina E, Thapa M, Alsoussi WB, Haile A, Klebert MK, Suessen T, Parra-Rodriguez L, Mudd PA, ... ... Ellebedy AH, et al. Germinal centre-driven maturation of B cell response to mRNA vaccination. Nature. PMID 35168246 DOI: 10.1038/s41586-022-04527-1  0.437
2021 Mudd PA, Minervina AA, Pogorelyy MV, Turner JS, Kim W, Kalaidina E, Petersen J, Schmitz AJ, Lei T, Haile A, Kirk AM, Mettelman RC, Crawford JC, Nguyen THO, Rowntree LC, ... ... Ellebedy AH, et al. SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans. Cell. PMID 35026152 DOI: 10.1016/j.cell.2021.12.026  0.343
2021 Laidlaw BJ, Ellebedy AH. The germinal centre B cell response to SARS-CoV-2. Nature Reviews. Immunology. 22: 7-18. PMID 34873279 DOI: 10.1038/s41577-021-00657-1  0.465
2021 Chen RE, Gorman MJ, Zhu DY, Carreño JM, Yuan D, VanBlargan LA, Burdess S, Lauffenburger DA, Kim W, Turner JS, Droit L, Handley SA, Chahin S, Deepak P, O'Halloran JA, ... ... Ellebedy AH, et al. Reduced antibody activity against SARS-CoV-2 B.1.617.2 Delta virus in serum of mRNA-vaccinated patients receiving Tumor Necrosis Factor-α inhibitors. Med (New York, N.Y.). PMID 34812429 DOI: 10.1016/j.medj.2021.11.004  0.445
2021 Kim W, Zhou JQ, Sturtz AJ, Horvath SC, Schmitz AJ, Lei T, Kalaidina E, Thapa M, Alsoussi WB, Haile A, Klebert MK, Suessen T, Parra-Rodriguez L, Mudd PA, Middleton WD, ... ... Ellebedy AH, et al. Germinal centre-driven maturation of B cell response to SARS-CoV-2 vaccination. Biorxiv : the Preprint Server For Biology. PMID 34751268 DOI: 10.1101/2021.10.31.466651  0.448
2021 Arunkumar GA, Bhavsar D, Li T, Strohmeier S, Chromikova V, Amanat F, Bunyatov M, Wilson PC, Ellebedy AH, Boons GJ, Simon V, de Vries RP, Krammer F. Functionality of the putative surface glycoproteins of the Wuhan spiny eel influenza virus. Nature Communications. 12: 6161. PMID 34697321 DOI: 10.1038/s41467-021-26409-2  0.475
2021 Tan J, O'Dell G, Hernandez MM, Sordillo EM, Kahn Z, Kriti D, van Bakel H, Ellebedy AH, Wilson PC, Simon V, Krammer F, McMahon M. Human anti-neuraminidase antibodies reduce airborne transmission of clinical influenza virus isolates in the guinea pig model. Journal of Virology. JVI0142121. PMID 34669506 DOI: 10.1128/JVI.01421-21  0.596
2021 Errico JM, Zhao H, Chen RE, Liu Z, Case JB, Ma M, Schmitz AJ, Rau MJ, Fitzpatrick JAJ, Shi PY, Diamond MS, Whelan SPJ, Ellebedy AH, Fremont DH. Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD. Cell Reports. 37: 109881. PMID 34655519 DOI: 10.1016/j.celrep.2021.109881  0.366
2021 Su W, Sia SF, Schmitz AJ, Bricker TL, Starr TN, Greaney AJ, Turner JS, Mohammed BM, Liu Z, Choy KT, Darling TL, Joshi A, Cheng KM, Wong AYL, Harastani HH, ... ... Ellebedy AH, et al. Neutralizing Monoclonal Antibodies That Target the Spike Receptor Binding Domain Confer Fc Receptor-Independent Protection against SARS-CoV-2 Infection in Syrian Hamsters. Mbio. e0239521. PMID 34517754 DOI: 10.1128/mBio.02395-21  0.428
2021 Schmitz AJ, Turner JS, Liu Z, Zhou JQ, Aziati ID, Chen RE, Joshi A, Bricker TL, Darling TL, Adelsberg DC, Altomare CG, Alsoussi WB, Case JB, VanBlargan LA, Lei T, ... ... Ellebedy AH, et al. A vaccine-induced public antibody protects against SARS-CoV-2 and emerging variants. Immunity. PMID 34464596 DOI: 10.1016/j.immuni.2021.08.013  0.728
2021 Deepak P, Kim W, Paley MA, Yang M, Carvidi AB, Demissie EG, El-Qunni AA, Haile A, Huang K, Kinnett B, Liebeskind MJ, Liu Z, McMorrow LE, Paez D, Pawar N, ... ... Ellebedy AH, et al. Effect of Immunosuppression on the Immunogenicity of mRNA Vaccines to SARS-CoV-2 : A Prospective Cohort Study. Annals of Internal Medicine. PMID 34461029 DOI: 10.7326/M21-1757  0.388
2021 Reynolds D, Vazquez Guillamet C, Day A, Borcherding N, Vazquez Guillamet R, Choreño-Parra JA, House SL, O'Halloran JA, Zúñiga J, Ellebedy AH, Byers DE, Mudd PA. Comprehensive Immunologic Evaluation of Bronchoalveolar Lavage Samples from Human Patients with Moderate and Severe Seasonal Influenza and Severe COVID-19. Journal of Immunology (Baltimore, Md. : 1950). PMID 34348975 DOI: 10.4049/jimmunol.2100294  0.382
2021 Amanat F, Thapa M, Lei T, Ahmed SMS, Adelsberg DC, Carreño JM, Strohmeier S, Schmitz AJ, Zafar S, Zhou JQ, Rijnink W, Alshammary H, Borcherding N, Reiche AG, Srivastava K, ... ... Ellebedy AH, et al. SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2. Cell. PMID 34192529 DOI: 10.1016/j.cell.2021.06.005  0.561
2021 Turner JS, O'Halloran JA, Kalaidina E, Kim W, Schmitz AJ, Zhou JQ, Lei T, Thapa M, Chen RE, Case JB, Amanat F, Rauseo AM, Haile A, Xie X, Klebert MK, ... ... Ellebedy AH, et al. SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses. Nature. PMID 34182569 DOI: 10.1038/s41586-021-03738-2  0.462
2021 Chen RE, Winkler ES, Case JB, Aziati ID, Bricker TL, Joshi A, Darling TL, Ying B, Errico JM, Shrihari S, VanBlargan LA, Xie X, Gilchuk P, Zost SJ, Droit L, ... ... Ellebedy AH, et al. In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains. Nature. PMID 34153975 DOI: 10.1038/s41586-021-03720-y  0.327
2021 Turner JS, Kim W, Kalaidina E, Goss CW, Rauseo AM, Schmitz AJ, Hansen L, Haile A, Klebert MK, Pusic I, O'Halloran JA, Presti RM, Ellebedy AH. SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans. Nature. PMID 34030176 DOI: 10.1038/s41586-021-03647-4  0.302
2021 Diamond M, Chen R, Winkler E, Case J, Aziati I, Bricker T, Joshi A, Darling T, Ying B, Errico J, Shrihari S, VanBlargan L, Xie X, Gilchuk P, Zost S, ... ... Ellebedy A, et al. In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains. Research Square. PMID 34013259 DOI: 10.21203/rs.3.rs-448370/v1  0.326
2021 Deepak P, Kim W, Paley MA, Yang M, Carvidi AB, El-Qunni AA, Haile A, Huang K, Kinnett B, Liebeskind MJ, Liu Z, McMorrow LE, Paez D, Perantie DC, Schriefer RE, ... ... Ellebedy AH, et al. Glucocorticoids and B Cell Depleting Agents Substantially Impair Immunogenicity of mRNA Vaccines to SARS-CoV-2. Medrxiv : the Preprint Server For Health Sciences. PMID 33851176 DOI: 10.1101/2021.04.05.21254656  0.416
2021 Schmitz AJ, Turner JS, Liu Z, Aziati ID, Chen RE, Joshi A, Bricker TL, Darling TL, Adelsberg DC, Alsoussi WB, Case JB, Lei T, Thapa M, Amanat F, O'Halloran JA, ... ... Ellebedy AH, et al. A public vaccine-induced human antibody protects against SARS-CoV-2 and emerging variants. Biorxiv : the Preprint Server For Biology. PMID 33791696 DOI: 10.1101/2021.03.24.436864  0.585
2021 Amanat F, Thapa M, Lei T, Ahmed SMS, Adelsberg DC, Carreno JM, Strohmeier S, Schmitz AJ, Zafar S, Zhou JQ, Rijnink W, Alshammary H, Borcherding N, Reiche AG, Srivastava K, ... ... Ellebedy AH, et al. The plasmablast response to SARS-CoV-2 mRNA vaccination is dominated by non-neutralizing antibodies that target both the NTD and the RBD. Medrxiv : the Preprint Server For Health Sciences. PMID 33758878 DOI: 10.1101/2021.03.07.21253098  0.563
2021 Chen RE, Zhang X, Case JB, Winkler ES, Liu Y, VanBlargan LA, Liu J, Errico JM, Xie X, Suryadevara N, Gilchuk P, Zost SJ, Tahan S, Droit L, Turner JS, ... ... Ellebedy AH, et al. Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies. Nature Medicine. PMID 33664494 DOI: 10.1038/s41591-021-01294-w  0.511
2021 Diamond M, Chen R, Xie X, Case J, Zhang X, VanBlargan L, Liu Y, Liu J, Errico J, Winkler E, Suryadevara N, Tahan S, Turner J, Kim W, Schmitz A, ... ... Ellebedy A, et al. SARS-CoV-2 variants show resistance to neutralization by many monoclonal and serum-derived polyclonal antibodies. Research Square. PMID 33594356 DOI: 10.21203/rs.3.rs-228079/v1  0.512
2021 Liu Z, VanBlargan LA, Bloyet LM, Rothlauf PW, Chen RE, Stumpf S, Zhao H, Errico JM, Theel ES, Liebeskind MJ, Alford B, Buchser WJ, Ellebedy AH, Fremont DH, Diamond MS, et al. Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization. Cell Host & Microbe. PMID 33535027 DOI: 10.1016/j.chom.2021.01.014  0.363
2021 Han J, Schmitz AJ, Richey ST, Dai YN, Turner HL, Mohammed BM, Fremont DH, Ellebedy AH, Ward AB. Polyclonal epitope mapping reveals temporal dynamics and diversity of human antibody responses to H5N1 vaccination. Cell Reports. 34: 108682. PMID 33503432 DOI: 10.1016/j.celrep.2020.108682  0.623
2020 Liu Z, VanBlargan LA, Rothlauf PW, Bloyet LM, Chen RE, Stumpf S, Zhao H, Errico JM, Theel ES, Ellebedy AH, Fremont DH, Diamond MS, Whelan SPJ. Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization. Biorxiv : the Preprint Server For Biology. PMID 33442690 DOI: 10.1101/2020.11.06.372037  0.351
2020 Ellebedy A, Turner J, Kim W, Kalaidina E, Goss C, Rauseo A, Schmitz A, Hansen L, Haile A, Klebert M, Pusic I, O'Halloran J, Presti R. SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans. Research Square. PMID 33398264 DOI: 10.21203/rs.3.rs-132821/v1  0.451
2020 Mudd PA, Crawford JC, Turner JS, Souquette A, Reynolds D, Bender D, Bosanquet JP, Anand NJ, Striker DA, Martin RS, Boon ACM, House SL, Remy KE, Hotchkiss RS, Presti RM, ... ... Ellebedy AH, et al. Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm. Science Advances. PMID 33187979 DOI: 10.1126/sciadv.abe3024  0.326
2020 Koutsakos M, Ellebedy AH. The rise and fall of bone marrow plasma cells after influenza vaccination. Immunology and Cell Biology. PMID 33167072 DOI: 10.1111/imcb.12417  0.413
2020 Linderman SL, Ellebedy AH, Davis C, Eberhardt CS, Antia R, Ahmed R, Zarnitsyna VI. Influenza Immunization in the Context of Preexisting Immunity. Cold Spring Harbor Perspectives in Medicine. PMID 32988981 DOI: 10.1101/cshperspect.a040964  0.637
2020 Madsen A, Dai YN, McMahon M, Schmitz AJ, Turner JS, Tan J, Lei T, Alsoussi WB, Strohmeier S, Amor M, Mohammed BM, Mudd PA, Simon V, Cox RJ, Fremont DH, ... ... Ellebedy AH, et al. Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective. Immunity. PMID 32976769 DOI: 10.1016/j.immuni.2020.08.015  0.529
2020 McMahon M, Strohmeier S, Rajendran M, Capuano C, Ellebedy AH, Wilson PC, Krammer F. Correctly folded - but not necessarily functional - influenza virus neuraminidase is required to induce protective antibody responses in mice. Vaccine. PMID 32943267 DOI: 10.1016/J.Vaccine.2020.08.067  0.629
2020 Turner JS, Zhou JQ, Han J, Schmitz AJ, Rizk AA, Alsoussi WB, Lei T, Amor M, McIntire KM, Meade P, Strohmeier S, Brent RI, Richey ST, Haile A, Yang YR, ... ... Ellebedy AH, et al. Human germinal centres engage memory and naive B cells after influenza vaccination. Nature. PMID 32866963 DOI: 10.1038/S41586-020-2711-0  0.664
2020 Remy KE, Mazer M, Striker DA, Ellebedy AH, Walton AH, Unsinger J, Blood TM, Mudd PA, Yi DJ, Mannion DA, Osborne DF, Martin RS, Anand NJ, Bosanquet JP, Blood J, et al. Severe immunosuppression and not a cytokine storm characterize COVID-19 infections. Jci Insight. PMID 32687484 DOI: 10.1172/Jci.Insight.140329  0.333
2020 Ellebedy AH, Nachbagauer R, Jackson KJL, Dai YN, Han J, Alsoussi WB, Davis CW, Stadlbauer D, Rouphael N, Chromikova V, McCausland M, Chang CY, Cortese M, Bower M, Chennareddy C, et al. Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans. Proceedings of the National Academy of Sciences of the United States of America. PMID 32661157 DOI: 10.1073/Pnas.1906613117  0.689
2020 Carnathan DG, Kaushik K, Ellebedy AH, Enemuo CA, Gebru EH, Dhadvai P, Rasheed MAU, Pauthner MG, Ozorowski G, Ahmed R, Burton DR, Ward AB, Silvestri G, Crotty S, Locci M. Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers. Frontiers in Immunology. 11: 1213. PMID 32612608 DOI: 10.3389/Fimmu.2020.01213  0.447
2020 Alsoussi WB, Turner JS, Case JB, Zhao H, Schmitz AJ, Zhou JQ, Chen RE, Lei T, Rizk AA, McIntire KM, Winkler ES, Fox JM, Kafai NM, Thackray LB, Hassan AO, ... ... Ellebedy AH, et al. A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection. Journal of Immunology (Baltimore, Md. : 1950). PMID 32591393 DOI: 10.4049/Jimmunol.2000583  0.434
2020 Hassan AO, Case JB, Winkler ES, Thackray LB, Kafai NM, Bailey AL, McCune BT, Fox JM, Chen RE, Alsoussi WB, Turner JS, Schmitz AJ, Lei T, Shrihari S, Keeler SP, ... ... Ellebedy AH, et al. A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies. Cell. PMID 32553273 DOI: 10.1016/J.Cell.2020.06.011  0.458
2020 Mudd PA, Crawford JC, Turner JS, Souquette A, Reynolds D, Bender D, Bosanquet JP, Anand NJ, Striker DA, Martin RS, Boon ACM, House SL, Remy KE, Hotchkiss RS, Presti RM, ... ... Ellebedy AH, et al. Targeted Immunosuppression Distinguishes COVID-19 from Influenza in Moderate and Severe Disease. Medrxiv : the Preprint Server For Health Sciences. PMID 32511543 DOI: 10.1101/2020.05.28.20115667  0.381
2020 Turner JS, Lei T, Schmitz AJ, Day A, Choreño-Parra JA, Jiménez-Alvarez L, Cruz-Lagunas A, House SL, Zúñiga J, Ellebedy AH, Mudd PA. Impaired Cellular Immune Responses During the First Week of Severe Acute Influenza Infection. The Journal of Infectious Diseases. PMID 32369589 DOI: 10.1093/Infdis/Jiaa226  0.43
2020 Turner JS, Lei T, Schmitz AJ, Day A, Choreño-Parra JA, Jiménez-Alvarez L, Cruz-Lagunas A, House SL, Zúñiga J, Ellebedy AH, Mudd PA. Impaired Cellular Immune Responses During the First Week of Severe Acute Influenza Infection. The Journal of Infectious Diseases. PMID 32369589 DOI: 10.1093/Infdis/Jiaa226  0.43
2020 Bradley T, Kuraoka M, Yeh CH, Tian M, Chen H, Cain DW, Chen X, Cheng C, Ellebedy AH, Parks R, Barr M, Sutherland LL, Scearce RM, Bowman CM, Bouton-Verville H, et al. Immune checkpoint modulation enhances HIV-1 antibody induction. Nature Communications. 11: 948. PMID 32075963 DOI: 10.1038/S41467-020-14670-W  0.451
2019 Stadlbauer D, Zhu X, McMahon M, Turner JS, Wohlbold TJ, Schmitz AJ, Strohmeier S, Yu W, Nachbagauer R, Mudd PA, Wilson IA, Ellebedy AH, Krammer F. Broadly protective human antibodies that target the active site of influenza virus neuraminidase. Science (New York, N.Y.). 366: 499-504. PMID 31649200 DOI: 10.1126/Science.Aay0678  0.694
2019 Davis CW, Jackson KJL, McElroy AK, Halfmann P, Huang J, Chennareddy C, Piper AE, Leung Y, Albariño CG, Crozier I, Ellebedy AH, Sidney J, Sette A, Yu T, Nielsen SCA, et al. Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection. Cell. PMID 31104840 DOI: 10.1016/J.Cell.2019.04.036  0.536
2019 Tesini BL, Kanagaiah P, Wang J, Hahn M, Halliley JL, Chaves FA, Nguyen PQT, Nogales A, DeDiego ML, Anderson CS, Ellebedy AH, Strohmeier S, Krammer F, Yang H, Bandyopadhyay S, et al. Broad hemagglutinin-specific memory B cell expansion by seasonal influenza virus infection reflects early-life imprinting and adaptation to the infecting virus. Journal of Virology. PMID 30728266 DOI: 10.1128/Jvi.00169-19  0.613
2019 Mudd P, Lei T, Ellebedy A. 247EMF Impaired Human Influenza-Specific CD8+ T Cell Responses During Acute Symptomatic Seasonal Influenza Infection Annals of Emergency Medicine. 74: S97. DOI: 10.1016/j.annemergmed.2019.08.415  0.429
2018 Ellebedy AH. Immunizing the Immune: Can We Overcome Influenza's Most Formidable Challenge? Vaccines. 6. PMID 30248996 DOI: 10.3390/Vaccines6040068  0.714
2018 Nachbagauer R, Shore D, Yang H, Johnson SK, Gabbard JD, Tompkins SM, Wrammert J, Wilson PC, Stevens J, Ahmed R, Krammer F, Ellebedy AH. Broadly-reactive human monoclonal antibodies elicited following pandemic H1N1 influenza virus exposure protect mice from highly pathogenic H5N1 challenge. Journal of Virology. PMID 29899095 DOI: 10.1128/JVI.00949-18  0.565
2018 Nachbagauer R, Shore D, Yang H, Johnson SK, Gabbard JD, Tompkins SM, Wrammert J, Wilson PC, Stevens J, Ahmed R, Krammer F, Ellebedy AH. Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge. Journal of Virology. 92. DOI: 10.2210/Pdb6B3M/Pdb  0.627
2017 McElroy AK, Akondy RS, Harmon JR, Ellebedy AH, Cannon D, Klena JD, Sidney J, Sette A, Mehta AK, Kraft CS, Lyon MG, Varkey JB, Ribner BS, Nichol ST, Spiropoulou CF. A Case of Human Lassa Virus Infection With Robust Acute T-Cell Activation and Long-Term Virus-Specific T-Cell Responses. The Journal of Infectious Diseases. 215: 1862-1872. PMID 28863472 DOI: 10.1093/Infdis/Jix201  0.436
2017 Czakó R, Vogel L, Lamirande EW, Bock KW, Moore IN, Ellebedy AH, Ahmed R, Mehle A, Subbarao K. In Vivo Imaging of Influenza Virus Infection in Immunized Mice. Mbio. 8. PMID 28559489 DOI: 10.1128/Mbio.00714-17  0.642
2017 Holthausen DJ, Lee SH, Kumar VT, Bouvier NM, Krammer F, Ellebedy AH, Wrammert J, Lowen AC, George S, Pillai MR, Jacob J. An Amphibian Host Defense Peptide Is Virucidal for Human H1 Hemagglutinin-Bearing Influenza Viruses. Immunity. 46: 587-595. PMID 28423338 DOI: 10.1016/J.Immuni.2017.03.018  0.613
2016 Ellebedy AH, Jackson KJ, Kissick HT, Nakaya HI, Davis CW, Roskin KM, McElroy AK, Oshansky CM, Elbein R, Thomas S, Lyon GM, Spiropoulou CF, Mehta AK, Thomas PG, Boyd SD, et al. Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination. Nature Immunology. PMID 27525369 DOI: 10.1038/Ni.3533  0.662
2016 Zarnitsyna VI, Lavine J, Ellebedy A, Ahmed R, Antia R. Multi-epitope Models Explain How Pre-existing Antibodies Affect the Generation of Broadly Protective Responses to Influenza. Plos Pathogens. 12: e1005692. PMID 27336297 DOI: 10.1371/Journal.Ppat.1005692  0.663
2016 Tesini B, Halliley J, Ellebedy A, Kanagaiah P, Anderson C, Dediego M, Wang J, Zand M, Ahmed R, Krammer F, Treanor JJ, Topham D, Sangster M. Natural H3N2 influenza A Infection in Humans Expands Memory B Cells Specific for the Hemagglutinin Stalk Domain Open Forum Infectious Diseases. 3. DOI: 10.1093/Ofid/Ofw172.1742  0.498
2016 Ellebedy AH, Ahmed R. Antiviral Vaccines: Challenges and Advances The Vaccine Book: Second Edition. 283-310. DOI: 10.1016/B978-0-12-802174-3.00015-1  0.529
2015 Zarnitsyna VI, Ellebedy AH, Davis C, Jacob J, Ahmed R, Antia R. Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 370. PMID 26194761 DOI: 10.1098/Rstb.2014.0248  0.554
2015 McElroy AK, Akondy RS, Davis CW, Ellebedy AH, Mehta AK, Kraft CS, Lyon GM, Ribner BS, Varkey J, Sidney J, Sette A, Campbell S, Ströher U, Damon I, Nichol ST, et al. Human Ebola virus infection results in substantial immune activation. Proceedings of the National Academy of Sciences of the United States of America. 112: 4719-24. PMID 25775592 DOI: 10.1073/Pnas.1502619112  0.474
2015 Chiu C, Ellebedy AH, Wrammert J, Ahmed R. B cell responses to influenza infection and vaccination. Current Topics in Microbiology and Immunology. 386: 381-98. PMID 25193634 DOI: 10.1007/82_2014_425  0.692
2014 Linderman SL, Chambers BS, Zost SJ, Parkhouse K, Li Y, Herrmann C, Ellebedy AH, Carter DM, Andrews SF, Zheng NY, Huang M, Huang Y, Strauss D, Shaz BH, Hodinka RL, et al. Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013-2014 influenza season. Proceedings of the National Academy of Sciences of the United States of America. 111: 15798-803. PMID 25331901 DOI: 10.1073/Pnas.1409171111  0.59
2014 Ellebedy AH, Krammer F, Li GM, Miller MS, Chiu C, Wrammert J, Chang CY, Davis CW, McCausland M, Elbein R, Edupuganti S, Spearman P, Andrews SF, Wilson PC, García-Sastre A, et al. Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans. Proceedings of the National Academy of Sciences of the United States of America. 111: 13133-8. PMID 25157133 DOI: 10.1073/Pnas.1414070111  0.677
2012 Ellebedy AH, Ahmed R. Re-engaging cross-reactive memory B cells: the influenza puzzle. Frontiers in Immunology. 3: 53. PMID 22566934 DOI: 10.3389/Fimmu.2012.00053  0.713
2011 Araki K, Ellebedy AH, Ahmed R. TOR in the immune system. Current Opinion in Cell Biology. 23: 707-15. PMID 21925855 DOI: 10.1016/J.Ceb.2011.08.006  0.335
2011 Valkenburg SA, Rutigliano JA, Ellebedy AH, Doherty PC, Thomas PG, Kedzierska K. Immunity to seasonal and pandemic influenza A viruses. Microbes and Infection / Institut Pasteur. 13: 489-501. PMID 21295153 DOI: 10.1016/J.Micinf.2011.01.007  0.567
2011 Ellebedy AH, Lupfer C, Ghoneim HE, DeBeauchamp J, Kanneganti TD, Webby RJ. Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59. Proceedings of the National Academy of Sciences of the United States of America. 108: 2927-32. PMID 21270336 DOI: 10.1073/Pnas.1012455108  0.721
2011 Ellebedy AH, Ducatez MF, Duan S, Stigger-Rosser E, Rubrum AM, Govorkova EA, Webster RG, Webby RJ. Impact of prior seasonal influenza vaccination and infection on pandemic A (H1N1) influenza virus replication in ferrets. Vaccine. 29: 3335-9. PMID 20840835 DOI: 10.1016/J.Vaccine.2010.08.067  0.755
2010 Marcelin G, Bland HM, Negovetich NJ, Sandbulte MR, Ellebedy AH, Webb AD, Griffin YS, DeBeauchamp JL, McElhaney JE, Webby RJ. Inactivated seasonal influenza vaccines increase serum antibodies to the neuraminidase of pandemic influenza A(H1N1) 2009 virus in an age-dependent manner. The Journal of Infectious Diseases. 202: 1634-8. PMID 20979454 DOI: 10.1086/657084  0.734
2010 Ellebedy AH, Fabrizio TP, Kayali G, Oguin TH, Brown SA, Rehg J, Thomas PG, Webby RJ. Contemporary seasonal influenza A (H1N1) virus infection primes for a more robust response to split inactivated pandemic influenza A (H1N1) Virus vaccination in ferrets. Clinical and Vaccine Immunology : Cvi. 17: 1998-2006. PMID 20962210 DOI: 10.1128/Cvi.00247-10  0.761
2010 Kim JK, Kayali G, Walker D, Forrest HL, Ellebedy AH, Griffin YS, Rubrum A, Bahgat MM, Kutkat MA, Ali MA, Aldridge JR, Negovetich NJ, Krauss S, Webby RJ, Webster RG. Puzzling inefficiency of H5N1 influenza vaccines in Egyptian poultry. Proceedings of the National Academy of Sciences of the United States of America. 107: 11044-9. PMID 20534457 DOI: 10.1073/Pnas.1006419107  0.759
2010 Marcelin G, Bland HM, Negovetich NJ, Sandbulte MR, Ellebedy AH, Webb AD, Griffin YS, DeBeauchamp JL, McElhaney JE, Webby RJ. Inactivated season influenza vaccines increase serum antibodies to the neuraminidase of pandemic H1N1 2009 influenza virus in an age dependent manner F1000research. 1. DOI: 10.7490/F1000Research.609.1  0.725
2009 Ellebedy AH, Webby RJ. Influenza vaccines. Vaccine. 27: D65-8. PMID 19837290 DOI: 10.1016/j.vaccine.2009.08.038  0.7
2009 Thomas PG, Dash P, Aldridge JR, Ellebedy AH, Reynolds C, Funk AJ, Martin WJ, Lamkanfi M, Webby RJ, Boyd KL, Doherty PC, Kanneganti TD. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity. 30: 566-75. PMID 19362023 DOI: 10.1016/J.Immuni.2009.02.006  0.598
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