cached image

Richard Klausner, M.D. - Publications

Affiliations: 
NIH/NCI 
Area:
cell biology and metabolism
Website:
http://womenscancerresearchfund.org/81/richard-d-klausner-m-d/

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Pjura WJ, Kleinfeld AM, Klausner RD, Karnovsky MJ. Fatty Acid perturbation of a membrane protein-lipid interaction: a terbium (tb) study. Biophysical Journal. 37: 69-71. PMID 19431507 DOI: 10.1016/S0006-3495(82)84604-3  0.472
2002 Brower CS, Sato S, Tomomori-Sato C, Kamura T, Pause A, Stearman R, Klausner RD, Malik S, Lane WS, Sorokina I, Roeder RG, Conaway JW, Conaway RC. Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase. Proceedings of the National Academy of Sciences of the United States of America. 99: 10353-8. PMID 12149480 DOI: 10.1073/Pnas.162424199  0.633
2002 Maranchie JK, Vasselli JR, Riss J, Bonifacino JS, Linehan WM, Klausner RD. The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma. Cancer Cell. 1: 247-55. PMID 12086861 DOI: 10.1016/S1535-6108(02)00044-2  0.495
2001 de Paulsen N, Brychzy A, Fournier MC, Klausner RD, Gnarra JR, Pause A, Lee S. Role of transforming growth factor-alpha in von Hippel--Lindau (VHL)(-/-) clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 98: 1387-92. PMID 11171960 DOI: 10.1073/Pnas.031587498  0.651
1999 Iwai K, Yamanaka K, Kamura T, Minato N, Conaway RC, Conaway JW, Klausner RD, Pause A. Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex. Proceedings of the National Academy of Sciences of the United States of America. 96: 12436-41. PMID 10535940 DOI: 10.1073/Pnas.96.22.12436  0.623
1999 Pause A, Peterson B, Schaffar G, Stearman R, Klausner RD. Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein. Proceedings of the National Academy of Sciences of the United States of America. 96: 9533-8. PMID 10449727 DOI: 10.1073/Pnas.96.17.9533  0.619
1999 Lee S, Neumann M, Stearman R, Stauber R, Pause A, Pavlakis GN, Klausner RD. Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein. Molecular and Cellular Biology. 19: 1486-97. PMID 9891082 DOI: 10.1128/Mcb.19.2.1486  0.618
1998 Pause A, Lee S, Lonergan KM, Klausner RD. The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal. Proceedings of the National Academy of Sciences of the United States of America. 95: 993-8. PMID 9448273 DOI: 10.1073/Pnas.95.3.993  0.606
1997 Pause A, Lee S, Worrell RA, Chen DY, Burgess WH, Linehan WM, Klausner RD. The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins. Proceedings of the National Academy of Sciences of the United States of America. 94: 2156-61. PMID 9122164 DOI: 10.1073/Pnas.94.6.2156  0.639
1996 Pause A, Aso T, Linehan WM, Conaway JW, Conaway RC, Klausner RD. Interaction of von Hippel-Lindau tumor suppressor gene product with elongin. Methods in Enzymology. 274: 436-41. PMID 8902823 DOI: 10.1016/S0076-6879(96)74035-1  0.615
1996 Radhakrishna H, Klausner RD, Donaldson JG. Aluminum fluoride stimulates surface protrusions in cells overexpressing the ARF6 GTPase. The Journal of Cell Biology. 134: 935-47. PMID 8769418 DOI: 10.1083/Jcb.134.4.935  0.301
1996 Ooi CE, Rabinovich E, Dancis A, Bonifacino JS, Klausner RD. Copper-dependent degradation of the Saccharomyces cerevisiae plasma membrane copper transporter Ctr1p in the apparent absence of endocytosis. The Embo Journal. 15: 3515-23. PMID 8670854 DOI: 10.1002/J.1460-2075.1996.Tb00720.X  0.502
1996 Gnarra JR, Duan DR, Weng Y, Humphrey JS, Chen DY, Lee S, Pause A, Dudley CF, Latif F, Kuzmin I, Schmidt L, Duh FM, Stackhouse T, Chen F, Kishida T, ... ... Klausner RD, et al. Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma. Biochimica Et Biophysica Acta. 1242: 201-10. PMID 8603073 DOI: 10.1016/0304-419X(95)00012-5  0.553
1995 Duan DR, Pause A, Burgess WH, Aso T, Chen DY, Garrett KP, Conaway RC, Conaway JW, Linehan WM, Klausner RD. Inhibition of transcription elongation by the VHL tumor suppressor protein. Science (New York, N.Y.). 269: 1402-6. PMID 7660122 DOI: 10.1126/Science.7660122  0.611
1993 Lankford SP, Cosson P, Bonifacino JS, Klausner RD. Transmembrane domain length affects charge-mediated retention and degradation of proteins within the endoplasmic reticulum. The Journal of Biological Chemistry. 268: 4814-20. PMID 8444858  0.556
1992 Klausner RD, Donaldson JG, Lippincott-Schwartz J. Brefeldin A: insights into the control of membrane traffic and organelle structure. The Journal of Cell Biology. 116: 1071-80. PMID 1740466 DOI: 10.1083/Jcb.116.5.1071  0.48
1992 Letourneur F, Klausner RD. A novel di-leucine motif and a tyrosine-based motif independently mediate lysosomal targeting and endocytosis of CD3 chains Cell. 69: 1143-1157. PMID 1535555 DOI: 10.1016/0092-8674(92)90636-Q  0.342
1992 Rutledge T, Cosson P, Manolios N, Bonifacino JS, Klausner RD. Transmembrane helical interactions: zeta chain dimerization and functional association with the T cell antigen receptor. The Embo Journal. 11: 3245-54. PMID 1505516 DOI: 10.1002/J.1460-2075.1992.Tb05402.X  0.564
1991 Orci L, Tagaya M, Amherdt M, Perrelet A, Donaldson JG, Lippincott-Schwartz J, Klausner RD, Rothman JE. Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae. Cell. 64: 1183-95. PMID 2004424 DOI: 10.1016/0092-8674(91)90273-2  0.466
1991 Donaldson JG, Lippincott-Schwartz J, Klausner RD. Guanine nucleotides modulate the effects of brefeldin A in semipermeable cells: regulation of the association of a 110-kD peripheral membrane protein with the Golgi apparatus. The Journal of Cell Biology. 112: 579-88. PMID 1993732 DOI: 10.1083/Jcb.112.4.579  0.536
1991 Donaldson JG, Kahn RA, Lippincott-Schwartz J, Klausner RD. Binding of ARF and beta-COP to Golgi membranes: possible regulation by a trimeric G protein. Science (New York, N.Y.). 254: 1197-9. PMID 1957170 DOI: 10.1126/Science.1957170  0.511
1991 Bonifacino JS, Cosson P, Shah N, Klausner RD. Role of potentially charged transmembrane residues in targeting proteins for retention and degradation within the endoplasmic reticulum. The Embo Journal. 10: 2783-93. PMID 1915263 DOI: 10.1002/J.1460-2075.1991.Tb07827.X  0.549
1991 Hsu VW, Yuan LC, Nuchtern JG, Lippincott-Schwartz J, Hammerling GJ, Klausner RD. A recycling pathway between the endoplasmic reticulum and the Golgi apparatus for retention of unassembled MHC class I molecules. Nature. 352: 441-4. PMID 1861723 DOI: 10.1038/352441A0  0.484
1991 Minami Y, Stafford FJ, Lippincott-Schwartz J, Yuan LC, Klausner RD. Novel redistribution of an intracellular pool of CD45 accompanies T cell activation. The Journal of Biological Chemistry. 266: 9222-30. PMID 1851171  0.533
1991 Lippincott-Schwartz J, Glickman J, Donaldson JG, Robbins J, Kreis TE, Seamon KB, Sheetz MP, Klausner RD. Forskolin inhibits and reverses the effects of brefeldin A on Golgi morphology by a cAMP-independent mechanism. The Journal of Cell Biology. 112: 567-77. PMID 1847146 DOI: 10.1083/Jcb.112.4.567  0.509
1991 Letourneur F, Klausner RD. T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor ζ family proteins Proceedings of the National Academy of Sciences of the United States of America. 88: 8905-8909. PMID 1833767  0.367
1991 Manolios N, Letourneur F, Bonifacino JS, Klausner RD. Pairwise, cooperative and inhibitory interactions describe the assembly and probable structure of the T-cell antigen receptor. The Embo Journal. 10: 1643-51. PMID 1828760 DOI: 10.1002/J.1460-2075.1991.Tb07687.X  0.554
1991 Cosson P, Lankford SP, Bonifacino JS, Klausner RD. Membrane protein association by potential intramembrane charge pairs. Nature. 351: 414-6. PMID 1827877 DOI: 10.1038/351414A0  0.555
1991 Lippincott-Schwartz J, Yuan L, Tipper C, Amherdt M, Orci L, Klausner RD. Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic. Cell. 67: 601-16. PMID 1682055 DOI: 10.1016/0092-8674(91)90534-6  0.509
1991 Suzuki CK, Bonifacino JS, Lin AY, Davis MM, Klausner RD. Regulating the retention of T-cell receptor alpha chain variants within the endoplasmic reticulum: Ca(2+)-dependent association with BiP. The Journal of Cell Biology. 114: 189-205. PMID 1649196 DOI: 10.1083/Jcb.114.2.189  0.527
1990 Bonifacino JS, Suzuki CK, Klausner RD. A peptide sequence confers retention and rapid degradation in the endoplasmic reticulum. Science (New York, N.Y.). 247: 79-82. PMID 2294595 DOI: 10.1126/Science.2294595  0.547
1990 Donaldson JG, Lippincott-Schwartz J, Bloom GS, Kreis TE, Klausner RD. Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action. The Journal of Cell Biology. 111: 2295-306. PMID 2277061 DOI: 10.1083/Jcb.111.6.2295  0.512
1990 Klausner RD, Lippincott-Schwartz J, Bonifacino JS. The T cell antigen receptor: insights into organelle biology. Annual Review of Cell Biology. 6: 403-31. PMID 2275818 DOI: 10.1146/Annurev.Cb.06.110190.002155  0.637
1990 Bonifacino JS, Cosson P, Klausner RD. Colocalized transmembrane determinants for ER degradation and subunit assembly explain the intracellular fate of TCR chains. Cell. 63: 503-13. PMID 2225064 DOI: 10.1016/0092-8674(90)90447-M  0.568
1990 Orloff DG, Ra C, Frank SJ, Klausner RD, Kinet JP. Family of disulphide-linked dimers containing the ζ and η chains of the T-cell receptor and the γ chain of Fc receptors Nature. 347: 189-191. PMID 2203969 DOI: 10.1038/347189A0  0.346
1990 Samelson LE, Phillips AF, Luong ET, Klausner RD. Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor Proceedings of the National Academy of Sciences of the United States of America. 87: 4358-4362. PMID 2190221  0.322
1990 Ashwell JD, Klausner RD. Genetic and mutational analysis of the T-cell antigen receptor Annual Review of Immunology. 8: 139-167. PMID 2188661  0.317
1990 Lippincott-Schwartz J, Donaldson JG, Schweizer A, Berger EG, Hauri HP, Yuan LC, Klausner RD. Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin A suggests an ER recycling pathway. Cell. 60: 821-36. PMID 2178778 DOI: 10.1016/0092-8674(90)90096-W  0.509
1990 Frank SJ, Samelson LE, Klausner RD. The structure and signalling functions of the invariant T cell receptor components Seminars in Immunology. 2: 89-97. PMID 2151801  0.331
1990 Manolios N, Bonifacino JS, Klausner RD. Transmembrane helical interactions and the assembly of the T cell receptor complex. Science (New York, N.Y.). 249: 274-7. PMID 2142801 DOI: 10.1126/Science.2142801  0.613
1990 Antusch D, Bonifacino JS, Burgess WH, Klausner RD. The T cell receptor-associated protein is proteolytically cleaved in a pre-Golgi compartment. Journal of Immunology (Baltimore, Md. : 1950). 145: 885-90. PMID 2142711  0.583
1990 Bonifacino JS, McCarthy SA, Maguire JE, Nakayama T, Singer DS, Klausner RD, Singer A. Novel post-translational regulation of TCR expression in CD4+CD8+ thymocytes influenced by CD4. Nature. 344: 247-51. PMID 1690353 DOI: 10.1038/344247A0  0.465
1990 Klausner RD, Lippincott-Schwartz J, Bonifacino JS. Chapter 4 Architectural Editing: Regulating the Surface Expression of the Multicomponent T-Cell Antigen Receptor Current Topics in Membranes and Transport. 36: 31-51. DOI: 10.1016/S0070-2161(08)60166-5  0.669
1989 Nuchtern JG, Bonifacino JS, Biddison WE, Klausner RD. Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation. Nature. 339: 223-6. PMID 2785645 DOI: 10.1038/339223A0  0.545
1989 Orloff DG, Frank SJ, Robey FA, Weissman AM, Klausner RD. Biochemical characterization of the η chain of the T-cell receptor. A unique subunit related to ξ Journal of Biological Chemistry. 264: 14812-14817. PMID 2768241  0.347
1989 Klausner RD, Weissman AM, Baniyash M, Bonifacino JS, Samelson LE. The role of the zeta chain in the expression, structure and function of the T cell receptor. Advances in Experimental Medicine and Biology. 254: 21-4. PMID 2683606 DOI: 10.1007/978-1-4757-5803-0_3  0.566
1989 Bonifacino JS, Suzuki CK, Lippincott-Schwartz J, Weissman AM, Klausner RD. Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assembly. The Journal of Cell Biology. 109: 73-83. PMID 2663883 DOI: 10.1083/Jcb.109.1.73  0.651
1989 Weissman AM, Bonifacino JS, Klausner RD, Samelson LE, O'Shea JJ. T cell antigen receptor: structure, assembly and function. The Year in Immunology. 4: 74-93. PMID 2648706  0.513
1989 Lippincott-Schwartz J, Yuan LC, Bonifacino JS, Klausner RD. Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER. Cell. 56: 801-13. PMID 2647301 DOI: 10.1016/0092-8674(89)90685-5  0.621
1989 Klausner RD. Architectural editing: determining the fate of newly synthesized membrane proteins The New Biologist. 1: 3-8. PMID 2488271  0.346
1988 Rouault TA, Hentze MW, Caughman SW, Harford JB, Klausner RD. Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA. Science (New York, N.Y.). 241: 1207-10. PMID 3413484 DOI: 10.1126/Science.3413484  0.317
1988 Lippincott-Schwartz J, Bonifacino JS, Yuan LC, Klausner RD. Degradation from the endoplasmic reticulum: disposing of newly synthesized proteins. Cell. 54: 209-20. PMID 3292055 DOI: 10.1016/0092-8674(88)90553-3  0.661
1988 Baniyash M, Garcia-Morales P, Bonifacino JS, Samelson LE, Klausner RD. Disulfide linkage of the zeta and eta chains of the T cell receptor. Possible identification of two structural classes of receptors. The Journal of Biological Chemistry. 263: 9874-8. PMID 3290215  0.568
1988 Sussman JJ, Bonifacino JS, Lippincott-Schwartz J, Weissman AM, Saito T, Klausner RD, Ashwell JD. Failure to synthesize the T cell CD3-zeta chain: structure and function of a partial T cell receptor complex. Cell. 52: 85-95. PMID 3278811 DOI: 10.1016/0092-8674(88)90533-8  0.633
1988 Weissman AM, Baniyash M, Hou D, Samelson LE, Burgess WH, Klausner RD. Molecular cloning of the zeta chain of the T cell antigen receptor. Science (New York, N.Y.). 239: 1018-21. PMID 3278377 DOI: 10.1126/Science.3278377  0.339
1988 Bonifacino JS, Chen C, Lippincott-Schwartz J, Ashwell JD, Klausner RD. Subunit interactions within the T-cell antigen receptor: clues from the study of partial complexes. Proceedings of the National Academy of Sciences of the United States of America. 85: 6929-33. PMID 3261872 DOI: 10.1073/Pnas.85.18.6929  0.657
1988 Bonifacino JS, Lippincott-Schwartz J, Chen C, Antusch D, Samelson LE, Klausner RD. Association and dissociation of the murine T cell receptor associated protein (TRAP). Early events in the biosynthesis of a multisubunit receptor. The Journal of Biological Chemistry. 263: 8965-71. PMID 3259950  0.679
1988 Bonifacino JS, Mer?ep M, Sussman JJ, Klausner RD, Ashwell JD. The T-cell antigen receptor: a complex signal-transducing molecule. Princess Takamatsu Symposia. 19: 87-104. PMID 2978621  0.568
1988 Weissman AM, Hou D, Orloff DG, Modi WS, Seuanez H, O'Brien SJ, Klausner RD. Molecular cloning and chromosomal localization of the human T-cell receptor ζ chain: Distinction from the molecular CD3 complex Proceedings of the National Academy of Sciences of the United States of America. 85: 9709-9713. PMID 2974162 DOI: 10.1073/Pnas.85.24.9709  0.306
1988 Chen C, Bonifacino JS, Yuan LC, Klausner RD. Selective degradation of T cell antigen receptor chains retained in a pre-Golgi compartment. The Journal of Cell Biology. 107: 2149-61. PMID 2974039 DOI: 10.1083/Jcb.107.6.2149  0.559
1988 Willey RL, Bonifacino JS, Potts BJ, Martin MA, Klausner RD. Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160. Proceedings of the National Academy of Sciences of the United States of America. 85: 9580-4. PMID 2849111 DOI: 10.1073/Pnas.85.24.9580  0.429
1988 Mer?ep M, Bonifacino JS, Garcia-Morales P, Samelson LE, Klausner RD, Ashwell JD. T cell CD3-zeta eta heterodimer expression and coupling to phosphoinositide hydrolysis. Science (New York, N.Y.). 242: 571-4. PMID 2845582 DOI: 10.1126/Science.2845582  0.502
1987 Weissman AM, Samelson LE, Klausner RD. A new subunit of the human T-cell antigen receptor complex. Nature. 324: 480-2. PMID 3785426 DOI: 10.1038/324480a0  0.307
1987 Minami Y, Weissman AM, Samelson LE, Klausner RD. Building a multichain receptor: synthesis, degradation, and assembly of the T-cell antigen receptor. Proceedings of the National Academy of Sciences of the United States of America. 84: 2688-92. PMID 3495001 DOI: 10.1073/pnas.84.9.2688  0.367
1987 Samelson LE, Davidson WF, Morse HC, Klausner RD. Abnormal tyrosine phosphorylation on T-cell receptor in lymphoproliferative disorders. Nature. 324: 674-6. PMID 2432431 DOI: 10.1038/324674a0  0.307
1986 Samelson LE, Harford JB, Klausner RD. Identification of the components of the murine T cell antigen receptor complex. Cell. 43: 223-31. PMID 3878228 DOI: 10.1016/0092-8674(85)90027-3  0.332
1986 Bonifacino JS, Perez P, Klausner RD, Sandoval IV. Study of the transit of an integral membrane protein from secretory granules through the plasma membrane of secreting rat basophilic leukemia cells using a specific monoclonal antibody. The Journal of Cell Biology. 102: 516-22. PMID 3511074 DOI: 10.1083/Jcb.102.2.516  0.514
1985 Bonifacino JS, Klausner RD, Sandoval IV. A widely distributed nuclear protein immunologically related to the microtubule-associated protein MAP1 is associated with the mitotic spindle. Proceedings of the National Academy of Sciences of the United States of America. 82: 1146-50. PMID 3856252 DOI: 10.1073/Pnas.82.4.1146  0.471
1985 Rao KK, Shapiro D, Mattia E, Bridges K, Klausner R. Effects of alterations in cellular iron on biosynthesis of the transferrin receptor in K562 cells. Molecular and Cellular Biology. 5: 595-600. PMID 2985960 DOI: 10.1128/Mcb.5.4.595  0.344
1984 Sandoval IV, Bonifacino JS, Klausner RD, Henkart M, Wehland J. Role of microtubules in the organization and localization of the Golgi apparatus. The Journal of Cell Biology. 99: 113s-118s. PMID 6146626 DOI: 10.1083/Jcb.99.1.113S  0.495
1983 Wehland J, Henkart M, Klausner R, Sandoval IV. Role of microtubules in the distribution of the Golgi apparatus: effect of taxol and microinjected anti-alpha-tubulin antibodies. Proceedings of the National Academy of Sciences of the United States of America. 80: 4286-90. PMID 6136036 DOI: 10.1073/Pnas.80.14.4286  0.352
1982 Karnovsky MJ, Kleinfeld AM, Hoover RL, Klausner RD. The concept of lipid domains im membranes Journal of Cell Biology. 94: 1-6. PMID 6889603 DOI: 10.1083/Jcb.94.1.1  0.485
1982 Karnovsky MJ, Kleinfeld AM, Hoover RL, Dawidowicz EA, McIntyre DE, Salzman EA, Klausner RD. Lipid domains in membranes Annals of the New York Academy of Sciences. 401: 61-75. PMID 6762837 DOI: 10.1111/J.1749-6632.1982.Tb25707.X  0.445
1981 Hoover RL, Fujiwara K, Klausner RD, Bhalla DK, Tucker R, Karnovsky MJ. Effects of free fatty acids on the organization of cytoskeletal elements in lymphocytes. Molecular and Cellular Biology. 1: 939-48. PMID 7202114 DOI: 10.1128/MCB.1.10.939  0.473
1980 Klausner RD, Bhalla DK, Dragsten P, Hoover RL, Karnovsky MJ. Model for capping derived from inhibition of surface receptor capping by free fatty acids. Proceedings of the National Academy of Sciences of the United States of America. 77: 437-41. PMID 6928636 DOI: 10.1073/Pnas.77.1.437  0.47
1979 Klausner RD, Fishman MC, Karnovsky MJ. Ionophore A23187 disrupts membrane structure by modifying protein-lipid interactions Nature. 281: 82-83. PMID 121763 DOI: 10.1038/281082A0  0.488
Show low-probability matches.