Gary J. Gerfen - Publications

Affiliations: 
Yeshiva University, New York, NY, United States 
Area:
General Chemistry

51/92 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Carl AG, Harris LD, Feng M, Nordstrøm LU, Gerfen GJ, Evans GB, Silakov A, Almo SC, Grove TL. Narrow-Spectrum Antibiotic Targeting of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis. Biochemistry. PMID 32627538 DOI: 10.1021/Acs.Biochem.0C00070  0.309
2018 Nemeria NS, Gerfen G, Yang L, Zhang X, Jordan F. Evidence for functional and regulatory cross-talk between the tricarboxylic acid cycle 2-oxoglutarate dehydrogenase complex and 2-oxoadipate dehydrogenase on the l-lysine, l-hydroxylysine and l-tryptophan degradation pathways from studies in vitro. Biochimica Et Biophysica Acta. PMID 29752936 DOI: 10.1016/J.Bbabio.2018.05.001  0.305
2017 Nemeria NS, Gerfen G, Nareddy PR, Yang L, Zhang X, Szostak M, Jordan F. The mitochondrial 2-oxoadipate and 2-oxoglutarate dehydrogenase complexes share their E2 and E3 components for their function and both generate reactive oxygen species. Free Radical Biology & Medicine. 115: 136-145. PMID 29191460 DOI: 10.1016/J.Freeradbiomed.2017.11.018  0.314
2017 Nemeria NS, Gerfen G, Guevara E, Nareddy PR, Szostak M, Jordan F. The Human Krebs Cycle 2-Oxoglutarate Dehydrogenase Complex Creates an Additional Source of Superoxide/Hydrogen Peroxide from 2-Oxoadipate as Alternative Substrate. Free Radical Biology & Medicine. PMID 28435050 DOI: 10.1016/J.Freeradbiomed.2017.04.017  0.325
2014 Nemeria NS, Ambrus A, Patel H, Gerfen G, Adam-Vizi V, Tretter L, Zhou J, Wang J, Jordan F. Human 2-oxoglutarate dehydrogenase complex E1 component forms a thiamin-derived radical by aerobic oxidation of the enamine intermediate. The Journal of Biological Chemistry. 289: 29859-73. PMID 25210035 DOI: 10.1074/Jbc.M114.591073  0.35
2012 Yu MA, Egawa T, Shinzawa-Itoh K, Yoshikawa S, Guallar V, Yeh SR, Rousseau DL, Gerfen GJ. Two tyrosyl radicals stabilize high oxidation states in cytochrome C oxidase for efficient energy conservation and proton translocation. Journal of the American Chemical Society. 134: 4753-61. PMID 22296274 DOI: 10.1021/Ja210535W  0.375
2012 López-Garriga J, Román-Morales E, Ramos-Santana B, Gerfen G. P51 Activation of hydrogen sulfide by heme-superoxide limits triggering heme proteins oxidative products Nitric Oxide. 27: S35. DOI: 10.1016/J.Niox.2012.08.052  0.352
2011 Manzerova J, Krymov V, Gerfen GJ. Investigating the intermediates in the reaction of ribonucleoside triphosphate reductase from Lactobacillus leichmannii: An application of HF EPR-RFQ technology. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 213: 32-45. PMID 21944735 DOI: 10.1016/J.Jmr.2011.08.030  0.753
2011 Yu MA, Egawa T, Shinzawa-Itoh K, Yoshikawa S, Yeh SR, Rousseau DL, Gerfen GJ. Radical formation in cytochrome c oxidase. Biochimica Et Biophysica Acta. 1807: 1295-304. PMID 21718686 DOI: 10.1016/J.Bbabio.2011.06.012  0.366
2010 Sen KI, Wu H, Backer JM, Gerfen GJ. The structure of p85ni in class IA phosphoinositide 3-kinase exhibits interdomain disorder. Biochemistry. 49: 2159-66. PMID 20131869 DOI: 10.1021/Bi902171D  0.329
2010 Lohman GJ, Gerfen GJ, Stubbe J. Inactivation of Lactobacillus leichmannii ribonucleotide reductase by 2',2'-difluoro-2'-deoxycytidine 5'-triphosphate: adenosylcobalamin destruction and formation of a nucleotide-based radical. Biochemistry. 49: 1396-403. PMID 20088568 DOI: 10.1021/Bi9021318  0.315
2010 Yu MA, Egawa T, Yeh SR, Rousseau DL, Gerfen GJ. EPR characterization of ascorbyl and sulfur dioxide anion radicals trapped during the reaction of bovine Cytochrome c Oxidase with molecular oxygen. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 203: 213-9. PMID 20056464 DOI: 10.1016/J.Jmr.2009.12.017  0.324
2010 Moore RK, Guinto PJ, Wilson J, Gerfen G, Tardiff JC. Structural and Functional Characterization of the TNT1 Domain of Cardiac Troponin T Biophysical Journal. 98: 358a. DOI: 10.1016/J.Bpj.2009.12.1934  0.357
2009 Yeh HC, Gerfen GJ, Wang JS, Tsai AL, Wang LH. Characterization of the peroxidase mechanism upon reaction of prostacyclin synthase with peracetic acid. Identification of a tyrosyl radical intermediate. Biochemistry. 48: 917-28. PMID 19187034 DOI: 10.1021/Bi801382V  0.366
2009 Suarez J, Ranguelova K, Jarzecki AA, Manzerova J, Krymov V, Zhao X, Yu S, Metlitsky L, Gerfen GJ, Magliozzo RS. An oxyferrous heme/protein-based radical intermediate is catalytically competent in the catalase reaction of Mycobacterium tuberculosis catalase-peroxidase (KatG). The Journal of Biological Chemistry. 284: 7017-29. PMID 19139099 DOI: 10.1074/Jbc.M808106200  0.75
2009 Yu MA, Gerfen GJ, Yeh S, Rousseau DL. Rapid Freeze-quench Trapping Of Intermediates In The Reaction Of Cytochrome c Oxidase With Hydrogen Peroxide Biophysical Journal. 96: 565a. DOI: 10.1016/J.Bpj.2008.12.3708  0.323
2009 Moore RK, Wilson J, Guinto P, Riegelhaupt M, Gerfen G, Tardiff J. Structural and Functional Characterization of cTnT in Familial Hypertrophic Cardiomyopathy Biophysical Journal. 96: 499a. DOI: 10.1016/J.Bpj.2008.12.2576  0.302
2008 de Loubens G, Kent AD, Krymov V, Gerfen GJ, Beedle CC, Hendrickson DN. High frequency EPR on dilute solutions of the single molecule magnet Ni(4). Journal of Applied Physics. 103: 7B910-7B9103. PMID 19479002 DOI: 10.1063/1.2834447  0.369
2007 Ranguelova K, Girotto S, Gerfen GJ, Yu S, Suarez J, Metlitsky L, Magliozzo RS. Radical sites in Mycobacterium tuberculosis KatG identified using electron paramagnetic resonance spectroscopy, the three-dimensional crystal structure, and electron transfer couplings. The Journal of Biological Chemistry. 282: 6255-64. PMID 17204474 DOI: 10.1074/Jbc.M607309200  0.412
2005 Chattopadhyay M, Walter ED, Newell DJ, Jackson PJ, Aronoff-Spencer E, Peisach J, Gerfen GJ, Bennett B, Antholine WE, Millhauser GL. The octarepeat domain of the prion protein binds Cu(II) with three distinct coordination modes at pH 7.4. Journal of the American Chemical Society. 127: 12647-56. PMID 16144413 DOI: 10.1021/Ja053254Z  0.722
2005 Wilson JC, Wu G, Tsai AL, Gerfen GJ. Determination of the structural environment of the tyrosyl radical in prostaglandin H2 synthase-1: a high frequency ENDOR/EPR study. Journal of the American Chemical Society. 127: 1618-9. PMID 15700978 DOI: 10.1021/Ja043853Q  0.322
2004 Fu Z, Aronoff-Spencer E, Wu H, Gerfen GJ, Backer JM. The iSH2 domain of PI 3-kinase is a rigid tether for p110 and not a conformational switch. Archives of Biochemistry and Biophysics. 432: 244-51. PMID 15542063 DOI: 10.1016/J.Abb.2004.09.032  0.664
2003 Krymov V, Gerfen GJ. Analysis of the tuning and operation of reflection resonator EPR spectrometers. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 162: 466-78. PMID 12810032 DOI: 10.1016/S1090-7807(03)00109-5  0.324
2003 Burns CS, Aronoff-Spencer E, Legname G, Prusiner SB, Antholine WE, Gerfen GJ, Peisach J, Millhauser GL. Copper coordination in the full-length, recombinant prion protein. Biochemistry. 42: 6794-803. PMID 12779334 DOI: 10.1021/Bi027138+  0.732
2003 Fu Z, Aronoff-Spencer E, Backer JM, Gerfen GJ. The structure of the inter-SH2 domain of class IA phosphoinositide 3-kinase determined by site-directed spin labeling EPR and homology modeling. Proceedings of the National Academy of Sciences of the United States of America. 100: 3275-80. PMID 12629217 DOI: 10.1073/Pnas.0535975100  0.667
2002 Johansson MP, Sundholm D, Gerfen G, Wikström M. The spin distribution in low-spin iron porphyrins. Journal of the American Chemical Society. 124: 11771-80. PMID 12296745 DOI: 10.1021/Ja026523J  0.369
2002 Burns CS, Aronoff-Spencer E, Dunham CM, Lario P, Avdievich NI, Antholine WE, Olmstead MM, Vrielink A, Gerfen GJ, Peisach J, Scott WG, Millhauser GL. Molecular features of the copper binding sites in the octarepeat domain of the prion protein. Biochemistry. 41: 3991-4001. PMID 11900542 DOI: 10.1021/Bi011922X  0.727
2002 Avdievich NI, Gerfen GJ. Multifrequency probe for pulsed EPR and ENDOR spectroscopy. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 153: 178-85. PMID 11740892 DOI: 10.1006/Jmre.2001.2450  0.324
2001 Farrar CT, Hall DA, Gerfen GJ, Inati SJ, Griffin RG. Mechanism of dynamic nuclear polarization in high magnetic fields The Journal of Chemical Physics. 114: 4922-4933. DOI: 10.1063/1.1346640  0.384
2000 Aronoff-Spencer E, Burns CS, Avdievich NI, Gerfen GJ, Peisach J, Antholine WE, Ball HL, Cohen FE, Prusiner SB, Millhauser GL. Identification of the Cu2+ binding sites in the N-terminal domain of the prion protein by EPR and CD spectroscopy. Biochemistry. 39: 13760-71. PMID 11076515 DOI: 10.1021/Bi001472T  0.723
2000 Farrar CT, Hall DA, Gerfen GJ, Rosay M, Ardenkjaer-Larsen JH, Griffin RG. High-frequency dynamic nuclear polarization in the nuclear rotating frame. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 144: 134-41. PMID 10783283 DOI: 10.1006/Jmre.2000.2025  0.365
2000 Boulet AM, Walter ED, Schwartz DA, Gerfen GJ, Callis PR, Singel DJ. Electronic structure and hyperfine interactions in thioether-substituted tyrosyl radicals Chemical Physics Letters. 331: 108-114. DOI: 10.1016/S0009-2614(00)01154-4  0.61
1999 Bennati M, Gerfen GJ, Martinez GV, Griffin RG, Singel DJ, Millhauser GL. Nitroxide Side-Chain Dynamics in a Spin-Labeled Helix-Forming Peptide Revealed by High-Frequency (139.5-GHz) EPR Spectroscopy Journal of Magnetic Resonance. 139: 281-286. PMID 10423365 DOI: 10.1006/Jmre.1999.1769  0.645
1999 Bennati M, Farrar CT, Bryant JA, Inati SJ, Weis V, Gerfen GJ, Riggs-Gelasco P, Stubbe J, Griffin RG. Pulsed electron-nuclear double resonance (ENDOR) at 140 GHz. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 138: 232-43. PMID 10341127 DOI: 10.1006/Jmre.1999.1727  0.372
1999 Lawrence CC, Gerfen GJ, Samano V, Nitsche R, Robins MJ, Rétey J, Stubbe J. Binding of Cob(II)alamin to the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii. Identification of dimethylbenzimidazole as the axial ligand. The Journal of Biological Chemistry. 274: 7039-42. PMID 10066759 DOI: 10.1074/Jbc.274.11.7039  0.309
1997 Farrar CT, Gerfen GJ, Griffin RG, Force DA, Britt RD. Electronic Structure of the YDTyrosyl Radical in Photosystem II:  A High-Frequency Electron Paramagnetic Resonance Spectroscopic and Density Functional Theoretical Study The Journal of Physical Chemistry B. 101: 6634-6641. DOI: 10.1021/Jp9709518  0.411
1996 Halkides CJ, Bellew BF, Gerfen GJ, Farrar CT, Carter PH, Ruo B, Evans DA, Griffin RG, Singel DJ. High frequency (139.5 GHz) electron paramagnetic resonance spectroscopy of the GTP form of p21 ras with selective 17O labeling of threonine. Biochemistry. 35: 12194-2200. PMID 8810927 DOI: 10.1021/Bi9605954  0.591
1996 Bellew BF, Halkides CJ, Gerfen GJ, Griffin RG, Singel DJ. High frequency (139.5 GHz) electron paramagnetic resonance characterization of Mn(II)-H2(17)O interactions in GDP and GTP forms of p21 ras. Biochemistry. 35: 12186-93. PMID 8810926 DOI: 10.1021/Bi960594B  0.611
1996 Gerfen GJ, Bellew BF, Griffin RG, Singel DJ, Ekberg CA, Whittaker JW. High-Frequency Electron Paramagnetic Resonance Spectroscopy of the Apogalactose Oxidase Radical The Journal of Physical Chemistry. 100: 16739-16748. DOI: 10.1021/Jp960709L  0.644
1996 Gerfen GJ, Licht S, Willems JP, Hoffman BM, Stubbe J. Electron paramagnetic resonance investigations of a kinetically competent intermediate formed in ribonucleotide reduction: Evidence for a thiyl radical-cob(II)alamin interaction Journal of the American Chemical Society. 118: 8192-8197. DOI: 10.1021/Ja960363S  0.305
1995 Gerfen GJ, Becerra LR, Hall DA, Griffin RG, Temkin RJ, Singel DJ. High frequency (140 GHz) dynamic nuclear polarization: Polarization transfer to a solute in frozen aqueous solution The Journal of Chemical Physics. 102: 9494-9497. DOI: 10.1063/1.468818  0.622
1995 BECERRA LR, GERFEN GJ, BELLEW BF, BRYANT JA, HALL DA, INATI SJ, WEBER RT, UN S, PRISNER TF, MCDERMOTT AE, FISHBEIN KW, KREISCHER KE, TEMKIN RJ, SINGEL DJ, GRIFFIN RG. A Spectrometer for Dynamic Nuclear Polarization and Electron Paramagnetic Resonance at High Frequencies Journal of Magnetic Resonance, Series A. 117: 28-40. DOI: 10.1006/Jmra.1995.9975  0.643
1994 Gerfen GJ, Singel DJ. Determination of hyperfine interaction matrix principal values and principal axis orientations in an orientationally disordered solid: A multifrequency electron spin echo envelope modulation study of nitrogen‐15 in a copper(II)–15N–imidazole complex The Journal of Chemical Physics. 100: 4127-4137. DOI: 10.1063/1.466297  0.661
1993 Becerra LR, Gerfen GJ, Temkin RJ, Singel DJ, Griffin RG. Dynamic nuclear polarization with a cyclotron resonance maser at 5 T. Physical Review Letters. 71: 3561-3564. PMID 10055008 DOI: 10.1103/Physrevlett.71.3561  0.625
1993 Gerfen GJ, Bellew BF, Un S, Bollinger JM, Stubbe J, Griffin RG, Singel DJ. High-frequency (139.5 GHz) EPR spectroscopy of the tyrosyl radical in Escherichia coli ribonucleotide reductase Journal of the American Chemical Society. 115: 6420-6421. DOI: 10.1021/Ja00067A071  0.625
1992 Larsen RG, Gerfen GJ, Singel DJ. The glories of ESEEM: Measuring electron-nuclear dipolar couplings in orientationally disordered solids Applied Magnetic Resonance. 3: 369-381. DOI: 10.1007/Bf03166704  0.614
1991 Gerfen GJ, Hanna PM, Chasteen ND, Singel DJ. Characterization of the ligand environment of vanadyl complexes of apoferritin by multifrequency electron spin-echo envelope modulation Journal of the American Chemical Society. 113: 9513-9519. DOI: 10.1021/Ja00025A015  0.597
1991 Gerfen GJ, Bellew BF, Singel DJ. Line-narrowing in electron spin echo envelope modulation spectroscopy: a determination of the 15N hyperfine interaction parameters of para-nitrobenzo-15N-nitrile radical anion in frozen solution Chemical Physics Letters. 180: 490-496. DOI: 10.1016/0009-2614(91)85156-Q  0.625
1990 Gerfen GJ, Singel DJ. Determination of hyperfine interactions from the magnetic field dependence of nuclear modulation frequencies: An electron spin echo envelope modulation study of protons in γ‐irrradiated potassium dihydrogen arsenate The Journal of Chemical Physics. 93: 4571-4580. DOI: 10.1063/1.458697  0.645
1988 Flanagan HL, Gerfen GJ, Singel DJ. Multifrequency electron spin‐echo envelope modulation: The determination of nitro group14N hyperfine and quadrupole interactions of DPPH in frozen solution The Journal of Chemical Physics. 88: 20-24. DOI: 10.1063/1.454638  0.645
1988 Flanagan HL, Gerfen GJ, Lai A, Singel DJ. Orientation‐selective14N electron spin echo envelope modulation (ESEEM): The determination of14N quadrupole coupling tensor principal axis orientations in orientationally disordered solids The Journal of Chemical Physics. 88: 2162-2168. DOI: 10.1063/1.454049  0.631
Low-probability matches (unlikely to be authored by this person)
1998 Bothe H, Darley DJ, Albracht SP, Gerfen GJ, Golding BT, Buckel W. Identification of the 4-glutamyl radical as an intermediate in the carbon skeleton rearrangement catalyzed by coenzyme B12-dependent glutamate mutase from Clostridium cochlearium. Biochemistry. 37: 4105-13. PMID 9521732 DOI: 10.1021/Bi971393Q  0.298
2006 Mansoorabadi SO, Seravalli J, Furdui C, Krymov V, Gerfen GJ, Begley TP, Melnick J, Ragsdale SW, Reed GH. EPR spectroscopic and computational characterization of the hydroxyethylidene-thiamine pyrophosphate radical intermediate of pyruvate:ferredoxin oxidoreductase. Biochemistry. 45: 7122-31. PMID 16752902 DOI: 10.1021/Bi0602516  0.296
2015 Prados-Rosales R, Toriola S, Nakouzi A, Chatterjee S, Stark R, Gerfen G, Tumpowsky P, Dadachova E, Casadevall A. Structural Characterization of Melanin Pigments from Commercial Preparations of the Edible Mushroom Auricularia auricula. Journal of Agricultural and Food Chemistry. 63: 7326-32. PMID 26244793 DOI: 10.1021/Acs.Jafc.5B02713  0.296
2009 Wu H, Shekar SC, Flinn RJ, El-Sibai M, Jaiswal BS, Sen KI, Janakiraman V, Seshagiri S, Gerfen GJ, Girvin ME, Backer JM. Regulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110alpha and are disrupted in oncogenic p85 mutants. Proceedings of the National Academy of Sciences of the United States of America. 106: 20258-63. PMID 19915146 DOI: 10.1073/Pnas.0902369106  0.294
2013 Sabat J, Egawa T, Lu C, Stuehr DJ, Gerfen GJ, Rousseau DL, Yeh SR. Catalytic intermediates of inducible nitric-oxide synthase stabilized by the W188H mutation. The Journal of Biological Chemistry. 288: 6095-106. PMID 23269673 DOI: 10.1074/Jbc.M112.403238  0.286
2015 Roche CJ, Talwar A, Palmer AF, Cabrales P, Gerfen G, Friedman JM. Evaluating the capacity to generate and preserve nitric oxide bioactivity in highly purified earthworm erythrocruorin: a giant polymeric hemoglobin with potential blood substitute properties. The Journal of Biological Chemistry. 290: 99-117. PMID 25371199 DOI: 10.1074/Jbc.M114.583260  0.286
2018 DeColli AA, Nemeria NS, Majumdar A, Gerfen GJ, Jordan F, Freel Meyers CL. Oxidative decarboxylation of pyruvate by 1-deoxy-D-xyulose 5-phosphate synthase, a central metabolic enzyme in bacteria. The Journal of Biological Chemistry. PMID 29784878 DOI: 10.1074/Jbc.Ra118.001980  0.277
2017 Benoit MP, Diaz-Valencia DJ, Asenjo AB, Gerfen GJ, Sharp DJ, Sosa HJ. Exploring the Mechanism of Microtubule Depolymerization by the Kinesin 13 KLP10A and it's Phosphoregulation Biophysical Journal. 112: 428a. DOI: 10.1016/J.Bpj.2016.11.2287  0.277
2016 Chatterjee C, Benoit MP, DePaoli V, Diaz-Valencia JD, Asenjo AB, Gerfen GJ, Sharp DJ, Sosa H. Distinct Interaction Modes of the Kinesin-13 Motor Domain with the Microtubule. Biophysical Journal. 110: 1593-1604. PMID 27074684 DOI: 10.1016/J.Bpj.2016.02.029  0.274
2018 Jordan F, Nemeria NS, Gerfen G. Human 2-oxo acid dehydrogenase multienzyme complexes: experimental observation of the thiamin diphosphate-enamine radical species and its contribution to generation of superoxide and hydrogen peroxide in vitro Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1859: e11. DOI: 10.1016/J.Bbabio.2018.09.034  0.272
1997 Hall DA, Maus DC, Gerfen GJ, Inati SJ, Becerra LR, Dahlquist FW, Griffin RG. Polarization-enhanced NMR spectroscopy of biomolecules in frozen solution. Science (New York, N.Y.). 276: 930-2. PMID 9139651 DOI: 10.1126/Science.276.5314.930  0.269
2020 Zhang X, Nemeria NS, Leandro J, Houten S, Lazarus MB, Gerfen GJ, Ozohanics O, Ambrus A, Nagy B, Brukh R, Jordan F. Structure-function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with L-lysine metabolism disorder. The Journal of Biological Chemistry. PMID 32303640 DOI: 10.1074/Jbc.Ra120.012761  0.268
2019 Bashiri G, Grove TL, Hegde SS, Lagautriere T, Gerfen GJ, Almo SC, Squire CJ, Blanchard JS, Baker EN. The active site of the branched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster. The Journal of Biological Chemistry. PMID 31315931 DOI: 10.1074/Jbc.Ra119.009498  0.267
1996 Licht S, Gerfen GJ, Stubbe J. Thiyl radicals in ribonucleotide reductases. Science (New York, N.Y.). 271: 477-81. PMID 8560260 DOI: 10.1126/Science.271.5248.477  0.266
2003 Lin Y, Gerfen GJ, Rousseau DL, Yeh SR. Ultrafast microfluidic mixer and freeze-quenching device. Analytical Chemistry. 75: 5381-6. PMID 14710815 DOI: 10.1021/Ac0346205  0.265
2010 Li X, Telser J, Kunz RC, Hoffman BM, Gerfen G, Ragsdale SW. Observation of organometallic and radical intermediates formed during the reaction of methyl-coenzyme M reductase with bromoethanesulfonate. Biochemistry. 49: 6866-76. PMID 20597483 DOI: 10.1021/Bi100650M  0.265
2016 Benoit MP, Diaz JD, Asenjo AB, Gerfen GJ, Sharp DJ, Sosa HJ. Exploring the Mechanisms of a Phosphorylation Induced Inhibition of Microtubule Depolymerization in the Kinesin 13 KLP10A Biophysical Journal. 110: 462a. DOI: 10.1016/J.Bpj.2015.11.2471  0.256
2019 Jordan F, Nemeria N, Gerfen G. Human 2-Oxoglutarate Dehydrogenase and 2-Oxoadipate Dehydrogenase Both Generate Superoxide/HO in a Side Reaction and Each Could Contribute to Oxidative Stress in Mitochondria. Neurochemical Research. PMID 30847859 DOI: 10.1007/S11064-019-02765-W  0.25
2007 Eisenman HC, Mues M, Weber SE, Frases S, Chaskes S, Gerfen G, Casadevall A. Cryptococcus neoformans laccase catalyses melanin synthesis from both D- and L-DOPA. Microbiology (Reading, England). 153: 3954-62. PMID 18048910 DOI: 10.1099/Mic.0.2007/011049-0  0.245
2015 Giacco F, Du X, Carratú A, Gerfen GJ, D'Apolito M, Giardino I, Rasola A, Marin O, Divakaruni AS, Murphy AN, Shah MS, Brownlee M. GLP-1 Cleavage Product Reverses Persistent ROS Generation After Transient Hyperglycemia by Disrupting an ROS-Generating Feedback Loop. Diabetes. 64: 3273-84. PMID 26294429 DOI: 10.2337/Db15-0084  0.227
2002 Dorlet P, Seibold SA, Babcock GT, Gerfen GJ, Smith WL, Tsai AL, Un S. High-field EPR study of tyrosyl radicals in prostaglandin H(2) synthase-1. Biochemistry. 41: 6107-14. PMID 11994006 DOI: 10.1021/Bi015871F  0.227
2019 Meng F, Kaul D, Thangaswamy S, Bhutoria S, Gerfen G, Branch C, Intaglietta M, Acharya SA. Semisynthetic supra plasma expanders: a new class of therapeutics to improve microcircualtion in sickle cell anaemia. Artificial Cells, Nanomedicine, and Biotechnology. 47: 73-82. PMID 30663492 DOI: 10.1080/21691401.2018.1543194  0.225
2019 Almo SC, Grove TL, Bashiri G, Hegde ss, Lagautriere tl, Gerfen G, Squire CJ, Blanchard js, Baker EN. Dihydroxyacid dehydratase (IlvD) from Mycobacterium tuberculosis is an essential biosynthetic enzyme with an Fe2-S2 cluster at its active site Journal of Biological Chemistry. DOI: 10.2210/Pdb6Ovt/Pdb  0.224
2011 Tsai AL, Wu G, Rogge CE, Lü JM, Peng S, Van Der Donk WA, Palmer G, Gerfen GJ, Kulmacz RJ. Structural comparisons of arachidonic acid-induced radicals formed by prostaglandin H synthase-1 and -2 Journal of Inorganic Biochemistry. 105: 366-374. PMID 21421123 DOI: 10.1016/J.Jinorgbio.2010.11.012  0.223
2017 Almeida-Paes R, Almeida-Silva F, Pinto GCM, Almeida MA, Muniz MM, Pizzini CV, Gerfen GJ, Nosanchuk JD, Zancopé-Oliveira RM. L-tyrosine induces the production of a pyomelanin-like pigment by the parasitic yeast-form of Histoplasma capsulatum. Medical Mycology. PMID 28992332 DOI: 10.1093/Mmy/Myx068  0.219
2014 Friedman J, Roche C, Navati M, Gerfen G. Hemoglobin as a source of long-lived bioactive nitric oxide: Evaluating the nitrite anhydrase reaction Nitric Oxide. 42: 121. DOI: 10.1016/J.Niox.2014.09.068  0.217
2009 Schweitzer AD, Howell RC, Jiang Z, Bryan RA, Gerfen G, Chen CC, Mah D, Cahill S, Casadevall A, Dadachova E. Physico-chemical evaluation of rationally designed melanins as novel nature-inspired radioprotectors. Plos One. 4: e7229. PMID 19789711 DOI: 10.1371/Journal.Pone.0007229  0.214
1998 Gerfen GJ, van der Donk WA, Yu G, McCarthy JR, Jarvi ET, Matthews DP, Farrar C, Griffin RG, Stubbe J. Characterization of a Substrate-Derived Radical Detected during the Inactivation of Ribonucleotide Reductase fromEscherichia coliby 2‘-Fluoromethylene-2‘-deoxycytidine 5‘-Diphosphate Journal of the American Chemical Society. 120: 3823-3835. DOI: 10.1021/Ja972166E  0.214
2012 Revskaya E, Chu P, Howell RC, Schweitzer AD, Bryan RA, Harris M, Gerfen G, Jiang Z, Jandl T, Kim K, Ting LM, Sellers RS, Dadachova E, Casadevall A. Compton scattering by internal shields based on melanin-containing mushrooms provides protection of gastrointestinal tract from ionizing radiation. Cancer Biotherapy & Radiopharmaceuticals. 27: 570-6. PMID 23113595 DOI: 10.1089/Cbr.2012.1318  0.208
2008 Chaskes S, Frases S, Cammer M, Gerfen G, Casadevall A. Growth and pigment production on D-tryptophan medium by Cryptococcus gattii, Cryptococcus neoformans, and Candida albicans. Journal of Clinical Microbiology. 46: 255-64. PMID 17989195 DOI: 10.1128/Jcm.01721-07  0.208
2004 Seravalli J, Xiao Y, Gu W, Cramer SP, Antholine WE, Krymov V, Gerfen GJ, Ragsdale SW. Evidence that NiNi acetyl-CoA synthase is active and that the CuNi enzyme is not. Biochemistry. 43: 3944-55. PMID 15049702 DOI: 10.1021/Bi036194N  0.206
1998 van der Donk WA, Gerfen GJ, Stubbe J. Direct EPR Spectroscopic Evidence for an Allylic Radical Generated from (E)-2‘-Fluoromethylene-2‘-deoxycytidine 5‘-Diphosphate byE.coliRibonucleotide Reductase Journal of the American Chemical Society. 120: 4252-4253. DOI: 10.1021/Ja9740273  0.155
1985 Fraser GT, Nelson DD, Gerfen GJ, Klemperer W. The rotational spectrum, barrier to internal rotation, and structure of NH3-N2O The Journal of Chemical Physics. 83: 5442-5449. DOI: 10.1063/1.449714  0.151
1995 van der Donk WA, Stubbe J, Gerfen GJ, Bellew BF, Griffin RG. EPR Investigations of the Inactivation of E. coli Ribonucleotide Reductase with 2'-Azido-2'-deoxyuridine 5'-Diphosphate: Evidence for the Involvement of the Thiyl Radical of C225-R1 Journal of the American Chemical Society. 117: 8908-8916. DOI: 10.1021/Ja00140A003  0.105
2022 Smith DFQ, Mudrak NJ, Zamith-Miranda D, Honorato L, Nimrichter L, Chrissian C, Smith B, Gerfen G, Stark RE, Nosanchuk JD, Casadevall A. Melanization of Is Associated with Alteration of Extracellular pH. Journal of Fungi (Basel, Switzerland). 8. PMID 36294632 DOI: 10.3390/jof8101068  0.097
2012 Almeida-Paes R, Frases S, Araújo Gde S, de Oliveira MM, Gerfen GJ, Nosanchuk JD, Zancopé-Oliveira RM. Biosynthesis and functions of a melanoid pigment produced by species of the sporothrix complex in the presence of L-tyrosine. Applied and Environmental Microbiology. 78: 8623-30. PMID 23042177 DOI: 10.1128/Aem.02414-12  0.088
2015 Prados-Rosales R, Toriola S, Nakouzi A, Chatterjee S, Stark R, Gerfen G, Tumpowsky P, Dadachova E, Casadevall A. Structural characterization of melanin pigments from commercial preparations of the edible mushroom Auricularia auricula Journal of Agricultural and Food Chemistry. 63: 7326-7332. DOI: 10.1021/acs.jafc.5b02713  0.083
1984 Lee BH, Gerfen GJ, Miller MJ. Constituents of microbial iron chelators. Alternate syntheses of .delta.-N-hydroxy-L-ornithine derivatives and applications to the synthesis of rhodotorulic acid The Journal of Organic Chemistry. 49: 2418-2423. DOI: 10.1021/Jo00187A023  0.075
1984 LEE BH, GERFEN GJ, MILLER MJ. ChemInform Abstract: CONSTITUENTS OF MICROBIAL IRON CHELATORS. ALTERNATE SYNTHESES OF Δ-N-HYDROXY-L-ORNITHINE DERIVATIVES AND APPLICATIONS TO THE SYNTHESIS OF RHODOTORULIC ACID Chemischer Informationsdienst. 15. DOI: 10.1002/chin.198450254  0.063
2016 Briggs KJ, Koivunen P, Cao S, Backus KM, Olenchock BA, Patel H, Zhang Q, Signoretti S, Gerfen GJ, Richardson AL, Witkiewicz AK, Cravatt BF, Clardy J, Kaelin WG. Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine. Cell. 166: 126-139. PMID 27368101 DOI: 10.1016/J.Cell.2016.05.042  0.05
2021 Almeida-Paes R, Figueiredo-Carvalho MH, da Silva LB, Gerfen G, S Araújo GR, Frases S, Zancopé-Oliveira RM, Nosanchuk JD. produces a melanin-like pigment that protects against stress conditions encountered during parasitism. Future Microbiology. 16: 509-520. PMID 33960816 DOI: 10.2217/fmb-2020-0228  0.038
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