Roman Osman, PhD - Publications

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Biophysics

105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Li CW, Menconi F, Osman R, Mezei M, Jacobson EM, Concepcion E, David CS, Kastrinsky DB, Ohlmeyer M, Tomer Y. Identifying a small molecule blocking antigen presentation in autoimmune thyroiditis. The Journal of Biological Chemistry. PMID 26703475 DOI: 10.1074/jbc.M115.694687  0.76
2015 Osman R, Mezei M, Engel S. The role of protein "Stability patches" in molecular recognition: A case study of the human growth hormone-receptor complex. Journal of Computational Chemistry. PMID 26691434 DOI: 10.1002/jcc.24276  0.76
2015 Maillet EL, Cui M, Jiang P, Mezei M, Hecht E, Quijada J, Margolskee RF, Osman R, Max M. Characterization of the Binding Site of Aspartame in the Human Sweet Taste Receptor. Chemical Senses. 40: 577-86. PMID 26377607 DOI: 10.1093/chemse/bjv045  0.76
2014 Pasi M, Maddocks JH, Beveridge D, Bishop TC, Case DA, Cheatham T, Dans PD, Jayaram B, Lankas F, Laughton C, Mitchell J, Osman R, Orozco M, Pérez A, Petkevi?i?t? D, et al. μABC: a systematic microsecond molecular dynamics study of tetranucleotide sequence effects in B-DNA. Nucleic Acids Research. 42: 12272-83. PMID 25260586 DOI: 10.1093/nar/gku855  0.76
2014 Elmowafy E, Osman R, El-Shamy AHa, Awad GAs. Nanocomplexes of an insulinotropic drug: optimization, microparticle formation, and antidiabetic activity in rats International Journal of Nanomedicine. 9: 4449-4465. PMID 25258534 DOI: 10.2147/IJN.S66876  0.01
2014 Elmowafy E, Osman R, El-Shamy AEHA, Awad GA. Stable colloidal chitosan/alginate nanocomplexes: Fabrication, formulation optimization and repaglinide loading International Journal of Pharmacy and Pharmaceutical Sciences. 6: 520-525.  0.01
2013 Osman R, Saim N. Selective extraction of organic contaminants from soil using pressurised liquid extraction Journal of Chemistry. DOI: 10.1155/2013/357252  0.01
2013 Abdul Halim MI, Saim N, Osman R, Jasmani H, Abdul Aziz NS. Multivariate chemometric discrimination of blue gel-pen inks by fourier transform infrared spectroscopy: Diskriminasi kimometrik statistik terhadap pen gel dakwat biru dengan spektroskopi sinar merah Ieee Symposium On Computers and Informatics, Isci 2013. 236-240. DOI: 10.1109/ISCI.2013.6612410  0.01
2013 Abdul Halim MI, Saim N, Osman R, Jasmani H, Abidin NNZ. Discrimination of black ballpoint pen inks by high performance liquid chromatography (HPLC) | Diskriminasi pen mata bola berdakwat hitam menggunakan kromatografi cecair berprestasi tinggi Malaysian Journal of Analytical Sciences. 17: 230-235.  0.01
2012 Joseph TT, Osman R. Convergent transmission of RNAi guide-target mismatch information across Argonaute internal allosteric network. Plos Computational Biology. 8: e1002693. PMID 23028290 DOI: 10.1371/journal.pcbi.1002693  0.76
2012 Joseph TT, Osman R. Thermodynamic basis of selectivity in guide-target-mismatched RNA interference. Proteins. 80: 1283-98. PMID 22275138 DOI: 10.1002/prot.24025  0.76
2011 Gerona-Navarro G, Yoel-Rodríguez, Mujtaba S, Frasca A, Patel J, Zeng L, Plotnikov AN, Osman R, Zhou MM. Rational design of cyclic peptide modulators of the transcriptional coactivator CBP: a new class of p53 inhibitors. Journal of the American Chemical Society. 133: 2040-3. PMID 21271695 DOI: 10.1021/ja107761h  0.76
2010 Menconi F, Osman R, Monti MC, Greenberg DA, Concepcion ES, Tomer Y. Shared molecular amino acid signature in the HLA-DR peptide binding pocket predisposes to both autoimmune diabetes and thyroiditis. Proceedings of the National Academy of Sciences of the United States of America. 107: 16899-903. PMID 20837527 DOI: 10.1073/pnas.1009511107  0.76
2010 Lupyan D, Mezei M, Logothetis DE, Osman R. A molecular dynamics investigation of lipid bilayer perturbation by PIP2. Biophysical Journal. 98: 240-7. PMID 20338845 DOI: 10.1016/j.bpj.2009.09.063  0.76
2010 Menconi F, Huber A, Osman R, Concepcion E, Jacobson EM, Stefan M, David CS, Tomer Y. Tg.2098 is a major human thyroglobulin T-cell epitope. Journal of Autoimmunity. 35: 45-51. PMID 20303712 DOI: 10.1016/j.jaut.2010.01.004  0.76
2010 Lavery R, Zakrzewska K, Beveridge D, Bishop TC, Case DA, Cheatham T, Dixit S, Jayaram B, Lankas F, Laughton C, Maddocks JH, Michon A, Osman R, Orozco M, Perez A, et al. A systematic molecular dynamics study of nearest-neighbor effects on base pair and base pair step conformations and fluctuations in B-DNA. Nucleic Acids Research. 38: 299-313. PMID 19850719 DOI: 10.1093/nar/gkp834  0.76
2010 Eichenbaum KD, Rodríguez Y, Mezei M, Osman R. The energetics of the acetylation switch in p53-mediated transcriptional activation. Proteins. 78: 447-56. PMID 19731376 DOI: 10.1002/prot.22565  0.76
2009 Jacobson EM, Yang H, Menconi F, Wang R, Osman R, Skrabanek L, Li CW, Fadlalla M, Gandhi A, Chaturvedi V, Smith EP, Schwemberger S, Osterburg A, Babcock GF, Tomer Y. Employing a recombinant HLA-DR3 expression system to dissect major histocompatibility complex II-thyroglobulin peptide dynamism: a genetic, biochemical, and reverse immunological perspective. The Journal of Biological Chemistry. 284: 34231-43. PMID 19776016 DOI: 10.1074/jbc.M109.041574  0.76
2008 Rodríguez Y, Mezei M, Osman R. The PT1-Ca2+ Gla domain binds to a membrane through two dipalmitoylphosphatidylserines. A computational study. Biochemistry. 47: 13267-78. PMID 19086158 DOI: 10.1021/bi801199v  0.76
2008 Cui M, Mezei M, Osman R. Prediction of protein loop structures using a local move Monte Carlo approach and a grid-based force field. Protein Engineering, Design & Selection : Peds. 21: 729-35. PMID 18957407 DOI: 10.1093/protein/gzn056  0.76
2008 Menconi F, Monti MC, Greenberg DA, Oashi T, Osman R, Davies TF, Ban Y, Jacobson EM, Concepcion ES, Li CW, Tomer Y. Molecular amino acid signatures in the MHC class II peptide-binding pocket predispose to autoimmune thyroiditis in humans and in mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 14034-9. PMID 18779568 DOI: 10.1073/pnas.0806584105  0.76
2008 Yamoah K, Oashi T, Sarikas A, Gazdoiu S, Osman R, Pan ZQ. Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail. Proceedings of the National Academy of Sciences of the United States of America. 105: 12230-5. PMID 18723677 DOI: 10.1073/pnas.0806155105  0.76
2008 Cui M, Mezei M, Osman R. Modeling dimerizations of transmembrane proteins using Brownian dynamics simulations. Journal of Computer-Aided Molecular Design. 22: 553-61. PMID 18338226 DOI: 10.1007/s10822-008-9198-3  0.76
2008 Cui M, Jiang P, Maillet E, Max M, Margolskee RF, Osman R. Molecular models of sweet taste receptors provide insights into function Acs Symposium Series. 979: 117-132. DOI: 10.1021/bk-2008-0979.ch008  0.76
2008 Jiang P, Maillet E, Cui M, Osman R, Max M, Margolskee RF. Making sense of the sweet taste receptor Acs Symposium Series. 979: 48-64. DOI: 10.1021/bk-2008-0979.ch003  0.76
2007 Kentsis A, Gindin T, Mezei M, Osman R. Calculation of the free energy and cooperativity of protein folding Plos One. 2. PMID 17505540 DOI: 10.1371/journal.pone.0000446  0.76
2007 Rodríguez Y, Mezei M, Osman R. Association free energy of dipalmitoylphosphatidylserines in a mixed dipalmitoylphosphatidylcholine membrane. Biophysical Journal. 92: 3071-80. PMID 17277191 DOI: 10.1529/biophysj.106.089078  0.76
2006 Cui M, Jiang P, Maillet E, Max M, Margolskee RF, Osman R. The heterodimeric sweet taste receptor has multiple potential ligand binding sites. Current Pharmaceutical Design. 12: 4591-600. PMID 17168764 DOI: 10.2174/138161206779010350  0.76
2005 Kentsis A, Mezei M, Osman R. Origin of the sequence-dependent polyproline II structure in unfolded peptides Proteins: Structure, Function and Genetics. 61: 769-776. PMID 16193481 DOI: 10.1002/prot.20655  0.76
2005 Dixit SB, Beveridge DL, Case DA, Cheatham TE, Giudice E, Lankas F, Lavery R, Maddocks JH, Osman R, Sklenar H, Thayer KM, Varnai P. Molecular dynamics simulations of the 136 unique tetranucleotide sequences of DNA oligonucleotides. II: sequence context effects on the dynamical structures of the 10 unique dinucleotide steps. Biophysical Journal. 89: 3721-40. PMID 16169978 DOI: 10.1529/biophysj.105.067397  0.76
2005 Jiang P, Cui M, Zhao B, Snyder LA, Benard LM, Osman R, Max M, Margolskee RF. Identification of the cyclamate interaction site within the transmembrane domain of the human sweet taste receptor subunit T1R3. The Journal of Biological Chemistry. 280: 34296-305. PMID 16076846 DOI: 10.1074/jbc.M505255200  0.76
2005 Fuxreiter M, Mezei M, Simon I, Osman R. Interfacial water as a "hydration fingerprint" in the noncognate complex of BamHI. Biophysical Journal. 89: 903-11. PMID 15894630 DOI: 10.1529/biophysj.105.063263  0.76
2005 Jiang P, Cui M, Ji Q, Snyder L, Liu Z, Benard L, Margolskee RF, Osman R, Max M. Molecular mechanisms of sweet receptor function. Chemical Senses. 30: i17-8. PMID 15738096 DOI: 10.1093/chemse/bjh091  0.76
2005 Huang W, Osman R, Gershengorn MC. Agonist-induced conformational changes in thyrotropin-releasing hormone receptor type I: disulfide cross-linking and molecular modeling approaches. Biochemistry. 44: 2419-31. PMID 15709754 DOI: 10.1021/bi048808+  0.76
2005 Jiang P, Cui M, Zhao B, Liu Z, Snyder LA, Benard LM, Osman R, Margolskee RF, Max M. Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste. The Journal of Biological Chemistry. 280: 15238-46. PMID 15668251 DOI: 10.1074/jbc.M414287200  0.76
2005 Miller F, Kentsis A, Osman R, Pan ZQ. Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL·hypoxia-inducible transcription factor-1α complex Journal of Biological Chemistry. 280: 7985-7996. PMID 15611064 DOI: 10.1074/jbc.M413160200  0.76
2004 Osman R. Modeling the TSH Receptor. Thyroid : Official Journal of the American Thyroid Association. 14: 989-90. PMID 15650351 DOI: 10.1089/thy.2004.14.989  0.76
2004 Beveridge DL, Barreiro G, Byun KS, Case DA, Cheatham TE, Dixit SB, Giudice E, Lankas F, Lavery R, Maddocks JH, Osman R, Seibert E, Sklenar H, Stoll G, Thayer KM, et al. Molecular dynamics simulations of the 136 unique tetranucleotide sequences of DNA oligonucleotides. I. Research design and results on d(CpG) steps. Biophysical Journal. 87: 3799-813. PMID 15326025 DOI: 10.1529/biophysj.104.045252  0.76
2004 Lu X, Huang W, Worthington S, Drabik P, Osman R, Gershengorn MC. A model of inverse agonist action at thyrotropin-releasing hormone receptor type 1: role of a conserved tryptophan in helix 6. Molecular Pharmacology. 66: 1192-200. PMID 15306657 DOI: 10.1124/mol.104.000349  0.76
2004 Kentsis A, Mezei M, Gindin T, Osman R. Unfolded State of Polyalanine Is a Segmented Polyproline II Helix Proteins: Structure, Function and Genetics. 55: 493-501. PMID 15103613 DOI: 10.1002/prot.20051  0.76
2004 Ban Y, Davies TF, Greenberg DA, Concepcion ES, Osman R, Oashi T, Tomer Y. Arginine at position 74 of the HLA-DR beta1 chain is associated with Graves' disease. Genes and Immunity. 5: 203-8. PMID 15029234 DOI: 10.1038/sj.gene.6364059  0.76
2003 Seibert E, Ross JB, Osman R. Contribution of opening and bending dynamics to specific recognition of DNA damage. Journal of Molecular Biology. 330: 687-703. PMID 12850140  0.76
2003 Kentsis A, Mezei M, Osman R. MC-PHS: A Monte Carlo implementation of the primary hydration shell for protein folding and design Biophysical Journal. 84: 805-815. PMID 12547765  0.76
2003 Seibert E, Chin AS, Pfleiderer W, Hawkins ME, Laws WR, Osman R, Ross JBA. pH-dependent spectroscopy and electronic structure of the guanine analogue 6,8-dimethylisoxanthopterin Journal of Physical Chemistry A. 107: 178-185. DOI: 10.1021/jp026904j  0.76
2003 Fuxreiter M, Osman R, Simon I. Computational approaches to restriction endonucleases Journal of Molecular Structure: Theochem. 666: 469-479. DOI: 10.1016/j.theochem.2003.08.071  0.76
2002 Fuxreiter M, Luo N, Jedlovszky P, Simon I, Osman R. Role of base flipping in specific recognition of damaged DNA by repair enzymes. Journal of Molecular Biology. 323: 823-34. PMID 12417196 DOI: 10.1016/S0022-2836(02)00999-3  0.76
2002 Seibert E, Ross JB, Osman R. Role of DNA flexibility in sequence-dependent activity of uracil DNA glycosylase. Biochemistry. 41: 10976-84. PMID 12206669 DOI: 10.1021/bi026121o  0.76
2002 Yamaguchi H, Siebers JG, Furukawa A, Otagiri N, Osman R. Molecular dynamics simulation of a DNA containing a single strand break. Radiation Protection Dosimetry. 99: 103-8. PMID 12194259  0.76
2002 Seibert E, Ross JBA, Osman R. Quantum mechanical investigation of the electronic structure and spectral properties of 6,8-dimethylisoxanthopterin International Journal of Quantum Chemistry. 88: 28-33. DOI: 10.1002/qua.10075  0.76
2001 Rachofsky EL, Ross JB, Osman R. Conformation and dynamics of normal and damaged DNA. Combinatorial Chemistry & High Throughput Screening. 4: 675-706. PMID 11812262  0.76
2001 Fuxreiter M, Osman R. Probing the general base catalysis in the first step of BamHI action by computer simulations. Biochemistry. 40: 15017-23. PMID 11732923 DOI: 10.1021/bi010987x  0.76
2001 Rachofsky EL, Seibert E, Stivers JT, Osman R, Ross JB. Conformation and dynamics of abasic sites in DNA investigated by time-resolved fluorescence of 2-aminopurine. Biochemistry. 40: 957-67. PMID 11170417 DOI: 10.1021/bi001665g  0.76
2001 Rachofsky EL, Osman R, Ross JB. Probing structure and dynamics of DNA with 2-aminopurine: effects of local environment on fluorescence. Biochemistry. 40: 946-56. PMID 11170416 DOI: 10.1021/bi001664o  0.76
2001 Gershengorn MC, Osman R. Minireview: Insights into G protein-coupled receptor function using molecular models. Endocrinology. 142: 2-10. PMID 11145559 DOI: 10.1210/endo.142.1.7919  0.76
2001 Ho HH, Ganeshalingam N, Rosenhouse-Dantsker A, Osman R, Gershengorn MC. Charged residues at the intracellular boundary of transmembrane helices 2 and 3 independently affect constitutive activity of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor. The Journal of Biological Chemistry. 276: 1376-82. PMID 11031271 DOI: 10.1074/jbc.M007885200  0.76
2001 Rachofsky EL, Ross JBA, Krauss M, Osman R. CASSCF investigation of electronic excited states of 2-aminopurine Journal of Physical Chemistry A. 105: 190-197.  0.76
2000 Rosenhouse-Dantsker A, Osman R. Application of the primary hydration shell approach to locally enhanced sampling simulated annealing: computer simulation of thyrotropin-releasing hormone in water. Biophysical Journal. 79: 66-79. PMID 10866938 DOI: 10.1016/S0006-3495(00)76274-6  0.76
2000 Osman R, Fuxreiter M, Luo N. Specificity of damage recognition and catalysis of DNA repair. Computers & Chemistry. 24: 331-9. PMID 10816003  0.76
1999 Fuxreiter M, Warshel A, Osman R. Role of active site residues in the glycosylase step of T4 endonuclease V. Computer simulation studies on ionization states. Biochemistry. 38: 9577-89. PMID 10423235 DOI: 10.1021/bi9901937  0.76
1999 Luo N, Mehler E, Osman R. Specificity and catalysis of uracil DNA glycosylase. A molecular dynamics study of reactant and product complexes with DNA. Biochemistry. 38: 9209-20. PMID 10413495 DOI: 10.1021/bi990262h  0.76
1999 Krauss M, Luo N, Nirmala R, Osman R. Molecular dynamics and quantum chemical study of endonuclease v catalytic mechanism Acs Symposium Series. 721: 424-438.  0.76
1999 Luo N, Litvin A, Osman R. Theoretical Studies of Ribose and Its Radicals Produced by Hydrogen Abstraction from Ring Carbons Journal of Physical Chemistry A. 103: 592-600.  0.76
1998 Colson AO, Perlman JH, Jinsi-Parimoo A, Nussenzveig DR, Osman R, Gershengorn MC. A hydrophobic cluster between transmembrane helices 5 and 6 constrains the thyrotropin-releasing hormone receptor in an inactive conformation. Molecular Pharmacology. 54: 968-78. PMID 9855624  0.76
1998 Yamaguchi H, van Aalten DM, Pinak M, Furukawa A, Osman R. Essential dynamics of DNA containing a cis.syn cyclobutane thymine dimer lesion. Nucleic Acids Research. 26: 1939-46. PMID 9518486 DOI: 10.1093/nar/26.8.1939  0.76
1998 Colson AO, Perlman JH, Smolyar A, Gershengorn MC, Osman R. Static and dynamic roles of extracellular loops in G-protein-coupled receptors: a mechanism for sequential binding of thyrotropin-releasing hormone to its receptor. Biophysical Journal. 74: 1087-100. PMID 9512011 DOI: 10.1016/S0006-3495(98)77827-0  0.76
1998 Miller J, Cooney M, Miaskiewicz K, Osman R. Modeling Duplex DNA Oligonucleotides with Modified Pyrimidine Bases Acs Symposium Series. 682: 312-328.  0.76
1998 Rachofsky EL, Ross JBA, Krauss M, Osman R. Spectroscopy of 2-aminopurine: An MCSCF study Acta Physica Polonica A. 94: 735-748.  0.76
1997 Perlman JH, Colson AO, Jain R, Czyzewski B, Cohen LA, Osman R, Gershengorn MC. Role of the extracellular loops of the thyrotropin-releasing hormone receptor: evidence for an initial interaction with thyrotropin-releasing hormone. Biochemistry. 36: 15670-6. PMID 9398295 DOI: 10.1021/bi9713310  0.76
1997 Perlman JH, Colson AO, Wang W, Bence K, Osman R, Gershengorn MC. Interactions between conserved residues in transmembrane helices 1, 2, and 7 of the thyrotropin-releasing hormone receptor. The Journal of Biological Chemistry. 272: 11937-42. PMID 9115256 DOI: 10.1074/jbc.272.18.11937  0.76
1997 Fahr A, Laufer AH, Krauss M, Osman R. Gas phase absorption spectrum and cross sections of vinylperoxy (C2H3O2) radical Journal of Physical Chemistry A. 101: 4879-4886.  0.76
1997 Krauss M, Osman R. Electronic spectra of the H and OH adducts of cytosine Journal of Physical Chemistry A. 101: 4117-4120.  0.76
1997 Soirat AJA, Wong CF, Osman R, Weinstein H. Brownian dynamics simulations of the reactions of hydrated electrons with components of DNAs and a DNA double-helix Journal of Computational Chemistry. 18: 888-901.  0.76
1997 Luo N, Kombo DC, Osman R. Theoretical studies of hydrogen abstraction from 2-propanol by OH radical Journal of Physical Chemistry A. 101: 926-936.  0.76
1996 Pinak M, Yamaguchi H, Osman R. Molecular dynamics (MD) simulation of DNA dodecamer with 5-hydroxy-6-cytosinyl radical. Journal of Radiation Research. 37: 20-8. PMID 8699393  0.76
1996 Laakkonen LJ, Guarnieri F, Perlman JH, Gershengorn MC, Osman R. A refined model of the thyrotropin-releasing hormone (TRH) receptor binding pocket. Novel mixed mode Monte Carlo/stochastic dynamics simulations of the complex between TRH and TRH receptor. Biochemistry. 35: 7651-63. PMID 8672466 DOI: 10.1021/bi952203j  0.76
1996 Perlman JH, Laakkonen LJ, Guarnieri F, Osman R, Gershengorn MC. A refined model of the thyrotropin-releasing hormone (TRH) receptor binding pocket. Experimental analysis and energy minimization of the complex between TRH and TRH receptor. Biochemistry. 35: 7643-50. PMID 8672465 DOI: 10.1021/bi952202r  0.76
1996 Laakkonen L, Li W, Perlman JH, Guarnieri F, Osman R, Moeller KD, Gershengorn MC. Restricted analogues provide evidence of a biologically active conformation of thyrotropin-releasing hormone. Molecular Pharmacology. 49: 1092-6. PMID 8649348  0.76
1996 Gershengorn MC, Osman R. Molecular and cellular biology of thyrotropin-releasing hormone receptors. Physiological Reviews. 76: 175-91. PMID 8592728  0.76
1996 Miaskiewicz K, Miller J, Cooney M, Osman R. Computational simulations of DNA distortions by a cis,syn-cyclobutane thymine dimer lesion Journal of the American Chemical Society. 118: 9156-9163. DOI: 10.1021/ja9611304  0.76
1995 Perlman JH, Laakkonen L, Osman R, Gershengorn MC. Distinct roles for arginines in transmembrane helices 6 and 7 of the thyrotropin-releasing hormone receptor. Molecular Pharmacology. 47: 480-4. PMID 7700246  0.76
1995 Miaskiewicz K, Miller J, Ornstein R, Osman R. Molecular dynamics simulations of the effects of ring-saturated thymine lesions on DNA structure. Biopolymers. 35: 113-24. PMID 7696552 DOI: 10.1002/bip.360350112  0.76
1995 Krauss M, Osman R. Electronic spectra of H and OH adducts to benzene Chemical Physics Letters. 239: 258-262. DOI: 10.1016/0009-2614(95)00463-E  0.76
1995 Krauss M, Osman R. Absorption spectra of ethynyl, ethenyl, and phenyl peroxyl radicals Journal of Physical Chemistry. 99: 11387-11391.  0.76
1994 Perlman JH, Thaw CN, Laakkonen L, Bowers CY, Osman R, Gershengorn MC. Hydrogen bonding interaction of thyrotropin-releasing hormone (TRH) with transmembrane tyrosine 106 of the TRH receptor. The Journal of Biological Chemistry. 269: 1610-3. PMID 8294406  0.76
1994 Miller J, Miaskiewicz K, Osman R. Structure-function studies of DNA damage using ab initio quantum mechanics and molecular dynamics simulation. Annals of the New York Academy of Sciences. 726: 71-91. PMID 8092709  0.76
1994 Perlman JH, Laakkonen L, Osman R, Gershengorn MC. A model of the thyrotropin-releasing hormone (TRH) receptor binding pocket. Evidence for a second direct interaction between transmembrane helix 3 and TRH. The Journal of Biological Chemistry. 269: 23383-6. PMID 8089099  0.76
1994 Shafferman A, Ordentlich A, Barak D, Kronman C, Ber R, Bino T, Ariel N, Osman R, Velan B. Electrostatic attraction by surface charge does not contribute to the catalytic efficiency of acetylcholinesterase. The Embo Journal. 13: 3448-55. PMID 8062821  0.76
1994 Miaskiewicz K, Miller J, Osman R. Energetic basis for structural preferences in 5/6-hydroxy-5,6-dihydropyrimidines: products of ionizing and ultraviolet radiation action on DNA bases. Biochimica Et Biophysica Acta. 1218: 283-91. PMID 8049253 DOI: 10.1016/0167-4781(94)90179-1  0.76
1994 Miaskiewicz K, Osman R. Theoretical study on the deoxyribose radicals formed by hydrogen abstraction Journal of the American Chemical Society. 116: 232-238.  0.76
1994 Miaskiewicz K, Osman R. Molecular dynamics simulation of DNA with a primary radiation damage Radiation Protection Dosimetry. 52: 149-153.  0.76
1993 Smolyar A, Osman R. Role of threonine 342 in helix 7 of the 5-hydroxytryptamine type 1D receptor in ligand binding: an indirect mechanism for receptor selectivity. Molecular Pharmacology. 44: 882-5. PMID 8232238  0.76
1993 Miaskiewicz K, Miller J, Osman R. Ab initio theoretical study of the structures of thymine glycol and dihydrothymine. International Journal of Radiation Biology. 63: 677-86. PMID 8100254 DOI: 10.1080/09553009314552071  0.76
1993 Perlman JH, Laakkonen L, Thaw CN, Osman R, Gershengorn MC. Analysis of the role of transmembrane helix three of the thyrotropin-releasing hormone (TRH) receptor in directly binding TRH. Transactions of the Association of American Physicians. 106: 162-7. PMID 8036739  0.76
1993 Krauss M, Osman R. Electronic spectra of the neutral radical and H and OH adducts of uracil Journal of Physical Chemistry. 97: 13515-13518.  0.76
1993 Miaskiewicz K, Osman R, Weinstein H. Molecular dynamics simulation of the hydrated d(CGCGAATTCGCG)2 dodecamer Journal of the American Chemical Society. 115: 1526-1537.  0.76
1993 Pardo L, Osman R, Weinstein H, Rabinowitz JR. Mechanisms of nucleophilic addition to activated double bonds: 1,2- and 1,4-Michael addition of ammonia Journal of the American Chemical Society. 115: 8263-8269.  0.76
1992 Perlman JH, Nussenzveig DR, Osman R, Gershengorn MC. Thyrotropin-releasing hormone binding to the mouse pituitary receptor does not involve ionic interactions. A model for neutral peptide binding to G protein-coupled receptors. The Journal of Biological Chemistry. 267: 24413-7. PMID 1332958  0.76
1992 Pardo L, Ballesteros JA, Osman R, Weinstein H. On the use of the transmembrane domain of bacteriorhodopsin as a template for modeling the three-dimensional structure of guanine nucleotide-binding regulatory protein-coupled receptors. Proceedings of the National Academy of Sciences of the United States of America. 89: 4009-12. PMID 1315046  0.76
1992 Pardo L, Banfelder JR, Osman R. Theoretical studies of the kinetics, thermochemistry, and mechanism of H-abstraction from methanol and ethanol Journal of the American Chemical Society. 114: 2382-2390.  0.76
1991 Osman R, Pardo L, Banfelder J, Mazurek AP, Shvartzman L, Strauss R, Weinstein H. Molecular mechanisms of radiation induced DNA damage: H-addition to bases, direct ionization and double strand break Free Radical Research Communications. 12: 465-467. PMID 2060823 DOI: 10.3109/10715769109145819  0.76
1991 Ben-Harari RR, Dalton BA, Osman R, Maayani S. Kinetic characterization of 5-hydroxytryptamine receptor desensitization in isolated guinea-pig trachea and rabbit aorta Journal of Pharmacology and Experimental Therapeutics. 257: 416-424. PMID 1850475  0.76
1991 Osman R, Weinstein H. A mechanistic basis for design of selective agonists for 5-HT receptors Nida Research Monograph Series. 21-42. PMID 1753999  0.76
1991 Osman R, Miaskiewicz K, Weinstein H. Structure-function relations in radiation damaged DNA Basic Life Sciences. 58: 423-447; discussion . PMID 1667352  0.76
1991 Pardo L, Osman R, Banfelder J, Mazurek AP, Weinstein H. Molecular mechanisms of radiation induced DNA damage: H-abstraction and beta-cleavage Free Radical Research Communications. 12: 461-463. PMID 1648009  0.76
1991 Pardo L, Osman R, Banfelder J, Mazurek AP, Weinstein H. Molecular mechanisms of radiation induced DNA damage: H-abstraction and βcleavage Free Radical Research. 13: 461-463. DOI: 10.3109/10715769109145818  0.76
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