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James P. Scott-Browne, Ph.D. - Publications

Affiliations: 
2009 University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Immunology
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43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2025 DeGolier KR, Danis E, D'Antonio M, Cimons J, Yarnell M, Kedl RM, Kohler ME, Scott-Browne JP, Fry TJ. Antigen experience history directs distinct functional states of CD8 CAR T cells during the antileukemia response. Nature Immunology. 26: 68-81. PMID 39747430 DOI: 10.1038/s41590-024-02034-1  0.478
2024 Brown AJ, White J, Shaw L, Gross J, Slabodkin A, Kushner E, Greiff V, Matsuda J, Gapin L, Scott-Browne J, Kappler J, Marrack P. MHC heterozygosity limits T cell receptor variability in CD4 T cells. Science Immunology. 9: eado5295. PMID 38996008 DOI: 10.1126/sciimmunol.ado5295  0.66
2023 Fry T, DeGolier K, Danis E, D'Antonio M, Cimons J, Yarnell M, Kedl R, Kohler M, Scott-Browne J. Antigen experience history directs distinct functional states of CD8+ CAR T cells during the anti-leukemia response. Research Square. PMID 38196657 DOI: 10.21203/rs.3.rs-3712137/v1  0.472
2023 Bao K, Isik Can U, Miller MM, Brown IK, Dell'Aringa M, Dooms H, Seibold MA, Scott-Browne J, Lee Reinhardt R. A bifurcated role for c-Maf in Th2 and Tfh2 cells during helminth infection. Mucosal Immunology. PMID 37088263 DOI: 10.1016/j.mucimm.2023.04.002  0.333
2021 Brown IK, Dyjack N, Miller MM, Krovi H, Rios C, Woolaver R, Harmacek L, Tu TH, O'Connor BP, Danhorn T, Vestal B, Gapin L, Pinilla C, Seibold MA, Scott-Browne J, et al. Single cell analysis of host response to helminth infection reveals the clonal breadth, heterogeneity, and tissue-specific programming of the responding CD4+ T cell repertoire. Plos Pathogens. 17: e1009602. PMID 34106992 DOI: 10.1371/journal.ppat.1009602  0.369
2021 Liikanen I, Lauhan C, Quon S, Omilusik K, Phan AT, Bartrolí LB, Ferry A, Goulding J, Chen J, Scott-Browne JP, Yustein JT, Scharping NE, Witherden DA, Goldrath AW. Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells. The Journal of Clinical Investigation. 131. PMID 33792560 DOI: 10.1172/JCI143729  0.344
2021 Murray MP, Engel I, Seumois G, Herrera-De la Mata S, Rosales SL, Sethi A, Logandha Ramamoorthy Premlal A, Seo GY, Greenbaum J, Vijayanand P, Scott-Browne JP, Kronenberg M. Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure. Nature Communications. 12: 1446. PMID 33664261 DOI: 10.1038/s41467-021-21574-w  0.402
2020 Harsha Krovi S, Zhang J, Michaels-Foster MJ, Brunetti T, Loh L, Scott-Browne J, Gapin L. Thymic iNKT single cell analyses unmask the common developmental program of mouse innate T cells. Nature Communications. 11: 6238. PMID 33288744 DOI: 10.1038/s41467-020-20073-8  0.445
2019 Chen J, López-Moyado IF, Seo H, Lio CJ, Hempleman LJ, Sekiya T, Yoshimura A, Scott-Browne JP, Rao A. NR4A transcription factors limit CAR T cell function in solid tumours. Nature. PMID 30814732 DOI: 10.1038/S41586-019-0985-X  0.54
2019 Chen J, Scott-Browne JP, Lopez-Moyado IF, Hempleman LJ, Seo H, Sekiya T, Yoshimura A, Rao A. Abstract A178: Nr4a transcription factors limit CAR T-cell function in solid tumors Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A178  0.492
2019 Chen J, Lopez-Moyado IF, Seo H, Lio CJ, Hempleman LJ, Sekiya T, Yoshimura A, Scott-Browne JP, Rao A. Abstract 937: Nr4a transcription factors limit CAR T-cell function in solid tumors Cancer Research. 79: 937-937. DOI: 10.1158/1538-7445.Am2019-937  0.485
2018 Tuttle KD, Krovi SH, Zhang J, Bedel R, Harmacek L, Peterson LK, Dragone LL, Lefferts A, Halluszczak C, Riemondy K, Hesselberth JR, Rao A, O'Connor BP, Marrack P, Scott-Browne J, et al. TCR signal strength controls thymic differentiation of iNKT cell subsets. Nature Communications. 9: 2650. PMID 29985393 DOI: 10.1038/S41467-018-05026-6  0.616
2018 Bajaj J, Scott-Browne J, Spinler K, Reya T. An In Vivo Genome-Wide CRISPR Screen Identifies Novel Dependencies for Blast Crisis Chronic Myelogenous Leukemia Blood. 132: 1727-1727. DOI: 10.1182/Blood-2018-99-119178  0.313
2017 Marrack P, Krovi SH, Silberman D, White J, Kushnir E, Nakayama M, Crooks J, Danhorn T, Leach S, Anselment R, Scott-Browne J, Gapin L, Kappler J. The somatically generated portion of the T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor. Elife. 6. PMID 29148973 DOI: 10.7554/Elife.30918  0.687
2017 Yu B, Zhang K, Milner JJ, Toma C, Chen R, Scott-Browne JP, Pereira RM, Crotty S, Chang JT, Pipkin ME, Wang W, Goldrath AW. Erratum: Epigenetic landscapes reveal transcription factors that regulate CD8(+) T cell differentiation. Nature Immunology. 18: 705. PMID 28518161 DOI: 10.1038/ni0617-705b  0.314
2017 Yu B, Zhang K, Milner JJ, Toma C, Chen R, Scott-Browne JP, Pereira RM, Crotty S, Chang JT, Pipkin ME, Wang W, Goldrath AW. Epigenetic landscapes reveal transcription factors that regulate CD8(+) T cell differentiation. Nature Immunology. PMID 28288100 DOI: 10.1038/Ni.3706  0.457
2017 Mognol GP, Spreafico R, Wong V, Scott-Browne JP, Togher S, Hoffmann A, Hogan PG, Rao A, Trifari S. Exhaustion-associated regulatory regions in CD8(+) tumor-infiltrating T cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28283662 DOI: 10.1073/Pnas.1620498114  0.47
2017 Tsagaratou A, González-Avalos E, Rautio S, Scott-Browne JP, Togher S, Pastor WA, Rothenberg EV, Chavez L, Lähdesmäki H, Rao A. TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells. Nature Immunology. 18: 45-53. PMID 27869820 DOI: 10.1038/Ni.3630  0.536
2017 Marrack P, Krovi SH, Silberman D, White J, Kushnir E, Nakayama M, Crooks J, Danhorn T, Leach S, Anselment R, Scott-Browne J, Gapin L, Kappler J. Author response: The somatically generated portion of T cell receptor CDR3α contributes to the MHC allele specificity of the T cell receptor Elife. DOI: 10.7554/Elife.30918.028  0.666
2016 Scott-Browne JP, López-Moyado IF, Trifari S, Wong V, Chavez L, Rao A, Pereira RM. Dynamic Changes in Chromatin Accessibility Occur in CD8(+) T Cells Responding to Viral Infection. Immunity. PMID 27939672 DOI: 10.1016/J.Immuni.2016.10.028  0.492
2016 Shaw LA, Bélanger S, Omilusik KD, Cho S, Scott-Browne JP, Nance JP, Goulding J, Lasorella A, Lu LF, Crotty S, Goldrath AW. Id2 reinforces TH1 differentiation and inhibits E2A to repress TFH differentiation. Nature Immunology. PMID 27213691 DOI: 10.1038/Ni.3461  0.46
2013 Young MH, U'Ren L, Huang S, Mallevaey T, Scott-Browne J, Crawford F, Lantz O, Hansen TH, Kappler J, Marrack P, Gapin L. MAIT cell recognition of MR1 on bacterially infected and uninfected cells. Plos One. 8: e53789. PMID 23342002 DOI: 10.1371/Journal.Pone.0053789  0.62
2013 Collins B, Clambey ET, Scott-Browne J, White J, Marrack P, Hagman J, Kappler JW. Ikaros promotes rearrangement of TCR α genes in an Ikaros null thymoma cell line. European Journal of Immunology. 43: 521-32. PMID 23172374 DOI: 10.1002/Eji.201242757  0.597
2012 Yin L, Scott-Browne J, Kappler JW, Gapin L, Marrack P. T cells and their eons-old obsession with MHC. Immunological Reviews. 250: 49-60. PMID 23046122 DOI: 10.1111/Imr.12004  0.671
2012 Lee HM, Bautista JL, Scott-Browne J, Mohan JF, Hsieh CS. A broad range of self-reactivity drives thymic regulatory T cell selection to limit responses to self. Immunity. 37: 475-86. PMID 22921379 DOI: 10.1016/J.Immuni.2012.07.009  0.517
2012 Garcia KC, Gapin L, Adams JJ, Birnbaum ME, Scott-Browne JP, Kappler JW, Marrack P. A closer look at TCR germline recognition. Immunity. 36: 887-8. PMID 22705103 DOI: 10.1016/J.Immuni.2012.05.018  0.544
2011 Scott-Browne JP, Crawford F, Young MH, Kappler JW, Marrack P, Gapin L. Evolutionarily conserved features contribute to αβ T cell receptor specificity. Immunity. 35: 526-35. PMID 21962492 DOI: 10.1016/J.Immuni.2011.09.005  0.665
2011 Yin L, Huseby E, Scott-Browne J, Rubtsova K, Pinilla C, Crawford F, Marrack P, Dai S, Kappler JW. A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers. Immunity. 35: 23-33. PMID 21683626 DOI: 10.1016/J.Immuni.2011.04.017  0.65
2011 Mallevaey T, Clarke AJ, Scott-Browne JP, Young MH, Roisman LC, Pellicci DG, Patel O, Vivian JP, Matsuda JL, McCluskey J, Godfrey DI, Marrack P, Rossjohn J, Gapin L. A molecular basis for NKT cell recognition of CD1d-self-antigen. Immunity. 34: 315-26. PMID 21376640 DOI: 10.1016/J.Immuni.2011.01.013  0.58
2010 Marrack P, Scott-Browne J, MacLeod MK. Terminating the immune response. Immunological Reviews. 236: 5-10. PMID 20636804 DOI: 10.1111/J.1600-065X.2010.00928.X  0.553
2010 Marrack P, Scott-Browne J, White J, Kushnir E, Gapin L, Dai S, Kappler J. The obsession of T cell receptors with MHC (ML06) International Immunology. 22: ii1-ii1. DOI: 10.1093/Intimm/Dxq099  0.632
2009 Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, et al. Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. The Embo Journal. 28: 3781. PMID 19953109 DOI: 10.1038/Emboj.2009.348  0.51
2009 Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, et al. Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands. The Embo Journal. 28: 3579-90. PMID 19816402 DOI: 10.1038/Emboj.2009.286  0.431
2009 Mallevaey T, Scott-Browne JP, Matsuda JL, Young MH, Pellicci DG, Patel O, Thakur M, Kjer-Nielsen L, Richardson SK, Cerundolo V, Howell AR, McCluskey J, Godfrey DI, Rossjohn J, Marrack P, et al. T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire. Immunity. 31: 60-71. PMID 19592274 DOI: 10.1016/J.Immuni.2009.05.010  0.504
2009 Rubtsova K, Scott-Browne JP, Crawford F, Dai S, Marrack P, Kappler JW. Many different Vbeta CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions. Proceedings of the National Academy of Sciences of the United States of America. 106: 7951-6. PMID 19416894 DOI: 10.1073/Pnas.0902728106  0.656
2009 Scott-Browne JP, White J, Kappler JW, Gapin L, Marrack P. Germline-encoded amino acids in the alphabeta T-cell receptor control thymic selection. Nature. 458: 1043-6. PMID 19262510 DOI: 10.1038/Nature07812  0.708
2008 Matsuda JL, Mallevaey T, Scott-Browne J, Gapin L. CD1d-restricted iNKT cells, the 'Swiss-Army knife' of the immune system. Current Opinion in Immunology. 20: 358-68. PMID 18501573 DOI: 10.1016/J.Coi.2008.03.018  0.487
2008 Marrack P, Rubtsova K, Scott-Browne J, Kappler JW. T cell receptor specificity for major histocompatibility complex proteins. Current Opinion in Immunology. 20: 203-7. PMID 18456484 DOI: 10.1016/J.Coi.2008.03.008  0.703
2008 Wun KS, Borg NA, Kjer-Nielsen L, Beddoe T, Koh R, Richardson SK, Thakur M, Howell AR, Scott-Browne JP, Gapin L, Godfrey DI, McCluskey J, Rossjohn J. A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR. The Journal of Experimental Medicine. 205: 939-49. PMID 18378792 DOI: 10.1084/Jem.20072141  0.416
2008 Dai S, Huseby ES, Rubtsova K, Scott-Browne J, Crawford F, Macdonald WA, Marrack P, Kappler JW. Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules. Immunity. 28: 324-34. PMID 18308592 DOI: 10.1016/J.Immuni.2008.01.008  0.675
2008 Marrack P, Scott-Browne JP, Dai S, Gapin L, Kappler JW. Evolutionarily conserved amino acids that control TCR-MHC interaction. Annual Review of Immunology. 26: 171-203. PMID 18304006 DOI: 10.1146/Annurev.Immunol.26.021607.090421  0.666
2007 Scott-Browne JP, Matsuda JL, Mallevaey T, White J, Borg NA, McCluskey J, Rossjohn J, Kappler J, Marrack P, Gapin L. Germline-encoded recognition of diverse glycolipids by natural killer T cells. Nature Immunology. 8: 1105-13. PMID 17828267 DOI: 10.1038/Ni1510  0.577
2007 Scott-Browne JP, Shafiani S, Tucker-Heard G, Ishida-Tsubota K, Fontenot JD, Rudensky AY, Bevan MJ, Urdahl KB. Expansion and function of Foxp3-expressing T regulatory cells during tuberculosis. The Journal of Experimental Medicine. 204: 2159-69. PMID 17709423 DOI: 10.1084/Jem.20062105  0.507
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