Year |
Citation |
Score |
2019 |
Mellal K, Omri S, Mulumba M, Tahiri H, Fortin C, Dorion MF, Pham H, Garcia Ramos Y, Zhang J, Pundir S, Joyal JS, Bouchard JF, Sennlaub F, Febbraio M, Hardy P, ... Gravel SP, et al. Immunometabolic modulation of retinal inflammation by CD36 ligand. Scientific Reports. 9: 12903. PMID 31501473 DOI: 10.1038/S41598-019-49472-8 |
0.343 |
|
2018 |
Hulea L, Gravel SP, Morita M, Cargnello M, Uchenunu O, Im YK, Lehuédé C, Ma EH, Leibovitch M, McLaughlan S, Blouin MJ, Parisotto M, Papavasiliou V, Lavoie C, Larsson O, et al. Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides. Cell Metabolism. PMID 30244971 DOI: 10.1016/J.Cmet.2018.09.001 |
0.39 |
|
2018 |
Shamalnasab M, Gravel SP, St-Pierre J, Breton L, Jäger S, Aguilaniu H. A salicylic acid derivative extends the lifespan of Caenorhabditis elegans by activating autophagy and the mitochondrial unfolded protein response. Aging Cell. e12830. PMID 30192051 DOI: 10.1111/Acel.12830 |
0.375 |
|
2018 |
Im YK, Najyb O, Gravel SP, McGuirk S, Ahn R, Avizonis D, Chénard V, Sabourin V, Hudson J, Pawson T, Topisirovic I, Pollak MN, St-Pierre J, Ursini-Siegel J. Interplay between ShcA signaling and PGC-1α triggers targetable metabolic vulnerabilities in breast cancer. Cancer Research. PMID 29930100 DOI: 10.1158/0008-5472.Can-17-3696 |
0.357 |
|
2018 |
Gravel SP. Deciphering the Dichotomous Effects of PGC-1α on Tumorigenesis and Metastasis. Frontiers in Oncology. 8: 75. PMID 29629336 DOI: 10.3389/Fonc.2018.00075 |
0.367 |
|
2018 |
Houles T, Gravel SP, Lavoie G, Shin S, Savall M, Méant A, Grondin B, Gaboury L, Yoon SO, St-Pierre J, Roux PP. RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma. Cancer Research. PMID 29440170 DOI: 10.1158/0008-5472.Can-17-2215 |
0.501 |
|
2017 |
Rabinovitch RC, Samborska B, Faubert B, Ma EH, Gravel SP, Andrzejewski S, Raissi TC, Pause A, St-Pierre J, Jones RG. AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species. Cell Reports. 21: 1-9. PMID 28978464 DOI: 10.1016/J.Celrep.2017.09.026 |
0.325 |
|
2017 |
Hulea L, Cargnello M, Gravel S, Im Y, McLaughlan S, Zhao Y, Ching J, Cai Y, Larsson O, Ohh M, Ursini-Siegel J, St-Pierre J, Pollak M, Topisirovic I. Abstract A31: eIF4F links translation to energy stress response in cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Transcontrol16-A31 |
0.38 |
|
2016 |
Deblois G, Smith HW, Tam IS, Gravel SP, Caron M, Savage P, Labbé DP, Bégin LR, Tremblay ML, Park M, Bourque G, St-Pierre J, Muller WJ, Giguère V. ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer. Nature Communications. 7: 12156. PMID 27402251 DOI: 10.1038/Ncomms12156 |
0.334 |
|
2016 |
Audet-Walsh É, Papadopoli DJ, Gravel SP, Yee T, Bridon G, Caron M, Bourque G, Giguère V, St-Pierre J. The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer. Cell Reports. PMID 26804918 DOI: 10.1016/J.Celrep.2015.12.086 |
0.364 |
|
2014 |
Gravel SP, Hulea L, Toban N, Birman E, Blouin MJ, Zakikhani M, Zhao Y, Topisirovic I, St-Pierre J, Pollak M. Serine deprivation enhances antineoplastic activity of biguanides. Cancer Research. 74: 7521-33. PMID 25377470 DOI: 10.1158/0008-5472.Can-14-2643-T |
0.429 |
|
2014 |
Andrzejewski S, Gravel S, St-Pierre J, Pollak MN. Dual mode of action of metformin on mitochondrial metabolism Cancer & Metabolism. 2. DOI: 10.1186/2049-3002-2-S1-P4 |
0.315 |
|
2013 |
McGuirk S, Gravel SP, Deblois G, Papadopoli DJ, Faubert B, Wegner A, Hiller K, Avizonis D, Akavia UD, Jones RG, Giguère V, St-Pierre J. PGC-1α supports glutamine metabolism in breast cancer. Cancer & Metabolism. 1: 22. PMID 24304688 DOI: 10.1186/2049-3002-1-22 |
0.304 |
|
2009 |
Gravel S, Richard DE, Servant MJ. Role of the IKK-related kinases in the induction of HIF-1α during hypoxia Cytokine. 48: 54. DOI: 10.1016/J.Cyto.2009.07.159 |
0.663 |
|
2008 |
Clément JF, Bibeau-Poirier A, Gravel SP, Grandvaux N, Bonneil E, Thibault P, Meloche S, Servant MJ. Phosphorylation of IRF-3 on Ser 339 generates a hyperactive form of IRF-3 through regulation of dimerization and CBP association. Journal of Virology. 82: 3984-96. PMID 18272581 DOI: 10.1128/Jvi.02526-07 |
0.681 |
|
2008 |
Gravel S, Richard DE, Servant MJ. 185 IKK-related kinases are repressors of HIF-1 transcriptional activity Cytokine. 43: 283. DOI: 10.1016/J.Cyto.2008.07.247 |
0.698 |
|
2006 |
Bibeau-Poirier A, Gravel SP, Clément JF, Rolland S, Rodier G, Coulombe P, Hiscott J, Grandvaux N, Meloche S, Servant MJ. Involvement of the IkappaB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation. Journal of Immunology (Baltimore, Md. : 1950). 177: 5059-67. PMID 17015689 DOI: 10.4049/Jimmunol.177.8.5059 |
0.684 |
|
2006 |
Douillette A, Bibeau-Poirier A, Gravel SP, Clément JF, Chénard V, Moreau P, Servant MJ. The proinflammatory actions of angiotensin II are dependent on p65 phosphorylation by the IkappaB kinase complex. The Journal of Biological Chemistry. 281: 13275-84. PMID 16513650 DOI: 10.1074/Jbc.M512815200 |
0.665 |
|
2005 |
Gravel SP, Servant MJ. Roles of an IkappaB kinase-related pathway in human cytomegalovirus-infected vascular smooth muscle cells: a molecular link in pathogen-induced proatherosclerotic conditions. The Journal of Biological Chemistry. 280: 7477-86. PMID 15619605 DOI: 10.1074/Jbc.M410392200 |
0.713 |
|
2000 |
Ahnadi CE, Giguère P, Gravel S, Gagné D, Goulet AC, Fülöp T, Payet MD, Dupuis G. Chronic PMA treatment of Jurkat T lymphocytes results in decreased protein tyrosine phosphorylation and inhibition of CD3- but not Ti-dependent antibody-triggered Ca2+ signaling Journal of Leukocyte Biology. 68: 293-300. PMID 10947075 DOI: 10.1189/Jlb.68.2.293 |
0.355 |
|
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