Gary Lopaschuk - Publications

Affiliations: 
University of Alberta, Edmonton, Alberta, Canada 
Area:
Biochemistry, Molecular Biology, Recreation, Public Health

71 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ho KL, Zhang L, Wagg C, Batran RA, Gopal K, Levasseur J, Leone T, Dyck JRB, Ussher JR, Muoio DM, Kelly DP, Lopaschuk GD. Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency. Cardiovascular Research. PMID 30778524 DOI: 10.1093/cvr/cvz045  0.44
2016 Lopaschuk GD, Verma S. Empagliflozin's Fuel Hypothesis: Not so Soon. Cell Metabolism. 24: 200-2. PMID 27508868 DOI: 10.1016/j.cmet.2016.07.018  0.44
2016 Groenendyk J, Lee D, Jung J, Dyck JR, Lopaschuk GD, Agellon LB, Michalak M. Inhibition of the Unfolded Protein Response Mechanism Prevents Cardiac Fibrosis. Plos One. 11: e0159682. PMID 27441395 DOI: 10.1371/journal.pone.0159682  0.44
2016 Akhnokh MK, Yang FH, Samokhvalov V, Jamieson KL, Cho WJ, Wagg C, Takawale A, Wang X, Lopaschuk GD, Hammock BD, Kassiri Z, Seubert JM. Inhibition of Soluble Epoxide Hydrolase Limits Mitochondrial Damage and Preserves Function Following Ischemic Injury. Frontiers in Pharmacology. 7: 133. PMID 27375480 DOI: 10.3389/fphar.2016.00133  0.44
2016 Ussher JR, Fillmore N, Keung W, Zhang L, Mori J, Sidhu VK, Fukushima A, Gopal K, Lopaschuk DG, Wagg CS, Jaswal JS, Dyck JR, Lopaschuk GD. Genetic and pharmacological inhibition of malonyl CoA decarboxylase does not exacerbate age-related insulin resistance in mice. Diabetes. PMID 27207536 DOI: 10.2337/db15-1145  0.44
2015 Azam MA, Wagg CS, Massé S, Farid T, Lai PF, Kusha M, Asta J, Jaimes R, Kuzmiak-Glancy S, Kay MW, Lopaschuk GD, Nanthakumar K. Feeding the fibrillating heart: Dichloroacetate improves cardiac contractile dysfunction following VF. American Journal of Physiology. Heart and Circulatory Physiology. 309: H1543-53. PMID 26342067 DOI: 10.1152/ajpheart.00404.2015  0.44
2015 Masoud WG, Abo Al-Rob O, Yang Y, Lopaschuk GD, Clanachan AS. Tolerance to ischemic injury in remodeled mouse hearts: less ischemic glycogenolysis and preserved metabolic efficiency. Cardiovascular Research. PMID 26150203 DOI: 10.1093/cvr/cvv195  0.6
2015 Lam VH, Zhang L, Huqi A, Fukushima A, Tanner BA, Onay-Besikci A, Keung W, Kantor PF, Jaswal JS, Rebeyka IM, Lopaschuk GD. Activating PPARα Prevents Post-Ischemic Contractile Dysfunction in Hypertrophied Neonatal Hearts. Circulation Research. 117: 41-51. PMID 25977309 DOI: 10.1161/CIRCRESAHA.117.306585  0.44
2015 Gao S, McMillan RP, Zhu Q, Lopaschuk GD, Hulver MW, Butler AA. Therapeutic effects of adropin on glucose tolerance and substrate utilization in diet-induced obese mice with insulin resistance. Molecular Metabolism. 4: 310-24. PMID 25830094 DOI: 10.1016/j.molmet.2015.01.005  0.44
2015 Fillmore N, Keung W, Kelly SE, Proctor SD, Lopaschuk GD, Ussher JR. Accumulation of ceramide in slow-twitch muscle contributes to the development of insulin resistance in the obese JCR:LA-cp rat. Experimental Physiology. 100: 730-41. PMID 25786668 DOI: 10.1113/EP085052  0.44
2015 Fillmore N, Huqi A, Jaswal JS, Mori J, Paulin R, Haromy A, Onay-Besikci A, Ionescu L, Thébaud B, Michelakis E, Lopaschuk GD. Effect of fatty acids on human bone marrow mesenchymal stem cell energy metabolism and survival. Plos One. 10: e0120257. PMID 25768019 DOI: 10.1371/journal.pone.0120257  0.68
2014 Wu R, Chang HC, Khechaduri A, Chawla K, Tran M, Chai X, Wagg C, Ghanefar M, Jiang X, Bayeva M, Gonzalez F, Lopaschuk G, Ardehali H. Cardiac-specific ablation of ARNT leads to lipotoxicity and cardiomyopathy. The Journal of Clinical Investigation. 124: 4795-806. PMID 25329697 DOI: 10.1172/JCI76737  0.44
2014 Aksentijević D, McAndrew DJ, Karlstädt A, Zervou S, Sebag-Montefiore L, Cross R, Douglas G, Regitz-Zagrosek V, Lopaschuk GD, Neubauer S, Lygate CA. Cardiac dysfunction and peri-weaning mortality in malonyl-coenzyme A decarboxylase (MCD) knockout mice as a consequence of restricting substrate plasticity. Journal of Molecular and Cellular Cardiology. 75: 76-87. PMID 25066696 DOI: 10.1016/j.yjmcc.2014.07.008  0.44
2014 Ussher JR, Fillmore N, Keung W, Mori J, Beker DL, Wagg CS, Jaswal JS, Lopaschuk GD. Trimetazidine therapy prevents obesity-induced cardiomyopathy in mice. The Canadian Journal of Cardiology. 30: 940-4. PMID 25064584 DOI: 10.1016/j.cjca.2014.04.023  0.44
2014 Ezekowitz JA, Becher H, Belenkie I, Clark AM, Duff HJ, Friedrich MG, Haykowsky MJ, Howlett JG, Kassiri Z, Kaul P, Kim DH, Knudtson ML, Light PE, Lopaschuk GD, McAlister FA, et al. The Alberta Heart Failure Etiology and Analysis Research Team (HEART) study. Bmc Cardiovascular Disorders. 14: 91. PMID 25063541 DOI: 10.1186/1471-2261-14-91  0.44
2014 Gao S, McMillan RP, Jacas J, Zhu Q, Li X, Kumar GK, Casals N, Hegardt FG, Robbins PD, Lopaschuk GD, Hulver MW, Butler AA. Regulation of substrate oxidation preferences in muscle by the peptide hormone adropin. Diabetes. 63: 3242-52. PMID 24848071 DOI: 10.2337/db14-0388  0.44
2014 Ussher JR, Keung W, Fillmore N, Koves TR, Mori J, Zhang L, Lopaschuk DG, Ilkayeva OR, Wagg CS, Jaswal JS, Muoio DM, Lopaschuk GD. Treatment with the 3-ketoacyl-CoA thiolase inhibitor trimetazidine does not exacerbate whole-body insulin resistance in obese mice. The Journal of Pharmacology and Experimental Therapeutics. 349: 487-96. PMID 24700885 DOI: 10.1124/jpet.114.214197  0.44
2014 Mori J, Patel VB, Ramprasath T, Alrob OA, DesAulniers J, Scholey JW, Lopaschuk GD, Oudit GY. Angiotensin 1-7 mediates renoprotection against diabetic nephropathy by reducing oxidative stress, inflammation, and lipotoxicity. American Journal of Physiology. Renal Physiology. 306: F812-21. PMID 24553436 DOI: 10.1152/ajprenal.00655.2013  0.44
2014 Mori J, Patel VB, Abo Alrob O, Basu R, Altamimi T, Desaulniers J, Wagg CS, Kassiri Z, Lopaschuk GD, Oudit GY. Angiotensin 1-7 ameliorates diabetic cardiomyopathy and diastolic dysfunction in db/db mice by reducing lipotoxicity and inflammation. Circulation. Heart Failure. 7: 327-39. PMID 24389129 DOI: 10.1161/CIRCHEARTFAILURE.113.000672  0.44
2014 Masoud WG, Ussher JR, Wang W, Jaswal JS, Wagg CS, Dyck JR, Lygate CA, Neubauer S, Clanachan AS, Lopaschuk GD. Failing mouse hearts utilize energy inefficiently and benefit from improved coupling of glycolysis and glucose oxidation. Cardiovascular Research. 101: 30-8. PMID 24048945 DOI: 10.1093/cvr/cvt216  0.44
2013 Gao S, Moran TH, Lopaschuk GD, Butler AA. Hypothalamic malonyl-CoA and the control of food intake. Physiology & Behavior. 122: 17-24. PMID 23988346 DOI: 10.1016/j.physbeh.2013.07.014  0.44
2013 Zhang L, Jaswal JS, Ussher JR, Sankaralingam S, Wagg C, Zaugg M, Lopaschuk GD. Cardiac insulin-resistance and decreased mitochondrial energy production precede the development of systolic heart failure after pressure-overload hypertrophy. Circulation. Heart Failure. 6: 1039-48. PMID 23861485 DOI: 10.1161/CIRCHEARTFAILURE.112.000228  0.44
2013 Gao S, Serra D, Keung W, Hegardt FG, Lopaschuk GD. Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake. American Journal of Physiology. Endocrinology and Metabolism. 305: E336-47. PMID 23736540 DOI: 10.1152/ajpendo.00168.2013  0.44
2013 Dolinsky VW, Chakrabarti S, Pereira TJ, Oka T, Levasseur J, Beker D, Zordoky BN, Morton JS, Nagendran J, Lopaschuk GD, Davidge ST, Dyck JR. Resveratrol prevents hypertension and cardiac hypertrophy in hypertensive rats and mice. Biochimica Et Biophysica Acta. 1832: 1723-33. PMID 23707558 DOI: 10.1016/j.bbadis.2013.05.018  0.44
2013 Gao S, Casals N, Keung W, Moran TH, Lopaschuk GD. Differential effects of central ghrelin on fatty acid metabolism in hypothalamic ventral medial and arcuate nuclei. Physiology & Behavior. 118: 165-70. PMID 23680429 DOI: 10.1016/j.physbeh.2013.03.030  0.44
2013 Lee D, Oka T, Hunter B, Robinson A, Papp S, Nakamura K, Srisakuldee W, Nickel BE, Light PE, Dyck JR, Lopaschuk GD, Kardami E, Opas M, Michalak M. Calreticulin induces dilated cardiomyopathy. Plos One. 8: e56387. PMID 23437120 DOI: 10.1371/journal.pone.0056387  0.44
2013 Mori J, Alrob OA, Wagg CS, Harris RA, Lopaschuk GD, Oudit GY. ANG II causes insulin resistance and induces cardiac metabolic switch and inefficiency: a critical role of PDK4. American Journal of Physiology. Heart and Circulatory Physiology. 304: H1103-13. PMID 23396452 DOI: 10.1152/ajpheart.00636.2012  0.44
2013 Gill RS, Lee TF, Manouchehri N, Liu JQ, Lopaschuk G, Bigam DL, Cheung PY. Postresuscitation cyclosporine treatment attenuates myocardial and cardiac mitochondrial injury in newborn piglets with asphyxia-reoxygenation. Critical Care Medicine. 41: 1069-74. PMID 23385100 DOI: 10.1097/CCM.0b013e3182746704  0.44
2013 Singh KK, Shukla PC, Yanagawa B, Quan A, Lovren F, Pan Y, Wagg CS, Teoh H, Lopaschuk GD, Verma S. Regulating cardiac energy metabolism and bioenergetics by targeting the DNA damage repair protein BRCA1. The Journal of Thoracic and Cardiovascular Surgery. 146: 702-9. PMID 23317938 DOI: 10.1016/j.jtcvs.2012.12.046  0.44
2013 Piao L, Sidhu VK, Fang YH, Ryan JJ, Parikh KS, Hong Z, Toth PT, Morrow E, Kutty S, Lopaschuk GD, Archer SL. FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate. Journal of Molecular Medicine (Berlin, Germany). 91: 333-46. PMID 23247844 DOI: 10.1007/s00109-012-0982-0  0.44
2013 Wu G, Zhang L, Li T, Zuniga A, Lopaschuk GD, Li L, Jacobs RL, Vance DE. Choline supplementation promotes hepatic insulin resistance in phosphatidylethanolamine N-methyltransferase-deficient mice via increased glucagon action. The Journal of Biological Chemistry. 288: 837-47. PMID 23179947 DOI: 10.1074/jbc.M112.415117  0.44
2013 Keung W, Ussher JR, Jaswal JS, Raubenheimer M, Lam VH, Wagg CS, Lopaschuk GD. Inhibition of carnitine palmitoyltransferase-1 activity alleviates insulin resistance in diet-induced obese mice. Diabetes. 62: 711-20. PMID 23139350 DOI: 10.2337/db12-0259  0.44
2013 Lewandowski ED, Fischer SK, Fasano M, Banke NH, Walker LA, Huqi A, Wang X, Lopaschuk GD, O'Donnell JM. Acute liver carnitine palmitoyltransferase I overexpression recapitulates reduced palmitate oxidation of cardiac hypertrophy. Circulation Research. 112: 57-65. PMID 22982985 DOI: 10.1161/CIRCRESAHA.112.274456  0.44
2012 Samokhvalov V, Ussher JR, Fillmore N, Armstrong IK, Keung W, Moroz D, Lopaschuk DG, Seubert J, Lopaschuk GD. Inhibition of malonyl-CoA decarboxylase reduces the inflammatory response associated with insulin resistance. American Journal of Physiology. Endocrinology and Metabolism. 303: E1459-68. PMID 23074239 DOI: 10.1152/ajpendo.00018.2012  0.44
2012 Cherian S, Lopaschuk GD, Carvalho E. Cellular cross-talk between epicardial adipose tissue and myocardium in relation to the pathogenesis of cardiovascular disease. American Journal of Physiology. Endocrinology and Metabolism. 303: E937-49. PMID 22895783 DOI: 10.1152/ajpendo.00061.2012  0.44
2012 Wu G, Zhang L, Li T, Lopaschuk G, Vance DE, Jacobs RL. Choline Deficiency Attenuates Body Weight Gain and Improves Glucose Tolerance in ob/ob Mice. Journal of Obesity. 2012: 319172. PMID 22778916 DOI: 10.1155/2012/319172  0.44
2012 Ussher JR, Folmes CD, Keung W, Fillmore N, Jaswal JS, Cadete VJ, Beker DL, Lam VH, Zhang L, Lopaschuk GD. Inhibition of serine palmitoyl transferase I reduces cardiac ceramide levels and increases glycolysis rates following diet-induced insulin resistance. Plos One. 7: e37703. PMID 22629445 DOI: 10.1371/journal.pone.0037703  0.44
2012 Zhang L, Mori J, Wagg C, Lopaschuk GD. Activating cardiac E2F1 induces up-regulation of pyruvate dehydrogenase kinase 4 in mice on a short term of high fat feeding. Febs Letters. 586: 996-1003. PMID 22569253 DOI: 10.1016/j.febslet.2012.02.027  0.44
2012 Cadete VJ, Sawicka J, Jaswal JS, Lopaschuk GD, Schulz R, Szczesna-Cordary D, Sawicki G. Ischemia/reperfusion-induced myosin light chain 1 phosphorylation increases its degradation by matrix metalloproteinase 2. The Febs Journal. 279: 2444-54. PMID 22564771 DOI: 10.1111/j.1742-4658.2012.08622.x  0.44
2012 Ussher JR, Wang W, Gandhi M, Keung W, Samokhvalov V, Oka T, Wagg CS, Jaswal JS, Harris RA, Clanachan AS, Dyck JR, Lopaschuk GD. Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury. Cardiovascular Research. 94: 359-69. PMID 22436846 DOI: 10.1093/cvr/cvs129  0.44
2012 Oka T, Lam VH, Zhang L, Keung W, Cadete VJ, Samokhvalov V, Tanner BA, Beker DL, Ussher JR, Huqi A, Jaswal JS, Rebeyka IM, Lopaschuk GD. Cardiac hypertrophy in the newborn delays the maturation of fatty acid β-oxidation and compromises postischemic functional recovery. American Journal of Physiology. Heart and Circulatory Physiology. 302: H1784-94. PMID 22408020 DOI: 10.1152/ajpheart.00804.2011  0.44
2011 Keung W, Palaniyappan A, Lopaschuk GD. Chronic central leptin decreases food intake and improves glucose tolerance in diet-induced obese mice independent of hypothalamic malonyl CoA levels and skeletal muscle insulin sensitivity. Endocrinology. 152: 4127-37. PMID 21914780 DOI: 10.1210/en.2011-1254  0.44
2011 Gao S, Zhu G, Gao X, Wu D, Carrasco P, Casals N, Hegardt FG, Moran TH, Lopaschuk GD. Important roles of brain-specific carnitine palmitoyltransferase and ceramide metabolism in leptin hypothalamic control of feeding. Proceedings of the National Academy of Sciences of the United States of America. 108: 9691-6. PMID 21593415 DOI: 10.1073/pnas.1103267108  0.44
2011 Gao S, Keung W, Serra D, Wang W, Carrasco P, Casals N, Hegardt FG, Moran TH, Lopaschuk GD. Malonyl-CoA mediates leptin hypothalamic control of feeding independent of inhibition of CPT-1a. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 301: R209-17. PMID 21508288 DOI: 10.1152/ajpregu.00092.2011  0.44
2011 Jaswal JS, Keung W, Wang W, Ussher JR, Lopaschuk GD. Targeting fatty acid and carbohydrate oxidation--a novel therapeutic intervention in the ischemic and failing heart. Biochimica Et Biophysica Acta. 1813: 1333-50. PMID 21256164 DOI: 10.1016/j.bbamcr.2011.01.015  0.44
2011 Odenbach J, Wang X, Cooper S, Chow FL, Oka T, Lopaschuk G, Kassiri Z, Fernandez-Patron C. MMP-2 mediates angiotensin II-induced hypertension under the transcriptional control of MMP-7 and TACE. Hypertension. 57: 123-30. PMID 21079048 DOI: 10.1161/HYPERTENSIONAHA.110.159525  0.44
2011 Keung W, Cadete VJ, Palaniyappan A, Jablonski A, Fischer M, Lopaschuk GD. Intracerebroventricular leptin administration differentially alters cardiac energy metabolism in mice fed a low-fat and high-fat diet. Journal of Cardiovascular Pharmacology. 57: 103-13. PMID 20980918 DOI: 10.1097/FJC.0b013e31820014f9  0.44
2011 Zhang L, Ussher JR, Oka T, Cadete VJ, Wagg C, Lopaschuk GD. Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation. Cardiovascular Research. 89: 148-56. PMID 20729341 DOI: 10.1093/cvr/cvq266  0.44
2010 Sutendra G, Bonnet S, Rochefort G, Haromy A, Folmes KD, Lopaschuk GD, Dyck JR, Michelakis ED. Fatty acid oxidation and malonyl-CoA decarboxylase in the vascular remodeling of pulmonary hypertension. Science Translational Medicine. 2: 44ra58. PMID 20702857 DOI: 10.1126/scitranslmed.3001327  0.44
2010 Dolinsky VW, Morton JS, Oka T, Robillard-Frayne I, Bagdan M, Lopaschuk GD, Des Rosiers C, Walsh K, Davidge ST, Dyck JR. Calorie restriction prevents hypertension and cardiac hypertrophy in the spontaneously hypertensive rat. Hypertension. 56: 412-21. PMID 20696994 DOI: 10.1161/HYPERTENSIONAHA.110.154732  0.44
2010 Wang L, Ko KW, Lucchinetti E, Zhang L, Troxler H, Hersberger M, Omar MA, Posse de Chaves EI, Lopaschuk GD, Clanachan AS, Zaugg M. Metabolic profiling of hearts exposed to sevoflurane and propofol reveals distinct regulation of fatty acid and glucose oxidation: CD36 and pyruvate dehydrogenase as key regulators in anesthetic-induced fuel shift. Anesthesiology. 113: 541-51. PMID 20683255 DOI: 10.1097/ALN.0b013e3181e2c1a1  0.6
2010 Jaswal JS, Lund CR, Keung W, Beker DL, Rebeyka IM, Lopaschuk GD. Isoproterenol stimulates 5'-AMP-activated protein kinase and fatty acid oxidation in neonatal hearts. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1135-45. PMID 20656883 DOI: 10.1152/ajpheart.00186.2010  0.44
2010 Folmes CD, Sawicki G, Cadete VJ, Masson G, Barr AJ, Lopaschuk GD. Novel O-palmitolylated beta-E1 subunit of pyruvate dehydrogenase is phosphorylated during ischemia/reperfusion injury. Proteome Science. 8: 38. PMID 20618950 DOI: 10.1186/1477-5956-8-38  0.44
2010 Scott JM, Esch BT, Haykowsky MJ, Paterson I, Warburton DE, Chow K, Cheng Baron J, Lopaschuk GD, Thompson RB. Effects of high intensity exercise on biventricular function assessed by cardiac magnetic resonance imaging in endurance trained and normally active individuals. The American Journal of Cardiology. 106: 278-83. PMID 20599016 DOI: 10.1016/j.amjcard.2010.02.037  0.44
2010 Ussher JR, Koves TR, Cadete VJ, Zhang L, Jaswal JS, Swyrd SJ, Lopaschuk DG, Proctor SD, Keung W, Muoio DM, Lopaschuk GD. Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption. Diabetes. 59: 2453-64. PMID 20522596 DOI: 10.2337/db09-1293  0.44
2010 Jessen N, Koh HJ, Folmes CD, Wagg C, Fujii N, Løfgren B, Wolf CM, Berul CI, Hirshman MF, Lopaschuk GD, Goodyear LJ. Ablation of LKB1 in the heart leads to energy deprivation and impaired cardiac function. Biochimica Et Biophysica Acta. 1802: 593-600. PMID 20441792 DOI: 10.1016/j.bbadis.2010.04.008  0.44
2010 Niu W, Bilan PJ, Ishikura S, Schertzer JD, Contreras-Ferrat A, Fu Z, Liu J, Boguslavsky S, Foley KP, Liu Z, Li J, Chu G, Panakkezhum T, Lopaschuk GD, Lavandero S, et al. Contraction-related stimuli regulate GLUT4 traffic in C2C12-GLUT4myc skeletal muscle cells. American Journal of Physiology. Endocrinology and Metabolism. 298: E1058-71. PMID 20159855 DOI: 10.1152/ajpendo.00773.2009  0.44
2010 Lopaschuk GD, Ussher JR, Folmes CD, Jaswal JS, Stanley WC. Myocardial fatty acid metabolism in health and disease. Physiological Reviews. 90: 207-58. PMID 20086077 DOI: 10.1152/physrev.00015.2009  0.44
2010 Piao L, Fang YH, Cadete VJ, Wietholt C, Urboniene D, Toth PT, Marsboom G, Zhang HJ, Haber I, Rehman J, Lopaschuk GD, Archer SL. The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle. Journal of Molecular Medicine (Berlin, Germany). 88: 47-60. PMID 19949938 DOI: 10.1007/s00109-009-0524-6  0.44
2010 Zhang L, Keung W, Samokhvalov V, Wang W, Lopaschuk GD. Role of fatty acid uptake and fatty acid beta-oxidation in mediating insulin resistance in heart and skeletal muscle. Biochimica Et Biophysica Acta. 1801: 1-22. PMID 19782765 DOI: 10.1016/j.bbalip.2009.09.014  0.44
2009 Ussher JR, Jaswal JS, Wagg CS, Armstrong HE, Lopaschuk DG, Keung W, Lopaschuk GD. Role of the atypical protein kinase Czeta in regulation of 5'-AMP-activated protein kinase in cardiac and skeletal muscle. American Journal of Physiology. Endocrinology and Metabolism. 297: E349-57. PMID 19625676 DOI: 10.1152/ajpendo.00009.2009  0.44
2009 Wang X, Oka T, Chow FL, Cooper SB, Odenbach J, Lopaschuk GD, Kassiri Z, Fernandez-Patron C. Tumor necrosis factor-alpha-converting enzyme is a key regulator of agonist-induced cardiac hypertrophy and fibrosis. Hypertension. 54: 575-82. PMID 19581512 DOI: 10.1161/HYPERTENSIONAHA.108.127670  0.44
2009 Ussher JR, Koves TR, Jaswal JS, Zhang L, Ilkayeva O, Dyck JR, Muoio DM, Lopaschuk GD. Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet-induced obese mice lacking malonyl CoA decarboxylase. Diabetes. 58: 1766-75. PMID 19478144 DOI: 10.2337/db09-0011  0.44
2007 Onay-Besikci A, Wagg C, Lopaschuk TP, Keung W, Lopaschuk GD. Alpha-lipoic acid increases cardiac glucose oxidation independent of AMP-activated protein kinase in isolated working rat hearts. Basic Research in Cardiology. 102: 436-44. PMID 17530314 DOI: 10.1007/s00395-007-0661-4  0.44
2004 Onay-Besikci A, Altarejos JY, Lopaschuk GD. gAd-globular head domain of adiponectin increases fatty acid oxidation in newborn rabbit hearts. The Journal of Biological Chemistry. 279: 44320-6. PMID 15269215 DOI: 10.1074/jbc.M400347200  0.68
2003 Onay-Besikci A, Campbell FM, Hopkins TA, Dyck JR, Lopaschuk GD, Onay Besikci A. Relative importance of malonyl CoA and carnitine in maturation of fatty acid oxidation in newborn rabbit heart. American Journal of Physiology. Heart and Circulatory Physiology. 284: H283-9. PMID 12388233 DOI: 10.1152/ajpheart.00461.2002  0.68
2002 Liu Q, Docherty JC, Rendell JC, Clanachan AS, Lopaschuk GD. High levels of fatty acids delay the recovery of intracellular pH and cardiac efficiency in post-ischemic hearts by inhibiting glucose oxidation. Journal of the American College of Cardiology. 39: 718-25. PMID 11849874  0.6
1998 Fraser H, Lopaschuk GD, Clanachan AS. Assessment of glycogen turnover in aerobic, ischemic, and reperfused working rat hearts. American Journal of Physiology. Heart and Circulatory Physiology. 275: H1533-H1541. PMID 29592216 DOI: 10.1152/ajpheart.1998.275.5.H1533  0.6
1998 Ford WR, Clanachan AS, Lopaschuk GD, Schulz R, Jugdutt BI. Intrinsic ANG II type 1 receptor stimulation contributes to recovery of postischemic mechanical function. American Journal of Physiology. Heart and Circulatory Physiology. 274: H1524-H1531. PMID 29586502 DOI: 10.1152/ajpheart.1998.274.5.H1524  0.6
1998 Liu Q, Clanachan AS, Lopaschuk GD. Acute effects of triiodothyronine on glucose and fatty acid metabolism during reperfusion of ischemic rat hearts. American Journal of Physiology. Endocrinology and Metabolism. 275: E392-E399. PMID 29585551 DOI: 10.1152/ajpendo.1998.275.3.E392  0.6
1998 Liu Q, Clanachan AS, Lopaschuk GD. Acute effects of triiodothyronine on glucose and fatty acid metabolism during reperfusion of ischemic rat hearts. The American Journal of Physiology. 275: E392-9. PMID 9725804  0.6
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