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Raman V. Chirakal - Publications

Affiliations: 
Radiology McMaster University, Hamilton, ON, Canada 
Area:
Radiation Chemistry
Website:
http://www.chemistry.mcmaster.ca/chirakal/
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Azad BB, Ashique R, Labiris NR, Chirakal R. Temperature effects on the stereospecificity of nucleophilic fluorination: formation of trans‐[18F]4‐fluoro‐l‐proline during the synthesis of cis‐[18F]4‐fluoro‐l‐proline Journal of Labelled Compounds and Radiopharmaceuticals. 55: 23-28. DOI: 10.1002/Jlcr.1947  0.595
2010 Vasdev N, Moran MD, Tuononen HM, Chirakal R, Suontamo RJ, Bain AD, Schrobilgen GJ. NMR spectroscopic evidence for the intermediacy of XeF(3)(-) in XeF(2)/F(-) exchange, attempted syntheses and thermochemistry of XeF(3)(-) salts, and theoretical studies of the XeF(3)(-) anion. Inorganic Chemistry. 49: 8997-9004. PMID 20799721 DOI: 10.1021/Ic101275M  0.773
2010 Vasdev N, Chirakal R, Schrobilgen GJ, Nahmias C. ChemInform Abstract: Selectivity of Elemental Fluorine Towards L-Tyrosine and L-α-Methyltyrosine in Acidic Media and the Syntheses of Their [18F]3-Fluoro and [18F]3,5-Difluoro Derivatives. Cheminform. 33: no-no. DOI: 10.1002/CHIN.200220158  0.733
2009 Ashique R, Chirakal R, Schrobilgen GJ, Hughes DW, Farncombe T, Gulenchyn K, Labiris R, Truman T, Saab C. Reactivity and selectivity of F2 toward 3,4,6-Tri-O-acetyl-D-Glucal in anhydrous HF: Synthesis of [18F]2-fluoro-2-deoxy-β- D-allose and its use for the detection of a breast tumor Acs Symposium Series. 1003: 211-235. DOI: 10.1021/bk-2009-1003.ch010  0.595
2008 Jager PL, Chirakal R, Marriott CJ, Brouwers AH, Koopmans KP, Gulenchyn KY. 6-L-18F-fluorodihydroxyphenylalanine PET in neuroendocrine tumors: basic aspects and emerging clinical applications. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 573-86. PMID 18344441 DOI: 10.2967/Jnumed.107.045708  0.509
2008 Behnam Azad B, Ashique R, Chirakal R, Schrobilgen GJ. Selective fluorination of m-tyrosine by OF2 Journal of Fluorine Chemistry. 129: 22-27. DOI: 10.1016/J.Jfluchem.2007.08.004  0.732
2007 Azad BB, Chirakal R, Schrobilgen GJ. Trifluoromethanesulfonic acid, an alternative solvent medium for the direct electrophilic fluorination of DOPA: New syntheses of 6-[18F]fluoro- L-DOPA and 6-[18F]fluoro-D-DOPA Journal of Labelled Compounds and Radiopharmaceuticals. 50: 1236-1242. DOI: 10.1002/Jlcr.1454  0.768
2006 Guenther KJ, Yoganathan S, Garofalo R, Kawabata T, Strack T, Labiris R, Dolovich M, Chirakal R, Valliant JF. Synthesis and in vitro evaluation of 18F- and 19F-labeled insulin: a new radiotracer for PET-based molecular imaging studies. Journal of Medicinal Chemistry. 49: 1466-74. PMID 16480283 DOI: 10.1021/Jm0509344  0.394
2006 Ashique R, Chirakal RV, Hughes DW, Schrobilgen GJ. Two-step regio- and stereoselective syntheses of [19F]- and [18F]-2-deoxy-2-(R)-fluoro-beta-D-allose. Carbohydrate Research. 341: 457-66. PMID 16413000 DOI: 10.1016/J.Carres.2005.12.002  0.664
2004 Mamo D, Remington G, Nobrega J, Hussey D, Chirakal R, Wilson AA, Baker G, Houle S, Kapur S. Effect of acute antipsychotic administration on dopamine synthesis in rodents and human subjects using 6-[18F]-L-m-tyrosine. Synapse (New York, N.Y.). 52: 153-62. PMID 15034921 DOI: 10.1002/Syn.20016  0.474
2003 Mamo D, Chirakal R, Wilson A, Hussey D, Kapur S. The effect of single-dose risperidone on aromatic amino acid decar☐ylase activity in healthy human subjects measured using [18F]6-fluoro-L-M-tyrosine positron emission tomography Schizophrenia Research. 60: 243. DOI: 10.1016/S0920-9964(03)81251-3  0.493
2003 Vasdev N, Chirakal R, Ashique R, Schrobilgen GJ, Gulenchyn K. Syntheses of [18F]5-fluoro-3-nitro-L-tyrosine Journal of Fluorine Chemistry. 121: 9-14. DOI: 10.1016/S0022-1139(02)00334-2  0.801
2002 Vasdev N, Pointner BE, Chirakal R, Schrobilgen GJ. On the preparation of fluorine-18 labelled XeF(2) and chemical exchange between fluoride ion and XeF(2). Journal of the American Chemical Society. 124: 12863-8. PMID 12392433 DOI: 10.1021/Ja020604Y  0.768
2002 Vasdev N, Pointner BE, Chirakal R, Schrobilgen GJ. On the preparation of fluorine-18 labelled XeF2 and chemical exchange between fluoride ion and XeF2 Journal of the American Chemical Society. 124: 12863-12868. DOI: 10.1021/ja020604y  0.603
2002 Chirakal R, Vasdev N, Asselin MC, Schrobilgen GJ, Nahmias C. The effect of aromatic fluorine substitution in L-DOPA on the in vivo behaviour of [18F]2-, [18F]5- and [18F]6-fluoro-L-DOPA in the human brain Journal of Fluorine Chemistry. 115: 33-39. DOI: 10.1016/S0022-1139(02)00025-8  0.795
2001 Vasdev N, Chirakal R, Schrobilgen GJ, Nahmias C. Selectivity of elemental fluorine towards L-tyrosine and L-α-methyltyrosine in acidic media and the syntheses of their [18F]3-fluoro and [18F]3,5-difluoro derivatives Journal of Fluorine Chemistry. 111: 17-25. DOI: 10.1016/S0022-1139(01)00406-7  0.754
2001 Chirakal R, Vasdev N, Schrobilgen GJ, Amano S, Nahmias C. A comparative study of the in vivo behaviour of [18F] 2-, 5- and 6-fluoro-L-dopa in the human brain Journal of Labelled Compounds and Radiopharmaceuticals. 44: S219-S221. DOI: 10.1002/Jlcr.2580440176  0.751
2001 Vasdev N, Chirakal R, Schrobilgen GJ, Nahmias C. Selectivity of [18F]F2 towards L-α-methyltyrosine and L-tyrosine: A radiochemical and NMR spectroscopic study Journal of Labelled Compounds and Radiopharmaceuticals. 44: S863-S865. DOI: 10.1002/Jlcr.25804401303  0.784
1999 Wahl LM, Chen JJ, Thompson M, Chirakal R, Nahmias C. The time course of metabolites in human plasma after 6-[18F]fluoro-L-m-tyrosine administration European Journal of Nuclear Medicine. 26: 1407-1412. PMID 10552081 DOI: 10.1007/S002590050472  0.45
1999 Fallen EL, Coates G, Nahmias C, Chirakal R, Beanlands R, Wahl L, Woodcock G, Thomson M, Kamath M. Recovery rates of regional sympathetic reinnervation and myocardial blood flow after acute myocardial infarction American Heart Journal. 137: 863-869. PMID 10220635 DOI: 10.1016/S0002-8703(99)70410-2  0.338
1999 Chirakal R, Vasdev N, Schrobilgen GJ, Nahmias C. Radiochemical and NMR spectroscopic investigation of the solvent effect on the electrophilic elemental fluorination of L-DOPA: Synthesis of [ 18F ]5-fluoro-L-DOPA Journal of Fluorine Chemistry. 99: 87-94. DOI: 10.1016/S0022-1139(99)00123-2  0.726
1998 Lui E, Chirakal R, Firnau G. Enzymatic synthesis of (−)-6-[18F]-fluoronorepinephrine from 6-[18F]-fluorodopamine by dopamine β-hydroxylase Journal of Labelled Compounds and Radiopharmaceuticals. 41: 503-521. DOI: 10.1002/(Sici)1099-1344(199806)41:6<503::Aid-Jlcr107>3.0.Co;2-I  0.611
1996 Chirakal R, Coates G, Firnau G, Schrobilgen GJ, Nahmias C. Direct radiofluorination of dopamine: 18F-labeled 6-fluorodopamine for imaging cardiac sympathetic innervation in humans using positron emission tomography. Nuclear Medicine and Biology. 23: 41-5. PMID 9004913 DOI: 10.1016/0969-8051(95)00213-8  0.732
1996 Coates G, Chirakal R, Fallen EL, Firnau G, Garnett ES, Kamath MV, Scheffel A, Nahmias C. Regional distribution and kinetics of [18F]6-flurodopamine as a measure of cardiac sympathetic activity in humans Heart. 75: 29-34. PMID 8624867 DOI: 10.1136/Hrt.75.1.29  0.603
1995 Chirakal R, Adams RM, Firnau G, Schrobilgen GJ, Coates G, Garnett ES. Electrophilic 18F from a Siemens 11 MeV proton-only cyclotron. Nuclear Medicine and Biology. 22: 111-6. PMID 7735160 DOI: 10.1016/0969-8051(94)E0064-P  0.692
1995 Nahmias C, Wahl L, Chirakal R, Firnau G, Garnett ES. A probe for intracerebral aromatic amino-acid decarboxylase activity: Distribution and kinetics of [18F]6-fluoro-L-m-tyrosine in the human brain Movement Disorders. 10: 298-304. PMID 7651447 DOI: 10.1002/Mds.870100312  0.532
1995 Chirakal R, McCarry B, Lonegran M, Firnau G, Garnett S. Base-mediated decomposition of a Mannose triflate during the synthesis of 2-deoxy-2-18F-fluoro-d-glucose Applied Radiation and Isotopes. 46: 149-155. DOI: 10.1016/0969-8043(94)00128-M  0.6
1994 Wahl L, Chirakal R, Firnau G, Garnett ES, Nahmias C. The distribution and kinetics of [18F]6-Fluoro-3-O-methyl-L-dopa in the human brain Journal of Cerebral Blood Flow and Metabolism. 14: 664-670. PMID 8014214 DOI: 10.1038/Jcbfm.1994.83  0.544
1991 Chirakal R, Schrobilgen GJ, Firnau G, Garnett S. Synthesis of 18F labelled fluoro-m-tyrosine, fluoro-m-tyramine and fluoro-3-hydroxyphenylacetic acid International Journal of Radiation Applications and Instrumentation. Part. 42: 113-119. DOI: 10.1016/0883-2889(91)90059-A  0.713
1990 Firnau G, Chirakal R, Nahmias C, Brown K, Garnett ES. New 18F tracers for the investigation of brain functions Acta Radiologica, Supplement. 374: 37-41. PMID 1966968  0.546
1990 Christe KO, Wilson WW, Chirakal RV, Sanders JCP, Schrobilgen GJ. The hexafluorochlorate(V) anion, ClF6 - Inorganic Chemistry. 29: 3506-3511. DOI: 10.1021/Ic00343A044  0.668
1990 CHRISTE KO, WILSON WW, CHIRAKAL RV, SANDERS JCP, SCHROBILGEN GJ. ChemInform Abstract: The Hexafluorochlorate(V) Anion, ClF- 6. Cheminform. 21. DOI: 10.1002/chin.199048022  0.404
1989 Chirakal R, Firnau G, Garnett E, Schrobilgen G. Direct elemental fluorination of tyrosine in HF and HF/BF3. Reactivity and selectivity Journal of Fluorine Chemistry. 45: 125. DOI: 10.1016/S0022-1139(00)84497-8  0.577
1989 Chirakal R, Firnau G, Garnett E. A positron emitting inhibitor of aromatic L-aminoacid decarboxylase: α-fluoromethyl-6-[F-18]fluoro-L-DOPA Journal of Labelled Compounds and Radiopharmaceuticals. 26: 228-229. DOI: 10.1002/Jlcr.25802601103  0.578
1988 Firnau G, Sood S, Chirakal R, Nahmias C, Garnett ES. Metabolites of 6-[18F]fluoro-L-dopa in human blood Journal of Nuclear Medicine. 29: 363-369. PMID 3126278  0.598
1988 Christe KO, Wilson WW, Schrobilgen GJ, Chirakal RV, Olah GA. On the existence of pentacoordinated nitrogen Inorganic Chemistry. 27: 789-790. DOI: 10.1021/Ic00278A009  0.506
1988 Christe KO, Wilson WW, Schrobilgen GJ, Chirakal RV, Olah GA. On the existence of pentacoordinated nitrogen Inorganic Chemistry. 27: 789-790. DOI: 10.1021/ic00278a009  0.364
1988 Chirakal R, Firnau G, Garnett E. Sequential production of electrophilic and nucleophilic fluorinating agents from [18F]fluorine gas International Journal of Radiation Applications and Instrumentation. Part a. Applied Radiation and Isotopes. 39: 1099-1101. DOI: 10.1016/0883-2889(88)90149-9  0.626
1988 Chirakal R, Sayer BG, Firnau G, Garnett ES. Synthesis of f-18 labelled fluoro-melatonins and 5-hydroxy-fluoro-tryptophans Journal of Labelled Compounds and Radiopharmaceuticals. 25: 63-71. DOI: 10.1002/Jlcr.2580250108  0.521
1987 Garnett ES, Lang AE, Chirakal R, Firnau G, Nahmias C. A rostrocaudal gradient for aromatic acid decarboxylase in the human striatum Canadian Journal of Neurological Sciences. 14: 444-447. PMID 3119181 DOI: 10.1017/S0317167100037884  0.556
1987 Firnau G, Sood S, Chirakal R, Nahmias C, Garnett ES. Cerebral Metabolism of 6–[18F]Fluoro‐l‐3,4‐Dihydroxyphenylalanine in the Primate Journal of Neurochemistry. 48: 1077-1082. PMID 3102690 DOI: 10.1111/J.1471-4159.1987.Tb05629.X  0.608
1987 Chirakal R, Brown K, Firnau G, Garnett E, Hughes D, Sayer B, Smith R. Synthesis of 2- and 3-fluorotyrosine with dilute fluorine gas Journal of Fluorine Chemistry. 37: 267-278. DOI: 10.1016/S0022-1139(00)82023-0  0.557
1986 Firnau G, Garnett ES, Chirakal R, Sood S, Nahmias C, Schrobilgen G. [18F]fluoro-L-dopa for the in vivo study of intracerebral dopamine. International Journal of Radiation Applications and Instrumentation. Part a, Applied Radiation and Isotopes. 37: 669-75. PMID 3021668 DOI: 10.1016/0883-2889(86)90260-1  0.69
1984 Chirakal R, Firnau G, Couse J, Garnett E. Radiofluorination with 18F-labelled acetyl hypofluorite: [18F]L-6-fluorodopa The International Journal of Applied Radiation and Isotopes. 35: 651-653. DOI: 10.1016/0020-708X(84)90111-X  0.661
1984 Chirakal R, Firnau G, Schrobilgen GJ, Mckay J, Garnett ES. The synthesis of [18F]Xenon difluoride from [18F]fluoride gas The International Journal of Applied Radiation and Isotopes. 35: 401-404. DOI: 10.1016/0020-708X(84)90049-8  0.743
1983 Garnett S, Firnau G, Nahmias C, Chirakal R. Striatal dopamine metabolism in living monkeys examined by positron emission tomography Brain Research. 280: 169-171. PMID 6418330 DOI: 10.1016/0006-8993(83)91187-3  0.564
1981 Firnau GSG, Chirakal R, Garnett ES. Synthesis of [18F]XeF2, a novel agent for the preparation of 18F-radiopharmaceuticals Journal of the Chemical Society, Chemical Communications. 198-199. DOI: 10.1039/C39810000198  0.648
1981 SCHROBILGEN G, FIRNAU G, CHIRAKAL R, GARNETT ES. ChemInform Abstract: SYNTHESIS OF XENON DIFLUORIDE-18F, A NOVEL AGENT FOR THE PREPARATION OF FLUORINE-18 RADIOPHARMACEUTICALS Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198125038  0.685
1980 Firnau G, Chirakal R, Sood S, Garnett S. Aromatic fluorination with xenon difluoride: L-3,4-dihydroxy-6-fluoro-phenylalanine Canadian Journal of Chemistry. 58: 1449-1450. DOI: 10.1139/V80-228  0.433
1980 FIRANAU G, CHIRAKAL R, SOOD S, GARNETT S. ChemInform Abstract: AROMATIC FLUORINATION OF XENON DIFLUORIDE: L-3,4-DIHYDROXY-6-FLUORO-PHENYLALANINE Chemischer Informationsdienst. 11. DOI: 10.1002/Chin.198048294  0.452
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