| Year |
Citation |
Score |
| 2021 |
Morrow NM, Trzaskalski NA, Hanson AA, Fadzeyeva E, Telford DE, Chhoker SS, Sutherland BG, Edwards JY, Huff MW, Mulvihill EE. Nobiletin Prevents High-Fat Diet-Induced Dysregulation of Intestinal Lipid Metabolism and Attenuates Postprandial Lipemia. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA121316896. PMID 34911361 DOI: 10.1161/ATVBAHA.121.316896 |
0.336 |
|
| 2020 |
Morrow NM, Burke AC, Samsoondar JP, Seigel KE, Wang A, Telford DE, Sutherland BG, O'Dwyer C, Steinberg GR, Fullerton MD, Huff MW. The citrus flavonoid nobiletin confers protection from metabolic dysregulation in high-fat fed- mice independent of AMPK. Journal of Lipid Research. PMID 31964763 DOI: 10.1194/Jlr.Ra119000542 |
0.377 |
|
| 2019 |
Burke AC, Sutherland BG, Telford DE, Morrow MR, Sawyez CG, Edwards JY, Huff MW. Naringenin enhances the regression of atherosclerosis induced by a chow diet in Ldlr mice. Atherosclerosis. 286: 60-70. PMID 31102954 DOI: 10.1016/J.Atherosclerosis.2019.05.009 |
0.384 |
|
| 2019 |
Burke AC, Telford DE, Huff MW. Bempedoic acid: effects on lipoprotein metabolism and atherosclerosis. Current Opinion in Lipidology. 30: 1-9. PMID 30586346 DOI: 10.1097/Mol.0000000000000565 |
0.417 |
|
| 2018 |
Burke AC, Telford DE, Edwards JY, Sutherland BG, Sawyez CG, Huff MW. Naringenin Supplementation to a Chow Diet Enhances Energy Expenditure and Fatty Acid Oxidation, and Reduces Adiposity in Lean, Pair-Fed Ldlr Mice. Molecular Nutrition & Food Research. e1800833. PMID 30578663 DOI: 10.1002/Mnfr.201800833 |
0.371 |
|
| 2018 |
Burke AC, Sutherland BG, Telford DE, Morrow MR, Sawyez CG, Edwards JY, Drangova M, Huff MW. Intervention with citrus flavonoids reverses obesity, and improves metabolic syndrome and atherosclerosis in obese Ldlr-/- mice. Journal of Lipid Research. PMID 30008441 DOI: 10.1194/Jlr.M087387 |
0.313 |
|
| 2018 |
Burke AC, Telford DE, Sutherland BG, Edwards JY, Sawyez CG, Barrett PHR, Newton RS, Pickering JG, Huff MW. Bempedoic Acid Lowers Low-Density Lipoprotein Cholesterol and Attenuates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient (and) Yucatan Miniature Pigs. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29449335 DOI: 10.1161/Atvbaha.117.310676 |
0.473 |
|
| 2018 |
Morrow NM, Huff MW. Knockdown of Δ-5 Fatty Acid Desaturase Is More Than Just a Fad. Arteriosclerosis, Thrombosis, and Vascular Biology. 38: 6-8. PMID 29282245 DOI: 10.1161/Atvbaha.117.310382 |
0.32 |
|
| 2018 |
Morrow NM, Telford DE, Sutherland BG, Edwards JY, Huff MW. Nobiletin Corrects Intestinal Lipid Metabolism in Ldlr-/- Mice Fed a High-Fat Diet Atherosclerosis Supplements. 32: 28. DOI: 10.1016/J.Atherosclerosissup.2018.04.081 |
0.377 |
|
| 2018 |
Burke AC, Telford DE, Edwards JY, Sutherland BG, Morrow MR, Sawyez CG, Huff MW. Naringenin Supplementation to a Chow Diet Enhances Energy Expenditure and Fatty Acid Oxidation, and Reduces Adiposity in Ldlr-/- Mice with Isocaloric Food Intake Atherosclerosis Supplements. 32: 23. DOI: 10.1016/J.Atherosclerosissup.2018.04.068 |
0.307 |
|
| 2017 |
Samsoondar JP, Burke AC, Sutherland BG, Telford DE, Sawyez CG, Edwards JY, Pinkosky SL, Newton RS, Huff MW. Prevention of Diet-Induced Metabolic Dysregulation, Inflammation, and Atherosclerosis in Ldlr-/- Mice by Treatment With the ATP-Citrate Lyase Inhibitor Bempedoic Acid. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28153881 DOI: 10.1161/Atvbaha.116.308963 |
0.428 |
|
| 2017 |
Burke AC, Huff MW. ATP-citrate lyase: genetics, molecular biology and therapeutic target for dyslipidemia. Current Opinion in Lipidology. PMID 28059952 DOI: 10.1097/Mol.0000000000000390 |
0.333 |
|
| 2016 |
Burke AC, Dron JS, Hegele RA, Huff MW. PCSK9: Regulation and Target for Drug Development for Dyslipidemia. Annual Review of Pharmacology and Toxicology. PMID 27575716 DOI: 10.1146/Annurev-Pharmtox-010716-104944 |
0.414 |
|
| 2016 |
Mulvihill EE, Burke AC, Huff MW. Citrus Flavonoids as Regulators of Lipoprotein Metabolism and Atherosclerosis. Annual Review of Nutrition. PMID 27146015 DOI: 10.1146/Annurev-Nutr-071715-050718 |
0.382 |
|
| 2015 |
Assini JM, Mulvihill EE, Burke AC, Sutherland BG, Telford DE, Chhoker SS, Sawyez CG, Drangova M, Adams AC, Kharitonenkov A, Pin CL, Huff MW. Naringenin prevents obesity, hepatic steatosis, and glucose intolerance in male mice independent of fibroblast growth factor 21. Endocrinology. 156: 2087-102. PMID 25774553 DOI: 10.1210/En.2014-2003 |
0.342 |
|
| 2015 |
Huff MW, Pickering JG. Can a vascular smooth muscle-derived foam-cell really change its spots? Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 492-5. PMID 25717175 DOI: 10.1161/Atvbaha.115.305225 |
0.406 |
|
| 2015 |
Hussain Y, Ding Q, Connelly PW, Brunt JH, Ban MR, McIntyre AD, Huff MW, Gros R, Hegele RA, Feldman RD. G-protein estrogen receptor as a regulator of low-density lipoprotein cholesterol metabolism: cellular and population genetic studies. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 213-21. PMID 25395619 DOI: 10.1161/Atvbaha.114.304326 |
0.444 |
|
| 2014 |
Huff MW, Assini JM, Hegele RA. Gene therapy for hypercholesterolemia: sweet dreams and flying machines. Circulation Research. 115: 542-5. PMID 25170090 DOI: 10.1161/Circresaha.114.304800 |
0.454 |
|
| 2014 |
Bojic LA, Telford DE, Fullerton MD, Ford RJ, Sutherland BG, Edwards JY, Sawyez CG, Gros R, Kemp BE, Steinberg GR, Huff MW. PPARδ activation attenuates hepatic steatosis in Ldlr-/- mice by enhanced fat oxidation, reduced lipogenesis, and improved insulin sensitivity. Journal of Lipid Research. 55: 1254-1266. PMID 24864274 DOI: 10.1194/Jlr.M046037 |
0.426 |
|
| 2014 |
Bojic LA, Burke AC, Chhoker SS, Telford DE, Sutherland BG, Edwards JY, Sawyez CG, Tirona RG, Yin H, Pickering JG, Huff MW. Peroxisome proliferator-activated receptor δ agonist GW1516 attenuates diet-induced aortic inflammation, insulin resistance, and atherosclerosis in low-density lipoprotein receptor knockout mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 52-60. PMID 24158519 DOI: 10.1161/Atvbaha.113.301830 |
0.375 |
|
| 2013 |
Huff MW, Hegele RA. Apolipoprotein C-III: going back to the future for a lipid drug target. Circulation Research. 112: 1405-8. PMID 23704213 DOI: 10.1161/Circresaha.113.301464 |
0.421 |
|
| 2013 |
Bojic LA, Huff MW. Peroxisome proliferator-activated receptor δ: a multifaceted metabolic player. Current Opinion in Lipidology. 24: 171-7. PMID 23481229 DOI: 10.1097/Mol.0B013E32835Cc949 |
0.307 |
|
| 2013 |
Assini JM, Mulvihill EE, Sutherland BG, Telford DE, Sawyez CG, Felder SL, Chhoker S, Edwards JY, Gros R, Huff MW. Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr⁻/⁻ mice. Journal of Lipid Research. 54: 711-24. PMID 23269394 DOI: 10.1194/jlr.M032631 |
0.38 |
|
| 2012 |
Beyea MM, Reaume S, Sawyez CG, Edwards JY, O'Neil C, Hegele RA, Pickering JG, Huff MW. The oxysterol 24(s),25-epoxycholesterol attenuates human smooth muscle-derived foam cell formation via reduced low-density lipoprotein uptake and enhanced cholesterol efflux. Journal of the American Heart Association. 1: e000810. PMID 23130136 DOI: 10.1161/Jaha.112.000810 |
0.387 |
|
| 2012 |
Bojic LA, Sawyez CG, Telford DE, Edwards JY, Hegele RA, Huff MW. Activation of peroxisome proliferator-activated receptor δ inhibits human macrophage foam cell formation and the inflammatory response induced by very low-density lipoprotein. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2919-28. PMID 23023367 DOI: 10.1161/Atvbaha.112.255208 |
0.432 |
|
| 2012 |
Mulvihill EE, Huff MW. Protection from Metabolic Dysregulation, Obesity, and Atherosclerosis by Citrus Flavonoids: Activation of Hepatic PGC1α-Mediated Fatty Acid Oxidation. Ppar Research. 2012: 857142. PMID 22701469 DOI: 10.1155/2012/857142 |
0.357 |
|
| 2011 |
Johansen CT, Wang J, Lanktree MB, McIntyre AD, Ban MR, Martins RA, Kennedy BA, Hassell RG, Visser ME, Schwartz SM, Voight BF, Elosua R, Salomaa V, O'Donnell CJ, Dallinga-Thie GM, ... ... Huff MW, et al. An increased burden of common and rare lipid-associated risk alleles contributes to the phenotypic spectrum of hypertriglyceridemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1916-26. PMID 21597005 DOI: 10.1161/Atvbaha.111.226365 |
0.304 |
|
| 2011 |
Mulvihill EE, Assini JM, Lee JK, Allister EM, Sutherland BG, Koppes JB, Sawyez CG, Edwards JY, Telford DE, Charbonneau A, St-Pierre P, Marette A, Huff MW. Nobiletin attenuates VLDL overproduction, dyslipidemia, and atherosclerosis in mice with diet-induced insulin resistance. Diabetes. 60: 1446-57. PMID 21471511 DOI: 10.2337/Db10-0589 |
0.362 |
|
| 2010 |
Mulvihill EE, Huff MW. Antiatherogenic properties of flavonoids: implications for cardiovascular health. The Canadian Journal of Cardiology. 26: 17A-21A. PMID 20386755 DOI: 10.1016/S0828-282X(10)71056-4 |
0.306 |
|
| 2010 |
Mulvihill EE, Assini JM, Sutherland BG, DiMattia AS, Khami M, Koppes JB, Sawyez CG, Whitman SC, Huff MW. Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat-fed low-density lipoprotein receptor-null mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 742-8. PMID 20110573 DOI: 10.1161/Atvbaha.109.201095 |
0.452 |
|
| 2010 |
Lahiry P, Cao H, Ban MR, Pollex RL, Mamakeesick M, Zinman B, Harris SB, Hanley AJ, Huff MW, Connelly PW, Hegele RA. APOC1 T45S polymorphism is associated with reduced obesity indices and lower plasma concentrations of leptin and apolipoprotein C-I in aboriginal Canadians. Journal of Lipid Research. 51: 843-8. PMID 19812053 DOI: 10.1194/Jlr.P002014 |
0.359 |
|
| 2009 |
Mulvihill EE, Allister EM, Sutherland BG, Telford DE, Sawyez CG, Edwards JY, Markle JM, Hegele RA, Huff MW. Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance. Diabetes. 58: 2198-210. PMID 19592617 DOI: 10.2337/Db09-0634 |
0.347 |
|
| 2009 |
Frontini MJ, O'Neil C, Sawyez C, Chan BM, Huff MW, Pickering JG. Lipid incorporation inhibits Src-dependent assembly of fibronectin and type I collagen by vascular smooth muscle cells. Circulation Research. 104: 832-41. PMID 19229059 DOI: 10.1161/Circresaha.108.187302 |
0.354 |
|
| 2008 |
Allister EM, Mulvihill EE, Barrett PH, Edwards JY, Carter LP, Huff MW. Inhibition of apoB secretion from HepG2 cells by insulin is amplified by naringenin, independent of the insulin receptor. Journal of Lipid Research. 49: 2218-29. PMID 18587069 DOI: 10.1194/Jlr.M800297-Jlr200 |
0.345 |
|
| 2008 |
Telford DE, Huff MW. Postprandial hyperlipidemia: Cardiovascular implications and treatment options Canadian Journal of Cardiology. 24: 32C-37C. DOI: 10.1016/S0828-282X(08)71036-5 |
0.429 |
|
| 2007 |
Beyea MM, Heslop CL, Sawyez CG, Edwards JY, Markle JG, Hegele RA, Huff MW. Selective up-regulation of LXR-regulated genes ABCA1, ABCG1, and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol. The Journal of Biological Chemistry. 282: 5207-16. PMID 17186944 DOI: 10.1074/Jbc.M611063200 |
0.429 |
|
| 2007 |
Telford DE, Sutherland BG, Edwards JY, Andrews JD, Barrett PH, Huff MW. The molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin. Journal of Lipid Research. 48: 699-708. PMID 17130282 DOI: 10.1194/Jlr.M600439-Jlr200 |
0.494 |
|
| 2006 |
Burnett JR, Huff MW. Cholesterol absorption inhibitors as a therapeutic option for hypercholesterolaemia. Expert Opinion On Investigational Drugs. 15: 1337-51. PMID 17040195 DOI: 10.1517/13543784.15.11.1337 |
0.409 |
|
| 2005 |
Burnett JR, Telford DE, Barrett PH, Huff MW. The ACAT inhibitor avasimibe increases the fractional clearance rate of postprandial triglyceride-rich lipoproteins in miniature pigs. Biochimica Et Biophysica Acta. 1738: 10-8. PMID 16427354 DOI: 10.1016/J.Bbalip.2005.11.010 |
0.436 |
|
| 2005 |
Telford DE, Lipson SM, Barrett PH, Sutherland BG, Edwards JY, Aebi JD, Dehmlow H, Morand OH, Huff MW. A novel inhibitor of oxidosqualene:lanosterol cyclase inhibits very low-density lipoprotein apolipoprotein B100 (apoB100) production and enhances low-density lipoprotein apoB100 catabolism through marked reduction in hepatic cholesterol content. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 2608-14. PMID 16210564 DOI: 10.1161/01.Atv.0000189158.28455.94 |
0.474 |
|
| 2005 |
Huff MW, Telford DE. Lord of the rings--the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear. Trends in Pharmacological Sciences. 26: 335-40. PMID 15951028 DOI: 10.1016/J.Tips.2005.05.004 |
0.459 |
|
| 2005 |
Allister EM, Borradaile NM, Edwards JY, Huff MW. Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation of the mitogen-activated protein kinase pathway in hepatocytes. Diabetes. 54: 1676-83. PMID 15919788 DOI: 10.2337/Diabetes.54.6.1676 |
0.703 |
|
| 2005 |
Argmann CA, Edwards JY, Sawyez CG, O'Neil CH, Hegele RA, Pickering JG, Huff MW. Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux. The Journal of Biological Chemistry. 280: 22212-21. PMID 15817453 DOI: 10.1074/Jbc.M502761200 |
0.719 |
|
| 2004 |
Argmann CA, Sawyez CG, Li S, Nong Z, Hegele RA, Pickering JG, Huff MW. Human smooth muscle cell subpopulations differentially accumulate cholesteryl ester when exposed to native and oxidized lipoproteins. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1290-6. PMID 15130914 DOI: 10.1161/01.Atv.0000131260.80316.37 |
0.595 |
|
| 2004 |
Argmann CA, Sawyez CG, LI S, Hegele RA, Pickering J, Huff MW. HUMAN ARTERIAL SMOOTH MUSCLE CELL SUB-POPULATIONS ARE DIFFERENTIALLY CONVERTED ITNO FOAM CELLS BY NATIVE AND OXIDIZED LIPOPROTEINS Cardiovascular Pathology. 13: 157. DOI: 10.1016/j.carpath.2004.03.474 |
0.565 |
|
| 2003 |
Huff MW. Dietary cholesterol, cholesterol absorption, postprandial lipemia and atherosclerosis. The Canadian Journal of Clinical Pharmacology = Journal Canadien De Pharmacologie Clinique. 10: 26A-32A. PMID 14571303 |
0.418 |
|
| 2003 |
Borradaile NM, de Dreu LE, Huff MW. Inhibition of net HepG2 cell apolipoprotein B secretion by the citrus flavonoid naringenin involves activation of phosphatidylinositol 3-kinase, independent of insulin receptor substrate-1 phosphorylation. Diabetes. 52: 2554-61. PMID 14514640 DOI: 10.2337/Diabetes.52.10.2554 |
0.71 |
|
| 2003 |
Rowe AH, Argmann CA, Edwards JY, Sawyez CG, Morand OH, Hegele RA, Huff MW. Enhanced synthesis of the oxysterol 24(S),25-epoxycholesterol in macrophages by inhibitors of 2,3-oxidosqualene:lanosterol cyclase: a novel mechanism for the attenuation of foam cell formation. Circulation Research. 93: 717-25. PMID 14512442 DOI: 10.1161/01.Res.0000097606.43659.F4 |
0.668 |
|
| 2003 |
Argmann CA, Sawyez CG, McNeil CJ, Hegele RA, Huff MW. Activation of peroxisome proliferator-activated receptor gamma and retinoid X receptor results in net depletion of cellular cholesteryl esters in macrophages exposed to oxidized lipoproteins. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 475-82. PMID 12615696 DOI: 10.1161/01.Atv.0000058860.62870.6E |
0.632 |
|
| 2003 |
Borradaile NM, de Dreu LE, Barrett PH, Behrsin CD, Huff MW. Hepatocyte apoB-containing lipoprotein secretion is decreased by the grapefruit flavonoid, naringenin, via inhibition of MTP-mediated microsomal triglyceride accumulation. Biochemistry. 42: 1283-91. PMID 12564931 DOI: 10.1021/Bi026731O |
0.753 |
|
| 2003 |
Telford DE, Edwards JY, Lipson SM, Sutherland B, Barrett PH, Burnett JR, Krul ES, Keller BT, Huff MW. Inhibition of both the apical sodium-dependent bile acid transporter and HMG-CoA reductase markedly enhances the clearance of LDL apoB. Journal of Lipid Research. 44: 943-52. PMID 12562847 DOI: 10.1194/Jlr.M200482-Jlr200 |
0.493 |
|
| 2002 |
Huff MW, Telford DE, Edwards JY, Burnett JR, Barrett PH, Rapp SR, Napawan N, Keller BT. Inhibition of the apical sodium-dependent bile acid transporter reduces LDL cholesterol and apoB by enhanced plasma clearance of LDL apoB. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1884-91. PMID 12426220 DOI: 10.1161/01.Atv.0000035390.87288.26 |
0.44 |
|
| 2002 |
Borradaile NM, de Dreu LE, Barrett PH, Huff MW. Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters. Journal of Lipid Research. 43: 1544-54. PMID 12235187 DOI: 10.1194/Jlr.M200115-Jlr200 |
0.725 |
|
| 2002 |
Borradaile NM, de Dreu LE, Wilcox LJ, Edwards JY, Huff MW. Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms. The Biochemical Journal. 366: 531-9. PMID 12030847 DOI: 10.1042/Bj20020046 |
0.764 |
|
| 2001 |
Argmann CA, Van Den Diepstraten CH, Sawyez CG, Edwards JY, Hegele RA, Wolfe BM, Huff MW. Transforming growth factor-beta1 inhibits macrophage cholesteryl ester accumulation induced by native and oxidized VLDL remnants. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 2011-8. PMID 11742878 DOI: 10.1161/Hq1201.099426 |
0.622 |
|
| 2001 |
Wilcox LJ, Borradaile NM, de Dreu LE, Huff MW. Secretion of hepatocyte apoB is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP. Journal of Lipid Research. 42: 725-34. PMID 11352979 |
0.747 |
|
| 2000 |
Wolfe BM, Barrett PH, Laurier L, Huff MW. Effects of continuous conjugated estrogen and micronized progesterone therapy upon lipoprotein metabolism in postmenopausal women. Journal of Lipid Research. 41: 368-75. PMID 10706584 |
0.355 |
|
| 2000 |
Burnett JR, Barrett PHR, Telford DE, Huff MW. The ACAT inhibitor avasimibe increases the fractional clearance rate of postprandial triglyceride-rich lipoproteins Atherosclerosis. 151: 134. DOI: 10.1016/S0021-9150(00)80607-3 |
0.408 |
|
| 1999 |
Burnett JR, Wilcox LJ, Telford DE, Kleinstiver SJ, Barrett PH, Newton RS, Huff MW. The magnitude of decrease in hepatic very low density lipoprotein apolipoprotein B secretion is determined by the extent of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibition in miniature pigs. Endocrinology. 140: 5293-302. PMID 10537160 DOI: 10.1210/Endo.140.11.7150 |
0.487 |
|
| 1999 |
Burnett JR, Wilcox LJ, Huff MW. Acyl coenzyme A: cholesterol acyltransferase inhibition and hepatic apolipoprotein B secretion. Clinica Chimica Acta; International Journal of Clinical Chemistry. 286: 231-42. PMID 10511295 DOI: 10.1016/S0009-8981(99)00104-7 |
0.474 |
|
| 1999 |
Burnett JR, Wilcox LJ, Telford DE, Kleinstiver SJ, Barrett PH, Newton RS, Huff MW. Inhibition of ACAT by avasimibe decreases both VLDL and LDL apolipoprotein B production in miniature pigs. Journal of Lipid Research. 40: 1317-27. PMID 10393217 |
0.402 |
|
| 1999 |
Wilcox LJ, Barrett PH, Huff MW. Differential regulation of apolipoprotein B secretion from HepG2 cells by two HMG-CoA reductase inhibitors, atorvastatin and simvastatin. Journal of Lipid Research. 40: 1078-89. PMID 10357840 |
0.349 |
|
| 1999 |
Whitman SC, Argmann CA, Sawyez CG, Miller DB, Hegele RA, Huff MW. Uptake of type IV hypertriglyceridemic VLDL by cultured macrophages is enhanced by interferon-gamma. Journal of Lipid Research. 40: 1017-28. PMID 10357833 |
0.643 |
|
| 1999 |
Whitman SC, Hazen SL, Miller DB, Hegele RA, Heinecke JW, Huff MW. Modification of type III VLDL, their remnants, and VLDL from ApoE-knockout mice by p-hydroxyphenylacetaldehyde, a product of myeloperoxidase activity, causes marked cholesteryl ester accumulation in macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 1238-49. PMID 10323775 DOI: 10.1161/01.Atv.19.5.1238 |
0.453 |
|
| 1999 |
Wilcox LJ, Barrett PH, Newton RS, Huff MW. ApoB100 secretion from HepG2 cells is decreased by the ACAT inhibitor CI-1011: an effect associated with enhanced intracellular degradation of ApoB. Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 939-49. PMID 10195921 DOI: 10.1161/01.Atv.19.4.939 |
0.401 |
|
| 1999 |
Wilcox LJ, Borradaile NM, Huff MW. Antiatherogenic Properties of Naringenin, a Citrus Flavonoid Cardiovascular Drug Reviews. 17: 160-178. DOI: 10.1111/J.1527-3466.1999.Tb00011.X |
0.633 |
|
| 1998 |
Burnett JR, Barrett PH, Vicini P, Miller DB, Telford DE, Kleinstiver SJ, Huff MW. The HMG-CoA reductase inhibitor atorvastatin increases the fractional clearance rate of postprandial triglyceride-rich lipoproteins in miniature pigs. Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 1906-14. PMID 9848883 DOI: 10.1161/01.Atv.18.12.1906 |
0.329 |
|
| 1998 |
Burnett JR, Wilcox LJ, Telford DE, Kleinstiver SJ, Barrett PH, Huff MW. Inhibition of cholesterol esterification by DuP 128 decreases hepatic apolipoprotein B secretion in vivo: effect of dietary fat and cholesterol. Biochimica Et Biophysica Acta. 1393: 63-79. PMID 9714740 DOI: 10.1016/S0005-2760(98)00059-9 |
0.508 |
|
| 1997 |
Burnett JR, Wilcox LJ, Telford DE, Kleinstiver SJ, Barrett PH, Newton RS, Huff MW. Inhibition of HMG-CoA reductase by atorvastatin decreases both VLDL and LDL apolipoprotein B production in miniature pigs. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 2589-600. PMID 9409231 DOI: 10.1161/01.Atv.17.11.2589 |
0.504 |
|
| 1997 |
Kang AK, Jenkins DJA, Wolever TMS, Huff MW, Maguire GF, Connelly PW, Hegele RA. Apolipoprotein E R112; R251G: A carboxy-terminal variant found in patients with hyperlipidemia and coronary heart disease Mutation Research - Mutation Research Genomics. 382: 57-65. PMID 9360638 DOI: 10.1016/S1383-5726(97)00009-5 |
0.308 |
|
| 1997 |
Whitman SC, Miller DB, Wolfe BM, Hegele RA, Huff MW. Uptake of type III hypertriglyceridemic VLDL by macrophages is enhanced by oxidation, especially after remnant formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 1707-15. PMID 9327767 DOI: 10.1161/01.Atv.17.9.1707 |
0.322 |
|
| 1997 |
Huff MW, Miller DB, Wolfe BM, Connelly PW, Sawyez CG. Uptake of hypertriglyceridemic very low density lipoproteins and their remnants by HepG2 cells: The role of lipoprotein lipase, hepatic triglyceride lipase, and cell surface proteoglycans Journal of Lipid Research. 38: 1318-1333. PMID 9254059 |
0.317 |
|
| 1997 |
Huff MW, Burnett JR. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and hepatic apolipoprotein B secretion. Current Opinion in Lipidology. 8: 138-45. PMID 9211061 DOI: 10.1097/00041433-199706000-00003 |
0.443 |
|
| 1997 |
Burnett J, Wilcox L, Telford D, Kleinstiver S, Barrett P, Newton R, Huff M. 4.P.251 Inhibition of ACAT by CI-1011, in vivo, decreases both VLDL and LDL apoB production in the miniature pig Atherosclerosis. 134: 348-349. DOI: 10.1016/S0021-9150(97)89779-1 |
0.347 |
|
| 1997 |
Huff M, Whitman S, Hazen S, Heinecke J, Miller D, Hegele R. 3.P.115 Modification of type III VLDL, their remnants and VLDL from apoE-knockout mice by p-hydroxyphenylacetaldehyde, causes marked macrophage cholesteryl ester accumulation Atherosclerosis. 134: 222. DOI: 10.1016/S0021-9150(97)89189-7 |
0.304 |
|
| 1996 |
Cianflone K, Avramoglu RK, Sawyez C, Huff MW. Inhibition of lipoprotein lipase induced cholesterol ester accumulation in human hepatoma HepG2 cells. Atherosclerosis. 120: 101-14. PMID 8645351 DOI: 10.1016/0021-9150(95)05690-4 |
0.507 |
|
| 1995 |
Wolfe BM, Huff MW. Effects of continuous low-dosage hormonal replacement therapy on lipoprotein metabolism in postmenopausal women. Metabolism: Clinical and Experimental. 44: 410-7. PMID 7885290 DOI: 10.1016/0026-0495(95)90175-2 |
0.458 |
|
| 1995 |
Miller DB, Hegele RA, Wolfe BM, Huff MW. Identification, molecular characterization, and cellular studies of an apolipoprotein E mutant (E1) in three unrelated families with hyperlipidemia. The Journal of Clinical Endocrinology and Metabolism. 80: 807-13. PMID 7883834 DOI: 10.1210/Jcem.80.3.7883834 |
0.311 |
|
| 1995 |
Ingram AJ, Parbtani A, Clark WF, Spanner E, Huff MW, Philbrick DJ, Holub BJ. Effects of flaxseed and flax oil diets in a rat-5/6 renal ablation model American Journal of Kidney Diseases. 25: 320-329. PMID 7847360 DOI: 10.1016/0272-6386(95)90015-2 |
0.33 |
|
| 1995 |
Clark WF, Parbtani A, Huff MW, Spanner E, de Salis H, Chin-Yee I, Philbrick DJ, Holub BJ. Flaxseed: a potential treatment for lupus nephritis. Kidney International. 48: 475-80. PMID 7564115 DOI: 10.1038/Ki.1995.316 |
0.303 |
|
| 1994 |
Huff MW, Telford DE, Barrett PH, Billheimer JT, Gillies PJ. Inhibition of hepatic ACAT decreases ApoB secretion in miniature pigs fed a cholesterol-free diet. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 14: 1498-508. PMID 8068612 DOI: 10.1161/01.Atv.14.9.1498 |
0.5 |
|
| 1994 |
Rabkin SW, Huff MW, Newman C, Sim D, Carruthers SG. Lipids and lipoproteins during antihypertensive drug therapy. Comparison of doxazosin and atenolol in a randomized, double-blind trial: the Alpha Beta Canada Study. Hypertension (Dallas, Tex. : 1979). 24: 241-8. PMID 8039850 DOI: 10.1161/01.Hyp.24.2.241 |
0.321 |
|
| 1994 |
Huff M, Wolfe B, Sawyez C. Enhanced uptake of hypertriglyceridemic VLDL by HepG2 cells requires active lipoprotein lipase and subsequent remnant uptake requires cell surface proteoglycans Atherosclerosis. 109: 66-67. DOI: 10.1016/0021-9150(94)93280-8 |
0.338 |
|
| 1993 |
Evans AJ, Sawyez CG, Wolfe BM, Connelly PW, Maguire GF, Huff MW. Evidence that cholesteryl ester and triglyceride accumulation in J774 macrophages induced by very low density lipoprotein subfractions occurs by different mechanisms Journal of Lipid Research. 34: 703-717. PMID 8509711 |
0.38 |
|
| 1993 |
Evans AJ, Wolfe BM, Strong WL, Huff MW. Reduced lipolysis of large apo E-poor very-low-density lipoprotein subfractions from type IV hypertriglyceridemic subjects in vitro and in vivo. Metabolism: Clinical and Experimental. 42: 105-15. PMID 8446037 DOI: 10.1016/0026-0495(93)90180-V |
0.369 |
|
| 1993 |
Huff MW, Sawyez CG, Connelly PW, Maguire GF, Alick Little J, Hegele RA. β-VLDL in hepatic lipase deficiency induces ApoE-mediated cholesterol ester accumulation in macrophages Arteriosclerosis, Thrombosis, and Vascular Biology. 13: 1282-1290. PMID 8364012 DOI: 10.1161/01.Atv.13.9.1282 |
0.374 |
|
| 1993 |
Huff MW, Telford DE, Edmonds BW, McDonald CG, Evans AJ. Lipoprotein lipases, lipoprotein density gradient profile and LDL receptor activity in miniature pigs fed fish oil and corn oil. Biochimica Et Biophysica Acta. 1210: 113-22. PMID 8257713 DOI: 10.1016/0005-2760(93)90056-F |
0.448 |
|
| 1992 |
Huff MW, Telford DE, Barrett PH. Dietary fish oil plus lovastatin decreases both VLDL and LDL apo B production in miniature pigs. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 12: 902-10. PMID 1637788 DOI: 10.1161/01.Atv.12.8.902 |
0.42 |
|
| 1992 |
Evans AJ, Sawyez CG, Wolfe BM, Huff MW. Lipolysis is a prerequisite for lipid accumulation in HepG2 cells induced by large hypertriglyceridemic very low density lipoproteins. The Journal of Biological Chemistry. 267: 10743-51. PMID 1587849 |
0.394 |
|
| 1991 |
Huff MW, Evans AJ, Sawyez CG, Wolfe BM, Nestel PJ. Cholesterol accumulation in J774 macrophages induced by triglyceride-rich lipoproteins. Comparison of very low density lipoprotein from subjects with type III, IV, and V hyperlipoproteinemias. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 11: 221-33. PMID 1998641 DOI: 10.1161/01.Atv.11.2.221 |
0.48 |
|
| 1989 |
Khosla P, Samman S, Carroll KK, Huff MW. Turnover of 125I-VLDL and 131I-LDL apolipoprotein B in rabbits fed diets containing casein or soy protein. Biochimica Et Biophysica Acta. 1002: 157-63. PMID 2930765 DOI: 10.1016/0005-2760(89)90282-8 |
0.642 |
|
| 1989 |
Huff MW, Telford DE. Regulation of low density lipoprotein apoprotein B metabolism by lovastatin and cholestyramine in miniature pigs: effects on LDL composition and synthesis of LDL subfractions. Metabolism: Clinical and Experimental. 38: 256-64. PMID 2918845 DOI: 10.1016/0026-0495(89)90084-X |
0.435 |
|
| 1989 |
Huff MW, Telford DE. Dietary fish oil increases conversion of very low density lipoprotein apoprotein B to low density lipoprotein. Arteriosclerosis (Dallas, Tex.). 9: 58-66. PMID 2912422 |
0.315 |
|
| 1989 |
Clark WF, Parbtani A, Huff MW, Reid B, Holub BJ, Falardeau P. Omega-3 fatty acid dietary supplementation in systemic lupus erythematosus. Kidney International. 36: 653-60. PMID 2811063 DOI: 10.1038/Ki.1989.242 |
0.316 |
|
| 1988 |
Huff MW, Breckenridge WC, Strong WL, Wolfe BM. Metabolism of apolipoproteins C-II, C-III, and B in hypertriglyceridemic men. Changes after heparin-induced lipolysis. Arteriosclerosis (Dallas, Tex.). 8: 471-9. PMID 3190554 DOI: 10.1161/01.Atv.8.5.471 |
0.41 |
|
| 1987 |
Hudson AJ, Huff MW, Wright CG, Silver MM, Lo TC, Banerjee D. The role of insulin resistance in the pathogenesis of myotonic muscular dystrophy. Brain : a Journal of Neurology. 110: 469-88. PMID 3552109 DOI: 10.1093/Brain/110.2.469 |
0.361 |
|
| 1985 |
Huff MW, Telford DE. Direct synthesis of low-density lipoprotein apoprotein B in the miniature pig. Metabolism: Clinical and Experimental. 34: 36-42. PMID 3965861 DOI: 10.1016/0026-0495(85)90057-5 |
0.383 |
|
| 1985 |
Huff MW, Telford DE, Woodcroft K, Strong WL. Mevinolin and cholestyramine inhibit the direct synthesis of low density lipoprotein apolipoprotein B in miniature pigs. Journal of Lipid Research. 26: 1175-86. PMID 3906004 |
0.378 |
|
| 1984 |
Huff MW, Giovannetti PM, Wolfe BM. Turnover of very low-density lipoprotein-apoprotein B is increased by substitution of soybean protein for meat and dairy protein in the diets of hypercholesterolemic men American Journal of Clinical Nutrition. 39: 888-897. PMID 6539062 |
0.303 |
|
| 1984 |
Huff MW, Telford DE. Characterization and metabolic fate of two very-low-density lipoprotein subfractions separated by heparin-sepharose chromatography. Biochimica Et Biophysica Acta. 796: 251-61. PMID 6509076 DOI: 10.1016/0005-2760(84)90125-5 |
0.404 |
|
| 1982 |
Huff MW, Roberts DC, Carroll KK. Long-term effects of semipurified diets containing casein or soy protein isolate on atherosclerosis and plasma lipoproteins in rabbits. Atherosclerosis. 41: 327-36. PMID 7199927 DOI: 10.1016/0021-9150(82)90197-6 |
0.641 |
|
| 1982 |
Nestel PJ, Huff MW, Billington T, Fidge NH. Changes in the plasma lipoprotein distribution of apolipoproteins C-II, C-III1, C-III2 and apolipoprotein B after heparin-induced lipolysis. Biochimica Et Biophysica Acta. 712: 94-102. PMID 7115750 DOI: 10.1016/0005-2760(82)90089-3 |
0.356 |
|
| 1982 |
Huff MW, Nestel PJ. Metabolism of apolipoproteins CII, CIII1, CIII2 and VLDL-B in human subjects consuming high carbohydrate diets. Metabolism: Clinical and Experimental. 31: 493-8. PMID 6952065 DOI: 10.1016/0026-0495(82)90240-2 |
0.438 |
|
| 1982 |
Nestel P, Tada N, Billington T, Huff M, Fidge N. Changes in very low density lipoproteins with cholesterol loading in man. Metabolism: Clinical and Experimental. 31: 398-405. PMID 6804752 DOI: 10.1016/0026-0495(82)90117-2 |
0.45 |
|
| 1980 |
Huff MW, Carroll KK. Effects of dietary protein on turnover, oxidation, and absorption of cholesterol, and on steroid excretion in rabbits. Journal of Lipid Research. 21: 546-48. PMID 7400686 |
0.624 |
|
| 1980 |
Huff MW, Carroll KK. Effects of dietary proteins and amino acid mixtures on plasma cholesterol levels in rabbits. The Journal of Nutrition. 110: 1676-85. PMID 7190603 DOI: 10.1093/Jn/110.8.1676 |
0.59 |
|
| 1979 |
Roberts DC, Huff MW, Carroll KK. Influence of diet on plasma cholesterol concentrations in suckling and weanling rabbits. Nutrition and Metabolism. 23: 476-86. PMID 547207 DOI: 10.1159/000176294 |
0.638 |
|
| 1979 |
Roberts DC, Huff MW, Carroll KK. Plasma lipoprotein changes in suckling and weanling rabbits fed semipurified diets. Lipids. 14: 566-71. PMID 222992 DOI: 10.1007/Bf02533533 |
0.653 |
|
| 1979 |
Karlsson I, Marthens Ev, Zamenhof S, Firestone C, Eklund A, Rask L, Loriette C, Pasantes-Morales H, Portemer C, Chatagner F, Roberts DCK, Huff MW, Carroll KK, Whitear SH, Basu TK, et al. Subject Index, Vol. 23, 1979 Annals of Nutrition and Metabolism. 23: 494-496. DOI: 10.1159/000176297 |
0.478 |
|
| 1979 |
Karlsson I, Marthens Ev, Zamenhof S, Firestone C, Eklund A, Rask L, Loriette C, Pasantes-Morales H, Portemer C, Chatagner F, Roberts DCK, Huff MW, Carroll KK, Whitear SH, Basu TK, et al. Contents, Vol. 23, 1979 Annals of Nutrition and Metabolism. 23. DOI: 10.1159/000176288 |
0.52 |
|
| 1978 |
Carroll KK, Hamilton RM, Huff MW, Falconer AD. Dietary fiber and cholesterol metabolism in rabbits and rats. The American Journal of Clinical Nutrition. 31: S203-S207. PMID 707374 DOI: 10.1093/Ajcn/31.10.S203 |
0.629 |
|
| 1978 |
Carroll KK, Giovannetti PM, Huff MW, Moase O, Roberts DC, Wolfe BM. Hypocholesterolemic effect of substituting soybean protein for animal protein in the diet of healthy young women. The American Journal of Clinical Nutrition. 31: 1312-21. PMID 567007 DOI: 10.1093/Ajcn/31.8.1312 |
0.606 |
|
| 1977 |
Carroll KK, Huff MW. Influence of dietary fat and protein on plasma cholesterol levels in the early postnatal period. Advances in Experimental Medicine and Biology. 82: 638-43. PMID 920420 DOI: 10.1007/978-1-4613-4220-5_134 |
0.562 |
|
| 1977 |
Huff MW, Hamilton RM, Carroll KK. Effects of dietary proteins and amino acids on the plasma cholesterol concentrations of rabbits fed cholesterol-free diets. Advances in Experimental Medicine and Biology. 82: 275-7. PMID 920374 DOI: 10.1007/978-1-4613-4220-5_62 |
0.64 |
|
| 1977 |
Huff MW, Hamilton RM, Carroll KK. Plasma cholesterol levels in rabbits fed low fat, cholesterol-free, semipurified diets: effects of dietary proteins, protein hydrolysates and amino acid mixtures. Atherosclerosis. 28: 187-95. PMID 562170 DOI: 10.1016/0021-9150(77)90156-3 |
0.594 |
|
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