| Year |
Citation |
Score |
| 2023 |
Klimtchuk ES, Peterle D, Bullitt EA, Connors LH, Engen JR, Gursky O. Role of Complementarity-Determining Regions 1 and 3 in Pathologic Amyloid Formation by Human Immunoglobulin κ1 Light Chains. Biorxiv : the Preprint Server For Biology. PMID 36778378 DOI: 10.1101/2023.02.01.526662 |
0.365 |
|
| 2022 |
Mendelson L, Sanchorawala V, Connors L, Joshi T, Doros G, Pogrebinsky A, Havasi A. Correlation Between 24-Hour Urine Protein and Random Urine Protein-Creatinine Ratio in Amyloid Light-Chain Amyloidosis. Kidney Medicine. 4: 100427. PMID 35342879 DOI: 10.1016/j.xkme.2022.100427 |
0.312 |
|
| 2021 |
Peterle D, Klimtchuk ES, Wales TE, Georgescauld F, Connors LH, Engen JR, Gursky O. A conservative point mutation in a dynamic antigen-binding loop of human immunoglobulin λ6 light chain promotes pathologic amyloid formation. Journal of Molecular Biology. 167310. PMID 34678302 DOI: 10.1016/j.jmb.2021.167310 |
0.325 |
|
| 2020 |
Torres-Arancivia CM, Chang D, Hackett WE, Zaia J, Connors LH. Glycosylation of Serum Clusterin in Wild-Type Transthyretin-Associated (ATTRwt) Amyloidosis: A Study of Disease-Associated Compositional Features Using Mass Spectrometry Analyses. Biochemistry. PMID 33141553 DOI: 10.1021/acs.biochem.0c00590 |
0.413 |
|
| 2020 |
Giadone RM, Liberti DC, Matte TM, Rosarda JD, Torres-Arancivia C, Ghosh S, Diedrich JK, Pankow S, Skvir N, Jean JC, Yates JR, Wilson AA, Connors LH, Kotton DN, Wiseman RL, et al. Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease. Stem Cell Reports. PMID 32735824 DOI: 10.1016/J.Stemcr.2020.07.003 |
0.409 |
|
| 2020 |
Schulman A, Connors LH, Weinberg J, Mendelson LM, Joshi T, Shelton AC, Sanchorawala V. Patient Outcomes in Light Chain (AL) amyloidosis: the Clock is Ticking from Symptoms to Diagnosis. European Journal of Haematology. PMID 32564450 DOI: 10.1111/Ejh.13472 |
0.302 |
|
| 2020 |
Dasari AKR, Hung I, Michael B, Gan Z, Kelly JW, Connors LH, Griffin RG, Lim KH. Structural Characterization of Cardiac ex vivo Transthyretin Amyloid: Insight into Transthyretin Misfolding Pathway in vivo. Biochemistry. PMID 32338497 DOI: 10.1021/Acs.Biochem.0C00091 |
0.346 |
|
| 2019 |
Fu J, Bhatt N, Kim J, Castrillon J, Carberry P, Molotkov A, Sanchorawala V, Connors L, Lentzsch S, Mintz A. Real-Time PET Imaging with Amyloid Fibril-Reactive Antibody CAEL-101 for Personalized AL Amyloidosis Immunotherapy Clinical Lymphoma Myeloma and Leukemia. 19: e314. DOI: 10.1016/J.Clml.2019.09.516 |
0.31 |
|
| 2018 |
Klimtchuk ES, Prokaeva T, Frame NM, Abdullahi HA, Spencer B, Dasari S, Cui H, Berk JL, Kurtin PJ, Connors LH, Gursky O. Unusual duplication mutation in a surface loop of human transthyretin leads to an aggressive drug-resistant amyloid disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29941560 DOI: 10.1073/Pnas.1802977115 |
0.345 |
|
| 2018 |
Mints YY, Doros G, Berk JL, Connors LH, Ruberg FL. Features of atrial fibrillation in wild-type transthyretin cardiac amyloidosis: a systematic review and clinical experience. Esc Heart Failure. PMID 29916559 DOI: 10.1002/Ehf2.12308 |
0.328 |
|
| 2018 |
Hanson JLS, Arvanitis M, Koch CM, Berk JL, Ruberg FL, Prokaeva T, Connors LH. Use of Serum Transthyretin as a Prognostic Indicator and Predictor of Outcome in Cardiac Amyloid Disease Associated With Wild-Type Transthyretin. Circulation. Heart Failure. 11: e004000. PMID 29449366 DOI: 10.1161/Circheartfailure.117.004000 |
0.356 |
|
| 2018 |
Phull P, Sanchorawala V, Connors LH, Doros G, Ruberg FL, Berk JL, Sarosiek S. Monoclonal gammopathy of undetermined significance in systemic transthyretin amyloidosis (ATTR). Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 1-6. PMID 29424556 DOI: 10.1080/13506129.2018.1436048 |
0.313 |
|
| 2018 |
Staron A, Connors LH, Ruberg FL, Berk JL, Mendelson LM, Sanchorawala V. The Changing Face of Amyloidosis Referrals at a Tertiary Center over the Past 3 Decades Blood. 132: 5536-5536. DOI: 10.1182/Blood-2018-99-112193 |
0.424 |
|
| 2017 |
Lu Y, Jiang Y, Prokaeva T, Connors LH, Costello CE. Oxidative Post-Translational Modifications of an Amyloidogenic Immunoglobulin Light Chain Protein. International Journal of Mass Spectrometry. 416: 71-79. PMID 29358899 DOI: 10.1016/J.Ijms.2016.11.006 |
0.412 |
|
| 2017 |
Chan GG, Koch CM, Connors LH. Serum Proteomic Variability Associated with Clinical Phenotype in Familial Transthyretin Amyloidosis (ATTRm). Journal of Proteome Research. PMID 28922609 DOI: 10.1021/Acs.Jproteome.7B00479 |
0.48 |
|
| 2017 |
Klimtchuk ES, Prokaeva TB, Spencer BH, Gursky O, Connors LH. In vitro co-expression of human amyloidogenic immunoglobulin light and heavy chain proteins: a relevant cell-based model of AL amyloidosis. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 1-8. PMID 28632419 DOI: 10.1080/13506129.2017.1336996 |
0.442 |
|
| 2017 |
Arvanitis M, Simon S, Chan G, Fine D, Beardsley P, LaValley M, Jacobson D, Koch C, Berk JL, Connors LH, Ruberg FL. Retinol binding protein 4 (RBP4) concentration identifies V122I transthyretin cardiac amyloidosis. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 24: 120-121. PMID 28434357 DOI: 10.1080/13506129.2017.1295371 |
0.336 |
|
| 2017 |
Chan GG, Koch CM, Connors LH. Blood proteomic profiling in inherited (ATTRm) and acquired (ATTRwt) forms of transthyretin-associated cardiac amyloidosis. Journal of Proteome Research. PMID 28196416 DOI: 10.1021/Acs.Jproteome.6B00998 |
0.407 |
|
| 2017 |
Arvanitis M, Koch CM, Chan GG, Torres-Arancivia C, LaValley MP, Jacobson DR, Berk JL, Connors LH, Ruberg FL. Identification of Transthyretin Cardiac Amyloidosis Using Serum Retinol-Binding Protein 4 and a Clinical Prediction Model. Jama Cardiology. PMID 28196196 DOI: 10.1001/Jamacardio.2016.5864 |
0.337 |
|
| 2016 |
Prokaeva T, Spencer B, Sun F, O'Hara RM, Seldin DC, Connors LH, Sanchorawala V. Immunoglobulin heavy light chain test quantifies clonal disease in patients with AL amyloidosis and normal serum free light chain ratio. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 1-7. PMID 27677679 DOI: 10.1080/13506129.2016.1219715 |
0.344 |
|
| 2015 |
Connors LH, Sam F, Skinner M, Salinaro F, Sun F, Ruberg FL, Berk JL, Seldin DC. Heart Failure Due to Age-Related Cardiac Amyloid Disease Associated With Wild-Type Transthyretin: A Prospective, Observational Cohort Study. Circulation. PMID 26660282 DOI: 10.1161/Circulationaha.115.018852 |
0.322 |
|
| 2015 |
Sarosiek S, Seldin DC, Connors LH, Spencer B, Murakami A, O'Hara C, Sanchorawala V. Vertebral compression fractures as the initial presentation of AL amyloidosis: case series and review of literature. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 22: 156-62. PMID 26104853 DOI: 10.3109/13506129.2015.1036983 |
0.313 |
|
| 2015 |
Guan J, Mishra S, Qiu Y, Shi J, Trudeau K, Las G, Liesa M, Shirihai OS, Connors LH, Seldin DC, Falk RH, MacRae CA, Liao R. Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity. Embo Molecular Medicine. 7: 688. PMID 25940533 DOI: 10.15252/Emmm.201505318 |
0.436 |
|
| 2015 |
Greene MJ, Klimtchuk ES, Seldin DC, Berk JL, Connors LH. Cooperative stabilization of transthyretin by clusterin and diflunisal. Biochemistry. 54: 268-78. PMID 25478940 DOI: 10.1021/Bi5011249 |
0.505 |
|
| 2015 |
Sikora JL, Logue MW, Chan GG, Spencer BH, Prokaeva TB, Baldwin CT, Seldin DC, Connors LH. Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt). Human Genetics. 134: 111-21. PMID 25367359 DOI: 10.1007/S00439-014-1499-0 |
0.343 |
|
| 2015 |
Prokaeva T, Spencer B, Sun F, McConnell N, O'hara RM, Seldin DC, Connors L, Sanchorawala V. Heavy/Light Chain Quantification Identifies Clonal Plasma Cell Disease in Patients with AL Amyloidosis and Normal Serum Free Light Chain Ratio Blood. 126: 2956-2956. DOI: 10.1182/Blood.V126.23.2956.2956 |
0.364 |
|
| 2015 |
Tahir U, Kim JS, Connors L, Sam F. Clinical Characteristics of Survivors and Non-Survivors with Immunoglobulin Light Chain (AL) Cardiac Amyloid Heart Failure Journal of Cardiac Failure. 21: S90. DOI: 10.1016/J.Cardfail.2015.06.270 |
0.361 |
|
| 2014 |
Guan J, Mishra S, Qiu Y, Shi J, Trudeau K, Las G, Liesa M, Shirihai OS, Connors LH, Seldin DC, Falk RH, MacRae CA, Liao R. Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity. Embo Molecular Medicine. 6: 1493-507. PMID 25319546 DOI: 10.15252/emmm.201404190 |
0.333 |
|
| 2014 |
Phay M, Blinder V, Macy S, Greene MJ, Wooliver DC, Liu W, Planas A, Walsh DM, Connors LH, Primmer SR, Planque SA, Paul S, O'Nuallain B. Transthyretin aggregate-specific antibodies recognize cryptic epitopes on patient-derived amyloid fibrils. Rejuvenation Research. 17: 97-104. PMID 24164623 DOI: 10.1089/Rej.2013.1524 |
0.472 |
|
| 2013 |
Leung A, Nah SK, Reid W, Ebata A, Koch CM, Monti S, Genereux JC, Wiseman RL, Wolozin B, Connors LH, Berk JL, Seldin DC, Mostoslavsky G, Kotton DN, Murphy GJ. Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis. Stem Cell Reports. 1: 451-63. PMID 24286032 DOI: 10.1016/J.Stemcr.2013.10.003 |
0.393 |
|
| 2013 |
Guan J, Mishra S, Shi J, Plovie E, Qiu Y, Cao X, Gianni D, Jiang B, Del Monte F, Connors LH, Seldin DC, Lavatelli F, Rognoni P, Palladini G, Merlini G, et al. Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity. Basic Research in Cardiology. 108: 378. PMID 23982491 DOI: 10.1007/S00395-013-0378-5 |
0.381 |
|
| 2013 |
Mishra S, Guan J, Plovie E, Seldin DC, Connors LH, Merlini G, Falk RH, MacRae CA, Liao R. Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish. American Journal of Physiology. Heart and Circulatory Physiology. 305: H95-103. PMID 23624626 DOI: 10.1152/Ajpheart.00186.2013 |
0.381 |
|
| 2013 |
Tanaka K, Essick EE, Doros G, Tanriverdi K, Connors LH, Seldin DC, Sam F. Circulating matrix metalloproteinases and tissue inhibitors of metalloproteinases in cardiac amyloidosis. Journal of the American Heart Association. 2: e005868. PMID 23537813 DOI: 10.1161/Jaha.112.005868 |
0.412 |
|
| 2012 |
Girnius S, Skinner M, Spencer B, Prokaeva T, Bartholomew C, O'Hara C, Seldin DC, Connors LH. A new lysozyme tyr54asn mutation causing amyloidosis in a family of Swedish ancestry with gastrointestinal symptoms. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 19: 182-5. PMID 22978355 DOI: 10.3109/13506129.2012.723074 |
0.396 |
|
| 2012 |
Kingsbury JS, Laue TM, Chase SF, Connors LH. Detection of high-molecular-weight amyloid serum protein complexes using biological on-line tracer sedimentation. Analytical Biochemistry. 425: 151-6. PMID 22465331 DOI: 10.1016/J.Ab.2012.03.016 |
0.738 |
|
| 2011 |
Ward JE, Ren R, Toraldo G, Soohoo P, Guan J, O'Hara C, Jasuja R, Trinkaus-Randall V, Liao R, Connors LH, Seldin DC. Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis. Blood. 118: 6610-7. PMID 21998211 DOI: 10.1182/Blood-2011-04-351643 |
0.459 |
|
| 2011 |
Connors LH, Doros G, Sam F, Badiee A, Seldin DC, Skinner M. Clinical features and survival in senile systemic amyloidosis: comparison to familial transthyretin cardiomyopathy. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 157-9. PMID 21838471 DOI: 10.3109/13506129.2011.574354059 |
0.34 |
|
| 2011 |
Hovey BM, Ward JE, Soo Hoo P, O'Hara CJ, Connors LH, Seldin DC. Preclinical development of siRNA therapeutics for AL amyloidosis. Gene Therapy. 18: 1150-6. PMID 21562591 DOI: 10.1038/Gt.2011.69 |
0.398 |
|
| 2011 |
Greene MJ, Sam F, Soo Hoo PT, Patel RS, Seldin DC, Connors LH. Evidence for a functional role of the molecular chaperone clusterin in amyloidotic cardiomyopathy. The American Journal of Pathology. 178: 61-8. PMID 21224044 DOI: 10.1016/J.Ajpath.2010.11.015 |
0.494 |
|
| 2010 |
Klimtchuk ES, Gursky O, Patel RS, Laporte KL, Connors LH, Skinner M, Seldin DC. The critical role of the constant region in thermal stability and aggregation of amyloidogenic immunoglobulin light chain. Biochemistry. 49: 9848-57. PMID 20936823 DOI: 10.1021/Bi101351C |
0.317 |
|
| 2010 |
Ren R, Hong Z, Gong H, Laporte K, Skinner M, Seldin DC, Costello CE, Connors LH, Trinkaus-Randall V. Role of glycosaminoglycan sulfation in the formation of immunoglobulin light chain amyloid oligomers and fibrils. The Journal of Biological Chemistry. 285: 37672-82. PMID 20870723 DOI: 10.1074/Jbc.M110.149575 |
0.47 |
|
| 2010 |
Shi J, Guan J, Jiang B, Brenner DA, Del Monte F, Ward JE, Connors LH, Sawyer DB, Semigran MJ, Macgillivray TE, Seldin DC, Falk R, Liao R. Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway. Proceedings of the National Academy of Sciences of the United States of America. 107: 4188-93. PMID 20150510 DOI: 10.1073/Pnas.0912263107 |
0.41 |
|
| 2009 |
Tam M, Seldin DC, Forbes BM, Connors LH, Skinner M, Oran B, Quillen K, Sanchorawala V. Spontaneous rupture of the liver in a patient with systemic AL amyloidosis undergoing treatment with high-dose melphalan and autologous stem cell transplantation: a case report with literature review. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 16: 103-7. PMID 20536404 DOI: 10.1080/13506120902879574 |
0.322 |
|
| 2009 |
Connors LH, Prokaeva T, Lim A, Théberge R, Falk RH, Doros G, Berg A, Costello CE, O'Hara C, Seldin DC, Skinner M. Cardiac amyloidosis in African Americans: comparison of clinical and laboratory features of transthyretin V122I amyloidosis and immunoglobulin light chain amyloidosis. American Heart Journal. 158: 607-14. PMID 19781421 DOI: 10.1016/J.Ahj.2009.08.006 |
0.373 |
|
| 2009 |
Bodi K, Prokaeva T, Spencer B, Eberhard M, Connors LH, Seldin DC. AL-Base: a visual platform analysis tool for the study of amyloidogenic immunoglobulin light chain sequences. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 16: 1-8. PMID 19291508 DOI: 10.1080/13506120802676781 |
0.354 |
|
| 2008 |
Biolo A, Ramamurthy S, Connors LH, O'Hara CJ, Meier-Ewert HK, Soo Hoo PT, Sawyer DB, Seldin DC, Seldin DS, Sam F. Matrix metalloproteinases and their tissue inhibitors in cardiac amyloidosis: relationship to structural, functional myocardial changes and to light chain amyloid deposition. Circulation. Heart Failure. 1: 249-57. PMID 19808299 DOI: 10.1161/Circheartfailure.108.788687 |
0.413 |
|
| 2008 |
Buxbaum J, Koziol J, Connors LH. Serum transthyretin levels in senile systemic amyloidosis: effects of age, gender and ethnicity. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 15: 255-61. PMID 19065297 DOI: 10.1080/13506120802525285 |
0.334 |
|
| 2008 |
Lavatelli F, Perlman DH, Spencer B, Prokaeva T, McComb ME, Théberge R, Connors LH, Bellotti V, Seldin DC, Merlini G, Skinner M, Costello CE. Amyloidogenic and associated proteins in systemic amyloidosis proteome of adipose tissue. Molecular & Cellular Proteomics : McP. 7: 1570-83. PMID 18474516 DOI: 10.1074/Mcp.M700545-Mcp200 |
0.495 |
|
| 2008 |
Kingsbury JS, Laue TM, Klimtchuk ES, Théberge R, Costello CE, Connors LH. The modulation of transthyretin tetramer stability by cysteine 10 adducts and the drug diflunisal. Direct analysis by fluorescence-detected analytical ultracentrifugation. The Journal of Biological Chemistry. 283: 11887-96. PMID 18326041 DOI: 10.1074/Jbc.M709638200 |
0.732 |
|
| 2007 |
Connors LH, Jiang Y, Budnik M, Théberge R, Prokaeva T, Bodi KL, Seldin DC, Costello CE, Skinner M. Heterogeneity in primary structure, post-translational modifications, and germline gene usage of nine full-length amyloidogenic kappa1 immunoglobulin light chains. Biochemistry. 46: 14259-71. PMID 18004879 DOI: 10.1021/Bi7013773 |
0.441 |
|
| 2007 |
Rosenzweig M, Skinner M, Prokaeva T, Théberge R, Costello C, Drachman BM, Connors LH. A new transthyretin variant (Glu61Gly) associated with cardiomyopathy. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 14: 65-71. PMID 17453626 DOI: 10.1080/13506120601116625 |
0.423 |
|
| 2007 |
Kingsbury JS, Klimtchuk ES, Théberge R, Costello CE, Connors LH. Expression, purification, and in vitro cysteine-10 modification of native sequence recombinant human transthyretin. Protein Expression and Purification. 53: 370-7. PMID 17317215 DOI: 10.1016/J.Pep.2007.01.004 |
0.714 |
|
| 2007 |
Kingsbury JS, Théberge R, Karbassi JA, Lim A, Costello CE, Connors LH. Detailed structural analysis of amyloidogenic wild-type transthyretin using a novel purification strategy and mass spectrometry. Analytical Chemistry. 79: 1990-8. PMID 17261023 DOI: 10.1021/Ac061546S |
0.748 |
|
| 2007 |
Kos CA, Ward JE, Malek K, Sanchorawala V, Wright DG, O'Hara C, Connors L, Skinner M, Seldin DC. Association of acquired von Willebrand syndrome with AL amyloidosis. American Journal of Hematology. 82: 363-7. PMID 17205535 DOI: 10.1002/Ajh.20829 |
0.344 |
|
| 2006 |
Monis GF, Schultz C, Ren R, Eberhard J, Costello C, Connors L, Skinner M, Trinkaus-Randall V. Role of endocytic inhibitory drugs on internalization of amyloidogenic light chains by cardiac fibroblasts. The American Journal of Pathology. 169: 1939-52. PMID 17148659 DOI: 10.2353/Ajpath.2006.060183 |
0.335 |
|
| 2005 |
Akar H, Seldin DC, Magnani B, O'Hara C, Berk JL, Schoonmaker C, Cabral H, Dember LM, Sanchorawala V, Connors LH, Falk RH, Skinner M. Quantitative serum free light chain assay in the diagnostic evaluation of AL amyloidosis. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 12: 210-5. PMID 16399645 DOI: 10.1080/13506120500352339 |
0.37 |
|
| 2005 |
Ng B, Connors LH, Davidoff R, Skinner M, Falk RH. Senile systemic amyloidosis presenting with heart failure: a comparison with light chain-associated amyloidosis. Archives of Internal Medicine. 165: 1425-9. PMID 15983293 DOI: 10.1001/Archinte.165.12.1425 |
0.367 |
|
| 2005 |
Chung CM, Chiu JD, Connors LH, Gursky O, Lim A, Dykstra AB, Liepnieks J, Benson MD, Costello CE, Skinner M, Walsh MT. Thermodynamic stability of a kappaI immunoglobulin light chain: relevance to multiple myeloma. Biophysical Journal. 88: 4232-42. PMID 15792972 DOI: 10.1529/Biophysj.105.061317 |
0.342 |
|
| 2005 |
Trinkaus-Randall V, Walsh MT, Steeves S, Monis G, Connors LH, Skinner M. Cellular response of cardiac fibroblasts to amyloidogenic light chains. The American Journal of Pathology. 166: 197-208. PMID 15632012 DOI: 10.1016/S0002-9440(10)62244-4 |
0.33 |
|
| 2005 |
Kos CA, Ward JE, Malek K, Sanchorawala V, Wright DG, O’Hara C, Connors L, Skinner M, Seldin DC. Association of Acquired Von Willebrand Syndrome with Primary (AL) Amyloidosis. Blood. 106: 4078-4078. DOI: 10.1182/Blood.V106.11.4078.4078 |
0.352 |
|
| 2005 |
Ward JE, Brenner D, Cui L, Liao R, Connors LH, Hoo PS, Eberhard J, Christensen T, O’Hara C, Skinner M, Seldin DC. Expression of Human Amyloidogenic Immunoglobulin Light Chains in Mice Leads to Organ Toxicity. Blood. 106: 3412-3412. DOI: 10.1182/Blood.V106.11.3412.3412 |
0.379 |
|
| 2004 |
Connors LH, Yamashita T, Yazaki M, Skinner M, Benson MD. A rare transthyretin mutation (Asp18Glu) associated with cardiomyopathy. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 11: 61-6. PMID 15185501 DOI: 10.1080/13506120410001682569 |
0.372 |
|
| 2004 |
Brenner DA, Jain M, Pimentel DR, Wang B, Connors LH, Skinner M, Apstein CS, Liao R. Human amyloidogenic light chains directly impair cardiomyocyte function through an increase in cellular oxidant stress. Circulation Research. 94: 1008-10. PMID 15044325 DOI: 10.1161/01.Res.0000126569.75419.74 |
0.449 |
|
| 2003 |
Lim A, Prokaeva T, McComb ME, Connors LH, Skinner M, Costello CE. Identification of S-sulfonation and S-thiolation of a novel transthyretin Phe33Cys variant from a patient diagnosed with familial transthyretin amyloidosis. Protein Science : a Publication of the Protein Society. 12: 1775-85. PMID 12876326 DOI: 10.1110/Ps.0349703 |
0.379 |
|
| 2002 |
Yazaki M, Connors LH, Eagle RC, Leff SR, Skinner M, Benson MD. Transthyretin amyloidosis associated with a novel variant (Trp41Leu) presenting with vitreous opacities. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 9: 263-7. PMID 12557756 DOI: 10.3109/13506120209114104 |
0.403 |
|
| 2002 |
Lim A, Prokaeva T, Connors LH, Falk RH, Skinner M, Costello CE. Identification of a novel transthyretin thr59Lys/Arg104His. A case of compound heterozygosity in a Chinese patient diagnosed with familial transthyretin amyloidosis Amyloid. 9: 134-140. PMID 12440486 DOI: 10.3109/13506120208995246 |
0.334 |
|
| 2002 |
Lim A, Prokaeva T, McComb ME, O'Connor PB, Théberge R, Connors LH, Skinner M, Costello CE. Characterization of transthyretin variants in familial transthyretin amyloidosis by mass spectrometric peptide mapping and DNA sequence analysis. Analytical Chemistry. 74: 741-51. PMID 11866053 DOI: 10.1021/Ac010780+ |
0.376 |
|
| 2001 |
Chung CM, Connors LH, Benson MD, Walsh MT. Biophysical analysis of normal transthyretin: implications for fibril formation in senile systemic amyloidosis. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 8: 75-83. PMID 11409037 DOI: 10.3109/13506120109007348 |
0.412 |
|
| 2001 |
Liao R, Jain M, Teller P, Connors LH, Ngoy S, Skinner M, Falk RH, Apstein CS. Infusion of Light Chains From Patients With Cardiac Amyloidosis Causes Diastolic Dysfunction in Isolated Mouse Hearts Circulation. 104: 1594-1597. DOI: 10.1161/Circ.104.14.1594 |
0.416 |
|
| 2000 |
Lim A, Makhov AM, Bond J, Inouye H, Connors LH, Griffith JD, Erickson BW, Kirschner DA, Costello CE. Betabellins 15D and 16D, de Novo designed beta-sandwich proteins that have amyloidogenic properties. Journal of Structural Biology. 130: 363-70. PMID 10940239 DOI: 10.1006/Jsbi.2000.4272 |
0.331 |
|
| 1999 |
Connors LH, Théberge R, Skare J, Costello CE, Falk RH, Skinner M. A new transthyretin variant (Ser23Asn) associated with familial amyloidosis in a Portuguese patient. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 6: 114-8. PMID 10439117 DOI: 10.3109/13506129909007311 |
0.323 |
|
| 1999 |
Wally J, Kica G, Zhang Y, Ericsson T, Connors LH, Benson MD, Liepnieks JJ, Murray J, Skinner M, Comenzo RL. Identification of a novel substitution in the constant region of a gene coding for an amyloidogenic kappa1 light chain. Biochimica Et Biophysica Acta. 1454: 49-56. PMID 10354514 DOI: 10.1016/S0925-4439(99)00019-8 |
0.36 |
|
| 1998 |
Connors LH, Ericsson T, Skare J, Jones LA, Lewis WD, Skinner M. A simple screening test for variant transthyretins associated with familial transthyretin amyloidosis using isoelectric focusing Biochimica Et Biophysica Acta - Molecular Basis of Disease. 1407: 185-192. PMID 9748569 DOI: 10.1016/S0925-4439(98)00037-4 |
0.382 |
|
| 1987 |
Cohen AS, Connors LH. The pathogenesis and biochemistry of amyloidosis. The Journal of Pathology. 151: 1-10. PMID 3559796 DOI: 10.1002/Path.1711510102 |
0.513 |
|
| 1986 |
Skinner M, Stone P, Shirahama T, Connors LH, Calore J, Cohen AS. The association of an elastase with amyloid fibrils. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 181: 211-4. PMID 3633118 DOI: 10.3181/00379727-181-42242 |
0.413 |
|
| 1985 |
Skinner M, Connors LH, Rubinow A, Libbey C, Sipe JD, Cohen AS. Lowered prealbumin levels in patients with familial amyloid polyneuropathy (FAP) and their non-affected but at risk relatives. The American Journal of the Medical Sciences. 289: 17-21. PMID 4038581 DOI: 10.1097/00000441-198501000-00003 |
0.407 |
|
| 1985 |
Gertz MA, Skinner M, Cohen AS, Connors LH, Kyle RA. Isolation and characterization of a kappa amyloid fibril protein. Scandinavian Journal of Immunology. 22: 245-50. PMID 2864740 DOI: 10.1111/J.1365-3083.1985.Tb01877.X |
0.483 |
|
| 1985 |
Connors LH, Shirahama T, Skinner M, Fenves A, Cohen AS. In vitro formation of amyloid fibrils from intact beta 2-microglobulin. Biochemical and Biophysical Research Communications. 131: 1063-8. PMID 2413854 DOI: 10.1016/0006-291X(85)90198-6 |
0.403 |
|
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