Theresa A. Shapiro - Publications

Johns Hopkins University, Baltimore, MD 
Biochemistry, Molecular Biology

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Caton E, Nenortas E, Bakshi RP, Shapiro TA. Kinetic Driver of Antibacterial Drugs Against : Implications for Clinical Dosing. Antimicrobial Agents and Chemotherapy. PMID 31451506 DOI: 10.1128/AAC.00416-19  0.56
2018 Bakshi RP, Tatham LM, Savage AC, Tripathi AK, Mlambo G, Ippolito MM, Nenortas E, Rannard SP, Owen A, Shapiro TA. Long-acting injectable atovaquone nanomedicines for malaria prophylaxis. Nature Communications. 9: 315. PMID 29358624 DOI: 10.1038/s41467-017-02603-z  0.56
2016 Caton E, Nenortas E, Bakshi RP, Shapiro TA. Hollow-Fiber Methodology for Pharmacokinetic/Pharmacodynamic Studies of Antimalarial Compounds. Current Protocols in Chemical Biology. 8: 29-58. PMID 26995353 DOI: 10.1002/9780470559277.ch150194  0.56
2015 Tang Girdwood SC, Nenortas E, Shapiro TA. Targeting the gyrase of Plasmodium falciparum with topoisomerase poisons. Biochemical Pharmacology. 95: 227-37. PMID 25881748 DOI: 10.1016/j.bcp.2015.03.018  0.56
2014 Ettinger DS, Wood DE, Akerley W, Bazhenova LA, Borghaei H, Camidge DR, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Dilling TJ, Govindan R, Grannis FW, Horn L, Jahan TM, ... ... Shapiro TA, et al. Non-small cell lung cancer, version 1.2015. Journal of the National Comprehensive Cancer Network : Jnccn. 12: 1738-61. PMID 25505215  1
2013 Bakshi RP, Nenortas E, Tripathi AK, Sullivan DJ, Shapiro TA. Model system to define pharmacokinetic requirements for antimalarial drug efficacy. Science Translational Medicine. 5: 205ra135. PMID 24089407 DOI: 10.1126/scitranslmed.3006684  1
2013 Grab DJ, Nenortas E, Bakshi RP, Nikolskaia OV, Friedman JE, Shapiro TA. Membrane active chelators as novel anti-African trypanosome and anti-malarial drugs. Parasitology International. 62: 461-3. PMID 23811202 DOI: 10.1016/j.parint.2013.06.009  1
2013 Ettinger DS, Akerley W, Borghaei H, Chang AC, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Govindan R, Grannis FW, Grant SC, Horn L, Jahan TM, Komaki R, Kong FM, ... ... Shapiro TA, et al. Non-small cell lung cancer, version 2.2013. Journal of the National Comprehensive Cancer Network : Jnccn. 11: 645-53; quiz 653. PMID 23744864  1
2013 Ettinger DS, Riely GJ, Akerley W, Borghaei H, Chang AC, Cheney RT, Chirieac LR, D'Amico TA, Demmy TL, Govindan R, Grannis FW, Grant SC, Horn L, Jahan TM, Komaki R, ... ... Shapiro TA, et al. Thymomas and thymic carcinomas: Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network : Jnccn. 11: 562-76. PMID 23667206  1
2012 Fahey JW, Wehage SL, Holtzclaw WD, Kensler TW, Egner PA, Shapiro TA, Talalay P. Protection of humans by plant glucosinolates: Efficiency of conversion of glucosinolates to isothiocyanates by the gastrointestinal microflora Cancer Prevention Research. 5: 603-611. PMID 22318753 DOI: 10.1158/1940-6207.CAPR-11-0538  1
2012 Slack RD, Mott BT, Woodard LE, Tripathi A, Triphati A, Sullivan D, Nenortas E, Girdwood SC, Shapiro TA, Posner GH. Malaria-infected mice are completely cured by one 6 mg/kg oral dose of a new monomeric trioxane sulfide combined with mefloquine. Journal of Medicinal Chemistry. 55: 291-6. PMID 22128829 DOI: 10.1021/jm201214d  1
2009 Woodard LE, Chang W, Chen X, Liu JO, Shapiro TA, Posner GH. Malaria-infected mice live until at least day 30 after a new monomeric trioxane combined with mefloquine are administered together in a single low oral dose Journal of Medicinal Chemistry. 52: 7458-7462. PMID 19586052 DOI: 10.1021/jm9005934  1
2009 Nyunt MM, Hendrix CW, Bakshi RP, Kumar N, Shapiro TA. Phase I/II evaluation of the prophylactic antimalarial activity of pafuramidine in healthy volunteers challenged with Plasmodium falciparum sporozoites. The American Journal of Tropical Medicine and Hygiene. 80: 528-35. PMID 19346370  1
2009 Chen X, Xie S, Bhat S, Kumar N, Shapiro TA, Liu JO. Fumagillin and fumarranol interact with P. falciparum methionine aminopeptidase 2 and inhibit malaria parasite growth in vitro and in vivo. Chemistry & Biology. 16: 193-202. PMID 19246010 DOI: 10.1016/j.chembiol.2009.01.006  1
2009 Rosenthal AS, Chen X, Liu JO, West DC, Hergenrother PJ, Shapiro TA, Posner GH. Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells. Journal of Medicinal Chemistry. 52: 1198-203. PMID 19186946 DOI: 10.1021/jm801484v  1
2009 Bakshi RP, Sang D, Morrell A, Cushman M, Shapiro TA. Activity of indenoisoquinolines against African trypanosomes. Antimicrobial Agents and Chemotherapy. 53: 123-8. PMID 18824603 DOI: 10.1128/AAC.00650-07  1
2008 Posner GH, Chang W, Hess L, Woodard L, Sinishtaj S, Usera AR, Maio W, Rosenthal AS, Kalinda AS, D'Angelo JG, Petersen KS, Stohler R, Chollet J, Santo-Tomas J, Snyder C, ... ... Shapiro TA, et al. Malaria-infected mice are cured by oral administration of new artemisinin derivatives. Journal of Medicinal Chemistry. 51: 1035-42. PMID 18232653 DOI: 10.1021/jm701168h  1
2007 Posner GH, Paik IH, Chang W, Borstnik K, Sinishtaj S, Rosenthal AS, Shapiro TA. Malaria-infected mice are cured by a single dose of novel artemisinin derivatives Journal of Medicinal Chemistry. 50: 2516-2519. PMID 17439113 DOI: 10.1021/jm070149m  1
2007 Dinkova-Kostova AT, Fahey JW, Wade KL, Jenkins SN, Shapiro TA, Fuchs EJ, Kerns ML, Talalay P. Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 847-51. PMID 17416783 DOI: 10.1158/1055-9965.EPI-06-0934  1
2006 Shapiro TA, Fahey JW, Dinkova-Kostova AT, Holtzclaw WD, Stephenson KK, Wade KL, Ye L, Talalay P. Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: A clinical phase I study Nutrition and Cancer. 55: 53-62. PMID 16965241 DOI: 10.1207/s15327914nc5501_7  1
2006 Paik IH, Xie S, Shapiro TA, Labonte T, Narducci Sarjeant AA, Baege AC, Posner GH. Second generation, orally active, antimalarial, artemisinin-derived trioxane dimers with high stability, efficacy, and anticancer activity Journal of Medicinal Chemistry. 49: 2731-2734. PMID 16640333 DOI: 10.1021/jm058288w  1
2006 Kulikowicz T, Shapiro TA. Distinct genes encode type II Topoisomerases for the nucleus and mitochondrion in the protozoan parasite Trypanosoma brucei. The Journal of Biological Chemistry. 281: 3048-56. PMID 16316982 DOI: 10.1074/jbc.M505977200  1
2004 Bakshi RP, Shapiro TA. RNA interference of Trypanosoma brucei topoisomerase IB: both subunits are essential. Molecular and Biochemical Parasitology. 136: 249-55. PMID 15478803 DOI: 10.1016/j.molbiopara.2004.04.006  1
2004 Posner GH, McRiner AJ, Paik IH, Sur S, Borstnik K, Xie S, Shapiro TA, Alagbala A, Foster B. Anticancer and antimalarial efficacy and safety of artemisinin-derived trioxane dimers in rodents. Journal of Medicinal Chemistry. 47: 1299-301. PMID 14971910 DOI: 10.1021/jm0303711  1
2003 Nenortas E, Kulikowicz T, Burri C, Shapiro TA. Antitrypanosomal activities of fluoroquinolones with pyrrolidinyl substitutions. Antimicrobial Agents and Chemotherapy. 47: 3015-7. PMID 12937017  1
2003 Bachi MD, Korshin EE, Hoos R, Szpilman AM, Ploypradith P, Xie S, Shapiro TA, Posner GH. A short synthesis and biological evaluation of potent and nontoxic antimalarial bridged bicyclic beta-sulfonyl-endoperoxides. Journal of Medicinal Chemistry. 46: 2516-33. PMID 12773055 DOI: 10.1021/jm020584a  1
2003 Posner GH, Paik IH, Sur S, McRiner AJ, Borstnik K, Xie S, Shapiro TA. Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy. Journal of Medicinal Chemistry. 46: 1060-5. PMID 12620083 DOI: 10.1021/jm020461q  1
2002 Borstnik K, Paik IH, Shapiro TA, Posner GH. Antimalarial chemotherapeutic peroxides: artemisinin, yingzhaosu A and related compounds. International Journal For Parasitology. 32: 1661-7. PMID 12435451 DOI: 10.1016/S0020-7519(02)00195-9  1
2002 Posner GH, Jeon HB, Ploypradith P, Paik IH, Borstnik K, Xie S, Shapiro TA. Orally active, water-soluble antimalarial 3-aryltrioxanes: short synthesis and preclinical efficacy testing in rodents. Journal of Medicinal Chemistry. 45: 3824-8. PMID 12190305 DOI: 10.1021/jm020210h  1
2002 Ye L, Dinkova-Kostova AT, Wade KL, Zhang Y, Shapiro TA, Talalay P. Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: Pharmacokinetics of broccoli sprout isothiocyanates in humans Clinica Chimica Acta. 316: 43-53. PMID 11750273 DOI: 10.1016/S0009-8981(01)00727-6  1
2002 Posner GH, Northrop J, Paik IH, Borstnik K, Dolan P, Kensler TW, Xie S, Shapiro TA. New chemical and biological aspects of artemisinin-derived trioxane dimers. Bioorganic & Medicinal Chemistry. 10: 227-32. PMID 11738625 DOI: 10.1016/S0968-0896(01)00270-X  1
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