Lily Q. Dong - Publications

The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States 
Pharmacology, Biochemistry, Molecular Biology

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bai J, Cervantes C, He S, He J, Plasko GR, Wen J, Li Z, Yin D, Zhang C, Liu M, Dong LQ, Liu F. Mitochondrial stress-activated cGAS-STING pathway inhibits thermogenic program and contributes to overnutrition-induced obesity in mice. Communications Biology. 3: 257. PMID 32444826 DOI: 10.1038/s42003-020-0986-1  0.36
2019 Ryu J, Loza CA, Xu H, Zhou M, Hadley JT, Wu J, You H, Wang H, Yang J, Bai J, Liu F, Bialowas C, Dong LQ. Potential Roles of Adiponectin Isoforms in Human Obesity with Delayed Wound Healing. Cells. 8. PMID 31554182 DOI: 10.3390/cells8101134  0.36
2019 Yang M, Zhao L, Gao P, Zhu X, Han Y, Chen X, Li L, Xiao Y, Wei L, Li C, Xiao L, Yuan S, Liu F, Dong LQ, Kanwar YS, et al. DsbA-L ameliorates high glucose induced tubular damage through maintaining MAM integrity. Ebiomedicine. PMID 31060900 DOI: 10.1016/j.ebiom.2019.04.044  0.36
2019 Chen X, Han Y, Gao P, Yang M, Xiao L, Xiong X, Zhao H, Tang C, Chen G, Zhu X, Yuan S, Liu F, Dong LQ, Liu F, Kanwar YS, et al. Disulfide-bond A oxidoreductase-like protein protects against ectopic fat deposition and lipid-related kidney damage in diabetic nephropathy. Kidney International. PMID 30791996 DOI: 10.1016/j.kint.2018.10.038  0.36
2018 Galan-Davila AK, Ryu J, Dong K, Xiao Y, Dai Z, Zhang D, Li Z, Dick AM, Liu KD, Kamat A, Lu M, Dong Q, Liu F, Dong LQ. Alternative splicing variant of the scaffold protein APPL1 suppresses hepatic adiponectin signaling and function. The Journal of Biological Chemistry. PMID 29483192 DOI: 10.1074/jbc.RA118.002162  0.36
2017 Bai J, Cervantes C, Liu J, He S, Zhou H, Zhang B, Cai H, Yin D, Hu D, Li Z, Chen H, Gao X, Wang F, O'Connor JC, Xu Y, ... ... Dong LQ, et al. DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 29087318 DOI: 10.1073/pnas.1708744114  0.36
2017 Chen H, Bai J, Dong F, Fang H, Zhang Y, Meng W, Liu B, Luo Y, Liu M, Bai Y, Abdul-Ghani MA, Li R, Wu J, Zeng R, Zhou Z, ... Dong LQ, et al. Erratum. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 31: 4203. PMID 28860308 DOI: 10.1096/fj.201600985RERR  0.36
2017 Chen H, Bai J, Dong F, Fang H, Zhang Y, Meng W, Liu B, Luo Y, Liu M, Bai Y, Abdul-Ghani MA, Li R, Wu J, Zeng R, Zhou Z, ... Dong LQ, et al. Hepatic DsbA-L protects mice from diet-induced hepatosteatosis and insulin resistance. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 28232481 DOI: 10.1096/fj.201600985R  0.36
2016 Ruan H, Dong LQ. Adiponectin signaling and function in insulin target tissues. Journal of Molecular Cell Biology. PMID 26993044 DOI: 10.1093/jmcb/mjw014  0.52
2015 Cai H, Dong LQ, Liu F. Recent Advances in Adipose mTOR Signaling and Function: Therapeutic Prospects. Trends in Pharmacological Sciences. PMID 26700098 DOI: 10.1016/  0.52
2015 Tan Y, Xin X, Coffey FJ, Wiest DL, Dong LQ, Testa JR. Appl1 and Appl2 are Expendable for Mouse Development But Are Essential for HGF-Induced Akt Activation and Migration in Mouse Embryonic Fibroblasts. Journal of Cellular Physiology. PMID 26445298 DOI: 10.1002/jcp.25211  0.52
2015 Liu M, Chen H, Wei L, Hu D, Dong K, Jia W, Dong LQ, Liu F. Endoplasmic reticulum (ER) localization is critical for DsbA-L protein to suppress ER stress and adiponectin down-regulation in adipocytes. The Journal of Biological Chemistry. 290: 10143-8. PMID 25739441 DOI: 10.1074/jbc.M115.645416  0.36
2014 Ryu J, Galan AK, Xin X, Dong F, Abdul-Ghani MA, Zhou L, Wang C, Li C, Holmes BM, Sloane LB, Austad SN, Guo S, Musi N, DeFronzo RA, Deng C, ... ... Dong LQ, et al. APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor. Cell Reports. 7: 1227-38. PMID 24813896 DOI: 10.1016/j.celrep.2014.04.006  0.52
2014 Wu Y, Tu Q, Valverde P, Zhang J, Murray D, Dong LQ, Cheng J, Jiang H, Rios M, Morgan E, Tang Z, Chen J. Central adiponectin administration reveals new regulatory mechanisms of bone metabolism in mice. American Journal of Physiology. Endocrinology and Metabolism. 306: E1418-30. PMID 24780611 DOI: 10.1152/ajpendo.00048.2014  0.52
2014 Liu M, Bai J, He S, Villarreal R, Hu D, Zhang C, Yang X, Liang H, Slaga TJ, Yu Y, Zhou Z, Blenis J, Scherer PE, Dong LQ, Liu F. Grb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1. Cell Metabolism. 19: 967-80. PMID 24746805 DOI: 10.1016/j.cmet.2014.03.018  0.52
2014 Ou X, Liu M, Luo H, Dong LQ, Liu F. Ursolic acid inhibits leucine-stimulated mTORC1 signaling by suppressing mTOR localization to lysosome. Plos One. 9: e95393. PMID 24740400 DOI: 10.1371/journal.pone.0095393  0.36
2013 Piccio L, Cantoni C, Henderson JG, Hawiger D, Ramsbottom M, Mikesell R, Ryu J, Hsieh CS, Cremasco V, Haynes W, Dong LQ, Chan L, Galimberti D, Cross AH. Lack of adiponectin leads to increased lymphocyte activation and increased disease severity in a mouse model of multiple sclerosis. European Journal of Immunology. 43: 2089-100. PMID 23640763 DOI: 10.1002/eji.201242836  0.52
2012 Kikani CK, Verona EV, Ryu J, Shen Y, Ye Q, Zheng L, Qian Z, Sakaue H, Nakamura K, Du J, Ji Q, Ogawa W, Sun LZ, Dong LQ, Liu F. Proliferative and antiapoptotic signaling stimulated by nuclear-localized PDK1 results in oncogenesis. Science Signaling. 5: ra80. PMID 23131847 DOI: 10.1126/scisignal.2003065  0.36
2012 Liu M, Xiang R, Wilk SA, Zhang N, Sloane LB, Azarnoush K, Zhou L, Chen H, Xiang G, Walter CA, Austad SN, Musi N, DeFronzo RA, Asmis R, Scherer PE, ... Dong LQ, et al. Fat-specific DsbA-L overexpression promotes adiponectin multimerization and protects mice from diet-induced obesity and insulin resistance. Diabetes. 61: 2776-86. PMID 22807031 DOI: 10.2337/db12-0169  0.52
2012 Liu M, Zhou L, Wei L, Villarreal R, Yang X, Hu D, Riojas RA, Holmes BM, Langlais PR, Lee H, Dong LQ. Phosphorylation of adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain, and leucine zipper motif 1 (APPL1) at Ser430 mediates endoplasmic reticulum (ER) stress-induced insulin resistance in hepatocytes. The Journal of Biological Chemistry. 287: 26087-93. PMID 22685300 DOI: 10.1074/jbc.M112.372292  0.52
2012 Chocron ES, Sayre NL, Holstein D, Saelim N, Ibdah JA, Dong LQ, Zhu X, Cheng SY, Lechleiter JD. The trifunctional protein mediates thyroid hormone receptor-dependent stimulation of mitochondria metabolism. Molecular Endocrinology (Baltimore, Md.). 26: 1117-28. PMID 22570332 DOI: 10.1210/me.2011-1348  0.52
2011 Deepa SS, Zhou L, Ryu J, Wang C, Mao X, Li C, Zhang N, Musi N, DeFronzo RA, Liu F, Dong LQ. APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCzeta signaling pathway. Molecular Endocrinology (Baltimore, Md.). 25: 1773-85. PMID 21835890 DOI: 10.1210/me.2011-0082  0.52
2011 Holmes RM, Yi Z, De Filippis E, Berria R, Shahani S, Sathyanarayana P, Sherman V, Fujiwara K, Meyer C, Christ-Roberts C, Hwang H, Finlayson J, Dong LQ, Mandarino LJ, Bajaj M. Increased abundance of the adaptor protein containing pleckstrin homology domain, phosphotyrosine binding domain and leucine zipper motif (APPL1) in patients with obesity and type 2 diabetes: evidence for altered adiponectin signalling. Diabetologia. 54: 2122-31. PMID 21562756 DOI: 10.1007/s00125-011-2173-x  0.52
2011 Wang A, Liu M, Liu X, Dong LQ, Glickman RD, Slaga TJ, Zhou Z, Liu F. Up-regulation of adiponectin by resveratrol: the essential roles of the Akt/FOXO1 and AMP-activated protein kinase signaling pathways and DsbA-L. The Journal of Biological Chemistry. 286: 60-6. PMID 20980258 DOI: 10.1074/jbc.M110.188144  0.52
2011 Xin X, Zhou L, Reyes CM, Liu F, Dong LQ. APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway. American Journal of Physiology. Endocrinology and Metabolism. 300: E103-10. PMID 20978232 DOI: 10.1152/ajpendo.00427.2010  0.52
2010 Liu M, Wilk SA, Wang A, Zhou L, Wang RH, Ogawa W, Deng C, Dong LQ, Liu F. Resveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTOR. The Journal of Biological Chemistry. 285: 36387-94. PMID 20851890 DOI: 10.1074/jbc.M110.169284  0.36
2010 Zhou L, Liu M, Zhang J, Chen H, Dong LQ, Liu F. DsbA-L alleviates endoplasmic reticulum stress-induced adiponectin downregulation. Diabetes. 59: 2809-16. PMID 20699416 DOI: 10.2337/db10-0412  0.36
2009 Wang C, Xin X, Xiang R, Ramos FJ, Liu M, Lee HJ, Chen H, Mao X, Kikani CK, Liu F, Dong LQ. Yin-Yang regulation of adiponectin signaling by APPL isoforms in muscle cells. The Journal of Biological Chemistry. 284: 31608-15. PMID 19661063 DOI: 10.1074/jbc.M109.010355  0.52
2009 Zhou L, Zhang J, Fang Q, Liu M, Liu X, Jia W, Dong LQ, Liu F. Autophagy-mediated insulin receptor down-regulation contributes to endoplasmic reticulum stress-induced insulin resistance. Molecular Pharmacology. 76: 596-603. PMID 19541767 DOI: 10.1124/mol.109.057067  0.36
2009 Zhou L, Deepa SS, Etzler JC, Ryu J, Mao X, Fang Q, Liu DD, Torres JM, Jia W, Lechleiter JD, Liu F, Dong LQ. Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent pathways. The Journal of Biological Chemistry. 284: 22426-35. PMID 19520843 DOI: 10.1074/jbc.M109.028357  0.52
2009 Liu X, Liu M, Zhang J, Bai X, Ramos F, Van Remmen H, Richardson A, Liu FY, Dong LQ, Liu F. Downregulation of Grb2 contributes to the insulin-sensitizing effect of calorie restriction. American Journal of Physiology. Endocrinology and Metabolism. 296: E1067-75. PMID 19240254 DOI: 10.1152/ajpendo.90714.2008  0.36
2009 Wang C, Liu M, Riojas RA, Xin X, Gao Z, Zeng R, Wu J, Dong LQ, Liu F. Protein kinase C theta (PKCtheta)-dependent phosphorylation of PDK1 at Ser504 and Ser532 contributes to palmitate-induced insulin resistance. The Journal of Biological Chemistry. 284: 2038-44. PMID 19047061 DOI: 10.1074/jbc.M806336200  0.36
2008 Liu M, Zhou L, Xu A, Lam KS, Wetzel MD, Xiang R, Zhang J, Xin X, Dong LQ, Liu F. A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization. Proceedings of the National Academy of Sciences of the United States of America. 105: 18302-7. PMID 19011089 DOI: 10.1073/pnas.0806341105  0.52
2007 Wang L, Balas B, Christ-Roberts CY, Kim RY, Ramos FJ, Kikani CK, Li C, Deng C, Reyna S, Musi N, Dong LQ, DeFronzo RA, Liu F. Peripheral disruption of the Grb10 gene enhances insulin signaling and sensitivity in vivo. Molecular and Cellular Biology. 27: 6497-505. PMID 17620412 DOI: 10.1128/MCB.00679-07  0.52
2007 Li J, Mao X, Dong LQ, Liu F, Tong L. Crystal structures of the BAR-PH and PTB domains of human APPL1. Structure (London, England : 1993). 15: 525-33. PMID 17502098 DOI: 10.1016/j.str.2007.03.011  0.52
2007 Wang C, Mao X, Wang L, Liu M, Wetzel MD, Guan KL, Dong LQ, Liu F. Adiponectin sensitizes insulin signaling by reducing p70 S6 kinase-mediated serine phosphorylation of IRS-1. The Journal of Biological Chemistry. 282: 7991-6. PMID 17244624 DOI: 10.1074/jbc.M700098200  0.52
2006 Mao X, Hong JY, Dong LQ. The adiponectin signaling pathway as a novel pharmacological target. Mini Reviews in Medicinal Chemistry. 6: 1331-40. PMID 17168809 DOI: 10.2174/138955706778992978  0.52
2006 Riojas RA, Kikani CK, Wang C, Mao X, Zhou L, Langlais PR, Hu D, Roberts JL, Dong LQ, Liu F. Fine tuning PDK1 activity by phosphorylation at Ser163. The Journal of Biological Chemistry. 281: 21588-93. PMID 16751192 DOI: 10.1074/jbc.M600393200  0.52
2006 Mao X, Kikani CK, Riojas RA, Langlais P, Wang L, Ramos FJ, Fang Q, Christ-Roberts CY, Hong JY, Kim RY, Liu F, Dong LQ. APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function. Nature Cell Biology. 8: 516-23. PMID 16622416 DOI: 10.1038/ncb1404  0.52
2006 Ramos FJ, Langlais PR, Hu D, Dong LQ, Liu F. Grb10 mediates insulin-stimulated degradation of the insulin receptor: a mechanism of negative regulation. American Journal of Physiology. Endocrinology and Metabolism. 290: E1262-6. PMID 16434550 DOI: 10.1152/ajpendo.00609.2005  0.36
2005 Kikani CK, Dong LQ, Liu F. "New"-clear functions of PDK1: beyond a master kinase in the cytosol? Journal of Cellular Biochemistry. 96: 1157-62. PMID 16187290 DOI: 10.1002/jcb.20651  0.36
2005 Luo M, Reyna S, Wang L, Yi Z, Carroll C, Dong LQ, Langlais P, Weintraub ST, Mandarino LJ. Identification of insulin receptor substrate 1 serine/threonine phosphorylation sites using mass spectrometry analysis: regulatory role of serine 1223. Endocrinology. 146: 4410-6. PMID 16020478 DOI: 10.1210/en.2005-0260  0.52
2005 Dong LQ, Liu F. PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle. American Journal of Physiology. Endocrinology and Metabolism. 289: E187-96. PMID 16014356 DOI: 10.1152/ajpendo.00011.2005  0.36
2005 Langlais P, Wang C, Dong LQ, Carroll CA, Weintraub ST, Liu F. Phosphorylation of Grb10 by mitogen-activated protein kinase: identification of Ser150 and Ser476 of human Grb10zeta as major phosphorylation sites. Biochemistry. 44: 8890-7. PMID 15952796 DOI: 10.1021/bi050413i  0.52
2004 Lim MA, Yang L, Zheng Y, Wu H, Dong LQ, Liu F. Roles of PDK-1 and PKN in regulating cell migration and cortical actin formation of PTEN-knockout cells. Oncogene. 23: 9348-58. PMID 15531926 DOI: 10.1038/sj.onc.1208147  0.52
2004 Langlais P, Dong LQ, Ramos FJ, Hu D, Li Y, Quon MJ, Liu F. Negative regulation of insulin-stimulated mitogen-activated protein kinase signaling by Grb10. Molecular Endocrinology (Baltimore, Md.). 18: 350-8. PMID 14615605 DOI: 10.1210/me.2003-0117  0.36
2003 Lim MA, Kikani CK, Wick MJ, Dong LQ. Nuclear translocation of 3'-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function. Proceedings of the National Academy of Sciences of the United States of America. 100: 14006-11. PMID 14623982 DOI: 10.1073/pnas.2335486100  0.52
2003 Wick MJ, Ramos FJ, Chen H, Quon MJ, Dong LQ, Liu F. Mouse 3-phosphoinositide-dependent protein kinase-1 undergoes dimerization and trans-phosphorylation in the activation loop. The Journal of Biological Chemistry. 278: 42913-9. PMID 12923190 DOI: 10.1074/jbc.M304172200  0.36
2003 Wick KR, Werner ED, Langlais P, Ramos FJ, Dong LQ, Shoelson SE, Liu F. Grb10 inhibits insulin-stimulated insulin receptor substrate (IRS)-phosphatidylinositol 3-kinase/Akt signaling pathway by disrupting the association of IRS-1/IRS-2 with the insulin receptor. The Journal of Biological Chemistry. 278: 8460-7. PMID 12493740 DOI: 10.1074/jbc.M208518200  0.52
2002 Dong LQ, Ramos FJ, Wick MJ, Lim MA, Guo Z, Strong R, Richardson A, Liu F. Cloning and characterization of a testis and brain-specific isoform of mouse 3'-phosphoinositide-dependent protein kinase-1, mPDK-1 beta. Biochemical and Biophysical Research Communications. 294: 136-44. PMID 12054753 DOI: 10.1016/S0006-291X(02)00449-7  0.52
2002 Wick MJ, Wick KR, Chen H, He H, Dong LQ, Quon MJ, Liu F. Substitution of the autophosphorylation site Thr516 with a negatively charged residue confers constitutive activity to mouse 3-phosphoinositide-dependent protein kinase-1 in cells. The Journal of Biological Chemistry. 277: 16632-8. PMID 11877406 DOI: 10.1074/jbc.M112402200  0.52
1997 Dong LQ, Farris S, Christal J, Liu F. Site-directed mutagenesis and yeast two-hybrid studies of the insulin and insulin-like growth factor-1 receptors: the Src homology-2 domain-containing protein hGrb10 binds to the autophosphorylated tyrosine residues in the kinase domain of the insulin receptor. Molecular Endocrinology (Baltimore, Md.). 11: 1757-65. PMID 9369444 DOI: 10.1210/mend.11.12.0014  0.36
1997 Dong LQ, Du H, Porter SG, Kolakowski LF, Lee AV, Mandarino J, Fan J, Yee D, Liu F. Cloning, chromosome localization, expression, and characterization of an Src homology 2 and pleckstrin homology domain-containing insulin receptor binding protein hGrb10γ Journal of Biological Chemistry. 272: 29104-29112. PMID 9360986 DOI: 10.1074/jbc.272.46.29104  0.52
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