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Linda M. Columbus - Publications

Affiliations: 
Chemistry University of Virginia, Charlottesville, VA 
Area:
magnetic resonance, membrane proteins
Website:
http://www.columbuslabs.org/

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Shu XH, Ruddiman CA, Keller TS, Keller AS, Yang Y, Good ME, Best AK, Columbus L, Isakson BE. Heterocellular Contact Can Dictate Arterial Function. Circulation Research. PMID 30900949 DOI: 10.1161/Circresaha.118.313926  0.36
2019 Kuhn JP, Smirnov A, Criss A, Columbus L. Quantifying CEACAM Targeted Liposome Delivery Using Imaging Flow Cytometry Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.544  0.4
2019 Lake K, Swope N, Columbus L. Investigating the Catalytic Base Residues in the Phosphoglucose Isomerase From Thermotoga maritima Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.398  0.4
2019 Swope N, Columbus L. Impact of Lipid-Protein Interactions on Alpha-Helical Membrane Protein Fold Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.2020  0.4
2019 Martin JN, Criss AK, Columbus L. Molecular Determinants of Neisserial Opa Protein Interactions with Human CEACAMs Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.1888  0.4
2018 Yang J, Zong Y, Su J, Li H, Zhu H, Columbus L, Zhou L, Liu Q. A Novel Conformation of the Polypeptide-Binding Pocket Supports an Active Substrate Release from Hsp70S Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.3019  0.4
2018 Columbus L. Differences Between Micelles, Bicelles, and Membranes and the Impact on Membrane Protein Structure Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.079  0.4
2017 Martin J, Kieber M, Columbus L. Investigation of Affinities and Structures of Membrane Protein-Protein Interactions using Comparable Samples Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.1931  0.4
2016 Keller TC, Butcher JT, Broseghini-Filho GB, Marziano C, DeLalio LJ, Rogers S, Ning B, Martin JN, Chechova S, Cabot M, Shu X, Best AK, Good ME, Simão Padilha A, Purdy M, ... ... Columbus L, et al. Modulating Vascular Hemodynamics With an Alpha Globin Mimetic Peptide (HbαX). Hypertension (Dallas, Tex. : 1979). PMID 27802421 DOI: 10.1161/Hypertensionaha.116.08171  0.36
2016 Martin JN, Ball LM, Solomon TL, Dewald AH, Criss AK, Columbus L. Neisserial Opa protein - CEACAM interactions: competition for receptors as a means for bacterial invasion and pathogenesis. Biochemistry. PMID 27442026 DOI: 10.1021/Acs.Biochem.6B00124  0.48
2016 Kuhn J, Smirnov A, Criss AK, Columbus L. Targeting Liposomes for Uptake into CEACAM-Expressing Human Cells using a Bacterial Membrane Protein Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.3165  0.4
2015 Shu X, Keller TC, Begandt D, Butcher JT, Biwer L, Keller AS, Columbus L, Isakson BE. Endothelial nitric oxide synthase in the microcirculation. Cellular and Molecular Life Sciences : Cmls. 72: 4561-75. PMID 26390975 DOI: 10.1007/S00018-015-2021-0  0.8
2015 Gray C, Price CW, Lee CT, Dewald AH, Cline MA, McAnany CE, Columbus L, Mura C. Known structure, unknown function: An inquiry-based undergraduate biochemistry laboratory course. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. PMID 26148241 DOI: 10.1002/Bmb.20873  0.8
2015 Columbus L. Post-expression strategies for structural investigations of membrane proteins. Current Opinion in Structural Biology. 32: 131-138. PMID 25951412 DOI: 10.1016/J.Sbi.2015.04.005  0.8
2015 Columbus L, Kroncke B. Solution NMR Structure Determination of Polytopic α-Helical Membrane Proteins: A Guide to Spin Label Paramagnetic Relaxation Enhancement Restraints. Methods in Enzymology. 557: 329-48. PMID 25950972 DOI: 10.1016/Bs.Mie.2014.12.005  0.8
2015 Johnson MB, Ball LM, Daily KP, Martin JN, Columbus L, Criss AK. Opa+ Neisseria gonorrhoeae exhibits reduced survival in human neutrophils via Src family kinase-mediated bacterial trafficking into mature phagolysosomes. Cellular Microbiology. 17: 648-65. PMID 25346239 DOI: 10.1111/Cmi.12389  0.8
2015 Kieber MK, Solomon T, Columbus L. Neisserial Opa Protein Dynamics and Interaction with Host Ceacam Receptors Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.531  0.4
2015 Martin JN, Lo RH, Criss AK, Columbus L. Insights into the Specificity of Neisserial Opa Protein Interactions with Human Receptors Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.1114  0.44
2014 Oliver RC, Lipfert J, Fox DA, Lo RH, Kim JJ, Doniach S, Columbus L. Tuning micelle dimensions and properties with binary surfactant mixtures. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 13353-61. PMID 25312254 DOI: 10.1021/La503458N  0.8
2014 Lo RH, Kroncke BM, Solomon TL, Columbus L. Mapping membrane protein backbone dynamics: a comparison of site-directed spin labeling with NMR 15N-relaxation measurements. Biophysical Journal. 107: 1697-702. PMID 25296323 DOI: 10.1016/J.Bpj.2014.08.018  0.8
2014 Straub AC, Butcher JT, Billaud M, Mutchler SM, Artamonov MV, Nguyen AT, Johnson T, Best AK, Miller MP, Palmer LA, Columbus L, Somlyo AV, Le TH, Isakson BE. Hemoglobin α/eNOS coupling at myoendothelial junctions is required for nitric oxide scavenging during vasoconstriction. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 2594-600. PMID 25278292 DOI: 10.1016/J.Niox.2014.09.126  0.8
2014 Butcher JT, Johnson T, Beers J, Columbus L, Isakson BE. Hemoglobin α in the blood vessel wall. Free Radical Biology & Medicine. 73: 136-42. PMID 24832680 DOI: 10.1016/J.Freeradbiomed.2014.04.019  0.8
2014 Fox DA, Larsson P, Lo RH, Kroncke BM, Kasson PM, Columbus L. Structure of the Neisserial outer membrane protein Opa₆₀: loop flexibility essential to receptor recognition and bacterial engulfment. Journal of the American Chemical Society. 136: 9938-46. PMID 24813921 DOI: 10.1021/Ja503093Y  0.8
2014 Kenwood BM, Weaver JL, Bajwa A, Poon IK, Byrne FL, Murrow BA, Calderone JA, Huang L, Divakaruni AS, Tomsig JL, Okabe K, Lo RH, Cameron Coleman G, Columbus L, Yan Z, et al. Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane. Molecular Metabolism. 3: 114-23. PMID 24634817 DOI: 10.1016/J.Molmet.2013.11.005  0.8
2014 Columbus L. Five Strategies for Improving Aerospace Supply Chain Quality Management and Performance Sae International Journal of Aerospace. 7: 142-145. DOI: 10.4271/2014-01-2231  0.36
2014 Columbus L, Fox D, Larsson P, Lo R, Kroncke B, Kasson P. Solution Structure Of Opa60 From N. Gonorrhoeae Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Maf/Pdb  0.4
2014 Baker LA, Chakraverty D, Columbus L, Feig AL, Jenks WS, Pilarz M, Stains M, Waterman R, Wesemann JL. Cottrell Scholars Collaborative New Faculty Workshop: Professional development for new chemistry faculty and initial assessment of its efficacy Journal of Chemical Education. 91: 1874-1881. DOI: 10.1021/Ed500547N  0.8
2013 Li J, Liu Q, Xiao L, Haverstick DM, Dewald A, Columbus L, Kelly K, Landers JP. Label-free method for cell counting in crude biological samples via paramagnetic bead aggregation. Analytical Chemistry. 85: 11233-9. PMID 24187938 DOI: 10.1021/Ac401402H  0.8
2013 Anton BP, Chang YC, Brown P, Choi HP, Faller LL, Guleria J, Hu Z, Klitgord N, Levy-Moonshine A, Maksad A, Mazumdar V, McGettrick M, Osmani L, Pokrzywa R, Rachlin J, ... ... Columbus L, et al. The COMBREX project: design, methodology, and initial results. Plos Biology. 11: e1001638. PMID 24013487 DOI: 10.1371/Journal.Pbio.1001638  0.8
2013 Fox DA, Columbus L. Solution NMR resonance assignment strategies for β-barrel membrane proteins. Protein Science : a Publication of the Protein Society. 22: 1133-40. PMID 23754333 DOI: 10.1002/Pro.2291  0.8
2013 Oliver RC, Lipfert J, Fox DA, Lo RH, Doniach S, Columbus L. Dependence of micelle size and shape on detergent alkyl chain length and head group. Plos One. 8: e62488. PMID 23667481 DOI: 10.1371/Journal.Pone.0062488  0.8
2013 Elkin SR, Kumar A, Price CW, Columbus L. A broad specificity nucleoside kinase from Thermoplasma acidophilum. Proteins. 81: 568-82. PMID 23161756 DOI: 10.1002/Prot.24212  0.8
2013 Kroncke BM, Columbus L. Backbone ¹H, ¹³C and ¹⁵N resonance assignments of the α-helical membrane protein TM0026 from Thermotoga maritima. Biomolecular Nmr Assignments. 7: 203-6. PMID 23011877 DOI: 10.1007/S12104-012-9410-1  0.8
2012 Straub AC, Lohman AW, Billaud M, Johnstone SR, Dwyer ST, Lee MY, Bortz PS, Best AK, Columbus L, Gaston B, Isakson BE. Endothelial cell expression of haemoglobin α regulates nitric oxide signalling. Nature. 491: 473-7. PMID 23123858 DOI: 10.1038/Nature11626  0.8
2012 Johnstone SR, Kroncke BM, Straub AC, Best AK, Dunn CA, Mitchell LA, Peskova Y, Nakamoto RK, Koval M, Lo CW, Lampe PD, Columbus L, Isakson BE. MAPK phosphorylation of connexin 43 promotes binding of cyclin E and smooth muscle cell proliferation. Circulation Research. 111: 201-11. PMID 22652908 DOI: 10.1161/Circresaha.112.272302  0.8
2012 Kroncke BM, Columbus L. Identification and removal of nitroxide spin label contaminant: impact on PRE studies of α-helical membrane proteins in detergent. Protein Science : a Publication of the Protein Society. 21: 589-95. PMID 22389096 DOI: 10.1002/Pro.2038  0.8
2011 Dewald AH, Hodges JC, Columbus L. Physical determinants of β-barrel membrane protein folding in lipid vesicles. Biophysical Journal. 100: 2131-40. PMID 21539780 DOI: 10.1016/J.Bpj.2011.03.025  0.8
2011 Hodges JC, Dewald AH, Columbus L. The Characterization of the Binding of Opacity-Associated Proteins to Human Host Cell Receptors Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.3186  0.48
2010 Kroncke BM, Horanyi PS, Columbus L. Structural origins of nitroxide side chain dynamics on membrane protein α-helical sites. Biochemistry. 49: 10045-60. PMID 20964375 DOI: 10.1021/Bi101148W  0.8
2010 Beuck C, Szymczyna BR, Kerkow DE, Carmel AB, Columbus L, Stanfield RL, Williamson JR. Structure of the GLD-1 homodimerization domain: insights into STAR protein-mediated translational regulation. Structure (London, England : 1993). 18: 377-89. PMID 20223220 DOI: 10.1016/J.Str.2009.12.016  0.8
2010 Dewald AH, Hodges JC, Columbus L. The Spontaneous Refolding of Opacity-Associated Proteins into Lipid Membranes Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.3417  0.48
2009 Columbus L, Lipfert J, Jambunathan K, Fox DA, Sim AY, Doniach S, Lesley SA. Mixing and matching detergents for membrane protein NMR structure determination. Journal of the American Chemical Society. 131: 7320-6. PMID 19425578 DOI: 10.1021/Ja808776J  0.8
2009 Reyes C, Fox DA, Jambunathan K, Nguyen T, Bielnicka I, Columbus L. Molecular Determinants of Neisserial Pathogenesis: Mapping the Interaction Between Opa I and a Human Binding Partner CEACAM1 Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.3819  0.4
2008 McCleverty CJ, Columbus L, Kreusch A, Lesley SA. Structure and ligand binding of the soluble domain of a Thermotoga maritima membrane protein of unknown function TM1634. Protein Science : a Publication of the Protein Society. 17: 869-77. PMID 18369189 DOI: 10.1110/Ps.083432208  0.8
2008 Columbus L. Get focused Engineering and Technology. 3: 68. DOI: 10.1049/et:20080526  0.56
2007 Lipfert J, Columbus L, Chu VB, Lesley SA, Doniach S. Size and shape of detergent micelles determined by small-angle X-ray scattering. The Journal of Physical Chemistry. B. 111: 12427-38. PMID 17924686 DOI: 10.1021/Jp073016L  0.8
2007 Lipfert J, Columbus L, Chu VB, Doniach S. Analysis of small-angle X-ray scattering data of protein-detergent complexes by singular value decomposition Journal of Applied Crystallography. 40: s235-s239. DOI: 10.1107/S0021889807005791  0.8
2006 Columbus L, Lipfert J, Klock H, Millett I, Doniach S, Lesley SA. Expression, purification, and characterization of Thermotoga maritima membrane proteins for structure determination. Protein Science : a Publication of the Protein Society. 15: 961-75. PMID 16597824 DOI: 10.1110/Ps.051874706  0.8
2005 Columbus L, Peti W, Etezady-Esfarjani T, Herrmann T, Wüthrich K. NMR structure determination of the conserved hypothetical protein TM1816 from Thermotoga maritima. Proteins. 60: 552-7. PMID 15937903 DOI: 10.1002/Prot.20465  0.8
2005 Columbus L. Avoiding the pitfalls of channel management Manufacturing Engineer. 84: 16-19. DOI: 10.1049/me:20050602  0.48
2005 Columbus L. The goal of synchronised demand Manufacturing Engineer. 84: 32-35. DOI: 10.1049/me:20050405  0.44
2005 Columbus L. The revolution your customers want Manufacturing Engineer. 84: 26-29. DOI: 10.1049/me:20050304  0.48
2004 Columbus L, Hubbell WL. Mapping backbone dynamics in solution with site-directed spin labeling: GCN4-58 bZip free and bound to DNA. Biochemistry. 43: 7273-87. PMID 15182173 DOI: 10.1021/Bi0497906  0.8
2004 Liang Z, Lou Y, Freed JH, Columbus L, Hubbell WL. A multifrequency electron spin resonance study of T4 lysozyme dynamics using the slowly relaxing local Structure model Journal of Physical Chemistry B. 108: 17649-17659. DOI: 10.1021/Jp0484837  0.8
2002 Columbus L, Hubbell WL. A new spin on protein dynamics. Trends in Biochemical Sciences. 27: 288-95. PMID 12069788 DOI: 10.1016/S0968-0004(02)02095-9  0.8
2001 Columbus L, Kálai T, Jekö J, Hideg K, Hubbell WL. Molecular motion of spin labeled side chains in alpha-helices: analysis by variation of side chain structure. Biochemistry. 40: 3828-46. PMID 11300763 DOI: 10.1021/Bi002645H  0.8
2000 Gaponenko V, Howarth JW, Columbus L, Gasmi-Seabrook G, Yuan J, Hubbell WL, Rosevear PR. Protein global fold determination using site-directed spin and isotope labeling. Protein Science : a Publication of the Protein Society. 9: 302-9. PMID 10716182 DOI: 10.1110/Ps.9.2.302  0.8
1999 Gross A, Columbus L, Hideg K, Altenbach C, Hubbell WL. Structure of the KcsA potassium channel from Streptomyces lividans: a site-directed spin labeling study of the second transmembrane segment. Biochemistry. 38: 10324-35. PMID 10441126 DOI: 10.1021/Bi990856K  0.8
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