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David S. Cafiso, Ph.D. - Publications

Chemistry University of Virginia, Charlottesville, VA 
magnetic resonance, membrane proteins

155 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Nyenhuis SB, Karandikar N, Kiessling V, Kreutzberger AJB, Thapa A, Liang B, Tamm LK, Cafiso DS. Conserved arginine residues in synaptotagmin 1 regulate fusion pore expansion through membrane contact. Nature Communications. 12: 761. PMID 33536412 DOI: 10.1038/s41467-021-21090-x  0.76
2020 Nyenhuis DA, Nilaweera TD, Cafiso DS. Native Cell Environment Constrains Loop Structure in the Escherichia coli Cobalamin Transporter BtuB. Biophysical Journal. 119: 1550-1557. PMID 32946767 DOI: 10.1016/J.Bpj.2020.08.034  0.36
2020 Nyenhuis DA, Nilaweera TD, Niblo JK, Nguyen NQ, DuBay KH, Cafiso DS. Evidence for the Supramolecular Organization of a Bacterial Outer-Membrane Protein from In-Vivo Pulse EPR Spectroscopy. Journal of the American Chemical Society. PMID 32452197 DOI: 10.1021/Jacs.0C01754  0.36
2020 Katti S, Nyenhuis SB, Her B, Cafiso DS, Igumenova TI. Partial Metal Ion Saturation of C2 Domains Primes Synaptotagmin 1-Membrane Interactions. Biophysical Journal. PMID 32075747 DOI: 10.1016/J.Bpj.2020.01.032  0.48
2019 Nilaweera TD, Nyenhuis DA, Nakamoto RK, Cafiso DS. Disulfide Chaperone Knockouts Enable In Vivo Double Spin Labeling of an Outer Membrane Transporter. Biophysical Journal. PMID 31582182 DOI: 10.1016/J.Bpj.2019.09.002  0.36
2019 Nyenhuis SB, Thapa A, Cafiso DS. Phosphatidylinositol 4,5 Bisphosphate Controls the cis and trans Interactions of Synaptotagmin 1. Biophysical Journal. PMID 31301806 DOI: 10.1016/J.Bpj.2019.06.016  0.48
2019 Hays JM, Cafiso DS, Kasson PM. Hybrid Refinement of Heterogeneous Conformational Ensembles Using Spectroscopic Data. The Journal of Physical Chemistry Letters. 3410-3414. PMID 31181934 DOI: 10.1021/Acs.Jpclett.9B01407  0.44
2019 Stevens M, Franke B, Skorupka KA, Cafiso DS, Pornillos O, Mayans O, Norman DG. Exploration of the TRIM Fold of MuRF1 Using EPR Reveals a Canonical Antiparallel Structure and Extended COS-Box. Journal of Molecular Biology. PMID 31125568 DOI: 10.1016/J.Jmb.2019.05.025  0.6
2018 Kiessling V, Kreutzberger AJB, Liang B, Nyenhuis SB, Seelheim P, Castle JD, Cafiso DS, Tamm LK. A molecular mechanism for calcium-mediated synaptotagmin-triggered exocytosis. Nature Structural & Molecular Biology. 25: 911-917. PMID 30291360 DOI: 10.1038/S41594-018-0130-9  0.76
2018 Nyenhuis SB, Cafiso DS. Choice of Reconstitution Protocol Modulates the Aggregation state of Full-Length Membrane-Reconstituted Synaptotagmin-1. Protein Science : a Publication of the Protein Society. PMID 29500903 DOI: 10.1002/Pro.3398  0.48
2018 Sarver J, Zhang M, Liu L, Nyenhuis D, Cafiso DS. A Dynamic Protein-Protein Coupling Between the TonB-dependent Transporter FhuA and TonB. Biochemistry. PMID 29338257 DOI: 10.1021/Acs.Biochem.7B01223  0.36
2017 Roganowicz MD, Komurlu S, Mukherjee S, Plewka J, Alam SL, Skorupka KA, Wan Y, Dawidowski D, Cafiso DS, Ganser-Pornillos BK, Campbell EM, Pornillos O. TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition. Plos Pathogens. 13: e1006686. PMID 29040325 DOI: 10.1371/Journal.Ppat.1006686  1
2017 Lee J, Nyenhuis DA, Nelson EA, Cafiso DS, White JM, Tamm LK. Structure of the Ebola virus envelope protein MPER/TM domain and its interaction with the fusion loop explains their fusion activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28874543 DOI: 10.1073/Pnas.1708052114  0.76
2017 Katti S, Nyenhuis SB, Her B, Srivastava AK, Taylor AB, Hart PJ, Cafiso DS, Igumenova TI. Non-native metal ion reveals the role of electrostatics in Synaptotagmin 1-membrane interactions. Biochemistry. PMID 28574251 DOI: 10.1021/Acs.Biochem.7B00188  0.48
2017 Zdanowicz R, Kreutzberger A, Liang B, Kiessling V, Tamm LK, Cafiso DS. Complexin Binding to Membranes and Acceptor t-SNAREs Explains Its Clamping Effect on Fusion. Biophysical Journal. PMID 28456331 DOI: 10.1016/J.Bpj.2017.04.002  0.76
2017 Perez-Lara A, Thapa A, Nyenhuis SB, Nyenhuis DA, Halder P, Tietzel M, Tittmann K, Cafiso DS, Jahn R. Cooperation of PtdInsP2 and PtdSer in synaptotagmin-1 membrane binding. Febs Journal. 199-199. DOI: 10.1111/Febs.14167  0.48
2016 Pérez-Lara Á, Thapa A, Nyenhuis SB, Nyenhuis DA, Halder P, Tietzel M, Tittmann K, Cafiso DS, Jahn R. PtdInsP2 and PtdSer cooperate to trap synaptotagmin-1 to the plasma membrane in the presence of calcium. Elife. 5. PMID 27791979 DOI: 10.7554/Elife.15886  0.48
2016 Dawidowski D, Cafiso DS. Munc18-1 and the Syntaxin-1 N Terminus Regulate Open-Closed States in a t-SNARE Complex. Structure (London, England : 1993). PMID 26876096 DOI: 10.1016/J.Str.2016.01.005  1
2016 Joseph B, Sikora A, Cafiso DS. Ligand induced conformational changes of a membrane transporter in E. coli cells observed with DEER/PELDOR. Journal of the American Chemical Society. PMID 26795032 DOI: 10.1021/Jacs.5B13382  1
2016 Pérez-Lara Á, Thapa A, Nyenhuis SB, Nyenhuis DA, Halder P, Tietzel M, Tittmann K, Cafiso DS, Jahn R. Author response: PtdInsP2 and PtdSer cooperate to trap synaptotagmin-1 to the plasma membrane in the presence of calcium Elife. DOI: 10.7554/Elife.15886.018  0.48
2015 Park Y, Seo JB, Fraind A, Pérez-Lara A, Yavuz H, Han K, Jung SR, Kattan I, Walla PJ, Choi M, Cafiso DS, Koh DS, Jahn R. Synaptotagmin-1 binds to PIP2-containing membrane but not to SNAREs at physiological ionic strength. Nature Structural & Molecular Biology. PMID 26389740 DOI: 10.1038/Nsmb.3097  1
2015 Joseph B, Sikora A, Bordignon E, Jeschke G, Cafiso DS, Prisner TF. Distance Measurement on an Endogenous Membrane Transporter in E. coli Cells and Native Membranes Using EPR Spectroscopy. Angewandte Chemie (International Ed. in English). 54: 6196-9. PMID 25826642 DOI: 10.1002/Anie.201501086  1
2014 Iyalomhe O, Herrick DZ, Cafiso DS, Maloney PC. Closure of the cytoplasmic gate formed by TM5 and TM11 during transport in the oxalate/formate exchanger from Oxalobacter formigenes. Biochemistry. 53: 7735-44. PMID 25409483 DOI: 10.1021/Bi5012173  1
2014 Cafiso DS. Identifying and quantitating conformational exchange in membrane proteins using site-directed spin labeling. Accounts of Chemical Research. 47: 3102-9. PMID 25152957 DOI: 10.1021/Ar500228S  1
2014 Lu B, Kiessling V, Tamm LK, Cafiso DS. The juxtamembrane linker of full-length synaptotagmin 1 controls oligomerization and calcium-dependent membrane binding. The Journal of Biological Chemistry. 289: 22161-71. PMID 24973220 DOI: 10.1074/Jbc.M114.569327  1
2014 Liang B, Dawidowski D, Ellena JF, Tamm LK, Cafiso DS. The SNARE motif of synaptobrevin exhibits an aqueous-interfacial partitioning that is modulated by membrane curvature. Biochemistry. 53: 1485-94. PMID 24552121 DOI: 10.1021/Bi401638U  1
2013 Regan MC, Horanyi PS, Pryor EE, Sarver JL, Cafiso DS, Bushweller JH. Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited. Proceedings of the National Academy of Sciences of the United States of America. 110: 13374-9. PMID 23898196 DOI: 10.1073/Pnas.1301726110  1
2013 Dawidowski D, Cafiso DS. Allosteric control of syntaxin 1a by Munc18-1: characterization of the open and closed conformations of syntaxin. Biophysical Journal. 104: 1585-94. PMID 23561535 DOI: 10.1016/J.Bpj.2013.02.004  1
2013 Freed DM, Lukasik SM, Sikora A, Mokdad A, Cafiso DS. Monomeric TonB and the Ton box are required for the formation of a high-affinity transporter-TonB complex. Biochemistry. 52: 2638-48. PMID 23517233 DOI: 10.1021/Bi3016108  1
2012 Cafiso DS. Taking the pulse of protein interactions by EPR spectroscopy. Biophysical Journal. 103: 2047-8. PMID 23200037 DOI: 10.1016/J.Bpj.2012.10.005  1
2012 Mokdad A, Herrick DZ, Kahn AK, Andrews E, Kim M, Cafiso DS. Ligand-induced structural changes in the Escherichia coli ferric citrate transporter reveal modes for regulating protein-protein interactions. Journal of Molecular Biology. 423: 818-30. PMID 22982293 DOI: 10.1016/J.Jmb.2012.09.003  1
2012 Boura E, Różycki B, Chung HS, Herrick DZ, Canagarajah B, Cafiso DS, Eaton WA, Hummer G, Hurley JH. Solution structure of the ESCRT-I and -II supercomplex: implications for membrane budding and scission. Structure (London, England : 1993). 20: 874-86. PMID 22579254 DOI: 10.1016/J.Str.2012.03.008  1
2012 Flores Jiménez RH, Cafiso DS. The N-terminal domain of a TonB-dependent transporter undergoes a reversible stepwise denaturation. Biochemistry. 51: 3642-50. PMID 22497281 DOI: 10.1021/Bi300118A  1
2011 Jiménez RH, Freed DM, Cafiso DS. Lipid and membrane mimetic environments modulate spin label side chain configuration in the outer membrane protein A. The Journal of Physical Chemistry. B. 115: 14822-30. PMID 22034842 DOI: 10.1021/Jp207420D  1
2011 Freed DM, Khan AK, Horanyi PS, Cafiso DS. Molecular origin of electron paramagnetic resonance line shapes on β-barrel membrane proteins: the local solvation environment modulates spin-label configuration. Biochemistry. 50: 8792-803. PMID 21894979 DOI: 10.1021/Bi200971X  1
2011 Lai AL, Tamm LK, Ellena JF, Cafiso DS. Synaptotagmin 1 modulates lipid acyl chain order in lipid bilayers by demixing phosphatidylserine. The Journal of Biological Chemistry. 286: 25291-300. PMID 21610074 DOI: 10.1074/Jbc.M111.258848  1
2011 Boura E, Rózycki B, Herrick DZ, Chung HS, Vecer J, Eaton WA, Cafiso DS, Hummer G, Hurley JH. Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 108: 9437-42. PMID 21596998 DOI: 10.1073/Pnas.1101763108  1
2011 Ellena JF, Lackowicz P, Mongomery H, Cafiso DS. Membrane thickness varies around the circumference of the transmembrane protein BtuB. Biophysical Journal. 100: 1280-7. PMID 21354401 DOI: 10.1016/J.Bpj.2011.01.055  1
2011 Kuo W, Herrick DZ, Cafiso DS. Phosphatidylinositol 4,5-bisphosphate alters synaptotagmin 1 membrane docking and drives opposing bilayers closer together. Biochemistry. 50: 2633-41. PMID 21344950 DOI: 10.1021/Bi200049C  1
2011 Wan C, Kiessling V, Cafiso DS, Tamm LK. Partitioning of synaptotagmin I C2 domains between liquid-ordered and liquid-disordered inner leaflet lipid phases. Biochemistry. 50: 2478-85. PMID 21322640 DOI: 10.1021/Bi101864K  1
2011 Lai AL, Huang H, Herrick DZ, Epp N, Cafiso DS. Synaptotagmin 1 and SNAREs form a complex that is structurally heterogeneous. Journal of Molecular Biology. 405: 696-706. PMID 21087613 DOI: 10.1016/J.Jmb.2010.11.015  1
2010 Freed DM, Horanyi PS, Wiener MC, Cafiso DS. Conformational exchange in a membrane transport protein is altered in protein crystals. Biophysical Journal. 99: 1604-10. PMID 20816073 DOI: 10.1016/J.Bpj.2010.06.026  1
2010 Flores Jiménez RH, Do Cao MA, Kim M, Cafiso DS. Osmolytes modulate conformational exchange in solvent-exposed regions of membrane proteins. Protein Science : a Publication of the Protein Society. 19: 269-78. PMID 20014029 DOI: 10.1002/Pro.305  1
2009 Ellena JF, Liang B, Wiktor M, Stein A, Cafiso DS, Jahn R, Tamm LK. Dynamic structure of lipid-bound synaptobrevin suggests a nucleation-propagation mechanism for trans-SNARE complex formation. Proceedings of the National Academy of Sciences of the United States of America. 106: 20306-11. PMID 19918058 DOI: 10.1073/Pnas.0908317106  1
2009 Herrick DZ, Kuo W, Huang H, Schwieters CD, Ellena JF, Cafiso DS. Solution and membrane-bound conformations of the tandem C2A and C2B domains of synaptotagmin 1: Evidence for bilayer bridging. Journal of Molecular Biology. 390: 913-23. PMID 19501597 DOI: 10.1016/J.Jmb.2009.06.007  1
2009 Do Cao MA, Crouzy S, Kim M, Becchi M, Cafiso DS, Di Pietro A, Jault JM. Probing the conformation of the resting state of a bacterial multidrug ABC transporter, BmrA, by a site-directed spin labeling approach. Protein Science : a Publication of the Protein Society. 18: 1507-20. PMID 19479721 DOI: 10.1002/Pro.141  1
2009 Kuo W, Herrick DZ, Ellena JF, Cafiso DS. The calcium-dependent and calcium-independent membrane binding of synaptotagmin 1: two modes of C2B binding. Journal of Molecular Biology. 387: 284-94. PMID 19302798 DOI: 10.1016/J.Jmb.2009.01.064  1
2009 Ellena J, Liang B, Wiktor M, Stein A, Cafiso D, Jahn R, Tamm L. NMR chemical shifts of soluble synaptobrevin (1-96) in buffer and in DPC micelle Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr16514  0.52
2008 Huang H, Cafiso DS. Conformation and membrane position of the region linking the two C2 domains in synaptotagmin 1 by site-directed spin labeling. Biochemistry. 47: 12380-8. PMID 18956883 DOI: 10.1021/Bi801470M  1
2008 Zhou Y, Cierpicki T, Jimenez RH, Lukasik SM, Ellena JF, Cafiso DS, Kadokura H, Beckwith J, Bushweller JH. NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation. Molecular Cell. 31: 896-908. PMID 18922471 DOI: 10.1016/J.Molcel.2008.08.028  1
2008 Bhowmik A, Ellena JF, Bryant RG, Cafiso DS. Spin-diffusion couples proton relaxation rates for proteins in exchange with a membrane interface. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 194: 283-8. PMID 18723378 DOI: 10.1016/J.Jmr.2008.07.023  1
2008 Xu Q, Kim M, Ho KW, Lachowicz P, Fanucci GE, Cafiso DS. Membrane hydrocarbon thickness modulates the dynamics of a membrane transport protein. Biophysical Journal. 95: 2849-58. PMID 18586842 DOI: 10.1529/Biophysj.108.133629  1
2008 Dicko A, Frazier AA, Liboiron BD, Hinderliter A, Ellena JF, Xie X, Cho C, Weber T, Tardi PG, Cabral-Lilly D, Cafiso DS, Mayer LD. Intra and inter-molecular interactions dictate the aggregation state of irinotecan co-encapsulated with floxuridine inside liposomes. Pharmaceutical Research. 25: 1702-13. PMID 18320294 DOI: 10.1007/S11095-008-9561-Z  1
2008 Kim M, Xu Q, Murray D, Cafiso DS. Solutes alter the conformation of the ligand binding loops in outer membrane transporters. Biochemistry. 47: 670-9. PMID 18092811 DOI: 10.1021/Bi7016415  1
2008 Zhou Y, Cierpicki T, Jimenez RHF, Lukasik SM, Ellena JF, Cafiso DS, Kadokura H, Beckwith J, Bushweller JH. Solution NMR structure of integral membrane protein DsbB Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2K73/Pdb  0.84
2007 Derewenda U, Tarricone C, Choi WC, Cooper DR, Lukasik S, Perrina F, Tripathy A, Kim MH, Cafiso DS, Musacchio A, Derewenda ZS. The structure of the coiled-coil domain of Ndel1 and the basis of its interaction with Lis1, the causal protein of Miller-Dieker lissencephaly. Structure (London, England : 1993). 15: 1467-81. PMID 17997972 DOI: 10.1016/J.Str.2007.09.015  1
2007 Liao H, Ellena J, Liu L, Szabo G, Cafiso D, Castle D. Secretory carrier membrane protein SCAMP2 and phosphatidylinositol 4,5-bisphosphate interactions in the regulation of dense core vesicle exocytosis. Biochemistry. 46: 10909-20. PMID 17713930 DOI: 10.1021/Bi701121J  1
2007 Kim M, Fanucci GE, Cafiso DS. Substrate-dependent transmembrane signaling in TonB-dependent transporters is not conserved. Proceedings of the National Academy of Sciences of the United States of America. 104: 11975-80. PMID 17606918 DOI: 10.1073/Pnas.0702172104  1
2007 Lukasik SM, Ho KW, Cafiso DS. Molecular basis for substrate-dependent transmembrane signaling in an outer-membrane transporter. Journal of Molecular Biology. 370: 807-11. PMID 17555764 DOI: 10.1016/J.Jmb.2007.05.040  1
2006 Xu Q, Ellena JF, Kim M, Cafiso DS. Substrate-dependent unfolding of the energy coupling motif of a membrane transport protein determined by double electron-electron resonance. Biochemistry. 45: 10847-54. PMID 16953570 DOI: 10.1021/Bi061051X  1
2006 Fanucci GE, Cafiso DS. Recent advances and applications of site-directed spin labeling. Current Opinion in Structural Biology. 16: 644-53. PMID 16949813 DOI: 10.1016/J.Sbi.2006.08.008  1
2006 Herrick DZ, Sterbling S, Rasch KA, Hinderliter A, Cafiso DS. Position of synaptotagmin I at the membrane interface: cooperative interactions of tandem C2 domains. Biochemistry. 45: 9668-74. PMID 16893168 DOI: 10.1021/Bi060874J  1
2006 Kim M, Xu Q, Fanucci GE, Cafiso DS. Solutes modify a conformational transition in a membrane transport protein. Biophysical Journal. 90: 2922-9. PMID 16443663 DOI: 10.1529/Biophysj.105.078246  1
2006 Cafiso DS. Structure and Interactions of C2 Domains at Membrane Surfaces Protein-Lipid Interactions: From Membrane Domains to Cellular Networks. 403-422. DOI: 10.1002/3527606769.ch16  1
2005 Li Y, Han X, Lai AL, Bushweller JH, Cafiso DS, Tamm LK. Membrane structures of the hemifusion-inducing fusion peptide mutant G1S and the fusion-blocking mutant G1V of influenza virus hemagglutinin suggest a mechanism for pore opening in membrane fusion. Journal of Virology. 79: 12065-76. PMID 16140782 DOI: 10.1128/Jvi.79.18.12065-12076.2005  1
2005 Rufener E, Frazier AA, Wieser CM, Hinderliter A, Cafiso DS. Membrane-bound orientation and position of the synaptotagmin C2B domain determined by site-directed spin labeling. Biochemistry. 44: 18-28. PMID 15628842 DOI: 10.1021/Bi048370D  1
2004 Ellena JF, Moulthrop J, Wu J, Rauch M, Jaysinghne S, Castle JD, Cafiso DS. Membrane position of a basic aromatic peptide that sequesters phosphatidylinositol 4,5 bisphosphate determined by site-directed spin labeling and high-resolution NMR. Biophysical Journal. 87: 3221-33. PMID 15315949 DOI: 10.1529/Biophysj.104.046748  1
2004 Gambhir A, Hangyás-Mihályné G, Zaitseva I, Cafiso DS, Wang J, Murray D, Pentyala SN, Smith SO, McLaughlin S. Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins. Biophysical Journal. 86: 2188-207. PMID 15041659 DOI: 10.1016/S0006-3495(04)74278-2  1
2003 Fanucci GE, Lee JY, Cafiso DS. Membrane mimetic environments alter the conformation of the outer membrane protein BtuB. Journal of the American Chemical Society. 125: 13932-3. PMID 14611209 DOI: 10.1021/Ja0376442  1
2003 Fanucci GE, Lee JY, Cafiso DS. Spectroscopic evidence that osmolytes used in crystallization buffers inhibit a conformation change in a membrane protein. Biochemistry. 42: 13106-12. PMID 14609320 DOI: 10.1021/Bi035439T  1
2003 Ellena JF, Burnitz MC, Cafiso DS. Location of the myristoylated alanine-rich C-kinase substrate (MARCKS) effector domain in negatively charged phospholipid bicelles. Biophysical Journal. 85: 2442-8. PMID 14507707 DOI: 10.1016/S0006-3495(03)74667-0  1
2003 Fanucci GE, Cadieux N, Kadner RJ, Cafiso DS. Competing ligands stabilize alternate conformations of the energy coupling motif of a TonB-dependent outer membrane transporter. Proceedings of the National Academy of Sciences of the United States of America. 100: 11382-7. PMID 13679579 DOI: 10.1073/Pnas.1932486100  1
2003 Cadieux N, Phan PG, Cafiso DS, Kadner RJ. Differential substrate-induced signaling through the TonB-dependent transporter BtuB. Proceedings of the National Academy of Sciences of the United States of America. 100: 10688-93. PMID 12958215 DOI: 10.1073/Pnas.1932538100  1
2003 Choudhury-Mukherjee I, Schenck HA, Cechova S, Pajewski TN, Kapur J, Ellena J, Cafiso DS, Brown ML. Design, synthesis, and evaluation of analogues of 3,3,3-trifluoro-2-hydroxy-2-phenyl-propionamide as orally available general anesthetics. Journal of Medicinal Chemistry. 46: 2494-501. PMID 12773053 DOI: 10.1021/Jm020546R  1
2003 Fanucci GE, Coggshall KA, Cadieux N, Kim M, Kadner RJ, Cafiso DS. Substrate-induced conformational changes of the periplasmic N-terminus of an outer-membrane transporter by site-directed spin labeling. Biochemistry. 42: 1391-400. PMID 12578351 DOI: 10.1021/Bi027120Z  1
2003 Frazier AA, Roller CR, Havelka JJ, Hinderliter A, Cafiso DS. Membrane-bound orientation and position of the synaptotagmin I C2A domain by site-directed spin labeling. Biochemistry. 42: 96-105. PMID 12515543 DOI: 10.1021/Bi0268145  1
2002 Ellena JF, Obraztsov VV, Cumbea VL, Woods CM, Cafiso DS. Perfluorooctyl bromide has limited membrane solubility and is located at the bilayer center. Locating small molecules in lipid bilayers through paramagnetic enhancements of NMR relaxation. Journal of Medicinal Chemistry. 45: 5534-42. PMID 12459021 DOI: 10.1021/Jm020278X  1
2002 Fanucci GE, Cadieux N, Piedmont CA, Kadner RJ, Cafiso DS. Structure and dynamics of the beta-barrel of the membrane transporter BtuB by site-directed spin labeling. Biochemistry. 41: 11543-51. PMID 12269798 DOI: 10.1021/Bi0259397  1
2002 Guo Z, Liu L, Cafiso D, Castle D. Perturbation of a very late step of regulated exocytosis by a secretory carrier membrane protein (SCAMP2)-derived peptide Journal of Biological Chemistry. 277: 35357-35363. PMID 12124380 DOI: 10.1074/Jbc.M202259200  1
2002 Frazier AA, Wisner MA, Malmberg NJ, Victor KG, Fanucci GE, Nalefski EA, Falke JJ, Cafiso DS. Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling. Biochemistry. 41: 6282-92. PMID 12009889 DOI: 10.1021/Bi0160821  0.92
2002 Rauch ME, Ferguson CG, Prestwich GD, Cafiso DS. Myristoylated alanine-rich C kinase substrate (MARCKS) sequesters spin-labeled phosphatidylinositol 4,5-bisphosphate in lipid bilayers. The Journal of Biological Chemistry. 277: 14068-76. PMID 11825894 DOI: 10.1074/Jbc.M109572200  1
2002 Cafiso DS. Peptide-membrane interactions determined using site-directed spin labeling Current Topics in Membranes. 52: 3-29. DOI: 10.1016/S1063-5823(02)52003-2  1
2001 Coggshall KA, Cadieux N, Piedmont C, Kadner RJ, Cafiso DS. Transport-defective mutations alter the conformation of the energy-coupling motif of an outer membrane transporter. Biochemistry. 40: 13964-71. PMID 11705387 DOI: 10.1021/Bi015602P  1
2001 Victor KG, Cafiso DS. Location and dynamics of basic peptides at the membrane interface: electron paramagnetic resonance spectroscopy of tetramethyl-piperidine-N-oxyl-4-amino-4-carboxylic acid-labeled peptides. Biophysical Journal. 81: 2241-50. PMID 11566794 DOI: 10.1016/S0006-3495(01)75871-7  1
2001 Han X, Bushweller JH, Cafiso DS, Tamm LK. Membrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutinin. Nature Structural Biology. 8: 715-20. PMID 11473264 DOI: 10.1038/90434  1
2000 Hubbard C, Singleton D, Rauch M, Jayasinghe S, Cafiso D, Castle D. The secretory carrier membrane protein family: Structure and membrane topology Molecular Biology of the Cell. 11: 2933-2947. PMID 10982391 DOI: 10.1091/Mbc.11.9.2933  1
2000 Hubbell WL, Cafiso DS, Altenbach C. Identifying conformational changes with site-directed spin labeling. Nature Structural Biology. 7: 735-9. PMID 10966640 DOI: 10.1038/78956  1
2000 Merianos HJ, Cadieux N, Lin CH, Kadner RJ, Cafiso DS. Substrate-induced exposure of an energy-coupling motif of a membrane transporter. Nature Structural Biology. 7: 205-9. PMID 10700278 DOI: 10.1038/73309  1
2000 Kessel A, Cafiso DS, Ben-Tal N. Continuum solvent model calculations of alamethicin-membrane interactions: thermodynamic aspects. Biophysical Journal. 78: 571-83. PMID 10653772 DOI: 10.1042/Bst028A147  1
1999 Gorzelle BM, Nagy JK, Oxenoid K, Lonzer WL, Cafiso DS, Sanders CR. Reconstitutive refolding of diacylglycerol kinase, an integral membrane protein. Biochemistry. 38: 16373-82. PMID 10587463 DOI: 10.1021/Bi991292N  1
1999 Victor K, Jacob J, Cafiso DS. Interactions controlling the membrane binding of basic protein domains: phenylalanine and the attachment of the myristoylated alanine-rich C-kinase substrate protein to interfaces. Biochemistry. 38: 12527-36. PMID 10504221 DOI: 10.1021/Bi990847B  1
1999 Jacob J, Baker B, Bryant RG, Cafiso DS. Distance estimates from paramagnetic enhancements of nuclear relaxation in linear and flexible model peptides. Biophysical Journal. 77: 1086-92. PMID 10423452 DOI: 10.1016/S0006-3495(99)76958-4  1
1999 Lewis JR, Cafiso DS. Correlation between the free energy of a channel-forming voltage-gated peptide and the spontaneous curvature of bilayer lipids. Biochemistry. 38: 5932-8. PMID 10231547 DOI: 10.1021/Bi9828167  1
1999 Jacob J, Duclohier H, Cafiso DS. The role of proline and glycine in determining the backbone flexibility of a channel-forming peptide. Biophysical Journal. 76: 1367-76. PMID 10049319 DOI: 10.1016/S0006-3495(99)77298-X  1
1999 Ellena JF, Le M, Cafiso DS, Solis RM, Langston M, Sankaram MB. Distribution of phospholipids and triglycerides in multivesicular lipid particles Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents. 6: 97-106. DOI: 10.1080/107175499267011  1
1999 Cafiso DS. Chapter 7 Interaction of Natural and Model Peptides with Membranes Current Topics in Membranes and Transport. 48: 197-228. DOI: 10.1016/S0070-2161(08)61045-X  1
1998 Cafiso DS. Dipole potentials and spontaneous curvature: membrane properties that could mediate anesthesia. Toxicology Letters. 100: 431-9. PMID 10049176 DOI: 10.1016/S0378-4274(98)00217-3  1
1998 Jayasinghe S, Barranger-Mathys M, Ellena JF, Franklin C, Cafiso DS. Structural features that modulate the transmembrane migration of a hydrophobic peptide in lipid vesicles. Biophysical Journal. 74: 3023-30. PMID 9635757 DOI: 10.1016/S0006-3495(98)78010-5  1
1998 Victor K, Cafiso DS. Structure and position of the N-terminal membrane-binding domain of pp60src at the membrane interface. Biochemistry. 37: 3402-10. PMID 9521661 DOI: 10.1021/Bi9721501  1
1998 Vinton BB, Wertz SL, Jacob J, Steere J, Grisham CM, Cafiso DS, Sando JJ. Influence of lipid on the structure and phosphorylation of protein kinase C alpha substrate peptides. The Biochemical Journal. 330: 1433-42. PMID 9494117  1
1997 Hodges MW, Cafiso DS, Polnaszek CF, Lester CC, Bryant RG. Water translational motion at the bilayer interface: an NMR relaxation dispersion measurement. Biophysical Journal. 73: 2575-9. PMID 9370451 DOI: 10.1016/S0006-3495(97)78286-9  1
1997 Addona GH, Andrews SH, Cafiso DS. Estimating the electrostatic potential at the acetylcholine receptor agonist site using power saturation EPR. Biochimica Et Biophysica Acta. 1329: 74-84. PMID 9370246 DOI: 10.1016/S0005-2736(97)00089-8  1
1997 Arbuzova A, Wang J, Murray D, Jacob J, Cafiso DS, McLaughlin S. Kinetics of interaction of the myristoylated alanine-rich C kinase substrate, membranes, and calmodulin. The Journal of Biological Chemistry. 272: 27167-77. PMID 9341159 DOI: 10.1074/Jbc.272.43.27167  1
1997 North C, Cafiso DS. Contrasting membrane localization and behavior of halogenated cyclobutanes that follow or violate the Meyer-Overton hypothesis of general anesthetic potency. Biophysical Journal. 72: 1754-61. PMID 9083679 DOI: 10.1016/S0006-3495(97)78821-0  1
1996 Qin Z, Wertz SL, Jacob J, Savino Y, Cafiso DS. Defining protein-protein interactions using site-directed spin-labeling: the binding of protein kinase C substrates to calmodulin. Biochemistry. 35: 13272-6. PMID 8873591 DOI: 10.1021/Bi961747Y  1
1996 Wertz SL, Savino Y, Cafiso DS. Solution and membrane bound structure of a peptide derived from the protein kinase C substrate domain of neuromodulin. Biochemistry. 35: 11104-12. PMID 8780514 DOI: 10.1021/Bi961248X  1
1996 Qin Z, Cafiso DS. Membrane structure of protein kinase C and calmodulin binding domain of myristoylated alanine rich C kinase substrate determined by site-directed spin labeling. Biochemistry. 35: 2917-25. PMID 8608129 DOI: 10.1021/Bi9521452  1
1996 Barranger-Mathys M, Cafiso DS. Membrane structure of voltage-gated channel forming peptides by site-directed spin-labeling. Biochemistry. 35: 498-505. PMID 8555220 DOI: 10.1021/Bi951985D  1
1995 North CL, Barranger-Mathys M, Cafiso DS. Membrane orientation of the N-terminal segment of alamethicin determined by solid-state 15N NMR. Biophysical Journal. 69: 2392-7. PMID 8599645 DOI: 10.1016/S0006-3495(95)80108-6  1
1995 Baber J, Ellena JF, Cafiso DS. Distribution of general anesthetics in phospholipid bilayers determined using 2H NMR and 1H-1H NOE spectroscopy. Biochemistry. 34: 6533-9. PMID 7756284 DOI: 10.1021/Bi00019A035  1
1995 Qin Z, Szabo G, Cafiso DS. Anesthetics reduce the magnitude of the membrane dipole potential. Measurements in lipid vesicles using voltage-sensitive spin probes. Biochemistry. 34: 5536-43. PMID 7727414 DOI: 10.1021/Bi00016A027  1
1995 Ferguson PJ, Martin EN, Greene KL, Kuhn S, Cafiso DS, Addona G, Taylor RP. Antigen-based heteropolymers facilitate, via primate erythrocyte complement receptor type 1, rapid erythrocyte binding of an autoantibody and its clearance from the circulation in rhesus monkeys. Journal of Immunology (Baltimore, Md. : 1950). 155: 339-47. PMID 7602110  1
1994 Barranger-Mathys M, Cafiso DS. Collisions between helical peptides in membranes monitored using electron paramagnetic resonance: evidence that alamethicin is monomeric in the absence of a membrane potential. Biophysical Journal. 67: 172-6. PMID 7918984 DOI: 10.1016/S0006-3495(94)80466-7  1
1994 North CL, Franklin JC, Bryant RG, Cafiso DS. Molecular flexibility demonstrated by paramagnetic enhancements of nuclear relaxation. Application to alamethicin: a voltage-gated peptide channel. Biophysical Journal. 67: 1861-6. PMID 7532020 DOI: 10.1016/S0006-3495(94)80667-8  1
1994 Cafiso DS. Alamethicin: a peptide model for voltage gating and protein-membrane interactions. Annual Review of Biophysics and Biomolecular Structure. 23: 141-65. PMID 7522664 DOI: 10.1146/Annurev.Bb.23.060194.001041  1
1994 Franklin JC, Ellena JF, Jayasinghe S, Kelsh LP, Cafiso DS. Structure of micelle-associated alamethicin from 1H NMR. Evidence for conformational heterogeneity in a voltage-gated peptide. Biochemistry. 33: 4036-45. PMID 7511413 DOI: 10.1021/Bi00179A032  1
1993 Franklin JC, Cafiso DS. Internal electrostatic potentials in bilayers: measuring and controlling dipole potentials in lipid vesicles. Biophysical Journal. 65: 289-99. PMID 8396456 DOI: 10.1016/S0006-3495(93)81051-8  1
1993 Franklin JC, Cafiso DS, Flewelling RF, Hubbell WL. Probes of membrane electrostatics: synthesis and voltage-dependent partitioning of negative hydrophobic ion spin labels in lipid vesicles. Biophysical Journal. 64: 642-53. PMID 8386011 DOI: 10.1016/S0006-3495(93)81423-1  1
1993 Ellena JF, Lepore LS, Cafiso DS. Estimating lipid lateral diffusion in phospholipid vesicles from carbon-13 spin-spin relaxation The Journal of Physical Chemistry. 97: 2952-2957. DOI: 10.1021/J100114A021  0.84
1993 Ellena JF, Lepore LS, Cafiso DS. Estimating lipid lateral diffusion in phospholipid vesicles from 13C spin-spin relaxation Journal of Physical Chemistry. 97: 2952-2957.  1
1992 Kelsh LP, Ellena JF, Cafiso DS. Determination of the molecular dynamics of alamethicin using 13C NMR: implications for the mechanism of gating of a voltage-dependent channel. Biochemistry. 31: 5136-44. PMID 1606136 DOI: 10.1021/Bi00137A007  1
1992 Lepore LS, Ellena JF, Cafiso DS. Comparison of the lipid acyl chain dynamics between small and large unilamellar vesicles. Biophysical Journal. 61: 767-75. PMID 1504247 DOI: 10.1016/S0006-3495(92)81881-7  1
1991 Archer SJ, Ellena JF, Cafiso DS. Dynamics and aggregation of the peptide ion channel alamethicin. Measurements using spin-labeled peptides. Biophysical Journal. 60: 389-98. PMID 1717016 DOI: 10.1016/S0006-3495(91)82064-1  1
1991 Archer SJ, Cafiso DS. Voltage-dependent conductance for alamethicin in phospholipid vesicles. A test for the mechanism of gating. Biophysical Journal. 60: 380-8. PMID 1717015 DOI: 10.1016/S0006-3495(91)82063-X  1
1991 Cafiso DS. Lipid bilayers: membrane-protein electrostatic interactions. Current Opinion in Structural Biology 1991, 1:185-190 Current Opinion in Structural Biology. 1: 185-190. DOI: 10.1016/0959-440X(91)90059-3  1
1989 Moore CR, Yates JR, Griffin PR, Shabanowitz J, Martino PA, Hunt DF, Cafiso DS. Proteolytic fragments of the nicotinic acetylcholine receptor identified by mass spectrometry: implications for receptor topography. Biochemistry. 28: 9184-91. PMID 2605252 DOI: 10.1021/Bi00449A034  1
1989 Cafiso D, McLaughlin A, McLaughlin S, Winiski A. Measuring electrostatic potentials adjacent to membranes Methods in Enzymology. 171: 342-364. PMID 2593846 DOI: 10.1016/S0076-6879(89)71019-3  1
1989 Cafiso DS. Electron paramagnetic resonance methods for measuring pH gradients, transmembrane potentials, and membrane dynamics. Methods in Enzymology. 172: 331-45. PMID 2546014 DOI: 10.1016/S0076-6879(89)72022-X  1
1989 Raines DE, Cafiso DS. The enhancement of proton/hydroxyl flow across lipid vesicles by inhalation anesthetics. Anesthesiology. 70: 57-63. PMID 2536253 DOI: 10.1097/00000542-198901000-00013  1
1988 Hartsel SC, Perkins WR, McGarvey GJ, Cafiso DS. A selective cholesterol-dependent induction of H+/OH- currents in phospholipid vesicles by amphotericin B. Biochemistry. 27: 2656-60. PMID 2840944 DOI: 10.1021/Bi00408A004  1
1988 Ellena JF, Archer SJ, Dominey RN, Hill BD, Cafiso DS. Localizing the nitroxide group of fatty acid and voltage-sensitive spin-labels in phospholipid bilayers. Biochimica Et Biophysica Acta. 940: 63-70. PMID 2835102 DOI: 10.1016/0005-2736(88)90008-9  1
1987 Ellena JF, Dominey RN, Archer SJ, Xu ZC, Cafiso DS. Localization of hydrophobic ions in phospholipid bilayers using 1H nuclear Overhauser effect spectroscopy. Biochemistry. 26: 4584-92. PMID 3663609 DOI: 10.1021/Bi00388A062  0.84
1987 Perkins WR, Cafiso DS. Characterization of H+/OH- currents in phospholipid vesicles. Journal of Bioenergetics and Biomembranes. 19: 443-55. PMID 3320038 DOI: 10.1007/Bf00770029  1
1987 Hartsel SC, Moore CR, Raines DE, Cafiso DS. Time-dependent binding of paramagnetic and fluorescent hydrophobic ions to the acetylcholine receptor from Torpedo. Biochemistry. 26: 3253-60. PMID 2820466 DOI: 10.1021/Bi00386A003  1
1987 Perkins WR, Cafiso DS. Procedure using voltage-sensitive spin-labels to monitor dipole potential changes in phospholipid vesicles: The estimation of phloretin-induced conductance changes in vesicles The Journal of Membrane Biology. 96: 165-173. DOI: 10.1007/Bf01869242  1
1987 Ellena JF, Dominey RN, Cafiso DS. Molecular dynamics in sodium dodecyl sulfate micelles elucidated using 13C and 1H spin-lattice relaxation, 13C spin-spin relaxation, and 1H nuclear Overhauser effect spectroscopy Journal of Physical Chemistry. 91: 131-137.  1
1986 Xu ZC, Cafiso DS. Phospholipid packing and conformation in small vesicles revealed by two-dimensional 1H nuclear magnetic resonance cross-relaxation spectroscopy. Biophysical Journal. 49: 779-83. PMID 3754469 DOI: 10.1016/S0006-3495(86)83705-5  1
1986 Perkins WR, Cafiso DS. An electrical and structural characterization of H+/OH- currents in phospholipid vesicles. Biochemistry. 25: 2270-6. PMID 3707945 DOI: 10.1021/Bi00356A063  1
1986 McDaniel RV, Sharp K, Brooks D, McLaughlin AC, Winiski AP, Cafiso D, McLaughlin S. Electrokinetic and electrostatic properties of bilayers containing gangliosides GM1, GD1a, or GT1. Comparison with a nonlinear theory. Biophysical Journal. 49: 741-52. PMID 3697476 DOI: 10.1016/S0006-3495(86)83700-6  1
1986 Cafiso DS. Electron paramagnetic resonance methods for measuring H+/OH- fluxes across phospholipid vesicles. Methods in Enzymology. 127: 502-10. PMID 3016469 DOI: 10.1016/0076-6879(86)27040-8  1
1986 Cline DS, Cafiso DS. Reconstitution of an electrically active conformational transition in rhodopsin-containing membranes Bba - Biomembranes. 854: 151-155. DOI: 10.1016/0005-2736(86)90076-3  1
1985 Ellena JF, Hutton WC, Cafiso DS. Elucidation of cross-relaxation pathways in phospholipid vesicles utilizing two-dimensional proton NMR spectroscopy Journal of the American Chemical Society. 107: 1530-1537. DOI: 10.1021/Ja00292A013  0.84
1985 Ellena JF, Hutton WC, Cafiso DS. Elucidation Of Cross-Relaxation Pathways In Phospholipid Vesicles Utilizing Two-Dimensional Proton Nmr Spectroscopy Cheminform. 16. DOI: 10.1002/Chin.198530046  0.84
1985 Ellena JF, Hutton WC, Cafiso DS. Elucidation of cross-relaxation pathways in phospholipid vesicles utilizing two-dimensional 1H NMR spectroscopy Journal of the American Chemical Society. 107: 1530-1537.  1
1984 Raines DE, Cafiso DS. Potential-dependent phase partitioning of fluorescent hydrophobic ions in phospholipid vesicles. The Journal of Membrane Biology. 82: 241-7. PMID 6530698 DOI: 10.1007/Bf01871633  1
1983 Cafiso DS, Hubbell WL. Electrogenic H+/OH- movement across phospholipid vesicles measured by spin-labeled hydrophobic ions. Biophysical Journal. 44: 49-57. PMID 6313085 DOI: 10.1016/S0006-3495(83)84276-3  1
1982 Cafiso DS, Hubbell WL. Transmembrane electrical currents of spin-labeled hydrophobic ions. Biophysical Journal. 39: 263-72. PMID 7139025 DOI: 10.1016/S0006-3495(82)84516-5  1
1982 Cafiso DS, Hubel WL, Quintanilha A. [83] Spin-label probes of light-induced electrical potentials in rhodopsin and bacteriorhodopsin Methods in Enzymology. 88: 682-696. DOI: 10.1016/0076-6879(82)88086-5  1
1982 Cafiso DS, Hubbell WL. EPR PROBES OF MEMBRANE ELECTROSTATICS Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 68.  1
1981 Cafiso DS, Hubbell WL. EPR determination of membrane potentials. Annual Review of Biophysics and Bioengineering. 10: 217-44. PMID 6266334 DOI: 10.1146/  1
1981 Cafiso DS, Petty HR, McConnell HM. Preparation of unilamellar lipid vesicles at 37°C by vaporization methods Bba - Biomembranes. 649: 129-132. DOI: 10.1016/0005-2736(81)90018-3  1
1980 Cafiso DS, Hubbell WL. Interfacial charge separation in photoreceptor memebranes. Photochemistry and Photobiology. 32: 461-8. PMID 7454850 DOI: 10.1111/J.1751-1097.1980.Tb03789.X  1
1980 Cafiso DS, Hubbell WL. Light-induced interfacial potentials in photoreceptor membranes. Biophysical Journal. 30: 243-63. PMID 6266528 DOI: 10.1016/S0006-3495(80)85092-2  1
1978 Cafiso DS, Hubbell WL. Estimation of transmembrane potentials from phase equilibria of hydrophobic paramagnetic ions. Biochemistry. 17: 187-95. PMID 201283 DOI: 10.1021/Bi00594A028  1
1978 Cafiso DS, Hubbell WL. Estimation of transmembrane pH gradients from phase equilibria of spin-labeled amines. Biochemistry. 17: 3871-7. PMID 29663 DOI: 10.1021/Bi00611A030  1
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