Year |
Citation |
Score |
2019 |
Adusumalli S, Jamwal R, Leggio L, Akhlaghi F. Development and validation of an assay for a novel ghrelin receptor inverse agonist PF-5190457 and its major hydroxy metabolite (PF-6870961) by LC-MS/MS in human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1130: 121820. PMID 31670107 DOI: 10.1016/J.Jchromb.2019.121820 |
0.535 |
|
2019 |
Adusumalli S, Jamwal R, Obach RS, Ryder TF, Leggio L, Akhlaghi F. Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 31182423 DOI: 10.1124/Dmd.119.087015 |
0.32 |
|
2018 |
Jamwal R, de la Monte SM, Ogasawara K, Adusumalli S, Barlock BB, Akhlaghi F. Nonalcoholic fatty liver disease and diabetes is associated with decreased CYP3A4 protein expression and activity in human liver. Molecular Pharmaceutics. PMID 29792708 DOI: 10.1021/Acs.Molpharmaceut.8B00159 |
0.334 |
|
2018 |
Ghareeb M, Gohh RY, Akhlaghi F. Tacrolimus Concentration in Saliva of Kidney Transplant Recipients: Factors Influencing the Relationship with Whole Blood Concentrations. Clinical Pharmacokinetics. PMID 29330784 DOI: 10.1007/S40262-017-0626-1 |
0.34 |
|
2018 |
Jamwal R, Barlock BJ, Adusumalli S, Ogasawara K, Simons BL, Akhlaghi F. Use of SWATH-MS to relatively quantify the expression of hepatic drug metabolizing enzymes in human liver microsomes using a label-free approach Drug Metabolism and Pharmacokinetics. 33: S57-S58. DOI: 10.1016/J.Dmpk.2017.11.195 |
0.311 |
|
2017 |
Valanejad L, Ghareeb M, Shiffka S, Nadolny C, Chen Y, Guo L, Verma R, You S, Akhlaghi F, Deng R. Dysregulation of Δ(4)-3-oxosteroid 5β-reductase in diabetic patients: Implications and mechanisms. Molecular and Cellular Endocrinology. PMID 29024782 DOI: 10.1016/J.Mce.2017.10.005 |
0.311 |
|
2017 |
Jamwal R, Barlock BJ, Adusumalli S, Ogasawara K, Simons BL, Akhlaghi F. A multiplex and label-free relative quantification approach for studying protein abundance of drug metabolizing enzymes in human liver microsomes using SWATH-MS. Journal of Proteome Research. PMID 28944677 DOI: 10.1021/Acs.Jproteome.7B00505 |
0.401 |
|
2017 |
Lee MR, Scheidweiler KB, Diao XX, Akhlaghi F, Cummins A, Huestis MA, Leggio L, Averbeck BB. Oxytocin by intranasal and intravenous routes reaches the cerebrospinal fluid in rhesus macaques: determination using a novel oxytocin assay. Molecular Psychiatry. PMID 28289281 DOI: 10.1038/Mp.2017.27 |
0.307 |
|
2017 |
Jamwal R, Topletz AR, Ramratnam B, Akhlaghi F. Ultra-high performance liquid chromatography tandem mass-spectrometry for simple and simultaneous quantification of cannabinoids. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1048: 10-18. PMID 28192758 DOI: 10.1016/J.Jchromb.2017.02.007 |
0.506 |
|
2016 |
Ghareeb M, Akhlaghi F. Development and validation of a sensitive and selective LC-MS/MS method for determination of tacrolimus in oral fluids. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. PMID 27771258 DOI: 10.1016/J.Jchromb.2016.10.008 |
0.518 |
|
2015 |
Ghareeb M, Akhlaghi F. Alternative matrices for therapeutic drug monitoring of immunosuppressive agents using LC-MS/MS. Bioanalysis. 7: 1037-58. PMID 25966013 DOI: 10.4155/Bio.15.35 |
0.442 |
|
2015 |
Ghareeb M, Leggio L, El-Kattan A, Akhlaghi F. Development and validation of an UPLC-MS/MS assay for quantitative analysis of the ghrelin receptor inverse agonist PF-5190457 in human or rat plasma and rat brain. Analytical and Bioanalytical Chemistry. 407: 5603-13. PMID 25943263 DOI: 10.1007/S00216-015-8730-2 |
0.476 |
|
2014 |
Robertsen I, Asberg A, Granseth T, Vethe NT, Akhlaghi F, Ghareeb M, Molden E, Reier-Nilsen M, Holdaas H, Midtvedt K. More potent lipid-lowering effect by rosuvastatin compared with fluvastatin in everolimus-treated renal transplant recipients. Transplantation. 97: 1266-71. PMID 24521776 DOI: 10.1097/01.Tp.0000443225.66960.7E |
0.303 |
|
2014 |
Ionita IA, Ogasawara K, Gohh RY, Akhlaghi F. Pharmacokinetics of total and unbound prednisone and prednisolone in stable kidney transplant recipients with diabetes mellitus. Therapeutic Drug Monitoring. 36: 448-55. PMID 24452065 DOI: 10.1097/Ftd.0000000000000045 |
0.781 |
|
2013 |
Dostalek M, Gohh RY, Akhlaghi F. Inosine monophosphate dehydrogenase expression and activity are significantly lower in kidney transplant recipients with diabetes mellitus. Therapeutic Drug Monitoring. 35: 374-83. PMID 23666569 DOI: 10.1097/Ftd.0B013E3182852697 |
0.4 |
|
2013 |
Ogasawara K, Chitnis SD, Gohh RY, Christians U, Akhlaghi F. Multidrug resistance-associated protein 2 (MRP2/ABCC2) haplotypes significantly affect the pharmacokinetics of tacrolimus in kidney transplant recipients. Clinical Pharmacokinetics. 52: 751-62. PMID 23633119 DOI: 10.1007/S40262-013-0069-2 |
0.762 |
|
2013 |
Chitnis SD, Ogasawara K, Schniedewind B, Gohh RY, Christians U, Akhlaghi F. Concentration of tacrolimus and major metabolites in kidney transplant recipients as a function of diabetes mellitus and cytochrome P450 3A gene polymorphism. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 43: 641-9. PMID 23278282 DOI: 10.3109/00498254.2012.752118 |
0.775 |
|
2012 |
Dostalek M, Sam WJ, Paryani KR, Macwan JS, Gohh RY, Akhlaghi F. Diabetes mellitus reduces the clearance of atorvastatin lactone: results of a population pharmacokinetic analysis in renal transplant recipients and in vitro studies using human liver microsomes. Clinical Pharmacokinetics. 51: 591-606. PMID 22775412 DOI: 10.2165/11632690-000000000-00000 |
0.382 |
|
2012 |
Dostalek M, Akhlaghi F, Puzanovova M. Effect of diabetes mellitus on pharmacokinetic and pharmacodynamic properties of drugs. Clinical Pharmacokinetics. 51: 481-99. PMID 22668340 DOI: 10.2165/11631900-000000000-00000 |
0.329 |
|
2012 |
Akhlaghi F, Dostalek M, Falck P, Mendonza AE, Amundsen R, Gohh RY, Asberg A. The concentration of cyclosporine metabolites is significantly lower in kidney transplant recipients with diabetes mellitus. Therapeutic Drug Monitoring. 34: 38-45. PMID 22210099 DOI: 10.1097/Ftd.0B013E318241Ac71 |
0.769 |
|
2012 |
Macwan JS, Ionita IA, Akhlaghi F. A simple assay for the simultaneous determination of rosuvastatin acid, rosuvastatin-5S-lactone, and N-desmethyl rosuvastatin in human plasma using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Analytical and Bioanalytical Chemistry. 402: 1217-27. PMID 22108655 DOI: 10.1007/S00216-011-5548-4 |
0.81 |
|
2012 |
Dostalek M, Sam W, Paryani KR, Macwan JS, Gohh RY, Akhlaghi F. Diabetes Mellitus Reduces the Clearance of Atorvastatin Lactone Clinical Pharmacokinetics. 51: 591-606. DOI: 10.1007/Bf03261933 |
0.354 |
|
2011 |
Bolin P, Gohh R, Kandaswamy R, Shihab FS, Wiland A, Akhlaghi F, Melancon K. Mycophenolic acid in kidney transplant patients with diabetes mellitus: does the formulation matter? Transplantation Reviews (Orlando, Fla.). 25: 117-23. PMID 21530217 DOI: 10.1016/J.Trre.2010.12.003 |
0.386 |
|
2011 |
Macwan JS, Ionita IA, Dostalek M, Akhlaghi F. Development and validation of a sensitive, simple, and rapid method for simultaneous quantitation of atorvastatin and its acid and lactone metabolites by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Analytical and Bioanalytical Chemistry. 400: 423-33. PMID 21359569 DOI: 10.1007/S00216-011-4804-Y |
0.812 |
|
2011 |
Dostalek M, Court MH, Yan B, Akhlaghi F. Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus. British Journal of Pharmacology. 163: 937-47. PMID 21323901 DOI: 10.1111/J.1476-5381.2011.01270.X |
0.339 |
|
2011 |
Dostalek M, Court MH, Hazarika S, Akhlaghi F. Diabetes mellitus reduces activity of human UDP-glucuronosyltransferase 2B7 in liver and kidney leading to decreased formation of mycophenolic acid acyl-glucuronide metabolite. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 448-55. PMID 21123165 DOI: 10.1124/Dmd.110.036608 |
0.383 |
|
2011 |
Elshafeey A, Hamza Y, Amin S, Akhlaghi F. Enhanced Bioavailability of Fenoterol Transdermal Systems in Rabbits Journal of Bioequivalence & Bioavailability. 3. DOI: 10.4172/Jbb.1000067 |
0.456 |
|
2010 |
Hu S, Akhlaghi F, Chitnis S, Chiu R, Go S, Rout P, Steffes M, Abbott JD, Dworkin L, Bostom A. Comparison of plasma clearance of iodixanol during versus after angiography. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 56: 1219-20. PMID 21094917 DOI: 10.1053/J.Ajkd.2010.08.020 |
0.765 |
|
2010 |
Narwal R, Akhlaghi F, Asberg A, Hermann M, Rosenbaum SE. Development of a population pharmacokinetic model for atorvastatin acid and its lactone metabolite. Clinical Pharmacokinetics. 49: 693-702. PMID 20818835 DOI: 10.2165/11535980-000000000-00000 |
0.31 |
|
2010 |
Ionita IA, Akhlaghi F. Quantification of unbound prednisolone, prednisone, cortisol and cortisone in human plasma by ultrafiltration and direct injection into liquid chromatrography tandem mass spectrometry. Annals of Clinical Biochemistry. 47: 350-7. PMID 20592334 DOI: 10.1258/Acb.2010.010027 |
0.798 |
|
2010 |
Dostalek M, Macwan JS, Chitnis SD, Ionita IA, Akhlaghi F. Development and validation of a rapid and sensitive assay for simultaneous quantification of midazolam, 1'-hydroxymidazolam, and 4-hydroxymidazolam by liquid chromatography coupled to tandem mass-spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 878: 1629-33. PMID 20434409 DOI: 10.1016/J.Jchromb.2010.04.001 |
0.767 |
|
2010 |
Lin S, Henning AK, Akhlaghi F, Reisfield R, Vergara-Silva A, First MR. INTERLEUKIN-2 RECEPTOR ANTAGONIST INDUCTION THERAPY LEADS TO INCREASED TACROLIMUS LEVELS AFTER KIDNEY TRANSPLANTATION Transplantation Journal. 90: 69. DOI: 10.1097/00007890-201007272-00130 |
0.3 |
|
2009 |
Ionita IA, Fast DM, Akhlaghi F. Development of a sensitive and selective method for the quantitative analysis of cortisol, cortisone, prednisolone and prednisone in human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 877: 765-72. PMID 19237320 DOI: 10.1016/J.Jchromb.2009.02.019 |
0.813 |
|
2009 |
Sam WJ, Akhlaghi F, Rosenbaum SE. Population pharmacokinetics of mycophenolic acid and its 2 glucuronidated metabolites in kidney transplant recipients. Journal of Clinical Pharmacology. 49: 185-95. PMID 19179297 DOI: 10.1177/0091270008329558 |
0.415 |
|
2008 |
Mendonza AE, Gohh RY, Akhlaghi F. Blood and plasma pharmacokinetics of ciclosporin in diabetic kidney transplant recipients. Clinical Pharmacokinetics. 47: 733-42. PMID 18840028 DOI: 10.2165/00003088-200847110-00004 |
0.786 |
|
2008 |
Chitnis SD, Akhlaghi F. Development and validation of an HPLC-UV method for iodixanol quantification in human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 869: 133-7. PMID 18502708 DOI: 10.1016/J.Jchromb.2008.05.002 |
0.805 |
|
2008 |
Pabla D, Akhlaghi F, Ahmed A, Zia H. Development and validation of an inductively coupled plasma mass spectrometry method for quantification of levothyroxine in dissolution studies. Rapid Communications in Mass Spectrometry : Rcm. 22: 993-6. PMID 18320549 DOI: 10.1002/Rcm.3457 |
0.476 |
|
2008 |
Falck P, Asberg A, Guldseth H, Bremer S, Akhlaghi F, Reubsaet JL, Pfeffer P, Hartmann A, Midtvedt K. Declining intracellular T-lymphocyte concentration of cyclosporine a precedes acute rejection in kidney transplant recipients. Transplantation. 85: 179-84. PMID 18212621 DOI: 10.1097/Tp.0B013E31815Feede |
0.361 |
|
2007 |
Patel CG, Richman K, Yang D, Yan B, Gohh RY, Akhlaghi F. Effect of diabetes mellitus on mycophenolate sodium pharmacokinetics and inosine monophosphate dehydrogenase activity in stable kidney transplant recipients. Therapeutic Drug Monitoring. 29: 735-42. PMID 18043470 DOI: 10.1097/Ftd.0B013E31815D8Ace |
0.41 |
|
2007 |
Mendonza AE, Zahir H, Gohh RY, Akhlaghi F. Tacrolimus in diabetic kidney transplant recipients: pharmacokinetics and application of a limited sampling strategy. Therapeutic Drug Monitoring. 29: 391-8. PMID 17667791 DOI: 10.1097/Ftd.0B013E31811F319B |
0.783 |
|
2007 |
Patel CG, Harmon M, Gohh RY, Akhlaghi F. Concentrations of mycophenolic acid and glucuronide metabolites under concomitant therapy with cyclosporine or tacrolimus. Therapeutic Drug Monitoring. 29: 87-95. PMID 17304155 DOI: 10.1097/Ftd.0B013E3180318C35 |
0.381 |
|
2006 |
Zahir H, Keogh AM, Akhlaghi F. Apparent clearance of sirolimus in heart transplant recipients: impact of primary diagnosis and serum lipids. Therapeutic Drug Monitoring. 28: 614-22. PMID 17038875 DOI: 10.1097/01.Ftd.0000246765.05248.Fa |
0.372 |
|
2006 |
Mendonza AE, Gohh RY, Akhlaghi F. Analysis of mycophenolic acid in saliva using liquid chromatography tandem mass spectrometry. Therapeutic Drug Monitoring. 28: 402-6. PMID 16778726 DOI: 10.1097/01.ftd.0000211826.65607.05 |
0.795 |
|
2006 |
Patel CG, Akhlaghi F. High-performance liquid chromatography method for the determination of mycophenolic acid and its acyl and phenol glucuronide metabolites in human plasma. Therapeutic Drug Monitoring. 28: 116-22. PMID 16418705 DOI: 10.1097/01.Ftd.0000177664.96726.56 |
0.49 |
|
2006 |
Akhlaghi F, Patel CG, Zuniga XP, Halilovic J, Preis IS, Gohh RY. Pharmacokinetics of mycophenolic acid and metabolites in diabetic kidney transplant recipients. Therapeutic Drug Monitoring. 28: 95-101. PMID 16418701 DOI: 10.1097/01.Ftd.0000189898.23931.3F |
0.45 |
|
2005 |
Akhlaghi F, Gonzalez L, Trull AK. Association between cyclosporine concentrations at 2 hours post-dose and clinical outcomes in de novo lung transplant recipients. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 24: 2120-8. PMID 16364860 DOI: 10.1016/J.Healun.2005.05.005 |
0.32 |
|
2005 |
Zahir H, McLachlan AJ, Nelson A, McCaughan G, Gleeson M, Akhlaghi F. Population pharmacokinetic estimation of tacrolimus apparent clearance in adult liver transplant recipients. Therapeutic Drug Monitoring. 27: 422-30. PMID 16044097 DOI: 10.1097/01.Ftd.0000170029.36573.A0 |
0.349 |
|
2005 |
Rosenbaum SE, Baheti G, Trull AK, Akhlaghi F. Population pharmacokinetics of cyclosporine in cardiopulmonary transplant recipients. Therapeutic Drug Monitoring. 27: 116-22. PMID 15795639 DOI: 10.1097/01.Ftd.0000148448.51225.2C |
0.339 |
|
2005 |
Soman RS, Zahir H, Akhlaghi F. Development and validation of an HPLC-UV method for determination of iohexol in human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 816: 339-43. PMID 15664368 DOI: 10.1016/J.Jchromb.2004.11.046 |
0.487 |
|
2004 |
Patel CG, Mendonza AE, Akhlaghi F, Majid O, Trull AK, Lee T, Holt DW. Determination of total mycophenolic acid and its glucuronide metabolite using liquid chromatography with ultraviolet detection and unbound mycophenolic acid using tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 813: 287-94. PMID 15556544 DOI: 10.1016/J.Jchromb.2004.10.004 |
0.8 |
|
2004 |
Mendonza A, Gohh R, Akhlaghi F. Determination of cyclosporine in saliva using liquid chromatography-tandem mass spectrometry. Therapeutic Drug Monitoring. 26: 569-75. PMID 15385841 DOI: 10.1097/00007691-200410000-00016 |
0.798 |
|
2004 |
Trull AK, Akhlaghi F, Charman SC, Endenberg S, Majid O, Cornelissen J, Steel L, Parameshwar J, Wallwork J, Large S. Immunosuppression, eotaxin and the diagnostic changes in eosinophils that precede early acute heart allograft rejection. Transplant Immunology. 12: 159-66. PMID 14967314 DOI: 10.1016/S0966-3274(03)00077-7 |
0.413 |
|
2002 |
Akhlaghi F, Trull AK. Distribution of cyclosporin in organ transplant recipients. Clinical Pharmacokinetics. 41: 615-37. PMID 12126456 DOI: 10.2165/00003088-200241090-00001 |
0.436 |
|
2001 |
Akhlaghi F, Keogh AM, McLachlan AJ, Kaan A. Pharmacokinetics of cyclosporine in heart transplant recipients receiving metabolic inhibitors. The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 20: 431-8. PMID 11295581 DOI: 10.1016/S1053-2498(00)00234-5 |
0.352 |
|
2001 |
Majid O, Akhlaghi F, Lee T, Holt DW, Trull A. Simultaneous determination of plasma prednisolone, prednisone, and cortisol levels by high-performance liquid chromatography. Therapeutic Drug Monitoring. 23: 163-8. PMID 11294518 DOI: 10.1097/00007691-200104000-00012 |
0.497 |
|
2000 |
Trull AK, Steel LA, Sharples LD, Akhlaghi F, Parameshwar J, Cary N, Wallwork J, Large S. Randomized trial of blood eosinophil count monitoring as a guide to corticosteroid dosage adjustment after heart transplantation Transplantation. 70: 802-809. PMID 11003362 DOI: 10.1097/00007890-200009150-00017 |
0.369 |
|
1999 |
Akhlaghi F, Ashley J, Keogh A, Brown K. Cyclosporine plasma unbound fraction in heart and lung transplantation recipients. Therapeutic Drug Monitoring. 21: 8-16. PMID 10051049 DOI: 10.1097/00007691-199902000-00003 |
0.389 |
|
1999 |
Akhlaghi F, Keogh AM, Brown KF. Unbound cyclosporine and allograft rejection after heart transplantation. Transplantation. 67: 54-9. PMID 9921795 DOI: 10.1097/00007890-199901150-00008 |
0.387 |
|
1998 |
Akhlaghi F, Ashley JJ, Keogh AM, Brown KF. Indirect estimation of the unbound fraction of cyclosporine in plasma. Therapeutic Drug Monitoring. 20: 301-8. PMID 9631927 DOI: 10.1097/00007691-199806000-00010 |
0.353 |
|
1997 |
Akhlaghi F, McLachlan AJ, Keogh AM, Brown KF. Effect of simvastatin on cyclosporine unbound fraction and apparent blood clearance in heart transplant recipients. British Journal of Clinical Pharmacology. 44: 537-42. PMID 9431828 DOI: 10.1046/J.1365-2125.1997.T01-1-00625.X |
0.331 |
|
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