| Year |
Citation |
Score |
| 2024 |
Yang F, Beltran-Lobo P, Sung K, Goldrick C, Croft CL, Nishimura A, Hedges E, Mahiddine F, Troakes C, Golde TE, Perez-Nievas BG, Hanger DP, Noble W, Jimenez-Sanchez M. Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection. Science Advances. 10: eadk9884. PMID 38507480 DOI: 10.1126/sciadv.adk9884 |
0.641 |
|
| 2024 |
Utton MA, Noble WJ, Hill JE, Anderton BH, Hanger DP. Expression of Concern: Molecular motors implicated in the axonal transport of tau and α-synuclein. Journal of Cell Science. 137. PMID 38345345 DOI: 10.1242/jcs.261985 |
0.52 |
|
| 2023 |
Lyu C, Da Vela S, Al-Hilaly Y, Marshall KE, Thorogate R, Svergun D, Serpell LC, Pastore A, Hanger DP. Corrigendum: The disease associated Tau35 fragment has an increased propensity to aggregate compared to full-length tau. Frontiers in Molecular Biosciences. 10: 1276677. PMID 37790876 DOI: 10.3389/fmolb.2023.1276677 |
0.438 |
|
| 2023 |
Marzi SJ, Schilder BM, Nott A, Frigerio CS, Willaime-Morawek S, Bucholc M, Hanger DP, James C, Lewis PA, Lourida I, Noble W, Rodriguez-Algarra F, Sharif JA, Tsalenchuk M, Winchester LM, et al. Artificial intelligence for neurodegenerative experimental models. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37768001 DOI: 10.1002/alz.13479 |
0.471 |
|
| 2023 |
Beltran-Lobo P, Hughes MM, Troakes C, Croft CL, Rupawala H, Jutzi D, Ruepp MD, Jimenez-Sanchez M, Perkinton MS, Kassiou M, Golde TE, Hanger DP, Verkhratsky A, Perez-Nievas BG, Noble W. P2XR influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes. Brain, Behavior, and Immunity. 114: 414-429. PMID 37716378 DOI: 10.1016/j.bbi.2023.09.011 |
0.684 |
|
| 2023 |
Noble W, Hanger DP. Trimming away tau in neurodegeneration. Science (New York, N.Y.). 381: 377-378. PMID 37499007 DOI: 10.1126/science.adj0256 |
0.65 |
|
| 2021 |
Pollack SJ, Dakkak D, Guo T, Gómez-Suaga P, Noble W, Hanger DP. Autophagy and lysosomal defects in cells expressing disease-associated tau. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058299. PMID 34971173 DOI: 10.1002/alz.058299 |
0.723 |
|
| 2021 |
Goniotaki D, Tamagnini F, Biasetti L, Rumpf SL, Troakes C, Pollack SJ, Ukwesa S, Sun H, Serpell L, Noble W, Staras K, Hanger DP. HCN channelopathy couples disease-associated tau to synaptic dysfunction. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058346. PMID 34971152 DOI: 10.1002/alz.058346 |
0.6 |
|
| 2021 |
Lyu C, Da Vela S, Al-Hilaly Y, Marshall KE, Thorogate R, Svergun D, Serpell LC, Pastore A, Hanger DP. The Disease Associated Tau35 Fragment has an Increased Propensity to Aggregate Compared to Full-Length Tau. Frontiers in Molecular Biosciences. 8: 779240. PMID 34778381 DOI: 10.3389/fmolb.2021.779240 |
0.519 |
|
| 2020 |
Glennon EB, Lau DH, Gabriele RMC, Taylor MF, Troakes C, Opie-Martin S, Elliott C, Killick R, Hanger DP, Perez-Nievas BG, Noble W. Bridging Integrator-1 protein loss in Alzheimer's disease promotes synaptic tau accumulation and disrupts tau release. Brain Communications. 2. PMID 32500121 DOI: 10.1093/braincomms/fcaa011 |
0.747 |
|
| 2020 |
Glennon EB, Lau DHW, Gabriele RMC, Taylor MF, Troakes C, Opie-Martin S, Elliott C, Killick R, Hanger DP, Perez-Nievas BG, Noble W. Bridging integrator 1 protein loss in Alzheimer’s disease promotes synaptic tau accumulation and disrupts tau release Brain Communications. 2. DOI: 10.1093/braincomms/fcaa011 |
0.583 |
|
| 2019 |
Hanger DP, Goniotaki D, Noble W. Synaptic Localisation of Tau. Advances in Experimental Medicine and Biology. 1184: 105-112. PMID 32096032 DOI: 10.1007/978-981-32-9358-8_9 |
0.721 |
|
| 2019 |
Noble W, Jimenez-Sanchez M, Perez-Nievas BG, Hanger DP. Considerations for future tau-targeted therapeutics: can they deliver? Expert Opinion On Drug Discovery. 1-3. PMID 31661994 DOI: 10.1080/17460441.2020.1685977 |
0.587 |
|
| 2019 |
Guo T, Dakkak D, Rodriguez-Martin T, Noble W, Hanger DP. A pathogenic tau fragment compromises microtubules, disrupts insulin signaling and induces the unfolded protein response. Acta Neuropathologica Communications. 7: 2. PMID 30606258 DOI: 10.1186/s40478-018-0651-9 |
0.708 |
|
| 2018 |
Lionnet A, Wade MA, Corbillé AG, Prigent A, Paillusson S, Tasselli M, Gonzales J, Durieu E, Rolli-Derkinderen M, Coron E, Duchalais E, Neunlist M, Perkinton MS, Hanger DP, Noble W, et al. Characterisation of tau in the human and rodent enteric nervous system under physiological conditions and in tauopathy. Acta Neuropathologica Communications. 6: 65. PMID 30037345 DOI: 10.1186/S40478-018-0568-3 |
0.72 |
|
| 2018 |
Giacomini C, Koo CY, Yankova N, Tavares IA, Wray S, Noble W, Hanger DP, Morris JDH. A new TAO kinase inhibitor reduces tau phosphorylation at sites associated with neurodegeneration in human tauopathies. Acta Neuropathologica Communications. 6: 37. PMID 29730992 DOI: 10.1186/S40478-018-0539-8 |
0.79 |
|
| 2017 |
Tamagnini F, Walsh DA, Brown JT, Bondulich MK, Hanger DP, Randall AD. Hippocampal neurophysiology is modified by a disease-associated C-terminal fragment of tau protein. Neurobiology of Aging. 60: 44-56. PMID 28917666 DOI: 10.1016/J.Neurobiolaging.2017.07.005 |
0.43 |
|
| 2017 |
Croft CL, Kurbatskaya K, Hanger DP, Noble W. Inhibition of glycogen synthase kinase-3 by BTA-EG4 reduces tau abnormalities in an organotypic brain slice culture model of Alzheimer's disease. Scientific Reports. 7: 7434. PMID 28785087 DOI: 10.1038/S41598-017-07906-1 |
0.688 |
|
| 2017 |
Guo T, Noble W, Hanger DP. Roles of tau protein in health and disease. Acta Neuropathologica. PMID 28386764 DOI: 10.1007/s00401-017-1707-9 |
0.715 |
|
| 2017 |
Paillusson S, Gomez-Suaga P, Stoica R, Little D, Gissen P, Devine MJ, Noble W, Hanger DP, Miller CC. α-Synuclein binds to the ER-mitochondria tethering protein VAPB to disrupt Ca(2+) homeostasis and mitochondrial ATP production. Acta Neuropathologica. PMID 28337542 DOI: 10.1007/S00401-017-1704-Z |
0.542 |
|
| 2017 |
Croft CL, Wade MA, Kurbatskaya K, Mastrandreas P, Hughes MM, Phillips EC, Pooler AM, Perkinton MS, Hanger DP, Noble W. Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures. Cell Death & Disease. 8: e2671. PMID 28300838 DOI: 10.1038/Cddis.2017.97 |
0.819 |
|
| 2017 |
Gomez-Suaga P, Paillusson S, Stoica R, Noble W, Hanger DP, Miller CC. The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy. Current Biology : Cb. PMID 28132811 DOI: 10.1016/J.Cub.2016.12.038 |
0.468 |
|
| 2017 |
Hanger DP, Croft CL, Lau DH, Noble W. ACTIVITY-DEPENDENT TAU RELEASE: IMPLICATIONS FOR TAU PROPAGATION Alzheimer's & Dementia. 13: P888. DOI: 10.1016/J.Jalz.2017.07.288 |
0.661 |
|
| 2017 |
Giacomini C, Noble W, Hanger DP, Morris JD. [P1-223]: FUNCTIONAL ROLES FOR TAOK KINASES IN THE DEVELOPMENT OF TAU PATHOLOGY IN ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P328-P329. DOI: 10.1016/J.Jalz.2017.06.043 |
0.676 |
|
| 2016 |
Stoica R, Paillusson S, Gomez-Suaga P, Mitchell JC, Lau DH, Gray EH, Sancho RM, Vizcay-Barrena G, De Vos KJ, Shaw CE, Hanger DP, Noble W, Miller CC. ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations. Embo Reports. PMID 27418313 DOI: 10.15252/Embr.201541726 |
0.512 |
|
| 2016 |
Bondulich MK, Guo T, Meehan C, Manion J, Rodriguez Martin T, Mitchell JC, Hortobagyi T, Yankova N, Stygelbout V, Brion JP, Noble W, Hanger DP. Tauopathy induced by low level expression of a human brain-derived tau fragment in mice is rescued by phenylbutyrate. Brain : a Journal of Neurology. PMID 27297240 DOI: 10.1093/Brain/Aww137 |
0.693 |
|
| 2016 |
Lau DH, Hogseth M, Phillips EC, O'Neill MJ, Pooler AM, Noble W, Hanger DP. Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer's disease. Acta Neuropathologica Communications. 4: 49. PMID 27193083 DOI: 10.1186/S40478-016-0317-4 |
0.848 |
|
| 2016 |
Kurbatskaya K, Phillips EC, Croft CL, Dentoni G, Hughes MM, Wade MA, Al-Sarraj S, Troakes C, O'Neill MJ, Perez-Nievas BG, Hanger DP, Noble W. Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain. Acta Neuropathologica Communications. 4: 34. PMID 27036949 DOI: 10.1186/S40478-016-0299-2 |
0.648 |
|
| 2016 |
Gilley J, Ando K, Seereeram A, Rodríguez-Martín T, Pooler AM, Sturdee L, Anderton BH, Brion JP, Hanger DP, Coleman MP. Mislocalization of neuronal tau in the absence of tangle pathology in phosphomutant tau knockin mice. Neurobiology of Aging. 39: 1-18. PMID 26923397 DOI: 10.1016/j.neurobiolaging.2015.11.028 |
0.817 |
|
| 2015 |
Rodríguez-Martín T, Pooler AM, Lau DH, Mórotz GM, De Vos KJ, Gilley J, Coleman MP, Hanger DP. Reduced number of axonal mitochondria and tau hypophosphorylation in mouse P301L tau knockin neurons. Neurobiology of Disease. 85: 1-10. PMID 26459111 DOI: 10.1016/j.nbd.2015.10.007 |
0.781 |
|
| 2015 |
Croft CL, Hanger DP, Noble W. P3-054: The amyloid-binding agent bta-eg4
reduces pathological tau species in a novel organotypic 3xTg-AD brain slice culture model that recapitulates key in vivo
degenerative phenotypes Alzheimer's & Dementia. 11: P639-P639. DOI: 10.1016/J.Jalz.2015.06.921 |
0.617 |
|
| 2014 |
Phillips EC, Croft CL, Kurbatskaya K, O'Neill MJ, Hutton ML, Hanger DP, Garwood CJ, Noble W. Astrocytes and neuroinflammation in Alzheimer's disease. Biochemical Society Transactions. 42: 1321-5. PMID 25233410 DOI: 10.1042/Bst20140155 |
0.662 |
|
| 2014 |
Hanger DP, Lau DH, Phillips EC, Bondulich MK, Guo T, Woodward BW, Pooler AM, Noble W. Intracellular and extracellular roles for tau in neurodegenerative disease. Journal of Alzheimer's Disease : Jad. 40: S37-45. PMID 24595196 DOI: 10.3233/Jad-132054 |
0.843 |
|
| 2014 |
Povellato G, Tuxworth RI, Hanger DP, Tear G. Modification of the Drosophila model of in vivo Tau toxicity reveals protective phosphorylation by GSK3β. Biology Open. 3: 1-11. PMID 24429107 DOI: 10.1242/Bio.20136692 |
0.536 |
|
| 2014 |
Pooler AM, Noble W, Hanger DP. A role for tau at the synapse in Alzheimer's disease pathogenesis. Neuropharmacology. 76: 1-8. PMID 24076336 DOI: 10.1016/J.Neuropharm.2013.09.018 |
0.802 |
|
| 2014 |
Atherton J, Kurbatskaya K, Bondulich M, Croft CL, Garwood CJ, Chhabra R, Wray S, Jeromin A, Hanger DP, Noble W. Calpain cleavage and inactivation of the sodium calcium exchanger-3 occur downstream of Aβ in Alzheimer's disease. Aging Cell. 13: 49-59. PMID 23919677 DOI: 10.1111/Acel.12148 |
0.719 |
|
| 2014 |
Phillips EC, Garwood CJ, Hanger DP, Noble W. P1-116: ASTROCYTE ACTIVATION INFLUENCES THE DEVELOPMENT OF TAUOPATHY Alzheimer's & Dementia. 10: P343-P343. DOI: 10.1016/J.Jalz.2014.05.353 |
0.475 |
|
| 2014 |
Lau DH, Pooler AM, Noble W, Hanger DP. P1-115: IDENTIFICATION OF THE BINDING SITE BETWEEN TAU AND FYN: CONSEQUENCES FOR TAU RELEASE? Alzheimer's & Dementia. 10: P343-P343. DOI: 10.1016/J.Jalz.2014.05.352 |
0.728 |
|
| 2013 |
Noble W, Hanger DP, Miller CC, Lovestone S. The importance of tau phosphorylation for neurodegenerative diseases. Frontiers in Neurology. 4: 83. PMID 23847585 DOI: 10.3389/Fneur.2013.00083 |
0.758 |
|
| 2013 |
RodrÃguez-MartÃn T, Cuchillo-Ibáñez I, Noble W, Nyenya F, Anderton BH, Hanger DP. Tau phosphorylation affects its axonal transport and degradation. Neurobiology of Aging. 34: 2146-57. PMID 23601672 DOI: 10.1016/J.Neurobiolaging.2013.03.015 |
0.744 |
|
| 2013 |
Tavares IA, Touma D, Lynham S, Troakes C, Schober M, Causevic M, Garg R, Noble W, Killick R, Bodi I, Hanger DP, Morris JD. Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease. The Journal of Biological Chemistry. 288: 15418-29. PMID 23585562 DOI: 10.1074/Jbc.M112.448183 |
0.733 |
|
| 2013 |
Pooler AM, Phillips EC, Lau DH, Noble W, Hanger DP. Physiological release of endogenous tau is stimulated by neuronal activity. Embo Reports. 14: 389-94. PMID 23412472 DOI: 10.1038/Embor.2013.15 |
0.819 |
|
| 2013 |
Pooler A, Phillips E, Lau D, Noble W, Hanger D. O2-01-03: Neuronal activity regulates secretion of endogenous tau Alzheimer's & Dementia. 9: P314-P315. DOI: 10.1016/J.Jalz.2013.04.137 |
0.781 |
|
| 2012 |
Richet E, Pooler AM, Rodriguez T, Novoselov SS, Schmidtke G, Groettrup M, Hanger DP, Cheetham ME, van der Spuy J. NUB1 modulation of GSK3β reduces tau aggregation. Human Molecular Genetics. 21: 5254-67. PMID 22965877 DOI: 10.1093/hmg/dds376 |
0.807 |
|
| 2012 |
Gilley J, Seereeram A, Ando K, Mosely S, Andrews S, Kerschensteiner M, Misgeld T, Brion JP, Anderton B, Hanger DP, Coleman MP. Age-dependent axonal transport and locomotor changes and tau hypophosphorylation in a "P301L" tau knockin mouse. Neurobiology of Aging. 33: 621.e1-621.e15. PMID 21492964 DOI: 10.1016/J.Neurobiolaging.2011.02.014 |
0.48 |
|
| 2012 |
Pooler AM, Usardi A, Evans CJ, Philpott KL, Noble W, Hanger DP. Dynamic association of tau with neuronal membranes is regulated by phosphorylation. Neurobiology of Aging. 33: 431.e27-38. PMID 21388709 DOI: 10.1016/J.Neurobiolaging.2011.01.005 |
0.824 |
|
| 2011 |
Noble W, Pooler AM, Hanger DP. Advances in tau-based drug discovery. Expert Opinion On Drug Discovery. 6: 797-810. PMID 22003359 DOI: 10.1517/17460441.2011.586690 |
0.813 |
|
| 2011 |
Hanger DP, Noble W. Functional implications of glycogen synthase kinase-3-mediated tau phosphorylation. International Journal of Alzheimer's Disease. 2011: 352805. PMID 21776376 DOI: 10.4061/2011/352805 |
0.747 |
|
| 2011 |
Usardi A, Pooler AM, Seereeram A, Reynolds CH, Derkinderen P, Anderton B, Hanger DP, Noble W, Williamson R. Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau. The Febs Journal. 278: 2927-37. PMID 21692989 DOI: 10.1111/J.1742-4658.2011.08218.X |
0.837 |
|
| 2011 |
Garwood CJ, Pooler AM, Atherton J, Hanger DP, Noble W. Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture. Cell Death & Disease. 2: e167. PMID 21633390 DOI: 10.1038/Cddis.2011.50 |
0.801 |
|
| 2010 |
Garwood CJ, Cooper JD, Hanger DP, Noble W. Anti-inflammatory impact of minocycline in a mouse model of tauopathy. Frontiers in Psychiatry. 1: 136. PMID 21423446 DOI: 10.3389/Fpsyt.2010.00136 |
0.668 |
|
| 2010 |
Hanger DP, Wray S. Tau cleavage and tau aggregation in neurodegenerative disease. Biochemical Society Transactions. 38: 1016-20. PMID 20658996 DOI: 10.1042/Bst0381016 |
0.708 |
|
| 2010 |
Pooler AM, Hanger DP. Functional implications of the association of tau with the plasma membrane. Biochemical Society Transactions. 38: 1012-5. PMID 20658995 DOI: 10.1042/BST0381012 |
0.786 |
|
| 2010 |
Noble W, Hanger DP, Gallo JM. Transgenic mouse models of tauopathy in drug discovery. Cns & Neurological Disorders Drug Targets. 9: 403-28. PMID 20522014 DOI: 10.2174/187152710791556131 |
0.673 |
|
| 2010 |
Pooler AM, Usardi A, Hanger DP. P1-362: Dynamic association of tau with neuronal membranes is regulated by phosphorylation and the tyrosine kinase fyn Alzheimer's & Dementia. 6: S277-S278. DOI: 10.1016/j.jalz.2010.05.916 |
0.755 |
|
| 2010 |
Garwood CJ, Hanger DP, Noble W. P1-315: Minocycline-mediated protection from Aβ is mediated primarily by suppression of astrocytic inflammatory responses Alzheimer's & Dementia. 6: S264-S265. DOI: 10.1016/J.Jalz.2010.05.868 |
0.517 |
|
| 2010 |
Povellato G, Tuxworth R, Hanger D, Tear G. P1-164: A model system to investigate the phosphorylation events responsible for tau hyperphosphorylation in vivo Alzheimer's & Dementia. 6: S221-S221. DOI: 10.1016/J.Jalz.2010.05.714 |
0.487 |
|
| 2009 |
Hanger DP, Seereeram A, Noble W. Mediators of tau phosphorylation in the pathogenesis of Alzheimer's disease. Expert Review of Neurotherapeutics. 9: 1647-66. PMID 19903024 DOI: 10.1586/Ern.09.104 |
0.737 |
|
| 2009 |
Lebouvier T, Scales TM, Williamson R, Noble W, Duyckaerts C, Hanger DP, Reynolds CH, Anderton BH, Derkinderen P. The microtubule-associated protein tau is also phosphorylated on tyrosine. Journal of Alzheimer's Disease : Jad. 18: 1-9. PMID 19542604 DOI: 10.3233/Jad-2009-1116 |
0.703 |
|
| 2009 |
Thompson AJ, Williamson R, Schofield E, Stephenson J, Hanger D, Anderton B. Quantitation of glycogen synthase kinase-3 sensitive proteins in neuronal membrane rafts. Proteomics. 9: 3022-35. PMID 19526546 DOI: 10.1002/Pmic.200900006 |
0.398 |
|
| 2009 |
Noble W, Garwood CJ, Hanger DP. Minocycline as a potential therapeutic agent in neurodegenerative disorders characterised by protein misfolding. Prion. 3: 78-83. PMID 19458490 DOI: 10.4161/Pri.3.2.8820 |
0.538 |
|
| 2009 |
Hanger DP, Anderton BH, Noble W. Tau phosphorylation: the therapeutic challenge for neurodegenerative disease. Trends in Molecular Medicine. 15: 112-9. PMID 19246243 DOI: 10.1016/J.Molmed.2009.01.003 |
0.753 |
|
| 2009 |
Noble W, Garwood C, Stephenson J, Kinsey AM, Hanger DP, Anderton BH. Minocycline reduces the development of abnormal tau species in models of Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 739-50. PMID 19001528 DOI: 10.1096/Fj.08-113795 |
0.721 |
|
| 2009 |
Pooler AM, Hanger DP. P3-208: Phosphorylation-dependent association of tau with the neuronal membrane Alzheimer's & Dementia. 5: P404-P404. DOI: 10.1016/j.jalz.2009.04.981 |
0.756 |
|
| 2008 |
Cuchillo-Ibanez I, Seereeram A, Byers HL, Leung KY, Ward MA, Anderton BH, Hanger DP. Phosphorylation of tau regulates its axonal transport by controlling its binding to kinesin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3186-95. PMID 18511549 DOI: 10.1096/fj.08-109181 |
0.472 |
|
| 2008 |
Reynolds CH, Garwood CJ, Wray S, Price C, Kellie S, Perera T, Zvelebil M, Yang A, Sheppard PW, Varndell IM, Hanger DP, Anderton BH. Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases. The Journal of Biological Chemistry. 283: 18177-86. PMID 18467332 DOI: 10.1074/Jbc.M709715200 |
0.652 |
|
| 2008 |
Wray S, Saxton M, Anderton BH, Hanger DP. Direct analysis of tau from PSP brain identifies new phosphorylation sites and a major fragment of N-terminally cleaved tau containing four microtubule-binding repeats. Journal of Neurochemistry. 105: 2343-52. PMID 18315566 DOI: 10.1111/J.1471-4159.2008.05321.X |
0.67 |
|
| 2008 |
Williamson R, Usardi A, Hanger DP, Anderton BH. Membrane-bound beta-amyloid oligomers are recruited into lipid rafts by a fyn-dependent mechanism. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1552-9. PMID 18096814 DOI: 10.1096/fj.07-9766com |
0.348 |
|
| 2008 |
Lebouvier T, Scales TM, Hanger DP, Geahlen RL, Lardeux B, Reynolds CH, Anderton BH, Derkinderen P. The microtubule-associated protein tau is phosphorylated by Syk. Biochimica Et Biophysica Acta. 1783: 188-92. PMID 18070606 DOI: 10.1016/J.Bbamcr.2007.11.005 |
0.532 |
|
| 2008 |
Noble W, Garwood C, Hanger DP, Anderton BH. P3-342: Amyloid-mediated NCX3 cleavage by calpain is an early and toxic event Alzheimer's & Dementia. 4: T622-T622. DOI: 10.1016/J.Jalz.2008.05.1911 |
0.525 |
|
| 2008 |
Garwood CJ, Anderton BH, Hanger DP, Noble W. P2-381: Minocycline reduces caspase-3 activation and prevents cleavage and aggregation of Tau in vivo Alzheimer's & Dementia. 4: T484-T484. DOI: 10.1016/J.Jalz.2008.05.1459 |
0.593 |
|
| 2008 |
Schofield EL, Ward MA, Fernandez-Ocana M, Killick R, Hanger D, Byers HL, Lovestone S, Anderton B. P2-160: The use of mass spectrometry for multisite phosphorylation assays for tau protein Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1234 |
0.434 |
|
| 2008 |
Seereeram A, Siemann M, Anderton BH, Hanger DP. P2-149: The role of protein kinase A in coordinating tau phosphorylation state relevant to Alzheimer's disease Alzheimer's & Dementia. 4: T414-T414. DOI: 10.1016/j.jalz.2008.05.1222 |
0.458 |
|
| 2008 |
Wray S, Anderton BH, Hanger DP. P2-132: Potential toxicity of tau cleavage products in progressive supranuclear palsy Alzheimer's & Dementia. 4: T409-T409. DOI: 10.1016/J.Jalz.2008.05.1205 |
0.54 |
|
| 2007 |
Kelleher I, Garwood C, Hanger DP, Anderton BH, Noble W. Kinase activities increase during the development of tauopathy in htau mice. Journal of Neurochemistry. 103: 2256-67. PMID 17908241 DOI: 10.1111/J.1471-4159.2007.04930.X |
0.713 |
|
| 2007 |
Cole AR, Noble W, van Aalten L, Plattner F, Meimaridou R, Hogan D, Taylor M, LaFrancois J, Gunn-Moore F, Verkhratsky A, Oddo S, LaFerla F, Giese KP, Dineley KT, Duff K, ... ... Hanger DP, et al. Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression. Journal of Neurochemistry. 103: 1132-44. PMID 17683481 DOI: 10.1111/J.1471-4159.2007.04829.X |
0.707 |
|
| 2007 |
Hanger DP, Byers HL, Wray S, Leung KY, Saxton MJ, Seereeram A, Reynolds CH, Ward MA, Anderton BH. Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis. The Journal of Biological Chemistry. 282: 23645-54. PMID 17562708 DOI: 10.1074/Jbc.M703269200 |
0.635 |
|
| 2006 |
Seereeram A, Saxton M, Ward MA, Anderton BH, Hanger DP. P3-315: The role of glycogen synthase kinase -3β (GSK-3β) and cyclin-dependent kinase-5 (CDK5) in the generation of hyperphosphorylated tau relevant to Alzheimer's disease Alzheimer's & Dementia. 2: S467-S468. DOI: 10.1016/j.jalz.2006.05.1585 |
0.373 |
|
| 2006 |
Wray S, Revesz T, Holton JL, Anderton BH, Hanger DP. P3-309: Enrichment of insoluble tau from progressive supranuclear palsy brain tissue Alzheimer's & Dementia. 2: S466-S466. DOI: 10.1016/J.Jalz.2006.05.1579 |
0.535 |
|
| 2006 |
Noble W, Hanger DP, Anderton BH. O2-05-07: Minocycline reduces tau phosphorylation and protects against Aβ-induced neurotoxicity Alzheimer's & Dementia. 2: S41-S42. DOI: 10.1016/J.Jalz.2006.05.144 |
0.649 |
|
| 2005 |
Utton MA, Noble WJ, Hill JE, Anderton BH, Hanger DP. Molecular motors implicated in the axonal transport of tau and alpha-synuclein. Journal of Cell Science. 118: 4645-54. PMID 16176937 DOI: 10.1242/jcs.02558 |
0.578 |
|
| 2005 |
Derkinderen P, Scales TM, Hanger DP, Leung KY, Byers HL, Ward MA, Lenz C, Price C, Bird IN, Perera T, Kellie S, Williamson R, Noble W, Van Etten RA, Leroy K, et al. Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6584-93. PMID 16014719 DOI: 10.1523/Jneurosci.1487-05.2005 |
0.718 |
|
| 2005 |
Connell JW, Rodriguez-Martin T, Gibb GM, Kahn NM, Grierson AJ, Hanger DP, Revesz T, Lantos PL, Anderton BH, Gallo JM. Quantitative analysis of tau isoform transcripts in sporadic tauopathies. Brain Research. Molecular Brain Research. 137: 104-9. PMID 15950767 DOI: 10.1016/j.molbrainres.2005.02.014 |
0.311 |
|
| 2004 |
Totterdell S, Hanger D, Meredith GE. The ultrastructural distribution of alpha-synuclein-like protein in normal mouse brain. Brain Research. 1004: 61-72. PMID 15033420 DOI: 10.1016/J.Brainres.2003.10.072 |
0.428 |
|
| 2004 |
Gibb GM, de Silva R, Revesz T, Lees AJ, Anderton BH, Hanger DP. Differential involvement and heterogeneous phosphorylation of tau isoforms in progressive supranuclear palsy. Brain Research. Molecular Brain Research. 121: 95-101. PMID 14969740 DOI: 10.1016/J.Molbrainres.2003.11.007 |
0.552 |
|
| 2004 |
Noble WJ, Utton MA, Anderton BH, Hanger DP. P3-258 Molecular motors implicated in the fast axonal transport of tau Neurobiology of Aging. 25: S428. DOI: 10.1016/S0197-4580(04)81408-8 |
0.518 |
|
| 2003 |
de Silva R, Lashley T, Gibb G, Hanger D, Hope A, Reid A, Bandopadhyay R, Utton M, Strand C, Jowett T, Khan N, Anderton B, Wood N, Holton J, Revesz T, et al. Pathological inclusion bodies in tauopathies contain distinct complements of tau with three or four microtubule-binding repeat domains as demonstrated by new specific monoclonal antibodies. Neuropathology and Applied Neurobiology. 29: 288-302. PMID 12787326 DOI: 10.1046/J.1365-2990.2003.00463.X |
0.546 |
|
| 2003 |
Hanger D. S.03.02 Tau phosphorylation in Alzheimer's disease European Neuropsychopharmacology. 13: S100. DOI: 10.1016/S0924-977X(03)91606-3 |
0.448 |
|
| 2002 |
Hanger DP, Gibb GM, de Silva R, Boutajangout A, Brion JP, Revesz T, Lees AJ, Anderton BH. The complex relationship between soluble and insoluble tau in tauopathies revealed by efficient dephosphorylation and specific antibodies. Febs Letters. 531: 538-42. PMID 12435607 DOI: 10.1016/S0014-5793(02)03611-6 |
0.613 |
|
| 2002 |
Morris HR, Gibb G, Katzenschlager R, Wood NW, Hanger DP, Strand C, Lashley T, Daniel SE, Lees AJ, Anderton BH, Revesz T. Pathological, clinical and genetic heterogeneity in progressive supranuclear palsy. Brain : a Journal of Neurology. 125: 969-75. PMID 11960887 |
0.337 |
|
| 2002 |
Holton JL, Lashley T, Ghiso J, Braendgaard H, Vidal R, Guerin CJ, Gibb G, Hanger DP, Rostagno A, Anderton BH, Strand C, Ayling H, Plant G, Frangione B, Bojsen-Møller M, et al. Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta. Journal of Neuropathology and Experimental Neurology. 61: 254-67. PMID 11895040 DOI: 10.1093/Jnen/61.3.254 |
0.353 |
|
| 2002 |
Saha A, Hanger D, Anderton B. α-Synuclein and the Molecular Mechanisms of Lewy Body Formation in Parkinson's Disease Clinical Science. 103. DOI: 10.1042/Cs103002Pb |
0.319 |
|
| 2001 |
Anderton BH, Betts J, Blackstock WP, Brion JP, Chapman S, Connell J, Dayanandan R, Gallo JM, Gibb G, Hanger DP, Hutton M, Kardalinou E, Leroy K, Lovestone S, Mack T, et al. Sites of phosphorylation in tau and factors affecting their regulation. Biochemical Society Symposium. 73-80. PMID 11447841 DOI: 10.1042/Bst028A015B |
0.549 |
|
| 2000 |
Saha AR, Ninkina NN, Hanger DP, Anderton BH, Davies AM, Buchman VL. Induction of neuronal death by alpha-synuclein. The European Journal of Neuroscience. 12: 3073-7. PMID 10971650 DOI: 10.1046/J.1460-9568.2000.00210.X |
0.319 |
|
| 1998 |
Hanger DP, Betts JC, Loviny TL, Blackstock WP, Anderton BH. New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry. Journal of Neurochemistry. 71: 2465-76. PMID 9832145 |
0.557 |
|
| 1997 |
Cairns NJ, Atkinson PF, Hanger DP, Anderton BH, Daniel SE, Lantos PL. Tau protein in the glial cytoplasmic inclusions of multiple system atrophy can be distinguished from abnormal tau in Alzheimer's disease. Neuroscience Letters. 230: 49-52. PMID 9259461 DOI: 10.1016/S0304-3940(97)00474-6 |
0.555 |
|
| 1997 |
Davis DR, Anderton BH, Brion JP, Reynolds CH, Hanger DP. Oxidative stress induces dephosphorylation of tau in rat brain primary neuronal cultures. Journal of Neurochemistry. 68: 1590-7. PMID 9084430 |
0.463 |
|
| 1996 |
Fergusson J, Landon M, Lowe J, Dawson SP, Layfield R, Hanger DP, Mayer RJ. Pathological lesions of Alzheimer's disease and dementia with Lewy bodies brains exhibit immunoreactivity to an ATPase that is a regulatory subunit of the 26S proteasome. Neuroscience Letters. 219: 167-70. PMID 8971806 DOI: 10.1016/S0304-3940(96)13192-X |
0.342 |
|
| 1996 |
James ND, Davis DR, Sindon J, Hanger DP, Brion JP, Miller CC, Rosenberg MP, Anderton BH, Propst F. Neurodegenerative changes including altered tau phosphorylation and neurofilament immunoreactivity in mice transgenic for the serine/threonine kinase Mos. Neurobiology of Aging. 17: 235-41. PMID 8744404 DOI: 10.1016/0197-4580(95)02068-3 |
0.502 |
|
| 1995 |
Mulot SF, Hughes K, Woodgett JR, Anderton BH, Hanger DP. Phosphorylation of tau by glycogen synthase kinase-3 beta in vitro produces species with similar electrophoretic and immunogenic properties to PHF-tau from Alzheimer's disease brain. Biochemical Society Transactions. 23: 45S. PMID 7758758 DOI: 10.1042/Bst023045S |
0.478 |
|
| 1995 |
Davis DR, Brion JP, Couck AM, Gallo JM, Hanger DP, Ladhani K, Lewis C, Miller CC, Rupniak T, Smith C. The phosphorylation state of the microtubule-associated protein tau as affected by glutamate, colchicine and beta-amyloid in primary rat cortical neuronal cultures. The Biochemical Journal. 309: 941-9. PMID 7639714 DOI: 10.1042/Bj3090941 |
0.494 |
|
| 1995 |
Anderton BH, Brion JP, Couck AM, Davis DR, Gallo JM, Hanger DP, Ladhani K, Latimer DA, Lewis C, Lovestone S. Modulation of PHF-like tau phosphorylation in cultured neurones and transfected cells. Neurobiology of Aging. 16: 389-97; discussion 3. PMID 7566348 DOI: 10.1016/0197-4580(94)00160-3 |
0.537 |
|
| 1995 |
Anderton BH, Brion JP, Davis DR, Gallo JM, Hanger D, Latimer D, Lovestone S, Miller CCJ, Mulot S, Reynolds CH. Cytoskeletal pathology Journal of Neuropathology and Experimental Neurology. 54: 4S-5S. |
0.367 |
|
| 1994 |
Mulot SF, Hughes K, Woodgett JR, Anderton BH, Hanger DP. PHF-tau from Alzheimer's brain comprises four species on SDS-PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase-3 beta. Febs Letters. 349: 359-64. PMID 8050597 DOI: 10.1016/0014-5793(94)00702-0 |
0.397 |
|
| 1994 |
Lovestone S, Reynolds CH, Latimer D, Davis DR, Anderton BH, Gallo JM, Hanger D, Mulot S, Marquardt B, Stabel S. Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. Current Biology : Cb. 4: 1077-86. PMID 7704571 DOI: 10.1016/S0960-9822(00)00246-3 |
0.606 |
|
| 1993 |
Robertson J, Loviny TL, Goedert M, Jakes R, Murray KJ, Anderton BH, Hanger DP. Phosphorylation of tau by cyclic-AMP-dependent protein kinase. Dementia (Basel, Switzerland). 4: 256-63. PMID 8261023 DOI: 10.1159/000107331 |
0.522 |
|
| 1992 |
Lantos PL, Luthert PJ, Hanger D, Anderton BH, Mullan M, Rossor M. Familial Alzheimer's disease with the amyloid precursor protein position 717 mutation and sporadic Alzheimer's disease have the same cytoskeletal pathology. Neuroscience Letters. 137: 221-4. PMID 1584463 DOI: 10.1016/0304-3940(92)90408-Y |
0.498 |
|
| 1992 |
Gallo JM, Hanger DP, Twist EC, Kosik KS, Anderton BH. Expression and phosphorylation of a three-repeat isoform of tau in transfected non-neuronal cells. The Biochemical Journal. 286: 399-404. PMID 1530572 |
0.422 |
|
| 1992 |
Hanger DP, Mann DM, Neary D, Anderton BH. Tau pathology in a case of familial Alzheimer's disease with a valine to glycine mutation at position 717 in the amyloid precursor protein. Neuroscience Letters. 145: 178-80. PMID 1465214 DOI: 10.1016/0304-3940(92)90016-Z |
0.475 |
|
| 1992 |
Hanger DP, Mann DM, Neary D, Anderton BH. Molecular pathology of Alzheimer's disease in sporadic and familial Alzheimer's disease with mutations in the amyloid precursor protein. Biochemical Society Transactions. 20: 642-5. PMID 1426605 DOI: 10.1042/Bst0200642 |
0.326 |
|
| 1992 |
Hanger DP, Hughes K, Woodgett JR, Brion JP, Anderton BH. Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase. Neuroscience Letters. 147: 58-62. PMID 1336152 DOI: 10.1016/0304-3940(92)90774-2 |
0.556 |
|
| 1992 |
Anderton B, Hanger D, Lantos P, Mullan M, Rossor M, Luthert P. Familial Alzheimer's disease with an APP717 point mutation and sporadic Alzheimer's disease have the same cytoskeletal pathology Neurobiology of Aging. 13: S57. DOI: 10.1016/0197-4580(92)90352-X |
0.412 |
|
| 1992 |
Hanger D, Loviny T, Robertson J, Goedert M, Murray K, Anderton B. Cyclic AMP-dependent protein kinase induces a shift in the electrophoretic mobility of human tau Neurobiology of Aging. 13: S54. DOI: 10.1016/0197-4580(92)90339-Y |
0.353 |
|
| 1991 |
Brion JP, Hanger DP, Couck AM, Anderton BH. A68 proteins in Alzheimer's disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities. The Biochemical Journal. 279: 831-6. PMID 1953678 DOI: 10.1042/Bj2790831 |
0.475 |
|
| 1991 |
Brion JP, Hanger DP, Bruce MT, Couck AM, Flament-Durand J, Anderton BH. Tau in Alzheimer neurofibrillary tangles. N- and C-terminal regions are differentially associated with paired helical filaments and the location of a putative abnormal phosphorylation site. The Biochemical Journal. 273: 127-33. PMID 1899184 |
0.475 |
|
| 1991 |
Hanger DP, Brion JP, Gallo JM, Cairns NJ, Luthert PJ, Anderton BH. Tau in Alzheimer's disease and Down's syndrome is insoluble and abnormally phosphorylated. The Biochemical Journal. 275: 99-104. PMID 1826835 DOI: 10.1042/Bj2750099 |
0.573 |
|
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