Year |
Citation |
Score |
2013 |
Zhao P, Chen SK, Cai YH, Lu X, Li Z, Cheng YK, Zhang C, Hu X, He X, Luo HB. The molecular basis for the inhibition of phosphodiesterase-4D by three natural resveratrol analogs. Isolation, molecular docking, molecular dynamics simulations, binding free energy, and bioassay. Biochimica Et Biophysica Acta. 1834: 2089-96. PMID 23871879 DOI: 10.1016/J.Bbapap.2013.07.004 |
0.668 |
|
2013 |
Li Z, Cai YH, Cheng YK, Lu X, Shao YX, Li X, Liu M, Liu P, Luo HB. Identification of novel phosphodiesterase-4D inhibitors prescreened by molecular dynamics-augmented modeling and validated by bioassay. Journal of Chemical Information and Modeling. 53: 972-81. PMID 23517293 DOI: 10.1021/ci400063s |
0.649 |
|
2011 |
Liu M, Yuan M, Li Z, Cheng YK, Luo HB, Hu X. Structural investigation into the inhibitory mechanisms of indomethacin and its analogues towards human glyoxalase I. Bioorganic & Medicinal Chemistry Letters. 21: 4243-7. PMID 21689932 DOI: 10.1016/J.Bmcl.2011.05.095 |
0.665 |
|
2007 |
Luo HB, Zheng C, Cheng YK. Is phospholipid-saturated alkyl column a convenient replacement for immobilized-artificial-membrane? Journal of Chromatography. A. 1176: 100-6. PMID 18022632 DOI: 10.1016/J.Chroma.2007.10.093 |
0.654 |
|
2007 |
Leng X, Choi CF, Luo HB, Cheng YK, Ng DK. Host-guest interactions of 4-carboxyphenoxy phthalocyanines and beta-cyclodextrins in aqueous media. Organic Letters. 9: 2497-500. PMID 17536811 DOI: 10.1021/Ol070888X |
0.608 |
|
2007 |
Leung KW, Yung KK, Mak NK, Yue PY, Luo HB, Cheng YK, Fan TP, Yeung HW, Ng TB, Wong RN. Angiomodulatory and neurological effects of ginsenosides. Current Medicinal Chemistry. 14: 1371-80. PMID 17504218 DOI: 10.2174/092986707780597916 |
0.647 |
|
2007 |
Luo HB, Zheng C, Cheng YK. Complex retention behavior of pyrimidines on biomembrane-mimic immobilized-artificial-membrane phase. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 853: 114-22. PMID 17400526 DOI: 10.1016/J.Jchromb.2007.02.059 |
0.669 |
|
2007 |
Chan W, Luo HB, Zheng Y, Cheng YK, Cai Z. Investigation of the metabolism and reductive activation of carcinogenic aristolochic acids in rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 866-74. PMID 17344338 DOI: 10.1124/Dmd.106.013979 |
0.61 |
|
2007 |
Sun XH, Li W, Xia PF, Luo HB, Wei Y, Wong MS, Cheng YK, Shuang S. Phenyl-calix[4]arene-based fluorescent sensors: cooperative binding for carboxylates. The Journal of Organic Chemistry. 72: 2419-26. PMID 17343417 DOI: 10.1021/Jo062258Z |
0.649 |
|
2007 |
Luo H, Zheng C, Cheng YK. The retention properties of nucleobases in alkyl C8-/C18- and IAM-chromatographic systems in relation to log Pow. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 847: 245-61. PMID 17070738 DOI: 10.1016/J.Jchromb.2006.10.009 |
0.674 |
|
2006 |
Luo H, Cheng YK. A comparative study of void volume markers in immobilized-artificial-membrane and reversed-phase liquid chromatography. Journal of Chromatography. A. 1103: 356-61. PMID 16387316 DOI: 10.1016/J.Chroma.2005.12.036 |
0.662 |
|
Low-probability matches (unlikely to be authored by this person) |
2009 |
Liu M, Yuan M, Luo M, Bu X, Luo HB, Hu X. Binding of curcumin with glyoxalase I: Molecular docking, molecular dynamics simulations, and kinetics analysis. Biophysical Chemistry. 147: 28-34. PMID 20071071 DOI: 10.1016/j.bpc.2009.12.007 |
0.294 |
|
2015 |
Huang M, Shao Y, Hou J, Cai W, Liang B, Huang Y, Li Z, Wu Y, Zhu X, Liu P, Wan Y, Ke H, Luo HB. Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor. Molecular Pharmacology. PMID 26316540 DOI: 10.1124/Mol.115.099747 |
0.288 |
|
2018 |
Zheng X, Jiang Z, Li X, Zhang C, Li Z, Wu Y, Wang X, Zhang C, Luo HB, Xu J, Wu D. Screening, synthesis, crystal structure, and molecular basis of 6-amino-4-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles as novel AKR1C3 inhibitors. Bioorganic & Medicinal Chemistry. PMID 30429100 DOI: 10.1016/j.bmc.2018.10.044 |
0.283 |
|
2012 |
Mo SL, Liu WF, Chen Y, Luo HB, Sun LB, Chen XW, Zhou ZW, Sneed KB, Li CG, Du YM, Liang J, Zhou SF. Ligand- and protein-based modeling studies of the inhibitors of human cytochrome P450 2D6 and a virtual screening for potential inhibitors from the Chinese herbal medicine, Scutellaria baicalensis (Huangqin,Baikal Skullcap). Combinatorial Chemistry & High Throughput Screening. 15: 36-80. PMID 21846324 |
0.259 |
|
2012 |
Chen SK, Zhao P, Shao YX, Li Z, Zhang C, Liu P, He X, Luo HB, Hu X. Moracin M from Morus alba L. is a natural phosphodiesterase-4 inhibitor. Bioorganic & Medicinal Chemistry Letters. 22: 3261-4. PMID 22483586 DOI: 10.1016/j.bmcl.2012.03.026 |
0.252 |
|
2015 |
Li Z, Lu X, Feng LJ, Gu Y, Li X, Wu Y, Luo HB. Molecular dynamics-based discovery of novel phosphodiesterase-9A inhibitors with non-pyrazolopyrimidinone scaffolds. Molecular Biosystems. 11: 115-25. PMID 25328054 DOI: 10.1039/c4mb00389f |
0.251 |
|
2013 |
Huang YY, Li Z, Cai YH, Feng LJ, Wu Y, Li X, Luo HB. The molecular basis for the selectivity of tadalafil toward phosphodiesterase 5 and 6: a modeling study. Journal of Chemical Information and Modeling. 53: 3044-53. PMID 24180640 DOI: 10.1021/ci400458z |
0.246 |
|
2010 |
He L, He F, Bi H, Li J, Zeng S, Luo HB, Huang M. Isoform-selective inhibition of chrysin towards human cytochrome P450 1A2. Kinetics analysis, molecular docking, and molecular dynamics simulations. Bioorganic & Medicinal Chemistry Letters. 20: 6008-12. PMID 20832301 DOI: 10.1016/j.bmcl.2010.08.072 |
0.246 |
|
2010 |
Liu M, He L, Hu X, Liu P, Luo HB. 3D-QSAR, homology modeling, and molecular docking studies on spiropiperidines analogues as agonists of nociceptin/orphanin FQ receptor. Bioorganic & Medicinal Chemistry Letters. 20: 7004-10. PMID 20961754 DOI: 10.1016/j.bmcl.2010.09.116 |
0.244 |
|
2021 |
Wu D, Zheng X, Liu R, Li Z, Jiang Z, Zhou Q, Huang Y, Wu XN, Zhang C, Huang YY, Luo HB. Free energy perturbation (FEP)-guided scaffold hopping. Acta Pharmaceutica Sinica. B. 12: 1351-1362. PMID 35530128 DOI: 10.1016/j.apsb.2021.09.027 |
0.242 |
|
2012 |
Shao YX, Zhao P, Li Z, Liu M, Liu P, Huang M, Luo HB. The molecular basis for the inhibition of human cytochrome P450 1A2 by oroxylin and wogonin. European Biophysics Journal : Ebj. 41: 297-306. PMID 22228220 DOI: 10.1007/s00249-011-0785-1 |
0.235 |
|
2013 |
Mo SL, Liu WF, Li CG, Zhou ZW, Luo HB, Chew H, Liang J, Zhou SF. Pharmacophore, QSAR, and binding mode studies of substrates of human cytochrome P450 2D6 (CYP2D6) using molecular docking and virtual mutations and an application to chinese herbal medicine screening. Current Pharmaceutical Biotechnology. 13: 1640-704. PMID 22039821 DOI: 10.2174/138920112800958779 |
0.232 |
|
2017 |
Qiu X, Huang Y, Wu D, Mao F, Zhu J, Yan W, Luo HB, Li J. Discovery of novel purine nucleoside derivatives as phosphodiesterase 2 (PDE2) inhibitors: Structure-based virtual screening, optimization and biological evaluation. Bioorganic & Medicinal Chemistry. PMID 29174506 DOI: 10.1016/j.bmc.2017.11.022 |
0.23 |
|
2010 |
Luo HB, Zheng H, Zimmerman MD, Chruszcz M, Skarina T, Egorova O, Savchenko A, Edwards AM, Minor W. Crystal structure and molecular modeling study of N-carbamoylsarcosine amidase Ta0454 from Thermoplasma acidophilum. Journal of Structural Biology. 169: 304-11. PMID 19932181 DOI: 10.1016/J.Jsb.2009.11.008 |
0.226 |
|
2014 |
Shang NN, Shao YX, Cai YH, Guan M, Huang M, Cui W, He L, Yu YJ, Huang L, Li Z, Bu XZ, Ke H, Luo HB. Discovery of 3-(4-hydroxybenzyl)-1-(thiophen-2-yl)chromeno[2,3-c]pyrrol-9(2H)-one as a phosphodiesterase-5 inhibitor and its complex crystal structure. Biochemical Pharmacology. 89: 86-98. PMID 24565909 DOI: 10.1016/J.Bcp.2014.02.013 |
0.225 |
|
2017 |
Zhang C, Feng LJ, Huang Y, Wu D, Li Z, Zhou Q, Wu Y, Luo HB. Discovery of Novel Phosphodiesterase-2A Inhibitors by Structure-based Virtual Screening, Structural Optimization, and Bioassay. Journal of Chemical Information and Modeling. PMID 28055196 DOI: 10.1021/acs.jcim.6b00551 |
0.224 |
|
2011 |
Hou JQ, Tan JH, Wang XX, Chen SB, Huang SY, Yan JW, Chen SH, Ou TM, Luo HB, Li D, Gu LQ, Huang ZS. Impact of planarity of unfused aromatic molecules on G-quadruplex binding: learning from isaindigotone derivatives. Organic & Biomolecular Chemistry. 9: 6422-36. PMID 21808792 DOI: 10.1039/c1ob05884c |
0.219 |
|
2017 |
Huang Y, Liu X, Wu D, Tang G, Lai Z, Zheng X, Sheng Y, Luo HB. The discovery, complex crystal structure, and recognition mechanism of a novel natural PDE4 inhibitor from Selaginella pulvinata. Biochemical Pharmacology. PMID 28159622 DOI: 10.1016/j.bcp.2017.01.016 |
0.218 |
|
2022 |
Wu XN, Zhou Q, Huang YD, Xie X, Li Z, Wu Y, Luo HB. Structure-based discovery of orally efficient inhibitors unique interactions with H-pocket of PDE8 for the treatment of vascular dementia. Acta Pharmaceutica Sinica. B. 12: 3103-3112. PMID 35865094 DOI: 10.1016/j.apsb.2022.02.012 |
0.218 |
|
2011 |
Hou J, Xu J, Liu M, Zhao R, Luo HB, Ke H. Structural asymmetry of phosphodiesterase-9, potential protonation of a glutamic acid, and role of the invariant glutamine. Plos One. 6: e18092. PMID 21483814 DOI: 10.1371/Journal.Pone.0018092 |
0.217 |
|
2006 |
Ye F, Zhang ZS, Luo HB, Shen JH, Chen KX, Shen X, Jiang HL. The dipeptide H-Trp-Glu-OH shows highly antagonistic activity against PPARgamma: bioassay with molecular modeling simulation. Chembiochem : a European Journal of Chemical Biology. 7: 74-82. PMID 16317783 DOI: 10.1002/cbic.200500186 |
0.216 |
|
2019 |
Li Z, Huang Y, Wu Y, Chen JY, Wu D, Zhan CG, Luo HB. Absolute binding free energy calculation and design of a subnanomolar inhibitor of phosphodiesterase-10. Journal of Medicinal Chemistry. PMID 30689375 DOI: 10.1021/acs.jmedchem.8b01763 |
0.214 |
|
2017 |
Yu YF, Huang YD, Zhang C, Wu XN, Zhou Q, Wu D, Wu Y, Luo HB. Discovery of novel pyrazolopyrimidinone derivatives as PDE9A inhibitors capable of inhibiting BuChE for treatment of Alzheimer's disease. Acs Chemical Neuroscience. PMID 28783948 DOI: 10.1021/acschemneuro.7b00268 |
0.213 |
|
2020 |
Zhang T, Lai Z, Yuan S, Huang YY, Dong G, Sheng C, Ke H, Luo HB. Discovery of Evodiamine Derivatives as Highly Selective PDE5 Inhibitors Targeting a Unique Allosteric Pocket. Journal of Medicinal Chemistry. PMID 32794708 DOI: 10.1021/Acs.Jmedchem.0C00983 |
0.212 |
|
2008 |
Li JK, He F, Bi HC, Zuo Z, Liu BD, Luo HB, Huang M. [Inhibition of human cytochrome P-450 CYP1A2 by flavonoids: a quantitative structure-activity relationship study ]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 43: 1198-204. PMID 19244749 |
0.212 |
|
2005 |
Yue L, Ye F, Gui C, Luo H, Cai J, Shen J, Chen K, Shen X, Jiang H. Ligand-binding regulation of LXR/RXR and LXR/PPAR heterodimerizations: SPR technology-based kinetic analysis correlated with molecular dynamics simulation. Protein Science : a Publication of the Protein Society. 14: 812-22. PMID 15722453 DOI: 10.1110/ps.04951405 |
0.211 |
|
2012 |
Zheng XH, Shao YX, Li Z, Liu M, Bu X, Luo HB, Hu X. Quantitative structure-retention relationship of curcumin and its analogues. Journal of Separation Science. 35: 505-12. PMID 22282411 DOI: 10.1002/jssc.201100903 |
0.209 |
|
2020 |
Yu YF, Zhang C, Huang YY, Zhang S, Zhou Q, Li X, Lai Z, Li Z, Gao Y, Wu Y, Guo L, Wu D, Luo HB. Discovery and Optimization of Chromone Derivatives as Novel Selective Phosphodiesterase 10 Inhibitors. Acs Chemical Neuroscience. PMID 32105440 DOI: 10.1021/acschemneuro.0c00024 |
0.205 |
|
2016 |
Zheng X, Wu Y, Wu D, Wang X, Zhang C, Guo X, Luo HB. 3D-QSAR studies of 3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic acids as AKR1C3 inhibitors: Highlight the importance of molecular docking in conformation generation. Bioorganic & Medicinal Chemistry Letters. PMID 27847272 DOI: 10.1016/j.bmcl.2016.10.073 |
0.201 |
|
2018 |
Wu XN, Huang YD, Li JX, Yu YF, Qian Z, Zhang C, Wu Y, Luo HB. Structure-based design, synthesis, and biological evaluation of novel pyrimidinone derivatives as PDE9 inhibitors. Acta Pharmaceutica Sinica. B. 8: 615-628. PMID 30109185 DOI: 10.1016/j.apsb.2017.12.007 |
0.201 |
|
2005 |
Chen L, Gui C, Luo X, Yang Q, Günther S, Scandella E, Drosten C, Bai D, He X, Ludewig B, Chen J, Luo H, Yang Y, Yang Y, Zou J, et al. Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro. Journal of Virology. 79: 7095-103. PMID 15890949 DOI: 10.1128/JVI.79.11.7095-7103.2005 |
0.2 |
|
2014 |
Li Z, Wu Y, Feng LJ, Wu R, Luo HB. Ab Initio QM/MM Study Shows a Highly Dissociated SN2 Hydrolysis Mechanism for the cGMP-Specific Phosphodiesterase-5. Journal of Chemical Theory and Computation. 10: 5448-57. PMID 26583228 DOI: 10.1021/ct500761d |
0.2 |
|
2012 |
Hou JQ, Chen SB, Tan JH, Luo HB, Li D, Gu LQ, Huang ZS. New insights from molecular dynamic simulation studies of the multiple binding modes of a ligand with G-quadruplex DNA. Journal of Computer-Aided Molecular Design. 26: 1355-68. PMID 23239169 DOI: 10.1007/s10822-012-9619-1 |
0.197 |
|
2010 |
Hou JQ, Chen SB, Tan JH, Ou TM, Luo HB, Li D, Xu J, Gu LQ, Huang ZS. New insights into the structures of ligand-quadruplex complexes from molecular dynamics simulations. The Journal of Physical Chemistry. B. 114: 15301-10. PMID 21049896 DOI: 10.1021/jp106683n |
0.197 |
|
2021 |
Zhang B, Huang Y, Zhang SR, Huang MX, Zhang C, Luo HB. Design, synthesis and biological evaluation of novel pyrazolopyrimidone derivatives as potent PDE1 inhibitors. Bioorganic Chemistry. 114: 105104. PMID 34186466 DOI: 10.1016/j.bioorg.2021.105104 |
0.196 |
|
2012 |
Meng F, Hou J, Shao YX, Wu PY, Huang M, Zhu X, Cai Y, Li Z, Xu J, Liu P, Luo HB, Wan Y, Ke H. Structure-based discovery of highly selective phosphodiesterase-9A inhibitors and implications for inhibitor design. Journal of Medicinal Chemistry. 55: 8549-58. PMID 22985069 DOI: 10.1021/Jm301189C |
0.193 |
|
2021 |
Li Z, Liu R, Zhan CG, Wang X, Luo HB. Reply to Behnam and Klein: Potential role of the His-tag in C-terminal His-tagged SARS-CoV-2 main protease. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34475220 DOI: 10.1073/pnas.2108209118 |
0.192 |
|
2023 |
Liu R, Li W, Yao Y, Wu Y, Luo HB, Li Z. Accelerating and Automating the Free Energy Perturbation Absolute Binding Free Energy Calculation with the RED-E Function. Journal of Chemical Information and Modeling. PMID 38048439 DOI: 10.1021/acs.jcim.3c01670 |
0.191 |
|
2004 |
Luo C, Luo H, Zheng S, Gui C, Yue L, Yu C, Sun T, He P, Chen J, Shen J, Luo X, Li Y, Liu H, Bai D, Shen J, et al. Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A. Biochemical and Biophysical Research Communications. 321: 557-65. PMID 15358143 DOI: 10.1016/j.bbrc.2004.07.003 |
0.191 |
|
2020 |
Yang Y, Zhang S, Zhou Q, Zhang C, Gao Y, Wang H, Li Z, Wu D, Wu Y, Huang YY, Guo L, Luo HB. Discovery of highly selective and orally available benzimidazole-based phosphodiesterase 10 inhibitors with improved solubility and pharmacokinetic properties for treatment of pulmonary arterial hypertension. Acta Pharmaceutica Sinica. B. 10: 2339-2347. PMID 33354505 DOI: 10.1016/j.apsb.2020.04.003 |
0.188 |
|
2021 |
Zhou Y, Li J, Yuan H, Su R, Huang Y, Huang Y, Li Z, Wu Y, Luo H, Zhang C, Huang L. Design, Synthesis, and Evaluation of Dihydropyranopyrazole Derivatives as Novel PDE2 Inhibitors for the Treatment of Alzheimer's Disease. Molecules (Basel, Switzerland). 26. PMID 34069639 DOI: 10.3390/molecules26103034 |
0.186 |
|
2005 |
Chen S, Chen LL, Luo HB, Sun T, Chen J, Ye F, Cai JH, Shen JK, Shen X, Jiang HL. Enzymatic activity characterization of SARS coronavirus 3C-like protease by fluorescence resonance energy transfer technique Acta Pharmacologica Sinica. 26: 99-106. PMID 15659121 DOI: 10.1111/j.1745-7254.2005.00010.x |
0.186 |
|
2006 |
Luo H, Chen J, Chen K, Shen X, Jiang H. Carboxyl terminus of severe acute respiratory syndrome coronavirus nucleocapsid protein: self-association analysis and nucleic acid binding characterization. Biochemistry. 45: 11827-35. PMID 17002283 DOI: 10.1021/bi0609319 |
0.184 |
|
2012 |
Zheng X, Zhang L, Zhai J, Chen Y, Luo H, Hu X. The molecular basis for inhibition of sulindac and its metabolites towards human aldose reductase. Febs Letters. 586: 55-9. PMID 22155003 DOI: 10.1016/j.febslet.2011.11.023 |
0.184 |
|
2020 |
Zhang P, Jiang MY, Le ML, Zhang B, Zhou Q, Wu Y, Zhang C, Luo HB. Design, synthesis and evaluation of pyrazolopyrimidinone derivatives as novel PDE9A inhibitors for treatment of Alzheimer's disease. Bioorganic & Medicinal Chemistry Letters. 30: 127254. PMID 32527553 DOI: 10.1016/j.bmcl.2020.127254 |
0.183 |
|
2023 |
Liu H, Yao Z, Sun M, Zhang C, Huang YY, Luo HB, Wu D, Zheng X. Inhibition of AKR1Cs by liquiritigenin and the structural basis. Chemico-Biological Interactions. 110654. PMID 37666442 DOI: 10.1016/j.cbi.2023.110654 |
0.182 |
|
2011 |
Lu SY, Jiang YJ, Zou JW, Luo HB, Wu TX. Insight into analysis of interactions of GW9508 to wild-type and H86F and H137F GPR40: a combined QM/MM study and pharmacophore modeling. Journal of Molecular Graphics & Modelling. 29: 818-25. PMID 21334233 DOI: 10.1016/j.jmgm.2011.01.006 |
0.181 |
|
2018 |
Zhang C, Zhou Q, Wu XN, Huang YS, Zhou J, Lai Z, Wu Y, Luo HB. Discovery of novel PDE9A inhibitors with antioxidant activities for treatment of Alzheimer's disease. Journal of Enzyme Inhibition and Medicinal Chemistry. 33: 260-270. PMID 29271265 DOI: 10.1080/14756366.2017.1412315 |
0.181 |
|
2014 |
Liu YN, Huang YY, Bao JM, Cai YH, Guo YQ, Liu SN, Luo HB, Yin S. Natural phosphodiesterase-4 (PDE4) inhibitors from Crotalaria ferruginea. Fitoterapia. 94: 177-82. PMID 24594242 DOI: 10.1016/j.fitote.2014.02.010 |
0.179 |
|
2020 |
Huang Y, Wu XN, Zhou Q, Wu Y, Zheng D, Li Z, Guo L, Luo HB. Rational Design of 2-Chloroadenine Derivatives as Highly Selective Phosphodiesterase 8A Inhibitors. Journal of Medicinal Chemistry. PMID 33291877 DOI: 10.1021/acs.jmedchem.0c01573 |
0.178 |
|
2018 |
Wu D, Huang Y, Chen Y, Huang YY, Geng H, Zhang T, Zhang C, Li Z, Guo L, Chen J, Luo HB. Optimization of Chromeno[2,3-c]pyrrol-9(2H)-ones as Highly Potent, Selective, and Orally Bioavailable PDE5 Inhibitors: Structure-Activity Relationship, X-ray Crystal Structure, and Pharmacodynamic Effect on Pulmonary Arterial Hypertension. Journal of Medicinal Chemistry. PMID 30148362 DOI: 10.1021/acs.jmedchem.8b01209 |
0.178 |
|
2017 |
Zheng X, Zhou S, Zhang C, Wu D, Luo HB, Wu Y. Docking-assisted 3D-QSAR studies on xanthones as α-glucosidase inhibitors. Journal of Molecular Modeling. 23: 272. PMID 28861624 DOI: 10.1007/s00894-017-3438-1 |
0.177 |
|
2019 |
Du Q, Damschroder M, Pabst TM, Hunter AK, Wang WK, Luo H. Process optimization and protein engineering mitigated manufacturing challenges of a monoclonal antibody with liquid-liquid phase separation issue by disrupting inter-molecule electrostatic interactions. Mabs. PMID 30913985 DOI: 10.1080/19420862.2019.1599634 |
0.176 |
|
2022 |
Song Z, Huang YY, Hou KQ, Liu L, Zhou F, Huang Y, Wan G, Luo HB, Xiong XF. Discovery and Structural Optimization of Toddacoumalone Derivatives as Novel PDE4 Inhibitors for the Topical Treatment of Psoriasis. Journal of Medicinal Chemistry. PMID 35188767 DOI: 10.1021/acs.jmedchem.1c02058 |
0.174 |
|
2023 |
Li Y, Shi J, Liu R, Liu Y, Liu R, Wu Z, Xu W, Ma H, Luo HB, Cheng Z. Structure Revisions of Phenolic Bisabolane Sesquiterpenes and a Ferroptosis Inhibitor from the Marine-Derived Fungus YPH93. Journal of Natural Products. PMID 36897077 DOI: 10.1021/acs.jnatprod.2c01022 |
0.174 |
|
2009 |
Luo H, Laksanalamai P, Robb FT. An exceptionally stable Group II chaperonin from the hyperthermophile Pyrococcus furiosus. Archives of Biochemistry and Biophysics. 486: 12-8. PMID 19298788 DOI: 10.1016/J.Abb.2009.03.005 |
0.172 |
|
2019 |
Zhang CX, Wei X, Feng C, Li XH, Mao XX, Luo HB, Zhang DM, Rong L, Xie ZY, Yu X, Li J, Ye WC, Huang XJ. New Enantiomeric Polyketides from the Starfish-Derived Symbiotic Fungus Penicillium sp. GGF16-1-2. Chemistry & Biodiversity. PMID 30946516 DOI: 10.1002/Cbdv.201900052 |
0.171 |
|
2021 |
Gao Y, Huang J, Zhou Q, Liu R, Zhang S, Zhang C, Huang YY, Li Z, Huang L, Wu D, Wu Y, Xiao L, Guo L, Luo HB. Discovery of Highly Specific Catalytic-Site-Targeting Fluorescent Probes for Detecting Lysosomal PDE10A in Living Cells. Acs Chemical Biology. PMID 33955736 DOI: 10.1021/acschembio.1c00018 |
0.17 |
|
2023 |
Li X, Yin W, Lin JD, Zhang Y, Guo Q, Wang G, Chen X, Cui B, Wang M, Chen M, Li P, He YW, Qian W, Luo H, Zhang LH, et al. Regulation of the physiology and virulence of Ralstonia solanacearum by the second messenger 2',3'-cyclic guanosine monophosphate. Nature Communications. 14: 7654. PMID 37996405 DOI: 10.1038/s41467-023-43461-2 |
0.168 |
|
2009 |
Yan J, Zhang C, Gu M, Bai Z, Zhang W, Qi T, Cheng Z, Peng W, Luo H, Nan F, Wang Z, Xie D. The Arabidopsis CORONATINE INSENSITIVE1 protein is a jasmonate receptor. The Plant Cell. 21: 2220-36. PMID 19717617 DOI: 10.1105/tpc.109.065730 |
0.167 |
|
2014 |
Zhou J, Xie H, Liu Z, Luo HB, Wu R. Structure-function analysis of the conserved tyrosine and diverse π-stacking among class I histone deacetylases: a QM (DFT)/MM MD study. Journal of Chemical Information and Modeling. 54: 3162-71. PMID 25360823 DOI: 10.1021/ci500513n |
0.166 |
|
2013 |
Li YP, Weng X, Ning FX, Ou JB, Hou JQ, Luo HB, Li D, Huang ZS, Huang SL, Gu LQ. 3D-QSAR studies of azaoxoisoaporphine, oxoaporphine, and oxoisoaporphine derivatives as anti-AChE and anti-AD agents by the CoMFA method. Journal of Molecular Graphics & Modelling. 41: 61-7. PMID 23500628 DOI: 10.1016/j.jmgm.2013.02.003 |
0.165 |
|
2017 |
Chen L, Chen D, Tang L, Ren J, Chen J, Zhen X, Liu YC, Zhang C, Luo H, Shen J, Xiong B. Design and optimization of purine derivatives as in vivo active PDE10A inhibitors. Bioorganic & Medicinal Chemistry. PMID 28462841 DOI: 10.1016/j.bmc.2017.04.019 |
0.164 |
|
2021 |
Jiang MY, Han C, Zhang C, Zhou Q, Zhang B, Le ML, Huang MX, Wu Y, Luo HB. Discovery of effective phosphodiesterase 2 inhibitors with antioxidant activities for the treatment of alzheimer's disease. Bioorganic & Medicinal Chemistry Letters. 128016. PMID 33838306 DOI: 10.1016/j.bmcl.2021.128016 |
0.164 |
|
2013 |
Zhong J, Huang Y, Ding W, Wu X, Wan J, Luo H. Chemical constituents of Aloe barbadensis Miller and their inhibitory effects on phosphodiesterase-4D. Fitoterapia. 91: 159-65. PMID 24028970 DOI: 10.1016/j.fitote.2013.08.027 |
0.161 |
|
2014 |
Cheng ZB, Deng YL, Fan CQ, Han QH, Lin SL, Tang GH, Luo HB, Yin S. Prostaglandin Derivatives: Nonaromatic Phosphodiesterase-4 Inhibitors from the Soft Coral Sarcophyton ehrenbergi. Journal of Natural Products. PMID 25075977 DOI: 10.1021/np500394d |
0.16 |
|
2018 |
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2022 |
Xue H, Lu J, Yan H, Huang J, Luo HB, Wong MS, Gao Y, Zhang X, Guo L. γ-Glutamyl transpeptidase-activated indole-quinolinium based cyanine as a fluorescence turn-on nucleolus-targeting probe for cancer cell detection and inhibition. Talanta. 237: 122898. PMID 34736714 DOI: 10.1016/j.talanta.2021.122898 |
0.098 |
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2021 |
Sun J, Xiao Z, Haider A, Gebhard C, Xu H, Luo HB, Zhang HT, Josephson L, Wang L, Liang SH. Advances in Cyclic Nucleotide Phosphodiesterase-Targeted PET Imaging and Drug Discovery. Journal of Medicinal Chemistry. 64: 7083-7109. PMID 34042442 DOI: 10.1021/acs.jmedchem.1c00115 |
0.096 |
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2020 |
Feng S, Zhou H, Wu D, Zheng D, Qu B, Liu R, Zhang C, Li Z, Xie Y, Luo HB. Nobiletin and its derivatives overcome multidrug resistance (MDR) in cancer: total synthesis and discovery of potent MDR reversal agents. Acta Pharmaceutica Sinica. B. 10: 327-343. PMID 32082977 DOI: 10.1016/j.apsb.2019.07.007 |
0.096 |
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2008 |
Xie CY, Zhu H, Lin LP, Miao ZH, Geng MY, Cai YJ, Chen Y, Zhao HJ, Luo HB, Zhang XW, Fan LM, Shen YM, Ding J. MFTZ-1, an actinomycetes subspecies derived antitumor macrolide, functions as a novel topoisomerase II poison. Molecular Cancer Therapeutics. 6: 3059-70. PMID 18025289 DOI: 10.1158/1535-7163.Mct-07-0014 |
0.095 |
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2013 |
Luo Z, Sheng J, Sun Y, Lu C, Yan J, Liu A, Luo HB, Huang L, Li X. Synthesis and evaluation of multi-target-directed ligands against Alzheimer's disease based on the fusion of donepezil and ebselen. Journal of Medicinal Chemistry. 56: 9089-99. PMID 24160297 DOI: 10.1021/jm401047q |
0.093 |
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2012 |
Kurouski D, Luo H, Sereda V, Robb FT, Lednev IK. Rapid degradation kinetics of amyloid fibrils under mild conditions by an archaeal chaperonin. Biochemical and Biophysical Research Communications. 422: 97-102. PMID 22564742 DOI: 10.1016/J.Bbrc.2012.04.113 |
0.091 |
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2021 |
Wu Y, Li Z, Zhao YS, Huang YY, Jiang MY, Luo HB. Therapeutic targets and potential agents for the treatment of COVID-19. Medicinal Research Reviews. PMID 33393116 DOI: 10.1002/med.21776 |
0.091 |
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2011 |
Luo H, Zhang P, Robb FT. Oligomerization of an archaeal group II chaperonin is mediated by N-terminal salt bridges. Biochemical and Biophysical Research Communications. 413: 389-94. PMID 21893040 DOI: 10.1016/J.Bbrc.2011.08.112 |
0.088 |
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2017 |
Wang PX, Li ZM, Cai SD, Li JY, He P, Huang Y, Feng GS, Luo HB, Chen SR, Liu PQ. C33(S), a novel PDE9A inhibitor, protects against rat cardiac hypertrophy through upregulating cGMP signaling. Acta Pharmacologica Sinica. PMID 28649129 DOI: 10.1038/aps.2017.38 |
0.085 |
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2019 |
Zhang D, Ye Z, Wei L, Luo HB, Xiao L. Cell Membrane-Coated Porphyrin Metal-Organic Frameworks for Cancer Cell Targeting and O2-Evolving Photodynamic Therapy. Acs Applied Materials & Interfaces. PMID 31577410 DOI: 10.1021/acsami.9b14084 |
0.083 |
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2010 |
LI L, LI G, CHEN L, LUO H, CHEN J, SHEN X, MEI C. Establishment of high throughput screening model for epidermal growth factor receptor tyrosine kinase inhibitor Academic Journal of Second Military Medical University. 29: 1349-1352. DOI: 10.3724/SP.J.1008.2009.01349 |
0.082 |
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2018 |
Sun W, Lee N, Dragulin-Otto S, Wong A, Luo H, Brown A. Effective Filter Screening Approach with Fractionation for Enabling Inline Filtration of Protein A Eluate. Biotechnology and Applied Biochemistry. PMID 30466141 DOI: 10.1002/bab.1713 |
0.081 |
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2018 |
Li X, Wu S, Chen S, Lai Z, Luo HB, Sheng C. One-Pot Synthesis of Deuterated Aldehydes from Arylmethyl Halides. Organic Letters. PMID 29518327 DOI: 10.1021/acs.orglett.8b00016 |
0.08 |
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2019 |
Liang Z, Ou D, Sun D, Tong Y, Luo H, Chen Z. Ultrasensitive biosensor for microRNA-155 using synergistically catalytic nanoprobe coupled with improved cascade strand displacement reaction. Biosensors & Bioelectronics. 146: 111744. PMID 31605986 DOI: 10.1016/j.bios.2019.111744 |
0.078 |
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2022 |
Chen JY, Zhu Q, Cai CZ, Luo HB, Lu JH. α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 101: 154125. PMID 35525236 DOI: 10.1016/j.phymed.2022.154125 |
0.075 |
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2020 |
He Y, Huang Y, Mai C, Pan H, Luo HB, Liu L, Xie Y. The immunomodulatory role of PDEs inhibitors in immune cells: therapeutic implication in rheumatoid arthritis. Pharmacological Research. 105134. PMID 32798648 DOI: 10.1016/j.phrs.2020.105134 |
0.07 |
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2012 |
Wang N, Wang ZY, Mo SL, Loo TY, Wang DM, Luo HB, Yang DP, Chen YL, Shen JG, Chen JP. Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer. Breast Cancer Research and Treatment. 134: 943-55. PMID 22350787 DOI: 10.1007/s10549-012-1977-9 |
0.067 |
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2014 |
Min W, Angileri F, Luo H, Lauria A, Shanmugasundaram M, Almerico AM, Cappello F, de Macario EC, Lednev IK, Macario AJ, Robb FT. A human CCT5 gene mutation causing distal neuropathy impairs hexadecamer assembly in an archaeal model. Scientific Reports. 4: 6688. PMID 25345891 DOI: 10.1038/Srep06688 |
0.066 |
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2020 |
Liu X, Li Z, Liu S, Sun J, Chen Z, Jiang M, Zhang Q, Wei Y, Wang X, Huang YY, Shi Y, Xu Y, Xian H, Bai F, Ou C, ... ... Luo HB, et al. Potential therapeutic effects of dipyridamole in the severely ill patients with COVID-19. Acta Pharmaceutica Sinica. B. PMID 32318327 DOI: 10.1016/J.Apsb.2020.04.008 |
0.063 |
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2021 |
Li Z, Li H, Yu K, Luo HB. Perspective of drug design with high-performance computing. National Science Review. 8: nwab105. PMID 34992787 DOI: 10.1093/nsr/nwab105 |
0.063 |
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2020 |
Wu F, Huang P, Luo H, Wang J, Shen B, Ren Q, He P, Zheng H, Zhang L, Zheng W. Novel lightweight open-cell polypropylene foams for filtering hazardous materials. Rsc Advances. 10: 17694-17701. PMID 35515594 DOI: 10.1039/d0ra01499k |
0.059 |
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2024 |
Huang Y, Yang C, Nie J, Zeng M, Kuang H, Zheng K, Sun H, Xie X, He X, Luo HB, Luo W. The application of drug behavior management methods in the treatment of dental fear and oral diseases in children: A review. Medicine. 103: e37520. PMID 38518036 DOI: 10.1097/MD.0000000000037520 |
0.055 |
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2017 |
Xu W, Jimenez RB, Mowery R, Luo H, Cao M, Agarwal N, Ramos I, Wang X, Wang J. A Quadrupole Dalton-based multi-attribute method for product characterization, process development, and quality control of therapeutic proteins. Mabs. 0. PMID 28805536 DOI: 10.1080/19420862.2017.1364326 |
0.053 |
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2020 |
Liu M, Lu B, Zeng P, Huang B, Xu Y, Liang H, Yang D, Yang S, Luo HB, Lew AM, Masters SL, Geng L, Zeng H, Zhang Y. Compound Heterozygous Mutations of IL12RB1 in a Patient with Selective Defects in Th17 Differentiation. Journal of Clinical Immunology. PMID 32221732 DOI: 10.1007/s10875-020-00771-0 |
0.052 |
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2022 |
Wu KC, Huang CM, Verma KK, Deng ZN, Huang HR, Pang T, Cao HQ, Luo HB, Jiang SL, Xu L. Transcriptomic responses of roots in response to polyethylene glycol - 6000 stimulated drought stress. Frontiers in Plant Science. 13: 992755. PMID 36352884 DOI: 10.3389/fpls.2022.992755 |
0.051 |
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2004 |
Shen X, Xue JH, Yu CY, Luo HB, Qin L, Yu XJ, Chen J, Chen LL, Xiong B, Yue LD, Cai JH, Shen JH, Luo XM, Chen KX, Shi TL, et al. Small envelope protein E of SARS: cloning, expression, purification, CD determination, and bioinformatics analysis. Acta Pharmacologica Sinica. 24: 505-11. PMID 12791175 |
0.051 |
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2023 |
He S, Xie F, Su W, Luo H, Chen D, Cai J, Hong X. Anti-Inflammatory Salidroside Delivery from Chitin Hydrogels for NIR-II Image-Guided Therapy of Atopic Dermatitis. Journal of Functional Biomaterials. 14. PMID 36976074 DOI: 10.3390/jfb14030150 |
0.05 |
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2019 |
Huang P, Wu F, Shen B, Ma X, Zhao Y, Wu M, Wang J, Liu Z, Luo H, Zheng W. Bio-inspired lightweight polypropylene foams with tunable hierarchical tubular porous structure and its application for oil-water separation Chemical Engineering Journal. 370: 1322-1330. DOI: 10.1016/J.CEJ.2019.03.289 |
0.048 |
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2019 |
Luo H, Li Z, Chen J, Pearson C, Wang M, Lv W, Ding H. Integration of Range Split Spectrum Interferometry and conventional InSAR to monitor large gradient surface displacements International Journal of Applied Earth Observation and Geoinformation. 74: 130-137. DOI: 10.1016/J.JAG.2018.09.004 |
0.048 |
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2020 |
Wu F, Huang P, Luo H, Wang J, Shen B, Ren Q, He P, Zheng H, Zhang L, Zheng W. Novel lightweight open-cell polypropylene foams for filtering hazardous materials Rsc Advances. 10: 17694-17701. DOI: 10.1039/d0ra01499k |
0.044 |
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2024 |
Wei Q, Chen L, Luo W, Chen C, Shi Y, Xie J, Xie X, Luo HB. PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis. European Journal of Pharmacology. 967: 176353. PMID 38325798 DOI: 10.1016/j.ejphar.2024.176353 |
0.044 |
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2022 |
Zhang ZW, Gao CS, Zhang H, Yang J, Wang YP, Pan LB, Yu H, He CY, Luo HB, Zhao ZX, Zhou XB, Wang YL, Fu J, Han P, Dong YH, et al. oligosaccharides increase serotonin in the brain and ameliorate depression promoting 5-hydroxytryptophan production in the gut microbiota. Acta Pharmaceutica Sinica. B. 12: 3298-3312. PMID 35967282 DOI: 10.1016/j.apsb.2022.02.032 |
0.042 |
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2018 |
Huang XF, Jiang WT, Liu L, Song FC, Zhu X, Shi GL, Ding SM, Ke HM, Wang W, O'Donnell JM, Zhang HT, Luo HB, Wan YQ, Song GQ, Xu Y. A novel PDE9 inhibitor WYQ-C36D ameliorates corticosterone-induced neurotoxicity and depression-like behaviors by cGMP-CREB-related signaling. Cns Neuroscience & Therapeutics. PMID 29722134 DOI: 10.1111/Cns.12864 |
0.039 |
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2020 |
Guo L, Liu X, Zhang T, Luo H, Fan HH, Wong MS. Star-shaped triazine-cored ladder-type ter(p-phenylene)s for high-performance multiphoton absorption and amplified spontaneous blue emission Journal of Materials Chemistry C. 8: 1768-1772. DOI: 10.1039/c9tc06025a |
0.039 |
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2021 |
Guo L, Wei R, Sun R, Yang Q, Li G, Wang L, Luo H, Feng M. "Cytokine-microfactories" recruit DCs and deliver tumor antigens via gap junctions for immunotherapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 34324896 DOI: 10.1016/j.jconrel.2021.07.040 |
0.038 |
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2020 |
Lu B, Liu M, Wang J, Fan H, Yang D, Zhang L, Gu X, Nie J, Chen Z, Corbett AJ, Zhan MJ, Zhang S, Bryant VL, Lew AM, McCluskey J, ... Luo HB, et al. IL-17 production by tissue-resident MAIT cells is locally induced in children with pneumonia. Mucosal Immunology. PMID 32112047 DOI: 10.1038/S41385-020-0273-Y |
0.034 |
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2011 |
Zhu SY, Li YH, Ma HM, Huang TT, Luo HB, Dou J, Du ML. Stanozolol regulates proliferation of growth plate chondrocytes via activation of ERalpha in GnRHa-treated adolescent rats. Journal of Pediatric Endocrinology & Metabolism : Jpem. 24: 275-81. PMID 21823523 |
0.029 |
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2019 |
Huang P, Wu F, Pang Y, Wu M, Lan X, Luo H, Shen B, Zheng W. Enhanced dispersion, flame retardancy and mechanical properties of polypropylene/intumescent flame retardant composites via supercritical CO2 foaming followed by defoaming Composites Science and Technology. 171: 282-290. DOI: 10.1016/J.COMPSCITECH.2018.12.029 |
0.026 |
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2020 |
Feng SL, Luo HB, Cai L, Zhang J, Wang D, Chen YJ, Zhan HX, Jiang ZH, Xie Y. Ginsenoside Rg5 overcomes chemotherapeutic multidrug resistance mediated by ABCB1 transporter: and study. Journal of Ginseng Research. 44: 247-257. PMID 32148406 DOI: 10.1016/j.jgr.2018.10.007 |
0.025 |
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2021 |
Liu M, Lu B, Fan H, Guo X, Du S, Yang D, Xu Y, Li Y, Che D, Liu Y, Gu X, Ding T, Wang P, Luo HB, Lu G. Heightened Local T17 Cell Inflammation Is Associated with Severe Community-Acquired Pneumonia in Children under the Age of 1 Year. Mediators of Inflammation. 2021: 9955168. PMID 34602860 DOI: 10.1155/2021/9955168 |
0.022 |
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2021 |
Zhang K, Jiang F, Luo H, Liu F. Occupational noise exposure and the prevalence of dyslipidemia in a cross-sectional study. Bmc Public Health. 21: 1258. PMID 34187444 DOI: 10.1186/s12889-021-11274-x |
0.017 |
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2020 |
Wu F, Li Y, Lan X, Huang P, Chong Y, Luo H, Shen B, Zheng W. Large-scale fabrication of lightweight, tough polypropylene/carbon black composite foams as broadband microwave absorbers Composites Communications. 20: 100358. DOI: 10.1016/j.coco.2020.100358 |
0.016 |
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2019 |
Huang P, Wu M, Pang Y, Shen B, Wu F, Lan X, Luo H, Zheng W. Ultrastrong, flexible and lightweight anisotropic polypropylene foams with superior flame retardancy Composites Part a: Applied Science and Manufacturing. 116: 180-186. DOI: 10.1016/J.COMPOSITESA.2018.10.027 |
0.01 |
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