James J. Chambers, Ph.D. - Publications

2004-2007 MCB University of California, Berkeley, Berkeley, CA 
 2008- Chemistry University of Massachusetts, Amherst, Amherst, MA 
Chemical Biology, Neuroscience

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 McCarron ST, Chambers JJ. Modular chemical probes for visualizing and tracking endogenous ion channels. Neuropharmacology. PMID 25866020 DOI: 10.1016/j.neuropharm.2015.03.033  1
2015 Combs-Bachmann RE, Johnson JN, Vytla D, Hussey AM, Kilfoil ML, Chambers JJ. Ligand-directed delivery of fluorophores to track native calcium-permeable AMPA receptors in neuronal cultures. Journal of Neurochemistry. 133: 320-9. PMID 25640258 DOI: 10.1111/jnc.13051  1
2015 Hussey AM, Chambers JJ. Methods to locate and track ion channels and receptors expressed in live neurons. Acs Chemical Neuroscience. 6: 189-98. PMID 25307447 DOI: 10.1021/cn5002057  1
2014 Lin WC, Davenport CM, Mourot A, Vytla D, Smith CM, Medeiros KA, Chambers JJ, Kramer RH. Engineering a light-regulated GABAA receptor for optical control of neural inhibition. Acs Chemical Biology. 9: 1414-9. PMID 24819442 DOI: 10.1021/cb500167u  1
2014 Gann AW, Amoroso JW, Einck VJ, Rice WP, Chambers JJ, Schnarr NA. A photoinduced, benzyne click reaction. Organic Letters. 16: 2003-5. PMID 24625300 DOI: 10.1021/ol500389t  1
2014 Stoffolano JG, Croke K, Chambers J, Gäde G, Solari P, Liscia A. Role of Phote-HrTH (Phormia terraenovae hypertrehalosemic hormone) in modulating the supercontractile muscles of the crop of adult Phormia regina Meigen Journal of Insect Physiology. 71: 147-155. DOI: 10.1016/j.jinsphys.2014.10.014  1
2013 Stoffolano JG, Danai L, Chambers J. Effect of channel blockers on the smooth muscle of the adult crop of the queen blowfly, Phormia regina Journal of Insect Science. 13. PMID 24205919 DOI: 10.1673/031.013.9701  1
2013 McCarron ST, Feliciano M, Johnson JN, Chambers JJ. Photoinitiated release of an aziridinium ion precursor for the temporally controlled alkylation of nucleophiles. Bioorganic & Medicinal Chemistry Letters. 23: 2395-8. PMID 23489632 DOI: 10.1016/j.bmcl.2013.02.044  1
2012 Chambers JJ. Delivery of therapeutics to the central nervous system. Advanced Drug Delivery Reviews. 64: 589. PMID 22388004 DOI: 10.1016/j.addr.2012.02.009  1
2012 Vytla D, Combs-Bachmann RE, Hussey AM, McCarron ST, McCarthy DS, Chambers JJ. Prodrug approaches to reduce hyperexcitation in the CNS. Advanced Drug Delivery Reviews. 64: 666-85. PMID 22138074 DOI: 10.1016/j.addr.2011.11.007  1
2011 Vytla D, Combs-Bachmann RE, Hussey AM, Hafez I, Chambers JJ. Silent, fluorescent labeling of native neuronal receptors. Organic & Biomolecular Chemistry. 9: 7151-61. PMID 21897969 DOI: 10.1039/c1ob05963g  1
2011 Jackman SL, Babai N, Chambers JJ, Thoreson WB, Kramer RH. A positive feedback synapse from retinal horizontal cells to cone photoreceptors. Plos Biology. 9: e1001057. PMID 21559323 DOI: 10.1371/journal.pbio.1001057  1
2011 Chambers JJ, Kramer RH. Introduction to part III: Small molecule photoswitches Neuromethods. 55: 167-169. DOI: 10.1007/978-1-61779-031-7_9  1
2011 Chambers JJ, Kramer RH. Introduction to part II: Natural photosensitive proteins Neuromethods. 55: 95-97. DOI: 10.1007/978-1-61779-031-7_5  1
2011 Chambers JJ, Kramer RH. Introduction to part I: Caged neurotransmitters Neuromethods. 55: 3-5. DOI: 10.1007/978-1-61779-031-7_1  1
2011 Chambers JJ, Kramer RH. Neuromethods: Preface Neuromethods. 55: vii-ix.  1
2010 Feliciano M, Vytla D, Medeiros KA, Chambers JJ. The GABA(A) receptor as a target for photochromic molecules. Bioorganic & Medicinal Chemistry. 18: 7731-8. PMID 20646926 DOI: 10.1016/j.bmc.2010.05.056  1
2008 Chambers JJ, Kramer RH. Light-activated ion channels for remote control of neural activity. Methods in Cell Biology. 90: 217-32. PMID 19195553 DOI: 10.1016/S0091-679X(08)00811-X  1
2007 McGarry K, Chambers J, Oatley G. A multi-layered approach to protein data integration for diabetes research Artificial Intelligence in Medicine. 41: 129-143. PMID 17869073 DOI: 10.1016/j.artmed.2007.07.009  1
2006 Chambers JJ, Banghart MR, Trauner D, Kramer RH. Light-induced depolarization of neurons using a modified Shaker K(+) channel and a molecular photoswitch. Journal of Neurophysiology. 96: 2792-6. PMID 16870840 DOI: 10.1152/jn.00318.2006  1
2006 McLean TH, Chambers JJ, Parrish JC, Braden MR, Marona-Lewicka D, Kurrasch-Orbaugh D, Nichols DE. C-(4,5,6-trimethoxyindan-1-yl)methanamine: a mescaline analogue designed using a homology model of the 5-HT2A receptor. Journal of Medicinal Chemistry. 49: 4269-74. PMID 16821786 DOI: 10.1021/jm060272y  1
2005 Kramer RH, Chambers JJ, Trauner D. Photochemical tools for remote control of ion channels in excitable cells. Nature Chemical Biology. 1: 360-5. PMID 16370371  1
2004 Chambers JJ, Gouda H, Young DM, Kuntz ID, England PM. Photochemically knocking out glutamate receptors in vivo. Journal of the American Chemical Society. 126: 13886-7. PMID 15506725 DOI: 10.1021/ja048331p  1
2003 Chambers JJ, Parrish JC, Jensen NH, Kurrasch-Orbaugh DM, Marona-Lewicka D, Nichols DE. Synthesis and pharmacological characterization of a series of geometrically constrained 5-HT(2A/2C) receptor ligands. Journal of Medicinal Chemistry. 46: 3526-35. PMID 12877591 DOI: 10.1021/jm030064v  1
2002 Chambers JJ, Nichols DE. A homology-based model of the human 5-HT2A receptor derived from an in silico activated G-protein coupled receptor. Journal of Computer-Aided Molecular Design. 16: 511-20. PMID 12510883 DOI: 10.1023/A:1021275430021  1
2002 Chambers JJ, Kurrasch-Orbaugh DM, Nichols DE. Translocation of the 5-alkoxy substituent of 2,5-dialkoxyarylalkylamines to the 6-position: effects on 5-HT(2A/2C) receptor affinity. Bioorganic & Medicinal Chemistry Letters. 12: 1997-9. PMID 12113827 DOI: 10.1016/S0960-894X(02)00306-2  1
2001 Chambers JJ, Kurrasch-Orbaugh DM, Parker MA, Nichols DE. Enantiospecific synthesis and pharmacological evaluation of a series of super-potent, conformationally restricted 5-HT(2A/2C) receptor agonists. Journal of Medicinal Chemistry. 44: 1003-10. PMID 11300881 DOI: 10.1021/jm000491y  1
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