Wallace L. McKeehan, PhD - Publications

Affiliations: 
Biochemistry and Biophysics Texas A & M University, College Station, TX, United States 
Area:
Fibroblast Growth Factor Signaling, Cancer Biology, Nutrition
Website:
http://www.ibt.tamhsc.edu/faculty/bio-wmckeehan.html

202 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Liu J, Chen G, Liu Z, Liu S, Cai Z, You P, Ke Y, Lai L, Huang Y, Gao H, Zhao L, Pelicano H, Huang P, McKeehan WL, Wu CL, et al. Aberrant FGFR tyrosine kinase signaling enhances the Warburg effect by reprogramming LDH isoform expression and activity in prostate cancer. Cancer Research. PMID 29891507 DOI: 10.1158/0008-5472.CAN-17-3226  1
2016 Li X, Wang C, Xiao J, McKeehan WL, Wang F. Fibroblast growth factors, old kids on the new block. Seminars in Cell & Developmental Biology. PMID 26768548 DOI: 10.1016/j.semcdb.2015.12.014  1
2016 Li W, Zou J, Yue F, Song K, Chen Q, McKeehan WL, Wang F, Xu G, Huang H, Yi J, Liu L. Defects in MAP1S-mediated autophagy cause reduction in mouse lifespans especially when fibronectin is overexpressed. Aging Cell. PMID 26750654 DOI: 10.1111/acel.12441  1
2015 Shi M, Zhang Y, Liu L, Zhang T, Han F, Cleveland J, Wang F, McKeehan WL, Li Y, Zhang D. MAP1S regulates the phagocytosis of bacteria and TLR signaling. The Journal of Biological Chemistry. PMID 26565030 DOI: 10.1074/jbc.M115.687376  1
2015 Yue F, Li W, Zou J, Chen Q, Xu G, Huang H, Xu Z, Zhang S, Gallinari P, Wang F, McKeehan WL, Liu L. Blocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin. Aging. 7: 839-853. PMID 26540094  1
2015 Huang Y, Jin C, Hamana T, Liu J, Wang C, An L, McKeehan WL, Wang F. Overexpression of FGF9 in Prostate Epithelial Cells Augments Reactive Stroma Formation and Promotes Prostate Cancer Progression. International Journal of Biological Sciences. 11: 948-60. PMID 26157349 DOI: 10.7150/ijbs.12468  1
2015 Liu J, You P, Chen G, Fu X, Zeng X, Wang C, Huang Y, An L, Wan X, Navone N, Wu CL, McKeehan WL, Zhang Z, Zhong W, Wang F. Hyperactivated FRS2α-mediated signaling in prostate cancer cells promotes tumor angiogenesis and predicts poor clinical outcome of patients. Oncogene. PMID 26096936 DOI: 10.1038/onc.2015.239  1
2015 Huang Y, Hamana T, Liu J, Wang C, An L, You P, Chang JY, Xu J, McKeehan WL, Wang F. Prostate Sphere-forming Stem Cells Are Derived from the P63-expressing Basal Compartment. The Journal of Biological Chemistry. 290: 17745-52. PMID 26032419 DOI: 10.1074/jbc.M115.661033  1
2015 Huang Y, Hamana T, Liu J, Wang C, An L, You P, Chang JY, Xu J, Jin C, Zhang Z, McKeehan WL, Wang F. Type 2 Fibroblast Growth Factor Receptor Signaling Preserves Stemness and Prevents Differentiation of Prostate Stem Cells from the Basal Compartment. The Journal of Biological Chemistry. 290: 17753-61. PMID 26032417 DOI: 10.1074/jbc.M115.661066  1
2015 Wang F, Luo Y, McKeehan WL. The FGF signaling axis in prostate tumorigenesis Molecular Oncology: Causes of Cancer and Targets For Treatment. 190-203. DOI: 10.1017/CBO9781139046947.017  1
2014 Wang C, Yang C, Chang JY, You P, Li Y, Jin C, Luo Y, Li X, McKeehan WL, Wang F. Hepatocyte FRS2α is essential for the endocrine fibroblast growth factor to limit the amplitude of bile acid production induced by prandial activity. Current Molecular Medicine. 14: 703-11. PMID 25056539 DOI: 10.2174/1566524014666140724095112  1
2014 Fuentes-Mattei E, Velazquez-Torres G, Phan L, Zhang F, Chou PC, Shin JH, Choi HH, Chen JS, Zhao R, Chen J, Gully C, Carlock C, Qi Y, Zhang Y, Wu Y, ... ... McKeehan WL, et al. Effects of obesity on transcriptomic changes and cancer hallmarks in estrogen receptor-positive breast cancer. Journal of the National Cancer Institute. 106. PMID 24957076 DOI: 10.1093/jnci/dju158  1
2014 Shoji K, Teishima J, Hayashi T, Ohara S, Mckeehan WL, Matsubara A. Restoration of fibroblast growth factor receptor 2IIIb enhances the chemosensitivity of human prostate cancer cells. Oncology Reports. 32: 65-70. PMID 24839986 DOI: 10.3892/or.2014.3200  1
2014 Jung D, York JP, Wang L, Yang C, Zhang A, Francis HL, Webb P, McKeehan WL, Alpini G, Lesage GD, Moore DD, Xia X. FXR-induced secretion of FGF15/19 inhibits CYP27 expression in cholangiocytes through p38 kinase pathway. PflüGers Archiv : European Journal of Physiology. 466: 1011-9. PMID 24068255 DOI: 10.1007/s00424-013-1364-3  1
2013 Luo Y, McKeehan WL. Stressed Liver and Muscle Call on Adipocytes with FGF21. Frontiers in Endocrinology. 4: 194. PMID 24385972 DOI: 10.3389/fendo.2013.00194  1
2013 Luo Y, Yang C, Ye M, Jin C, Abbruzzese JL, Lee MH, Yeung SC, McKeehan WL. Deficiency of metabolic regulator FGFR4 delays breast cancer progression through systemic and microenvironmental metabolic alterations. Cancer & Metabolism. 1: 21. PMID 24279986 DOI: 10.1186/2049-3002-1-21  0.68
2013 Corn PG, Wang F, McKeehan WL, Navone N. Targeting fibroblast growth factor pathways in prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 5856-66. PMID 24052019 DOI: 10.1158/1078-0432.CCR-13-1550  1
2013 Chang JY, Wang C, Liu J, Huang Y, Jin C, Yang C, Hai B, Liu F, D'Souza RN, McKeehan WL, Wang F. Fibroblast growth factor signaling is essential for self-renewal of dental epithelial stem cells. The Journal of Biological Chemistry. 288: 28952-61. PMID 23979135 DOI: 10.1074/jbc.M113.506873  1
2013 Chang JY, Wang C, Jin C, Yang C, Huang Y, Liu J, McKeehan WL, D'Souza RN, Wang F. Self-renewal and multilineage differentiation of mouse dental epithelial stem cells. Stem Cell Research. 11: 990-1002. PMID 23906788 DOI: 10.1016/j.scr.2013.06.008  1
2013 Wang C, Chang JY, Yang C, Huang Y, Liu J, You P, McKeehan WL, Wang F, Li X. Type 1 fibroblast growth factor receptor in cranial neural crest cell-derived mesenchyme is required for palatogenesis. The Journal of Biological Chemistry. 288: 22174-83. PMID 23754280 DOI: 10.1074/jbc.M113.463620  1
2013 Yang C, Lu W, Lin T, You P, Ye M, Huang Y, Jiang X, Wang C, Wang F, Lee MH, Yeung SC, Johnson RL, Wei C, Tsai RY, Frazier ML, ... McKeehan WL, et al. Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress. Bmc Gastroenterology. 13: 67. PMID 23590285 DOI: 10.1186/1471-230X-13-67  1
2013 Emmenegger BA, Hwang EI, Moore C, Markant SL, Brun SN, Dutton JW, Read TA, Fogarty MP, Singh AR, Durden DL, Yang C, McKeehan WL, Wechsler-Reya RJ. Distinct roles for fibroblast growth factor signaling in cerebellar development and medulloblastoma. Oncogene. 32: 4181-8. PMID 23045271 DOI: 10.1038/onc.2012.440  1
2012 Yang C, Wang C, Ye M, Jin C, He W, Wang F, McKeehan WL, Luo Y. Control of lipid metabolism by adipocyte FGFR1-mediated adipohepatic communication during hepatic stress. Nutrition & Metabolism. 9: 94. PMID 23106963 DOI: 10.1186/1743-7075-9-94  1
2012 Dong W, Lu W, McKeehan WL, Luo Y, Ye S. Structural basis of heparan sulfate-specific degradation by heparinase III. Protein & Cell. 3: 950-61. PMID 23011846 DOI: 10.1007/s13238-012-2056-z  1
2012 McKeehan WL. A tribute to Richard G. Ham (1932-2011). In Vitro Cellular & Developmental Biology. Animal. 48: 259-70. PMID 22580908 DOI: 10.1007/s11626-012-9509-9  1
2012 Yang C, Jin C, Li X, Wang F, McKeehan WL, Luo Y. Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB. Plos One. 7: e33870. PMID 22442730 DOI: 10.1371/journal.pone.0033870  1
2012 Zhang J, Liu J, Liu L, McKeehan WL, Wang F. The fibroblast growth factor signaling axis controls cardiac stem cell differentiation through regulating autophagy. Autophagy. 8: 690-1. PMID 22302007 DOI: 10.4161/auto.19290  1
2012 Liu L, McKeehan WL, Wang F, Xie R. MAP1S enhances autophagy to suppress tumorigenesis. Autophagy. 8: 278-80. PMID 22301994 DOI: 10.4161/auto.8.2.18939  1
2012 Yang X, Li Q, Lin X, Ma Y, Yue X, Tao Z, Wang F, Mckeehan WL, Wei L, Schwartz RJ, Chang J. Mechanism of fibrotic cardiomyopathy in mice expressing truncated Rho-associated coiled-coil protein kinase 1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2105-16. PMID 22278938 DOI: 10.1096/fj.11-201319  1
2012 Zhang J, Liu J, Huang Y, Chang JY, Liu L, McKeehan WL, Martin JF, Wang F. FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity. Circulation Research. 110: e29-39. PMID 22207710 DOI: 10.1161/CIRCRESAHA.111.255950  1
2011 Xie R, Wang F, McKeehan WL, Liu L. Autophagy enhanced by microtubule- and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogenesis. Cancer Research. 71: 7537-46. PMID 22037873 DOI: 10.1158/0008-5472.CAN-11-2170  1
2011 Lin X, Zhang Y, Liu L, McKeehan WL, Shen Y, Song S, Wang F. FRS2α is essential for the fibroblast growth factor to regulate the mTOR pathway and autophagy in mouse embryonic fibroblasts. International Journal of Biological Sciences. 7: 1114-21. PMID 21927580  1
2011 Jin C, Yang C, Wu X, Wang F, McKeehan WL. FGFR3-expressing smooth muscle-like stromal cells differentiate in response to FGFR2IIIb-expressing prostate tumor cells and delay tumor progression. In Vitro Cellular & Developmental Biology. Animal. 47: 500-5. PMID 21691921 DOI: 10.1007/s11626-011-9432-5  1
2011 Kobayashi M, Huang Y, Jin C, Luo Y, Okamoto T, Wang F, McKeehan WL. FGFR1 abrogates inhibitory effect of androgen receptor concurrent with induction of androgen-receptor variants in androgen receptor-negative prostate tumor epithelial cells. The Prostate. 71: 1691-700. PMID 21446013 DOI: 10.1002/pros.21386  1
2011 Xie R, Nguyen S, McKeehan K, Wang F, McKeehan WL, Liu L. Microtubule-associated protein 1S (MAP1S) bridges autophagic components with microtubules and mitochondria to affect autophagosomal biogenesis and degradation. The Journal of Biological Chemistry. 286: 10367-77. PMID 21262964 DOI: 10.1074/jbc.M110.206532  1
2010 Xie R, Nguyen S, McKeehan WL, Liu L. Acetylated microtubules are required for fusion of autophagosomes with lysosomes. Bmc Cell Biology. 11: 89. PMID 21092184 DOI: 10.1186/1471-2121-11-89  1
2010 Luo Y, Yang C, Lu W, Xie R, Jin C, Huang P, Wang F, McKeehan WL. Metabolic regulator betaKlotho interacts with fibroblast growth factor receptor 4 (FGFR4) to induce apoptosis and inhibit tumor cell proliferation. The Journal of Biological Chemistry. 285: 30069-78. PMID 20657013 DOI: 10.1074/jbc.M110.148288  1
2010 Sato GH, Sato JD, Okamoto T, McKeehan WL, Barnes DW. Tissue culture: the unlimited potential. In Vitro Cellular & Developmental Biology. Animal. 46: 590-4. PMID 20512426 DOI: 10.1007/s11626-010-9315-1  1
2010 McKeehan WL, Wang F, Luo Y. The fibroblast growth factor (fgf) signaling complex Handbook of Cell Signaling, 2/E. 1: 253-259. DOI: 10.1016/B978-0-12-374145-5.00038-3  1
2009 Liu L, Xie R, Yang C, McKeehan WL. Dual function microtubule- and mitochondria-associated proteins mediate mitotic cell death. Cellular Oncology : the Official Journal of the International Society For Cellular Oncology. 31: 393-405. PMID 19759419 DOI: 10.3233/CLO-2009-0484  1
2009 Liu L, Xie R, Nguyen S, Ye M, McKeehan WL. Robust autophagy/mitophagy persists during mitosis. Cell Cycle (Georgetown, Tex.). 8: 1616-20. PMID 19411827  1
2009 Luo Y, Yang C, Jin C, Xie R, Wang F, McKeehan WL. Novel phosphotyrosine targets of FGFR2IIIb signaling. Cellular Signalling. 21: 1370-8. PMID 19410646 DOI: 10.1016/j.cellsig.2009.04.004  1
2009 Huang X, Yang C, Jin C, Luo Y, Wang F, McKeehan WL. Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis. Molecular Carcinogenesis. 48: 553-62. PMID 19009564 DOI: 10.1002/mc.20494  1
2008 Matsubara A, Teishima J, Mirkhat S, Yasumoto H, Mochizuki H, Seki M, Mutaguchi K, Mckeehan WL, Usui T. Restoration of FGF receptor type 2 enhances radiosensitivity of hormone-refractory human prostate carcinoma PC-3 cells. Anticancer Research. 28: 2141-6. PMID 18751387  1
2008 Zhang Y, Zhang J, Lin Y, Lan Y, Lin C, Xuan JW, Shen MM, McKeehan WL, Greenberg NM, Wang F. Role of epithelial cell fibroblast growth factor receptor substrate 2alpha in prostate development, regeneration and tumorigenesis. Development (Cambridge, England). 135: 775-84. PMID 18184727 DOI: 10.1242/dev.009910  1
2007 Huang X, Yang C, Luo Y, Jin C, Wang F, McKeehan WL. FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver. Diabetes. 56: 2501-10. PMID 17664243 DOI: 10.2337/db07-0648  1
2007 Eriksson M, Samuelsson H, Samuelsson EB, Liu L, McKeehan WL, Benedikz E, Sundström E. The NMDAR subunit NR3A interacts with microtubule-associated protein 1S in the brain. Biochemical and Biophysical Research Communications. 361: 127-32. PMID 17658481 DOI: 10.1016/j.bbrc.2007.06.179  1
2007 Gunasekera RS, Sewgobind K, Desai S, Dunn L, Black HS, McKeehan WL, Patil B. Lycopene and lutein inhibit proliferation in rat prostate carcinoma cells. Nutrition and Cancer. 58: 171-7. PMID 17640163 DOI: 10.1080/01635580701328339  1
2007 Moss TN, Vo A, McKeehan WL, Liu L. UXT (Ubiquitously Expressed Transcript) causes mitochondrial aggregation. In Vitro Cellular & Developmental Biology. Animal. 43: 139-46. PMID 17554592 DOI: 10.1007/s11626-007-9016-6  1
2007 Luo Y, Huang X, McKeehan WL. High yield, purity and activity of soluble recombinant Bacteroides thetaiotaomicron GST-heparinase I from Escherichia coli. Archives of Biochemistry and Biophysics. 460: 17-24. PMID 17346663 DOI: 10.1016/j.abb.2007.01.029  1
2007 Lin Y, Liu G, Zhang Y, Hu YP, Yu K, Lin C, McKeehan K, Xuan JW, Ornitz DM, Shen MM, Greenberg N, McKeehan WL, Wang F. Fibroblast growth factor receptor 2 tyrosine kinase is required for prostatic morphogenesis and the acquisition of strict androgen dependency for adult tissue homeostasis. Development (Cambridge, England). 134: 723-34. PMID 17215304 DOI: 10.1242/dev.02765  1
2006 Huang X, Yu C, Jin C, Yang C, Xie R, Cao D, Wang F, McKeehan WL. Forced expression of hepatocyte-specific fibroblast growth factor 21 delays initiation of chemically induced hepatocarcinogenesis. Molecular Carcinogenesis. 45: 934-42. PMID 16929488 DOI: 10.1002/mc.20241  1
2006 Luo Y, Ye S, Kan M, McKeehan WL. Control of fibroblast growth factor (FGF) 7- and FGF1-induced mitogenesis and downstream signaling by distinct heparin octasaccharide motifs. The Journal of Biological Chemistry. 281: 21052-61. PMID 16728399 DOI: 10.1074/jbc.M601559200  1
2006 Newman EA, Muh SJ, Hovhannisyan RH, Warzecha CC, Jones RB, McKeehan WL, Carstens RP. Identification of RNA-binding proteins that regulate FGFR2 splicing through the use of sensitive and specific dual color fluorescence minigene assays. Rna (New York, N.Y.). 12: 1129-41. PMID 16603716 DOI: 10.1261/rna.34906  1
2006 Huang X, Yu C, Jin C, Kobayashi M, Bowles CA, Wang F, McKeehan WL. Ectopic activity of fibroblast growth factor receptor 1 in hepatocytes accelerates hepatocarcinogenesis by driving proliferation and vascular endothelial growth factor-induced angiogenesis. Cancer Research. 66: 1481-90. PMID 16452204 DOI: 10.1158/0008-5472.CAN-05-2412  1
2006 Luo Y, Ye S, Kan M, McKeehan WL. Structural specificity in a FGF7-affinity purified heparin octasaccharide required for formation of a complex with FGF7 and FGFR2IIIb. Journal of Cellular Biochemistry. 97: 1241-58. PMID 16315317 DOI: 10.1002/jcb.20724  1
2006 Gutierrez A, Ratliff EP, Andres AM, Huang X, McKeehan WL, Davis RA. Bile acids decrease hepatic paraoxonase 1 expression and plasma high-density lipoprotein levels via FXR-mediated signaling of FGFR4. Arteriosclerosis, Thrombosis, and Vascular Biology. 26: 301-6. PMID 16284190 DOI: 10.1161/01.ATV.0000195793.73118.b4  1
2006 Zhao P, Caretti G, Mitchell S, McKeehan WL, Boskey AL, Pachman LM, Sartorelli V, Hoffman EP. Fgfr4 is required for effective muscle regeneration in vivo. Delineation of a MyoD-Tead2-Fgfr4 transcriptional pathway. The Journal of Biological Chemistry. 281: 429-38. PMID 16267055 DOI: 10.1074/jbc.M507440200  1
2005 Liu L, Vo A, Liu G, McKeehan WL. Putative tumor suppressor RASSF1 interactive protein and cell death inducer C19ORF5 is a DNA binding protein. Biochemical and Biophysical Research Communications. 332: 670-6. PMID 15907802 DOI: 10.1016/j.bbrc.2005.05.006  1
2005 Liu L, Vo A, Liu G, McKeehan WL. Distinct structural domains within C19ORF5 support association with stabilized microtubules and mitochondrial aggregation and genome destruction. Cancer Research. 65: 4191-201. PMID 15899810 DOI: 10.1158/0008-5472.CAN-04-3865  1
2005 Liu L, Vo A, McKeehan WL. Specificity of the methylation-suppressed A isoform of candidate tumor suppressor RASSF1 for microtubule hyperstabilization is determined by cell death inducer C19ORF5. Cancer Research. 65: 1830-8. PMID 15753381 DOI: 10.1158/0008-5472.CAN-04-3896  1
2005 Yu C, Wang F, Jin C, Huang X, McKeehan WL. Independent repression of bile acid synthesis and activation of c-Jun N-terminal kinase (JNK) by activated hepatocyte fibroblast growth factor receptor 4 (FGFR4) and bile acids. The Journal of Biological Chemistry. 280: 17707-14. PMID 15750181 DOI: 10.1074/jbc.M411771200  1
2005 McKeehan WL. Letter from the Editor: Dr. J. Denry Sato takes over as editor-in-chief In Vitro Cellular and Developmental Biology - Animal. 41: 125. DOI: 10.1290/050100601.1  1
2004 Yasumoto H, Matsubara A, Mutaguchi K, Usui T, McKeehan WL. Restoration of fibroblast growth factor receptor2 suppresses growth and tumorigenicity of malignant human prostate carcinoma PC-3 cells. The Prostate. 61: 236-42. PMID 15368475 DOI: 10.1002/pros.20093  1
2004 Jin C, Wang F, Wu X, Yu C, Luo Y, McKeehan WL. Directionally specific paracrine communication mediated by epithelial FGF9 to stromal FGFR3 in two-compartment premalignant prostate tumors. Cancer Research. 64: 4555-62. PMID 15231666 DOI: 10.1158/0008-5472.CAN-03-3752  1
2004 Luo Y, Cho HH, Jones RB, Jin C, McKeehan WL. Improved production of recombinant fibroblast growth factor 7 (FGF7/KGF) from bacteria in high magnesium chloride. Protein Expression and Purification. 33: 326-31. PMID 14711521 DOI: 10.1016/j.pep.2003.10.013  1
2004 Wang F, McKeehan K, Yu C, Ittmann M, McKeehan WL. Chronic activity of ectopic type 1 fibroblast growth factor receptor tyrosine kinase in prostate epithelium results in hyperplasia accompanied by intraepithelial neoplasia. The Prostate. 58: 1-12. PMID 14673947 DOI: 10.1002/pros.10311  1
2003 Jin C, McKeehan K, Guo W, Jauma S, Ittmann MM, Foster B, Greenberg NM, McKeehan WL, Wang F. Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate. Cancer Research. 63: 8784-90. PMID 14695195  1
2003 Yu C, Wang F, Jin C, Huang X, Miller DL, Basilico C, McKeehan WL. Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis. The American Journal of Pathology. 163: 1653-62. PMID 14507672 DOI: 10.1016/S0002-9440(10)63522-5  1
2003 Luo Y, Cho HH, McKeehan WL. Biospecific extraction and neutralization of anticoagulant heparin with fibroblast growth factors (FGF). Journal of Pharmaceutical Sciences. 92: 2117-27. PMID 14502551 DOI: 10.1002/jps.10472  1
2003 Wu X, Jin C, Wang F, Yu C, McKeehan WL. Stromal cell heterogeneity in fibroblast growth factor-mediated stromal-epithelial cell cross-talk in premalignant prostate tumors. Cancer Research. 63: 4936-44. PMID 12941818  1
2002 Liu L, Amy V, Liu G, McKeehan WL. Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells. In Vitro Cellular & Developmental Biology. Animal. 38: 582-94. PMID 12762840 DOI: 10.1290/1543-706X(2002)38<582:NCIMAT>2.0.CO;2  1
2002 Yu C, Wang F, Jin C, Wu X, Chan WK, McKeehan WL. Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice. The American Journal of Pathology. 161: 2003-10. PMID 12466116 DOI: 10.1016/S0002-9440(10)64478-1  1
2002 Burger PE, Coetzee S, McKeehan WL, Kan M, Cook P, Fan Y, Suda T, Hebbel RP, Novitzky N, Muller WA, Wilson EL. Fibroblast growth factor receptor-1 is expressed by endothelial progenitor cells. Blood. 100: 3527-35. PMID 12411316 DOI: 10.1182/blood.V100.10.3527  1
2002 Wang F, McKeehan K, Yu C, McKeehan WL. Fibroblast growth factor receptor 1 phosphotyrosine 766: molecular target for prevention of progression of prostate tumors to malignancy. Cancer Research. 62: 1898-903. PMID 11912171  1
2002 Liu L, McKeehan WL. Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity. Genomics. 79: 124-36. PMID 11827465 DOI: 10.1006/geno.2001.6679  1
2002 Sato G, McKeehan WL. Lifetime achievement award lecture: More questions than answers In Vitro Cellular and Developmental Biology - Animal. 38: 429-435. DOI: 10.1290/1071-2690(2002)038<0429:LAALMQ>2.0.CO;2  1
2002 Liu Y, Ahmad H, Luo Y, Gardiner DT, Gunasekera RS, McKeehan WL, Patil BS. Influence of harvest time on citrus pectin and its in vitro inhibition of fibroblast growth factor signal transduction Journal of the Science of Food and Agriculture. 82: 469-477. DOI: 10.1002/jsfa.1037  1
2001 Ye S, Luo Y, Lu W, Jones RB, Linhardt RJ, Capila I, Toida T, Kan M, Pelletier H, McKeehan WL. Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs. Biochemistry. 40: 14429-39. PMID 11724555 DOI: 10.1021/bi011000u  1
2001 Zhang Y, Wang H, Toratani S, Sato JD, Kan M, McKeehan WL, Okamoto T. Growth inhibition by keratinocyte growth factor receptor of human salivary adenocarcinoma cells through induction of differentiation and apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 98: 11336-40. PMID 11562460 DOI: 10.1073/pnas.191377098  1
2001 Jones RB, Carstens RP, Luo Y, McKeehan WL. 5'- and 3'-terminal nucleotides in the FGFR2 ISAR splicing element core have overlapping roles in exon IIIb activation and exon IIIc repression. Nucleic Acids Research. 29: 3557-65. PMID 11522825  1
2001 Wu X, Kan M, Wang F, Jin C, Yu C, McKeehan WL. A rare premalignant prostate tumor epithelial cell syndecan-1 forms a fibroblast growth factor-binding complex with progression-promoting ectopic fibroblast growth factor receptor 1. Cancer Research. 61: 5295-302. PMID 11431373  1
2001 Liu Y, Ahmad H, Luo Y, Gardiner DT, Gunasekera RS, McKeehan WL, Patil BS. Citrus pectin: characterization and inhibitory effect on fibroblast growth factor-receptor interaction. Journal of Agricultural and Food Chemistry. 49: 3051-7. PMID 11410008  1
2001 Uematsu F, Jang JH, Kan M, Wang F, Luo Y, McKeehan WL. Evidence that the intracellular domain of FGF receptor 2IIIb affects contact of the ectodomain with two FGF7 ligands. Biochemical and Biophysical Research Communications. 283: 791-7. PMID 11350054 DOI: 10.1006/bbrc.2001.4850  1
2001 Jones RB, Wang F, Luo Y, Yu C, Jin C, Suzuki T, Kan M, McKeehan WL. The nonsense-mediated decay pathway and mutually exclusive expression of alternatively spliced FGFR2IIIb and -IIIc mRNAs. The Journal of Biological Chemistry. 276: 4158-67. PMID 11042206 DOI: 10.1074/jbc.M006151200  1
2000 Jang JH, Shin KH, Park YJ, Lee RJ, McKeehan WL, Park JG. Novel transcripts of fibroblast growth factor receptor 3 reveal aberrant splicing and activation of cryptic splice sequences in colorectal cancer. Cancer Research. 60: 4049-52. PMID 10945607  1
2000 Uematsu F, Kan M, Wang F, Jang JH, Luo Y, McKeehan WL. Ligand binding properties of binary complexes of heparin and immunoglobulin-like modules of FGF receptor 2. Biochemical and Biophysical Research Communications. 272: 830-6. PMID 10860838 DOI: 10.1006/bbrc.2000.2872  1
2000 Yu C, Wang F, Kan M, Jin C, Jones RB, Weinstein M, Deng CX, McKeehan WL. Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4. The Journal of Biological Chemistry. 275: 15482-9. PMID 10809780 DOI: 10.1074/jbc.275.20.15482  1
2000 Murakami S, Kan M, McKeehan WL, de Crombrugghe B. Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway. Proceedings of the National Academy of Sciences of the United States of America. 97: 1113-8. PMID 10655493 DOI: 10.1073/pnas.97.3.1113  1
2000 Reardon W, Smith A, Honour JW, Hindmarsh P, Das D, Rumsby G, Nelson I, Malcolm S, Adès L, Sillence D, Kumar D, DeLozier-Blanchet C, McKee S, Kelly T, McKeehan WL, et al. Evidence for digenic inheritance in some cases of Antley-Bixler syndrome? Journal of Medical Genetics. 37: 26-32. PMID 10633130  1
1999 Nakano K, Fukabori Y, Itoh N, Lu W, Kan M, McKeehan WL, Yamanaka H. Androgen-stimulated human prostate epithelial growth mediated by stromal-derived fibroblast growth factor-10. Endocrine Journal. 46: 405-13. PMID 10503993  1
1999 Nakano K, Taniguchi A, Kan M, McKeehan WL. Improved recovery of active radiolabeled TGFbeta1 by TGFbeta receptor type III affinity chromatography. In Vitro Cellular & Developmental Biology. Animal. 35: 241-3. PMID 10475267  1
1999 McKeehan WL, Wu X, Kan M. Requirement for anticoagulant heparan sulfate in the fibroblast growth factor receptor complex. The Journal of Biological Chemistry. 274: 21511-4. PMID 10419453 DOI: 10.1074/jbc.274.31.21511  1
1999 Kan M, Wu X, Wang F, McKeehan WL. Specificity for fibroblast growth factors determined by heparan sulfate in a binary complex with the receptor kinase. The Journal of Biological Chemistry. 274: 15947-52. PMID 10336501 DOI: 10.1074/jbc.274.22.15947  1
1999 Lu W, Luo Y, Kan M, McKeehan WL. Fibroblast growth factor-10. A second candidate stromal to epithelial cell andromedin in prostate. The Journal of Biological Chemistry. 274: 12827-34. PMID 10212269 DOI: 10.1074/jbc.274.18.12827  1
1999 Wang F, Lu W, McKeehan K, Mohamedali K, Gabriel JL, Kan M, McKeehan WL. Common and specific determinants for fibroblast growth factors in the ectodomain of the receptor kinase complex. Biochemistry. 38: 160-71. PMID 9890894 DOI: 10.1021/bi981758m  1
1998 Luo Y, Lu W, Mohamedali KA, Jang JH, Jones RB, Gabriel JL, Kan M, McKeehan WL. The glycine box: a determinant of specificity for fibroblast growth factor. Biochemistry. 37: 16506-15. PMID 9843417 DOI: 10.1021/bi9816599  1
1998 Date M, Matsuzaki K, Matsushita M, Sakitani K, Shibano K, Okajima A, Yamamoto C, Ogata N, Okumura T, Seki T, Kubota Y, Kan M, McKeehan WL, Inoue K. Differential expression of transforming growth factor-beta and its receptors in hepatocytes and nonparenchymal cells of rat liver after CCl4 administration. Journal of Hepatology. 28: 572-81. PMID 9566825 DOI: 10.1016/S0168-8278(98)80280-8  1
1998 Matsubara A, Kan M, Feng S, McKeehan WL. Inhibition of growth of malignant rat prostate tumor cells by restoration of fibroblast growth factor receptor 2. Cancer Research. 58: 1509-14. PMID 9537256  1
1998 Carstens RP, McKeehan WL, Garcia-Blanco MA. An intronic sequence element mediates both activation and repression of rat fibroblast growth factor receptor 2 pre-mRNA splicing. Molecular and Cellular Biology. 18: 2205-17. PMID 9528792  1
1998 McKeehan WL, Wang F, Kan M. The heparan sulfate-fibroblast growth factor family: diversity of structure and function. Progress in Nucleic Acid Research and Molecular Biology. 59: 135-76. PMID 9427842  1
1998 Luo Y, Lu W, Kan M, McKeehan WL, Albert B. Determinants of specificity within fibroblast growth factor (FGF)-7 for the fgf receptor-2iiib splice variant Faseb Journal. 12: A1301.  1
1998 Lu W, Luo Y, Kan M, McKeehan WL. Fibroblast growth factor-10 is an androgenresponsive paracrine growth factor in prostate Faseb Journal. 12: A1460.  1
1997 McKeehan WL, Wu X, Jang JH, Kan M. High salt inhibits both heparin-dependent and heparin-independent complexes of fibroblast growth factor and the receptor kinase. In Vitro Cellular & Developmental Biology. Animal. 33: 727-30. PMID 9466672  1
1997 Feng S, Wang F, Matsubara A, Kan M, McKeehan WL. Fibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells. Cancer Research. 57: 5369-78. PMID 9393762  1
1997 Wang F, Kan M, McKeehan K, Jang JH, Feng S, McKeehan WL. A homeo-interaction sequence in the ectodomain of the fibroblast growth factor receptor. The Journal of Biological Chemistry. 272: 23887-95. PMID 9295338 DOI: 10.1074/jbc.272.38.23887  1
1997 Zhou FY, Kan M, Owens RT, McKeehan WL, Thompson JA, Linhardt RJ, Höök M. Heparin-dependent fibroblast growth factor activities: effects of defined heparin oligosaccharides. European Journal of Cell Biology. 73: 71-80. PMID 9174673  1
1997 Myoken Y, Myoken Y, Okamoto T, Sato JD, Kan M, McKeehan WL, Fujihara M, Takada K. Immunohistochemical localization of fibroblast growth factor-1 (FGF-1), FGF-2 and fibroblast growth factor receptor-1 (FGFR-1) in pleomorphic adenoma of the salivary glands. Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 26: 17-22. PMID 9021547  1
1996 Feng S, Xu J, Wang F, Kan M, McKeehan WL. Nuclear localization of a complex of fibroblast growth factor(FGF)-1 and an NH2-terminal fragment of FGF receptor isoforms R4 and R1alpha in human liver cells. Biochimica Et Biophysica Acta. 1310: 67-73. PMID 9244177 DOI: 10.1016/0167-4889(95)00146-8  1
1996 Luo Y, Gabriel JL, Wang F, Zhan X, Maciag T, Kan M, McKeehan WL. Molecular modeling and deletion mutagenesis implicate the nuclear translocation sequence in structural integrity of fibroblast growth factor-1. The Journal of Biological Chemistry. 271: 26876-83. PMID 8900171 DOI: 10.1074/jbc.271.43.26876  1
1996 Matsuzaki K, Kan M, McKeehan WL. Reconstitution of a pentameric complex of dimeric transforming growth factor beta ligand and a type I, II, III receptor in baculoviral-infected insect cells. In Vitro Cellular & Developmental Biology. Animal. 32: 345-60. PMID 8842749  1
1996 Kan M, Wang F, To B, Gabriel JL, McKeehan WL. Divalent cations and heparin/heparan sulfate cooperate to control assembly and activity of the fibroblast growth factor receptor complex. The Journal of Biological Chemistry. 271: 26143-8. PMID 8824259 DOI: 10.1074/jbc.271.42.26143  1
1996 Wang F, McKeehan WL. Insulin-like growth factor-1 messenger RNA isoforms in rat prostate and prostate tumors. In Vitro Cellular & Developmental Biology. Animal. 32: 265-8. PMID 8792155 DOI: 10.1007/BF02723058  1
1996 Myoken Y, Myoken Y, Okamoto T, Sato JD, Kan M, McKeehan WL, Nakahara M, Takada K. Immunohistochemical study of overexpression of fibroblast growth factor-1 (FGF-1), FGF-2, and FGF receptor-1 in human malignant salivary gland tumours. The Journal of Pathology. 178: 429-36. PMID 8691322 DOI: 10.1002/(SICI)1096-9896(199604)178:4<429::AID-PATH495>3.0.CO;2-1  1
1996 Byrd V, Zhao XM, McKeehan WL, Miller GG, Thomas JW. Expression and functional expansion of fibroblast growth factor receptor T cells in rheumatoid synovium and peripheral blood of patients with rheumatoid arthritis. Arthritis and Rheumatism. 39: 914-22. PMID 8651984 DOI: 10.1002/art.1780390607  1
1996 Myoken Y, Myoken Y, Okamoto T, Kan M, McKeehan WL, Sato JD, Takada K. Expression of fibroblast growth factor-1 (FGF-1), FGF-2 and FGF receptor-1 in a human salivary-gland adenocarcinoma cell line: evidence of growth. International Journal of Cancer. Journal International Du Cancer. 65: 650-7. PMID 8598317 DOI: 10.1002/(SICI)1097-0215(19960301)65:5<650::AID-IJC15>3.0.CO;2-B  1
1995 Wang F, Kan M, McKeehan WL. Multiple mutant cDNAs from one reaction mixture using asymmetric primers in PCR. Biotechniques. 19: 556-9. PMID 8777043  1
1995 Xu J, McKeehan K, Matsuzaki K, McKeehan WL. Inhibin antagonizes inhibition of liver cell growth by activin by a dominant-negative mechanism Journal of Biological Chemistry. 270: 6308-6313. PMID 7890768 DOI: 10.1074/jbc.270.11.6308  1
1995 Wang F, Kan M, Yan G, Xu J, McKeehan WL. Alternately spliced NH2-terminal immunoglobulin-like Loop I in the ectodomain of the fibroblast growth factor (FGF) receptor 1 lowers affinity for both heparin and FGF-1. The Journal of Biological Chemistry. 270: 10231-5. PMID 7730327 DOI: 10.1074/jbc.270.17.10231  1
1995 Wang F, Kan M, Xu J, Yan G, McKeehan WL. Ligand-specific structural domains in the fibroblast growth factor receptor Journal of Biological Chemistry. 270: 10222-10230. PMID 7730326 DOI: 10.1074/jbc.270.17.10222  1
1995 Zhao XM, Byrd VM, McKeehan WL, Reich MB, Miller GG, Thomas JW. Costimulation of human CD4+ T cells by fibroblast growth factor-1 (acidic fibroblast growth factor). Journal of Immunology (Baltimore, Md. : 1950). 155: 3904-11. PMID 7561097  1
1994 Fujita Y, Okamoto T, Noshiro M, Mckeehan WL, Crabb JW, Whitney RG, Kato Y, Sato JD, Takada K. A Novel Heparin-Binding Protein, HBp15, Is Identified as Mammalian Ribosomal Protein L22 Biochemical and Biophysical Research Communications. 199: 706-713. PMID 8135813 DOI: 10.1006/bbrc.1994.1286  1
1994 Xu J, Matsuzaki K, Mckeehan K, Wang F, Kan M, Mckeehan WL. Genomic structure and cloned cDNAs predict that four variants in the kinase domain of serine/threonine kinase receptors arise by alternative splicing and poly(A) addition Proceedings of the National Academy of Sciences of the United States of America. 91: 7957-7961. PMID 8058741 DOI: 10.1073/pnas.91.17.7957  1
1994 Hou J, Wang F, McKeehan WL. Molecular cloning and expression of the gene for a major leucine-rich protein from human hepatoblastoma cells (HepG2) In Vitro Cellular & Developmental Biology - Animal: Journal of the Society For in Vitro Biology. 30: 111-114. PMID 8012652 DOI: 10.1007/BF02631402  1
1994 McKeehan WL, Kan M. Heparan sulfate fibroblast growth factor receptor complex: Structure- function relationships Molecular Reproduction and Development. 39: 69-82. PMID 7999363  1
1994 Fukabori Y, Yan G, Yamanaka H, McKeehan WL. Rapid induction of keratinocyte growth factor (FGF-7) and β-actin after exposure of prostate stromal cells to androgen In Vitro Cellular & Developmental Biology - Animal. 30: 745-746. PMID 7881627 DOI: 10.1007/BF02631296  1
1994 Prudovsky I, Savion N, Zhan X, Friesel R, Xu J, Hou J, McKeehan WL, Maciag T. Intact and functional fibroblast growth factor (FGF) receptor-1 trafficks near the nucleus in response to FGF-1. The Journal of Biological Chemistry. 269: 31720-4. PMID 7527394  1
1994 Zhang G, Sato JD, Herley MT, Tsang MWK, Ye H, Liu H, Ichimura T, Yan G, McKeehan WL, Stevens JL. Stable and temperature-sensitive transformation of rat kidney epithelial cells suppresses expression of acidic fibroblast growth factor 1 but activates secretion of fibroblast growth factor 3 (int-2) and vascular endothelial growth factor Cell Growth and Differentiation. 5: 349-357. PMID 7519042  1
1994 Gupta S, Kan M, Vemuru RP, Labrecque DR, McKeehan WL. Studies on the biological characterization and mitogenic interactions between hepatic stimulator substance and acidic fibroblast growth factor Cancer Letters. 78: 85-92. PMID 7514091 DOI: 10.1016/0304-3835(94)90035-3  1
1993 Kan M, Wang F, Xu J, Crabb JW, Hou J, McKeehan WL. An essential heparin-binding domain in the fibroblast growth factor receptor kinase Science. 259: 1918-1921. PMID 8456318  1
1993 Hou J, McKeehan K, Kan M, Carr SA, Huddleston MJ, Crabb JW, McKeehan WL. Identification of tyrosines 154 and 307 in the extracellular domain and 653 and 766 in the intracellular domain as phosphorylation sites in the heparin-binding fibroblast growth factor receptor tyrosine kinase (flg) Protein Science. 2: 86-92. PMID 8443592  1
1993 Matsuzaki K, Xu J, Wang F, McKeehan WL, Krummen L, Kan M. A widely expressed transmembrane serine/threonine kinase that does not bind activin, inhibin, transforming growth factor β, orbone morphogenic factor Journal of Biological Chemistry. 268: 12719-12723. PMID 8389764  1
1993 Yan G, McBride G, McKeehan WL. Exon skipping causes alteration of the COOH-terminus and deletion of the phospholipase Cγ1 interaction site in the FGF receptor 2 kinase in normal prostate epithelial cells Biochemical and Biophysical Research Communications. 194: 512-518. PMID 8333865 DOI: 10.1006/bbrc.1993.1849  1
1993 Shi E, Kan M, Xu J, Wang F, Hou J, McKeehan WL. Control of fibroblast growth factor receptor kinase signal transduction by heterodimerization of combinatorial splice variants Molecular and Cellular Biology. 13: 3907-3918. PMID 8321198  1
1993 McKeehan WL, Hou J, Adams P, Wang F, Yan GC, Kan M. Heparin-binding fibroblast growth factors and prostate cancer Advances in Experimental Medicine and Biology. 330: 203-213. PMID 7690178  1
1993 Yan G, Fukabori Y, McBride G, Nikolaropolous S, McKeehan WL. Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy Molecular and Cellular Biology. 13: 4513-4522. PMID 7687739  1
1993 Myoken Y, Kan M, Chen J, McKeehan WL, Sato GH, Sato JD. Monoclonal antibodies against heparin-binding growth factor-1: Neutralization of biological activity and recognition of specific amino acid sequence Biochemical and Biophysical Research Communications. 197: 1450-1457. PMID 7506543 DOI: 10.1006/bbrc.1993.2640  1
1992 Ding XY, McKeehan WL, Xu J, Grunz H. Spatial and temporal localization of FGF receptors in Xenopus laevis. Roux's Archives of Developmental Biology : the Official Organ of the Edbo. 201: 334-339. PMID 28305851 DOI: 10.1007/BF00365120  0.56
1992 Matuo Y, McKeehan WL, Yan GC, Nikolaropoulos S, Adams PS, Fukabori Y, Yamanaka H, Gaudreau J. Potential role of HBGF (FGF) and TGF-beta on prostate growth Advances in Experimental Medicine and Biology. 324: 107-114. PMID 1492611  1
1992 Yan G, Fukabori Y, Nikolaropoulos S, Wang F, McKeehan WL. Heparin-binding keratinocyte growth factor is a candidate stromal to epithelial cell andromedin Molecular Endocrinology. 6: 2123-2128. PMID 1491693  1
1992 Hou J, Kan M, Wang F, Xu JM, Nakahara M, McBride G, McKeehan K, McKeehan WL. Substitution of putative half-cystine residues in heparin-binding fibroblast growth factor receptors: Loss of binding activity in both two and three loop isoforms Journal of Biological Chemistry. 267: 17804-17808. PMID 1325450  1
1992 Xu J, Nakahara M, Crabb JW, Shi E, Matuo Y, Fraser M, Kan M, Hou J, McKeehan WL. Expression and immunochemical analysis of rat and human fibroblast growth factor receptor (flg) isoforms Journal of Biological Chemistry. 267: 17792-17803. PMID 1325449  1
1992 Yan G, Wang F, Fukabori Y, Sussman D, Hou J, McKeehan WL. Expression and transforming activity of a variant of the heparin-binding fibroblast growth factor receptor (flg) gene resulting from splicing of the alpha exon at an alternate 3′-acceptor site Biochemical and Biophysical Research Communications. 183: 423-430. PMID 1312829 DOI: 10.1016/0006-291X(92)90498-A  1
1992 Ding Xy, McKeehan WL, Xu J, Grunz H. Spatial and temporal localization of FGF receptors in Xenopus laevis Roux's Archives of Developmental Biology. 201: 334-339. DOI: 10.1007/BF00365120  1
1991 Chen JK, Hoshi H, McKeehan WL. Stimulation of human arterial smooth muscle cell chondroitin sulfate proteoglycan synthesis by transforming growth factor-beta In Vitro Cellular and Developmental Biology - Animal. 27: 6-12. PMID 2013555  1
1991 Shi E, Kan M, Xu J, McKeehan WL. 16-Kilodalton heparin binding (fibroblast) growth factor type one appears in a stable 40-kilodalton complex after receptor-dependent internalization Journal of Biological Chemistry. 266: 5774-5779. PMID 2005115  1
1991 Yan G, Nikolaropoulos S, Wang F, McKeehan WL. Sequence of rat keratinocyte growth factor (heparin-binding growth factor type 7) [3] In Vitro Cellular and Developmental Biology - Animal. 27: 437-438. PMID 1869483  1
1991 Hou J, Kan M, McKeehan K, McBridge G, Adams P, McKeehan WL. Fibroblast growth factor receptors from liver vary in three structural domains Science. 251: 665-668. PMID 1846977  1
1991 Kan M, Zhang G, Zarnegar R, Michalopoulos G, Myoken Y, McKeehan WL, Stevens JL. Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV-40 transformed RPTE Biochemical and Biophysical Research Communications. 174: 331-337. PMID 1846541 DOI: 10.1016/0006-291X(91)90524-B  1
1991 Kan M, Shi EG, McKeehan WL. Identification and assay of fibroblast growth factor receptors Methods in Enzymology. 198: 158-171. PMID 1713285 DOI: 10.1016/0076-6879(91)98017-Z  1
1991 McKeehan WL. Growth factor receptors and prostate cell growth Cancer Surveys. 11: 165-175. PMID 1668727  1
1990 McKeehan WL, Barnes D, Reid L, Stanbridge E, Murakami H, Sato GH. Frontiers in mammalian cell culture In Vitro Cellular and Developmental Biology - Animal. 26: 9-23. PMID 2407711  1
1990 Matuo Y, Nishi N, Takasuka H, Masuda Y, Nishikawa K, Isaacs JT, Adams PS, McKeehan WL, Sato GH. Production and significance of TGF-β in AT-3 metastatic cell line established from the Dunning rat prostatic adenocarcinoma Biochemical and Biophysical Research Communications. 166: 840-847. PMID 2302241 DOI: 10.1016/0006-291X(90)90886-R  1
1990 Myoken Y, Kan M, Sato GH, McKeehan WL, Sato JD. Bifunctional effects of transforming growth factor-β (TGF-β) on endothelial cell growth correlate with phenotypes of TGF-β binding sites Experimental Cell Research. 191: 299-304. PMID 1701723 DOI: 10.1016/0014-4827(90)90018-6  1
1990 Mansson PE, Malark M, Sawada H, Kan M, McKeehan WL. Heparin-binding (fibroblast) growth factors type one and two genes are co-expressed in proliferating normal human vascular endothelial and smooth muscle cells in culture In Vitro Cellular & Developmental Biology. 26: 209-212. PMID 1690207 DOI: 10.1007/BF02624114  1
1989 Spence AM, Sheppard PC, Davie JR, Matuo Y, Nishi N, McKeehan WL, Dodd JG, Matusik RJ. Regulation of a bifunctional mRNA results in synthesis of secreted and nuclear probasin. Proceedings of the National Academy of Sciences of the United States of America. 86: 7843-7. PMID 2682630  1
1989 Kan M, Huang J, Mansson PE, Yasumitsu H, Carr B, McKeehan WL. Heparin-binding growth factor type 1 (acidic fibroblast growth factor): A potential biphasic autocrine and paracrine regulator of hepatocyte regeneration Proceedings of the National Academy of Sciences of the United States of America. 86: 7432-7436. PMID 2477840  1
1989 Mansson PE, Adams P, Kan M, McKeehan WL. Heparin-binding growth factor gene expression and receptor characteristics in normal rat prostate and two transplantable rat prostate tumors Cancer Research. 49: 2485-2494. PMID 2468410  1
1988 McKeehan WL. Metabolic cooperativity within wounded tissue: hormone-nutrient interactions Progress in Clinical and Biological Research. 266: 177-181. PMID 3289041  1
1988 Hoshi H, Kan M, Chen JK, McKeehan WL. Comparative endocrinology-paracrinology-autocrinology of human adult large vessel endothelial and smooth muscle cells In Vitro Cellular & Developmental Biology. 24: 309-320. PMID 2835354 DOI: 10.1007/BF02628833  1
1988 Hoshi H, Kan M, Mioh H, Chen JK, McKeehan WL. Phorbol ester reduces number of heparin-binding growth-factor receptors in human adult endothelial cells Faseb Journal. 2: 2797-2800. PMID 2457532  1
1988 Kan M, DiSorbo D, Hou J, Hoshi H, Mansson PE, McKeehan WL. High and low affinity binding of heparin-binding growth factor to a 130-kDa receptor correlates with stimulation and inhibition of growth of a differentiated human hepatoma cell Journal of Biological Chemistry. 263: 11306-11313. PMID 2457020  1
1988 Grunz H, McKeehan WL, Knöchel W, Born J, Tiedemann H. Induction of mesodermal tissues by acidic and basic heparin binding growth factors Cell Differentiation. 22: 183-189. PMID 2451566 DOI: 10.1016/0045-6039(88)90010-3  1
1988 Chen JK, Hoshi H, McKeehan WL. Heparin-binding growth factor type one and platelet-derived growth factor are required for the optimal expression of cell surface low density lipoprotein receptor binding activity in human adult arterial smooth muscle cells In Vitro Cellular & Developmental Biology. 24: 199-204. PMID 2450862 DOI: 10.1007/BF02623547  1
1987 McKeehan WL, McKeehan KA. Kinetic analysis of cell growth factor-nutrient interactions Methods in Enzymology. 147: 392-400. PMID 3670094  1
1987 McKeehan WL, Adams PS, Fast D. Different hormonal requirements for androgen-independent growth of normal and tumor epithelial cells from rat prostate In Vitro Cellular & Developmental Biology. 23: 147-152. PMID 3546251 DOI: 10.1007/BF02623596  1
1987 Knöchel W, Born J, Hoppe P, Loppnow-Blinde B, Tiedemann H, McKeehan WL, Grunz H. Mesoderm-inducing factors - Their possible relationship to heparin-binding growth factors and transforming growth factor-β Naturwissenschaften. 74: 604-606. PMID 3481645 DOI: 10.1007/BF00368525  1
1987 Chen JK, Hoshi H, McKeehan WL. Transforming growth factor type β specifically stimulates synthesis of proteoglycan in human adult arterial smooth muscle cells Proceedings of the National Academy of Sciences of the United States of America. 84: 5287-5291. PMID 3474655  1
1987 McKeehan WL, McKeehan KA. Isolation of two proteinase inhibitors from human hepatoma cells that stimulate human endothelial cell growth Methods in Enzymology. 147: 152-156. PMID 2823051  1
1987 Barnes D, McKeehan WL, Sato GH. Cellular endocrinology: Integrated physiology in vitro In Vitro Cellular & Developmental Biology. 23: 659-662. PMID 2822650 DOI: 10.1007/BF02620978  1
1987 McKeehan WL, Crabb JW. Isolation and characterization of different molecular and chromatographic forms of heparin-binding growth factor 1 from bovine brain Analytical Biochemistry. 164: 563-569. PMID 2445228 DOI: 10.1016/0003-2697(87)90534-3  1
1987 Hoshi H, Kan M, McKeehan WL. Direct analysis of growth factor requirements for isolated human fetal hepatocytes In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 23: 723-732. PMID 2444574  1
1986 Crabb JW, Armes LG, Carr SA, Johnson CM, Roberts GD, Bordoli RS, McKeehan WL. Complete primary structure of prostatropin, a prostate epithelial cell growth factor 1 Biochemistry. 25: 4988-4993. PMID 3768327  1
1986 Crabb JW, Armes LG, Johnson CM, McKeehan WL. Characterization of multiple forms of prostatropin (prostate epithelial cell growth factor) from bovine brain Biochemical and Biophysical Research Communications. 136: 1155-1161. PMID 3755043 DOI: 10.1016/0006-291X(86)90455-9  1
1986 Chen JK, Hoshi H, McClure DB, McKeehan WL. Role of lipoproteins in growth of human adult arterial endothelial and smooth muscle cells in low lipoprotein-deficient serum Journal of Cellular Physiology. 129: 207-214. PMID 3533960  1
1986 Bettger WJ, McKeehan WL. Mechanisms of cellular nutrition Physiological Reviews. 66: 1-35. PMID 3511479  1
1986 Hoshi H, McKeehan WL. Isolation, growth requirements, cloning, prostacyclin production and life-span of human adult endothelial cells in low serum culture medium In Vitro Cellular & Developmental Biology. 22: 51-56. PMID 3080403 DOI: 10.1007/BF02623441  1
1986 McKeehan WL, Sakagami Y, Hoshi H, McKeehan KA. Two apparent human endothelial cell growth factors from human hepatoma cells are tumor-associated proteinase inhibitors Journal of Biological Chemistry. 261: 5378-5383. PMID 3007499  1
1986 Chaproniere DM, McKeehan WL. Serial culture of single adult human prostatic epithelial cells in serum-free medium containing low calcium and a new growth factor from bovine brain Cancer Research. 46: 819-824. PMID 3000587  1
1986 McKeehan WL, Adams PS. Assay of growth factors for prostate epithelial cells Journal of Tissue Culture Methods. 10: 151-154. DOI: 10.1007/BF01404605  1
1985 Hoshi H, McKeehan WL. Production of an auto-stimulatory growth factor by human hepatoma cells abrogates requirement for a brain-derived factor In Vitro Cellular & Developmental Biology. 21: 125-128. PMID 2989242 DOI: 10.1007/BF02620954  1
1984 McKeehan WL. Control of normal and transformed cell proliferation by growth factor-nutrient interactions Federation Proceedings. 43: 113-115. PMID 6690330  1
1984 McKeehan WL, Adams PS, Rosser MP. Direct mitogenic effects of insulin, epidermal growth factor, glucocorticoid, cholera toxin, unknown pituitary factors and possibly prolactin, but not androgen, on normal rat prostate epithelial cells in serum-free, primary cell culture. Cancer Research. 44: 1998-2010. PMID 6370422  1
1984 Hoshi H, McKeehan WL. Brain- and liver cell-derived factors are required for growth of human endothelial cells in serum-free culture Proceedings of the National Academy of Sciences of the United States of America. 81: 6413-6417. PMID 6333682  1
1982 McKeehan WL, Glass HA, Rosser MP, Adams PS. Prostatic binding protein, polyamine, and DNA synthesis in rat ventral prostate cells. The Prostate. 3: 231-46. PMID 7201637  1
1982 McKeehan WL, McKeehan KA. Changes in NAD(P)+-dependent malic enzyme and malate dehydrogenase activities during fibroblast proliferation Journal of Cellular Physiology. 110: 142-148. PMID 7068771  1
1982 McKeehan WL, Adams PS, Rosser MP. Modified nutrient medium MCDB 151, defined growth factors, cholera toxin, pituitary factors, and horse serum support epithelial cell and suppress fibroblast proliferation in primary cultures of rat ventral prostate cells. In Vitro. 18: 87-91. PMID 7044957 DOI: 10.1007/BF02796399  1
1982 McKeehan WL, McKeehan KA, Calkins D. Epidermal growth factor modifies Ca2+, Mg2+ and 2-oxocarboxylic acid, but not K+ and phosphate ion requirement for multiplication of human fibroblasts Experimental Cell Research. 140: 25-30. PMID 6980792 DOI: 10.1016/0014-4827(82)90151-3  1
1982 McKeehan WL. Glycolysis, glutaminolysis and cell proliferation Cell Biology International Reports. 6: 635-650. PMID 6751566 DOI: 10.1016/0309-1651(82)90125-4  1
1982 McKeehan WL, Adams PS, Rosser MP. Modified nutrient medium MCDB 151, defined growth factors, cholera toxin, pituitary factors, and horse serum support epithelial cell and suppress fibroblast proliferation in primary cultures of rat ventral prostate cells In Vitro. 18: 418. DOI: 10.1007/BF02796344  1
1981 McKeehan WL, McKeehan KA. Extracellular regulation of fibroblast multiplication: A direct kinetic approach to analysis of role of low molecular weight nutrients and serum growth factor Journal of Supramolecular and Cellular Biochemistry. 15: 83-110. PMID 7253650  1
1981 McKeehan WL, Fast D, Jones WA. The major androgen-dependent protein in rat ventral prostate binds polycyclic aromatic hydrocarbons Cell Biology International Reports. 5: 2. PMID 7226237 DOI: 10.1016/0309-1651(81)90150-8  1
1981 McKeehan WL, McKeehan KA, Calkins D. Extracellular regulation of fibroblast multiplication. Quantitative differences in nutrient and serum factor requirements for multiplication of normal and SV40 virus-transformed human lung cells Journal of Biological Chemistry. 256: 2973. PMID 6259146  1
1981 McKeehan WL, McKeehan KA. Simple radiometric assay for aminoacid:2-oxoacid aminotransferases and 2-hydroxyacid:2-oxoacid oxidoreductases Bioscience Reports. 1: 661-668. DOI: 10.1007/BF01116282  1
1980 McKeehan WL, Rosser MP, Glass HA, Fast D. Prostatic binding protein: an androgen-dependent marker for prostate epithelial cells. Biochemical and Biophysical Research Communications. 95: 674-81. PMID 6998468  1
1980 McKeehan WL, McKeehan KA. Serum factors modify the cellular requirement for Ca2+, K+, Mg2+, phosphate ions, and 2-oxocarboxylic acids for multiplication of normal human fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 77: 3417-3421. PMID 6932028  1
1980 McKeehan WL, McKeehan KA. Calcium, magnesium, and serum factors in multiplication of normal and transformed human lung fibroblasts In Vitro. 16: 475-485. PMID 6248455 DOI: 10.1007/BF02626460  1
1979 McKeehan WL, McKeehan KA. Oxocarboxylic acids, pyridine nucleotide-linked oxidoreductases and serum factors in regulation of cell proliferation Journal of Cellular Physiology. 101: 9-16. PMID 575536  1
1971 Obrig TG, Culp WJ, McKeehan WL, Hardesty B. The mechanism by which cycloheximide and related glutarimide antibiotics inhibit peptide synthesis on reticulocyte ribosomes. The Journal of Biological Chemistry. 246: 174-81. PMID 5541758  1
1969 Lin SY, McKeehan WL, Culp W, Hardesty B. Partial characterization of the enzymatic properties of the aminoacyl transfer ribonucleic acid binding enzyme. The Journal of Biological Chemistry. 244: 4340-50. PMID 5806580  1
1969 Culp WJ, McKeehan WL, Hardesty B. Deacylated tRNA-phe binding to a reticulocyte ribosomal site for the initiation of polyphenylalanine synthesis. Proceedings of the National Academy of Sciences of the United States of America. 63: 1431-8. PMID 5260946  1
1969 McKeehan WL, Hardesty B. Purification and partial characterization of the aminoacyl transfer ribonucleic acid binding enzyme from rabbit reticulocytes. The Journal of Biological Chemistry. 244: 4330-9. PMID 4308855  1
Show low-probability matches.