Ralph J. Abi-Habib, Ph.D. - Publications

Affiliations: 
2005 Wake Forest University, Winston-Salem, NC, United States 
Area:
Oncology, Biochemistry, Molecular Biology

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 El-Mais N, Fakhoury I, Al Haddad M, Nohra S, Abi-Habib R, El-Sibai M. Human Recombinant Arginase I [HuArgI(Co)-PEG5000]-Induced Arginine Depletion Inhibits Pancreatic Cancer Cell Migration and Invasion Through Autophagy. Pancreas. 50: 1187-1194. PMID 34714283 DOI: 10.1097/MPA.0000000000001891  0.346
2021 El-Chami D, Al Haddad M, Abi-Habib R, El-Sibai M. Recombinant anthrax lethal toxin inhibits cell motility and invasion in breast cancer cells through the dysregulation of Rho GTPases. Oncology Letters. 21: 163. PMID 33552281 DOI: 10.3892/ol.2020.12424  0.313
2021 El-Mais N, Fakhoury I, Abdellatef S, Abi-Habib R, El-Sibai M. Human recombinant arginase I [HuArgI (Co)-PEG5000]-induced arginine depletion inhibits ovarian cancer cell adhesion and migration through autophagy-mediated inhibition of RhoA. Journal of Ovarian Research. 14: 13. PMID 33423701 DOI: 10.1186/s13048-021-00767-3  0.39
2020 Swayden M, Bekdash A, Fakhoury I, El-Atat O, Borjac-Natour J, El-Sibai M, Abi-Habib RJ. Activation of autophagy following [HuArgI (Co)-PEG5000]-induced arginine deprivation mediates cell death in colon cancer cells. Human Cell. PMID 32979152 DOI: 10.1007/s13577-020-00437-4  0.473
2020 Al-Koussa H, El Mais N, Maalouf H, Abi-Habib R, El-Sibai M. Arginine deprivation: a potential therapeutic for cancer cell metastasis? A review. Cancer Cell International. 20: 150. PMID 32390765 DOI: 10.1186/S12935-020-01232-9  0.375
2019 Khalil N, Abi-Habib RJ. [HuArgI (co)-PEG5000]-induced arginine deprivation leads to autophagy dependent cell death in pancreatic cancer cells. Investigational New Drugs. PMID 31823161 DOI: 10.1007/S10637-019-00883-4  0.552
2019 Al-Koussa H, Al-Haddad M, Abi-Habib R, El-Sibai M. Human Recombinant Arginase I [HuArgI (Co)-PEG5000]-Induced Arginine Depletion Inhibits Colorectal Cancer Cell Migration and Invasion. International Journal of Molecular Sciences. 20. PMID 31795337 DOI: 10.3390/Ijms20236018  0.376
2019 Nasreddine G, El-Sibai M, Abi-Habib RJ. Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent. Investigational New Drugs. PMID 30887252 DOI: 10.1007/S10637-019-00756-W  0.558
2018 Audi H, Azar DF, Mahjoub F, Farhat S, El Masri Z, El-Sibai M, Abi-Habib RJ, Khnayzer RS. Cytotoxicity modulation of ruthenium(II) tris-bathophenanthroline complexes with systematically varied charge Journal of Photochemistry and Photobiology a: Chemistry. 351: 59-68. DOI: 10.1016/J.Jphotochem.2017.10.007  0.336
2016 Al-Dimassi S, Salloum G, Saykali B, Khoury O, Liu S, Leppla SH, Abi-Habib R, El-Sibai M. Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion. International Journal of Oncology. PMID 26984023 DOI: 10.3892/Ijo.2016.3431  0.523
2016 Boulos J, Abi-Habib R, El-Sibai M, Shebaby W, Daher C, Taleb R, Mroueh M. A new sesquiterpene from Lebanese wild carrot inhibits proliferation of human acute myeloid leukemia cells Planta Medica. 81: S1-S381. DOI: 10.1055/S-0036-1596492  0.451
2015 Bekdash A, Darwish M, Timsah Z, Kassab E, Ghanem H, Najjar V, Ghosn M, Nasser S, El-Hajj H, Bazerbachi A, Liu S, Leppla SH, Frankel AE, Abi-Habib RJ. Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF). Translational Oncology. 8: 347-57. PMID 26500025 DOI: 10.1016/J.Tranon.2015.07.001  0.664
2015 Tawil M, Bekdash A, Mroueh M, Daher CF, Abi-Habib RJ. Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells. Asian Pacific Journal of Cancer Prevention : Apjcp. 16: 761-7. PMID 25684522 DOI: 10.7314/Apjcp.2015.16.2.761  0.53
2015 Khoury O, Ghazale N, Stone E, El-Sibai M, Frankel AE, Abi-Habib RJ. Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells. Journal of Neuro-Oncology. 122: 75-85. PMID 25567351 DOI: 10.1016/S0959-8049(14)50671-5  0.668
2014 Bekdash A, Liu S, Leppla S, Frankel A, Abi-Habib R. 394 Sensitivity of acute myeloid leukemia cells to a urokinase-activated anthrax lethal toxin (PrAgU2/lf) is dependent on uPAR expression and phospho-MEK1/2 levels European Journal of Cancer. 50: 126. DOI: 10.1016/S0959-8049(14)70520-9  0.379
2013 Tanios R, Bekdash A, Kassab E, Stone E, Georgiou G, Frankel AE, Abi-Habib RJ. Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells. Leukemia Research. 37: 1565-71. PMID 24018014 DOI: 10.1016/J.Leukres.2013.08.007  0.669
2013 Kassab E, Darwish M, Timsah Z, Liu S, Leppla SH, Frankel AE, Abi-Habib RJ. Cytotoxicity of anthrax lethal toxin to human acute myeloid leukemia cells is nonapoptotic and dependent on extracellular signal-regulated kinase 1/2 activity. Translational Oncology. 6: 25-32. PMID 23418614 DOI: 10.1593/Tlo.12313  0.659
2012 Abi-Habib R, Kassab E, Darwish M, Timsah Z, Liu S, Leppla S, Frankel A. 326 Acute Myeloid Leukemia (AML) Cell Lines Are Sensitive to the Anthrax Lethal Toxin (LeTx)-Mediated Inhibition of the MAPK Pathway European Journal of Cancer. 48: 100. DOI: 10.1016/S0959-8049(12)72124-X  0.427
2009 Pommerville P, Egerdie B, Denmeade S, Merchant R, Buckley T, Abi-Habib R. 359 A PSA-ACTIVATED PROTO XIN (PRX302) ADMINISTERED TRANSPERINEALLY TO MEN WITH SYMPTOMATIC BENIGN PROSTATIC HYPERPLASIA IS WELL TOLERATED AND EXHIBITS SUSTAINED SIGNS OF ACTIVITY European Urology Supplements. 8: 210. DOI: 10.1016/S1569-9056(09)60362-6  0.307
2007 Singh R, Browning JL, Abi-Habib R, Wong K, Williams SA, Merchant R, Denmeade SR, Buckley TJ, Frankel AE. Recombinant prostate-specific antigen proaerolysin shows selective protease sensitivity and cell cytotoxicity. Anti-Cancer Drugs. 18: 809-16. PMID 17581303 DOI: 10.1097/Cad.0B013E3280Bad82D  0.549
2006 Abi-Habib RJ, Singh R, Leppla SH, Greene JJ, Ding Y, Berghuis B, Duesbery NS, Frankel AE. Systemic anthrax lethal toxin therapy produces regressions of subcutaneous human melanoma tumors in athymic nude mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 7437-43. PMID 17189417 DOI: 10.1158/1078-0432.Ccr-06-2019  0.615
2006 Abi-Habib RJ, Singh R, Liu S, Bugge TH, Leppla SH, Frankel AE. A urokinase-activated recombinant anthrax toxin is selectively cytotoxic to many human tumor cell types. Molecular Cancer Therapeutics. 5: 2556-62. PMID 17041100 DOI: 10.1158/1535-7163.Mct-06-0315  0.624
2005 Abi-Habib RJ, Urieto JO, Liu S, Leppla SH, Duesbery NS, Frankel AE. BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin. Molecular Cancer Therapeutics. 4: 1303-10. PMID 16170021 DOI: 10.1158/1535-7163.Mct-05-0145  0.687
2005 Frankel AE, Abi-Habib RJ, Urieto JO, Liu S, Leppla SH, van de Woude GF, Duesbery NS. Anthrax tumor toxin (LeTx) selectively kills B-RAF mutant melanomas Journal of Clinical Oncology. 23: 7533-7533. DOI: 10.1200/Jco.2005.23.16_Suppl.7533  0.591
2004 Westcott MM, Abi-Habib RJ, Cohen KA, Willingham MC, Liu S, Bugge TH, Leppla SH, Frankel AE. Diphtheria toxin-murine granulocyte-macrophage colony-stimulating factor-induced hepatotoxicity is mediated by Kupffer cells. Molecular Cancer Therapeutics. 3: 1681-9. PMID 15634662  0.576
2004 Abi-Habib RJ, Liu S, Bugge TH, Leppla SH, Frankel AE. A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia blasts. Blood. 104: 2143-8. PMID 15161668 DOI: 10.1182/Blood-2004-01-0339  0.655
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