Alayna E. Loiselle, Ph.D. - Publications

Affiliations: 
2009 University of Rochester, Rochester, NY 
Area:
Pathology, Physiology Biology

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Geary MB, Orner CA, Shammas H, Reuter JM, Loiselle AE, Giordano BD, Wu CL. The surgical destabilization of the abductor muscle leads to development of instability-associated hip osteoarthritis in mice. Journal of Hip Preservation Surgery. 10: 158-165. PMID 38162262 DOI: 10.1093/jhps/hnad015  0.324
2023 Ackerman JE, Muscat SN, Adjei-Sowah E, Korcari A, Nichols AEC, Buckley MR, Loiselle AE. Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing. Matrix Biology : Journal of the International Society For Matrix Biology. PMID 38101460 DOI: 10.1016/j.matbio.2023.12.004  0.337
2023 Ackerman JE, Adjei-Sowah E, Korcari A, Muscat SN, Nichols AEC, Buckley MR, Loiselle AE. Identification of Periostin as a critical niche for myofibroblast dynamics and fibrosis during tendon healing. Biorxiv : the Preprint Server For Biology. PMID 37502924 DOI: 10.1101/2023.07.21.550090  0.337
2022 Muscat S, Nichols AEC, Gira E, Loiselle AE. CCR2 is expressed by tendon resident macrophage and T cells, while CCR2 deficiency impairs tendon healing via blunted involvement of tendon-resident and circulating monocytes/macrophages. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 36: e22607. PMID 36250393 DOI: 10.1096/fj.202201162R  0.351
2022 Korcari A, Muscat S, McGinn E, Buckley MR, Loiselle AE. Depletion of Scleraxis-lineage cells during tendon healing transiently impairs multi-scale restoration of tendon structure during early healing. Plos One. 17: e0274227. PMID 36240193 DOI: 10.1371/journal.pone.0274227  0.302
2022 Kallenbach JG, Freeberg MAT, Abplanalp D, Alenchery RG, Ajalik RE, Muscat S, Myers JA, Ashton JM, Loiselle A, Buckley MR, van Wijnen AJ, Awad HA. Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse. Scientific Reports. 12: 3026. PMID 35194136 DOI: 10.1038/s41598-022-07124-4  0.364
2021 Best KT, Korcari A, Mora KE, Nichols AE, Muscat SN, Knapp E, Buckley MR, Loiselle AE. Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis. Elife. 10. PMID 33480357 DOI: 10.7554/eLife.62203  0.327
2020 Best KT, Studentsova V, Ackerman JE, Nichols AEC, Myers M, Cobb J, Knapp E, Awad HA, Loiselle AE. Effects of Tamoxifen on Tendon Homeostasis and Healing: Considerations for the use of Tamoxifen-Inducible Mouse Models. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 32485026 DOI: 10.1002/Jor.24767  0.358
2019 Best KT, Lee FK, Knapp E, Awad HA, Loiselle AE. Deletion of NFKB1 enhances canonical NF-κB signaling and increases macrophage and myofibroblast content during tendon healing. Scientific Reports. 9: 10926. PMID 31358843 DOI: 10.1038/S41598-019-47461-5  0.386
2019 Ackerman JE, Studentsova V, Myers M, Buckley MR, Richards MS, Loiselle AE. Non-invasive ultrasound quantification of Scar Tissue Volume identifies early functional changes during tendon healing. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 31231903 DOI: 10.1002/Jor.24397  0.445
2019 Nichols AEC, Oh I, Loiselle AE. The Effects of Type II Diabetes Mellitus on Tendon Homeostasis and Healing. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 31166037 DOI: 10.1002/Jor.24388  0.325
2019 Ackerman JE, Nichols AE, Studentsova V, Best KT, Knapp E, Loiselle AE. Cell non-autonomous functions of S100a4 drive fibrotic tendon healing. Elife. 8. PMID 31124787 DOI: 10.7554/Elife.45342  0.445
2019 Feigenson M, Jonason JH, Shen J, Loiselle AE, Awad HA, O'Keefe RJ. Inhibition of the Prostaglandin EP-1 Receptor in Periosteum Progenitor Cells Enhances Osteoblast Differentiation and Fracture Repair. Annals of Biomedical Engineering. PMID 30980293 DOI: 10.1007/S10439-019-02264-7  0.599
2019 Best KT, Loiselle AE. Scleraxis lineage cells contribute to organized bridging tissue during tendon healing and identify a subpopulation of resident tendon cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900130RR. PMID 30951381 DOI: 10.1096/Fj.201900130Rr  0.397
2019 Studentsova V, Knapp E, Loiselle AE. Insulin Receptor deletion in S100a4-lineage cells accelerates age-related bone loss. Bone Reports. 10: 100197. PMID 30805422 DOI: 10.1016/J.Bonr.2019.100197  0.445
2019 Nichols AEC, Best KT, Loiselle AE. The cellular basis of fibrotic tendon healing: challenges and opportunities. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 30776336 DOI: 10.1016/J.Trsl.2019.02.002  0.438
2019 Ackerman JE, Nichols AE, Studentsova V, Best KT, Knapp E, Loiselle AE. Author response: Cell non-autonomous functions of S100a4 drive fibrotic tendon healing Elife. DOI: 10.7554/Elife.45342.023  0.34
2018 Studentsova V, Mora KM, Glasner MF, Buckley MR, Loiselle AE. Obesity/Type II Diabetes Promotes Function-limiting Changes in Murine Tendons that are not reversed by Restoring Normal Metabolic Function. Scientific Reports. 8: 9218. PMID 29907811 DOI: 10.1038/S41598-018-27634-4  0.311
2018 Loiselle AE, Zuscik MJ. Skeletal Healing: Cellular and Molecular Determinants Primer On the Metabolic Bone Diseases and Disorders of Mineral Metabolism. 101-107. DOI: 10.1002/9781119266594.Ch13  0.324
2017 Ackerman JE, Best KT, O'Keefe RJ, Loiselle AE. Deletion of EP4 in S100a4-lineage cells reduces scar tissue formation during early but not later stages of tendon healing. Scientific Reports. 7: 8658. PMID 28819185 DOI: 10.1038/S41598-017-09407-7  0.615
2017 Ackerman JE, Geary MB, Orner CA, Bawany F, Loiselle AE. Obesity/Type II diabetes alters macrophage polarization resulting in a fibrotic tendon healing response. Plos One. 12: e0181127. PMID 28686669 DOI: 10.1371/Journal.Pone.0181127  0.394
2017 Ackerman JE, Bah I, Jonason JH, Buckley MR, Loiselle AE. Aging Does Not Alter Tendon Mechanical Properties During Homeostasis, but does Impair Flexor Tendon Healing. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 28419543 DOI: 10.1002/Jor.23580  0.403
2017 Kelly M, Loiselle A, Zuscik M, Giordano BD. Estrogen Deprivation and Diet-Induced Obesity Result in Alterations in Bone and Cartilage Content in the Murine Hip Orthopaedic Journal of Sports Medicine. 5: 2325967117S0041. DOI: 10.1177/2325967117S00413  0.357
2016 Ackerman JE, Loiselle AE. Murine Flexor Tendon Injury and Repair Surgery. Journal of Visualized Experiments : Jove. PMID 27684281 DOI: 10.3791/54433  0.473
2016 Orner CA, Geary MB, Hammert WC, O'Keefe RJ, Loiselle AE. Low-Dose and Short-Duration Matrix Metalloproteinase 9 Inhibition Does Not Affect Adhesion Formation during Murine Flexor Tendon Healing. Plastic and Reconstructive Surgery. 137: 545e-53e. PMID 26910699 DOI: 10.1097/01.Prs.0000475823.01907.53  0.619
2015 Loiselle AE, Kelly M, Hammert WC. Biological Augmentation of Flexor Tendon Repair: A Challenging Cellular Landscape. The Journal of Hand Surgery. PMID 26652792 DOI: 10.1016/J.Jhsa.2015.07.002  0.449
2015 Geary MB, Orner CA, Bawany F, Awad HA, Hammert WC, O'Keefe RJ, Loiselle AE. Systemic EP4 Inhibition Increases Adhesion Formation in a Murine Model of Flexor Tendon Repair. Plos One. 10: e0136351. PMID 26312751 DOI: 10.1371/Journal.Pone.0136351  0.629
2015 Loiselle AE, Yukata K, Geary MB, Kondabolu S, Shi S, Jonason JH, Awad HA, O'Keefe RJ. Development of antisense oligonucleotide (ASO) technology against Tgf-β signaling to prevent scarring during flexor tendon repair. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 859-66. PMID 25761254 DOI: 10.1002/Jor.22890  0.538
2015 Zhang M, Feigenson M, Sheu TJ, Awad HA, Schwarz EM, Jonason JH, Loiselle AE, O'Keefe RJ. Loss of the PGE2 receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength. Bone. 72: 92-100. PMID 25446888 DOI: 10.1016/J.Bone.2014.11.018  0.665
2015 Lee DJ, Southgate RD, Farhat YM, Loiselle AE, Hammert WC, Awad HA, O'Keefe RJ. Parathyroid hormone 1-34 enhances extracellular matrix deposition and organization during flexor tendon repair. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 17-24. PMID 25266795 DOI: 10.1002/Jor.22735  0.648
2014 Govey PM, Jacobs JM, Tilton SC, Loiselle AE, Zhang Y, Freeman WM, Waters KM, Karin NJ, Donahue HJ. Integrative transcriptomic and proteomic analysis of osteocytic cells exposed to fluid flow reveals novel mechano-sensitive signaling pathways. Journal of Biomechanics. 47: 1838-45. PMID 24720889 DOI: 10.1016/J.Jbiomech.2014.03.022  0.306
2014 Lloyd SA, Loiselle AE, Zhang Y, Donahue HJ. Evidence for the role of connexin 43-mediated intercellular communication in the process of intracortical bone resorption via osteocytic osteolysis. Bmc Musculoskeletal Disorders. 15: 122. PMID 24716486 DOI: 10.1186/1471-2474-15-122  0.438
2014 Lloyd SA, Loiselle AE, Zhang Y, Donahue HJ. Shifting paradigms on the role of connexin43 in the skeletal response to mechanical load. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 275-86. PMID 24588015 DOI: 10.1002/Jbmr.2165  0.429
2013 Loiselle AE, Lloyd SA, Paul EM, Lewis GS, Donahue HJ. Inhibition of GSK-3β rescues the impairments in bone formation and mechanical properties associated with fracture healing in osteoblast selective connexin 43 deficient mice. Plos One. 8: e81399. PMID 24260576 DOI: 10.1371/Journal.Pone.0081399  0.48
2013 Lloyd SA, Loiselle AE, Zhang Y, Donahue HJ. Connexin 43 deficiency desensitizes bone to the effects of mechanical unloading through modulation of both arms of bone remodeling. Bone. 57: 76-83. PMID 23891909 DOI: 10.1016/J.Bone.2013.07.022  0.449
2013 Govey PM, Loiselle AE, Donahue HJ. Biophysical regulation of stem cell differentiation. Current Osteoporosis Reports. 11: 83-91. PMID 23532405 DOI: 10.1007/S11914-013-0138-3  0.384
2013 Loiselle AE, Wei L, Faryad M, Paul EM, Lewis GS, Gao J, Lakhtakia A, Donahue HJ. Specific biomimetic hydroxyapatite nanotopographies enhance osteoblastic differentiation and bone graft osteointegration. Tissue Engineering. Part A. 19: 1704-12. PMID 23510012 DOI: 10.1089/Ten.Tea.2012.0560  0.429
2013 Loiselle AE, Jiang JX, Donahue HJ. Gap junction and hemichannel functions in osteocytes. Bone. 54: 205-12. PMID 23069374 DOI: 10.1016/J.Bone.2012.08.132  0.424
2013 Loiselle AE, Paul EM, Lewis GS, Donahue HJ. Osteoblast and osteocyte-specific loss of Connexin43 results in delayed bone formation and healing during murine fracture healing. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 31: 147-54. PMID 22718243 DOI: 10.1002/Jor.22178  0.475
2012 Loiselle AE, Frisch BJ, Wolenski M, Jacobson JA, Calvi LM, Schwarz EM, Awad HA, O'Keefe RJ. Bone marrow-derived matrix metalloproteinase-9 is associated with fibrous adhesion formation after murine flexor tendon injury. Plos One. 7: e40602. PMID 22792383 DOI: 10.1371/Journal.Pone.0040602  0.638
2011 Lim JY, Loiselle AE, Lee JS, Zhang Y, Salvi JD, Donahue HJ. Optimizing the osteogenic potential of adult stem cells for skeletal regeneration. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 1627-33. PMID 21509820 DOI: 10.1002/Jor.21441  0.311
2011 Katzel EB, Wolenski M, Loiselle AE, Basile P, Flick LM, Langstein HN, Hilton MJ, Awad HA, Hammert WC, O'Keefe RJ. Impact of Smad3 loss of function on scarring and adhesion formation during tendon healing. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 684-93. PMID 20842701 DOI: 10.1002/Jor.21235  0.639
2010 Gunnell LM, Jonason JH, Loiselle AE, Kohn A, Schwarz EM, Hilton MJ, O'Keefe RJ. TAK1 regulates cartilage and joint development via the MAPK and BMP signaling pathways. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1784-97. PMID 20213696 DOI: 10.1002/Jbmr.79  0.532
2009 Xie C, Liang B, Xue M, Lin AS, Loiselle A, Schwarz EM, Guldberg RE, O'Keefe RJ, Zhang X. Rescue of impaired fracture healing in COX-2-/- mice via activation of prostaglandin E2 receptor subtype 4. The American Journal of Pathology. 175: 772-85. PMID 19628768 DOI: 10.2353/Ajpath.2009.081099  0.615
2009 Loiselle AE, Bragdon GA, Jacobson JA, Hasslund S, Cortes ZE, Schwarz EM, Mitten DJ, Awad HA, O'Keefe RJ. Remodeling of murine intrasynovial tendon adhesions following injury: MMP and neotendon gene expression. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 27: 833-40. PMID 19051246 DOI: 10.1002/Jor.20769  0.626
2008 Loiselle AE, O'Keefe RJ. Differential Mmp response to PGE2 during flexor tendon healing Matrix Biology. 27: 42. DOI: 10.1016/J.Matbio.2008.09.350  0.555
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