Matthew Bogyo - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Biochemistry, Cell Biology

94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Babin BM, Kasperkiewicz P, Janiszewski T, Yoo E, Drag M, Bogyo M. Leveraging peptide substrate libraries to design inhibitors of bacterial Lon protease. Acs Chemical Biology. PMID 31464417 DOI: 10.1021/acschembio.9b00529  0.48
2019 de Vries LE, Sanchez MI, Groborz K, Kuppens L, Poreba M, Lehmann C, Nevins N, Withers-Martinez C, Hirst DJ, Yuan F, Arastu-Kapur S, Horn M, Mares M, Bogyo M, Drag M, et al. Characterization of P. falciparum dipeptidyl aminopeptidase 3 specificity identifies differences in amino acid preferences between peptide-based substrates and covalent inhibitors. The Febs Journal. PMID 31177613 DOI: 10.1111/febs.14953  0.48
2016 Lentz CS, Ordonez AA, Kasperkiewicz P, La Greca F, O'Donoghue AJ, Schulze CJ, Powers JC, Craik CS, Drag M, Jain SK, Bogyo M. Design of Selective Substrates and Activity-Based Probes for Hydrolase Important for Pathogenesis 1 (HIP1) from Mycobacterium tuberculosis. Acs Infectious Diseases. PMID 27739665 DOI: 10.1021/acsinfecdis.6b00092  0.48
2016 Grüner BM, Schulze CJ, Yang D, Ogasawara D, Dix MM, Rogers ZN, Chuang CH, McFarland CD, Chiou SH, Brown JM, Cravatt BF, Bogyo M, Winslow MM. An in vivo multiplexed small-molecule screening platform. Nature Methods. PMID 27617390 DOI: 10.1038/nmeth.3992  0.92
2016 Abd-Elrahman I, Kosuge H, Wises Sadan T, Ben-Nun Y, Meir K, Rubinstein C, Bogyo M, McConnell MV, Blum G. Cathepsin Activity-Based Probes and Inhibitor for Preclinical Atherosclerosis Imaging and Macrophage Depletion. Plos One. 11: e0160522. PMID 27532109 DOI: 10.1371/journal.pone.0160522  0.36
2016 Edgington-Mitchell LE, Wartmann T, Fleming AK, Gocheva V, van der Linden WA, Withana NP, Verdoes M, Aurelio L, Edgington-Mitchell D, Lieu T, Parker BS, Graham B, Reinheckel T, Furness JB, Joyce JA, ... ... Bogyo M, et al. Legumain is Activated in Macrophages during Pancreatitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00047.2016. PMID 27514475 DOI: 10.1152/ajpgi.00047.2016  0.92
2016 van der Linden WA, Schulze CJ, Herbert AS, Krause TB, Wirchnianski AA, Dye JM, Chandran K, Bogyo M. Cysteine Cathepsin Inhibitors as Anti-Ebola Agents. Acs Infectious Diseases. 2: 173-179. PMID 27347558 DOI: 10.1021/acsinfecdis.5b00130  0.92
2016 Withana NP, Saito T, Ma X, Garland M, Liu C, Kosuge H, Amsallem M, Verdoes M, Ofori LO, Fischbein M, Arakawa M, Cheng Z, McConnell MV, Bogyo M. Dual Modality Activity Based Probes as Molecular Imaging Agents for Vascular Inflammation. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 27199363 DOI: 10.2967/jnumed.115.171553  0.92
2016 Sensarn S, Zavaleta CL, Segal E, Rogalla S, Lee W, Gambhir SS, Bogyo M, Contag CH. A Clinical Wide-Field Fluorescence Endoscopic Device for Molecular Imaging Demonstrating Cathepsin Protease Activity in Colon Cancer. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 27154508 DOI: 10.1007/s11307-016-0956-7  0.92
2016 Sanman LE, Qian Y, Eisele NA, Ng TM, van der Linden WA, Monack DM, Weerapana E, Bogyo M. Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death. Elife. 5. PMID 27011353 DOI: 10.7554/eLife.13663  0.92
2016 Garland M, Yim JJ, Bogyo M. A Bright Future for Precision Medicine: Advances in Fluorescent Chemical Probe Design and Their Clinical Application. Cell Chemical Biology. 23: 122-36. PMID 26933740 DOI: 10.1016/j.chembiol.2015.12.003  0.92
2016 Li H, O'Donoghue AJ, van der Linden WA, Xie SC, Yoo E, Foe IT, Tilley L, Craik CS, da Fonseca PC, Bogyo M. Structure- and function-based design of Plasmodium-selective proteasome inhibitors. Nature. 530: 233-6. PMID 26863983 DOI: 10.1038/nature16936  0.92
2016 Withana NP, Ma X, McGuire HM, Verdoes M, van der Linden WA, Ofori LO, Zhang R, Li H, Sanman LE, Wei K, Yao S, Wu P, Li F, Huang H, Xu Z, ... ... Bogyo M, et al. Non-invasive Imaging of Idiopathic Pulmonary Fibrosis Using Cathepsin Protease Probes. Scientific Reports. 6: 19755. PMID 26797565 DOI: 10.1038/srep19755  0.92
2015 Lauterwasser EM, Fontaine SD, Li H, Gut J, Katneni K, Charman SA, Rosenthal PJ, Bogyo M, Renslo AR. Trioxolane-Mediated Delivery of Mefloquine Limits Brain Exposure in a Mouse Model of Malaria. Acs Medicinal Chemistry Letters. 6: 1145-1149. PMID 26617969 DOI: 10.1021/acsmedchemlett.5b00296  0.92
2015 Foe IT, Child MA, Majmudar JD, Krishnamurthy S, van der Linden WA, Ward GE, Martin BR, Bogyo M. Global Analysis of Palmitoylated Proteins in Toxoplasma gondii. Cell Host & Microbe. 18: 501-11. PMID 26468752 DOI: 10.1016/j.chom.2015.09.006  0.92
2015 Rosenthal EL, Warram JM, de Boer E, Basilion JP, Biel MA, Bogyo M, Bouvet M, Brigman BE, Colson YL, DeMeester SR, Gurtner GC, Ishizawa T, Jacobs PM, Keereweer S, Liao JC, et al. Successful Translation of Fluorescence Navigation During Oncologic Surgery: A Consensus Report. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 26449839 DOI: 10.2967/jnumed.115.158915  0.92
2015 Bender KO, Garland M, Ferreyra JA, Hryckowian AJ, Child MA, Puri AW, Solow-Cordero DE, Higginbottom SK, Segal E, Banaei N, Shen A, Sonnenburg JL, Bogyo M. A small-molecule antivirulence agent for treating Clostridium difficile infection. Science Translational Medicine. 7: 306ra148. PMID 26400909 DOI: 10.1126/scitranslmed.aac9103  0.92
2015 Staniec D, Ksiazek M, Thøgersen IB, Enghild JJ, Sroka A, Bryzek D, Bogyo M, Abrahamson M, Potempa J. Calcium Regulates the Activity and Structural Stability of Tpr, a Bacterial Calpain-like Peptidase. The Journal of Biological Chemistry. 290: 27248-60. PMID 26385924 DOI: 10.1074/jbc.M115.648782  0.92
2015 Edgington-Mitchell LE, Rautela J, Duivenvoorden HM, Jayatilleke KM, van der Linden WA, Verdoes M, Bogyo M, Parker BS. Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer. Oncotarget. 6: 27008-22. PMID 26308073 DOI: 10.18632/oncotarget.4714  0.92
2015 Ofori LO, Withana NP, Prestwood TR, Verdoes M, Brady JJ, Winslow MM, Sorger J, Bogyo M. Design of Protease Activated Optical Contrast Agents That Exploit a Latent Lysosomotropic Effect for Use in Fluorescence-Guided Surgery. Acs Chemical Biology. 10: 1977-88. PMID 26039341 DOI: 10.1021/acschembio.5b00205  0.92
2015 Gangoda L, Keerthikumar S, Fonseka P, Edgington LE, Ang CS, Ozcitti C, Bogyo M, Parker BS, Mathivanan S. Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin. Oncotarget. 6: 11175-90. PMID 25883214  0.36
2015 Oresic Bender K, Ofori L, van der Linden WA, Mock ED, Datta GK, Chowdhury S, Li H, Segal E, Sanchez Lopez M, Ellman JA, Figdor CG, Bogyo M, Verdoes M. Design of a highly selective quenched activity-based probe and its application in dual color imaging studies of cathepsin S activity localization. Journal of the American Chemical Society. 137: 4771-7. PMID 25785540 DOI: 10.1021/jacs.5b00315  0.92
2015 Segal E, Prestwood TR, van der Linden WA, Carmi Y, Bhattacharya N, Withana N, Verdoes M, Habtezion A, Engleman EG, Bogyo M. Detection of intestinal cancer by local, topical application of a quenched fluorescence probe for cysteine cathepsins. Chemistry & Biology. 22: 148-58. PMID 25579207 DOI: 10.1016/j.chembiol.2014.11.008  0.92
2015 Hachmann J, Edgington-Mitchell LE, Poreba M, Sanman LE, Drag M, Bogyo M, Salvesen GS. Probes to monitor activity of the paracaspase MALT1. Chemistry & Biology. 22: 139-47. PMID 25556944 DOI: 10.1016/j.chembiol.2014.11.011  0.92
2014 Li H, van der Linden WA, Verdoes M, Florea BI, McAllister FE, Govindaswamy K, Elias JE, Bhanot P, Overkleeft HS, Bogyo M. Assessing subunit dependency of the Plasmodium proteasome using small molecule inhibitors and active site probes. Acs Chemical Biology. 9: 1869-76. PMID 24918547 DOI: 10.1021/cb5001263  0.92
2014 Haedke UR, Frommel SC, Hansen F, Hahne H, Kuster B, Bogyo M, Verhelst SHL. Phosphoramidates as novel activity-based probes for serine proteases Chembiochem. 15: 1106-1110. PMID 24817682 DOI: 10.1002/cbic.201400013  0.92
2014 Razorenova OV, Castellini L, Colavitti R, Edgington LE, Nicolau M, Huang X, Bedogni B, Mills EM, Bogyo M, Giaccia AJ. The apoptosis repressor with a CARD domain (ARC) gene is a direct hypoxia-inducible factor 1 target gene and promotes survival and proliferation of VHL-deficient renal cancer cells. Molecular and Cellular Biology. 34: 739-51. PMID 24344197 DOI: 10.1128/MCB.00644-12  0.92
2013 Rothberg JM, Bailey KM, Wojtkowiak JW, Ben-Nun Y, Bogyo M, Weber E, Moin K, Blum G, Mattingly RR, Gillies RJ, Sloane BF. Acid-mediated tumor proteolysis: contribution of cysteine cathepsins. Neoplasia (New York, N.Y.). 15: 1125-37. PMID 24204192 DOI: 10.1593/neo.13946  0.92
2013 Deu E, Chen IT, Lauterwasser EM, Valderramos J, Li H, Edgington LE, Renslo AR, Bogyo M. Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo. Proceedings of the National Academy of Sciences of the United States of America. 110: 18244-9. PMID 24145449 DOI: 10.1073/pnas.1312782110  0.92
2013 Verdoes M, Oresic Bender K, Segal E, Van Der Linden WA, Syed S, Withana NP, Sanman LE, Bogyo M. Improved quenched fluorescent probe for imaging of cysteine cathepsin activity Journal of the American Chemical Society. 135: 14726-14730. PMID 23971698 DOI: 10.1021/ja4056068  0.92
2013 Child MA, Hall CI, Beck JR, Ofori LO, Albrow VE, Garland M, Bowyer PW, Bradley PJ, Powers JC, Boothroyd JC, Weerapana E, Bogyo M. Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion. Nature Chemical Biology. 9: 651-6. PMID 23934245 DOI: 10.1038/nchembio.1315  0.92
2013 Tanaka TQ, Deu E, Molina-Cruz A, Ashburne MJ, Ali O, Suri A, Kortagere S, Bogyo M, Williamson KC. Plasmodium dipeptidyl aminopeptidases as malaria transmission-blocking drug targets. Antimicrobial Agents and Chemotherapy. 57: 4645-52. PMID 23836185 DOI: 10.1128/AAC.02495-12  0.92
2013 Gloeckl S, Ong VA, Patel P, Tyndall JD, Timms P, Beagley KW, Allan JA, Armitage CW, Turnbull L, Whitchurch CB, Merdanovic M, Ehrmann M, Powers JC, Oleksyszyn J, Verdoes M, ... Bogyo M, et al. Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatis. Molecular Microbiology. 89: 676-89. PMID 23796320 DOI: 10.1111/mmi.12306  0.92
2013 Edgington LE, Bogyo M. In vivo imaging and biochemical characterization of protease function using fluorescent activity-based probes. Current Protocols in Chemical Biology. 5: 25-44. PMID 23788323 DOI: 10.1002/9780470559277.ch120235  0.36
2013 Xiao J, Broz P, Puri AW, Deu E, Morell M, Monack DM, Bogyo M. A coupled protein and probe engineering approach for selective inhibition and activity-based probe labeling of the caspases. Journal of the American Chemical Society. 135: 9130-8. PMID 23701470 DOI: 10.1021/ja403521u  0.32
2013 Morell M, Nguyen Duc T, Willis AL, Syed S, Lee J, Deu E, Deng Y, Xiao J, Turk BE, Jessen JR, Weiss SJ, Bogyo M. Coupling protein engineering with probe design to inhibit and image matrix metalloproteinases with controlled specificity. Journal of the American Chemical Society. 135: 9139-48. PMID 23701445 DOI: 10.1021/ja403523p  0.92
2013 Godinat A, Park HM, Miller SC, Cheng K, Hanahan D, Sanman LE, Bogyo M, Yu A, Nikitin GF, Stahl A, Dubikovskaya EA. A biocompatible in vivo ligation reaction and its application for noninvasive bioluminescent imaging of protease activity in living mice. Acs Chemical Biology. 8: 987-99. PMID 23463944 DOI: 10.1021/cb3007314  0.92
2013 Lee J, Bogyo M. Target deconvolution techniques in modern phenotypic profiling. Current Opinion in Chemical Biology. 17: 118-26. PMID 23337810 DOI: 10.1016/j.cbpa.2012.12.022  0.92
2013 Edgington LE, Verdoes M, Ortega A, Withana NP, Lee J, Syed S, Bachmann MH, Blum G, Bogyo M. Functional imaging of legumain in cancer using a new quenched activity-based probe. Journal of the American Chemical Society. 135: 174-82. PMID 23215039 DOI: 10.1021/ja307083b  0.92
2012 Mullins SR, Sameni M, Blum G, Bogyo M, Sloane BF, Moin K. Three-dimensional cultures modeling premalignant progression of human breast epithelial cells: role of cysteine cathepsins. Biological Chemistry. 393: 1405-16. PMID 23667900 DOI: 10.1515/hsz-2012-0252  0.92
2012 Stolze SC, Deu E, Kaschani F, Li N, Florea BI, Richau KH, Colby T, van der Hoorn RA, Overkleeft HS, Bogyo M, Kaiser M. The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains. Chemistry & Biology. 19: 1546-55. PMID 23261598 DOI: 10.1016/j.chembiol.2012.09.020  0.92
2012 Li H, Ponder EL, Verdoes M, Asbjornsdottir KH, Deu E, Edgington LE, Lee JT, Kirk CJ, Demo SD, Williamson KC, Bogyo M. Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity. Chemistry & Biology. 19: 1535-45. PMID 23142757 DOI: 10.1016/j.chembiol.2012.09.019  0.92
2012 Salvesen GS, Bogyo M. Highlight: the universe of proteolytic networks and mechanisms. Biological Chemistry. 393: 841. PMID 22944685 DOI: 10.1515/hsz-2012-0262  0.92
2012 Lyo V, Cattaruzza F, Kim TN, Walker AW, Paulick M, Cox D, Cloyd J, Buxbaum J, Ostroff J, Bogyo M, Grady EF, Bunnett NW, Kirkwood KS. Active cathepsins B, L, and S in murine and human pancreatitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 303: G894-903. PMID 22899821 DOI: 10.1152/ajpgi.00073.2012  0.92
2012 Goussetis DJ, Gounaris E, Wu EJ, Vakana E, Sharma B, Bogyo M, Altman JK, Platanias LC. Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide. Blood. 120: 3555-62. PMID 22898604 DOI: 10.1182/blood-2012-01-402578  0.92
2012 Verdoes M, Edgington LE, Scheeren FA, Leyva M, Blum G, Weiskopf K, Bachmann MH, Ellman JA, Bogyo M. A nonpeptidic cathepsin S activity-based probe for noninvasive optical imaging of tumor-associated macrophages. Chemistry & Biology. 19: 619-28. PMID 22633413 DOI: 10.1016/j.chembiol.2012.03.012  0.92
2012 Edgington LE, van Raam BJ, Verdoes M, Wierschem C, Salvesen GS, Bogyo M. An optimized activity-based probe for the study of caspase-6 activation. Chemistry & Biology. 19: 340-52. PMID 22444589 DOI: 10.1016/j.chembiol.2011.12.021  0.92
2012 Cutter JL, Cohen NT, Wang J, Sloan AE, Cohen AR, Panneerselvam A, Schluchter M, Blum G, Bogyo M, Basilion JP. Topical application of activity-based probes for visualization of brain tumor tissue. Plos One. 7: e33060. PMID 22427947 DOI: 10.1371/journal.pone.0033060  0.36
2012 Richau KH, Kaschani F, Verdoes M, Pansuriya TC, Niessen S, Stüber K, Colby T, Overkleeft HS, Bogyo M, Van der Hoorn RA. Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics. Plant Physiology. 158: 1583-99. PMID 22371507 DOI: 10.1104/pp.112.194001  0.92
2012 Fritz HM, Bowyer PW, Bogyo M, Conrad PA, Boothroyd JC. Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance. Plos One. 7: e29955. PMID 22279555 DOI: 10.1371/journal.pone.0029955  0.92
2012 Withana NP, Blum G, Sameni M, Slaney C, Anbalagan A, Olive MB, Bidwell BN, Edgington L, Wang L, Moin K, Sloane BF, Anderson RL, Bogyo MS, Parker BS. Cathepsin B inhibition limits bone metastasis in breast cancer. Cancer Research. 72: 1199-209. PMID 22266111 DOI: 10.1158/0008-5472.CAN-11-2759  0.92
2012 Ferreira KS, Kreutz C, Macnelly S, Neubert K, Haber A, Bogyo M, Timmer J, Borner C. Caspase-3 feeds back on caspase-8, Bid and XIAP in type I Fas signaling in primary mouse hepatocytes. Apoptosis : An International Journal On Programmed Cell Death. 17: 503-15. PMID 22246639 DOI: 10.1007/s10495-011-0691-0  0.92
2012 Lee J, Bogyo M. Synthesis and evaluation of aza-peptidyl inhibitors of the lysosomal asparaginyl endopeptidase, legumain. Bioorganic & Medicinal Chemistry Letters. 22: 1340-3. PMID 22243962 DOI: 10.1016/j.bmcl.2011.12.079  0.92
2012 Deu E, Verdoes M, Bogyo M. New approaches for dissecting protease functions to improve probe development and drug discovery. Nature Structural & Molecular Biology. 19: 9-16. PMID 22218294 DOI: 10.1038/nsmb.2203  0.32
2012 Li J, Hsu HC, Yang P, Wu Q, Li H, Edgington LE, Bogyo M, Kimberly RP, Mountz JD. Treatment of arthritis by macrophage depletion and immunomodulation: testing an apoptosis-mediated therapy in a humanized death receptor mouse model. Arthritis and Rheumatism. 64: 1098-109. PMID 22006294 DOI: 10.1002/art.33423  0.92
2012 Kalińska M, Kantyka T, Greenbaum DC, Larsen KS, Władyka B, Jabaiah A, Bogyo M, Daugherty PS, Wysocka M, Jaros M, Lesner A, Rolka K, Schaschke N, Stennicke H, Dubin A, et al. Substrate specificity of Staphylococcus aureus cysteine proteases--Staphopains A, B and C. Biochimie. 94: 318-27. PMID 21802486 DOI: 10.1016/j.biochi.2011.07.020  0.92
2011 Ren G, Blum G, Verdoes M, Liu H, Syed S, Edgington LE, Gheysens O, Miao Z, Jiang H, Gambhir SS, Bogyo M, Cheng Z. Non-invasive imaging of cysteine cathepsin activity in solid tumors using a 64Cu-labeled activity-based probe. Plos One. 6: e28029. PMID 22132198 DOI: 10.1371/journal.pone.0028029  0.36
2011 Edgington LE, Verdoes M, Bogyo M. Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes. Current Opinion in Chemical Biology. 15: 798-805. PMID 22098719 DOI: 10.1016/j.cbpa.2011.10.012  0.36
2011 Tedelind S, Jordans S, Resemann H, Blum G, Bogyo M, Führer D, Brix K. Cathepsin B trafficking in thyroid carcinoma cells. Thyroid Research. 4: S2. PMID 21835049 DOI: 10.1186/1756-6614-4-S1-S2  0.36
2011 Cattaruzza F, Lyo V, Jones E, Pham D, Hawkins J, Kirkwood K, Valdez-Morales E, Ibeakanma C, Vanner SJ, Bogyo M, Bunnett NW. Cathepsin S is activated during colitis and causes visceral hyperalgesia by a PAR2-dependent mechanism in mice. Gastroenterology. 141: 1864-74.e1-3. PMID 21802389 DOI: 10.1053/j.gastro.2011.07.035  0.92
2011 Albrow VE, Ponder EL, Fasci D, Békés M, Deu E, Salvesen GS, Bogyo M. Development of small molecule inhibitors and probes of human SUMO deconjugating proteases. Chemistry & Biology. 18: 722-32. PMID 21700208 DOI: 10.1016/j.chembiol.2011.05.008  0.92
2011 Ponder EL, Albrow VE, Leader BA, Békés M, Mikolajczyk J, Fonović UP, Shen A, Drag M, Xiao J, Deu E, Campbell AJ, Powers JC, Salvesen GS, Bogyo M. Functional characterization of a SUMO deconjugating protease of Plasmodium falciparum using newly identified small molecule inhibitors. Chemistry & Biology. 18: 711-21. PMID 21700207 DOI: 10.1016/j.chembiol.2011.04.010  0.92
2011 Hall CI, Reese ML, Weerapana E, Child MA, Bowyer PW, Albrow VE, Haraldsen JD, Phillips MR, Sandoval ED, Ward GE, Cravatt BF, Boothroyd JC, Bogyo M. Chemical genetic screen identifies Toxoplasma DJ-1 as a regulator of parasite secretion, attachment, and invasion. Proceedings of the National Academy of Sciences of the United States of America. 108: 10568-73. PMID 21670272 DOI: 10.1073/pnas.1105622108  0.92
2011 Boutté AM, Friedman DB, Bogyo M, Min Y, Yang L, Lin PC. Identification of a myeloid-derived suppressor cell cystatin-like protein that inhibits metastasis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2626-37. PMID 21518852 DOI: 10.1096/fj.10-180604  0.92
2011 Ewald SE, Engel A, Lee J, Wang M, Bogyo M, Barton GM. Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase. The Journal of Experimental Medicine. 208: 643-51. PMID 21402738 DOI: 10.1084/jem.20100682  0.92
2011 Mahajan SS, Deu E, Lauterwasser EM, Leyva MJ, Ellman JA, Bogyo M, Renslo AR. A fragmenting hybrid approach for targeted delivery of multiple therapeutic agents to the malaria parasite. Chemmedchem. 6: 415-9. PMID 21360816 DOI: 10.1002/cmdc.201100002  0.92
2011 Paulick MG, Bogyo M. Development of activity-based probes for cathepsin X. Acs Chemical Biology. 6: 563-72. PMID 21322635 DOI: 10.1021/cb100392r  0.36
2011 Shen A, Lupardus PJ, Gersch MM, Puri AW, Albrow VE, Garcia KC, Bogyo M. Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins. Nature Structural & Molecular Biology. 18: 364-71. PMID 21317893 DOI: 10.1038/nsmb.1990  0.92
2011 Bowyer PW, Simon GM, Cravatt BF, Bogyo M. Global profiling of proteolysis during rupture of Plasmodium falciparum from the host erythrocyte. Molecular & Cellular Proteomics : McP. 10: M110.001636. PMID 20943600 DOI: 10.1074/mcp.M110.001636  0.92
2011 Wang F, Krai P, Deu E, Bibb B, Lauritzen C, Pedersen J, Bogyo M, Klemba M. Biochemical characterization of Plasmodium falciparum dipeptidyl aminopeptidase 1. Molecular and Biochemical Parasitology. 175: 10-20. PMID 20833209 DOI: 10.1016/j.molbiopara.2010.08.004  0.32
2010 Puri AW, Lupardus PJ, Deu E, Albrow VE, Garcia KC, Bogyo M, Shen A. Rational design of inhibitors and activity-based probes targeting Clostridium difficile virulence factor TcdB. Chemistry & Biology. 17: 1201-11. PMID 21095570 DOI: 10.1016/j.chembiol.2010.09.011  0.92
2010 Deu E, Leyva MJ, Albrow VE, Rice MJ, Ellman JA, Bogyo M. Functional studies of Plasmodium falciparum dipeptidyl aminopeptidase I using small molecule inhibitors and active site probes. Chemistry & Biology. 17: 808-19. PMID 20797610 DOI: 10.1016/j.chembiol.2010.06.007  0.92
2010 Deu E, Yang Z, Wang F, Klemba M, Bogyo M. Use of activity-based probes to develop high throughput screening assays that can be performed in complex cell extracts. Plos One. 5: e11985. PMID 20700487 DOI: 10.1371/journal.pone.0011985  0.32
2010 Lee J, Bogyo M. Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain. Acs Chemical Biology. 5: 233-43. PMID 20017516 DOI: 10.1021/cb900232a  0.92
2010 Drag M, Bogyo M, Ellman JA, Salvesen GS. Aminopeptidase fingerprints, an integrated approach for identification of good substrates and optimal inhibitors. The Journal of Biological Chemistry. 285: 3310-8. PMID 19948737 DOI: 10.1074/jbc.M109.060418  0.92
2009 Ravindran S, Lodoen MB, Verhelst SH, Bogyo M, Boothroyd JC. 4-Bromophenacyl bromide specifically inhibits rhoptry secretion during Toxoplasma invasion. Plos One. 4: e8143. PMID 19956582 DOI: 10.1371/journal.pone.0008143  0.92
2009 Shen A, Lupardus PJ, Morell M, Ponder EL, Sadaghiani AM, Garcia KC, Bogyo M. Simplified, enhanced protein purification using an inducible, autoprocessing enzyme tag. Plos One. 4: e8119. PMID 19956581 DOI: 10.1371/journal.pone.0008119  0.92
2009 Zhang J, Fonovic M, Suyama K, Bogyo M, Scott MP. Rab35 controls actin bundling by recruiting fascin as an effector protein. Science (New York, N.Y.). 325: 1250-4. PMID 19729655 DOI: 10.1126/science.1174921  0.92
2009 Blum G, Weimer RM, Edgington LE, Adams W, Bogyo M. Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity. Plos One. 4: e6374. PMID 19636372 DOI: 10.1371/journal.pone.0006374  0.92
2009 Edgington LE, Berger AB, Blum G, Albrow VE, Paulick MG, Lineberry N, Bogyo M. Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes. Nature Medicine. 15: 967-73. PMID 19597506 DOI: 10.1038/nm.1938  0.92
2009 Larson ET, Parussini F, Huynh MH, Giebel JD, Kelley AM, Zhang L, Bogyo M, Merritt EA, Carruthers VB. Toxoplasma gondii cathepsin L is the primary target of the invasion-inhibitory compound morpholinurea-leucyl-homophenyl-vinyl sulfone phenyl. The Journal of Biological Chemistry. 284: 26839-50. PMID 19596863 DOI: 10.1074/jbc.M109.003780  0.92
2009 Shen A, Lupardus PJ, Albrow VE, Guzzetta A, Powers JC, Garcia KC, Bogyo M. Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin. Nature Chemical Biology. 5: 469-78. PMID 19465933 DOI: 10.1038/nchembio.178  0.92
2009 Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF. VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Cancer Research. 69: 4537-44. PMID 19435903 DOI: 10.1158/0008-5472.CAN-08-4539  0.92
2009 Beckham SA, Piedrafita D, Phillips CI, Samarawickrema N, Law RH, Smooker PM, Quinsey NS, Irving JA, Greenwood D, Verhelst SH, Bogyo M, Turk B, Coetzer TH, Wijeyewickrema LC, Spithill TW, et al. A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites. The International Journal of Biochemistry & Cell Biology. 41: 1601-12. PMID 19401154 DOI: 10.1016/j.biocel.2009.02.003  0.92
2009 Barbero S, Mielgo A, Torres V, Teitz T, Shields DJ, Mikolon D, Bogyo M, Barilà D, Lahti JM, Schlaepfer D, Stupack DG. Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis. Cancer Research. 69: 3755-63. PMID 19383910 DOI: 10.1158/0008-5472.CAN-08-3937  0.92
2009 Cavallo-Medved D, Rudy D, Blum G, Bogyo M, Caglic D, Sloane BF. Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation. Experimental Cell Research. 315: 1234-46. PMID 19331819 DOI: 10.1016/j.yexcr.2009.01.021  0.92
2009 Liz MA, Fleming CE, Nunes AF, Almeida MR, Mar FM, Choe Y, Craik CS, Powers JC, Bogyo M, Sousa MM. Substrate specificity of transthyretin: identification of natural substrates in the nervous system. The Biochemical Journal. 419: 467-74. PMID 19138167 DOI: 10.1042/BJ20082090  0.92
2008 Arastu-Kapur S, Ponder EL, Fonović UP, Yeoh S, Yuan F, Fonović M, Grainger M, Phillips CI, Powers JC, Bogyo M. Identification of proteases that regulate erythrocyte rupture by the malaria parasite Plasmodium falciparum. Nature Chemical Biology. 4: 203-13. PMID 18246061 DOI: 10.1038/nchembio.70  0.92
2007 Ponder EL, Bogyo M. Ubiquitin-like modifiers and their deconjugating enzymes in medically important parasitic protozoa. Eukaryotic Cell. 6: 1943-52. PMID 17905920 DOI: 10.1128/EC.00282-07  0.92
2007 Sexton KB, Kato D, Berger AB, Fonovic M, Verhelst SHL, Bogyo M. Specificity of aza-peptide electrophile activity-based probes of caspases Cell Death and Differentiation. 14: 727-732. PMID 17170749 DOI: 10.1038/sj.cdd.4402074  0.92
2006 Berger AB, Sexton KB, Bogyo M. Commonly used caspase inhibitors designed based on substrate specificity profiles lack selectivity Cell Research. 16: 961-963. PMID 17117159 DOI: 10.1038/sj.cr.7310112  0.92
2006 Berger AB, Witte MD, Denault JB, Sadaghiani AM, Sexton KM, Salvesen GS, Bogyo M. Identification of early intermediates of caspase activation using selective inhibitors and activity-based probes. Molecular Cell. 23: 509-21. PMID 16916639 DOI: 10.1016/j.molcel.2006.06.021  0.92
2005 Kato D, Boatright KM, Berger AB, Nazif T, Blum G, Ryan C, Chehade KA, Salvesen GS, Bogyo M. Activity-based probes that target diverse cysteine protease families. Nature Chemical Biology. 1: 33-8. PMID 16407991 DOI: 10.1038/nchembio707  0.92
2004 Berger AB, Vitorino PM, Bogyo M. Activity-based protein profiling: applications to biomarker discovery, in vivo imaging and drug discovery. American Journal of Pharmacogenomics : Genomics-Related Research in Drug Development and Clinical Practice. 4: 371-81. PMID 15651898  1
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