Herny W. Strobel - Publications

The University of Texas Graduate School of Biomedical Sciences at Houston 
Biochemistry, Molecular Biology

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Ravindranath V, Strobel HW. Cytochrome P450-mediated metabolism in brain: Functional roles and their implications Expert Opinion On Drug Metabolism and Toxicology. 9: 551-558. PMID 23330950 DOI: 10.1517/17425255.2013.759208  0.56
2008 Agarwal V, Kommaddi RP, Valli K, Ryder D, Hyde TM, Kleinman JE, Strobel HW, Ravindranath V. Drug metabolism in human brain: high levels of cytochrome P4503A43 in brain and metabolism of anti-anxiety drug alprazolam to its active metabolite. Plos One. 3: e2337. PMID 18545703 DOI: 10.1371/Journal.Pone.0002337  0.619
2008 Kalsotra A, Du L, Wang Y, Ladd PA, Kikuta Y, Duvic M, Boyd AS, Keeney DS, Strobel HW. Inflammation resolved by retinoid X receptor-mediated inactivation of leukotriene signaling pathways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 538-47. PMID 17884973 DOI: 10.1096/Fj.07-9244Com  0.357
2007 Williams ET, Schouest KR, Leyk M, Strobel HW. The chimpanzee cytochrome P450 3A subfamily: Is our closest related species really that similar? Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics. 2: 91-100. PMID 20483282 DOI: 10.1016/J.Cbd.2006.12.004  0.416
2007 Kommaddi RP, Turman CM, Moorthy B, Wang L, Strobel HW, Ravindranath V. An alternatively spliced cytochrome P4501A1 in human brain fails to bioactivate polycyclic aromatic hydrocarbons to DNA-reactive metabolites. Journal of Neurochemistry. 102: 867-77. PMID 17630984 DOI: 10.1111/J.1471-4159.2007.04599.X  0.423
2007 Anakk S, Huang W, Staudinger JL, Tan K, Cole TJ, Moore DD, Strobel HW. Gender dictates the nuclear receptor-mediated regulation of CYP3A44. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 36-42. PMID 17020958 DOI: 10.1124/Dmd.106.011270  0.341
2006 Kalsotra A, Strobel HW. Cytochrome P450 4F subfamily: at the crossroads of eicosanoid and drug metabolism. Pharmacology & Therapeutics. 112: 589-611. PMID 16926051 DOI: 10.1016/J.Pharmthera.2006.03.008  0.562
2005 Chinta SJ, Kommaddi RP, Turman CM, Strobel HW, Ravindranath V. Constitutive expression and localization of cytochrome P-450 1A1 in rat and human brain: presence of a splice variant form in human brain. Journal of Neurochemistry. 93: 724-36. PMID 15836631 DOI: 10.1111/J.1471-4159.2005.03061.X  0.494
2004 Kalsotra A, Turman CM, Kikuta Y, Strobel HW. Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids. Toxicology and Applied Pharmacology. 199: 295-304. PMID 15364545 DOI: 10.1016/J.Taap.2003.12.033  0.433
2004 Williams ET, Leyk M, Wrighton SA, Davies PJ, Loose DS, Shipley GL, Strobel HW. Estrogen regulation of the cytochrome P450 3A subfamily in humans. The Journal of Pharmacology and Experimental Therapeutics. 311: 728-35. PMID 15282264 DOI: 10.1124/Jpet.104.068908  0.383
2004 Anakk S, Kalsotra A, Kikuta Y, Huang W, Zhang J, Staudinger JL, Moore DD, Strobel HW. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11. The Pharmacogenomics Journal. 4: 91-101. PMID 14770174 DOI: 10.1038/Sj.Tpj.6500222  0.358
2003 Kalsotra A, Turman CM, Dash PK, Strobel HW. Differential effects of traumatic brain injury on the cytochrome p450 system: a perspective into hepatic and renal drug metabolism. Journal of Neurotrauma. 20: 1339-50. PMID 14748982 DOI: 10.1089/089771503322686139  0.574
2003 Anakk S, Kalsotra A, Shen Q, Vu MT, Staudinger JL, Davies PJA, Strobel HW. Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1736-1738. PMID 12958193 DOI: 10.1096/Fj.02-1004Fje  0.407
2003 Anakk S, Ku CY, Vore M, Strobel HW. Insights into gender bias: rat cytochrome P450 3A9. The Journal of Pharmacology and Experimental Therapeutics. 305: 703-9. PMID 12606633 DOI: 10.1124/Jpet.102.048090  0.376
2002 Cui X, Strobel HW. Cloning and characterization of the rat cytochrome P450 4F5 (CYP4F5) gene. Gene. 297: 179-87. PMID 12384299 DOI: 10.1016/S0378-1119(02)00885-5  0.324
2002 Kalsotra A, Anakk S, Boehme CL, Strobel HW. Sexual dimorphism and tissue specificity in the expression of CYP4F forms in Sprague Dawley rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 30: 1022-8. PMID 12167568 DOI: 10.1124/Dmd.30.9.1022  0.364
2001 Strobel HW, Thompson CM, Antonovic L. Cytochromes P450 in brain: function and significance. Current Drug Metabolism. 2: 199-214. PMID 11469726 DOI: 10.2174/1389200013338577  0.482
2000 Thompson CM, Capdevila JH, Strobel HW. Recombinant cytochrome P450 2D18 metabolism of dopamine and arachidonic acid. The Journal of Pharmacology and Experimental Therapeutics. 294: 1120-30. PMID 10945868  0.306
2000 Voirol P, Jonzier-Perey M, Porchet F, Reymond MJ, Janzer RC, Bouras C, Strobel HW, Kosel M, Eap CB, Baumann P. Cytochrome P-450 activities in human and rat brain microsomes. Brain Research. 855: 235-43. PMID 10677595 DOI: 10.1016/S0006-8993(99)02354-9  0.448
1999 Kapitulnik J, Strobel HW. Extrahepatic drug metabolizing enzymes. Journal of Biochemical and Molecular Toxicology. 13: 227-30. PMID 10402555 DOI: 10.1002/(Sici)1099-0461(1999)13:5<227::Aid-Jbt1>3.0.Co;2-1  0.629
1998 Thompson CM, Kawashima H, Strobel HW. Isolation of partially purified P450 2D18 and characterization of activity toward the tricyclic antidepressants imipramine and desipramine. Archives of Biochemistry and Biophysics. 359: 115-21. PMID 9799568 DOI: 10.1006/Abbi.1998.0892  0.336
1998 Geng J, Strobel HW. Expression, induction and regulation of the cytochrome P450 monooxygenase system in the rat glioma C6 cell line. Brain Research. 784: 276-83. PMID 9518647 DOI: 10.1016/S0006-8993(97)01346-2  0.315
1997 Geng J, Strobel HW. Expression and induction of cytochrome P-450 1A1 and P-450 2D subfamily in the rat glioma C6 cell line. Brain Research. 774: 11-9. PMID 9452186 DOI: 10.1016/S0006-8993(97)81681-2  0.335
1997 Strobel HW, Geng J, Kawashima H, Wang H. Cytochrome P450-dependent biotransformation of drugs and other xenobiotic substrates in neural tissue. Drug Metabolism Reviews. 29: 1079-105. PMID 9421686 DOI: 10.3109/03602539709002244  0.55
1997 Baum LO, Strobel HW. Regulation of expression of cytochrome P-450 2D mRNA in rat brain with steroid hormones. Brain Research. 765: 67-73. PMID 9310395 DOI: 10.1016/S0006-8993(97)00428-9  0.305
1997 Wang H, Strobel HW. Regulation of CYP3A9 gene expression by estrogen and catalytic studies using cytochrome P450 3A9 expressed in Escherichia coli. Archives of Biochemistry and Biophysics. 344: 365-72. PMID 9264551 DOI: 10.1006/Abbi.1997.0230  0.346
1996 Sequeira DJ, Strobel HW. In vitro metabolism of imipramine by brain microsomes: effects of inhibitors and exogenous cytochrome P450 reductase. Brain Research. 738: 24-31. PMID 8949923 DOI: 10.1016/0006-8993(96)00759-7  0.398
1996 Kawashima H, Sequeira DJ, Nelson DR, Strobel HW. Genomic cloning and protein expression of a novel rat brain cytochrome P-450 CYP2D18* catalyzing imipramine N-demethylation. The Journal of Biological Chemistry. 271: 28176-80. PMID 8910433 DOI: 10.1074/Jbc.271.45.28176  0.356
1996 Ahmed SS, Napoli KL, Strobel HW. Oxygen radical formation due to the effect of varying hydrogen ion concentrations on cytochrome P450-catalyzed cyclosporine metabolism in rat and human liver microsomes. Advances in Experimental Medicine and Biology. 387: 135-9. PMID 8794205  0.306
1995 Sequeira DJ, Strobel HW. High-performance liquid chromatographic method for the analysis of imipramine metabolism in vitro by liver and brain microsomes. Journal of Chromatography. B, Biomedical Applications. 673: 251-8. PMID 8611959 DOI: 10.1016/0378-4347(95)00274-X  0.362
1995 Strobel HW, Kawashima H, Geng J, Sequeira D, Bergh A, Hodgson AV, Wang H, Shen S. Expression of multiple forms of brain cytochrome P450. Toxicology Letters. 82: 639-43. PMID 8597121 DOI: 10.1016/0378-4274(95)03509-5  0.479
1993 Hodgson AV, White TB, White JW, Strobel HW. Expression analysis of the mixed function oxidase system in rat brain by the polymerase chain reaction. Molecular and Cellular Biochemistry. 120: 171-9. PMID 8487757 DOI: 10.1007/Bf00926090  0.509
1993 Serino F, Grevel J, Napoli KL, Kahan BD, Strobel HW. Generation of oxygen free radicals during the metabolism of cyclosporine A: a cause-effect relationship with metabolism inhibition. Molecular and Cellular Biochemistry. 122: 101-12. PMID 8232241 DOI: 10.1007/Bf01076094  0.314
1993 Geng J, Strobel HW. Identification of cytochromes P450 1A2, 2A1, 2C7, 2E1 in rat glioma C6 cell line by RT-PCR and specific restriction enzyme digestion. Biochemical and Biophysical Research Communications. 197: 1179-84. PMID 7506539 DOI: 10.1006/Bbrc.1993.2601  0.334
1992 Bergh AF, Strobel HW. Reconstitution of the brain mixed function oxidase system: purification of NADPH-cytochrome P450 reductase and partial purification of cytochrome P450 from whole rat brain. Journal of Neurochemistry. 59: 575-81. PMID 1629729 DOI: 10.1111/J.1471-4159.1992.Tb09408.X  0.453
1991 Stralka D, Strobel HW. Characterization of cytochrome P450-dependent dimethylhydrazine metabolism in human colon microsomes. Cancer. 68: 2363-9. PMID 1933772 DOI: 10.1002/1097-0142(19911201)68:11<2363::Aid-Cncr2820681106>3.0.Co;2-O  0.412
1991 Strobel HW, Hammond DK, White TB, white JW. Identification and localization of cytochromes P450 in gut. Methods in Enzymology. 206: 648-55. PMID 1784249 DOI: 10.1016/0076-6879(91)06135-P  0.437
1991 Hammond DK, Bjercke RJ, Langone JJ, Strobel HW. Metabolism of nicotine by rat liver cytochromes P-450. Assessment utilizing monoclonal antibodies to nicotine and cotinine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 19: 804-8. PMID 1680658  0.329
1990 Hammond DK, Strobel HW. Human colon tumor cell line LS174T drug metabolizing system. Molecular and Cellular Biochemistry. 93: 95-105. PMID 2345545 DOI: 10.1007/Bf00226181  0.326
1989 Strobel HW, Cattaneo E, Adesnik M, Maggi A. Brain cytochromes P-450 are responsive to phenobarbital and tricyclic amines. Pharmacological Research. 21: 169-75. PMID 2473464 DOI: 10.1016/1043-6618(89)90235-1  0.336
1987 Nelson DR, Strobel HW. Evolution of cytochrome P-450 proteins Molecular Biology and Evolution. 4: 572-593. PMID 3484338 DOI: 10.1093/Oxfordjournals.Molbev.A040471  0.477
1987 Oshinsky RJ, Strobel HW. Drug metabolism in rat colon: Resolution of enzymatic constituents and characterization of activity Molecular and Cellular Biochemistry. 75: 51-60. PMID 3114616 DOI: 10.1007/Bf00231608  0.386
1986 Strobel HW, Fang WF, Takazawa RS, Stralka DJ, Newaz SN, Kurzban GP, Nelson DR, Beyer RS. Cytochromes P-450 and the activation and inactivation of mutagens and carcinogens Basic Life Sciences. 39: 61-71. PMID 3094496 DOI: 10.1007/978-1-4684-5182-5_5  0.549
1982 Fennell PM, Strobel HW. Preparation of homogeneous NADPH-cytochrome P-450 reductase from rat hepatoma Biochimica Et Biophysica Acta (Bba)/Protein Structure and Molecular. 709: 173-177. PMID 6817799 DOI: 10.1016/0167-4838(82)90458-7  0.308
1980 Strobel HW, Fang WF, Oshinsky RJ. Role of colonic cytochrome P-450 in large bowel carcinogenesis Cancer. 45: 1060-1065. PMID 6766798 DOI: 10.1002/1097-0142(19800315)45:5+<1060::Aid-Cncr2820451305>3.0.Co;2-E  0.348
1979 Gum JR, Strobel HW. Purified NADPH cytochrome P-450 reductase. Interaction with hepatic microsomes and phospholipid vesicles. Journal of Biological Chemistry. 254: 4177-4185. DOI: 10.1016/s0021-9258(18)50712-2  0.316
1978 Strobel HW, Dignam JD, Saine SE, Fang WF, Fennell PM. The drug metabolism systems of liver and liver tumors: A comparison of activities and characteristics Molecular and Cellular Biochemistry. 22: 79-92. PMID 745599 DOI: 10.1007/Bf00496236  0.432
1978 Saine SE, Fang WF, Strobel HW. Drug metabolism in the novikoff hepatoma. Evidence for a mixed function oxidase system and partial purification of cytochrome P-450 reductase Bba - Enzymology. 526: 345-358. PMID 718941 DOI: 10.1016/0005-2744(78)90126-2  0.411
1978 Fang WF, Strobel HW. The drug and carcinogen metabolism system of rat colon microsomes Archives of Biochemistry and Biophysics. 186: 128-138. PMID 629529 DOI: 10.1016/0003-9861(78)90472-1  0.464
1978 Strobel HW, Dignam JD. [7] Purification and properties of NADPH-Cytochrome P-450 reductase Methods in Enzymology. 52: 89-96. PMID 209290 DOI: 10.1016/S0076-6879(78)52009-0  0.401
1977 Dignam JD, Strobel HW. NADPH-cytochrome P-450 reductase from rat liver: Purification by affinity chromatography and characterization Biochemistry. 16: 1116-1123. PMID 14671 DOI: 10.1021/Bi00625A014  0.341
1975 Dignam JD, Strobel HW. Preparation of homogeneous NADPH-cytochrome P-450 reductase from rat liver Biochemical and Biophysical Research Communications. 63: 845-852. PMID 236757 DOI: 10.1016/0006-291X(75)90644-0  0.349
1973 Coon MJ, Van Der Hoeven TA, Kaschnitz RM, Strobel HW. Biochemical studies on cytochrome P 450 solubilized from liver microsomes: partial purification and mechanism of catalysis Annals of the New York Academy of Sciences. 449-457. PMID 4155931 DOI: 10.1111/J.1749-6632.1973.Tb47613.X  0.321
1971 Coon MJ, Strobel HW, Autor AP, Heidema J, Duppel W. Functional components of the liver microsomal enzyme system catalysing fatty acid, hydrocarbon and drug hydroxylation Biochemical Journal. 125. PMID 5144730 DOI: 10.1042/Bj1250002P  0.418
1971 Coon MJ, Autor AP, Strobel HW. Role of phospholipid in electron transfer in a reconstituted liver microsomal enzyme system containing cytochrome P-450 Chemico-Biological Interactions. 3: 248-250. PMID 4399899 DOI: 10.1016/0009-2797(71)90046-9  0.45
1971 Strobel HW, Coon MJ. Effect of Superoxide Generation and Dismutation on Hydroxylation Reactions Catalyzed by Liver Microsomal Cytochrome P-450 Journal of Biological Chemistry. 246: 7826-7829. DOI: 10.1016/s0021-9258(19)45853-5  0.301
1970 Strobel HW, Lu AY, Heidema J, Coon MJ. Phosphatidylcholine Requirement in the Enzymatic Reduction of Hemoprotein P-450 and in Fatty Acid, Hydrocarbon, and Drug Hydroxylation Journal of Biological Chemistry. 245: 4851-4854. DOI: 10.1016/s0021-9258(18)62872-8  0.376
1969 Lu AY, Strobel HW, Coon MJ. Hydroxylation of benzphetamine and other drugs by a solubilized form of cytochrome P-450 from liver microsomes: lipid requirement for drug demethylation. Biochemical and Biophysical Research Communications. 36: 545-51. PMID 4390187 DOI: 10.1016/0006-291X(69)90339-8  0.494
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