Liang Tong - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
Structural Molecular Biology
Website:
http://www.columbia.edu/cu/biology/faculty-data/liang-tong/faculty.html

146 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Luo S, Xu K, Xiang S, Chen J, Chen C, Guo C, Tong Y, Tong L. High-resolution structures of inhibitor complexes of human indoleamine 2,3-dioxygenase 1 in a new crystal form. Acta Crystallographica. Section F, Structural Biology Communications. 74: 717-724. PMID 30387777 DOI: 10.1107/S2053230X18012955  0.44
2018 Wei J, Tong L. How Does Polymerization Regulate Human Acetyl-CoA Carboxylase 1? Biochemistry. PMID 30211541 DOI: 10.1021/acs.biochem.8b00881  0.4
2018 Yun JS, Yoon JH, Choi YJ, Son YJ, Kim S, Tong L, Chang JH. Molecular mechanism for the inhibition of DXO by adenosine 3',5'-bisphosphate. Biochemical and Biophysical Research Communications. PMID 30180947 DOI: 10.1016/j.bbrc.2018.08.135  0.48
2018 Dieck CL, Tzoneva G, Forouhar F, Carpenter Z, Ambesi-Impiombato A, Sánchez-Martín M, Kirschner-Schwabe R, Lew S, Seetharaman J, Tong L, Ferrando AA. Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia. Cancer Cell. 34: 136-147.e6. PMID 29990496 DOI: 10.1016/j.ccell.2018.06.003  0.72
2018 Taylor SK, Tran TH, Liu MZ, Harris PE, Sun Y, Jambawalikar SR, Tong L, Stojanovic MN. Insulin Hexamer-caged Gadolinium Ion as MRI Contrast-o-phore. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29873848 DOI: 10.1002/chem.201801388  0.32
2018 Yang H, Liao D, Tong L, Wu L, Wu K. MiR-373 exacerbates renal injury and fibrosis via NF-κB/MatrixMetalloproteinase-9 signaling by targeting Sirtuin1. Genomics. PMID 29723660 DOI: 10.1016/j.ygeno.2018.04.017  0.4
2018 Tong L, Sun X, Zhou Y. Simultaneous estimation of QTL parameters for mapping multiple traits. Journal of Genetics. 97: 267-274. PMID 29666345  0.32
2018 Luo S, Tong L. Structural biology of the separase-securin complex with crucial roles in chromosome segregation. Current Opinion in Structural Biology. 49: 114-122. PMID 29452922 DOI: 10.1016/j.sbi.2018.01.012  0.44
2017 Moremen KW, Ramiah A, Stuart M, Steel J, Meng L, Forouhar F, Moniz HA, Gahlay G, Gao Z, Chapla D, Wang S, Yang JY, Prabhakar PK, Johnson R, Rosa MD, ... ... Tong L, et al. Expression system for structural and functional studies of human glycosylation enzymes. Nature Chemical Biology. PMID 29251719 DOI: 10.1038/nchembio.2539  0.72
2017 Rogawski RT, Sergeyev IV, Zhang Y, Tran TH, Li Y, Tong L, McDermott AE. NMR Signal Quenching from Bound Biradical Affinity Reagents in DNP Samples. The Journal of Physical Chemistry. B. PMID 29116793 DOI: 10.1021/acs.jpcb.7b08274  0.48
2017 Aik WS, Lin MH, Tan D, Tripathy A, Marzluff WF, Dominski Z, Chou CY, Tong L. The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing. Plos One. 12: e0186034. PMID 29020104 DOI: 10.1371/journal.pone.0186034  0.52
2017 Zhou Y, Tong L, Chu X, Deng F, Tang J, Tang Y, Dai Y. The Adenosine A1 Receptor Antagonist DPCPX Inhibits Tumor Progression via the ERK/JNK Pathway in Renal Cell Carcinoma. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 43: 733-742. PMID 28950257 DOI: 10.1159/000481557  0.32
2017 Choi PH, Vu TMN, Pham HT, Woodward JJ, Turner MS, Tong L. Structural and functional studies of pyruvate carboxylase regulation by cyclic di-AMP in lactic acid bacteria. Proceedings of the National Academy of Sciences of the United States of America. PMID 28808024 DOI: 10.1073/pnas.1704756114  0.48
2017 Maderbocus R, Fields BL, Hamilton K, Luo S, Tran TH, Dietrich LEP, Tong L. Crystal structure of a Pseudomonas malonate decarboxylase holoenzyme hetero-tetramer. Nature Communications. 8: 160. PMID 28757619 DOI: 10.1038/s41467-017-00233-z  0.44
2017 Luo S, Tong L. Corrigendum: Molecular mechanism for the regulation of yeast separase by securin. Nature. PMID 28700574 DOI: 10.1038/nature23319  0.44
2017 Xia P, Liu J, Wang S, Ye B, Du Y, Xiong Z, Han ZG, Tong L, Fan Z. WASH maintains NKp46(+) ILC3 cells by promoting AHR expression. Nature Communications. 8: 15685. PMID 28589939 DOI: 10.1038/ncomms15685  0.32
2017 Zhou Y, Chu X, Deng F, Tong L, Tong G, Yi Y, Liu J, Tang J, Tang Y, Xia Y, Dai Y. The adenosine A2b receptor promotes tumor progression of bladder urothelial carcinoma by enhancing MAPK signaling pathway. Oncotarget. PMID 28548944 DOI: 10.18632/oncotarget.17835  0.32
2017 McFarland AP, Luo S, Ahmed-Qadri F, Zuck M, Thayer EF, Goo YA, Hybiske K, Tong L, Woodward JJ. Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State. Immunity. 46: 433-445. PMID 28329705 DOI: 10.1016/j.immuni.2017.02.014  0.44
2017 Zhou Y, Chu X, Yi Y, Tong L, Dai Y. Malignant solitary fibrous tumor in retroperitoneum: A case report and literature review. Medicine. 96: e6373. PMID 28296778 DOI: 10.1097/MD.0000000000006373  0.32
2017 Jiao X, Doamekpor SK, Bird JG, Nickels BE, Tong L, Hart RP, Kiledjian M. 5' End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding. Cell. 168: 1015-1027.e10. PMID 28283058 DOI: 10.1016/j.cell.2017.02.019  0.48
2017 Zhang Y, Shan CM, Wang J, Bao K, Tong L, Jia S. Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation. Scientific Reports. 7: 43906. PMID 28256625 DOI: 10.1038/srep43906  0.48
2017 Welsch ME, Kaplan A, Chambers JM, Stokes ME, Bos PH, Zask A, Zhang Y, Sanchez-Martin M, Badgley MA, Huang CS, Tran TH, Akkiraju H, Brown LM, Nandakumar R, Cremers S, ... ... Tong L, et al. Multivalent Small-Molecule Pan-RAS Inhibitors. Cell. 168: 878-889.e29. PMID 28235199 DOI: 10.1016/j.cell.2017.02.006  0.48
2017 Luo S, Tong L. Molecular mechanism for the regulation of yeast separase by securin. Nature. PMID 28146474 DOI: 10.1038/nature21061  0.44
2017 Zhu Y, Luo S, Sabo Y, Wang C, Tong L, Goff SP. Heme Oxygenase 2 Binds Myristate to Regulate Retrovirus Assembly and TLR4 Signaling. Cell Host & Microbe. PMID 28132836 DOI: 10.1016/j.chom.2017.01.002  0.44
2017 Li M, Zhang WK, Benvin NM, Zhou X, Su D, Li H, Wang S, Michailidis IE, Tong L, Li X, Yang J. Structural basis of dual Ca(2+)/pH regulation of the endolysosomal TRPML1 channel. Nature Structural & Molecular Biology. PMID 28112729 DOI: 10.1038/nsmb.3362  0.44
2017 Wei J, Zhang Y, Yu TY, Sadre-Bazzaz K, Rudolph MJ, Amodeo GA, Symington LS, Walz T, Tong L. Erratum: A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation. Cell Discovery. 3: 16055. PMID 28101377 DOI: 10.1038/celldisc.2016.55  0.56
2017 Whiteley AT, Garelis NE, Peterson BN, Choi PH, Tong L, Woodward JJ, Portnoy DA. c-di-AMP modulates Listeria monocytogenes central metabolism to regulate growth, antibiotic resistance, and osmoregulation. Molecular Microbiology. PMID 28097715 DOI: 10.1111/mmi.13622  0.48
2016 Wei J, Zhang Y, Yu TY, Sadre-Bazzaz K, Rudolph MJ, Amodeo GA, Symington LS, Walz T, Tong L. A unified molecular mechanism for the regulation of acetyl-CoA carboxylase by phosphorylation. Cell Discovery. 2: 16044. PMID 27990296 DOI: 10.1038/celldisc.2016.44  0.56
2016 Liu Z, Gutierrez-Vargas C, Wei J, Grassucci RA, Ramesh M, Espina N, Sun M, Tutuncuoglu B, Madison-Antenucci S, Woolford JL, Tong L, Frank J. Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit. Proceedings of the National Academy of Sciences of the United States of America. 113: 12174-12179. PMID 27791004 DOI: 10.1073/pnas.1614594113  0.48
2016 Lewis-Ballester A, Forouhar F, Kim SM, Lew S, Wang Y, Karkashon S, Seetharaman J, Batabyal D, Chiang BY, Hussain M, Correia MA, Yeh SR, Tong L. Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase. Scientific Reports. 6: 35169. PMID 27762317 DOI: 10.1038/srep35169  0.72
2016 Liu Z, Gutierrez-Vargas C, Wei J, Grassucci RA, Espina N, Madison-Antenucci S, Tong L, Frank J. Determination of the ribosome structure to a resolution of 2.5 Å by single-particle cryo-EM. Protein Science : a Publication of the Protein Society. PMID 27750394 DOI: 10.1002/pro.3068  0.48
2016 Choi PH, Jo J, Lin YC, Lin MH, Chou CY, Dietrich LE, Tong L. A distinct holoenzyme organization for two-subunit pyruvate carboxylase. Nature Communications. 7: 12713. PMID 27708276 DOI: 10.1038/ncomms12713  1
2016 Shan CM, Wang J, Xu K, Chen H, Yue JX, Andrews S, Moresco JJ, Yates JR, Nagy PL, Tong L, Jia S. A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading. Elife. 5. PMID 27648579 DOI: 10.7554/eLife.17903  1
2016 Qiu C, Tong L, Yuan T, Wang F, Zhao F, Chen L. Constituents from Vitex negundo var. heterophylla and their inhibition of nitric oxide production. Journal of Natural Medicines. PMID 27535293 DOI: 10.1007/s11418-016-1032-y  0.4
2016 Zhang Y, Rataj K, Simpson GG, Tong L. Crystal Structure of the SPOC Domain of the Arabidopsis Flowering Regulator FPA. Plos One. 11: e0160694. PMID 27513867 DOI: 10.1371/journal.pone.0160694  0.48
2016 Huynh TN, Choi PH, Sureka K, Ledvina HE, Campillo J, Tong L, Woodward JJ. Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuC. Molecular Microbiology. PMID 27378384 DOI: 10.1111/mmi.13456  1
2016 Harriman G, Greenwood J, Bhat S, Huang X, Wang R, Paul D, Tong L, Saha AK, Westlin WF, Kapeller R, Harwood HJ. Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats. Proceedings of the National Academy of Sciences of the United States of America. PMID 26976583 DOI: 10.1073/pnas.1520686113  1
2015 Jurado AR, Huang CS, Zhang X, Zhou ZH, Tong L. Structure and substrate selectivity of the 750-kDa α6β6 holoenzyme of geranyl-CoA carboxylase. Nature Communications. 6: 8986. PMID 26593090 DOI: 10.1038/ncomms9986  1
2015 Wei J, Tong L. Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer. Nature. 526: 723-7. PMID 26458104 DOI: 10.1038/nature15375  1
2015 Katz FS, Pecic S, Tran TH, Trakht I, Schneider L, Zhu Z, Ton-That L, Luzac M, Zlatanic V, Damera S, Macdonald J, Landry DW, Tong L, Stojanovic MN. Discovery of New Classes of Compounds that Reactivate Acetylcholinesterase Inhibited by Organophosphates. Chembiochem : a European Journal of Chemical Biology. PMID 26350723 DOI: 10.1002/cbic.201500348  1
2015 Everett J, Tejero R, Murthy SB, Acton TB, Aramini JM, Baran MC, Benach J, Cort JR, Eletsky A, Forouhar F, Guan R, Kuzin AP, Lee HW, Liu G, Mani R, ... ... Tong L, et al. A Community Resource of Experimental Data for NMR - X-ray Crystal Structure Pairs. Protein Science : a Publication of the Protein Society. PMID 26293815 DOI: 10.1002/pro.2774  0.72
2015 Mompeán M, Hervás R, Xu Y, Tran TH, Guarnaccia C, Buratti E, Baralle F, Tong L, Carrión-Vázquez M, McDermott AE, Laurents DV. Structural Evidence of Amyloid Fibril Formation in the Putative Aggregation Domain of TDP-43. The Journal of Physical Chemistry Letters. 6: 2608-15. PMID 26266742 DOI: 10.1021/acs.jpclett.5b00918  0.32
2015 Wang VY, Jiao X, Kiledjian M, Tong L. Structural and biochemical studies of the distinct activity profiles of Rai1 enzymes. Nucleic Acids Research. PMID 26101253 DOI: 10.1093/nar/gkv620  1
2015 Webb BA, Forouhar F, Szu FE, Seetharaman J, Tong L, Barber DL. Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations. Nature. PMID 25985179 DOI: 10.1038/nature14405  1
2015 Tong L, Ma W, Liu H, Yuan C, Zhou Y. Simultaneous estimation of QTL effects and positions when using genotype data with errors. Journal of Genetics. 94: 27-34. PMID 25846874 DOI: 10.1007/s12041-015-0487-z  0.32
2015 Choi PH, Sureka K, Woodward JJ, Tong L. Molecular basis for the recognition of cyclic-di-AMP by PstA, a PII -like signal transduction protein. Microbiologyopen. 4: 361-74. PMID 25693966 DOI: 10.1002/mbo3.243  1
2015 Huynh TN, Luo S, Pensinger D, Sauer JD, Tong L, Woodward JJ. An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence. Proceedings of the National Academy of Sciences of the United States of America. 112: E747-56. PMID 25583510 DOI: 10.1073/pnas.1416485112  1
2015 Tran TH, Hsiao YS, Jo J, Chou CY, Dietrich LE, Walz T, Tong L. Structure and function of a single-chain, multi-domain long-chain acyl-CoA carboxylase. Nature. 518: 120-4. PMID 25383525 DOI: 10.1038/nature13912  1
2014 Lohman DC, Forouhar F, Beebe ET, Stefely MS, Minogue CE, Ulbrich A, Stefely JA, Sukumar S, Luna-Sánchez M, Jochem A, Lew S, Seetharaman J, Xiao R, Wang H, Westphall MS, ... ... Tong L, et al. Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 111: E4697-705. PMID 25339443 DOI: 10.1073/pnas.1413128111  1
2014 Sureka K, Choi PH, Precit M, Delince M, Pensinger DA, Huynh TN, Jurado AR, Goo YA, Sadilek M, Iavarone AT, Sauer JD, Tong L, Woodward JJ. The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function. Cell. 158: 1389-401. PMID 25215494 DOI: 10.1016/j.cell.2014.07.046  1
2014 Luo S, Tong L. Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain. Proceedings of the National Academy of Sciences of the United States of America. 111: 13834-9. PMID 25201973 DOI: 10.1073/pnas.1412742111  0.44
2014 Elshahawi SI, Ramelot TA, Seetharaman J, Chen J, Singh S, Yang Y, Pederson K, Kharel MK, Xiao R, Lew S, Yennamalli RM, Miller MD, Wang F, Tong L, Montelione GT, et al. Structure-guided functional characterization of enediyne self-sacrifice resistance proteins, CalU16 and CalU19. Acs Chemical Biology. 9: 2347-58. PMID 25079510 DOI: 10.1021/cb500327m  1
2014 Tan D, Zhou M, Kiledjian M, Tong L. The ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA. Nature Structural & Molecular Biology. 21: 679-85. PMID 25026078 DOI: 10.1038/nsmb.2857  1
2014 Zhang J, Tan D, DeRose EF, Perera L, Dominski Z, Marzluff WF, Tong L, Hall TM. Molecular mechanisms for the regulation of histone mRNA stem-loop-binding protein by phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 111: E2937-46. PMID 25002523 DOI: 10.1073/pnas.1406381111  1
2014 Lasso G, Yu LP, Gil D, Lázaro M, Tong L, Valle M. Functional conformations for pyruvate carboxylase during catalysis explored by cryoelectron microscopy. Structure (London, England : 1993). 22: 911-22. PMID 24882745 DOI: 10.1016/j.str.2014.04.011  1
2014 Wang R, Rajagopalan K, Sadre-Bazzaz K, Moreau M, Klessig DF, Tong L. Structure of the Arabidopsis thaliana TOP2 oligopeptidase. Acta Crystallographica. Section F, Structural Biology Communications. 70: 555-9. PMID 24817709 DOI: 10.1107/S2053230X14006128  1
2014 Yang X, Xu M, Wang Y, Xia P, Wang S, Ye B, Tong L, Jiang T, Fan Z. Molecular mechanism for self-protection against the type VI secretion system in Vibrio cholerae. Acta Crystallographica. Section D, Biological Crystallography. 70: 1094-103. PMID 24699653 DOI: 10.1107/S1399004714001242  0.4
2014 Jurado AR, Tan D, Jiao X, Kiledjian M, Tong L. Structure and function of pre-mRNA 5'-end capping quality control and 3'-end processing. Biochemistry. 53: 1882-98. PMID 24617759 DOI: 10.1021/bi401715v  1
2014 Xiang K, Tong L, Manley JL. Delineating the structural blueprint of the pre-mRNA 3'-end processing machinery. Molecular and Cellular Biology. 34: 1894-910. PMID 24591651 DOI: 10.1128/MCB.00084-14  1
2014 Srinivasan B, Forouhar F, Shukla A, Sampangi C, Kulkarni S, Abashidze M, Seetharaman J, Lew S, Mao L, Acton TB, Xiao R, Everett JK, Montelione GT, Tong L, Balaram H. Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila. The Febs Journal. 281: 1613-28. PMID 24456211 DOI: 10.1111/febs.12727  1
2014 Vorobiev SM, Gensler Y, Vahedian-Movahed H, Seetharaman J, Su M, Huang JY, Xiao R, Kornhaber G, Montelione GT, Tong L, Ebright RH, Nickels BE. Structure of the DNA-binding and RNA-polymerase-binding region of transcription antitermination factor λQ. Structure (London, England : 1993). 22: 488-95. PMID 24440517 DOI: 10.1016/j.str.2013.12.010  1
2014 Bjelic S, Kipnis Y, Wang L, Pianowski Z, Vorobiev S, Su M, Seetharaman J, Xiao R, Kornhaber G, Hunt JF, Tong L, Hilvert D, Baker D. Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design. Journal of Molecular Biology. 426: 256-71. PMID 24161950 DOI: 10.1016/j.jmb.2013.10.012  1
2013 Meng L, Forouhar F, Thieker D, Gao Z, Ramiah A, Moniz H, Xiang Y, Seetharaman J, Milaninia S, Su M, Bridger R, Veillon L, Azadi P, Kornhaber G, Wells L, ... ... Tong L, et al. Enzymatic basis for N-glycan sialylation: structure of rat α2,6-sialyltransferase (ST6GAL1) reveals conserved and unique features for glycan sialylation. The Journal of Biological Chemistry. 288: 34680-98. PMID 24155237 DOI: 10.1074/jbc.M113.519041  1
2013 Yang H, Zhang T, Tao Y, Wang F, Tong L, Ding J. Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair. Nucleic Acids Research. 41: 10573-83. PMID 24003026 DOI: 10.1093/nar/gkt788  0.4
2013 Neklesa TK, Noblin DJ, Kuzin A, Lew S, Seetharaman J, Acton TB, Kornhaber G, Xiao R, Montelione GT, Tong L, Crews CM. A bidirectional system for the dynamic small molecule control of intracellular fusion proteins. Acs Chemical Biology. 8: 2293-300. PMID 23978068 DOI: 10.1021/cb400569k  1
2013 Mills JH, Khare SD, Bolduc JM, Forouhar F, Mulligan VK, Lew S, Seetharaman J, Tong L, Stoddard BL, Baker D. Computational design of an unnatural amino acid dependent metalloprotein with atomic level accuracy. Journal of the American Chemical Society. 135: 13393-9. PMID 23924187 DOI: 10.1021/ja403503m  1
2013 Catalano J, Sadre-Bazzaz K, Amodeo GA, Tong L, McDermott A. Structural evidence: a single charged residue affects substrate binding in cytochrome P450 BM-3. Biochemistry. 52: 6807-15. PMID 23829560 DOI: 10.1021/bi4000645  1
2013 Procko E, Hedman R, Hamilton K, Seetharaman J, Fleishman SJ, Su M, Aramini J, Kornhaber G, Hunt JF, Tong L, Montelione GT, Baker D. Computational design of a protein-based enzyme inhibitor. Journal of Molecular Biology. 425: 3563-75. PMID 23827138 DOI: 10.1016/j.jmb.2013.06.035  1
2013 Froese DS, Forouhar F, Tran TH, Vollmar M, Kim YS, Lew S, Neely H, Seetharaman J, Shen Y, Xiao R, Acton TB, Everett JK, Cannone G, Puranik S, Savitsky P, ... ... Tong L, et al. Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations. Structure (London, England : 1993). 21: 1182-92. PMID 23791943 DOI: 10.1016/j.str.2013.05.001  1
2013 Tan D, Crabb WM, Whitman WB, Tong L. Crystal structure of DmdD, a crotonase superfamily enzyme that catalyzes the hydration and hydrolysis of methylthioacryloyl-CoA. Plos One. 8: e63870. PMID 23704947 DOI: 10.1371/journal.pone.0063870  0.52
2013 Jiao X, Chang JH, Kilic T, Tong L, Kiledjian M. A mammalian pre-mRNA 5' end capping quality control mechanism and an unexpected link of capping to pre-mRNA processing. Molecular Cell. 50: 104-15. PMID 23523372 DOI: 10.1016/j.molcel.2013.02.017  1
2013 Tan D, Marzluff WF, Dominski Z, Tong L. Structure of histone mRNA stem-loop, human stem-loop binding protein, and 3'hExo ternary complex. Science (New York, N.Y.). 339: 318-21. PMID 23329046 DOI: 10.1126/science.1228705  1
2013 Yu LP, Chou CY, Choi PH, Tong L. Characterizing the importance of the biotin carboxylase domain dimer for Staphylococcus aureus pyruvate carboxylase catalysis. Biochemistry. 52: 488-96. PMID 23286247 DOI: 10.1021/bi301294d  1
2013 Wang L, Li Q, Wu L, Liu S, Zhang Y, Yang X, Zhu P, Zhang H, Zhang K, Lou J, Liu P, Tong L, Sun F, Fan Z. Identification of SERPINB1 as a physiological inhibitor of human granzyme H. Journal of Immunology (Baltimore, Md. : 1950). 190: 1319-30. PMID 23269243 DOI: 10.4049/jimmunol.1202542  0.48
2013 Tong L. Structure and function of biotin-dependent carboxylases. Cellular and Molecular Life Sciences : Cmls. 70: 863-91. PMID 22869039 DOI: 10.1007/s00018-012-1096-0  1
2012 Chang JH, Xiang S, Tong L. Structures of 5'-3' Exoribonucleases. The Enzymes. 31: 115-29. PMID 27166443 DOI: 10.1016/B978-0-12-404740-2.00006-9  0.48
2012 Yu Y, Ulbrich MH, Li MH, Dobbins S, Zhang WK, Tong L, Isacoff EY, Yang J. Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex. Nature Communications. 3: 1252. PMID 23212381 DOI: 10.1038/ncomms2257  1
2012 Xiang K, Manley JL, Tong L. An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72. Genes & Development. 26: 2265-70. PMID 23070812 DOI: 10.1101/gad.198853.112  1
2012 de Crécy-Lagard V, Forouhar F, Brochier-Armanet C, Tong L, Hunt JF. Comparative genomic analysis of the DUF71/COG2102 family predicts roles in diphthamide biosynthesis and B12 salvage. Biology Direct. 7: 32. PMID 23013770 DOI: 10.1186/1745-6150-7-32  1
2012 Chang JH, Jiao X, Chiba K, Oh C, Martin CE, Kiledjian M, Tong L. Dxo1 is a new type of eukaryotic enzyme with both decapping and 5'-3' exoribonuclease activity. Nature Structural & Molecular Biology. 19: 1011-7. PMID 22961381 DOI: 10.1038/nsmb.2381  1
2012 Richter F, Blomberg R, Khare SD, Kiss G, Kuzin AP, Smith AJ, Gallaher J, Pianowski Z, Helgeson RC, Grjasnow A, Xiao R, Seetharaman J, Su M, Vorobiev S, Lew S, ... ... Tong L, et al. Computational design of catalytic dyads and oxyanion holes for ester hydrolysis. Journal of the American Chemical Society. 134: 16197-206. PMID 22871159 DOI: 10.1021/ja3037367  1
2012 Feldmann EA, Seetharaman J, Ramelot TA, Lew S, Zhao L, Hamilton K, Ciccosanti C, Xiao R, Acton TB, Everett JK, Tong L, Montelione GT, Kennedy MA. Solution NMR and X-ray crystal structures of Pseudomonas syringae Pspto_3016 from protein domain family PF04237 (DUF419) adopt a "double wing" DNA binding motif. Journal of Structural and Functional Genomics. 13: 155-62. PMID 22865330 DOI: 10.1007/s10969-012-9140-8  1
2012 Xiang K, Manley JL, Tong L. The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity. Nature Communications. 3: 946. PMID 22781759 DOI: 10.1038/ncomms1947  1
2012 Paulson AR, Tong L. Crystal structure of the Rna14-Rna15 complex. Rna (New York, N.Y.). 18: 1154-62. PMID 22513198 DOI: 10.1261/rna.032524.112  1
2012 Fan C, Chou CY, Tong L, Xiang S. Crystal structure of urea carboxylase provides insights into the carboxyltransfer reaction. The Journal of Biological Chemistry. 287: 9389-98. PMID 22277658 DOI: 10.1074/jbc.M111.319475  0.52
2012 Chang JH, Tong L. Mitochondrial poly(A) polymerase and polyadenylation. Biochimica Et Biophysica Acta. 1819: 992-7. PMID 22172994 DOI: 10.1016/j.bbagrm.2011.10.012  0.48
2012 Huang CS, Ge P, Zhou ZH, Tong L. An unanticipated architecture of the 750-kDa α6β6 holoenzyme of 3-methylcrotonyl-CoA carboxylase. Nature. 481: 219-23. PMID 22158123 DOI: 10.1038/nature10691  0.48
2012 Wang L, Zhang K, Wu L, Liu S, Zhang H, Zhou Q, Tong L, Sun F, Fan Z. Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif. Journal of Immunology (Baltimore, Md. : 1950). 188: 765-73. PMID 22156497 DOI: 10.4049/jimmunol.1101381  0.44
2012 Wang L, Guo H, Reyes N, Lee S, Bortz E, Guo F, Sun R, Tong L, Deng H. Distinct domains in ORF52 tegument protein mediate essential functions in murine gammaherpesvirus 68 virion tegumentation and secondary envelopment. Journal of Virology. 86: 1348-57. PMID 22090138 DOI: 10.1128/JVI.05497-11  0.32
2011 Aksyuk AA, Kurochkina LP, Fokine A, Forouhar F, Mesyanzhinov VV, Tong L, Rossmann MG. Structural conservation of the myoviridae phage tail sheath protein fold. Structure (London, England : 1993). 19: 1885-94. PMID 22153511 DOI: 10.1016/j.str.2011.09.012  1
2011 Forouhar F, Saadat N, Hussain M, Seetharaman J, Lee I, Janjua H, Xiao R, Shastry R, Acton TB, Montelione GT, Tong L. A large conformational change in the putative ATP pyrophosphatase PF0828 induced by ATP binding. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1323-7. PMID 22102225 DOI: 10.1107/S1744309111031447  0.72
2011 Kryshtafovych A, Moult J, Bartual SG, Bazan JF, Berman H, Casteel DE, Christodoulou E, Everett JK, Hausmann J, Heidebrecht T, Hills T, Hui R, Hunt JF, Seetharaman J, Joachimiak A, ... ... Tong L, et al. Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction. Proteins. 79: 6-20. PMID 22020785 DOI: 10.1002/prot.23196  1
2011 Lowery J, Szul T, Seetharaman J, Jian X, Su M, Forouhar F, Xiao R, Acton TB, Montelione GT, Lin H, Wright JW, Lee E, Holloway ZG, Randazzo PA, Tong L, et al. Novel C-terminal motif within Sec7 domain of guanine nucleotide exchange factors regulates ADP-ribosylation factor (ARF) binding and activation. The Journal of Biological Chemistry. 286: 36898-906. PMID 21828055 DOI: 10.1074/jbc.M111.230631  1
2011 Zhang H, Constantine R, Vorobiev S, Chen Y, Seetharaman J, Huang YJ, Xiao R, Montelione GT, Gerstner CD, Davis MW, Inana G, Whitby FG, Jorgensen EM, Hill CP, Tong L, et al. UNC119 is required for G protein trafficking in sensory neurons. Nature Neuroscience. 14: 874-80. PMID 21642972 DOI: 10.1038/nn.2835  1
2011 Chou CY, Tong L. Structural and biochemical studies on the regulation of biotin carboxylase by substrate inhibition and dimerization. The Journal of Biological Chemistry. 286: 24417-25. PMID 21592965 DOI: 10.1074/jbc.M111.220517  0.52
2011 Huang KY, Amodeo GA, Tong L, McDermott A. The structure of human ubiquitin in 2-methyl-2,4-pentanediol: a new conformational switch. Protein Science : a Publication of the Protein Society. 20: 630-9. PMID 21432937 DOI: 10.1002/pro.584  1
2011 Chang JH, Xiang S, Xiang K, Manley JL, Tong L. Structural and biochemical studies of the 5'→3' exoribonuclease Xrn1. Nature Structural & Molecular Biology. 18: 270-6. PMID 21297639 DOI: 10.1038/nsmb.1984  1
2011 Bai Y, Srivastava SK, Chang JH, Manley JL, Tong L. Structural basis for dimerization and activity of human PAPD1, a noncanonical poly(A) polymerase. Molecular Cell. 41: 311-20. PMID 21292163 DOI: 10.1016/j.molcel.2011.01.013  1
2011 Barb AW, Cort JR, Seetharaman J, Lew S, Lee HW, Acton T, Xiao R, Kennedy MA, Tong L, Montelione GT, Prestegard JH. Structures of domains I and IV from YbbR are representative of a widely distributed protein family. Protein Science : a Publication of the Protein Society. 20: 396-405. PMID 21154411 DOI: 10.1002/pro.571  1
2010 Forouhar F, Lew S, Seetharaman J, Xiao R, Acton TB, Montelione GT, Tong L. Structures of bacterial biosynthetic arginine decarboxylases. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1562-6. PMID 21139196 DOI: 10.1107/S1744309110040649  0.72
2010 Yu LP, Kim YS, Tong L. Mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by pinoxaden. Proceedings of the National Academy of Sciences of the United States of America. 107: 22072-7. PMID 21135213 DOI: 10.1073/pnas.1012039107  1
2010 Lasso G, Yu LP, Gil D, Xiang S, Tong L, Valle M. Cryo-EM analysis reveals new insights into the mechanism of action of pyruvate carboxylase. Structure (London, England : 1993). 18: 1300-10. PMID 20947019 DOI: 10.1016/j.str.2010.07.008  1
2010 Xiang K, Nagaike T, Xiang S, Kilic T, Beh MM, Manley JL, Tong L. Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex. Nature. 467: 729-33. PMID 20861839 DOI: 10.1038/nature09391  1
2010 Rudolph MJ, Amodeo GA, Tong L. An inhibited conformation for the protein kinase domain of the Saccharomyces cerevisiae AMPK homolog Snf1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 999-1002. PMID 20823513 DOI: 10.1107/S1744309110028265  1
2010 Jiao X, Xiang S, Oh C, Martin CE, Tong L, Kiledjian M. Identification of a quality-control mechanism for mRNA 5'-end capping. Nature. 467: 608-11. PMID 20802481 DOI: 10.1038/nature09338  1
2010 Huang CS, Sadre-Bazzaz K, Shen Y, Deng B, Zhou ZH, Tong L. Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase. Nature. 466: 1001-5. PMID 20725044 DOI: 10.1038/nature09302  0.48
2010 Manosalva PM, Park SW, Forouhar F, Tong L, Fry WE, Klessig DF. Methyl esterase 1 (StMES1) is required for systemic acquired resistance in potato. Molecular Plant-Microbe Interactions : Mpmi. 23: 1151-63. PMID 20687805 DOI: 10.1094/MPMI-23-9-1151  0.72
2010 Amodeo GA, Momcilovic M, Carlson M, Tong L. Biochemical and functional studies on the regulation of the Saccharomyces cerevisiae AMPK homolog SNF1. Biochemical and Biophysical Research Communications. 397: 197-201. PMID 20529674 DOI: 10.1016/j.bbrc.2010.05.083  1
2010 Corbett JW, Freeman-Cook KD, Elliott R, Vajdos F, Rajamohan F, Kohls D, Marr E, Zhang H, Tong L, Tu M, Murdande S, Doran SD, Houser JA, Song W, Jones CJ, et al. Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2. Bioorganic & Medicinal Chemistry Letters. 20: 2383-8. PMID 20219367 DOI: 10.1016/j.bmcl.2009.04.091  1
2009 Xiang S, Callaghan MM, Watson KG, Tong L. A different mechanism for the inhibition of the carboxyltransferase domain of acetyl-coenzyme A carboxylase by tepraloxydim. Proceedings of the National Academy of Sciences of the United States of America. 106: 20723-7. PMID 19926852 DOI: 10.1073/pnas.0908431106  0.44
2009 Sinturel F, Pellegrini O, Xiang S, Tong L, Condon C, Bénard L. Real-time fluorescence detection of exoribonucleases. Rna (New York, N.Y.). 15: 2057-62. PMID 19767421 DOI: 10.1261/rna.1670909  0.44
2009 Yu Y, Ulbrich MH, Li MH, Buraei Z, Chen XZ, Ong AC, Tong L, Isacoff EY, Yang J. Structural and molecular basis of the assembly of the TRPP2/PKD1 complex. Proceedings of the National Academy of Sciences of the United States of America. 106: 11558-63. PMID 19556541 DOI: 10.1073/pnas.0903684106  1
2009 Yu LP, Xiang S, Lasso G, Gil D, Valle M, Tong L. A symmetrical tetramer for S. aureus pyruvate carboxylase in complex with coenzyme A. Structure (London, England : 1993). 17: 823-32. PMID 19523900 DOI: 10.1016/j.str.2009.04.008  1
2009 Tao X, Tong L. Expression, purification, and crystallization of Toll/interleukin-1 receptor (TIR) domains. Methods in Molecular Biology (Clifton, N.J.). 517: 81-8. PMID 19378015 DOI: 10.1007/978-1-59745-541-1_6  0.8
2009 Hsiao YS, Parker D, Ratner AJ, Prince A, Tong L. Crystal structures of respiratory pathogen neuraminidases. Biochemical and Biophysical Research Communications. 380: 467-71. PMID 19284989 DOI: 10.1016/j.bbrc.2009.01.108  1
2009 Chou CY, Yu LP, Tong L. Crystal structure of biotin carboxylase in complex with substrates and implications for its catalytic mechanism. The Journal of Biological Chemistry. 284: 11690-7. PMID 19213731 DOI: 10.1074/jbc.M805783200  1
2009 Xiang S, Cooper-Morgan A, Jiao X, Kiledjian M, Manley JL, Tong L. Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1. Nature. 458: 784-8. PMID 19194460 DOI: 10.1038/nature07731  1
2009 Bertonati C, Punta M, Fischer M, Yachdav G, Forouhar F, Zhou W, Kuzin AP, Seetharaman J, Abashidze M, Ramelot TA, Kennedy MA, Cort JR, Belachew A, Hunt JF, Tong L, et al. Structural genomics reveals EVE as a new ASCH/PUA-related domain. Proteins. 75: 760-73. PMID 19191354 DOI: 10.1002/prot.22287  1
2009 Park SW, Liu PP, Forouhar F, Vlot AC, Tong L, Tietjen K, Klessig DF. Use of a synthetic salicylic acid analog to investigate the roles of methyl salicylate and its esterases in plant disease resistance. The Journal of Biological Chemistry. 284: 7307-17. PMID 19131332 DOI: 10.1074/jbc.M807968200  0.72
2008 Vila JA, Aramini JM, Rossi P, Kuzin A, Su M, Seetharaman J, Xiao R, Tong L, Montelione GT, Scheraga HA. Quantum chemical 13C(alpha) chemical shift calculations for protein NMR structure determination, refinement, and validation. Proceedings of the National Academy of Sciences of the United States of America. 105: 14389-94. PMID 18787110 DOI: 10.1073/pnas.0807105105  1
2008 Thackray SJ, Bruckmann C, Anderson JL, Campbell LP, Xiao R, Zhao L, Mowat CG, Forouhar F, Tong L, Chapman SK. Histidine 55 of tryptophan 2,3-dioxygenase is not an active site base but regulates catalysis by controlling substrate binding. Biochemistry. 47: 10677-84. PMID 18783250 DOI: 10.1021/bi801202a  1
2008 Huang YJ, Hang D, Lu LJ, Tong L, Gerstein MB, Montelione GT. Targeting the human cancer pathway protein interaction network by structural genomics. Molecular & Cellular Proteomics : McP. 7: 2048-60. PMID 18487680 DOI: 10.1074/mcp.M700550-MCP200  1
2008 Shen Y, Tong L. Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1. Biochemistry. 47: 5767-73. PMID 18452305 DOI: 10.1021/bi800314m  0.44
2008 Xiang S, Tong L. Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nature Structural & Molecular Biology. 15: 295-302. PMID 18297087 DOI: 10.1038/nsmb.1393  1
2008 Forouhar F, Abashidze M, Xu H, Grochowski LL, Seetharaman J, Hussain M, Kuzin A, Chen Y, Zhou W, Xiao R, Acton TB, Montelione GT, Galinier A, White RH, Tong L. Molecular insights into the biosynthesis of the F420 coenzyme. The Journal of Biological Chemistry. 283: 11832-40. PMID 18252724 DOI: 10.1074/jbc.M710352200  0.72
2008 Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, ... ... Tong L, et al. Protein production and purification. Nature Methods. 5: 135-46. PMID 18235434 DOI: 10.1038/nmeth.f.202  1
2007 Amodeo GA, Rudolph MJ, Tong L. Crystal structure of the heterotrimer core of Saccharomyces cerevisiae AMPK homologue SNF1. Nature. 449: 492-5. PMID 17851534 DOI: 10.1038/nature06127  1
2007 Bai Y, Auperin TC, Chou CY, Chang GG, Manley JL, Tong L. Crystal structure of murine CstF-77: dimeric association and implications for polyadenylation of mRNA precursors. Molecular Cell. 25: 863-75. PMID 17386263 DOI: 10.1016/j.molcel.2007.01.034  1
2007 Bai Y, Auperin TC, Tong L. The use of in situ proteolysis in the crystallization of murine CstF-77. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 135-8. PMID 17277459 DOI: 10.1107/S1744309107002904  1
2007 Rudolph MJ, Amodeo GA, Iram SH, Hong SP, Pirino G, Carlson M, Tong L. Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding. Structure (London, England : 1993). 15: 65-74. PMID 17223533 DOI: 10.1016/j.str.2006.11.014  1
2006 Hsiao YS, Jogl G, Tong L. Crystal structures of murine carnitine acetyltransferase in ternary complexes with its substrates. The Journal of Biological Chemistry. 281: 28480-7. PMID 16870616 DOI: 10.1074/jbc.M602622200  1
2006 Soong G, Muir A, Gomez MI, Waks J, Reddy B, Planet P, Singh PK, Kaneko Y, Kanetko Y, Wolfgang MC, Hsiao YS, Tong L, Prince A. Bacterial neuraminidase facilitates mucosal infection by participating in biofilm production. The Journal of Clinical Investigation. 116: 2297-2305. PMID 16862214 DOI: 10.1172/JCI27920  1
2006 Hsiao YS, Jogl G, Esser V, Tong L. Crystal structure of rat carnitine palmitoyltransferase II (CPT-II). Biochemical and Biophysical Research Communications. 346: 974-80. PMID 16781677 DOI: 10.1016/j.bbrc.2006.06.006  1
2006 Annedi SC, Biabani F, Poduch E, Mannargudi BM, Majumder K, Wei L, Khayat R, Tong L, Kotra LP. Engineering d-amino acid containing novel protease inhibitors using catalytic site architecture. Bioorganic & Medicinal Chemistry. 14: 214-36. PMID 16198572 DOI: 10.1016/j.bmc.2005.08.019  1
2005 Rudolph MJ, Amodeo GA, Bai Y, Tong L. Crystal structure of the protein kinase domain of yeast AMP-activated protein kinase Snf1. Biochemical and Biophysical Research Communications. 337: 1224-8. PMID 16236260 DOI: 10.1016/j.bbrc.2005.09.181  1
2005 Jogl G, Hsiao YS, Tong L. Crystal structure of mouse carnitine octanoyltransferase and molecular determinants of substrate selectivity. The Journal of Biological Chemistry. 280: 738-44. PMID 15492013 DOI: 10.1074/jbc.M409894200  1
2004 Jogl G, Hsiao YS, Tong L. Structure and function of carnitine acyltransferases. Annals of the New York Academy of Sciences. 1033: 17-29. PMID 15591000 DOI: 10.1196/annals.1320.002  1
2004 Hsiao YS, Jogl G, Tong L. Structural and biochemical studies of the substrate selectivity of carnitine acetyltransferase. The Journal of Biological Chemistry. 279: 31584-9. PMID 15155726 DOI: 10.1074/jbc.M403484200  1
2004 Khayat R, Batra R, Bebernitz GA, Olson MW, Tong L. Characterization of the monomer-dimer equilibrium of human cytomegalovirus protease by kinetic methods. Biochemistry. 43: 316-22. PMID 14717585 DOI: 10.1021/bi035170d  1
2003 Tao X, Yang Z, Tong L. Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism. Structure (London, England : 1993). 11: 1141-50. PMID 12962632  0.8
2003 Tao X, Khayat R, Christendat D, Savchenko A, Xu X, Goldsmith-Fischman S, Honig B, Edwards A, Arrowsmith CH, Tong L. Crystal structures of MTH1187 and its yeast ortholog YBL001c. Proteins. 52: 478-80. PMID 12866058 DOI: 10.1002/prot.10443  1
2003 Zhang H, Yang Z, Shen Y, Tong L. Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase. Science (New York, N.Y.). 299: 2064-7. PMID 12663926 DOI: 10.1126/science.1081366  0.8
2003 Khayat R, Batra R, Qian C, Halmos T, Bailey M, Tong L. Structural and biochemical studies of inhibitor binding to human cytomegalovirus protease. Biochemistry. 42: 885-91. PMID 12549906 DOI: 10.1021/bi027045s  1
2003 Yang Z, Savchenko A, Yakunin A, Zhang R, Edwards A, Arrowsmith C, Tong L. Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643. The Journal of Biological Chemistry. 278: 8804-8. PMID 12496312 DOI: 10.1074/jbc.M211892200  1
2002 Yang Z, Zhang H, Hung HC, Kuo CC, Tsai LC, Yuan HS, Chou WY, Chang GG, Tong L. Structural studies of the pigeon cytosolic NADP(+)-dependent malic enzyme. Protein Science : a Publication of the Protein Society. 11: 332-41. PMID 11790843 DOI: 10.1110/ps.38002  0.8
1997 Tong L, Rossmann MG. [34] Rotation function calculations with GLRF program. Methods in Enzymology. 276: 594-611. PMID 27799117 DOI: 10.1016/S0076-6879(97)76080-4  0.96
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