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Patricia A. Jennings - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
protein structure, dynamics and folding; 2, 3 and 4D NMR spectroscopy; PCR; equilibrium and kinetic-fluorescence, absorbance and circular dichroism spectroscopies
Website:
http://www-chem.ucsd.edu/faculty/profiles/jennings_patricia_a.html

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Capraro DT, Burban DJ, Jennings PA. Unraveling Allostery in a Knotted Minimal Methyltransferase by NMR Spectroscopy. Journal of Molecular Biology. PMID 32135193 DOI: 10.1016/J.Jmb.2020.02.029  1
2019 Lipper CH, Stofleth JT, Bai F, Sohn YS, Roy S, Mittler R, Nechushtai R, Onuchic JN, Jennings PA. Redox-dependent gating of VDAC by mitoNEET. Proceedings of the National Academy of Sciences of the United States of America. PMID 31527235 DOI: 10.1073/Pnas.1908271116  0.56
2019 Lee JH, Hailey KL, Vitorino SA, Jennings PA, Bigby TD, Breen EC. Cigarette Smoke Triggers IL-33-Associated Inflammation in a Model of Late Stage COPD. American Journal of Respiratory Cell and Molecular Biology. PMID 30973786 DOI: 10.1165/Rcmb.2018-0402Oc  0.68
2019 Iosub-Amir A, Bai F, Sohn YS, Song L, Tamir S, Marjault HB, Mayer G, Karmi O, Jennings PA, Mittler R, Onuchic JN, Friedler A, Nechushtai R. The anti-apoptotic proteins NAF-1 and iASPP interact to drive apoptosis in cancer cells. Chemical Science. 10: 665-673. PMID 30774867 DOI: 10.1039/C8Sc03390K  0.56
2018 Cheng RR, Haglund E, Tiee NS, Morcos F, Levine H, Adams JA, Jennings PA, Onuchic JN. Designing bacterial signaling interactions with coevolutionary landscapes. Plos One. 13: e0201734. PMID 30125296 DOI: 10.1371/Journal.Pone.0201734  0.68
2018 Sengupta S, Nechushtai R, Jennings PA, Onuchic JN, Padilla PA, Azad RK, Mittler R. Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin. Scientific Reports. 8: 4840. PMID 29556009 DOI: 10.1038/S41598-018-23305-6  0.56
2018 Mittler R, Darash-Yahana M, Sohn YS, Bai F, Song L, Cabantchik IZ, Jennings P, Onuchic J, Nechushtai R. NEET proteins: A new link between iron metabolism, ROS and cancer. Antioxidants & Redox Signaling. PMID 29463105 DOI: 10.1089/Ars.2018.7502  0.4
2018 Karmi O, Marjault HB, Pesce L, Carloni P, Onuchic JN, Jennings PA, Mittler R, Nechushtai R. The unique fold and lability of the [2Fe-2S] clusters of NEET proteins mediate their key functions in health and disease. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 29435647 DOI: 10.1007/S00775-018-1538-8  0.56
2017 Lipper CH, Karmi O, Sohn YS, Darash-Yahana M, Lammert H, Song L, Liu A, Mittler R, Nechushtai R, Onuchic JN, Jennings PA. Structure of the human monomeric NEET protein MiNT and its role in regulating iron and reactive oxygen species in cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 29259115 DOI: 10.1073/Pnas.1715842115  0.56
2017 Pesce L, Calandrini V, Marjault HB, Lipper CH, Rossetti G, Mittler R, Jennings PA, Bauer A, Nechushtai R, Carloni P. Molecular Dynamics Simulations of the [2Fe-2S] Cluster-Binding Domain of NEET Proteins Reveal Key Molecular Determinants That Induce Their Cluster Transfer/Release. The Journal of Physical Chemistry. B. PMID 29086562 DOI: 10.1021/Acs.Jpcb.7B10584  0.4
2017 Aubol BE, Hailey KL, Fattet L, Jennings PA, Adams JA. Redirecting SR Protein Nuclear Trafficking Through An Allosteric Platform. Journal of Molecular Biology. PMID 28576472 DOI: 10.1016/J.Jmb.2017.05.022  0.68
2017 Karmi O, Holt SH, Song L, Tamir S, Luo Y, Bai F, Adenwalla A, Darash-Yahana M, Sohn YS, Jennings PA, Azad RK, Onuchic JN, Morcos F, Nechushtai R, Mittler R. Interactions between mitoNEET and NAF-1 in cells. Plos One. 12: e0175796. PMID 28426722 DOI: 10.1371/Journal.Pone.0175796  0.56
2017 Burban DJ, Jennings PA. Backbone assignments for the SPOUT methyltransferase MTT Tm , a knotted protein from Thermotoga maritima. Biomolecular Nmr Assignments. PMID 28284017 DOI: 10.1007/S12104-017-9737-8  0.96
2017 Inupakutika MA, Sengupta S, Nechushtai R, Jennings PA, Onuchic JN, Azad RK, Padilla P, Mittler R. Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates. Scientific Reports. 7: 42571. PMID 28205535 DOI: 10.1038/Srep42571  0.56
2016 Darash-Yahana M, Pozniak Y, Lu M, Sohn YS, Karmi O, Tamir S, Bai F, Song L, Jennings PA, Pikarsky E, Geiger T, Onuchic JN, Mittler R, Nechushtai R. Breast cancer tumorigenicity is dependent on high expression levels of NAF-1 and the lability of its Fe-S clusters. Proceedings of the National Academy of Sciences of the United States of America. PMID 27621439 DOI: 10.1073/Pnas.1612736113  1
2016 Yim KH, Prince TL, Qu S, Bai F, Jennings PA, Onuchic JN, Theodorakis EA, Neckers L. Gambogic acid identifies an isoform-specific druggable pocket in the middle domain of Hsp90β. Proceedings of the National Academy of Sciences of the United States of America. PMID 27466407 DOI: 10.1073/Pnas.1606655113  1
2016 Capraro DT, Jennings PA. Untangling the Influence of a Protein Knot on Folding. Biophysical Journal. 110: 1044-1051. PMID 26958882 DOI: 10.1016/J.Bpj.2016.01.017  1
2015 Fisher KM, Haglund E, Noel JK, Hailey KL, Onuchic JN, Jennings PA. Geometrical Frustration in Interleukin-33 Decouples the Dynamics of the Functional Element from the Folding Transition State Ensemble. Plos One. 10: e0144067. PMID 26630011 DOI: 10.1371/Journal.Pone.0144067  1
2015 Holt SH, Darash-Yahana M, Sohn YS, Song L, Karmi O, Tamir S, Michaeli D, Luo Y, Paddock ML, Jennings PA, Onuchic JN, Azad RK, Pikarsky E, Cabantchik IZ, Nechushtai R, et al. Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells. Journal of Cell Science. PMID 26621032 DOI: 10.1242/Jcs.178293  0.56
2015 Lipper CH, Paddock ML, Onuchic JN, Mittler R, Nechushtai R, Jennings PA. Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis. Plos One. 10: e0139699. PMID 26448442 DOI: 10.1371/Journal.Pone.0139699  1
2015 Keshwani MM, Hailey KL, Aubol BE, Fattet L, McGlone ML, Jennings PA, Adams JA. Nuclear Protein Kinase CLK1 Uses A Nontraditional Docking Mechanism To Select Physiological Substrates. The Biochemical Journal. PMID 26443864 DOI: 10.1042/Bj20150903  0.44
2015 Burban DJ, Haglund E, Capraro DT, Jennings PA. Heterogeneous side chain conformation highlights a network of interactions implicated in hysteresis of the knotted protein, minimal tied trefoil. Journal of Physics. Condensed Matter : An Institute of Physics Journal. 27: 354108. PMID 26291198 DOI: 10.1088/0953-8984/27/35/354108  0.44
2015 Barkho S, Pierce LC, Li S, Adams JA, Jennings PA. Correction: Theoretical Insights Reveal Novel Motions in Csk's SH3 Domain That Control Kinase Activation. Plos One. 10: e0133801. PMID 26191813 DOI: 10.1371/Journal.Pone.0133801  0.68
2015 Barkho S, Pierce LC, Li S, Adams JA, Jennings PA. Theoretical Insights Reveal Novel Motions in Csk's SH3 Domain That Control Kinase Activation. Plos One. 10: e0127724. PMID 26030592 DOI: 10.1371/Journal.Pone.0127724  1
2015 Daniel KB, Sullivan ED, Chen Y, Chan JC, Jennings PA, Fierke CA, Cohen SM. Dual-Mode HDAC Prodrug for Covalent Modification and Subsequent Inhibitor Release. Journal of Medicinal Chemistry. 58: 4812-21. PMID 25974739 DOI: 10.1021/Acs.Jmedchem.5B00539  0.44
2015 Bai F, Morcos F, Sohn YS, Darash-Yahana M, Rezende CO, Lipper CH, Paddock ML, Song L, Luo Y, Holt SH, Tamir S, Theodorakis EA, Jennings PA, Onuchic JN, Mittler R, et al. The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 112: 3698-703. PMID 25762074 DOI: 10.1073/Pnas.1502960112  1
2015 Keshwani MM, Aubol BE, Fattet L, Ma CT, Qiu J, Jennings PA, Fu XD, Adams JA. Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function. The Biochemical Journal. 466: 311-22. PMID 25529026 DOI: 10.1042/Bj20141373  1
2015 Tamir S, Paddock ML, Darash-Yahana-Baram M, Holt SH, Sohn YS, Agranat L, Michaeli D, Stofleth JT, Lipper CH, Morcos F, Cabantchik IZ, Onuchic JN, Jennings PA, Mittler R, Nechushtai R. Structure-function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease. Biochimica Et Biophysica Acta. 1853: 1294-1315. PMID 25448035 DOI: 10.1016/J.Bbamcr.2014.10.014  1
2014 Haglund E, Sulkowska JI, Noel JK, Lammert H, Onuchic JN, Jennings PA. Pierced Lasso Bundles are a new class of knot-like motifs. Plos Computational Biology. 10: e1003613. PMID 24945798 DOI: 10.1371/Journal.Pcbi.1003613  1
2014 Tamir S, Eisenberg-Domovich Y, Conlan AR, Stofleth JT, Lipper CH, Paddock ML, Mittler R, Jennings PA, Livnah O, Nechushtai R. A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties. Acta Crystallographica. Section D, Biological Crystallography. 70: 1572-8. PMID 24914968 DOI: 10.1107/S1399004714005458  1
2014 Tamir S, Rotem-Bamberger S, Katz C, Morcos F, Hailey KL, Zuris JA, Wang C, Conlan AR, Lipper CH, Paddock ML, Mittler R, Onuchic JN, Jennings PA, Friedler A, Nechushtai R. Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1. Proceedings of the National Academy of Sciences of the United States of America. 111: 5177-82. PMID 24706857 DOI: 10.1073/Pnas.1403770111  1
2014 Xiang Z, Lacey VK, Ren H, Xu J, Burban DJ, Jennings PA, Wang L. Proximity-enabled protein crosslinking through genetically encoding haloalkane unnatural amino acids. Angewandte Chemie (International Ed. in English). 53: 2190-3. PMID 24449339 DOI: 10.1002/Anie.201308794  1
2013 Barkho S, Pierce LC, McGlone ML, Li S, Woods VL, Walker RC, Adams JA, Jennings PA. Distal loop flexibility of a regulatory domain modulates dynamics and activity of C-terminal SRC kinase (csk). Plos Computational Biology. 9: e1003188. PMID 24039559 DOI: 10.1371/Journal.Pcbi.1003188  1
2013 Capraro DT, Lammert H, Heidary DK, Roy M, Gross LA, Onuchic JN, Jennings PA. Altered backbone and side-chain interactions result in route heterogeneity during the folding of interleukin-1β (IL-1β). Biophysical Journal. 105: 975-83. PMID 23972849 DOI: 10.1016/J.Bpj.2013.06.019  1
2013 Sohn YS, Tamir S, Song L, Michaeli D, Matouk I, Conlan AR, Harir Y, Holt SH, Shulaev V, Paddock ML, Hochberg A, Cabanchick IZ, Onuchic JN, Jennings PA, Nechushtai R, et al. NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 110: 14676-81. PMID 23959881 DOI: 10.1073/Pnas.1313198110  1
2013 Tamir S, Zuris JA, Agranat L, Lipper CH, Conlan AR, Michaeli D, Harir Y, Paddock ML, Mittler R, Cabantchik ZI, Jennings PA, Nechushtai R. Nutrient-deprivation autophagy factor-1 (NAF-1): biochemical properties of a novel cellular target for anti-diabetic drugs. Plos One. 8: e61202. PMID 23717386 DOI: 10.1371/Journal.Pone.0061202  1
2013 Andrews BT, Capraro DT, Sulkowska JI, Onuchic JN, Jennings PA. Hysteresis as a Marker for Complex, Overlapping Landscapes in Proteins. The Journal of Physical Chemistry Letters. 4: 180-188. PMID 23525263 DOI: 10.1021/Jz301893W  1
2013 Hailey KL, Capraro DT, Barkho S, Jennings PA. Allosteric switching of agonist/antagonist activity by a single point mutation in the interluekin-1 receptor antagonist, IL-1Ra. Journal of Molecular Biology. 425: 2382-92. PMID 23499887 DOI: 10.1016/J.Jmb.2013.03.016  1
2013 Onuchic JN, Jennings PA, Ben-Jacob E. Learning from cancer how to defeat bacteria. Proceedings of the National Academy of Sciences of the United States of America. 110: 3212-3. PMID 23407166 DOI: 10.1073/Pnas.1222882110  1
2013 Baxter EL, Zuris JA, Wang C, Vo PL, Axelrod HL, Cohen AE, Paddock ML, Nechushtai R, Onuchic JN, Jennings PA. Allosteric control in a metalloprotein dramatically alters function. Proceedings of the National Academy of Sciences of the United States of America. 110: 948-53. PMID 23271805 DOI: 10.1073/Pnas.1208286110  1
2012 Haglund E, SuÅ‚kowska JI, He Z, Feng GS, Jennings PA, Onuchic JN. The unique cysteine knot regulates the pleotropic hormone leptin. Plos One. 7: e45654. PMID 23029163 DOI: 10.1371/Journal.Pone.0045654  1
2012 Jamros MA, Oliveira LC, Whitford PC, Onuchic JN, Adams JA, Jennings PA. Substrate-specific reorganization of the conformational ensemble of CSK implicates novel modes of kinase function. Plos Computational Biology. 8: e1002695. PMID 23028292 DOI: 10.1371/Journal.Pcbi.1002695  1
2012 Capraro DT, Gosavi S, Roy M, Onuchic JN, Jennings PA. Folding circular permutants of IL-1β: route selection driven by functional frustration. Plos One. 7: e38512. PMID 22693643 DOI: 10.1371/Journal.Pone.0038512  1
2012 Nechushtai R, Conlan AR, Harir Y, Song L, Yogev O, Eisenberg-Domovich Y, Livnah O, Michaeli D, Rosen R, Ma V, Luo Y, Zuris JA, Paddock ML, Cabantchik ZI, Jennings PA, et al. Characterization of Arabidopsis NEET reveals an ancient role for NEET proteins in iron metabolism. The Plant Cell. 24: 2139-54. PMID 22562611 DOI: 10.1105/Tpc.112.097634  1
2012 Zuris JA, Ali SS, Yeh H, Nguyen TA, Nechushtai R, Paddock ML, Jennings PA. NADPH inhibits [2Fe-2S] cluster protein transfer from diabetes drug target MitoNEET to an apo-acceptor protein. The Journal of Biological Chemistry. 287: 11649-55. PMID 22351774 DOI: 10.1074/Jbc.M111.319731  1
2012 Abrahamsen H, O'Neill AK, Kannan N, Kruse N, Taylor SS, Jennings PA, Newton AC. Peptidyl-prolyl isomerase Pin1 controls down-regulation of conventional protein kinase C isozymes. The Journal of Biological Chemistry. 287: 13262-78. PMID 22318721 DOI: 10.1074/Jbc.M112.349753  1
2012 Baxter EL, Jennings PA, Onuchic JN. Strand swapping regulates the iron-sulfur cluster in the diabetes drug target mitoNEET. Proceedings of the National Academy of Sciences of the United States of America. 109: 1955-60. PMID 22308404 DOI: 10.1073/Pnas.1116369109  1
2012 Capraro DT, Roy M, Onuchic JN, Gosavi S, Jennings PA. β-Bulge triggers route-switching on the functional landscape of interleukin-1β. Proceedings of the National Academy of Sciences of the United States of America. 109: 1490-3. PMID 22307602 DOI: 10.1073/Pnas.1114430109  1
2011 Zuris JA, Harir Y, Conlan AR, Shvartsman M, Michaeli D, Tamir S, Paddock ML, Onuchic JN, Mittler R, Cabantchik ZI, Jennings PA, Nechushtai R. Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor protein. Proceedings of the National Academy of Sciences of the United States of America. 108: 13047-52. PMID 21788481 DOI: 10.1073/Pnas.1109986108  1
2011 Conlan AR, Paddock ML, Homer C, Axelrod HL, Cohen AE, Abresch EC, Zuris JA, Nechushtai R, Jennings PA. Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conformational heterogeneity in the ligand environment. Acta Crystallographica. Section D, Biological Crystallography. 67: 516-23. PMID 21636891 DOI: 10.1107/S0907444911011577  1
2011 Plocinik RM, Li S, Liu T, Hailey KL, Whitesides J, Whitehouse J, Ma CT, Fu XD, Gosh G, Woods VL, Jennings PA, Adams JA. Regulating SR protein phosphorylation through regions outside the kinase domain of SRPK1. Journal of Molecular Biology. 410: 131-45. PMID 21600902 DOI: 10.1016/J.Jmb.2011.04.077  1
2011 Baxter EL, Jennings PA, Onuchic JN. Interdomain communication revealed in the diabetes drug target mitoNEET. Proceedings of the National Academy of Sciences of the United States of America. 108: 5266-71. PMID 21402934 DOI: 10.1073/Pnas.1017604108  1
2011 Nechushtai R, Lammert H, Michaeli D, Eisenberg-Domovich Y, Zuris JA, Luca MA, Capraro DT, Fish A, Shimshon O, Roy M, Schug A, Whitford PC, Livnah O, Onuchic JN, Jennings PA. Allostery in the ferredoxin protein motif does not involve a conformational switch. Proceedings of the National Academy of Sciences of the United States of America. 108: 2240-5. PMID 21266547 DOI: 10.1073/Pnas.1019502108  1
2010 Zuris JA, Halim DA, Conlan AR, Abresch EC, Nechushtai R, Paddock ML, Jennings PA. Engineering the redox potential over a wide range within a new class of FeS proteins. Journal of the American Chemical Society. 132: 13120-2. PMID 20812736 DOI: 10.1021/Ja103920K  1
2010 Jamros MA, Oliveira LC, Whitford PC, Onuchic JN, Adams JA, Blumenthal DK, Jennings PA. Proteins at work: a combined small angle X-RAY scattering and theoretical determination of the multiple structures involved on the protein kinase functional landscape. The Journal of Biological Chemistry. 285: 36121-8. PMID 20801888 DOI: 10.1074/Jbc.M110.116947  1
2010 Plesniak LA, Salzameda B, Hinderberger H, Regan E, Kahn J, Mills SA, Teriete P, Yao Y, Jennings P, Marassi F, Adams JA. Structure and activity of CPNGRC: a modified CD13/APN peptidic homing motif. Chemical Biology & Drug Design. 75: 551-62. PMID 20374250 DOI: 10.1111/J.1747-0285.2010.00974.X  1
2010 Dicus MM, Conlan A, Nechushtai R, Jennings PA, Paddock ML, Britt RD, Stoll S. Binding of histidine in the (Cys)3(His)1-coordinated [2Fe-2S] cluster of human mitoNEET. Journal of the American Chemical Society. 132: 2037-49. PMID 20099820 DOI: 10.1021/Ja909359G  1
2009 Bak DW, Zuris JA, Paddock ML, Jennings PA, Elliott SJ. Redox characterization of the FeS protein MitoNEET and impact of thiazolidinedione drug binding. Biochemistry. 48: 10193-5. PMID 19791753 DOI: 10.1021/Bi9016445  1
2009 Hailey KL, Li S, Andersen MD, Roy M, Woods VL, Jennings PA. Pro-interleukin (IL)-1beta shares a core region of stability as compared with mature IL-1beta while maintaining a distinctly different configurational landscape: a comparative hydrogen/deuterium exchange mass spectrometry study. The Journal of Biological Chemistry. 284: 26137-48. PMID 19592498 DOI: 10.1074/Jbc.M109.027375  1
2009 Conlan AR, Axelrod HL, Cohen AE, Abresch EC, Zuris J, Yee D, Nechushtai R, Jennings PA, Paddock ML. Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2. Journal of Molecular Biology. 392: 143-53. PMID 19580816 DOI: 10.1016/J.Jmb.2009.06.079  1
2009 Andrews BT, Roy M, Jennings PA. Chromophore packing leads to hysteresis in GFP. Journal of Molecular Biology. 392: 218-27. PMID 19577576 DOI: 10.1016/J.Jmb.2009.06.072  1
2009 Conlan AR, Paddock ML, Axelrod HL, Cohen AE, Abresch EC, Wiley S, Roy M, Nechushtai R, Jennings PA. The novel 2Fe-2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 654-9. PMID 19574633 DOI: 10.1107/S1744309109019605  1
2009 Tirrell TF, Paddock ML, Conlan AR, Smoll EJ, Nechushtai R, Jennings PA, Kim JE. Resonance Raman studies of the (His)(Cys)3 2Fe-2S cluster of MitoNEET: comparison to the (Cys)4 mutant and implications of the effects of pH on the labile metal center. Biochemistry. 48: 4747-52. PMID 19388667 DOI: 10.1021/Bi900028R  1
2009 Hyeon C, Jennings PA, Adams JA, Onuchic JN. Ligand-induced global transitions in the catalytic domain of protein kinase A. Proceedings of the National Academy of Sciences of the United States of America. 106: 3023-8. PMID 19204278 DOI: 10.1073/Pnas.0813266106  1
2008 Capraro DT, Roy M, Onuchic JN, Jennings PA. Backtracking on the folding landscape of the beta-trefoil protein interleukin-1beta? Proceedings of the National Academy of Sciences of the United States of America. 105: 14844-8. PMID 18806223 DOI: 10.1073/Pnas.0807812105  1
2008 Andrews BT, Gosavi S, Finke JM, Onuchic JN, Jennings PA. The dual-basin landscape in GFP folding. Proceedings of the National Academy of Sciences of the United States of America. 105: 12283-8. PMID 18713871 DOI: 10.1073/Pnas.0804039105  1
2008 Hagopian JC, Ma CT, Meade BR, Albuquerque CP, Ngo JC, Ghosh G, Jennings PA, Fu XD, Adams JA. Adaptable molecular interactions guide phosphorylation of the SR protein ASF/SF2 by SRPK1. Journal of Molecular Biology. 382: 894-909. PMID 18687337 DOI: 10.1016/J.Jmb.2008.07.055  1
2008 Gosavi S, Whitford PC, Jennings PA, Onuchic JN. Extracting function from a beta-trefoil folding motif. Proceedings of the National Academy of Sciences of the United States of America. 105: 10384-9. PMID 18650393 DOI: 10.1073/Pnas.0801343105  1
2008 Plesniak LA, Botsch K, Leibrand M, Kelly M, Sem D, Adams JA, Jennings P. Transferred NOE and saturation transfer difference NMR studies of novobiocin binding to EnvZ suggest binding mode similar to DNA gyrase. Chemical Biology & Drug Design. 71: 28-35. PMID 18093089 DOI: 10.1111/J.1747-0285.2007.00607.X  1
2008 Gosavi S, Whitford PC, Jennings PA, Onuchic JN. Extracting function from a β-trefoil folding motif (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, 30 (11384-10389) DOI: 10.1073/pnas.0801343105)) Proceedings of the National Academy of Sciences of the United States of America. 105: 16057. DOI: 10.1073/pnas.0808551105  1
2007 Andrews BT, Schoenfish AR, Roy M, Waldo G, Jennings PA. The rough energy landscape of superfolder GFP is linked to the chromophore. Journal of Molecular Biology. 373: 476-90. PMID 17822714 DOI: 10.1016/J.Jmb.2007.07.071  1
2007 Paddock ML, Wiley SE, Axelrod HL, Cohen AE, Roy M, Abresch EC, Capraro D, Murphy AN, Nechushtai R, Dixon JE, Jennings PA. MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone. Proceedings of the National Academy of Sciences of the United States of America. 104: 14342-7. PMID 17766440 DOI: 10.1073/Pnas.0707189104  1
2007 Wiley SE, Paddock ML, Abresch EC, Gross L, van der Geer P, Nechushtai R, Murphy AN, Jennings PA, Dixon JE. The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster. The Journal of Biological Chemistry. 282: 23745-9. PMID 17584744 DOI: 10.1074/Jbc.C700107200  1
2007 Finke JM, Jennings PA, Lee JC, Onuchic JN, Winkler JR. Equilibrium unfolding of the poly(glutamic acid)20 helix. Biopolymers. 86: 193-211. PMID 17370320 DOI: 10.1002/Bip.20719  1
2007 Mills JE, Whitford PC, Shaffer J, Onuchic JN, Adams JA, Jennings PA. A novel disulfide bond in the SH2 Domain of the C-terminal Src kinase controls catalytic activity. Journal of Molecular Biology. 365: 1460-8. PMID 17137590 DOI: 10.1016/J.Jmb.2006.10.076  1
2006 Kinderman FS, Kim C, von Daake S, Ma Y, Pham BQ, Spraggon G, Xuong NH, Jennings PA, Taylor SS. A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase. Molecular Cell. 24: 397-408. PMID 17081990 DOI: 10.1016/J.Molcel.2006.09.015  1
2006 Sandoval CM, Geierstanger BH, Fujimura S, Balatbat C, Williams T, de Unamuno J, Whiles-Lillig JA, Ellerby LM, Ellerby HM, Jennings P, Plesniak LA. Structural evaluation of a novel pro-apoptotic peptide coupled to CNGRC tumor homing sequence by NMR. Chemical Biology & Drug Design. 67: 417-24. PMID 16882316 DOI: 10.1111/J.1747-0285.2006.00394.X  1
2006 Onuchic JN, Kobayashi C, Miyashita O, Jennings P, Baldridge KK. Exploring biomolecular machines: energy landscape control of biological reactions. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 361: 1439-43. PMID 16873130 DOI: 10.1098/Rstb.2006.1876  1
2006 Chavez LL, Gosavi S, Jennings PA, Onuchic JN. Multiple routes lead to the native state in the energy landscape of the beta-trefoil family. Proceedings of the National Academy of Sciences of the United States of America. 103: 10254-8. PMID 16801558 DOI: 10.1073/Pnas.0510110103  1
2006 Gosavi S, Chavez LL, Jennings PA, Onuchic JN. Topological frustration and the folding of interleukin-1 beta. Journal of Molecular Biology. 357: 986-96. PMID 16469330 DOI: 10.1016/J.Jmb.2005.11.074  1
2005 Burns-Hamuro LL, Hamuro Y, Kim JS, Sigala P, Fayos R, Stranz DD, Jennings PA, Taylor SS, Woods VL. Distinct interaction modes of an AKAP bound to two regulatory subunit isoforms of protein kinase A revealed by amide hydrogen/deuterium exchange. Protein Science : a Publication of the Protein Society. 14: 2982-92. PMID 16260760 DOI: 10.1110/Ps.051687305  1
2005 Heidary DK, Roy M, Daumy GO, Cong Y, Jennings PA. Long-range coupling between separate docking sites in interleukin-1beta. Journal of Molecular Biology. 353: 1187-98. PMID 16216268 DOI: 10.1016/J.Jmb.2005.08.072  1
2005 Lieser SA, Aubol BE, Wong L, Jennings PA, Adams JA. Coupling phosphoryl transfer and substrate interactions in protein kinases. Biochimica Et Biophysica Acta. 1754: 191-9. PMID 16213199 DOI: 10.1016/J.Bbapap.2005.07.024  1
2005 Wong L, Lieser SA, Miyashita O, Miller M, Tasken K, Onuchic JN, Adams JA, Woods VL, Jennings PA. Coupled motions in the SH2 and kinase domains of Csk control Src phosphorylation. Journal of Molecular Biology. 351: 131-43. PMID 16002086 DOI: 10.1016/J.Jmb.2005.05.042  1
2005 Wriggers W, Chakravarty S, Jennings PA. Control of protein functional dynamics by peptide linkers. Biopolymers. 80: 736-46. PMID 15880774 DOI: 10.1002/Bip.20291  1
2005 Roy M, Chavez LL, Finke JM, Heidary DK, Onuchic JN, Jennings PA. The native energy landscape for interleukin-1beta. Modulation of the population ensemble through native-state topology. Journal of Molecular Biology. 348: 335-47. PMID 15811372 DOI: 10.1016/J.Jmb.2005.02.059  1
2005 Covalt JC, Cao TB, Magdaroag JR, Gross LA, Jennings PA. Temperature, media, and point of induction affect the N-terminal processing of interleukin-1beta. Protein Expression and Purification. 41: 45-52. PMID 15802220 DOI: 10.1016/J.Pep.2005.01.010  1
2004 Jiang T, Olson ES, Nguyen QT, Roy M, Jennings PA, Tsien RY. Tumor imaging by means of proteolytic activation of cell-penetrating peptides. Proceedings of the National Academy of Sciences of the United States of America. 101: 17867-72. PMID 15601762 DOI: 10.1073/Pnas.0408191101  1
2004 Rodríguez JC, Jennings PA, Melacini G. Using chemical exchange to assign non-covalent protein complexes in slow exchange with the free state: enhanced resolution and efficient signal editing. Journal of Biomolecular Nmr. 30: 155-61. PMID 15557802 DOI: 10.1023/B:Jnmr.0000048857.44219.C3  1
2004 Wong L, Lieser S, Chie-Leon B, Miyashita O, Aubol B, Shaffer J, Onuchic JN, Jennings PA, Woods VL, Adams JA. Dynamic coupling between the SH2 domain and active site of the COOH terminal Src kinase, Csk. Journal of Molecular Biology. 341: 93-106. PMID 15312765 DOI: 10.1016/J.Jmb.2004.05.060  1
2004 Plesniak LA, Parducho JI, Ziebart A, Geierstanger BH, Whiles JA, Melacini G, Jennings PA. Orientation and helical conformation of a tissue-specific hunter-killer peptide in micelles. Protein Science : a Publication of the Protein Society. 13: 1988-96. PMID 15273301 DOI: 10.1110/Ps.04853204  1
2004 Wong L, Jennings PA, Adams JA. Communication pathways between the nucleotide pocket and distal regulatory sites in protein kinases. Accounts of Chemical Research. 37: 304-11. PMID 15147171 DOI: 10.1021/Ar020128G  1
2003 Morikis D, Elcock AH, Jennings PA, McCammon JA. The pH dependence of stability of the activation helix and the catalytic site of GART. Biophysical Chemistry. 105: 279-91. PMID 14499900 DOI: 10.1016/S0301-4622(03)00079-6  1
2003 Banky P, Roy M, Newlon MG, Morikis D, Haste NM, Taylor SS, Jennings PA. Related protein-protein interaction modules present drastically different surface topographies despite a conserved helical platform. Journal of Molecular Biology. 330: 1117-29. PMID 12860132 DOI: 10.1016/S0022-2836(03)00552-7  1
2003 Roy M, Jennings PA. Real-time NMR kinetic studies provide global and residue-specific information on the non-cooperative unfolding of the beta-trefoil protein, interleukin-1beta. Journal of Molecular Biology. 328: 693-703. PMID 12706726 DOI: 10.1016/S0022-2836(03)00340-1  1
2003 Rodríguez JC, Wong L, Jennings PA. The solvent in CNBr cleavage reactions determines the fragmentation efficiency of ketosteroid isomerase fusion proteins used in the production of recombinant peptides. Protein Expression and Purification. 28: 224-31. PMID 12699685 DOI: 10.1016/S1046-5928(02)00700-3  1
2003 Alto NM, Soderling SH, Hoshi N, Langeberg LK, Fayos R, Jennings PA, Scott JD. Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring. Proceedings of the National Academy of Sciences of the United States of America. 100: 4445-50. PMID 12672969 DOI: 10.1073/Pnas.0330734100  1
2003 Fayos R, Melacini G, Newlon MG, Burns L, Scott JD, Jennings PA. Induction of flexibility through protein-protein interactions. The Journal of Biological Chemistry. 278: 18581-7. PMID 12604595 DOI: 10.1074/Jbc.M300866200  1
2003 Rudolph MG, Kelker MS, Schneider TR, Yeates TO, Oseroff V, Heidary DK, Jennings PA, Wilson IA. Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta. Acta Crystallographica. Section D, Biological Crystallography. 59: 290-8. PMID 12554939 DOI: 10.1107/S0907444902021704  1
2002 Finke JM, Jennings PA. Interleukin-1 beta folding between pH 5 and 7: experimental evidence for three-state folding behavior and robust transition state positions late in folding. Biochemistry. 41: 15056-67. PMID 12475255 DOI: 10.1021/Bi026197K  1
2002 Plesniak L, Horiuchi Y, Sem D, Meinenger D, Stiles L, Shaffer J, Jennings PA, Adams JA. Probing the nucleotide binding domain of the osmoregulator EnvZ using fluorescent nucleotide derivatives. Biochemistry. 41: 13876-82. PMID 12437344 DOI: 10.1021/Bi020331J  1
2002 Hamuro Y, Wong L, Shaffer J, Kim JS, Stranz DD, Jennings PA, Woods VL, Adams JA. Phosphorylation driven motions in the COOH-terminal Src kinase, CSK, revealed through enhanced hydrogen-deuterium exchange and mass spectrometry (DXMS). Journal of Molecular Biology. 323: 871-81. PMID 12417200 DOI: 10.1016/S0022-2836(02)01003-3  1
2002 Rodríguez JC, Jennings PA, Melacini G. Effect of chemical exchange on radiation damping in aqueous solutions of the osmolyte glycine Journal of the American Chemical Society. 124: 6240-6241. PMID 12033843 DOI: 10.1021/Ja0256966  1
2002 Morikis D, Roy M, Newlon MG, Scott JD, Jennings PA. Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIalpha. European Journal of Biochemistry / Febs. 269: 2040-51. PMID 11985580 DOI: 10.1046/J.1432-1033.2002.02852.X  1
2002 Heidary DK, Jennings PA. Three topologically equivalent core residues affect the transition state ensemble in a protein folding reaction. Journal of Molecular Biology. 316: 789-98. PMID 11866531 DOI: 10.1006/Jmbi.2001.5270  1
2002 Morikis D, Roy M, Sahu A, Troganis A, Jennings PA, Tsokos GC, Lambris JD. The structural basis of compstatin activity examined by structure-function-based design of peptide analogs and NMR. The Journal of Biological Chemistry. 277: 14942-53. PMID 11847226 DOI: 10.1074/Jbc.M200021200  1
2001 Finke JM, Jennings PA. Early aggregated States in the folding of interleukin-1β. Journal of Biological Physics. 27: 119-31. PMID 23345738 DOI: 10.1023/A:1013178505077  1
2001 Morikis D, Elcock AH, Jennings PA, McCammon JA. Proton transfer dynamics of GART: the pH-dependent catalytic mechanism examined by electrostatic calculations. Protein Science : a Publication of the Protein Society. 10: 2379-92. PMID 11604543 DOI: 10.1110/Ps.17301  1
2001 Morikis D, Elcock AH, Jennings PA, McCammon JA. Native-state conformational dynamics of GART: a regulatory pH-dependent coil-helix transition examined by electrostatic calculations. Protein Science : a Publication of the Protein Society. 10: 2363-78. PMID 11604542 DOI: 10.1110/Ps.17201  1
2001 Clementi C, Jennings PA, Onuchic JN. Prediction of folding mechanism for circular-permuted proteins. Journal of Molecular Biology. 311: 879-90. PMID 11518537 DOI: 10.1006/Jmbi.2001.4871  1
2001 Newlon MG, Roy M, Morikis D, Carr DW, Westphal R, Scott JD, Jennings PA. A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes. The Embo Journal. 20: 1651-62. PMID 11285229 DOI: 10.1093/Emboj/20.7.1651  1
2001 Andersen MD, Shaffer J, Jennings PA, Adams JA. Structural characterization of protein kinase A as a function of nucleotide binding. Hydrogen-deuterium exchange studies using matrix-assisted laser desorption ionization-time of flight mass spectrometry detection. The Journal of Biological Chemistry. 276: 14204-11. PMID 11278927 DOI: 10.1074/Jbc.M011543200  1
2001 Covalt JC, Roy M, Jennings PA. Core and surface mutations affect folding kinetics, stability and cooperativity in IL-1 beta: does alteration in buried water play a role? Journal of Molecular Biology. 307: 657-69. PMID 11254388 DOI: 10.1006/Jmbi.2001.4482  1
2000 Finke JM, Gross LA, Ho HM, Sept D, Zimm BH, Jennings PA. Commitment to folded and aggregated states occurs late in interleukin-1 beta folding. Biochemistry. 39: 15633-42. PMID 11112552 DOI: 10.1021/Bi001307D  1
2000 Banky P, Newlon MG, Roy M, Garrod S, Taylor SS, Jennings PA. Isoform-specific differences between the type Iα and IIα cyclic AMP-dependent protein kinase anchoring domains revealed by solution NMR Journal of Biological Chemistry. 275: 35146-35152. PMID 10899163 DOI: 10.1074/Jbc.M003961200  1
2000 Clementi C, Jennings PA, Onuchic JN. How native-state topology affects the folding of dihydrofolate reductase and interleukin-1beta. Proceedings of the National Academy of Sciences of the United States of America. 97: 5871-6. PMID 10811910 DOI: 10.1073/Pnas.100547897  1
2000 Heidary DK, O'Neill JC, Roy M, Jennings PA. An essential intermediate in the folding of dihydrofolate reductase. Proceedings of the National Academy of Sciences of the United States of America. 97: 5866-70. PMID 10811909 DOI: 10.1073/Pnas.100547697  1
2000 Finke JM, Roy M, Zimm BH, Jennings PA. Aggregation events occur prior to stable intermediate formation during refolding of interleukin 1beta. Biochemistry. 39: 575-83. PMID 10642182 DOI: 10.1021/Bi991518M  1
1999 Newlon MG, Roy M, Morikis D, Hausken ZE, Coghlan V, Scott JD, Jennings PA. The molecular basis for protein kinase A anchoring revealed by solution NMR. Nature Structural Biology. 6: 222-7. PMID 10074940 DOI: 10.1038/6663  1
1998 Jennings PA. Speeding along the protein folding highway, are we reading the signs correctly? Nature Structural Biology. 5: 846-8. PMID 9783738 DOI: 10.1038/2286  1
1998 Su Y, Yamashita MM, Greasley SE, Mullen CA, Shim JH, Jennings PA, Benkovic SJ, Wilson IA. A pH-dependent stabilization of an active site loop observed from low and high pH crystal structures of mutant monomeric glycinamide ribonucleotide transformylase at 1.8 to 1.9 A. Journal of Molecular Biology. 281: 485-99. PMID 9698564 DOI: 10.1006/Jmbi.1998.1931  1
1998 Mullen CA, Jennings PA. A single mutation disrupts the pH-dependent dimerization of glycinamide ribonucleotide transformylase. Journal of Molecular Biology. 276: 819-27. PMID 9500916 DOI: 10.1006/Jmbi.1997.1530  1
1998 Jennings PA. Title- 3D structural analysis of kinase anchoring interactions Faseb Journal. 12: A1297.  1
1998 Newlon MG, Roy M, Hausken ZE, Scott JD, Jennings PA. The solution structure of the A-kinase anchoring domain of type Ha cAMP-dependent protein kinase Faseb Journal. 12: A1449.  1
1997 Eliezer D, Jennings PA, Dyson HJ, Wright PE. Populating the equilibrium molten globule state of apomyoglobin under conditions suitable for structural characterization by NMR. Febs Letters. 417: 92-6. PMID 9395082 DOI: 10.1016/S0014-5793(97)01256-8  1
1997 Heidary DK, Gross LA, Roy M, Jennings PA. Evidence for an obligatory intermediate in the folding of interleukin-1 beta. Nature Structural Biology. 4: 725-31. PMID 9303000 DOI: 10.1038/Nsb0997-725  1
1997 Newlon MG, Roy M, Hausken ZE, Scott JD, Jennings PA. The A-kinase anchoring domain of type IIalpha cAMP-dependent protein kinase is highly helical. The Journal of Biological Chemistry. 272: 23637-44. PMID 9295304 DOI: 10.1074/Jbc.272.38.23637  1
1997 Sánchez M, Jennings PA, Murre C. Conformational changes induced in Hoxb-8/Pbx-1 heterodimers in solution and upon interaction with specific DNA. Molecular and Cellular Biology. 17: 5369-76. PMID 9271414 DOI: 10.1128/Mcb.17.9.5369  1
1996 Mullen CA, Jennings PA. Glycinamide ribonucleotide transformylase undergoes pH-dependent dimerization. Journal of Molecular Biology. 262: 746-55. PMID 8876651 DOI: 10.1006/Jmbi.1996.0549  1
1996 Massari ME, Jennings PA, Murre C. The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells. Molecular and Cellular Biology. 16: 121-9. PMID 8524288 DOI: 10.1128/Mcb.16.1.121  1
1995 Jennings PA, Stone MJ, Wright PE. Overexpression of myoglobin and assignment of its amide, C alpha and C beta resonances. Journal of Biomolecular Nmr. 6: 271-6. PMID 8520219 DOI: 10.1007/Bf00197808  1
1995 Gerendasy DD, Herron SR, Jennings PA, Sutcliffe JG. Calmodulin stabilizes an amphiphilic alpha-helix within RC3/neurogranin and GAP-43/neuromodulin only when Ca2+ is absent. The Journal of Biological Chemistry. 270: 6741-50. PMID 7896819 DOI: 10.1074/Jbc.270.12.6741  1
1995 Eliezer D, Jennings PA, Wright PE, Doniach S, Hodgson KO, Tsuruta H. The radius of gyration of an apomyoglobin folding intermediate. Science (New York, N.Y.). 270: 487-8. PMID 7570004 DOI: 10.1126/Science.270.5235.487  1
1994 Jones BE, Jennings PA, Pierre RA, Matthews CR. Development of nonpolar surfaces in the folding of Escherichia coli dihydrofolate reductase detected by 1-anilinonaphthalene-8-sulfonate binding. Biochemistry. 33: 15250-8. PMID 7803387  0.96
1993 Jennings PA, Finn BE, Jones BE, Matthews CR. A reexamination of the folding mechanism of dihydrofolate reductase from Escherichia coli: verification and refinement of a four-channel model. Biochemistry. 32: 3783-9. PMID 8466916  1
1993 Jennings PA, Wright PE. Formation of a molten globule intermediate early in the kinetic folding pathway of apomyoglobin. Science (New York, N.Y.). 262: 892-6. PMID 8235610 DOI: 10.1126/Science.8235610  1
1991 Jennings PA, Saalau-Bethell SM, Finn BE, Chen XW, Matthews CR. Mutational analysis of protein folding mechanisms. Methods in Enzymology. 202: 113-26. PMID 1784172 DOI: 10.1016/0076-6879(91)02009-X  1
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