Year |
Citation |
Score |
2020 |
Sheetz JB, Mathea S, Karvonen H, Malhotra K, Chatterjee D, Niininen W, Perttilä R, Preuss F, Suresh K, Stayrook SE, Tsutsui Y, Radhakrishnan R, Ungureanu D, Knapp S, Lemmon MA. Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases. Molecular Cell. PMID 32619402 DOI: 10.1016/J.Molcel.2020.06.018 |
0.402 |
|
2020 |
Bradley RP, Slochower DR, Janmey PA, Radhakrishnan R. Divalent cations bind to phosphoinositides to induce ion and isomer specific propensities for nano-cluster initiation in bilayer membranes. Royal Society Open Science. 7: 192208. PMID 32537210 DOI: 10.1098/Rsos.192208 |
0.355 |
|
2020 |
Fatunmbi O, Bradley RP, Kandy SK, Bucki R, Janmey PA, Radhakrishnan R. A multiscale biophysical model for the recruitment of actin nucleating proteins at the membrane interface. Soft Matter. PMID 32436537 DOI: 10.1039/D0Sm00267D |
0.364 |
|
2020 |
da Silva FLB, Carloni P, Cheung D, Cottone G, Donnini S, Allen Foegeding E, Gulzar M, Jacquier JC, Lobaskin V, MacKernan D, Naveh ZMH, Radhakrishnan R, Santiso EE. Understanding and Controlling Food Protein Structure and Function in Foods: Perspectives from Experiments and Computer Simulations. Annual Review of Food Science and Technology. PMID 31951485 DOI: 10.1146/Annurev-Food-032519-051640 |
0.635 |
|
2020 |
Mao L, Zhan YY, Wu B, Yu Q, Xu L, Hong X, Zhong L, Mi P, Xiao L, Wang X, Cao H, Zhang W, Chen B, Xiang J, Mei K, ... Radhakrishnan R, et al. ULK1 phosphorylates Exo70 to suppress breast cancer metastasis. Nature Communications. 11: 117. PMID 31913283 DOI: 10.1038/S41467-019-13923-7 |
0.309 |
|
2019 |
Farokhirad S, Bradley RP, Radhakrishnan R. Thermodynamic analysis of multivalent binding of functionalized nanoparticles to membrane surface reveals the importance of membrane entropy and nanoparticle entropy in adhesion of flexible nanoparticles. Soft Matter. PMID 31670338 DOI: 10.1039/C9Sm01653H |
0.328 |
|
2019 |
Kandy SK, Radhakrishnan R. Emergent membrane morphologies in relaxed and tense membranes in presence of reversible adhesive pinning interactions. Physical Biology. PMID 31561242 DOI: 10.1088/1478-3975/Ab48D5 |
0.306 |
|
2019 |
Ghosh A, Radhakrishnan R. Time-dependent antagonist-agonist switching in receptor tyrosine kinase-mediated signaling. Bmc Bioinformatics. 20: 242. PMID 31092187 DOI: 10.1186/S12859-019-2816-3 |
0.388 |
|
2019 |
Jordan EJ, Patil K, Suresh K, Park JH, Mosse YP, Lemmon MA, Radhakrishnan R. Computational algorithms for in silico profiling of activating mutations in cancer. Cellular and Molecular Life Sciences : Cmls. PMID 30982079 DOI: 10.1007/S00018-019-03097-2 |
0.356 |
|
2019 |
Bucki R, Wang YH, Yang C, Kandy SK, Fatunmbi O, Bradley R, Pogoda K, Svitkina T, Radhakrishnan R, Janmey PA. Lateral distribution of phosphatidylinositol 4,5-bisphosphate in membranes regulates formin and ARP2/3 -mediated actin nucleation. The Journal of Biological Chemistry. PMID 30692198 DOI: 10.1074/Jbc.Ra118.005552 |
0.32 |
|
2019 |
Kai F, Ou G, Long A, Guo W, Tourdot R, Radhakrishnan R, Chen C, Dumont S, Weaver VM. Abstract 1028: Extracellular matrix dimensionality reduces cellular cortical tension to stimulate pro-survival signaling in mammary epithelial cells Cancer Research. 79: 1028-1028. DOI: 10.1158/1538-7445.Am2019-1028 |
0.315 |
|
2019 |
Fatunmbi O, Bradley R, Bucki R, Janmey P, Radhakrishnan R. Recruitment of Actin-Binding Proteins on the Membrane Interface: Effects of Cholesterol on Protein/PIP2 Interactions Biophysical Journal. 116: 40a-41a. DOI: 10.1016/J.Bpj.2018.11.263 |
0.302 |
|
2018 |
Janmey PA, Bucki R, Radhakrishnan R. Regulation of actin assembly by PI(4,5)P2 and other inositol phospholipids: An update on possible mechanisms. Biochemical and Biophysical Research Communications. PMID 30139519 DOI: 10.1016/J.Bbrc.2018.07.155 |
0.319 |
|
2018 |
Ramakrishnan N, Bradley RP, Tourdot RW, Radhakrishnan R. Biophysics of membrane curvature remodeling at molecular and mesoscopic lengthscales. Journal of Physics. Condensed Matter : An Institute of Physics Journal. PMID 29786613 DOI: 10.1088/1361-648X/Aac702 |
0.364 |
|
2018 |
McKenzie M, Ha SM, Rammohan A, Radhakrishnan R, Ramakrishnan N. Multivalent Binding of a Ligand-Coated Particle: Role of Shape, Size, and Ligand Heterogeneity. Biophysical Journal. 114: 1830-1846. PMID 29694862 DOI: 10.1016/J.Bpj.2018.03.007 |
0.318 |
|
2017 |
Natesan R, Sreeja KK, Roychoudhuri A, Eckmann DM, Ayyaswamy PS, Baumgart T, Pucadyil T, Patil SV, Weaver VM, Radhakrishnan R. Excess area dependent scaling behavior of nano-sized membrane tethers. Physical Biology. PMID 29116056 DOI: 10.1088/1478-3975/Aa9905 |
0.317 |
|
2017 |
Radhakrishnan R, Yu HY, Eckmann DM, Ayyaswamy PS. Computational Models for Nanoscale Fluid Dynamics and Transport Inspired by Nonequilibrium Thermodynamics. Journal of Heat Transfer. 139: 0330011-330019. PMID 28035168 DOI: 10.1115/1.4035006 |
0.307 |
|
2017 |
Rammohan AR, Mckenzie M, Radhakrishnan R, Ramakrishnan N. A Computational Framework to Accurately Predict Enthalpy and Configurational Entropy Landscapes of Multivalent Interactions of Cell Mimetics Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.2316 |
0.373 |
|
2017 |
Jordan EJ, Radhakrishnan R. We Can Predict the Effects of Kinase Domain Mutations using Molecular Dynamics and Machine Learning Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.1747 |
0.412 |
|
2016 |
Li N, Sharifi-Mood N, Tu F, Lee D, Radhakrishnan R, Baumgart T, Stebe KJ. Curvature-Driven Migration of Colloids on Tense Lipid Bilayers. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 28036186 DOI: 10.1021/Acs.Langmuir.6B03406 |
0.314 |
|
2016 |
Ramakrishnan N, Tourdot RW, Radhakrishnan R. Thermodynamic free energy methods to investigate shape transitions in bilayer membranes. International Journal of Advances in Engineering Sciences and Applied Mathematics. 8: 88-100. PMID 27616867 DOI: 10.1007/S12572-015-0159-5 |
0.364 |
|
2016 |
Bradley RP, Radhakrishnan R. Curvature-undulation coupling as a basis for curvature sensing and generation in bilayer membranes. Proceedings of the National Academy of Sciences of the United States of America. PMID 27531962 DOI: 10.1073/Pnas.1605259113 |
0.335 |
|
2016 |
Ramakrishnan N, Tourdot RW, Eckmann DM, Ayyaswamy PS, Muzykantov VR, Radhakrishnan R. Biophysically inspired model for functionalized nanocarrier adhesion to cell surface: roles of protein expression and mechanical factors. Royal Society Open Science. 3: 160260. PMID 27429783 DOI: 10.1098/Rsos.160260 |
0.366 |
|
2016 |
Freed DM, Park JH, Radhakrishnan R, Lemmon MA. Deletion Mutations Keep Kinase Inhibitors in the Loop. Cancer Cell. 29: 423-5. PMID 27070691 DOI: 10.1016/J.Ccell.2016.03.017 |
0.338 |
|
2016 |
Rammohan AR, Mckenzie M, Radhakrishnan R, Ramakrishnan N. Cellular Adhesion: Evaluating the Effect of Receptor-Ligand Chemistries, Distribution of Receptors, and Spread Versus Spherical Cell Geometry Biophysical Journal. 110: 623a. DOI: 10.1016/J.Bpj.2015.11.3343 |
0.381 |
|
2015 |
Ramakrishnan N, Radhakrishnan R. Phenomenology based multiscale models as tools to understand cell membrane and organelle morphologies. Advances in Planar Lipid Bilayers and Liposomes. 22: 129-175. PMID 27087801 DOI: 10.1016/Bs.Adplan.2015.06.004 |
0.366 |
|
2015 |
Tourdot RW, Ramakrishnan N, Baumgart T, Radhakrishnan R. Application of a free-energy-landscape approach to study tension-dependent bilayer tubulation mediated by curvature-inducing proteins. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 92: 042715. PMID 26565280 DOI: 10.1103/Physreve.92.042715 |
0.354 |
|
2015 |
Sarkar A, Eckmann DM, Ayyaswamy PS, Radhakrishnan R. Hydrodynamic interactions of deformable polymeric nanocarriers and the effect of crosslinking. Soft Matter. 11: 5955-69. PMID 26126781 DOI: 10.1039/C5Sm00669D |
0.31 |
|
2015 |
Slochower DR, Wang YH, Radhakrishnan R, Janmey PA. Physical chemistry and membrane properties of two phosphatidylinositol bisphosphate isomers. Physical Chemistry Chemical Physics : Pccp. 17: 12608-15. PMID 25901568 DOI: 10.1039/C5Cp00862J |
0.301 |
|
2015 |
Rammohan AR, Mckenzie M, Miner J, ramakrishnan N, Radhakrishnan R. A Self-Consistent Multiscale Methodology for Predicting Adhesion of Mammalian Cells onto Functionalized Surfaces Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.3442 |
0.301 |
|
2015 |
Jordan EJ, Huwe PJ, Mosse Y, Lemmon M, Radhakrishnan R. Predicting the Effects of Clinically Observed Kinase Mutations using Molecular Modeling and Machine Learning Algorithms Biophysical Journal. 108: 376a. DOI: 10.1016/J.Bpj.2014.11.2063 |
0.409 |
|
2014 |
Bresler SC, Weiser DA, Huwe PJ, Park JH, Krytska K, Ryles H, Laudenslager M, Rappaport EF, Wood AC, McGrady PW, Hogarty MD, London WB, Radhakrishnan R, Lemmon MA, Mossé YP. ALK mutations confer differential oncogenic activation and sensitivity to ALK inhibition therapy in neuroblastoma. Cancer Cell. 26: 682-94. PMID 25517749 DOI: 10.1016/J.Ccell.2014.09.019 |
0.354 |
|
2014 |
Ramakrishnan N, Sunil Kumar PB, Radhakrishnan R. Mesoscale computational studies of membrane bilayer remodeling by curvature-inducing proteins. Physics Reports. 543: 1-60. PMID 25484487 DOI: 10.1016/J.Physrep.2014.05.001 |
0.383 |
|
2014 |
Tourdot RW, Bradley RP, Ramakrishnan N, Radhakrishnan R. Multiscale computational models in physical systems biology of intracellular trafficking. Iet Systems Biology. 8: 198-213. PMID 25257021 DOI: 10.1049/Iet-Syb.2013.0057 |
0.388 |
|
2014 |
Tourdot RW, Ramakrishnan N, Radhakrishnan R. Defining the free-energy landscape of curvature-inducing proteins on membrane bilayers. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 90: 022717. PMID 25215768 DOI: 10.1103/Physreve.90.022717 |
0.346 |
|
2014 |
Gajula KS, Huwe PJ, Mo CY, Crawford DJ, Stivers JT, Radhakrishnan R, Kohli RM. High-throughput mutagenesis reveals functional determinants for DNA targeting by activation-induced deaminase. Nucleic Acids Research. 42: 9964-75. PMID 25064858 DOI: 10.1093/Nar/Gku689 |
0.32 |
|
2014 |
Liu J, Ayyaswamy PS, Eckmann DM, Radhakrishnan R. Modelling of Binding Free Energy of Targeted Nanocarriers to Cell Surface. Heat and Mass Transfer = Warme- Und Stoffubertragung. 50: 315-321. PMID 25013307 DOI: 10.1007/S00231-013-1274-0 |
0.336 |
|
2014 |
Liu Y, Radhakrishnan R. Computational delineation of tyrosyl-substrate recognition and catalytic landscapes by the epidermal growth factor receptor tyrosine kinase domain. Molecular Biosystems. 10: 1890-904. PMID 24779031 DOI: 10.1039/C3Mb70620F |
0.734 |
|
2014 |
Raghavan S, Joshi S, Dawson-Eli A, Rammohan AR, McKenzie ME, Natesan R, Radhakrishnan R. Cell Adhesion Sensitivity to Cell Size and Surface Receptor Densities Biophysical Journal. 106: 809a. DOI: 10.1016/J.Bpj.2013.11.4434 |
0.309 |
|
2014 |
Ramakrishnan N, Bradley RP, Tourdot R, Radhakrishnan R. Cellular Scale Biophysical Models of Membrane Sculpting by the Proteins During Endocytosis and Exocytosis Biophysical Journal. 106: 310a. DOI: 10.1016/J.Bpj.2013.11.1798 |
0.374 |
|
2013 |
Bradley R, Radhakrishnan R. Coarse-Grained Models for Protein-Cell Membrane Interactions. Polymers. 5: 890-936. PMID 26613047 DOI: 10.3390/Polym5030890 |
0.362 |
|
2013 |
Telesco SE, Vadigepalli R, Radhakrishnan R. Molecular modeling of ErbB4/HER4 kinase in the context of the HER4 signaling network helps rationalize the effects of clinically identified HER4 somatic mutations on the cell phenotype. Biotechnology Journal. 8: 1452-64. PMID 24318637 DOI: 10.1002/Biot.201300022 |
0.747 |
|
2013 |
Zhao Y, Liu J, Yang C, Capraro BR, Baumgart T, Bradley RP, Ramakrishnan N, Xu X, Radhakrishnan R, Svitkina T, Guo W. Exo70 generates membrane curvature for morphogenesis and cell migration. Developmental Cell. 26: 266-78. PMID 23948253 DOI: 10.1016/J.Devcel.2013.07.007 |
0.326 |
|
2013 |
Ayyaswamy PS, Muzykantov V, Eckmann DM, Radhakrishnan R. Nanocarrier Hydrodynamics and Binding in Targeted Drug Delivery: Challenges in Numerical Modeling and Experimental Validation. Journal of Nanotechnology in Engineering and Medicine. 4: 101011-1010115. PMID 23917383 DOI: 10.1115/1.4024004 |
0.335 |
|
2013 |
Radhakrishnan R, Uma B, Liu J, Ayyaswamy PS, Eckmann DM. Temporal Multiscale Approach for Nanocarrier Motion with Simultaneous Adhesion and Hydrodynamic Interactions in Targeted Drug Delivery. Journal of Computational Physics. 244: 252-263. PMID 23853388 DOI: 10.1016/J.Jcp.2012.10.026 |
0.322 |
|
2013 |
Slochower DR, Huwe PJ, Radhakrishnan R, Janmey PA. Quantum and all-atom molecular dynamics simulations of protonation and divalent ion binding to phosphatidylinositol 4,5-bisphosphate (PIP2). The Journal of Physical Chemistry. B. 117: 8322-9. PMID 23786273 DOI: 10.1021/Jp401414Y |
0.342 |
|
2013 |
Liu Y, Agrawal NJ, Radhakrishnan R. A flexible-protein molecular docking study of the binding of ruthenium complex compounds to PIM1, GSK-3β, and CDK2/Cyclin A protein kinases. Journal of Molecular Modeling. 19: 371-82. PMID 22926267 DOI: 10.1007/S00894-012-1555-4 |
0.776 |
|
2013 |
Bradley R, Ramakrishnan N, Zhao Y, Guo W, Radhakrishnan R. Membrane Remodeling by Curvature-Inducing Proteins Biophysical Journal. 104: 98a. DOI: 10.1016/J.Bpj.2012.11.581 |
0.377 |
|
2013 |
Huwe PJ, Bresler S, Park J, Lemmon M, Radhakrishnan R. Understanding Kinase Activation of ALK in Neuroblastoma Patients Biophysical Journal. 104: 662a. DOI: 10.1016/J.Bpj.2012.11.3654 |
0.424 |
|
2013 |
Jordan J, Jin S, Hua X, Radhakrishnan R. Computational Studies of Binding of Small Molecule Inhibitors to the DNA Binding Protein Menin Biophysical Journal. 104: 57a-58a. DOI: 10.1016/J.Bpj.2012.11.357 |
0.361 |
|
2013 |
Tourdot RW, Natesan R, Radhakrishnan R. Mesoscale Simulations of Curvature Inducing Proteins on Wavy Membranes Biophysical Journal. 104: 244a. DOI: 10.1016/J.Bpj.2012.11.1375 |
0.335 |
|
2013 |
Natesan R, Tourdot RW, Radhakrishnan R. Membrane Remodelling and Protein Interactions - A Free Energy Perspective Biophysical Journal. 104: 243a. DOI: 10.1016/J.Bpj.2012.11.1371 |
0.356 |
|
2012 |
Uma B, Radhakrishnan R, Eckmann DM, Ayyaswamy PS. Nanocarrier-Cell Surface Adhesive and Hydrodynamic Interactions: Ligand-Receptor Bond Sensitivity Study. Journal of Nanotechnology in Engineering and Medicine. 3: 310101-310108. PMID 23917171 DOI: 10.1115/1.4007522 |
0.352 |
|
2012 |
Park JH, Liu Y, Lemmon MA, Radhakrishnan R. Erlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domain. The Biochemical Journal. 448: 417-23. PMID 23101586 DOI: 10.1042/Bj20121513 |
0.721 |
|
2012 |
Telesco SE, Radhakrishnan R. Structural systems biology and multiscale signaling models. Annals of Biomedical Engineering. 40: 2295-306. PMID 22539148 DOI: 10.1007/S10439-012-0576-6 |
0.707 |
|
2012 |
Liu J, Agrawal NJ, Eckmann DM, Ayyaswamy PS, Radhakrishnan R. Top-down mesoscale models and free energy calculations of multivalent protein-protein and protein-membrane interactions in nanocarrier adhesion and receptor trafficking Rsc Biomolecular Sciences. 1: 272-292. |
0.63 |
|
2011 |
Telesco SE, Shih A, Liu Y, Radhakrishnan R. Investigating Molecular Mechanisms of Activation and Mutation of the HER2 Receptor Tyrosine Kinase through Computational Modeling and Simulation. Cancer Research Journal. 4: 1-35. PMID 25346782 |
0.796 |
|
2011 |
Purvis JE, Shih AJ, Liu Y, Radhakrishnan R. Cancer Cell: Linking Oncogenic Signaling to Molecular Structure. Chapman & Hall/Crc Mathematical & Computational Biology Series. 2011: 31-44. PMID 25285322 |
0.768 |
|
2011 |
Liu J, Bradley R, Eckmann DM, Ayyaswamy PS, Radhakrishnan R. Multiscale Modeling of Functionalized Nanocarriers in Targeted Drug Delivery. Current Nanoscience. 7: 727-735. PMID 22116782 DOI: 10.2174/157341311797483826 |
0.369 |
|
2011 |
Ramanan V, Agrawal NJ, Liu J, Engles S, Toy R, Radhakrishnan R. Systems biology and physical biology of clathrin-mediated endocytosis. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 803-15. PMID 21792431 DOI: 10.1039/C1Ib00036E |
0.669 |
|
2011 |
Liu J, Agrawal NJ, Calderon A, Ayyaswamy PS, Eckmann DM, Radhakrishnan R. Multivalent binding of nanocarrier to endothelial cells under shear flow. Biophysical Journal. 101: 319-26. PMID 21767483 DOI: 10.1016/J.Bpj.2011.05.063 |
0.648 |
|
2011 |
Shih AJ, Telesco SE, Radhakrishnan R. Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases. Cancers. 3: 1195-231. PMID 21701703 DOI: 10.3390/Cancers3011195 |
0.796 |
|
2011 |
Telesco SE, Shih AJ, Jia F, Radhakrishnan R. A multiscale modeling approach to investigate molecular mechanisms of pseudokinase activation and drug resistance in the HER3/ErbB3 receptor tyrosine kinase signaling network. Molecular Biosystems. 7: 2066-80. PMID 21509365 DOI: 10.1039/C0Mb00345J |
0.808 |
|
2011 |
Shih AJ, Telesco SE, Choi SH, Lemmon MA, Radhakrishnan R. Molecular dynamics analysis of conserved hydrophobic and hydrophilic bond-interaction networks in ErbB family kinases. The Biochemical Journal. 436: 241-51. PMID 21426301 DOI: 10.1042/Bj20101791 |
0.805 |
|
2011 |
Liu J, Zern B, Ayyaswamy P, Eckmann D, Muzykantov V, Radhakrishnan R. Monte Carlo Simulations of Absolute Binding Free Energy of Targeted Nanocarriers to Cell Surfaces Biophysical Journal. 100: 614a-615a. DOI: 10.1016/J.Bpj.2010.12.3539 |
0.336 |
|
2010 |
Agrawal NJ, Nukpezah J, Radhakrishnan R. Minimal mesoscale model for protein-mediated vesiculation in clathrin-dependent endocytosis. Plos Computational Biology. 6. PMID 20838575 DOI: 10.1371/Journal.Pcbi.1000926 |
0.658 |
|
2010 |
Liu J, Weller GE, Zern B, Ayyaswamy PS, Eckmann DM, Muzykantov VR, Radhakrishnan R. Computational model for nanocarrier binding to endothelium validated using in vivo, in vitro, and atomic force microscopy experiments. Proceedings of the National Academy of Sciences of the United States of America. 107: 16530-5. PMID 20823256 DOI: 10.1073/Pnas.1006611107 |
0.335 |
|
2010 |
Shi F, Telesco SE, Liu Y, Radhakrishnan R, Lemmon MA. ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 107: 7692-7. PMID 20351256 DOI: 10.1073/Pnas.1002753107 |
0.799 |
|
2010 |
Venkatramani R, Radhakrishnan R. Computational delineation of the catalytic step of a high-fidelity DNA polymerase. Protein Science : a Publication of the Protein Society. 19: 815-25. PMID 20162624 DOI: 10.1002/Pro.361 |
0.621 |
|
2010 |
Shih AJ, Telesco SE, Choi SH, Lemmon MA, Radhakrishnan R. Conserved Hydrophobic and Hydrophilic Bond Interaction Networks in ErbB Family Kinases Biophysical Journal. 98: 445a. DOI: 10.1016/J.Bpj.2009.12.2417 |
0.801 |
|
2010 |
Liu J, Agrawal NJ, Ayyaswamy PS, Eckmann DM, Radhakrishnan R. Simulations of Binding Free Energy of Targeted Nanocarriers to Cell Surfaces: the Effects of Antigen Flexural Rigidity, Glycocalyx Resistance, and Shear Flow Biophysical Journal. 98: 392a. DOI: 10.1016/J.Bpj.2009.12.2114 |
0.667 |
|
2009 |
Agrawal NJ, Radhakrishnan R. Calculation of free energies in fluid membranes subject to heterogeneous curvature fields. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 80: 011925. PMID 19658747 DOI: 10.1103/Physreve.80.011925 |
0.65 |
|
2009 |
Telesco SE, Radhakrishnan R. Atomistic insights into regulatory mechanisms of the HER2 tyrosine kinase domain: a molecular dynamics study. Biophysical Journal. 96: 2321-34. PMID 19289058 DOI: 10.1016/J.Bpj.2008.12.3912 |
0.755 |
|
2009 |
Suenaga A, Hatakeyama M, Kiyatkin AB, Radhakrishnan R, Taiji M, Kholodenko BN. Molecular dynamics simulations reveal that Tyr-317 phosphorylation reduces Shc binding affinity for phosphotyrosyl residues of epidermal growth factor receptor. Biophysical Journal. 96: 2278-88. PMID 19289054 DOI: 10.1016/J.Bpj.2008.11.018 |
0.45 |
|
2009 |
Agrawal NJ, Radhakrishnan R. Calculation of free energies in fluid membranes subject to heterogeneous curvature fields Physical Review E - Statistical, Nonlinear, and Soft Matter Physics. 80. DOI: 10.1103/PhysRevE.80.011925 |
0.622 |
|
2009 |
Radhakrishnan R, Agrawal NJ. Computational Delineation of the Bioenergetics of Protein-Mediated Orchestration of Membrane Vesiculation in Clathrin-Dependent Endocytosis Biophysical Journal. 96: 570a. DOI: 10.1016/J.Bpj.2008.12.3736 |
0.664 |
|
2008 |
Agrawal NJ, Weinstein J, Radhakrishnan R. Landscape of finite-temperature equilibrium behaviour of curvature-inducing proteins on a bilayer membrane explored using a linearized elastic free energy model. Molecular Physics. 106: 1913-1923. PMID 21243078 DOI: 10.1080/00268970802365990 |
0.663 |
|
2008 |
Shih AJ, Purvis J, Radhakrishnan R. Molecular systems biology of ErbB1 signaling: bridging the gap through multiscale modeling and high-performance computing. Molecular Biosystems. 4: 1151-9. PMID 19396377 DOI: 10.1039/B803806F |
0.685 |
|
2008 |
Purvis J, Ilango V, Radhakrishnan R. Role of network branching in eliciting differential short-term signaling responses in the hypersensitive epidermal growth factor receptor mutants implicated in lung cancer. Biotechnology Progress. 24: 540-53. PMID 18412405 DOI: 10.1021/Bp070405O |
0.403 |
|
2008 |
Venkatramani R, Radhakrishnan R. Computational study of the force dependence of phosphoryl transfer during DNA synthesis by a high fidelity polymerase. Physical Review Letters. 100: 088102. PMID 18352668 DOI: 10.1103/Physrevlett.100.088102 |
0.596 |
|
2008 |
Agrawal NJ, Radhakrishnan R, Purohit PK. Geometry of mediating protein affects the probability of loop formation in DNA. Biophysical Journal. 94: 3150-8. PMID 18192346 DOI: 10.1529/Biophysj.107.122986 |
0.644 |
|
2008 |
Venkatramani R, Radhakrishnan R. Effect of oxidatively damaged DNA on the active site preorganization during nucleotide incorporation in a high fidelity polymerase from Bacillus stearothermophilus. Proteins. 71: 1360-72. PMID 18058909 DOI: 10.1002/Prot.21824 |
0.607 |
|
2007 |
Agrawal NJ, Radhakrishnan R. The Role of Glycocalyx in Nanocarrier-Cell Adhesion Investigated Using a Thermodynamic Model and Monte Carlo Simulations. The Journal of Physical Chemistry. C, Nanomaterials and Interfaces. 111: 15848-15856. PMID 19081797 DOI: 10.1021/Jp074514X |
0.667 |
|
2007 |
Radhakrishnan R. Coupling of fast and slow modes in the reaction pathway of the minimal hammerhead ribozyme cleavage. Biophysical Journal. 93: 2391-9. PMID 17545240 DOI: 10.1529/Biophysj.107.104661 |
0.304 |
|
2007 |
Liu Y, Purvis J, Shih A, Weinstein J, Agrawal N, Radhakrishnan R. A multiscale computational approach to dissect early events in the Erb family receptor mediated activation, differential signaling, and relevance to oncogenic transformations. Annals of Biomedical Engineering. 35: 1012-25. PMID 17273938 DOI: 10.1007/S10439-006-9251-0 |
0.803 |
|
2006 |
Alba-Simionesco C, Coasne B, Dosseh G, Dudziak G, Gubbins KE, Radhakrishnan R, Sliwinska-Bartkowiak M. Effects of confinement on freezing and melting. Journal of Physics. Condensed Matter : An Institute of Physics Journal. 18: R15-68. PMID 21697556 DOI: 10.1088/0953-8984/18/6/R01 |
0.511 |
|
2006 |
Radhakrishnan R, Arora K, Wang Y, Beard WA, Wilson SH, Schlick T. Regulation of DNA repair fidelity by molecular checkpoints: "gates" in DNA polymerase beta's substrate selection. Biochemistry. 45: 15142-56. PMID 17176036 DOI: 10.1021/Bi061353Z |
0.333 |
|
2006 |
Radhakrishnan R, Schlick T. Correct and incorrect nucleotide incorporation pathways in DNA polymerase beta. Biochemical and Biophysical Research Communications. 350: 521-9. PMID 17022941 DOI: 10.1016/J.Bbrc.2006.09.059 |
0.345 |
|
2006 |
Radhakrishnan R. Mechanism of nucleotide incorporation in DNA polymerase beta. Biochemical and Biophysical Research Communications. 347: 626-33. PMID 16842743 DOI: 10.1016/J.Bbrc.2006.06.142 |
0.3 |
|
2006 |
Weinstein J, Radhakrishnan R. "KMC-TDGL" - A coarse-grained methodology for simulating interfacial dynamics in complex fluids: Application to protein-mediated membrane processes Molecular Physics. 104: 3653-3666. DOI: 10.1080/00268970600997580 |
0.34 |
|
2005 |
Hung FR, Gubbins KE, Radhakrishnan R, Szostak K, B́guin F, Dudziak G, Sliwinska-Bartkowiak M. Freezing/melting of Lennard-Jones fluids in carbon nanotubes Applied Physics Letters. 86: 1-3. DOI: 10.1063/1.1862786 |
0.684 |
|
2002 |
Radhakrishnan R, Gubbins KE, Sliwinska-Bartkowiak M. Existence of a hexatic phase in porous media. Physical Review Letters. 89: 076101. PMID 12190533 DOI: 10.1103/Physrevlett.89.076101 |
0.481 |
|
2002 |
Radhakrishnan R, Trout BL. A new approach for studying nucleation phenomena using molecular simulations: Application to CO2 hydrate clathrates Journal of Chemical Physics. 117: 1786-1796. DOI: 10.1063/1.1485962 |
0.313 |
|
2002 |
Radhakrishnan R, Gubbins KE, Sliwinska-Bartkowiak M. Global phase diagrams for freezing in porous media Journal of Chemical Physics. 116: 1147-1155. DOI: 10.1063/1.1426412 |
0.503 |
|
2002 |
Sliwinska-Bartkowiak M, Dudziak G, Radhakrishnan R, Gubbins KE. Freezing in Mesopores: Aniline in Silica Glasses and MCM-41 Studies in Surface Science and Catalysis. 144: 467-474. DOI: 10.1016/S0167-2991(02)80169-0 |
0.46 |
|
2001 |
Śliwinska-Bartkowiak M, Radhakrishnan R, Gubbins KE. Effect of confinement on melting in slit-shaped pores: Experimental and simulation study of aniline in activated carbon fibers Molecular Simulation. 27: 323-337. DOI: 10.1080/08927020108031356 |
0.47 |
|
2001 |
Sliwinska-Bartkowiak M, Dudziak G, Sikorski R, Gras R, Radhakrishnan R, Gubbins KE. Melting/freezing behavior of a fluid confined in porous glasses and MCM-41: Dielectric spectroscopy and molecular simulation Journal of Chemical Physics. 114: 950-962. DOI: 10.1063/1.1329343 |
0.524 |
|
2001 |
Sliwinska-Bartkowiak M, Dudziak G, Sikorski R, Gras R, Gubbins KE, Radhakrishnan R. Dielectric studies of freezing behavior in porous materials: Water and methanol in activated carbon fibres Physical Chemistry Chemical Physics. 3: 1179-1184. DOI: 10.1039/B009792F |
0.508 |
|
2001 |
Sliwinska-Bartkowiak M, Dudziak G, Gras R, Sikorski R, Radhakrishnan R, Gubbins KE. Freezing behavior in porous glasses and MCM-41 Colloids and Surfaces a: Physicochemical and Engineering Aspects. 187: 523-529. DOI: 10.1016/S0927-7757(01)00637-9 |
0.478 |
|
2000 |
Radhakrishnan R, Gubbins KE, Sliwinska-Bartkowiak M. Effect of the fluid-wall interaction on freezing of confined fluids: Toward the development of a global phase diagram Journal of Chemical Physics. 112: 11048-11057. DOI: 10.1063/1.481745 |
0.471 |
|
2000 |
Sliwinska–Bartkowiak M, Gras J, Sikorski R, Dudziak G, Radhakrishnan R, Gubbins KE. Experimental and simulation studies of melting and freezing in porous glasses Studies in Surface Science and Catalysis. 128: 141-150. DOI: 10.1016/S0167-2991(00)80017-8 |
0.491 |
|
1999 |
Gelb LD, Gubbins KE, Radhakrishnan R, Sliwinska-Bartkowiak M. Phase separation in confined systems Reports On Progress in Physics. 62: 1573-1659. DOI: 10.1088/0034-4885/62/12/201 |
0.664 |
|
1999 |
Radhakrishnan R, Gubbins KE. Free energy studies of freezing in slit pores: An order-parameter approach using Monte Carlo simulation Molecular Physics. 96: 1249-1267. DOI: 10.1080/00268979909483070 |
0.5 |
|
1999 |
Radhakrishnan R, Gubbins KE, Watanabe A, Kaneko K. Freezing of simple fluids in microporous activated carbon fibers: Comparison of simulation and experiment Journal of Chemical Physics. 111: 9058-9067. DOI: 10.1063/1.480261 |
0.51 |
|
1999 |
Sliwinska-Bartkowiak M, Gras J, Sikorski R, Radhakrishnan R, Gelb LD, Gubbins KE. Phase Transitions in Pores: Experimental and Simulation Studies of Melting and Freezing† Langmuir. 15: 6060-6069. DOI: 10.1021/La9814642 |
0.498 |
|
1997 |
Radhakrishnan R, Gubbins KE. Quasi-one-dimensional phase transitions in nanopores: Pore-pore correlation effects Physical Review Letters. 79: 2847-2850. DOI: 10.1103/Physrevlett.79.2847 |
0.486 |
|
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