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Emadeddin Tajkhorshid - Publications

Affiliations: 
University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
General Biophysics
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70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ge J, Elferich J, Dehghani-Ghahnaviyeh S, Zhao Z, Meadows M, von Gersdorff H, Tajkhorshid E, Gouaux E. Molecular mechanism of prestin electromotive signal amplification. Cell. PMID 34390643 DOI: 10.1016/j.cell.2021.07.034  0.309
2021 Kapoor K, Pant S, Tajkhorshid E. Active participation of membrane lipids in inhibition of multidrug transporter P-glycoprotein. Chemical Science. 12: 6293-6306. PMID 34084427 DOI: 10.1039/d0sc06288j  0.333
2021 Haloi N, Wen PC, Cheng Q, Yang M, Natarajan G, Camara AKS, Kwok WM, Tajkhorshid E. Structural basis of complex formation between mitochondrial anion channel VDAC1 and Hexokinase-II. Communications Biology. 4: 667. PMID 34083717 DOI: 10.1038/s42003-021-02205-y  0.307
2020 Lam K, Tajkhorshid E. Membrane Interactions of Cy3 and Cy5 Fluorophores and Their Effects on Membrane-Protein Dynamics. Biophysical Journal. PMID 32533943 DOI: 10.1016/J.Bpj.2020.05.027  0.321
2020 Kumar P, Wang Y, Zhang Z, Zhao Z, Cymes GD, Tajkhorshid E, Grosman C. Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayer. Proceedings of the National Academy of Sciences of the United States of America. PMID 31911476 DOI: 10.1073/Pnas.1906823117  0.309
2019 Jiang T, Wen PC, Trebesch N, Zhao Z, Pant S, Kapoor K, Shekhar M, Tajkhorshid E. Computational Dissection of Membrane Transport at a Microscopic Level. Trends in Biochemical Sciences. PMID 31813734 DOI: 10.1016/J.Tibs.2019.09.001  0.308
2019 Pant S, Tajkhorshid E. Microscopic Characterization of GRP1 PH Domain Interaction with Anionic Membranes. Journal of Computational Chemistry. PMID 31762060 DOI: 10.1002/Jcc.26109  0.335
2019 Martens C, Shekhar M, Lau AM, Tajkhorshid E, Politis A. Integrating hydrogen-deuterium exchange mass spectrometry with molecular dynamics simulations to probe lipid-modulated conformational changes in membrane proteins. Nature Protocols. PMID 31605097 DOI: 10.1038/S41596-019-0219-6  0.307
2019 Muller MP, Jiang T, Sun C, Lihan M, Pant S, Mahinthichaichan P, Trifan A, Tajkhorshid E. Characterization of Lipid-Protein Interactions and Lipid-Mediated Modulation of Membrane Protein Function through Molecular Simulation. Chemical Reviews. PMID 30978005 DOI: 10.1021/Acs.Chemrev.8B00608  0.308
2018 Martens C, Shekhar M, Borysik AJ, Lau AM, Reading E, Tajkhorshid E, Booth PJ, Politis A. Direct protein-lipid interactions shape the conformational landscape of secondary transporters. Nature Communications. 9: 4151. PMID 30297844 DOI: 10.1016/J.Bpj.2018.11.2987  0.326
2017 Tietjen GT, Baylon JL, Kerr D, Gong Z, Henderson JM, Heffern CTR, Meron M, Lin B, Schlossman ML, Adams EJ, Tajkhorshid E, Lee KYC. Coupling X-Ray Reflectivity and In Silico Binding to Yield Dynamics of Membrane Recognition by Tim1. Biophysical Journal. 113: 1505-1519. PMID 28978444 DOI: 10.1016/J.Bpj.2017.08.003  0.332
2017 Jiang T, Yu K, Hartzell HC, Tajkhorshid E. Lipids and ions traverse the membrane by the same physical pathway in the nhTMEM16 scramblase. Elife. 6. PMID 28917060 DOI: 10.7554/eLife.28671  0.31
2017 Vermaas JV, Tajkhorshid E. Differential Membrane Binding Mechanics of Synaptotagmin Isoforms Observed in Atomic Detail. Biochemistry. 56: 281-293. PMID 27997124 DOI: 10.1021/Acs.Biochem.6B00468  0.321
2017 Zhao Z, Tajkhorshid E. Characterizing Outward- to Inward-Facing Transition Pathway of Dopamine Transporter Biophysical Journal. 112: 128a. DOI: 10.1016/J.Bpj.2016.11.713  0.31
2017 Kerr D, Gong Z, Tietjen G, Baylon J, Hwang L, Henderson JM, Lin B, Meron M, Bu W, Schlossman M, Tajkhorshid E, Adams E, Yee Lee K. Membrane Bound Structures of Peripheral Membrane Binding Proteins TIM3 and TIM1 Produced by Molecular Dynamics Informed Analysis of X-Ray Scattering Experiments Biophysical Journal. 112: 391a. DOI: 10.1016/J.Bpj.2016.11.2122  0.315
2016 Vermaas JV, Trebesch N, Mayne CG, Thangapandian S, Shekhar M, Mahinthichaichan P, Baylon JL, Jiang T, Wang Y, Muller MP, Shinn E, Zhao Z, Wen PC, Tajkhorshid E. Microscopic Characterization of Membrane Transporter Function by In Silico Modeling and Simulation. Methods in Enzymology. 578: 373-428. PMID 27497175 DOI: 10.1016/Bs.Mie.2016.05.042  0.332
2016 Vermaas JV, Tajkhorshid E. Electrostatic Lock Controlling Structural Transition in the EmrE Polyaromatic Cation Transporter Biophysical Journal. 110: 628a. DOI: 10.1016/J.Bpj.2015.11.3365  0.33
2016 Muller MP, Tajkhorshid E. Molecular Basis for Lipid Specificity of the Coagulation Factor X Membrane-Binding Domain Biophysical Journal. 110: 424a. DOI: 10.1016/J.Bpj.2015.11.2291  0.324
2016 Jiang T, Thangapandian S, Tajkhorshid E. Functional Characterization of Calcium-activated Phospholipid Scramblase Activity of nhTMEM16 Biophysical Journal. 110: 179a-180a. DOI: 10.1016/J.Bpj.2015.11.1001  0.302
2015 Vermaas JV, Baylon JL, Arcario MJ, Muller MP, Wu Z, Pogorelov TV, Tajkhorshid E. Efficient Exploration of Membrane-Associated Phenomena at Atomic Resolution. The Journal of Membrane Biology. 248: 563-82. PMID 25998378 DOI: 10.1007/S00232-015-9806-9  0.317
2015 Li J, Wen PC, Moradi M, Tajkhorshid E. Computational characterization of structural dynamics underlying function in active membrane transporters. Current Opinion in Structural Biology. 31: 96-105. PMID 25913536 DOI: 10.1016/J.Sbi.2015.04.001  0.321
2015 Vermaas JV, Tajkhorshid E. Strength, Not Depth: An Exploration of Differential Membrane Binding Kinetics of Synaptotagmin-1 and Synaptotagmin-7 C2 Domains Biophysical Journal. 108: 555a. DOI: 10.1016/J.Bpj.2014.11.3045  0.315
2015 Tajkhorshid E, Moradi M, Li J, Wen P, Thangapandian S, Vermaas J. Advances in Atomic-Level Simulations of Large-Scale Functional Motions of Membrane Transporters Biophysical Journal. 108: 371a. DOI: 10.1016/J.Bpj.2014.11.2032  0.344
2015 Baylon JL, Tietjen GT, Lee KYC, Adams EJ, Tajkhorshid E. Molecular Details of the Mechanism of PS Recognition by TIM Proteins Biophysical Journal. 108: 248a-249a. DOI: 10.1016/J.Bpj.2014.11.1375  0.333
2014 Blanchard AE, Arcario MJ, Schulten K, Tajkhorshid E. A highly tilted membrane configuration for the prefusion state of synaptobrevin. Biophysical Journal. 107: 2112-21. PMID 25418096 DOI: 10.1016/J.Bpj.2014.09.013  0.327
2014 Arcario MJ, Tajkhorshid E. Membrane-induced structural rearrangement and identification of a novel membrane anchor in talin F2F3. Biophysical Journal. 107: 2059-69. PMID 25418091 DOI: 10.1016/J.Bpj.2014.09.022  0.314
2014 Arcario MJ, Mayne CG, Tajkhorshid E. Atomistic models of general anesthetics for use in in silico biological studies. The Journal of Physical Chemistry. B. 118: 12075-86. PMID 25303275 DOI: 10.1021/Jp502716M  0.326
2014 Vermaas JV, Tajkhorshid E. Conformational heterogeneity of α-synuclein in membrane. Biochimica Et Biophysica Acta. 1838: 3107-17. PMID 25135664 DOI: 10.1016/J.Bbamem.2014.08.012  0.339
2014 Skeby KK, Tajkhorshid E, Birgit S. Capturing Spontaneous Binding of Human Islet Amyloid Polypeptide to Anionic Membranes using a Highly Mobile Membrane Mimetic Model Biophysical Journal. 106: 98a. DOI: 10.1016/J.Bpj.2013.11.614  0.334
2014 Wen P, Tajkhorshid E. Multiple Membrane-Compatible Conformations of an Substrate-Binding Component of ECF Transporters Biophysical Journal. 106: 790a. DOI: 10.1016/J.Bpj.2013.11.4330  0.325
2014 Arcario MJ, Tajkhorshid E. Utilizing Non-Equilibrium Methods to Probe the Effects of General Anesthetics on Ligand-Gated Ion Channel Dynamics Biophysical Journal. 106: 545a-546a. DOI: 10.1016/J.Bpj.2013.11.3039  0.305
2014 Shekhar M, Enkavi G, Tajkhorshid E. An Insight into the XylE Transport Cycle by Characterizing Proton Binding Site and its Coupling to the Substrate Transport Biophysical Journal. 106: 367a. DOI: 10.1016/J.Bpj.2013.11.2081  0.323
2014 Li J, Tajkhorshid E. Coupling of Ion Binding and Conformational Equilibrium in Na+-Driven Secondary Active Transporters Biophysical Journal. 106: 366a. DOI: 10.1016/J.Bpj.2013.11.2074  0.304
2014 Baylon J, Tajkhorshid E. Probing Ligand Dynamics in Membrane-Bound Cytochrome P450 3A4 to Characterize Substrate Access and Product Egress Pathways Biophysical Journal. 106: 13a. DOI: 10.1016/J.Bpj.2013.11.127  0.311
2014 Enkavi G, Li J, Wen P, Thangapandian S, Moradi M, Jiang T, Han W, Tajkhorshid E. A microscopic view of the mechanisms of active transport across the cellular membrane Annual Reports in Computational Chemistry. 10: 77-125. DOI: 10.1016/B978-0-444-63378-1.00004-5  0.329
2013 Moradi M, Tajkhorshid E. Mechanistic picture for conformational transition of a membrane transporter at atomic resolution. Proceedings of the National Academy of Sciences of the United States of America. 110: 18916-21. PMID 24191018 DOI: 10.1073/Pnas.1313202110  0.32
2013 Baylon JL, Lenov IL, Sligar SG, Tajkhorshid E. Characterizing the membrane-bound state of cytochrome P450 3A4: structure, depth of insertion, and orientation. Journal of the American Chemical Society. 135: 8542-51. PMID 23697766 DOI: 10.1021/Ja4003525  0.32
2013 Wen PC, Verhalen B, Wilkens S, Mchaourab HS, Tajkhorshid E. On the origin of large flexibility of P-glycoprotein in the inward-facing state. The Journal of Biological Chemistry. 288: 19211-20. PMID 23658020 DOI: 10.1074/Jbc.M113.450114  0.336
2013 Li J, Shaikh SA, Enkavi G, Wen PC, Huang Z, Tajkhorshid E. Transient formation of water-conducting states in membrane transporters. Proceedings of the National Academy of Sciences of the United States of America. 110: 7696-701. PMID 23610412 DOI: 10.1073/Pnas.1218986110  0.312
2013 Enkavi G, Li J, Mahinthichaichan P, Wen PC, Huang Z, Shaikh SA, Tajkhorshid E. Simulation studies of the mechanism of membrane transporters. Methods in Molecular Biology (Clifton, N.J.). 924: 361-405. PMID 23034756 DOI: 10.1007/978-1-62703-017-5_14  0.335
2013 Baylon JL, Tajkhorshid E. Probing Substrate Access Pathways of the Active Site of Cytochrome P450 3A4 in its Membrane-Bound Form Biophysical Journal. 104: 561a. DOI: 10.1016/J.Bpj.2012.11.3108  0.308
2013 Ohkubo Y, Tajkhorshid E. Exploring Membrane-Bound form of the C2 Domain by HMMM Model Biophysical Journal. 104: 432a. DOI: 10.1016/J.Bpj.2012.11.2405  0.317
2013 Li J, Tajkhorshid E. Ion-Coupling of Conformational Equilibrium and Transition in Secondary Active Transporters Biophysical Journal. 104: 288a. DOI: 10.1016/J.Bpj.2012.11.1613  0.317
2013 Stolzenberg S, Huang Z, Mondal S, Weinstein H, Tajkhorshid E. Structural Transition between the Inward- and Outward-Facing States of the Glutamate Transporter in Different Lipid Environments Biophysical Journal. 104: 288a. DOI: 10.1016/J.Bpj.2012.11.1612  0.344
2013 Arcario MJ, Tajkhorshid E. Mechanism, Energetics, and Pathways for Association and Binding of Anesthetics to Membranes and Membrane Channels Biophysical Journal. 104: 208a. DOI: 10.1016/J.Bpj.2012.11.1177  0.33
2012 Ohkubo YZ, Pogorelov TV, Arcario MJ, Christensen GA, Tajkhorshid E. Accelerating membrane insertion of peripheral proteins with a novel membrane mimetic model. Biophysical Journal. 102: 2130-9. PMID 22824277 DOI: 10.1016/J.Bpj.2012.03.015  0.313
2012 Morrissey JH, Tajkhorshid E, Sligar SG, Rienstra CM. Tissue factor/factor VIIa complex: role of the membrane surface. Thrombosis Research. 129: S8-10. PMID 22417943 DOI: 10.1016/J.Thromres.2012.02.019  0.301
2012 Vermaas JV, Tajkhorshid E. Conformational Dynamics of Membrane-Bound α-Synuclein in a Highly Mobile Membrane Mimetic Biophysical Journal. 102: 493a. DOI: 10.1016/J.Bpj.2011.11.2700  0.336
2012 Baylon JL, Tajkhorshid E. Capturing Insertion and Dynamics of Membrane-Bound Cytochrome P450 3A4 using a Novel Membrane Mimetic Model Biophysical Journal. 102: 466a. DOI: 10.1016/J.Bpj.2011.11.2557  0.332
2012 Gan W, Moradi M, Tajkhorshid E. Characterizing Transition Pathways in the Transport Cycle of ABC Transporter MsbA Biophysical Journal. 102: 446a. DOI: 10.1016/J.Bpj.2011.11.2446  0.311
2012 Pogorelov TV, Tajkhorshid E. Glycophorin a Helix Insertion, Positioning, and Dimerization in Model Membranes Biophysical Journal. 102: 413a. DOI: 10.1016/J.Bpj.2011.11.2260  0.337
2012 Arcario MJ, Tajkhorshid E. Capturing Spontaneous Membrane Insertion and Membrane-Induced Conformational Changes of Talin at an Atomic Resolution Biophysical Journal. 102: 301a. DOI: 10.1016/J.Bpj.2011.11.1667  0.312
2011 Arcario MJ, Ohkubo YZ, Tajkhorshid E. Capturing spontaneous partitioning of peripheral proteins using a biphasic membrane-mimetic model. The Journal of Physical Chemistry. B. 115: 7029-37. PMID 21561114 DOI: 10.1021/Jp109631Y  0.303
2011 Arcario MJ, Tajkhorshid E. Dynamic Characterization of the Membrane-Mediated Activation of Integrin by Talin At Atomic Reoslution Blood. 118: 2191-2191. DOI: 10.1182/Blood.V118.21.2191.2191  0.327
2011 Enkavi G, Levin EJ, Zhou M, Tajkhorshid E. Energetics and Molecular Mechanisms of Permeation and Selectivity of Transport in the Urea Transporter Biophysical Journal. 100: 90a-91a. DOI: 10.1016/J.Bpj.2010.12.700  0.306
2011 Ohkubo YZ, Pogorelov TV, Arcario MJ, Tajkhorshid E. Spontaneous Binding of Membrane-Anchoring Proteins Captured with a Highly Mobile Membrane-Mimetic Model Biophysical Journal. 100: 639a-640a. DOI: 10.1016/J.Bpj.2010.12.3674  0.316
2011 Arcario MJ, Tajkhorshid E. Membrane Insertion and Membrane-Induced Conformational Changes of Talin F2F3 Triggering Integrin Activation Biophysical Journal. 100: 254a-255a. DOI: 10.1016/J.Bpj.2010.12.1607  0.311
2010 Shaikh S, Wen PC, Enkavi G, Huang Z, Tajkhorshid E. Capturing Functional Motions of Membrane Channels and Transporters with Molecular Dynamics Simulation. Journal of Computational and Theoretical Nanoscience. 7: 2481-2500. PMID 23710155 DOI: 10.1166/Jctn.2010.1636  0.34
2010 Morrissey JH, Davis-Harrison RL, Tavoosi N, Ke K, Pureza V, Boettcher JM, Clay MC, Rienstra CM, Ohkubo YZ, Pogorelov TV, Tajkhorshid E. Protein-phospholipid interactions in blood clotting. Thrombosis Research. 125: S23-5. PMID 20129649 DOI: 10.1016/J.Thromres.2010.01.027  0.306
2010 Enkavi G, Tajkhorshid E. Simulation of spontaneous substrate binding revealing the binding pathway and mechanism and initial conformational response of GlpT. Biochemistry. 49: 1105-14. PMID 20058936 DOI: 10.1021/Bi901412A  0.344
2010 Arcario MJ, Tajkhorshid E. Characterizing Membrane-Bound Forms of Coagulation Factors at Atomic Resolution: Exploring Differences In Membrane Affinity. Blood. 116: 1139-1139. DOI: 10.1182/Blood.V116.21.1139.1139  0.324
2010 Pogorelov T, Ohkubo YZ, Tajkhorshid E. Characterizing the Structure and Dynamics of Nanodisc Lipid Bilayers of Different Compositions Biophysical Journal. 98: 665a. DOI: 10.1016/J.Bpj.2009.12.4257  0.322
2010 Ohkubo YZ, Tajkhorshid E. Dynamical Basis of the Enhancement of the Enzymatic Activity of Factor VIIa by Tissue Factor Biophysical Journal. 98: 689a. DOI: 10.1016/J.Bpj.2009.12.3787  0.309
2010 Wen P, Tajkhorshid E. The Origin of Nucleotide Dependence of Conformational Changes in ABC Transporters Biophysical Journal. 98: 627a-628a. DOI: 10.1016/J.Bpj.2009.12.3436  0.303
2010 Tajkhorshid E. A Dynamical View of Membrane Transporter Function at Sub-Angstrom Resolution Biophysical Journal. 98: 211a. DOI: 10.1016/J.Bpj.2009.12.1138  0.346
2009 Morrissey JH, Pureza V, Davis-Harrison RL, Sligar SG, Rienstra CM, Kijac AZ, Ohkubo YZ, Tajkhorshid E. Protein-membrane interactions: blood clotting on nanoscale bilayers. Journal of Thrombosis and Haemostasis : Jth. 7: 169-72. PMID 19630793 DOI: 10.1111/J.1538-7836.2009.03390.X  0.304
2008 Celik L, Schiøtt B, Tajkhorshid E. Substrate binding and formation of an occluded state in the leucine transporter. Biophysical Journal. 94: 1600-12. PMID 18024499 DOI: 10.1529/Biophysj.107.117580  0.303
2006 Yin Y, Jensen MØ, Tajkhorshid E, Schulten K. Sugar binding and protein conformational changes in lactose permease. Biophysical Journal. 91: 3972-85. PMID 16963502 DOI: 10.1529/Biophysj.106.085993  0.373
2005 Gumbart J, Wang Y, Aksimentiev A, Tajkhorshid E, Schulten K. Molecular dynamics simulations of proteins in lipid bilayers Current Opinion in Structural Biology. 15: 423-431. PMID 16043343 DOI: 10.1016/J.Sbi.2005.07.007  0.319
2000 Tajkhorshid E, Baudry J, Schulten K, Suhai S. Molecular dynamics study of the nature and origin of retinal's twisted structure in bacteriorhodopsin. Biophysical Journal. 78: 683-93. PMID 10653781 DOI: 10.1016/S0006-3495(00)76626-4  0.316
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