Susan Serota Taylor - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Structure, Function, Dynamics, and Localization of PKA as a Prototype for the Protein Kinase Superfamily
Website:
http://www-chem.ucsd.edu/faculty/profiles/taylor_susan_s.html

192 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Haushalter KJ, Schilling JM, Song Y, Sastri M, Perkins GA, Strack S, Taylor SS, Patel HH. Cardiac ischemia/reperfusion injury induces ROS-dependent loss of PKA regulatory subunit RIα. American Journal of Physiology. Heart and Circulatory Physiology. PMID 31674811 DOI: 10.1152/ajpheart.00237.2019  0.44
2019 Walker C, Wang Y, Olivieri C, Karamafrooz A, Casby J, Bathon K, Calebiro D, Gao J, Bernlohr DA, Taylor SS, Veglia G. Cushing's syndrome driver mutation disrupts protein kinase A allosteric network, altering both regulation and substrate specificity. Science Advances. 5: eaaw9298. PMID 31489371 DOI: 10.1126/sciadv.aaw9298  0.44
2019 Lu TW, Wu J, Aoto PC, Weng JH, Ahuja LG, Sun N, Cheng CY, Zhang P, Taylor SS. Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP. Proceedings of the National Academy of Sciences of the United States of America. PMID 31363049 DOI: 10.1073/pnas.1906036116  0.44
2019 Schmidt SH, Knape MJ, Boassa D, Mumdey N, Kornev AP, Ellisman MH, Taylor SS, Herberg FW. The dynamic switch mechanism that leads to activation of LRRK2 is embedded in the DFGψ motif in the kinase domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 31292254 DOI: 10.1073/pnas.1900289116  0.72
2019 Ahuja LG, Aoto PC, Kornev AP, Veglia G, Taylor SS. Dynamic allostery-based molecular workings of kinase:peptide complexes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31285328 DOI: 10.1073/pnas.1900163116  0.72
2019 Ahuja LG, Taylor SS, Kornev AP. Tuning the "violin" of protein kinases: The role of dynamics-based allostery. Iubmb Life. PMID 31063633 DOI: 10.1002/iub.2057  0.72
2019 Taylor SS, Meharena HS, Kornev AP. Evolution of a Dynamic Molecular Switch. Iubmb Life. PMID 31059206 DOI: 10.1002/iub.2059  0.72
2019 Gerlits O, Weiss KL, Blakeley MP, Veglia G, Taylor SS, Kovalevsky A. Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex. Science Advances. 5: eaav0482. PMID 30906862 DOI: 10.1126/sciadv.aav0482  0.44
2019 Cao B, Lu TW, Martinez Fiesco JA, Tomasini M, Fan L, Simon SM, Taylor SS, Zhang P. Structures of the PKA RIα Holoenzyme with the FLHCC Driver J-PKAcα or Wild-Type PKAcα. Structure (London, England : 1993). PMID 30905674 DOI: 10.1016/j.str.2019.03.001  0.36
2019 Wang Y, V S M, Kim J, Li G, Ahuja LG, Aoto P, Taylor SS, Veglia G. Globally correlated conformational entropy underlies positive and negative cooperativity in a kinase's enzymatic cycle. Nature Communications. 10: 799. PMID 30778078 DOI: 10.1038/s41467-019-08655-7  0.44
2019 Zhang P, Fan Y, Ru H, Wang L, Magupalli VG, Taylor SS, Alessi DR, Wu H. Crystal structure of the WD40 domain dimer of LRRK2. Proceedings of the National Academy of Sciences of the United States of America. PMID 30635421 DOI: 10.1073/pnas.1817889116  0.36
2019 Gógl G, Kornev AP, Reményi A, Taylor SS. Disordered Protein Kinase Regions in Regulation of Kinase Domain Cores. Trends in Biochemical Sciences. PMID 30611608 DOI: 10.1016/j.tibs.2018.12.002  0.72
2018 Meng Y, Ahuja LG, Kornev AP, Taylor SS, Roux B. Corrigendum to "A Catalytically-Disabled Double Mutant of Src Tyrosine Kinase Can Be Stabilized into an Active-Like Conformation." J. Mol. Biol. 430(6) (Mar 16 2018), 881-889. Journal of Molecular Biology. PMID 30220583 DOI: 10.1016/j.jmb.2018.09.001  0.72
2018 Meng Y, Ahuja LG, Kornev AP, Taylor SS, Roux B. A Catalytically-Disabled Double Mutant of Src Tyrosine Kinase Can Be Stabilized into an Active-Like Conformation. Journal of Molecular Biology. PMID 29410316 DOI: 10.1016/j.jmb.2018.01.019  0.72
2018 Tomasini MD, Wang Y, Karamafrooz A, Li G, Beuming T, Gao J, Taylor SS, Veglia G, Simon SM. Conformational Landscape of the PRKACA-DNAJB1 Chimeric Kinase, the Driver for Fibrolamellar Hepatocellular Carcinoma. Scientific Reports. 8: 720. PMID 29335433 DOI: 10.1038/s41598-017-18956-w  0.44
2017 Bubis J, Martínez JC, Calabokis M, Ferreira J, Sanz-Rodríguez CE, Navas V, Escalona JL, Guo Y, Taylor SS. The gene product of a Trypanosoma equiperdum ortholog of the cAMP-dependent protein kinase regulatory subunit is a monomeric protein that is not capable of binding cyclic nucleotides. Biochimie. PMID 29288679 DOI: 10.1016/j.biochi.2017.12.010  1
2017 Sastri M, Darshi M, Mackey M, Ramachandra R, Ju S, Phan S, Adams S, Stein K, Douglas CR, Kim JJ, Ellisman MH, Taylor SS, Perkins GA. Sub-mitochondrial localization of genetic-tagged MIB interacting partners: Mic19, Mic60 and Sam50. Journal of Cell Science. PMID 28808085 DOI: 10.1242/jcs.201400  0.44
2017 Kim J, Ahuja LG, Chao FA, Xia Y, McClendon CL, Kornev AP, Taylor SS, Veglia G. A dynamic hydrophobic core orchestrates allostery in protein kinases. Science Advances. 3: e1600663. PMID 28435869 DOI: 10.1126/sciadv.1600663  0.72
2017 Pecora de Barros E, Malmstrom RD, Nourbakhsh K, Del Rio JC, Kornev AP, Taylor SS, Amaro RE. Electrostatic interactions as mediators in the allosteric activation of PKA RIα. Biochemistry. PMID 28221775 DOI: 10.1021/acs.biochem.6b01152  0.72
2017 Ahuja LG, Kornev AP, McClendon CL, Veglia G, Taylor SS. Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer. Proceedings of the National Academy of Sciences of the United States of America. PMID 28115705 DOI: 10.1073/pnas.1620667114  0.72
2016 Meharena HS, Fan X, Ahuja LG, Keshwani MM, McClendon CL, Chen AM, Adams JA, Taylor SS. Decoding the Interactions Regulating the Active State Mechanics of Eukaryotic Protein Kinases. Plos Biology. 14: e2000127. PMID 27902690 DOI: 10.1371/journal.pbio.2000127  0.56
2016 Bruystens JG, Wu J, Fortezzo A, Del Rio J, Nielsen C, Blumenthal DK, Rock R, Stefan E, Taylor SS. Structure of a PKA RIα Recurrent Acrodysostosis Mutant Explains Defective cAMP-Dependent Activation. Journal of Molecular Biology. PMID 27825928 DOI: 10.1016/j.jmb.2016.10.033  0.4
2016 Bachmann VA, Mayrhofer JE, Ilouz R, Tschaikner P, Raffeiner P, Röck R, Courcelles M, Apelt F, Lu TW, Baillie GS, Thibault P, Aanstad P, Stelzl U, Taylor SS, Stefan E. Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 27357676 DOI: 10.1073/pnas.1608061113  0.36
2016 Burgers PP, Bruystens J, Burnley RJ, Nikolaev VO, Keshwani M, Wu J, Janssen BJ, Taylor SS, Heck AJ, Scholten A. Structure of smAKAP and its regulation by PKA-mediated phosphorylation. The Febs Journal. PMID 27028580 DOI: 10.1111/febs.13726  0.32
2016 Kim J, Li G, Walters MA, Taylor SS, Veglia G. Uncoupling Catalytic and Binding Functions in the Cyclic AMP-Dependent Protein Kinase A. Structure (London, England : 1993). PMID 26833386 DOI: 10.1016/j.str.2015.11.016  0.4
2016 Chávez-Vargas L, Adame-García SR, Cervantes-Villagrana RD, Castillo-Kauil A, Bruystens JG, Fukuhara S, Taylor SS, Mochizuki N, Reyes-Cruz G, Vázquez-Prado J. Protein kinase A (PKA) Type I interacts with P-Rex1, a Rac guanine nucleotide exchange factor: Effect on PKA localization and P-Rex1 signaling. The Journal of Biological Chemistry. PMID 26797121 DOI: 10.1074/jbc.M115.712216  0.4
2015 Baeza-Raja B, Sachs BD, Li P, Christian F, Vagena E, Davalos D, Le Moan N, Ryu JK, Sikorski SL, Chan JP, Scadeng M, Taylor SS, Houslay MD, Baillie GS, Saltiel AR, et al. p75 Neurotrophin Receptor Regulates Energy Balance in Obesity. Cell Reports. PMID 26748707 DOI: 10.1016/j.celrep.2015.12.028  0.4
2015 Akimoto M, McNicholl ET, Ramkissoon A, Moleschi K, Taylor SS, Melacini G. Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα. Plos Biology. 13: e1002305. PMID 26618408 DOI: 10.1371/journal.pbio.1002305  1
2015 Kornev AP, Taylor SS. Dynamics-Driven Allostery in Protein Kinases. Trends in Biochemical Sciences. 40: 628-47. PMID 26481499 DOI: 10.1016/j.tibs.2015.09.002  1
2015 Keshwani MM, Kanter JR, Ma Y, Wilderman A, Darshi M, Insel PA, Taylor SS. Mechanisms of cyclic AMP/protein kinase A- and glucocorticoid-mediated apoptosis using S49 lymphoma cells as a model system. Proceedings of the National Academy of Sciences of the United States of America. PMID 26417071 DOI: 10.1073/pnas.1516057112  1
2015 Antal CE, Callender JA, Kornev AP, Taylor SS, Newton AC. Intramolecular C2 Domain-Mediated Autoinhibition of Protein Kinase C βII. Cell Reports. 12: 1252-60. PMID 26279568 DOI: 10.1016/j.celrep.2015.07.039  1
2015 Zhang P, Ye F, Bastidas AC, Kornev AP, Wu J, Ginsberg MH, Taylor SS. An Isoform-Specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes. Structure (London, England : 1993). PMID 26278174 DOI: 10.1016/j.str.2015.07.007  1
2015 Wilderman A, Guo Y, Divakaruni AS, Perkins G, Zhang L, Murphy AN, Taylor SS, Insel PA. Proteomic and Metabolic Analyses of S49 Lymphoma Cells Reveal Novel Regulation of Mitochondria by cAMP and Protein Kinase A. The Journal of Biological Chemistry. 290: 22274-86. PMID 26203188 DOI: 10.1074/jbc.M115.658153  1
2015 Knape MJ, Ahuja LG, Bertinetti D, Burghardt NC, Zimmermann B, Taylor SS, Herberg FW. Divalent Metal Ions Mg(2+) and Ca(2+) Have Distinct Effects on Protein Kinase A Activity and Regulation. Acs Chemical Biology. 10: 2303-15. PMID 26200257 DOI: 10.1021/acschembio.5b00271  1
2015 Zhang P, Knape MJ, Ahuja LG, Keshwani MM, King CC, Sastri M, Herberg FW, Taylor SS. Single Turnover Autophosphorylation Cycle of the PKA RIIβ Holoenzyme. Plos Biology. 13: e1002192. PMID 26158466 DOI: 10.1371/journal.pbio.1002192  1
2015 Malmstrom RD, Kornev AP, Taylor SS, Amaro RE. Allostery through the computational microscope: cAMP activation of a canonical signalling domain. Nature Communications. 6: 7588. PMID 26145448 DOI: 10.1038/ncomms8588  0.72
2015 Zhang P, Kornev AP, Wu J, Taylor SS. Discovery of Allostery in PKA Signaling. Biophysical Reviews. 7: 227-238. PMID 26097522 DOI: 10.1007/s12551-015-0170-x  0.72
2015 Schmidts M, Hou Y, Cortés CR, Mans DA, Huber C, Boldt K, Patel M, van Reeuwijk J, Plaza JM, van Beersum SE, Yap ZM, Letteboer SJ, Taylor SP, Herridge W, Johnson CA, et al. TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport. Nature Communications. 6: 7074. PMID 26044572 DOI: 10.1038/ncomms8074  0.32
2015 Li GC, Srivastava AK, Kim J, Taylor SS, Veglia G. Mapping the Hydrogen Bond Networks in the Catalytic Subunit of Protein Kinase A Using H/D Fractionation Factors. Biochemistry. 54: 4042-9. PMID 26030372 DOI: 10.1021/acs.biochem.5b00387  1
2015 Wei SC, Fattet L, Tsai JH, Guo Y, Pai VH, Majeski HE, Chen AC, Sah RL, Taylor SS, Engler AJ, Yang J. Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway. Nature Cell Biology. 17: 678-88. PMID 25893917 DOI: 10.1038/ncb3157  0.4
2015 Taylor SS, Shaw AS, Kannan N, Kornev AP. Integration of signaling in the kinome: Architecture and regulation of the αC Helix. Biochimica Et Biophysica Acta. PMID 25891902 DOI: 10.1016/j.bbapap.2015.04.007  1
2015 Mohanty S, Kennedy EJ, Herberg FW, Hui R, Taylor SS, Langsley G, Kannan N. Structural and evolutionary divergence of cyclic nucleotide binding domains in eukaryotic pathogens: Implications for drug design. Biochimica Et Biophysica Acta. PMID 25847873 DOI: 10.1016/j.bbapap.2015.03.012  1
2015 Kim J, Masterson LR, Cembran A, Verardi R, Shi L, Gao J, Taylor SS, Veglia G. Dysfunctional conformational dynamics of protein kinase A induced by a lethal mutant of phospholamban hinder phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 112: 3716-21. PMID 25775607 DOI: 10.1073/pnas.1502299112  1
2015 McSkimming DI, Dastgheib S, Talevich E, Narayanan A, Katiyar S, Taylor SS, Kochut K, Kannan N. ProKinO: a unified resource for mining the cancer kinome. Human Mutation. 36: 175-86. PMID 25382819 DOI: 10.1002/humu.22726  1
2015 Niyitegeka JM, Bastidas AC, Newman RH, Taylor SS, Ongeri EM. Isoform-specific interactions between meprin metalloproteases and the catalytic subunit of protein kinase A: significance in acute and chronic kidney injury. American Journal of Physiology. Renal Physiology. 308: F56-68. PMID 25354939 DOI: 10.1152/ajprenal.00167.2014  1
2015 Hu J, Ahuja LG, Meharena HS, Kannan N, Kornev AP, Taylor SS, Shaw AS. Kinase regulation by hydrophobic spine assembly in cancer. Molecular and Cellular Biology. 35: 264-76. PMID 25348715 DOI: 10.1128/MCB.00943-14  1
2015 Sarma GN, Moody IS, Ilouz R, Phan RH, Sankaran B, Hall RA, Taylor SS. D-AKAP2:PKA RII:PDZK1 ternary complex structure: insights from the nucleation of a polyvalent scaffold. Protein Science : a Publication of the Protein Society. 24: 105-16. PMID 25348485 DOI: 10.1002/pro.2593  1
2015 Bastidas AC, Wu J, Taylor SS. Molecular features of product release for the PKA catalytic cycle. Biochemistry. 54: 2-10. PMID 25077557 DOI: 10.1021/bi500684c  1
2015 Malmstrom RD, Kornev AP, Taylor SS, Amaro RE. Allostery through the computational microscope: CAMP activation of a canonical signalling domain Nature Communications. 6. DOI: 10.1038/ncomms8588  1
2014 Srivastava AK, McDonald LR, Cembran A, Kim J, Masterson LR, McClendon CL, Taylor SS, Veglia G. Synchronous opening and closing motions are essential for cAMP-dependent protein kinase A signaling. Structure (London, England : 1993). 22: 1735-43. PMID 25458836 DOI: 10.1016/j.str.2014.09.010  1
2014 McClendon CL, Kornev AP, Gilson MK, Taylor SS. Dynamic architecture of a protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 111: E4623-31. PMID 25319261 DOI: 10.1073/pnas.1418402111  0.72
2014 Boras BW, Kornev A, Taylor SS, McCulloch AD. Using Markov state models to develop a mechanistic understanding of protein kinase A regulatory subunit RIα activation in response to cAMP binding. The Journal of Biological Chemistry. 289: 30040-51. PMID 25202018 DOI: 10.1074/jbc.M114.568907  1
2014 Blumenthal DK, Copps J, Smith-Nguyen EV, Zhang P, Heller WT, Taylor SS. The roles of the RIIβ linker and N-terminal cyclic nucleotide-binding domain in determining the unique structures of the type IIβ protein kinase A: a small angle x-ray and neutron scattering study. The Journal of Biological Chemistry. 289: 28505-12. PMID 25112875 DOI: 10.1074/jbc.M114.584177  1
2014 Shaw AS, Kornev AP, Hu J, Ahuja LG, Taylor SS. Kinases and pseudokinases: lessons from RAF. Molecular and Cellular Biology. 34: 1538-46. PMID 24567368 DOI: 10.1128/MCB.00057-14  1
2014 Akimoto M, Moleschi K, Boulton S, VanSchouwen B, Selvaratnam R, Taylor SS, Melacini G. Allosteric linkers in cAMP signalling. Biochemical Society Transactions. 42: 139-44. PMID 24450641 DOI: 10.1042/BST20130257  1
2014 Bruystens JG, Wu J, Fortezzo A, Kornev AP, Blumenthal DK, Taylor SS. PKA RIα homodimer structure reveals an intermolecular interface with implications for cooperative cAMP binding and Carney complex disease. Structure (London, England : 1993). 22: 59-69. PMID 24316401 DOI: 10.1016/j.str.2013.10.012  1
2013 Meharena HS, Chang P, Keshwani MM, Oruganty K, Nene AK, Kannan N, Taylor SS, Kornev AP. Deciphering the structural basis of eukaryotic protein kinase regulation. Plos Biology. 11: e1001680. PMID 24143133 DOI: 10.1371/journal.pbio.1001680  0.72
2013 Okada H, Lai NC, Kawaraguchi Y, Liao P, Copps J, Sugano Y, Okada-Maeda S, Banerjee I, Schilling JM, Gingras AR, Asfaw EK, Suarez J, Kang SM, Perkins GA, Au CG, ... ... Taylor SS, et al. Integrins protect cardiomyocytes from ischemia/reperfusion injury. The Journal of Clinical Investigation. 123: 4294-308. PMID 24091324 DOI: 10.1172/JCI64216  1
2013 Guo Y, Darshi M, Ma Y, Perkins GA, Shen Z, Haushalter KJ, Saito R, Chen A, Lee YS, Patel HH, Briggs SP, Ellisman MH, Olefsky JM, Taylor SS. Quantitative proteomic and functional analysis of liver mitochondria from high fat diet (HFD) diabetic mice. Molecular & Cellular Proteomics : McP. 12: 3744-58. PMID 24030101 DOI: 10.1074/mcp.M113.027441  1
2013 Bastidas AC, Pierce LC, Walker RC, Johnson DA, Taylor SS. Influence of N-myristylation and ligand binding on the flexibility of the catalytic subunit of protein kinase A. Biochemistry. 52: 6368-79. PMID 24003983 DOI: 10.1021/bi400575k  1
2013 Hu J, Stites EC, Yu H, Germino EA, Meharena HS, Stork PJ, Kornev AP, Taylor SS, Shaw AS. Allosteric activation of functionally asymmetric RAF kinase dimers. Cell. 154: 1036-46. PMID 23993095 DOI: 10.1016/j.cell.2013.07.046  1
2013 Brown SH, Cheng CY, Saldanha SA, Wu J, Cottam HB, Sankaran B, Taylor SS. Implementing fluorescence anisotropy screening and crystallographic analysis to define PKA isoform-selective activation by cAMP analogs. Acs Chemical Biology. 8: 2164-72. PMID 23978166 DOI: 10.1021/cb400247t  0.32
2013 Akimoto M, Selvaratnam R, McNicholl ET, Verma G, Taylor SS, Melacini G. Signaling through dynamic linkers as revealed by PKA. Proceedings of the National Academy of Sciences of the United States of America. 110: 14231-6. PMID 23946424 DOI: 10.1073/pnas.1312644110  1
2013 Taylor SS, Shaw A, Hu J, Meharena HS, Kornev A. Pseudokinases from a structural perspective. Biochemical Society Transactions. 41: 981-6. PMID 23863167 DOI: 10.1042/BST20130120  1
2013 Laanemets K, Brandt B, Li J, Merilo E, Wang YF, Keshwani MM, Taylor SS, Kollist H, Schroeder JI. Calcium-dependent and -independent stomatal signaling network and compensatory feedback control of stomatal opening via Ca2+ sensitivity priming. Plant Physiology. 163: 504-13. PMID 23766366 DOI: 10.1104/pp.113.220343  0.56
2013 Yu FX, Zhang Y, Park HW, Jewell JL, Chen Q, Deng Y, Pan D, Taylor SS, Lai ZC, Guan KL. Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation. Genes & Development. 27: 1223-32. PMID 23752589 DOI: 10.1101/gad.219402.113  1
2013 Taylor SS, Zhang P, Steichen JM, Keshwani MM, Kornev AP. PKA: lessons learned after twenty years. Biochimica Et Biophysica Acta. 1834: 1271-8. PMID 23535202 DOI: 10.1016/j.bbapap.2013.03.007  1
2013 Bastidas AC, Deal MS, Steichen JM, Guo Y, Wu J, Taylor SS. Phosphoryl transfer by protein kinase A is captured in a crystal lattice. Journal of the American Chemical Society. 135: 4788-98. PMID 23458248 DOI: 10.1021/ja312237q  1
2013 Sastri M, Haushalter KJ, Panneerselvam M, Chang P, Fridolfsson H, Finley JC, Ng D, Schilling JM, Miyanohara A, Day ME, Hakozaki H, Petrosyan S, Koller A, King CC, Darshi M, ... ... Taylor SS, et al. A kinase interacting protein (AKIP1) is a key regulator of cardiac stress. Proceedings of the National Academy of Sciences of the United States of America. 110: E387-96. PMID 23319652 DOI: 10.1073/pnas.1221670110  1
2012 Cembran A, Masterson LR, McClendon CL, Taylor SS, Gao J, Veglia G. Conformational equilibrium of N-myristoylated cAMP-dependent protein kinase A by molecular dynamics simulations. Biochemistry. 51: 10186-96. PMID 23205665 DOI: 10.1021/bi301279f  1
2012 Burgers PP, Ma Y, Margarucci L, Mackey M, van der Heyden MA, Ellisman M, Scholten A, Taylor SS, Heck AJ. A small novel A-kinase anchoring protein (AKAP) that localizes specifically protein kinase A-regulatory subunit I (PKA-RI) to the plasma membrane. The Journal of Biological Chemistry. 287: 43789-97. PMID 23115245 DOI: 10.1074/jbc.M112.395970  1
2012 Guo Y, Wilderman A, Zhang L, Taylor SS, Insel PA. Quantitative proteomics analysis of the cAMP/protein kinase A signaling pathway. Biochemistry. 51: 9323-32. PMID 23110364 DOI: 10.1021/bi301282k  1
2012 Darshi M, Trinh KN, Murphy AN, Taylor SS. Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space. The Journal of Biological Chemistry. 287: 39480-91. PMID 23019327 DOI: 10.1074/jbc.M112.387696  1
2012 Taylor SS, Ilouz R, Zhang P, Kornev AP. Assembly of allosteric macromolecular switches: lessons from PKA. Nature Reviews. Molecular Cell Biology. 13: 646-58. PMID 22992589 DOI: 10.1038/nrm3432  1
2012 Taylor SS, Keshwani MM, Steichen JM, Kornev AP. Evolution of the eukaryotic protein kinases as dynamic molecular switches. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 2517-28. PMID 22889904 DOI: 10.1098/rstb.2012.0054  1
2012 Ilouz R, Bubis J, Wu J, Yim YY, Deal MS, Kornev AP, Ma Y, Blumenthal DK, Taylor SS. Localization and quaternary structure of the PKA RIβ holoenzyme. Proceedings of the National Academy of Sciences of the United States of America. 109: 12443-8. PMID 22797896 DOI: 10.1073/pnas.1209538109  1
2012 Haste NM, Talabani H, Doo A, Merckx A, Langsley G, Taylor SS. Exploring the Plasmodium falciparum cyclic-adenosine monophosphate (cAMP)-dependent protein kinase (PfPKA) as a therapeutic target. Microbes and Infection / Institut Pasteur. 14: 838-50. PMID 22626931 DOI: 10.1016/j.micinf.2012.05.004  1
2012 Bastidas AC, Deal MS, Steichen JM, Keshwani MM, Guo Y, Taylor SS. Role of N-terminal myristylation in the structure and regulation of cAMP-dependent protein kinase. Journal of Molecular Biology. 422: 215-29. PMID 22617327 DOI: 10.1016/j.jmb.2012.05.021  1
2012 Keshwani MM, Klammt C, von Daake S, Ma Y, Kornev AP, Choe S, Insel PA, Taylor SS. Cotranslational cis-phosphorylation of the COOH-terminal tail is a key priming step in the maturation of cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 109: E1221-9. PMID 22493239 DOI: 10.1073/pnas.1202741109  1
2012 Steichen JM, Kuchinskas M, Keshwani MM, Yang J, Adams JA, Taylor SS. Structural basis for the regulation of protein kinase A by activation loop phosphorylation. The Journal of Biological Chemistry. 287: 14672-80. PMID 22334660 DOI: 10.1074/jbc.M111.335091  1
2012 Zhang P, Smith-Nguyen EV, Keshwani MM, Deal MS, Kornev AP, Taylor SS. Structure and allostery of the PKA RIIβ tetrameric holoenzyme. Science (New York, N.Y.). 335: 712-6. PMID 22323819 DOI: 10.1126/science.1213979  1
2012 Abrahamsen H, O'Neill AK, Kannan N, Kruse N, Taylor SS, Jennings PA, Newton AC. Peptidyl-prolyl isomerase Pin1 controls down-regulation of conventional protein kinase C isozymes. The Journal of Biological Chemistry. 287: 13262-78. PMID 22318721 DOI: 10.1074/jbc.M112.349753  1
2012 Yang J, Wu J, Steichen JM, Kornev AP, Deal MS, Li S, Sankaran B, Woods VL, Taylor SS. A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold. Journal of Molecular Biology. 415: 666-79. PMID 22138346 DOI: 10.1016/j.jmb.2011.11.035  1
2011 Means CK, Lygren B, Langeberg LK, Jain A, Dixon RE, Vega AL, Gold MG, Petrosyan S, Taylor SS, Murphy AN, Ha T, Santana LF, Tasken K, Scott JD. An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria. Proceedings of the National Academy of Sciences of the United States of America. 108: E1227-35. PMID 22084075 DOI: 10.1073/pnas.1107182108  1
2011 Osborne BW, Wu J, McFarland CJ, Nickl CK, Sankaran B, Casteel DE, Woods VL, Kornev AP, Taylor SS, Dostmann WR. Crystal structure of cGMP-dependent protein kinase reveals novel site of interchain communication. Structure (London, England : 1993). 19: 1317-27. PMID 21893290 DOI: 10.1016/j.str.2011.06.012  1
2011 Keshwani MM, von Daake S, Newton AC, Harris TK, Taylor SS. Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1). The Journal of Biological Chemistry. 286: 23552-8. PMID 21561857 DOI: 10.1074/jbc.M111.258004  0.56
2011 King CC, Sastri M, Chang P, Pennypacker J, Taylor SS. The rate of NF-κB nuclear translocation is regulated by PKA and A kinase interacting protein 1. Plos One. 6: e18713. PMID 21556136 DOI: 10.1371/journal.pone.0018713  1
2011 Day ME, Gaietta GM, Sastri M, Koller A, Mackey MR, Scott JD, Perkins GA, Ellisman MH, Taylor SS. Isoform-specific targeting of PKA to multivesicular bodies. The Journal of Cell Biology. 193: 347-63. PMID 21502359 DOI: 10.1083/jcb.201010034  1
2011 Masterson LR, Shi L, Metcalfe E, Gao J, Taylor SS, Veglia G. Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 108: 6969-74. PMID 21471451 DOI: 10.1073/pnas.1102701108  1
2011 Hu J, Yu H, Kornev AP, Zhao J, Filbert EL, Taylor SS, Shaw AS. Mutation that blocks ATP binding creates a pseudokinase stabilizing the scaffolding function of kinase suppressor of Ras, CRAF and BRAF. Proceedings of the National Academy of Sciences of the United States of America. 108: 6067-72. PMID 21441104 DOI: 10.1073/pnas.1102554108  1
2011 Boettcher AJ, Wu J, Kim C, Yang J, Bruystens J, Cheung N, Pennypacker JK, Blumenthal DA, Kornev AP, Taylor SS. Realizing the allosteric potential of the tetrameric protein kinase A RIα holoenzyme. Structure (London, England : 1993). 19: 265-76. PMID 21300294 DOI: 10.1016/j.str.2010.12.005  0.72
2011 McLaughlin WA, Hou T, Taylor SS, Wang W. The identification of novel cyclic AMP-dependent protein kinase anchoring proteins using bioinformatic filters and peptide arrays. Protein Engineering, Design & Selection : Peds. 24: 333-9. PMID 21115539 DOI: 10.1093/protein/gzq106  1
2011 Badireddy S, Yunfeng G, Ritchie M, Akamine P, Wu J, Kim CW, Taylor SS, Qingsong L, Swaminathan K, Anand GS. Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: conformational selection highlights a new concept in allosteric inhibitor design. Molecular & Cellular Proteomics : McP. 10: M110.004390. PMID 21081668 DOI: 10.1074/mcp.M110.004390  1
2011 Darshi M, Mendiola VL, Mackey MR, Murphy AN, Koller A, Perkins GA, Ellisman MH, Taylor SS. ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function. The Journal of Biological Chemistry. 286: 2918-32. PMID 21081504 DOI: 10.1074/jbc.M110.171975  1
2011 Taylor SS, Kornev AP. Protein kinases: evolution of dynamic regulatory proteins. Trends in Biochemical Sciences. 36: 65-77. PMID 20971646 DOI: 10.1016/j.tibs.2010.09.006  1
2010 Rinaldi J, Wu J, Yang J, Ralston CY, Sankaran B, Moreno S, Taylor SS. Structure of yeast regulatory subunit: a glimpse into the evolution of PKA signaling. Structure (London, England : 1993). 18: 1471-82. PMID 21070946 DOI: 10.1016/j.str.2010.08.013  1
2010 Masterson LR, Cheng C, Yu T, Tonelli M, Kornev A, Taylor SS, Veglia G. Dynamics connect substrate recognition to catalysis in protein kinase A. Nature Chemical Biology. 6: 821-8. PMID 20890288 DOI: 10.1038/nchembio.452  1
2010 Patel HH, Hamuro LL, Chun BJ, Kawaraguchi Y, Quick A, Rebolledo B, Pennypacker J, Thurston J, Rodriguez-Pinto N, Self C, Olson G, Insel PA, Giles WR, Taylor SS, Roth DM. Disruption of protein kinase A localization using a trans-activator of transcription (TAT)-conjugated A-kinase-anchoring peptide reduces cardiac function. The Journal of Biological Chemistry. 285: 27632-40. PMID 20581396 DOI: 10.1074/jbc.M110.146589  1
2010 Sjoberg TJ, Kornev AP, Taylor SS. Dissecting the cAMP-inducible allosteric switch in protein kinase A RIalpha. Protein Science : a Publication of the Protein Society. 19: 1213-21. PMID 20512974 DOI: 10.1002/pro.400  1
2010 Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, ... ... Taylor SS, et al. Climate change and the integrity of science. Science (New York, N.Y.). 328: 689-90. PMID 20448167 DOI: 10.1126/science.328.5979.689  0.52
2010 Taylor SS, Kornev AP. Yet another "active" pseudokinase, Erb3. Proceedings of the National Academy of Sciences of the United States of America. 107: 8047-8. PMID 20421461 DOI: 10.1073/pnas.1003436107  1
2010 McNicholl ET, Das R, SilDas S, Taylor SS, Melacini G. Communication between tandem cAMP binding domains in the regulatory subunit of protein kinase A-Ialpha as revealed by domain-silencing mutations. The Journal of Biological Chemistry. 285: 15523-37. PMID 20202931 DOI: 10.1074/jbc.M110.105783  1
2010 Anand GS, Krishnamurthy S, Bishnoi T, Kornev A, Taylor SS, Johnson DA. Cyclic AMP- and (Rp)-cAMPS-induced conformational changes in a complex of the catalytic and regulatory (RI{alpha}) subunits of cyclic AMP-dependent protein kinase. Molecular & Cellular Proteomics : McP. 9: 2225-37. PMID 20167947 DOI: 10.1074/mcp.M900388-MCP200  1
2010 Sarma GN, Kinderman FS, Kim C, von Daake S, Chen L, Wang BC, Taylor SS. Structure of D-AKAP2:PKA RI complex: insights into AKAP specificity and selectivity. Structure (London, England : 1993). 18: 155-66. PMID 20159461 DOI: 10.1016/j.str.2009.12.012  1
2010 Steichen JM, Iyer GH, Li S, Saldanha SA, Deal MS, Woods VL, Taylor SS. Global consequences of activation loop phosphorylation on protein kinase A. The Journal of Biological Chemistry. 285: 3825-32. PMID 19965870 DOI: 10.1074/jbc.M109.061820  1
2010 Kornev AP, Taylor SS. Defining the conserved internal architecture of a protein kinase. Biochimica Et Biophysica Acta. 1804: 440-4. PMID 19879387 DOI: 10.1016/j.bbapap.2009.10.017  1
2009 Khavrutskii IV, Grant B, Taylor SS, McCammon JA. A transition path ensemble study reveals a linchpin role for Mg(2+) during rate-limiting ADP release from protein kinase A. Biochemistry. 48: 11532-45. PMID 19886670 DOI: 10.1021/bi901475g  0.68
2009 Cheng CY, Yang J, Taylor SS, Blumenthal DK. Sensing domain dynamics in protein kinase A-I{alpha} complexes by solution X-ray scattering. The Journal of Biological Chemistry. 284: 35916-25. PMID 19837668 DOI: 10.1074/jbc.M109.059493  0.4
2009 Eggers CT, Schafer JC, Goldenring JR, Taylor SS. D-AKAP2 interacts with Rab4 and Rab11 through its RGS domains and regulates transferrin receptor recycling. The Journal of Biological Chemistry. 284: 32869-80. PMID 19797056 DOI: 10.1074/jbc.M109.022582  1
2009 Brown SH, Wu J, Kim C, Alberto K, Taylor SS. Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures. Journal of Molecular Biology. 393: 1070-82. PMID 19748511 DOI: 10.1016/j.jmb.2009.09.014  0.44
2009 Thompson EE, Kornev AP, Kannan N, Kim C, Ten Eyck LF, Taylor SS. Comparative surface geometry of the protein kinase family. Protein Science : a Publication of the Protein Society. 18: 2016-26. PMID 19610074 DOI: 10.1002/pro.209  0.72
2009 Romano RA, Kannan N, Kornev AP, Allison CJ, Taylor SS. A chimeric mechanism for polyvalent trans-phosphorylation of PKA by PDK1. Protein Science : a Publication of the Protein Society. 18: 1486-97. PMID 19530248 DOI: 10.1002/pro.146  0.72
2009 Kennedy EJ, Yang J, Pillus L, Taylor SS, Ghosh G. Identifying critical non-catalytic residues that modulate protein kinase A activity. Plos One. 4: e4746. PMID 19270744 DOI: 10.1371/journal.pone.0004746  1
2009 Kornev AP, Taylor SS. Pseudokinases: functional insights gleaned from structure. Structure (London, England : 1993). 17: 5-7. PMID 19141276 DOI: 10.1016/j.str.2008.12.005  1
2009 Yang J, Kennedy EJ, Wu J, Deal MS, Pennypacker J, Ghosh G, Taylor SS. Contribution of non-catalytic core residues to activity and regulation in protein kinase A. The Journal of Biological Chemistry. 284: 6241-8. PMID 19122195 DOI: 10.1074/jbc.M805862200  1
2009 Gould CM, Kannan N, Taylor SS, Newton AC. The chaperones Hsp90 and Cdc37 mediate the maturation and stabilization of protein kinase C through a conserved PXXP motif in the C-terminal tail. The Journal of Biological Chemistry. 284: 4921-35. PMID 19091746 DOI: 10.1074/jbc.M808436200  1
2008 Kornev AP, Taylor SS, Ten Eyck LF. A helix scaffold for the assembly of active protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 105: 14377-82. PMID 18787129 DOI: 10.1073/pnas.0807988105  0.72
2008 Torkamani A, Kannan N, Taylor SS, Schork NJ. Congenital disease SNPs target lineage specific structural elements in protein kinases. Proceedings of the National Academy of Sciences of the United States of America. 105: 9011-6. PMID 18579784 DOI: 10.1073/pnas.0802403105  1
2008 Kannan N, Taylor SS. Rethinking pseudokinases. Cell. 133: 204-5. PMID 18423189 DOI: 10.1016/j.cell.2008.04.005  1
2008 Kornev AP, Taylor SS, Ten Eyck LF. A generalized allosteric mechanism for cis-regulated cyclic nucleotide binding domains. Plos Computational Biology. 4: e1000056. PMID 18404204 DOI: 10.1371/journal.pcbi.1000056  0.72
2008 Ma Y, Taylor SS. A molecular switch for targeting between endoplasmic reticulum (ER) and mitochondria: conversion of a mitochondria-targeting element into an ER-targeting signal in DAKAP1. The Journal of Biological Chemistry. 283: 11743-51. PMID 18287098 DOI: 10.1074/jbc.M710494200  1
2008 Masterson LR, Mascioni A, Traaseth NJ, Taylor SS, Veglia G. Allosteric cooperativity in protein kinase A. Proceedings of the National Academy of Sciences of the United States of America. 105: 506-11. PMID 18178622 DOI: 10.1073/pnas.0709214104  1
2008 Ten Eyck LF, Taylor SS, Kornev AP. Conserved spatial patterns across the protein kinase family. Biochimica Et Biophysica Acta. 1784: 238-43. PMID 18067871 DOI: 10.1016/j.bbapap.2007.11.002  0.72
2008 Taylor SS, Kim C, Cheng CY, Brown SH, Wu J, Kannan N. Signaling through cAMP and cAMP-dependent protein kinase: diverse strategies for drug design. Biochimica Et Biophysica Acta. 1784: 16-26. PMID 17996741 DOI: 10.1016/j.bbapap.2007.10.002  0.44
2008 Kannan N, Neuwald AF, Taylor SS. Analogous regulatory sites within the alphaC-beta4 loop regions of ZAP-70 tyrosine kinase and AGC kinases. Biochimica Et Biophysica Acta. 1784: 27-32. PMID 17977811 DOI: 10.1016/j.bbapap.2007.09.007  1
2007 Kannan N, Wu J, Anand GS, Yooseph S, Neuwald AF, Venter JC, Taylor SS. Evolution of allostery in the cyclic nucleotide binding module. Genome Biology. 8: R264. PMID 18076763 DOI: 10.1186/gb-2007-8-12-r264  1
2007 Valiev M, Yang J, Adams JA, Taylor SS, Weare JH. Phosphorylation reaction in cAPK protein kinase-free energy quantum mechanical/molecular mechanics simulations. The Journal of Physical Chemistry. B. 111: 13455-64. PMID 17983217 DOI: 10.1021/jp074853q  1
2007 Anand GS, Hotchko M, Brown SH, Ten Eyck LF, Komives EA, Taylor SS. R-subunit isoform specificity in protein kinase A: distinct features of protein interfaces in PKA types I and II by amide H/2H exchange mass spectrometry. Journal of Molecular Biology. 374: 487-99. PMID 17942118 DOI: 10.1016/j.jmb.2007.09.035  1
2007 Wu J, Brown SH, von Daake S, Taylor SS. PKA type IIalpha holoenzyme reveals a combinatorial strategy for isoform diversity. Science (New York, N.Y.). 318: 274-9. PMID 17932298 DOI: 10.1126/science.1146447  0.32
2007 Alto NM, Weflen AW, Rardin MJ, Yarar D, Lazar CS, Tonikian R, Koller A, Taylor SS, Boone C, Sidhu SS, Schmid SL, Hecht GA, Dixon JE. The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways. The Journal of Cell Biology. 178: 1265-78. PMID 17893247 DOI: 10.1083/jcb.200705021  1
2007 Kim C, Cheng CY, Saldanha SA, Taylor SS. PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation. Cell. 130: 1032-43. PMID 17889648 DOI: 10.1016/j.cell.2007.07.018  0.44
2007 Martin BR, Deerinck TJ, Ellisman MH, Taylor SS, Tsien RY. Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1alpha-mediated localization in living cells. Chemistry & Biology. 14: 1031-42. PMID 17884635 DOI: 10.1016/j.chembiol.2007.07.017  1
2007 Anand G, Taylor SS, Johnson DA. Cyclic-AMP and pseudosubstrate effects on type-I A-kinase regulatory and catalytic subunit binding kinetics. Biochemistry. 46: 9283-91. PMID 17658893 DOI: 10.1021/bi700421h  1
2007 Humphries KM, Pennypacker JK, Taylor SS. Redox regulation of cAMP-dependent protein kinase signaling: kinase versus phosphatase inactivation. The Journal of Biological Chemistry. 282: 22072-9. PMID 17548350 DOI: 10.1074/jbc.M702582200  1
2007 Lim CJ, Han J, Yousefi N, Ma Y, Amieux PS, McKnight GS, Taylor SS, Ginsberg MH. Alpha4 integrins are type I cAMP-dependent protein kinase-anchoring proteins. Nature Cell Biology. 9: 415-21. PMID 17369818 DOI: 10.1038/ncb1561  1
2007 Kannan N, Taylor SS, Zhai Y, Venter JC, Manning G. Structural and functional diversity of the microbial kinome. Plos Biology. 5: e17. PMID 17355172 DOI: 10.1371/journal.pbio.0050017  1
2007 Yooseph S, Sutton G, Rusch DB, Halpern AL, Williamson SJ, Remington K, Eisen JA, Heidelberg KB, Manning G, Li W, Jaroszewski L, Cieplak P, Miller CS, Li H, Mashiyama ST, ... ... Taylor SS, et al. The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families. Plos Biology. 5: e16. PMID 17355171 DOI: 10.1371/journal.pbio.0050016  1
2007 Schauble S, King CC, Darshi M, Koller A, Shah K, Taylor SS. Identification of ChChd3 as a novel substrate of the cAMP-dependent protein kinase (PKA) using an analog-sensitive catalytic subunit. The Journal of Biological Chemistry. 282: 14952-9. PMID 17242405 DOI: 10.1074/jbc.M609221200  1
2007 Kannan N, Haste N, Taylor SS, Neuwald AF. The hallmark of AGC kinase functional divergence is its C-terminal tail, a cis-acting regulatory module. Proceedings of the National Academy of Sciences of the United States of America. 104: 1272-7. PMID 17227859 DOI: 10.1073/pnas.0610251104  0.32
2007 Das R, Esposito V, Abu-Abed M, Anand GS, Taylor SS, Melacini G. cAMP activation of PKA defines an ancient signaling mechanism Proceedings of the National Academy of Sciences of the United States of America. 104: 93-98. PMID 17182741 DOI: 10.1073/pnas.0609033103  1
2006 Kornev AP, Haste NM, Taylor SS, Eyck LF. Surface comparison of active and inactive protein kinases identifies a conserved activation mechanism. Proceedings of the National Academy of Sciences of the United States of America. 103: 17783-8. PMID 17095602 DOI: 10.1073/pnas.0607656103  1
2006 Kinderman FS, Kim C, von Daake S, Ma Y, Pham BQ, Spraggon G, Xuong NH, Jennings PA, Taylor SS. A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase. Molecular Cell. 24: 397-408. PMID 17081990 DOI: 10.1016/j.molcel.2006.09.015  1
2006 Cranston AN, Carniti C, Oakhill K, Radzio-Andzelm E, Stone EA, McCallion AS, Hodgson S, Clarke S, Mondellini P, Leyland J, Pierotti MA, Whittaker J, Taylor SS, Bongarzone I, Ponder BA. RET is constitutively activated by novel tandem mutations that alter the active site resulting in multiple endocrine neoplasia type 2B. Cancer Research. 66: 10179-87. PMID 17047083 DOI: 10.1158/0008-5472.CAN-06-0884  1
2006 Esposito V, Sjoberg T, Das R, Brown S, Taylor SS, Melacini G. NMR assignment of the cAMP-binding domain A of the PKA regulatory subunit [62] Journal of Biomolecular Nmr. 36: 64. PMID 17016670 DOI: 10.1007/s10858-006-9050-9  1
2006 Kim C, Vigil D, Anand G, Taylor SS. Structure and dynamics of PKA signaling proteins. European Journal of Cell Biology. 85: 651-4. PMID 16647784 DOI: 10.1016/j.ejcb.2006.02.004  1
2006 Vigil D, Blumenthal DK, Taylor SS, Trewhella J. Solution scattering reveals large differences in the global structures of type II protein kinase A isoforms. Journal of Molecular Biology. 357: 880-9. PMID 16460759 DOI: 10.1016/j.jmb.2006.01.006  1
2006 Vigil D, Lin JH, Sotriffer CA, Pennypacker JK, McCammon JA, Taylor SS. A simple electrostatic switch important in the activation of type I protein kinase A by cyclic AMP. Protein Science : a Publication of the Protein Society. 15: 113-21. PMID 16322564 DOI: 10.1110/ps.051723606  0.68
2005 Taylor SS, Kim C, Vigil D, Haste NM, Yang J, Wu J, Anand GS. Dynamics of signaling by PKA. Biochimica Et Biophysica Acta. 1754: 25-37. PMID 16214430 DOI: 10.1016/j.bbapap.2005.08.024  1
2005 Vigil D, Blumenthal DK, Taylor SS, Trewhella J. The conformationally dynamic C helix of the RIalpha subunit of protein kinase A mediates isoform-specific domain reorganization upon C subunit binding. The Journal of Biological Chemistry. 280: 35521-7. PMID 16109722 DOI: 10.1074/jbc.M506769200  1
2005 Sastri M, Barraclough DM, Carmichael PT, Taylor SS. A-kinase-interacting protein localizes protein kinase A in the nucleus. Proceedings of the National Academy of Sciences of the United States of America. 102: 349-54. PMID 15630084 DOI: 10.1073/pnas.0408608102  1
2004 Vigil D, Blumenthal DK, Brown S, Taylor SS, Trewhella J. Differential effects of substrate on type I and type II PKA holoenzyme dissociation. Biochemistry. 43: 5629-36. PMID 15134437 DOI: 10.1021/bi0499157  1
2004 Vigil D, Blumenthal DK, Heller WT, Brown S, Canaves JM, Taylor SS, Trewhella J. Conformational differences among solution structures of the type Ialpha, IIalpha and IIbeta protein kinase A regulatory subunit homodimers: role of the linker regions. Journal of Molecular Biology. 337: 1183-94. PMID 15046986 DOI: 10.1016/j.jmb.2004.02.028  1
2004 Heller WT, Vigil D, Brown S, Blumenthal DK, Taylor SS, Trewhella J. C subunits binding to the protein kinase A RI alpha dimer induce a large conformational change. The Journal of Biological Chemistry. 279: 19084-90. PMID 14985329 DOI: 10.1074/jbc.M313405200  1
2004 Zawadzki KM, Taylor SS. cAMP-dependent protein kinase regulatory subunit type IIbeta: active site mutations define an isoform-specific network for allosteric signaling by cAMP. The Journal of Biological Chemistry. 279: 7029-36. PMID 14625280 DOI: 10.1074/jbc.M310804200  1
2003 Zawadzki KM, Hamuro Y, Kim JS, Garrod S, Stranz DD, Taylor SS, Woods VL. Dissecting interdomain communication within cAPK regulatory subunit type IIβ using enhanced amide hydrogen/deuterium exchange mass spectrometry (DXMS) Protein Science. 12: 1980-1990. PMID 12930997 DOI: 10.1110/ps.03166903  1
2003 Banky P, Roy M, Newlon MG, Morikis D, Haste NM, Taylor SS, Jennings PA. Related protein-protein interaction modules present drastically different surface topographies despite a conserved helical platform. Journal of Molecular Biology. 330: 1117-29. PMID 12860132 DOI: 10.1016/S0022-2836(03)00552-7  1
2003 Zawadzki KM, Pan CP, Barkley MD, Johnson D, Taylor SS. Endogenous tryptophan residues of cAPK regulatory subunit type IIbeta reveal local variations in environments and dynamics. Proteins. 51: 552-61. PMID 12784214 DOI: 10.1002/prot.10326  1
2003 Hamuro Y, Zawadzki KM, Kim JS, Stranz DD, Taylor SS, Woods VL. Dynamics of cAPK type IIbeta activation revealed by enhanced amide H/2H exchange mass spectrometry (DXMS). Journal of Molecular Biology. 327: 1065-76. PMID 12662931 DOI: 10.1016/S0022-2836(03)00234-1  1
2002 Taylor SS, Kim CW, Cheng CY, Kannan N, Sastri M, Eggers CW, Wu J. Fifty Years Since the Discovery of PKA. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 4123. PMID 29430987 DOI: 10.1096/fasebj.22.1_supplement.412.3  0.44
2001 Diller TC, Madhusudan, Xuong NH, Taylor SS. Molecular basis for regulatory subunit diversity in cAMP-dependent protein kinase: crystal structure of the type II beta regulatory subunit. Structure (London, England : 1993). 9: 73-82. PMID 11342137 DOI: 10.1016/S0969-2126(00)00556-6  1
2000 Diller TC, Xuong NH, Taylor SS. Type II beta regulatory subunit of cAMP-dependent protein kinase: purification strategies to optimize crystallization. Protein Expression and Purification. 20: 357-64. PMID 11087674 DOI: 10.1006/prep.2000.1312  1
2000 Banky P, Newlon MG, Roy M, Garrod S, Taylor SS, Jennings PA. Isoform-specific differences between the type Iα and IIα cyclic AMP-dependent protein kinase anchoring domains revealed by solution NMR Journal of Biological Chemistry. 275: 35146-35152. PMID 10899163 DOI: 10.1074/jbc.M003961200  1
2000 Cheesman EJ, Sharp RJ, Zlot CH, Liu CY, Taylor S, Marcovina SM, Young SG, McCormick SP. An analysis of the interaction between mouse apolipoprotein B100 and apolipoprotein(a). The Journal of Biological Chemistry. 275: 28195-200. PMID 10837476 DOI: 10.1074/jbc.M002772200  1
1999 Setyawan J, Koide K, Diller TC, Bunnage ME, Taylor SS, Nicolaou KC, Brunton LL. Inhibition of protein kinases by balanol: specificity within the serine/threonine protein kinase subfamily. Molecular Pharmacology. 56: 370-6. PMID 10419556  1
1999 Narayana N, Diller TC, Koide K, Bunnage ME, Nicolaou KC, Brunton LL, Xuong NH, Ten Eyck LF, Taylor SS. Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase. Biochemistry. 38: 2367-76. PMID 10029530 DOI: 10.1021/bi9820659  1
1998 Banky P, Huang LJ, Taylor SS. Dimerization/docking domain of the type Ialpha regulatory subunit of cAMP-dependent protein kinase. Requirements for dimerization and docking are distinct but overlapping. The Journal of Biological Chemistry. 273: 35048-55. PMID 9857038 DOI: 10.1074/jbc.273.52.35048  1
1998 Borén J, Lee I, Zhu W, Arnold K, Taylor S, Innerarity TL. Identification of the low density lipoprotein receptor-binding site in apolipoprotein B100 and the modulation of its binding activity by the carboxyl terminus in familial defective Apo-B100 Journal of Clinical Investigation. 101: 1084-1093. PMID 9486979  1
1997 Allan CM, Taylor S, Taylor JM. Two hepatic enhancers, HCR.1 and HCR.2, coordinate the liver expression of the entire human apolipoprotein E/C-I/C-IV/C-II gene cluster. The Journal of Biological Chemistry. 272: 29113-9. PMID 9360987 DOI: 10.1074/jbc.272.46.29113  1
1997 León DA, Herberg FW, Banky P, Taylor SS. A stable alpha-helical domain at the N terminus of the RIalpha subunits of cAMP-dependent protein kinase is a novel dimerization/docking motif. The Journal of Biological Chemistry. 272: 28431-7. PMID 9353302 DOI: 10.1074/jbc.272.45.28431  1
1997 McCormick SP, Ng JK, Cham CM, Taylor S, Marcovina SM, Segrest JP, Hammer RE, Young SG. Transgenic mice expressing human ApoB95 and ApoB97. Evidence that sequences within the carboxyl-terminal portion of human apoB100 are important for the assembly of lipoprotein. The Journal of Biological Chemistry. 272: 23616-22. PMID 9295301 DOI: 10.1074/jbc.272.38.23616  1
1994 Brooks AR, Nagy BP, Taylor S, Simonet WS, Taylor JM, Levy-Wilson B. Sequences containing the second-intron enhancer are essential for transcription of the human apolipoprotein B gene in the livers of transgenic mice. Molecular and Cellular Biology. 14: 2243-56. PMID 8139530  1
1988 First EA, Bubis J, Taylor SS. Subunit interaction sites between the regulatory and catalytic subunits of cAMP-dependent protein kinase. Identification of a specific interchain disulfide bond. The Journal of Biological Chemistry. 263: 5176-82. PMID 3356685  1
1988 Taylor SS, Bubis J, Toner-Webb J, Saraswat LD, First EA, Buechler JA, Knighton DR, Sowadski J. CAMP-dependent protein kinase: prototype for a family of enzymes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 2: 2677-85. PMID 3294077  1
1988 Bubis J, Neitzel JJ, Saraswat LD, Taylor SS. A point mutation abolishes binding of cAMP to site A in the regulatory subunit of cAMP-dependent protein kinase. The Journal of Biological Chemistry. 263: 9668-73. PMID 2898473  1
1988 Ringheim GE, Saraswat LD, Bubis J, Taylor SS. Deletion of cAMP-binding site B in the regulatory subunit of cAMP-dependent protein kinase alters the photoaffinity labeling of site A. The Journal of Biological Chemistry. 263: 18247-52. PMID 2848031  1
1988 Saraswat LD, Ringheim GE, Bubis J, Taylor SS. Deletion mutants as probes for localizing regions of subunit interaction in cAMP-dependent protein kinase. The Journal of Biological Chemistry. 263: 18241-6. PMID 2848030  1
1988 Bubis J, Saraswat LD, Taylor SS. Tyrosine-371 contributes to the positive cooperativity between the two cAMP binding sites in the regulatory subunit of cAMP-dependent protein kinase I. Biochemistry. 27: 1570-6. PMID 2835094  1
1987 Bubis J, Taylor SS. Limited proteolysis alters the photoaffinity labeling of adenosine 3',5'-monophosphate dependent protein kinase II with 8-azidoadenosine 3',5'-monophosphate. Biochemistry. 26: 5997-6004. PMID 3689756  1
1987 Bubis J, Vedvick TS, Taylor SS. Antiparallel alignment of the two protomers of the regulatory subunit dimer of cAMP-dependent protein kinase I. The Journal of Biological Chemistry. 262: 14961-6. PMID 3667618  1
1987 Weber IT, Steitz TA, Bubis J, Taylor SS. Predicted structures of cAMP binding domains of type I and II regulatory subunits of cAMP-dependent protein kinase. Biochemistry. 26: 343-51. PMID 3030405  1
1987 Bubis J, Taylor SS. Correlation of photolabeling with occupancy of cAMP binding sites in the regulatory subunit of cAMP-dependent protein kinase I. Biochemistry. 26: 3478-86. PMID 2820470  1
1986 Taylor SS, Saraswat LD, Toner JA, Bubis J. The relationship between structure and function in cAMP-dependent protein kinases. Annals of the New York Academy of Sciences. 478: 191-202. PMID 3026223  1
1985 Dothie JM, Giglio JR, Moore CB, Taylor SS, Hartley BS. Ribitol dehydrogenase of Klebsiella aerogenes. Sequence and properties of wild-type and mutant strains. The Biochemical Journal. 230: 569-78. PMID 3904726  1
1985 Bubis J, Taylor SS. Covalent modification of both cAMP binding sites in cAMP-dependent protein kinase I by 8-azidoadenosine 3',5'-monophosphate. Biochemistry. 24: 2163-70. PMID 2986689  1
1977 Taylor SS. Amino acid sequence of dogfish muscle lactate dehydrogenase Journal of Biological Chemistry. 252: 1799-1806. PMID 838743  1
1977 Eventoff W, Rossmann MG, Taylor SS, Torff HJ, Meyer H, Keil W, Kiltz HH. Structural adaptations of lactate dehydrogenase isozymes Proceedings of the National Academy of Sciences of the United States of America. 74: 2677-2681. PMID 197516 DOI: 10.1073/pnas.74.7.2677  1
1975 Taylor SS, Allison WS, Kaplan NO. The amino acid sequence of the tryptic peptides isolated from dogfish M4 lactate dehydrogenase. The Journal of Biological Chemistry. 250: 8740-7. PMID 1184589  1
1974 Taylor SS, Rigby PW, Hartley BS. Ribitol dehydrogenase from Klebsiella aerogenes. Purification and subunit structure. The Biochemical Journal. 141: 693-700. PMID 4618776  1
1974 Kaplan NO, Everse J, Dixon JE, Stolzenbach FE, Lee CY, Lee CL, Taylor SS, Mosbach K. Purification and separation of pyridine nucleotide-linked dehydrogenases by affinity chromatography techniques. Proceedings of the National Academy of Sciences of the United States of America. 71: 3450-4. PMID 4372619 DOI: 10.1073/pnas.71.9.3450  1
1973 Taylor SS, Oxley SS, Allison WS, Kaplan NO. Aminoacid sequence of dogfish M4 lactate dehydrogenase. Proceedings of the National Academy of Sciences of the United States of America. 70: 1790-3. PMID 4515938  1
1973 Adams MJ, Buehner M, Chandrasekhar K, Ford GC, Hackert ML, Liljas A, Rossmann MG, Smiley IE, Allison WS, Everse J, Kaplan NO, Taylor SS. Structure-function relationships in lactate dehydrogenase. Proceedings of the National Academy of Sciences of the United States of America. 70: 1968-72. PMID 4146647 DOI: 10.1073/pnas.70.7.1968  1
1969 Taylor SS, Heath EC. The incorporation of beta-hydroxy fatty acids into a phospholipid of Escherichia coli B. The Journal of Biological Chemistry. 244: 6605-16. PMID 4902888  1
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