| Year |
Citation |
Score |
| 2019 |
Chang D, Ahmad G, Nardozzi J, Sackton K, Lyons J, Sauer K, Andresen T, Jones D. Abstract 933: Surface-tethered IL-12 improves tumor-specific T-cell therapy and enhances inflammatory activity in tumors without inducing systemic toxicities Cancer Research. 79: 933-933. DOI: 10.1158/1538-7445.Sabcs18-933 |
0.308 |
|
| 2018 |
Elich M, Sauer K. Regulation of Hematopoietic Cell Development and Function Through Phosphoinositides. Frontiers in Immunology. 9: 931. PMID 29780388 DOI: 10.3389/Fimmu.2018.00931 |
0.447 |
|
| 2016 |
Westernberg L, Conche C, Huang YH, Rigaud S, Deng Y, Siegemund S, Mukherjee S, Nosaka L, Das J, Sauer K. Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent. Elife. 5. PMID 26880557 DOI: 10.7554/Elife.10786 |
0.415 |
|
| 2016 |
Westernberg L, Conche C, Huang YH, Rigaud S, Deng Y, Siegemund S, Mukherjee S, Nosaka L, Das J, Sauer K. Author response: Non-canonical antagonism of PI3K by the kinase Itpkb delays thymocyte β-selection and renders it Notch-dependent Elife. DOI: 10.7554/Elife.10786.018 |
0.313 |
|
| 2016 |
Sauer K, Conche C, Jin H, Bethel K, Rigaud S, Westernberg L, Siegemund S, Xiao C. Abstract LB-020: IP3 3-kinase B suppresses B-cell lymphoma by antagonizing PI3K/mTOR in B cells Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-020 |
0.413 |
|
| 2015 |
Yea K, Zhang H, Xie J, Jones TM, Lin CW, Francesconi W, Berton F, Fallahi M, Sauer K, Lerner RA. Agonist antibody that induces human malignant cells to kill one another. Proceedings of the National Academy of Sciences of the United States of America. PMID 26487683 DOI: 10.1073/Pnas.1519079112 |
0.367 |
|
| 2015 |
Sauer K, Okkenhaug K. Editorial: Lipid Signaling in T Cell Development and Function. Frontiers in Immunology. 6: 410. PMID 26322043 DOI: 10.3389/Fimmu.2015.00410 |
0.395 |
|
| 2015 |
Lawson BR, Gonzalez-Quintial R, Eleftheriadis T, Farrar MA, Miller SD, Sauer K, McGavern DB, Kono DH, Baccala R, Theofilopoulos AN. Interleukin-7 is required for CD4(+) T cell activation and autoimmune neuroinflammation. Clinical Immunology (Orlando, Fla.). 161: 260-269. PMID 26319414 DOI: 10.1016/J.Clim.2015.08.007 |
0.325 |
|
| 2015 |
Rigaud S, Sauer K. IP3 3-kinase B prevents bone marrow failure. Oncotarget. 6: 15706-7. PMID 26202960 DOI: 10.18632/Oncotarget.4480 |
0.423 |
|
| 2015 |
Siegemund S, Shepherd J, Xiao C, Sauer K. hCD2-iCre and Vav-iCre mediated gene recombination patterns in murine hematopoietic cells. Plos One. 10: e0124661. PMID 25884630 DOI: 10.1371/Journal.Pone.0124661 |
0.386 |
|
| 2015 |
Siegemund S, Rigaud S, Conche C, Broaten B, Schaffer L, Westernberg L, Head SR, Sauer K. IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice. Blood. 125: 2786-97. PMID 25788703 DOI: 10.1182/Blood-2014-06-583187 |
0.407 |
|
| 2014 |
Rybakin V, Westernberg L, Fu G, Kim HO, Ampudia J, Sauer K, Gascoigne NR. Allelic exclusion of TCR α-chains upon severe restriction of Vα repertoire. Plos One. 9: e114320. PMID 25500569 DOI: 10.1371/Journal.Pone.0114320 |
0.379 |
|
| 2014 |
Xu X, Jaeger ER, Wang X, Lagler-Ferrez E, Batalov S, Mathis NL, Wiltshire T, Walker JR, Cooke MP, Sauer K, Huang YH. Mst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migration. Plos One. 9: e105561. PMID 25133611 DOI: 10.1371/Journal.Pone.0105561 |
0.409 |
|
| 2014 |
Conche C, Sauer K. Uncovering the PI3Ksome: phosphoinositide 3-kinases and counteracting PTEN form a signaling complex with intrinsic regulatory properties. Molecular and Cellular Biology. 34: 3356-8. PMID 25047838 DOI: 10.1128/Mcb.00920-14 |
0.406 |
|
| 2013 |
Fu G, Casas J, Rigaud S, Rybakin V, Lambolez F, Brzostek J, Hoerter JA, Paster W, Acuto O, Cheroutre H, Sauer K, Gascoigne NR. Themis sets the signal threshold for positive and negative selection in T-cell development. Nature. 504: 441-5. PMID 24226767 DOI: 10.1038/Nature12718 |
0.353 |
|
| 2013 |
Mukherjee S, Rigaud S, Seok SC, Fu G, Prochenka A, Dworkin M, Gascoigne NR, Vieland VJ, Sauer K, Das J. In silico modeling of Itk activation kinetics in thymocytes suggests competing positive and negative IP4 mediated feedbacks increase robustness. Plos One. 8: e73937. PMID 24066087 DOI: 10.1371/Journal.Pone.0073937 |
0.363 |
|
| 2013 |
Sauer K, Park E, Siegemund S, French AR, Wahle JA, Sternberg L, Rigaud S, Jonsson AH, Yokoyama WM, Huang YH. Inositol tetrakisphosphate limits NK cell effector functions by controlling PI3K signaling. Blood. 121: 286-97. PMID 23175687 DOI: 10.1182/Blood-2012-05-429241 |
0.621 |
|
| 2012 |
Hirve N, Levytskyy RM, Rigaud S, Guimond DM, Zal T, Sauer K, Tsoukas CD. A conserved motif in the ITK PH-domain is required for phosphoinositide binding and TCR signaling but dispensable for adaptor protein interactions. Plos One. 7: e45158. PMID 23028816 DOI: 10.1371/Journal.Pone.0045158 |
0.393 |
|
| 2011 |
Fu G, Hu J, Niederberger-Magnenat N, Rybakin V, Casas J, Yachi PP, Feldstein S, Ma B, Hoerter JA, Ampudia J, Rigaud S, Lambolez F, Gavin AL, Sauer K, Cheroutre H, et al. Protein kinase C η is required for T cell activation and homeostatic proliferation. Science Signaling. 4: ra84. PMID 22155788 DOI: 10.1126/Scisignal.2002058 |
0.418 |
|
| 2011 |
Mukherjee S, Rigaud S, Sauer K, Das J. Competing Negative and Positive Feedback Generate Specific T Cell Responses by Tuning Duration and Amplitude of Itk Activation Biophysical Journal. 100: 1-8. DOI: 10.1016/J.Bpj.2010.12.1191 |
0.395 |
|
| 2010 |
Huang YH, Sauer K. Lipid signaling in T-cell development and function. Cold Spring Harbor Perspectives in Biology. 2: a002428. PMID 20943760 DOI: 10.1101/Cshperspect.A002428 |
0.409 |
|
| 2010 |
Sauer K, Cooke MP. Regulation of immune cell development through soluble inositol-1,3,4,5-tetrakisphosphate. Nature Reviews. Immunology. 10: 257-71. PMID 20336153 DOI: 10.1038/Nri2745 |
0.407 |
|
| 2010 |
Poderycki M, Tomimori Y, Ando T, Xiao W, Maeda-Yamamoto M, Sauer K, Kawakami Y, Kawakami T. A minor catalytic activity of Src family kinases is sufficient for maximal activation of mast cells via the high-affinity IgE receptor. Journal of Immunology (Baltimore, Md. : 1950). 184: 84-93. PMID 19949072 DOI: 10.4049/Jimmunol.0901590 |
0.463 |
|
| 2009 |
Sauer K, Huang YH, Lin H, Sandberg M, Mayr GW. Phosphoinositide and inositol phosphate analysis in lymphocyte activation. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit11.1. PMID 19918943 DOI: 10.1002/0471142735.Im1101S87 |
0.395 |
|
| 2009 |
Lenox LE, Kambayashi T, Okumura M, Prieto C, Sauer K, Bunte RM, Jordan MS, Koretzky GA, Nichols KE. Mutation of tyrosine 145 of lymphocyte cytosolic protein 2 protects mice from anaphylaxis and arthritis. The Journal of Allergy and Clinical Immunology. 124: 1088-98. PMID 19895996 DOI: 10.1016/J.Jaci.2009.08.038 |
0.365 |
|
| 2009 |
Tinoco R, Alcalde V, Yang Y, Sauer K, Zuniga EI. Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivo. Immunity. 31: 145-57. PMID 19604493 DOI: 10.1016/J.Immuni.2009.06.015 |
0.325 |
|
| 2009 |
Fu G, Vallée S, Rybakin V, McGuire MV, Ampudia J, Brockmeyer C, Salek M, Fallen PR, Hoerter JA, Munshi A, Huang YH, Hu J, Fox HS, Sauer K, Acuto O, et al. Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling. Nature Immunology. 10: 848-56. PMID 19597499 DOI: 10.1038/Ni.1766 |
0.423 |
|
| 2009 |
Elsaesser H, Sauer K, Brooks DG. IL-21 is required to control chronic viral infection. Science (New York, N.Y.). 324: 1569-72. PMID 19423777 DOI: 10.1126/Science.1174182 |
0.311 |
|
| 2009 |
Barouch-Bentov R, Che J, Lee CC, Yang Y, Herman A, Jia Y, Velentza A, Watson J, Sternberg L, Kim S, Ziaee N, Miller A, Jackson C, Fujimoto M, Young M, ... ... Sauer K, et al. A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function. Molecular Cell. 33: 43-52. PMID 19150426 DOI: 10.1016/J.Molcel.2008.12.024 |
0.629 |
|
| 2007 |
Miller AT, Sandberg M, Huang YH, Young M, Sutton S, Sauer K, Cooke MP. Production of Ins(1,3,4,5)P4 mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation. Nature Immunology. 8: 514-21. PMID 17417640 DOI: 10.1038/Ni1458 |
0.315 |
|
| 2007 |
Huang YH, Grasis JA, Miller AT, Xu R, Soonthornvacharin S, Andreotti AH, Tsoukas CD, Cooke MP, Sauer K. Positive regulation of Itk PH domain function by soluble IP4. Science (New York, N.Y.). 316: 886-9. PMID 17412921 DOI: 10.1126/Science.1138684 |
0.362 |
|
| 2006 |
barouch-Bentov R, Sungjoon AHK, Velentza A, Ziaee N, Lee C, Liu Y, Cooke M, Sauer K. F.88. Using Forward Genetics to Identify Regulators of Autoimmunity: Altered B-Cell Function and Glomerulonephritis in the Lyn Mutant Weeb Clinical Immunology. 119. DOI: 10.1016/J.Clim.2006.04.128 |
0.334 |
|
| 2005 |
Chamberlain PP, Sandberg ML, Sauer K, Cooke MP, Lesley SA, Spraggon G. Structural insights into enzyme regulation for inositol 1,4,5-trisphosphate 3-kinase B. Biochemistry. 44: 14486-93. PMID 16262249 DOI: 10.1021/Bi051256Q |
0.333 |
|
| 2004 |
Wen BG, Pletcher MT, Warashina M, Choe SH, Ziaee N, Wiltshire T, Sauer K, Cooke MP. Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activity. Proceedings of the National Academy of Sciences of the United States of America. 101: 5604-9. PMID 15064401 DOI: 10.1073/Pnas.0306907101 |
0.412 |
|
| 2003 |
Salomon AR, Ficarro SB, Brill LM, Brinker A, Phung QT, Ericson C, Sauer K, Brock A, Horn DM, Schultz PG, Peters EC. Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 100: 443-8. PMID 12522270 DOI: 10.1073/Pnas.2436191100 |
0.418 |
|
| 2003 |
Takaki S, Tezuka Y, Sauer K, Kubo C, Kwon SM, Armstead E, Nakao K, Katsuki M, Perlmutter RM, Takatsu K. Impaired lymphopoiesis and altered B cell subpopulations in mice overexpressing Lnk adaptor protein. Journal of Immunology (Baltimore, Md. : 1950). 170: 703-10. PMID 12517931 DOI: 10.4049/Jimmunol.170.2.703 |
0.414 |
|
| 2001 |
Sauer K, Liou J, Singh SB, Yablonski D, Weiss A, Perlmutter RM. Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes. The Journal of Biological Chemistry. 276: 45207-16. PMID 11487585 DOI: 10.1074/Jbc.M106811200 |
0.464 |
|
| 2001 |
Lehner CF, Jacobs HW, Sauer K, Meyer CA. Regulation of the embryonic cell proliferation by Drosophila cyclin D and cyclin E complexes. Novartis Foundation Symposium. 237: 43-54; discussion 54. PMID 11444049 DOI: 10.1002/0470846666.Ch5 |
0.668 |
|
| 2000 |
Takaki S, Sauer K, Iritani BM, Chien S, Ebihara Y, Tsuji Ki, Takatsu K, Perlmutter RM. Control of B cell production by the adaptor protein Lnk: Definition of a conserved family of signal-modulating proteins Immunity. 13: 599-609. PMID 11114373 DOI: 10.1016/S1074-7613(00)00060-1 |
0.385 |
|
| 1998 |
Farrar MA, Doerfler P, Sauer K. Signal transduction pathways regulating the development of αβ T cells Biochimica Et Biophysica Acta - Reviews On Cancer. 1377: F35-F78. PMID 9659403 DOI: 10.1016/S0304-419X(97)00038-3 |
0.379 |
|
| 1996 |
Lane ME, Sauer K, Wallace K, Jan YN, Lehner CF, Vaessin H. Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell. 87: 1225-35. PMID 8980229 DOI: 10.1016/S0092-8674(00)81818-8 |
0.689 |
|
| 1996 |
Sauer K, Weigmann K, Sigrist S, Lehner CF. Novel members of the cdc2-related kinase family in Drosophila: cdk4/6, cdk5, PFTAIRE, and PITSLRE kinase. Molecular Biology of the Cell. 7: 1759-69. PMID 8930898 DOI: 10.1091/Mbc.7.11.1759 |
0.687 |
|
| 1995 |
Sauer K, Lehner CF. The role of cyclin E in the regulation of entry into S phase. Progress in Cell Cycle Research. 1: 125-39. PMID 9552358 DOI: 10.1007/978-1-4615-1809-9_10 |
0.662 |
|
| 1995 |
Sauer K, Knoblich JA, Richardson H, Lehner CF. Distinct modes of cyclin E/cdc2c kinase regulation and S-phase control in mitotic and endoreduplication cycles of Drosophila embryogenesis. Genes & Development. 9: 1327-39. PMID 7797073 DOI: 10.1101/Gad.9.11.1327 |
0.727 |
|
| 1994 |
Knoblich JA, Sauer K, Jones L, Richardson H, Saint R, Lehner CF. Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell. 77: 107-20. PMID 8156587 DOI: 10.1016/0092-8674(94)90239-9 |
0.729 |
|
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