Ke Ren - Publications

Affiliations: 
University of Maryland, College Park, College Park, MD 
Area:
pain, trigeminal

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Bushnell MC, Ren K, Sessle BJ. In memoriam. Ronald Dubner: 1934 to 2023. Pain. PMID 37433177 DOI: 10.1097/j.pain.0000000000002983  0.331
2019 Guo W, Imai S, Zou S, Yang J, Watanabe M, Wang J, Dubner R, Wei F, Ren K. Altered glial glutamate transporter expression in descending circuitry and the emergence of pain chronicity. Molecular Pain. 15: 1744806918825044. PMID 30799685 DOI: 10.1177/1744806918825044  0.79
2019 Guo W, Zou S, Mohammad Z, Wang S, Yang J, Li H, Dubner R, Wei F, Chung MK, Ro JY, Ren K. Voluntary biting behavior as a functional measure of orofacial pain in mice. Physiology & Behavior. PMID 30797813 DOI: 10.1016/j.physbeh.2019.02.024  0.665
2018 Guo W, Imai S, Yang JL, Zou S, Li H, Xu H, Moudgil KD, Dubner R, Wei F, Ren K. NF-KappaB Pathway Is Involved in Bone Marrow Stromal Cell-Produced Pain Relief. Frontiers in Integrative Neuroscience. 12: 49. PMID 30459569 DOI: 10.3389/Fnint.2018.00049  0.73
2017 Zhang Y, Li A, Xin J, Ren K, Berman BM, Lao L, Zhang RX. Electroacupuncture alleviates chemotherapy-induced pain through inhibiting phosphorylation of spinal CaMKII in rats. European Journal of Pain (London, England). PMID 29034548 DOI: 10.1002/ejp.1132  0.441
2017 Guo W, Imai S, Yang JL, Zou S, Watanabe M, Chu YX, Mohammad Z, Xu H, Moudgil KD, Wei F, Dubner R, Ren K. In vivo immune interactions of multipotent stromal cells underlie their long-lasting pain-relieving effect. Scientific Reports. 7: 10107. PMID 28860501 DOI: 10.1038/S41598-017-10251-Y  0.77
2016 Guo W, Chu YX, Imai S, Yang JL, Zou S, Mohammad Z, Wei F, Dubner R, Ren K. EXPRESS: Further observations on the behavioral and neural effects of bone marrow stromal cells in rodent pain models. Molecular Pain. 12. PMID 27329776 DOI: 10.1177/1744806916658043  0.704
2015 Ren K, Dubner R. Activity-triggered tetrapartite neuron-glial interactions following peripheral injury. Current Opinion in Pharmacology. 26: 16-25. PMID 26431645 DOI: 10.1016/j.coph.2015.09.006  0.619
2015 Bai G, Ren K, Dubner R. Epigenetic regulation of persistent pain. Translational Research : the Journal of Laboratory and Clinical Medicine. 165: 177-99. PMID 24948399 DOI: 10.1016/j.trsl.2014.05.012  0.6
2015 Zhang R, Seminowicz D, Ren K, Yuan X, Li M, Lao L, Berman B. Electroacupuncture modulates brain connectivity to alleviate osteoarthritis-associated pain in a rat model Integrative Medicine Research. 4: 5. DOI: 10.1016/J.Imr.2015.04.295  0.375
2014 Guo W, Miyoshi K, Dubner R, Gu M, Li M, Liu J, Yang J, Zou S, Ren K, Noguchi K, Wei F. Spinal 5-HT3 receptors mediate descending facilitation and contribute to behavioral hypersensitivity via a reciprocal neuron-glial signaling cascade. Molecular Pain. 10: 35. PMID 24913307 DOI: 10.1186/1744-8069-10-35  0.715
2014 Guo W, Imai S, Dubner R, Ren K. Multipotent stromal cells for arthritic joint pain therapy and beyond. Pain Management. 4: 153-62. PMID 24641438 DOI: 10.2217/pmt.14.1  0.625
2014 Kim YS, Chu Y, Han L, Li M, Li Z, Lavinka PC, Sun S, Tang Z, Park K, Caterina MJ, Ren K, Dubner R, Wei F, Dong X. Central terminal sensitization of TRPV1 by descending serotonergic facilitation modulates chronic pain. Neuron. 81: 873-87. PMID 24462040 DOI: 10.1016/J.Neuron.2013.12.011  0.699
2014 Zhang R, Lao L, Ren K, Berman BM. Mechanisms of acupuncture-electroacupuncture on persistent pain. Anesthesiology. 120: 482-503. PMID 24322588 DOI: 10.1097/ALN.0000000000000101  0.495
2014 Kim YS, Chu Y, Han L, Park K, Li M, Li Z, LaVinka P, Caterina MJ, Ren K, Dubner R, Wei F, Dong X. Imaging orofacial pain in mice Molecular Pain. 10: O2. DOI: 10.1186/1744-8069-10-S1-O2  0.691
2013 Zhang RX, Zhang M, Li A, Pan L, Berman BM, Ren K, Lao L. DAMGO in the central amygdala alleviates the affective dimension of pain in a rat model of inflammatory hyperalgesia. Neuroscience. 252: 359-66. PMID 23994597 DOI: 10.1016/j.neuroscience.2013.08.030  0.463
2013 Zhang RX, Ren K, Dubner R. Osteoarthritis pain mechanisms: basic studies in animal models. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 21: 1308-15. PMID 23973145 DOI: 10.1016/j.joca.2013.06.013  0.636
2013 Okubo M, Castro A, Guo W, Zou S, Ren K, Wei F, Keller A, Dubner R. Transition to persistent orofacial pain after nerve injury involves supraspinal serotonin mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5152-61. PMID 23516281 DOI: 10.1523/Jneurosci.3390-12.2013  0.702
2013 Meng X, Zhang Y, Lao L, Saito R, Li A, Bäckman CM, Berman BM, Ren K, Wei PK, Zhang RX. Spinal interleukin-17 promotes thermal hyperalgesia and NMDA NR1 phosphorylation in an inflammatory pain rat model. Pain. 154: 294-305. PMID 23246025 DOI: 10.1016/j.pain.2012.10.022  0.376
2013 Meng X, Lao L, Shen X, Berman BM, Ren K, Wei P, Zhang R. Electroacupuncture inhibits spinal interleukin-17A to alleviate inflammatory pain in a rat model The Open Pain Journal. 6: 183-189. DOI: 10.2174/1876386320130624001  0.367
2012 Chai B, Guo W, Wei F, Dubner R, Ren K. Trigeminal-rostral ventromedial medulla circuitry is involved in orofacial hyperalgesia contralateral to tissue injury. Molecular Pain. 8: 78. PMID 23092240 DOI: 10.1186/1744-8069-8-78  0.73
2012 Zhang Y, Zhang RX, Zhang M, Shen XY, Li A, Xin J, Ren K, Berman BM, Tan M, Lao L. Electroacupuncture inhibition of hyperalgesia in an inflammatory pain rat model: involvement of distinct spinal serotonin and norepinephrine receptor subtypes. British Journal of Anaesthesia. 109: 245-52. PMID 22628394 DOI: 10.1093/Bja/Aes136  0.512
2012 Ren K. Further evidence on a role of chemokines in injury-related pain hypersensitivity: commentary on a paper by Saika et al. (2012, this issue). European Journal of Pain (London, England). 16: 1209-10. PMID 22615147 DOI: 10.1002/j.1532-2149.2012.00173.x  0.42
2012 Xiong W, Cui T, Cheng K, Yang F, Chen SR, Willenbring D, Guan Y, Pan HL, Ren K, Xu Y, Zhang L. Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors. The Journal of Experimental Medicine. 209: 1121-34. PMID 22585736 DOI: 10.1084/Jem.20120242  0.741
2012 Guo W, Wang H, Zou S, Dubner R, Ren K. Chemokine signaling involving chemokine (C-C motif) ligand 2 plays a role in descending pain facilitation. Neuroscience Bulletin. 28: 193-207. PMID 22466130 DOI: 10.1007/s12264-012-1218-6  0.75
2012 Zhang Y, Meng X, Li A, Xin J, Berman BM, Lao L, Tan M, Ren K, Zhang RX. Electroacupuncture alleviates affective pain in an inflammatory pain rat model. European Journal of Pain (London, England). 16: 170-81. PMID 22323370 DOI: 10.1016/J.Ejpain.2011.07.002  0.49
2012 Lao L, Zhang Y, Shen X, Li A, Xin J, Berman B, Tan M, Ren K, Zhang R. P01.08. Acupuncture alleviates affective dimension of pain in a rat model of inflammatory hyperalgesia Bmc Complementary and Alternative Medicine. 12. DOI: 10.1186/1472-6882-12-S1-P8  0.426
2012 Zhang R, Meng X, Zhang Y, Shen X, Li A, Berman B, Ren K, Wei P, Lao L. OA08.03. Electroacupuncture alleviates hyperalgesia by inhibiting spinal interleukin-17 in an inflammatory pain rat model Bmc Complementary and Alternative Medicine. 12. DOI: 10.1186/1472-6882-12-S1-O31  0.362
2011 Yang K, Takeuchi K, Wei F, Dubner R, Ren K. Activation of group I mGlu receptors contributes to facilitation of NMDA receptor membrane current in spinal dorsal horn neurons after hind paw inflammation in rats. European Journal of Pharmacology. 670: 509-18. PMID 21951968 DOI: 10.1016/j.ejphar.2011.09.009  0.67
2011 Gu M, Miyoshi K, Dubner R, Guo W, Zou S, Ren K, Noguchi K, Wei F. Spinal 5-HT(3) receptor activation induces behavioral hypersensitivity via a neuronal-glial-neuronal signaling cascade. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 12823-36. PMID 21900561 DOI: 10.1523/JNEUROSCI.1564-11.2011  0.718
2011 Meng X, Zhang Y, Li A, Xin J, Lao L, Ren K, Berman BM, Tan M, Zhang RX. The effects of opioid receptor antagonists on electroacupuncture-produced anti-allodynia/hyperalgesia in rats with paclitaxel-evoked peripheral neuropathy. Brain Research. 1414: 58-65. PMID 21872220 DOI: 10.1016/J.Brainres.2011.08.004  0.501
2011 Li A, Zhang Y, Lao L, Xin J, Ren K, Berman BM, Zhang RX. Serotonin Receptor 2A/C Is Involved in Electroacupuncture Inhibition of Pain in an Osteoarthritis Rat Model. Evidence-Based Complementary and Alternative Medicine : Ecam. 2011: 619650. PMID 21799685 DOI: 10.1093/ecam/neq016  0.523
2011 Ren K, Dubner R. The role of trigeminal interpolaris-caudalis transition zone in persistent orofacial pain. International Review of Neurobiology. 97: 207-25. PMID 21708312 DOI: 10.1016/B978-0-12-385198-7.00008-4  0.638
2011 Zhang Y, Meng X, Li A, Xin J, Berman BM, Lao L, Tan M, Ren K, Zhang RX. Acupuncture alleviates the affective dimension of pain in a rat model of inflammatory hyperalgesia. Neurochemical Research. 36: 2104-10. PMID 21695393 DOI: 10.1007/S11064-011-0534-Y  0.501
2011 Guo W, Wang H, Zou S, Gu M, Watanabe M, Wei F, Dubner R, Huang GT, Ren K. Bone marrow stromal cells produce long-term pain relief in rat models of persistent pain. Stem Cells (Dayton, Ohio). 29: 1294-303. PMID 21630378 DOI: 10.1002/stem.667  0.821
2011 Zhang Y, Li A, Lao L, Xin J, Ren K, Berman BM, Zhang RX. Rostral ventromedial medulla μ, but not κ, opioid receptors are involved in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model. Brain Research. 1395: 38-45. PMID 21565329 DOI: 10.1016/j.brainres.2011.04.037  0.542
2011 Zhang Y, Li A, Xin J, Lao L, Ren K, Berman BM, Tan M, Zhang RX. Involvement of spinal serotonin receptors in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model. Neurochemical Research. 36: 1785-92. PMID 21556842 DOI: 10.1007/S11064-011-0495-1  0.498
2010 Wang H, Guo W, Yang K, Wei F, Dubner R, Ren K. Contribution of Primary Afferent Input to Trigeminal Astroglial Hyperactivity, Cytokine Induction and NMDA Receptor Phosphorylation. The Open Pain Journal. 2010: 144-152. PMID 21170295 DOI: 10.2174/1876386301003010144]  0.638
2010 Ren K, Dubner R. Interactions between the immune and nervous systems in pain. Nature Medicine. 16: 1267-76. PMID 20948535 DOI: 10.1038/nm.2234  0.593
2010 Lagraize SC, Guo W, Yang K, Wei F, Ren K, Dubner R. Spinal cord mechanisms mediating behavioral hyperalgesia induced by neurokinin-1 tachykinin receptor activation in the rostral ventromedial medulla. Neuroscience. 171: 1341-56. PMID 20888891 DOI: 10.1016/j.neuroscience.2010.09.040  0.698
2010 Bai G, Wei D, Zou S, Ren K, Dubner R. Inhibition of class II histone deacetylases in the spinal cord attenuates inflammatory hyperalgesia. Molecular Pain. 6: 51. PMID 20822541 DOI: 10.1186/1744-8069-6-51  0.566
2010 Guo W, Wang H, Zou S, Wei F, Dubner R, Ren K. Long lasting pain hypersensitivity following ligation of the tendon of the masseter muscle in rats: a model of myogenic orofacial pain. Molecular Pain. 6: 40. PMID 20633279 DOI: 10.1186/1744-8069-6-40  0.756
2010 Wei F, Dubner R, Zou S, Ren K, Bai G, Wei D, Guo W. Molecular depletion of descending serotonin unmasks its novel facilitatory role in the development of persistent pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8624-36. PMID 20573908 DOI: 10.1523/JNEUROSCI.5389-09.2010  0.713
2010 Ren K. Emerging role of astroglia in pain hypersensitivity. The Japanese Dental Science Review. 46: 86. PMID 20161683 DOI: 10.1016/j.jdsr.2009.10.005  0.493
2010 Ren K. Editorial: Neuron, Glia and Reciprocal Relationships in Pain Processing~!2009-10-22~!2010-02-25~!2010-05-07~! The Open Pain Journal. 3: 1-2. DOI: 10.2174/1876386301003020001  0.309
2009 Ren K. Neuron, Glia and Reciprocal Relationships in Pain Processing. The Open Pain Journal. 2: 7-31. PMID 21179400 DOI: 10.2174/1876386301003010001  0.49
2009 Khodorova A, Zou S, Ren K, Dubner R, Davar G, Strichartz G. Dual Roles for Endothelin-B Receptors in Modulating Adjuvant-Induced Inflammatory Hyperalgesia in Rats. The Open Pain Journal. 2: 30-40. PMID 20559459 DOI: 10.2174/1876386300902010030  0.612
2009 Shimizu K, Chai B, Lagraize SC, Wei F, Dubner R, Ren K. Microinjection of IL-1β into the trigeminal transition zone produces bilateral NMDA receptor-dependent orofacial hyperalgesia involving descending circuitry. The Open Pain Journal. 2: 76-83. PMID 20221418 DOI: 10.2174/1876386300902010076  0.634
2009 Shimizu K, Guo W, Wang H, Zou S, LaGraize SC, Iwata K, Wei F, Dubner R, Ren K. Differential involvement of trigeminal transition zone and laminated subnucleus caudalis in orofacial deep and cutaneous hyperalgesia: the effects of interleukin-10 and glial inhibitors. Molecular Pain. 5: 75. PMID 20025765 DOI: 10.1186/1744-8069-5-75  0.795
2009 Shoda E, Kitagawa J, Suzuki I, Nitta-Kubota I, Miyamoto M, Tsuboi Y, Kondo M, Masuda Y, Oi Y, Ren K, Iwata K. Increased phosphorylation of extracellular signal-regulated kinase in trigeminal nociceptive neurons following propofol administration in rats. The Journal of Pain : Official Journal of the American Pain Society. 10: 573-85. PMID 19398380 DOI: 10.1016/j.jpain.2008.11.013  0.611
2008 Wei F, Guo W, Zou S, Ren K, Dubner R. Supraspinal glial-neuronal interactions contribute to descending pain facilitation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10482-95. PMID 18923025 DOI: 10.1523/JNEUROSCI.3593-08.2008  0.696
2008 Ren K, Dubner R. Neuron-glia crosstalk gets serious: role in pain hypersensitivity. Current Opinion in Anaesthesiology. 21: 570-9. PMID 18784481 DOI: 10.1097/ACO.0b013e32830edbdf  0.644
2008 Yamazaki Y, Ren K, Shimada M, Iwata K. Modulation of paratrigeminal nociceptive neurons following temporomandibular joint inflammation in rats. Experimental Neurology. 214: 209-18. PMID 18778706 DOI: 10.1016/j.expneurol.2008.08.005  0.562
2008 Zhang RX, Liu B, Li A, Wang L, Ren K, Qiao JT, Berman BM, Lao L. Interleukin 1beta facilitates bone cancer pain in rats by enhancing NMDA receptor NR-1 subunit phosphorylation. Neuroscience. 154: 1533-8. PMID 18554806 DOI: 10.1016/j.neuroscience.2008.04.072  0.415
2008 Li A, Lao L, Wang Y, Xin J, Ren K, Berman BM, Tan M, Zhang R. Electroacupuncture activates corticotrophin-releasing hormone-containing neurons in the paraventricular nucleus of the hypothalammus to alleviate edema in a rat model of inflammation. Bmc Complementary and Alternative Medicine. 8: 20. PMID 18474100 DOI: 10.1186/1472-6882-8-20  0.466
2008 Zhang RX, Li A, Liu B, Wang L, Xin J, Ren K, Qiao JT, Berman BM, Lao L. Electroacupuncture attenuates bone-cancer-induced hyperalgesia and inhibits spinal preprodynorphin expression in a rat model. European Journal of Pain (London, England). 12: 870-8. PMID 18221900 DOI: 10.1016/j.ejpain.2007.12.006  0.415
2008 Zhang RX, Li A, Liu B, Wang L, Ren K, Zhang H, Berman BM, Lao L. IL-1ra alleviates inflammatory hyperalgesia through preventing phosphorylation of NMDA receptor NR-1 subunit in rats. Pain. 135: 232-9. PMID 17689191 DOI: 10.1016/j.pain.2007.05.023  0.377
2007 Li A, Wang Y, Xin J, Lao L, Ren K, Berman BM, Zhang RX. Electroacupuncture suppresses hyperalgesia and spinal Fos expression by activating the descending inhibitory system. Brain Research. 1186: 171-9. PMID 18001697 DOI: 10.1016/j.brainres.2007.10.022  0.485
2007 Zhang RX, Li A, Liu B, Wang L, Ren K, Qiao JT, Berman BM, Lao L. Electroacupuncture attenuates bone cancer pain and inhibits spinal interleukin-1 beta expression in a rat model. Anesthesia and Analgesia. 105: 1482-8, table of con. PMID 17959986 DOI: 10.1213/01.ane.0000284705.34629.c5  0.409
2007 Ren K, Dubner R. Pain facilitation and activity-dependent plasticity in pain modulatory circuitry: role of BDNF-TrkB signaling and NMDA receptors. Molecular Neurobiology. 35: 224-35. PMID 17917111 DOI: 10.1007/s12035-007-0028-8  0.633
2007 Li A, Zhang RX, Wang Y, Zhang H, Ren K, Berman BM, Tan M, Lao L. Corticosterone mediates electroacupuncture-produced anti-edema in a rat model of inflammation. Bmc Complementary and Alternative Medicine. 7: 27. PMID 17697336 DOI: 10.1186/1472-6882-7-27  0.399
2007 Guo W, Wang H, Watanabe M, Shimizu K, Zou S, LaGraize SC, Wei F, Dubner R, Ren K. Glial-cytokine-neuronal interactions underlying the mechanisms of persistent pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 6006-18. PMID 17537972 DOI: 10.1523/JNEUROSCI.0176-07.2007  0.8
2007 Li A, Lao L, Wang Y, Zhang H, Ren K, Berman BM, Zhang R. Interleukin-1ra inhibits Fos expression and hyperalgesia in rats. Neuroreport. 18: 495-8. PMID 17496810 DOI: 10.1097/WNR.0b013e3280586839  0.437
2006 Bi GQ, Bolshakov V, Bu G, Cahill CM, Chen ZF, Collingridge GL, Cooper RL, Coorssen JR, El-Husseini A, Galhardo V, Gan WB, Gu J, Inoue K, Isaac J, Iwata K, ... ... Ren K, et al. Recent advances in basic neurosciences and brain disease: from synapses to behavior. Molecular Pain. 2: 38. PMID 17196111 DOI: 10.1186/1744-8069-2-38  0.604
2006 Lao L, Fan AY, Zhang RX, Zhou A, Ma ZZ, Lee DY, Ren K, Berman B. Anti-hyperalgesic and anti-inflammatory effects of the modified Chinese herbal formula Huo Luo Xiao Ling Dan (HLXL) in rats. The American Journal of Chinese Medicine. 34: 833-44. PMID 17080548 DOI: 10.1142/S0192415X06004326  0.413
2006 Wang H, Wei F, Dubner R, Ren K. Selective distribution and function of primary afferent nociceptive inputs from deep muscle tissue to the brainstem trigeminal transition zone. The Journal of Comparative Neurology. 498: 390-402. PMID 16871539 DOI: 10.1002/cne.21062  0.716
2006 Ogawa A, Meng ID, Ren K, Imamura Y, Iwata K. Differential responses of rostral subnucleus caudalis and upper cervical dorsal horn neurons to mechanical and chemical stimulation of the parotid gland in rats. Brain Research. 1106: 123-33. PMID 16854383 DOI: 10.1016/j.brainres.2006.05.074  0.504
2006 Sugiyo S, Takemura M, Dubner R, Ren K. Demonstration of a trigeminothalamic pathway to the oval paracentral intralaminar thalamic nucleus and its involvement in the processing of noxious orofacial deep inputs. Brain Research. 1097: 116-22. PMID 16730672 DOI: 10.1016/j.brainres.2006.04.079  0.556
2006 Shimizu K, Asano M, Kitagawa J, Ogiso B, Ren K, Oki H, Matsumoto M, Iwata K. Phosphorylation of Extracellular Signal-Regulated Kinase in medullary and upper cervical cord neurons following noxious tooth pulp stimulation. Brain Research. 1072: 99-109. PMID 16442086 DOI: 10.1016/j.brainres.2005.12.040  0.579
2006 Guo W, Robbins MT, Wei F, Zou S, Dubner R, Ren K. Supraspinal brain-derived neurotrophic factor signaling: a novel mechanism for descending pain facilitation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 126-37. PMID 16399679 DOI: 10.1523/JNEUROSCI.3686-05.2006  0.752
2005 Zhang GG, Yu C, Lee W, Lao L, Ren K, Berman BM. Involvement of peripheral opioid mechanisms in electroacupuncture analgesia. Explore (New York, N.Y.). 1: 365-71. PMID 16781567 DOI: 10.1016/j.explore.2005.06.006  0.467
2005 Sugiyo S, Takemura M, Dubner R, Ren K. Trigeminal transition zone/rostral ventromedial medulla connections and facilitation of orofacial hyperalgesia after masseter inflammation in rats. The Journal of Comparative Neurology. 493: 510-23. PMID 16304628 DOI: 10.1002/cne.20797  0.649
2005 Kitagawa J, Tsuboi Y, Ogawa A, Ren K, Hitomi S, Saitoh K, Takahashi O, Masuda Y, Harada T, Hanzawa N, Kanda K, Iwata K. Involvement of dorsal column nucleus neurons in nociceptive transmission in aged rats. Journal of Neurophysiology. 94: 4178-87. PMID 16293592 DOI: 10.1152/jn.00243.2005  0.556
2005 Ren K, Novikova SI, He F, Dubner R, Lidow MS. Neonatal local noxious insult affects gene expression in the spinal dorsal horn of adult rats. Molecular Pain. 1: 27. PMID 16179088 DOI: 10.1186/1744-8069-1-27  0.609
2005 Zhang RX, Liu B, Wang L, Ren K, Qiao JT, Berman BM, Lao L. Spinal glial activation in a new rat model of bone cancer pain produced by prostate cancer cell inoculation of the tibia. Pain. 118: 125-36. PMID 16154703 DOI: 10.1016/j.pain.2005.08.001  0.418
2005 Sato T, Kitagawa J, Ren K, Tanaka H, Tanabe A, Watanabe T, Mitsuhashi Y, Iwata K. Activation of trigeminal intranuclear pathway in rats with temporomandibular joint inflammation. Journal of Oral Science. 47: 65-9. PMID 16050485 DOI: 10.2334/JOSNUSD.47.65  0.55
2005 Zhang RX, Wang L, Liu B, Qiao JT, Ren K, Berman BM, Lao L. Mu opioid receptor-containing neurons mediate electroacupuncture-produced anti-hyperalgesia in rats with hind paw inflammation. Brain Research. 1048: 235-40. PMID 15922310 DOI: 10.1016/j.brainres.2005.05.008  0.509
2005 Watanabe M, Guo W, Zou S, Sugiyo S, Dubner R, Ren K. Antibody array analysis of peripheral and blood cytokine levels in rats after masseter inflammation. Neuroscience Letters. 382: 128-33. PMID 15911135 DOI: 10.1016/j.neulet.2005.03.002  0.736
2005 Zhang RX, Liu B, Qiao JT, Wang L, Ren K, Berman BM, Lao L. Electroacupuncture suppresses spinal expression of neurokinin-1 receptors induced by persistent inflammation in rats. Neuroscience Letters. 384: 339-43. PMID 15908113 DOI: 10.1016/j.neulet.2005.05.001  0.508
2005 Zhang RX, Wang L, Wang X, Ren K, Berman BM, Lao L. Electroacupuncture combined with MK-801 prolongs anti-hyperalgesia in rats with peripheral inflammation. Pharmacology, Biochemistry, and Behavior. 81: 146-51. PMID 15894072 DOI: 10.1016/j.pbb.2005.03.002  0.492
2005 Anseloni VC, Ren K, Dubner R, Ennis M. A brainstem substrate for analgesia elicited by intraoral sucrose. Neuroscience. 133: 231-43. PMID 15893646 DOI: 10.1016/j.neuroscience.2005.01.055  0.824
2005 Liu B, Zhang RX, Wang L, Ren K, Qiao JT, Berman BM, Lao L. Effects of pertussis toxin on electroacupuncture-produced anti-hyperalgesia in inflamed rats. Brain Research. 1044: 87-92. PMID 15862793 DOI: 10.1016/j.brainres.2005.03.006  0.489
2005 Zhang RX, Lao L, Wang X, Fan A, Wang L, Ren K, Berman BM. Electroacupuncture attenuates inflammation in a rat model. Journal of Alternative and Complementary Medicine (New York, N.Y.). 11: 135-42. PMID 15750372 DOI: 10.1089/acm.2005.11.135  0.383
2005 Kitagawa J, Kanda K, Sugiura M, Tsuboi Y, Ogawa A, Shimizu K, Koyama N, Kamo H, Watanabe T, Ren K, Iwata K. Effect of chronic inflammation on dorsal horn nociceptive neurons in aged rats. Journal of Neurophysiology. 93: 3594-604. PMID 15659525 DOI: 10.1152/jn.01075.2004  0.503
2005 Renn CL, Guan Y, Guo W, Dubner R, Ren K. The AMPA Receptor in Descending Circuitry: Role in Activity-Dependent Plasticity Reviews in Analgesia. 8: 57-69. DOI: 10.3727/000000005783992908  0.784
2005 Guo W, Zou SP, Ikeda T, Dubner R, Ren K. Rapid and lasting increase in serine phosphorylation of rat spinal cord NMDAR1 and GluR1 subunits after peripheral inflammation Thalamus and Related Systems. 3: 9-18. DOI: 10.1017/S1472928805000026  0.526
2004 Dubner R, Ren K. Brainstem mechanisms of persistent pain following injury. Journal of Orofacial Pain. 18: 299-305. PMID 15636012  0.624
2004 Iwata K, Tsuboi Y, Shima A, Harada T, Ren K, Kanda K, Kitagawa J. Central neuronal changes after nerve injury: neuroplastic influences of injury and aging. Journal of Orofacial Pain. 18: 293-8. PMID 15636011  0.536
2004 Guo W, Wei F, Zou S, Robbins MT, Sugiyo S, Ikeda T, Tu JC, Worley PF, Dubner R, Ren K. Group I metabotropic glutamate receptor NMDA receptor coupling and signaling cascade mediate spinal dorsal horn NMDA receptor 2B tyrosine phosphorylation associated with inflammatory hyperalgesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9161-73. PMID 15483135 DOI: 10.1523/JNEUROSCI.3422-04.2004  0.747
2004 Tsuboi Y, Takeda M, Tanimoto T, Ikeda M, Matsumoto S, Kitagawa J, Teramoto K, Simizu K, Yamazaki Y, Shima A, Ren K, Iwata K. Alteration of the second branch of the trigeminal nerve activity following inferior alveolar nerve transection in rats. Pain. 111: 323-34. PMID 15363876 DOI: 10.1016/j.pain.2004.07.014  0.527
2004 Lao L, Zhang RX, Zhang G, Wang X, Berman BM, Ren K. A parametric study of electroacupuncture on persistent hyperalgesia and Fos protein expression in rats. Brain Research. 1020: 18-29. PMID 15312783 DOI: 10.1016/j.brainres.2004.01.092  0.464
2004 Zhang RX, Lao L, Wang L, Liu B, Wang X, Ren K, Berman BM. Involvement of opioid receptors in electroacupuncture-produced anti-hyperalgesia in rats with peripheral inflammation. Brain Research. 1020: 12-7. PMID 15312782 DOI: 10.1016/j.brainres.2004.05.067  0.466
2004 Zhang RX, Lao L, Wang X, Ren K, Berman BB. Electroacupuncture combined with indomethacin enhances antihyperalgesia in inflammatory rats. Pharmacology, Biochemistry, and Behavior. 78: 793-7. PMID 15301937 DOI: 10.1016/j.pbb.2004.05.010  0.441
2004 Ren K, Anseloni V, Zou SP, Wade EB, Novikova SI, Ennis M, Traub RJ, Gold MS, Dubner R, Lidow MS. Characterization of basal and re-inflammation-associated long-term alteration in pain responsivity following short-lasting neonatal local inflammatory insult. Pain. 110: 588-96. PMID 15288399 DOI: 10.1016/J.Pain.2004.04.006  0.798
2004 Guan Y, Guo W, Robbins MT, Dubner R, Ren K. Changes in AMPA receptor phosphorylation in the rostral ventromedial medulla after inflammatory hyperalgesia in rats. Neuroscience Letters. 366: 201-5. PMID 15276247 DOI: 10.1016/j.neulet.2004.05.051  0.818
2004 Anseloni V, Ren K, Dubner R, Ennis M. Ontogeny of analgesia elicited by non-nutritive suckling in acute and persistent neonatal rat pain models. Pain. 109: 507-13. PMID 15157713 DOI: 10.1016/j.pain.2004.02.031  0.794
2004 Iwata K, Masuda Y, Ren K. Trigeminal neuronal recording in animal models of orofacial pain. Methods in Molecular Medicine. 99: 123-37. PMID 15131334 DOI: 10.1385/1-59259-770-X:123  0.564
2003 Ikeda T, Terayama R, Jue SS, Sugiyo S, Dubner R, Ren K. Differential rostral projections of caudal brainstem neurons receiving trigeminal input after masseter inflammation. The Journal of Comparative Neurology. 465: 220-33. PMID 12949783 DOI: 10.1002/cne.10836  0.76
2003 Ogawa A, Ren K, Tsuboi Y, Morimoto T, Sato T, Iwata K. A new model of experimental parotitis in rats and its implication for trigeminal nociception Experimental Brain Research. 152: 307-316. PMID 12898097 DOI: 10.1007/s00221-003-1538-x  0.598
2003 Guan Y, Guo W, Zou SP, Dubner R, Ren K. Inflammation-induced upregulation of AMPA receptor subunit expression in brain stem pain modulatory circuitry. Pain. 104: 401-13. PMID 12855351 DOI: 10.1016/S0304-3959(03)00048-4  0.769
2002 Ren K, Dubner R. Descending modulation in persistent pain: an update. Pain. 100: 1-6. PMID 12435453 DOI: 10.1016/S0304-3959(02)00368-8  0.592
2002 Guo W, Zou S, Tal M, Ren K. Activation of spinal kainate receptors after inflammation: behavioral hyperalgesia and subunit gene expression. European Journal of Pharmacology. 452: 309-18. PMID 12359272 DOI: 10.1016/S0014-2999(02)02333-6  0.642
2002 Guo W, Zou S, Guan Y, Ikeda T, Tal M, Dubner R, Ren K. Tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord during the development and maintenance of inflammatory hyperalgesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6208-17. PMID 12122079 DOI: 10.1523/Jneurosci.22-14-06208.2002  0.785
2002 Terayama R, Dubner R, Ren K. The roles of NMDA receptor activation and nucleus reticularis gigantocellularis in the time-dependent changes in descending inhibition after inflammation. Pain. 97: 171-81. PMID 12031790 DOI: 10.1016/S0304-3959(02)00017-9  0.778
2002 Anseloni VC, Weng HR, Terayama R, Letizia D, Davis BJ, Ren K, Dubner R, Ennis M. Age-dependency of analgesia elicited by intraoral sucrose in acute and persistent pain models. Pain. 97: 93-103. PMID 12031783 DOI: 10.1016/S0304-3959(02)00010-6  0.815
2002 Miki K, Zhou QQ, Guo W, Guan Y, Terayama R, Dubner R, Ren K. Changes in gene expression and neuronal phenotype in brain stem pain modulatory circuitry after inflammation. Journal of Neurophysiology. 87: 750-60. PMID 11826044 DOI: 10.1152/Jn.00534.2001  0.844
2002 Guan Y, Terayama R, Dubner R, Ren K. Plasticity in excitatory amino acid receptor-mediated descending pain modulation after inflammation. The Journal of Pharmacology and Experimental Therapeutics. 300: 513-20. PMID 11805211 DOI: 10.1124/Jpet.300.2.513  0.809
2001 Imbe H, Iwata K, Zhou QQ, Zou S, Dubner R, Ren K. Orofacial deep and cutaneous tissue inflammation and trigeminal neuronal activation. Implications for persistent temporomandibular pain. Cells, Tissues, Organs. 169: 238-47. PMID 11455119 DOI: 10.1159/000047887  0.817
2001 Zhou QQ, Imbe H, Zou S, Dubner R, Ren K. Selective upregulation of the flip-flop splice variants of AMPA receptor subunits in the rat spinal cord after hindpaw inflammation. Brain Research. Molecular Brain Research. 88: 186-93. PMID 11295247 DOI: 10.1016/S0169-328X(01)00041-9  0.764
2001 Lidow MS, Song Z, Ren K. Long-term effects of short-lasting early local inflammatory insult. Neuroreport. 12: 399-403. PMID 11209957 DOI: 10.1097/00001756-200102120-00042  0.429
2001 Lao L, Zhang G, Wei F, Berman BM, Ren K. Electro-acupuncture attenuates behavioral hyperalgesia and selectively reduces spinal Fos protein expression in rats with persistent inflammation Journal of Pain. 2: 111-117. DOI: 10.1054/jpai.2001.19575  0.435
2000 Terayama R, Guan Y, Dubner R, Ren K. Activity-induced plasticity in brain stem pain modulatory circuitry after inflammation. Neuroreport. 11: 1915-9. PMID 10884043 DOI: 10.1097/00001756-200006260-00022  0.819
2000 Ren K, Wei1 F, Dubner R, Murphy A, Hoffman GE. Progesterone attenuates persistent inflammatory hyperalgesia in female rats: involvement of spinal NMDA receptor mechanisms. Brain Research. 865: 272-7. PMID 10821931 DOI: 10.1016/S0006-8993(00)02267-8  0.664
2000 Imbe H, Ren K. The up-regulation of preprodynorphin mRNA in trigeminoparabrachial neurons after inflammation. Neuroreport. 11: 845-7. PMID 10757531 DOI: 10.1097/00001756-200003200-00037  0.712
2000 Miki K, Iwata K, Tsuboi Y, Morimoto T, Kondo E, Dai Y, Ren K, Noguchi K. Dorsal column-thalamic pathway is involved in thalamic hyperexcitability following peripheral nerve injury: A lesion study in rats with experimental mononeuropathy Pain. 85: 263-271. PMID 10692627 DOI: 10.1016/S0304-3959(99)00279-1  0.641
2000 Qiu C, Sora I, Ren K, Uhl G, Dubner R. Enhanced delta-opioid receptor-mediated antinociception in mu-opioid receptor-deficient mice. European Journal of Pharmacology. 387: 163-9. PMID 10650156 DOI: 10.1016/S0014-2999(99)00813-4  0.782
2000 Ren K. An improved method for assessing mechanical allodynia in the rat. Physiology & Behavior. 67: 711-6. PMID 10604842 DOI: 10.1016/S0031-9384(99)00136-5  0.357
2000 Lao L, Zhang G, Berman BM, Wei F, Ren K. Effect of electroacupuncture on hyperalgesia and Fos protein expression in rats with persistent inflammation - a new animal model Clinical Acupuncture and Oriental Medicine. 1: 112-114. DOI: 10.1054/caom.2000.0043  0.374
2000 Qiu C, Sora I, Ren K, Uhl G, Dubner R. Erratum to: “Enhanced δ-opioid receptor-mediated antinociception in μ-opioid receptor-deficient mice” European Journal of Pharmacology. 397: 227. DOI: 10.1016/S0014-2999(00)00203-X  0.776
1999 Ren K, Dubner R. Inflammatory Models of Pain and Hyperalgesia. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 40: 111-118. PMID 11406689 DOI: 10.1093/ILAR.40.3.111  0.604
1999 Wei F, Zou S, Young A, Dubner R, Ren K. Effects of four herbal extracts on adjuvant-induced inflammation and hyperalgesia in rats. Journal of Alternative and Complementary Medicine (New York, N.Y.). 5: 429-36. PMID 10537242 DOI: 10.1089/ACM.1999.5.429  0.651
1999 Imbe H, Dubner R, Ren K. Masseteric inflammation-induced Fos protein expression in the trigeminal interpolaris/caudalis transition zone: contribution of somatosensory-vagal-adrenal integration. Brain Research. 845: 165-75. PMID 10536195 DOI: 10.1016/S0006-8993(99)01913-7  0.77
1999 Wei F, Dubner R, Ren K. Laminar-selective noradrenergic and serotoninergic modulation includes spinoparabrachial cells after inflammation. Neuroreport. 10: 1757-61. PMID 10501570 DOI: 10.1097/00001756-199906030-00024  0.668
1999 Dubner R, Ren K. Endogenous mechanisms of sensory modulation. Pain. S45-53. PMID 10491972 DOI: 10.1016/S0304-3959(99)00137-2  0.635
1999 Iwata K, Tashiro A, Tsuboi Y, Imai T, Sumino R, Morimoto T, Dubner R, Ren K. Medullary dorsal horn neuronal activity in rats with persistent temporomandibular joint and perioral inflammation. Journal of Neurophysiology. 82: 1244-53. PMID 10482744 DOI: 10.1152/Jn.1999.82.3.1244  0.798
1999 Zhou Q, Imbe H, Dubner R, Ren K. Persistent Fos protein expression after orofacial deep or cutaneous tissue inflammation in rats: implications for persistent orofacial pain. The Journal of Comparative Neurology. 412: 276-91. PMID 10441756 DOI: 10.1002/(SICI)1096-9861(19990920)412:2<276::AID-CNE7>3.0.CO;2-9  0.79
1999 Wei F, Dubner R, Ren K. Nucleus reticularis gigantocellularis and nucleus raphe magnus in the brain stem exert opposite effects on behavioral hyperalgesia and spinal Fos protein expression after peripheral inflammation. Pain. 80: 127-41. PMID 10204725 DOI: 10.1016/S0304-3959(98)00212-7  0.717
1999 MacArthur L, Ren K, Pfaffenroth E, Franklin E, Ruda MA. Descending modulation of opioid-containing nociceptive neurons in rats with peripheral inflammation and hyperalgesia. Neuroscience. 88: 499-506. PMID 10197770 DOI: 10.1016/S0306-4522(98)00204-8  0.608
1999 Imbe H, Ren K. Orofacial deep and cutaneous tissue inflammation differentially upregulates preprodynorphin mRNA in the trigeminal and paratrigeminal nuclei of the rat. Brain Research. Molecular Brain Research. 67: 87-97. PMID 10101236 DOI: 10.1016/S0169-328X(99)00040-6  0.705
1999 Wei F, Dubner R, Ren K. Dorsolateral funiculus-lesions unmask inhibitory or disfacilitatory mechanisms which modulate the effects of innocuous mechanical stimulation on spinal Fos expression after inflammation. Brain Research. 820: 112-6. PMID 10023038 DOI: 10.1016/S0006-8993(98)01359-6  0.691
1998 Wei F, Ren K, Dubner R. Inflammation-induced Fos protein expression in the rat spinal cord is enhanced following dorsolateral or ventrolateral funiculus lesions. Brain Research. 782: 136-41. PMID 9519257 DOI: 10.1016/S0006-8993(97)01253-5  0.673
1997 Ren K, Blass EM, Zhou Q, Dubner R. Suckling and sucrose ingestion suppress persistent hyperalgesia and spinal Fos expression after forepaw inflammation in infant rats. Proceedings of the National Academy of Sciences of the United States of America. 94: 1471-5. PMID 9037077 DOI: 10.1073/pnas.94.4.1471  0.637
1996 Ren K, Dubner R. Enhanced descending modulation of nociception in rats with persistent hindpaw inflammation. Journal of Neurophysiology. 76: 3025-37. PMID 8930252 DOI: 10.1152/JN.1996.76.5.3025  0.62
1995 Ren K, Ruda MA. Nitric oxide synthase-containing neurons in sensory ganglia of the rat are susceptible to capsaicin-induced cytotoxicity. Neuroscience. 65: 505-11. PMID 7539899 DOI: 10.1016/0306-4522(94)00510-C  0.499
1994 Ren K, Ruda MA. A comparative study of the calcium-binding proteins calbindin-D28K, calretinin, calmodulin and parvalbumin in the rat spinal cord. Brain Research. Brain Research Reviews. 19: 163-79. PMID 8061685 DOI: 10.1016/0165-0173(94)90010-8  0.503
1994 Ren K, Williams GM, Ruda MA, Dubner R. Inflammation and hyperalgesia in rats neonatally treated with capsaicin: effects on two classes of nociceptive neurons in the superficial dorsal horn. Pain. 59: 287-300. PMID 7892027 DOI: 10.1016/0304-3959(94)90082-5  0.827
1994 Nahin RL, Ren K, De León M, Ruda M. Primary sensory neurons exhibit altered gene expression in a rat model of neuropathic pain. Pain. 58: 95-108. PMID 7526320 DOI: 10.1016/0304-3959(94)90189-9  0.709
1992 Ren K, Hylden JL, Williams GM, Ruda MA, Dubner R. The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation. Pain. 50: 331-44. PMID 1454389 DOI: 10.1016/0304-3959(92)90039-E  0.836
1991 Ren K, Randich A, Gebhart GF. Spinal serotonergic and kappa opioid receptors mediate facilitation of the tail flick reflex produced by vagal afferent stimulation. Pain. 45: 321-9. PMID 1652118 DOI: 10.1016/0304-3959(91)90057-5  0.523
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