| Year |
Citation |
Score |
| 2022 |
Perego M, Fu S, Cao Y, Kossenkov A, Yao M, Alicea-Torres K, Liu W, Jiang Z, Chen Z, Fuchs SY, Zhou J, Gabrilovich DI. Mechanisms regulating transitory suppressive activity of neutrophils in newborns: PMNs-MDSCs in newborns. Journal of Leukocyte Biology. PMID 35726818 DOI: 10.1002/JLB.4HI0921-514RR |
0.373 |
|
| 2021 |
Chen DY, Khan N, Close BJ, Goel RK, Blum B, Tavares AH, Kenney D, Conway HL, Ewoldt JK, Chitalia VC, Crossland NA, Chen CS, Kotton DN, Baker SC, Fuchs SY, et al. SARS-CoV-2 disrupts proximal elements in the JAK-STAT pathway. Journal of Virology. JVI0086221. PMID 34260266 DOI: 10.1128/JVI.00862-21 |
0.304 |
|
| 2021 |
Alicea-Torres K, Sanseviero E, Gui J, Chen J, Veglia F, Yu Q, Donthireddy L, Kossenkov A, Lin C, Fu S, Mulligan C, Nam B, Masters G, Denstman F, Bennett J, ... Fuchs SY, et al. Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway. Nature Communications. 12: 1717. PMID 33741967 DOI: 10.1038/s41467-021-22033-2 |
0.323 |
|
| 2020 |
Odnokoz O, Yu P, Peck AR, Sun Y, Kovatich AJ, Hooke JA, Hu H, Mitchell EP, Rui H, Fuchs SY. Malignant cell-specific pro-tumorigenic role of type I interferon receptor in breast cancers. Cancer Biology & Therapy. 1-8. PMID 32378445 DOI: 10.1080/15384047.2020.1750297 |
0.353 |
|
| 2020 |
Singh S, Kumar S, Srivastava RK, Nandi A, Thacker G, Murali H, Kim S, Baldeon M, Tobias J, Blanco MA, Saffie R, Zaidi MR, Sinha S, Busino L, Fuchs SY, et al. Loss of ELF5-FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling. Nature Cell Biology. PMID 32284542 DOI: 10.1038/S41556-020-0495-Y |
0.32 |
|
| 2020 |
Fuchs S, Alicea-Torres KM, Gabrilovich DI. Abstract A72: IFNAR1 signaling regulates PMN-MDSCs immune suppressive activity in cancer Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-A72 |
0.369 |
|
| 2019 |
Gui J, Katlinski KV, Koumenis C, Diehl JA, Fuchs SY. The PKR-like endoplasmic reticulum kinase promotes the dissemination of Myc-induced leukemic cells. Molecular Cancer Research : McR. PMID 30902831 DOI: 10.1158/1541-7786.Mcr-19-0002 |
0.371 |
|
| 2017 |
Gui J, Zhao B, Lyu K, Tong W, Fuchs SY. Downregulation of the IFNAR1 chain of type 1 interferon receptor contributes to the maintenance of the hematopoietic stem cells. Cancer Biology & Therapy. 0. PMID 28678581 DOI: 10.1080/15384047.2017.1345395 |
0.375 |
|
| 2017 |
Zhao B, Bhattacharya S, Yu Q, Fuchs SY. Expression of the IFNAR1 chain of type 1 interferon receptor in benign cells protects against progression of acute leukemia. Leukemia & Lymphoma. 1-7. PMID 28503979 DOI: 10.1080/10428194.2017.1319053 |
0.38 |
|
| 2016 |
Katlinskaya YV, Katlinski KV, Yu Q, Ortiz A, Beiting DP, Brice A, Davar D, Sanders C, Kirkwood JM, Rui H, Xu X, Koumenis C, Diehl JA, Fuchs SY. Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression. Cell Reports. PMID 27052162 DOI: 10.1016/J.Celrep.2016.03.006 |
0.32 |
|
| 2015 |
Katlinskaya YV, Carbone CJ, Yu Q, Fuchs SY. Type 1 interferons contribute to the clearance of senescent cell. Cancer Biology & Therapy. 16: 1214-9. PMID 26046815 DOI: 10.1080/15384047.2015.1056419 |
0.312 |
|
| 2014 |
Carbone CJ, Fuchs SY. Eliminative signaling by Janus kinases: role in the downregulation of associated receptors. Journal of Cellular Biochemistry. 115: 8-16. PMID 23959845 DOI: 10.1002/Jcb.24647 |
0.437 |
|
| 2013 |
Zheng H, Gupta V, Patterson-Fortin J, Bhattacharya S, Katlinski K, Wu J, Varghese B, Carbone CJ, Aressy B, Fuchs SY, Greenberg RA. A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses. Cell Reports. 5: 180-93. PMID 24075985 DOI: 10.1016/J.Celrep.2013.08.025 |
0.735 |
|
| 2013 |
Fuchs SY. Hope and fear for interferon: the receptor-centric outlook on the future of interferon therapy. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 33: 211-25. PMID 23570388 DOI: 10.1089/jir.2012.0117 |
0.322 |
|
| 2013 |
Xu J, Sun D, Jiang J, Deng L, Zhang Y, Yu H, Bahl D, Langenheim JF, Chen WY, Fuchs SY, Frank SJ. The role of prolactin receptor in GH signaling in breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 27: 266-79. PMID 23192981 DOI: 10.1210/Me.2012-1297 |
0.41 |
|
| 2013 |
Bhattacharya S, HuangFu WC, Dong G, Qian J, Baker DP, Karar J, Koumenis C, Diehl JA, Fuchs SY. Anti-tumorigenic effects of Type 1 interferon are subdued by integrated stress responses. Oncogene. 32: 4214-21. PMID 23045272 DOI: 10.1038/onc.2012.439 |
0.428 |
|
| 2013 |
Koumenis C, Hart LS, Cunningham T, Dey S, Tameire F, Mills I, Ruggero D, Diehl AJ, Fuchs S. Abstract SY32-04: The translation initiation factor elF2α regulates cytoprotective autophagy in Myc-dependent lymphoma. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Sy32-04 |
0.409 |
|
| 2013 |
Carbone CJ, Varghese B, Zheng H, Fuchs SY. 33 Cytokine. 63: 251. DOI: 10.1016/J.Cyto.2013.06.036 |
0.741 |
|
| 2012 |
Carbone CJ, Zheng H, Bhattacharya S, Lewis JR, Reiter AM, Henthorn P, Zhang ZY, Baker DP, Ukkiramapandian R, Bence KK, Fuchs SY. Protein tyrosine phosphatase 1B is a key regulator of IFNAR1 endocytosis and a target for antiviral therapies. Proceedings of the National Academy of Sciences of the United States of America. 109: 19226-31. PMID 23129613 DOI: 10.1073/Pnas.1211491109 |
0.448 |
|
| 2012 |
Fuchs SY. Ubiquitination-mediated regulation of interferon responses. Growth Factors (Chur, Switzerland). 30: 141-8. PMID 22394219 DOI: 10.3109/08977194.2012.669382 |
0.316 |
|
| 2012 |
Cho IR, Oh M, Koh SS, Malilas W, Srisuttee R, Jhun BH, Pellegrini S, Fuchs SY, Chung YH. Hepatitis B virus X protein inhibits extracellular IFN-α-mediated signal transduction by downregulation of type I IFN receptor. International Journal of Molecular Medicine. 29: 581-6. PMID 22218495 DOI: 10.3892/ijmm.2012.879 |
0.318 |
|
| 2012 |
Huangfu WC, Qian J, Liu C, Liu J, Lokshin AE, Baker DP, Rui H, Fuchs SY. Inflammatory signaling compromises cell responses to interferon alpha. Oncogene. 31: 161-72. PMID 21666722 DOI: 10.1038/Onc.2011.221 |
0.372 |
|
| 2011 |
Zheng H, Qian J, Baker DP, Fuchs SY. Tyrosine phosphorylation of protein kinase D2 mediates ligand-inducible elimination of the Type 1 interferon receptor. The Journal of Biological Chemistry. 286: 35733-41. PMID 21865166 DOI: 10.1074/jbc.M111.263608 |
0.463 |
|
| 2011 |
Zheng H, Qian J, Carbone CJ, Leu NA, Baker DP, Fuchs SY. Vascular endothelial growth factor-induced elimination of the type 1 interferon receptor is required for efficient angiogenesis. Blood. 118: 4003-6. PMID 21832278 DOI: 10.1182/Blood-2011-06-359745 |
0.338 |
|
| 2011 |
Bhattacharya S, Zheng H, Tzimas C, Carroll M, Baker DP, Fuchs SY. Bcr-abl signals to desensitize chronic myeloid leukemia cells to IFNα via accelerating the degradation of its receptor. Blood. 118: 4179-87. PMID 21821707 DOI: 10.1182/Blood-2010-12-325373 |
0.441 |
|
| 2011 |
Qian J, Zheng H, Huangfu WC, Liu J, Carbone CJ, Leu NA, Baker DP, Fuchs SY. Pathogen recognition receptor signaling accelerates phosphorylation-dependent degradation of IFNAR1. Plos Pathogens. 7: e1002065. PMID 21695243 DOI: 10.1371/Journal.Ppat.1002065 |
0.409 |
|
| 2011 |
Bhattacharya S, Qian J, Tzimas C, Baker DP, Koumenis C, Diehl JA, Fuchs SY. Role of p38 protein kinase in the ligand-independent ubiquitination and down-regulation of the IFNAR1 chain of type I interferon receptor. The Journal of Biological Chemistry. 286: 22069-76. PMID 21540188 DOI: 10.1074/Jbc.M111.238766 |
0.441 |
|
| 2011 |
Zheng H, Qian J, Varghese B, Baker DP, Fuchs S. Ligand-stimulated downregulation of the alpha interferon receptor: role of protein kinase D2. Molecular and Cellular Biology. 31: 710-20. PMID 21173164 DOI: 10.1128/Mcb.01154-10 |
0.764 |
|
| 2011 |
Hart LS, Cunningham T, Datta T, Liu H, Koong AC, Fuchs S, Diehl JA, Ruggero D, Koumenis C. Abstract 2078: PERK-mediated autophagy promotes Myc-induced transformation and tumorigenesis Cancer Research. 71: 2078-2078. DOI: 10.1158/1538-7445.Am2011-2078 |
0.362 |
|
| 2010 |
HuangFu WC, Qian J, Liu C, Rui H, Fuchs SY. Melanoma cell-secreted soluble factor that stimulates ubiquitination and degradation of the interferon alpha receptor and attenuates its signaling. Pigment Cell & Melanoma Research. 23: 838-40. PMID 21644263 DOI: 10.1111/J.1755-148X.2010.00770.X |
0.386 |
|
| 2010 |
Huangfu WC, Fuchs SY. Ubiquitination-dependent regulation of signaling receptors in cancer. Genes & Cancer. 1: 725-34. PMID 21127735 DOI: 10.1177/1947601910382901 |
0.429 |
|
| 2010 |
Varghese B, Swaminathan G, Plotnikov A, Tzimas C, Yang N, Rui H, Fuchs SY. Prolactin inhibits activity of pyruvate kinase M2 to stimulate cell proliferation. Molecular Endocrinology (Baltimore, Md.). 24: 2356-65. PMID 20962042 DOI: 10.1210/Me.2010-0219 |
0.753 |
|
| 2010 |
Bhattacharya S, HuangFu WC, Liu J, Veeranki S, Baker DP, Koumenis C, Diehl JA, Fuchs SY. Inducible priming phosphorylation promotes ligand-independent degradation of the IFNAR1 chain of type I interferon receptor. The Journal of Biological Chemistry. 285: 2318-25. PMID 19948722 DOI: 10.1074/Jbc.M109.071498 |
0.457 |
|
| 2010 |
Fuchs SY. SS10-2 Phosphorylation-dependent regulation of IFNAR1 stability and signaling Cytokine. 52: 78. DOI: 10.1016/j.cyto.2010.07.324 |
0.314 |
|
| 2010 |
Zheng H, Qian J, Varghese B, Baker DP, Fuchs S. PS2-36 Limiting cellular responses to interferon alpha: Role of protein kinase D2 Cytokine. 52: 58. DOI: 10.1016/J.Cyto.2010.07.241 |
0.717 |
|
| 2010 |
HuangFu W, Qian J, Liu C, Liu J, Ilyin V, Baker DP, Loksin AE, Rui H, Fuchs S. PS1-55 Cytokine signaling compromises the sensitivity of melanoma to Type I interferons Cytokine. 52: 28-29. DOI: 10.1016/J.Cyto.2010.07.127 |
0.338 |
|
| 2009 |
Liu J, Carvalho LP, Bhattacharya S, Carbone CJ, Kumar KG, Leu NA, Yau PM, Donald RG, Weiss MJ, Baker DP, McLaughlin KJ, Scott P, Fuchs SY. Mammalian casein kinase 1alpha and its leishmanial ortholog regulate stability of IFNAR1 and type I interferon signaling. Molecular and Cellular Biology. 29: 6401-12. PMID 19805514 DOI: 10.1128/Mcb.00478-09 |
0.46 |
|
| 2009 |
Plotnikov A, Varghese B, Tran TH, Liu C, Rui H, Fuchs SY. Impaired turnover of prolactin receptor contributes to transformation of human breast cells. Cancer Research. 69: 3165-72. PMID 19276348 DOI: 10.1158/0008-5472.Can-08-4033 |
0.736 |
|
| 2009 |
Liu J, HuangFu WC, Kumar KG, Qian J, Casey JP, Hamanaka RB, Grigoriadou C, Aldabe R, Diehl JA, Fuchs SY. Virus-induced unfolded protein response attenuates antiviral defenses via phosphorylation-dependent degradation of the type I interferon receptor. Cell Host & Microbe. 5: 72-83. PMID 19154989 DOI: 10.1016/J.Chom.2008.11.008 |
0.374 |
|
| 2008 |
Frank SJ, Fuchs SY. Modulation of growth hormone receptor abundance and function: roles for the ubiquitin-proteasome system. Biochimica Et Biophysica Acta. 1782: 785-94. PMID 18586085 DOI: 10.1016/J.Bbadis.2008.06.001 |
0.342 |
|
| 2008 |
Varghese B, Barriere H, Carbone CJ, Banerjee A, Swaminathan G, Plotnikov A, Xu P, Peng J, Goffin V, Lukacs GL, Fuchs SY. Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway. Molecular and Cellular Biology. 28: 5275-87. PMID 18573876 DOI: 10.1128/Mcb.00350-08 |
0.763 |
|
| 2008 |
Kumar KG, Varghese B, Banerjee A, Baker DP, Constantinescu SN, Pellegrini S, Fuchs SY. Basal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motif. The Journal of Biological Chemistry. 283: 18566-72. PMID 18474601 DOI: 10.1074/Jbc.M800991200 |
0.767 |
|
| 2008 |
Plotnikov A, Li Y, Tran TH, Tang W, Palazzo JP, Rui H, Fuchs SY. Oncogene-mediated inhibition of glycogen synthase kinase 3 beta impairs degradation of prolactin receptor. Cancer Research. 68: 1354-61. PMID 18316598 DOI: 10.1158/0008-5472.Can-07-6094 |
0.403 |
|
| 2008 |
Swaminathan G, Varghese B, Thangavel C, Carbone CJ, Plotnikov A, Kumar KG, Jablonski EM, Clevenger CV, Goffin V, Deng L, Frank SJ, Fuchs SY. Prolactin stimulates ubiquitination, initial internalization, and degradation of its receptor via catalytic activation of Janus kinase 2. The Journal of Endocrinology. 196: R1-7. PMID 18252943 DOI: 10.1677/Joe-07-0554 |
0.772 |
|
| 2008 |
Swaminathan G, Varghese B, Fuchs SY. Regulation of prolactin receptor levels and activity in breast cancer. Journal of Mammary Gland Biology and Neoplasia. 13: 81-91. PMID 18204982 DOI: 10.1007/S10911-008-9068-6 |
0.737 |
|
| 2008 |
Liu J, Plotnikov A, Banerjee A, Suresh Kumar KG, Ragimbeau J, Marijanovic Z, Baker DP, Pellegrini S, Fuchs SY. Ligand-independent pathway that controls stability of interferon alpha receptor. Biochemical and Biophysical Research Communications. 367: 388-93. PMID 18166147 DOI: 10.1016/j.bbrc.2007.12.137 |
0.487 |
|
| 2008 |
Liu J, HuangFu W, Kumar KGS, Casey JP, Hamanaka R, Grigoriadou C, Aldabe R, Diehl JA, Fuchs SY. 371 Virus-induced unfolded protein response attenuates anti-viral defenses via phosphorylation-dependent ubiquitination and degradation of Type I interferon receptor Cytokine. 43: 331-331. DOI: 10.1016/J.Cyto.2008.07.456 |
0.323 |
|
| 2007 |
Kumar KG, Barriere H, Carbone CJ, Liu J, Swaminathan G, Xu P, Li Y, Baker DP, Peng J, Lukacs GL, Fuchs SY. Site-specific ubiquitination exposes a linear motif to promote interferon-alpha receptor endocytosis. The Journal of Cell Biology. 179: 935-50. PMID 18056411 DOI: 10.1083/Jcb.200706034 |
0.459 |
|
| 2007 |
Kumar KG, Liu J, Li Y, Yu D, Thomas-Tikhonenko A, Herlyn M, Fuchs SY. Raf inhibitor stabilizes receptor for the type I interferon but inhibits its anti-proliferative effects in human malignant melanoma cells. Cancer Biology & Therapy. 6: 1437-41. PMID 17873516 DOI: 10.4161/Cbt.6.9.4569 |
0.399 |
|
| 2007 |
Deng L, He K, Wang X, Yang N, Thangavel C, Jiang J, Fuchs SY, Frank SJ. Determinants of growth hormone receptor down-regulation. Molecular Endocrinology (Baltimore, Md.). 21: 1537-51. PMID 17488973 DOI: 10.1210/Me.2007-0138 |
0.432 |
|
| 2007 |
Liu J, Kumar KGS, Carvalho L, Donald RGK, Scott P, Fuchs SY. 89 Regulation of Type I Interferon Receptor Stability and Signaling by Casein Kinase 1-alpha and its Leishmania Orthologue Cytokine. 39: 25-25. DOI: 10.1016/J.Cyto.2007.07.094 |
0.4 |
|
| 2006 |
Malakhova OA, Kim KI, Luo JK, Zou W, Kumar KG, Fuchs SY, Shuai K, Zhang DE. UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity. The Embo Journal. 25: 2358-67. PMID 16710296 DOI: 10.1038/Sj.Emboj.7601149 |
0.405 |
|
| 2006 |
Marijanovic Z, Ragimbeau J, Kumar KG, Fuchs SY, Pellegrini S. TYK2 activity promotes ligand-induced IFNAR1 proteolysis. The Biochemical Journal. 397: 31-8. PMID 16551269 DOI: 10.1042/BJ20060272 |
0.452 |
|
| 2006 |
Li Y, Clevenger CV, Minkovsky N, Kumar K, Raghunath PN, Tomaszewski JE, Spiegelman VS, Fuchs SY. Stabilization of prolactin receptor in breast cancer cells Oncogene. 25: 1896-1902. PMID 16278670 DOI: 10.1038/Sj.Onc.1209214 |
0.341 |
|
| 2005 |
Fuchs SY. De-regulation of ubiquitin-dependent proteolysis and the pathogenesis of malignant melanoma. Cancer Metastasis Reviews. 24: 329-38. PMID 15986141 DOI: 10.1007/s10555-005-1581-0 |
0.321 |
|
| 2004 |
Kumar KG, Krolewski JJ, Fuchs SY. Phosphorylation and specific ubiquitin acceptor sites are required for ubiquitination and degradation of the IFNAR1 subunit of type I interferon receptor. The Journal of Biological Chemistry. 279: 46614-20. PMID 15337770 DOI: 10.1074/Jbc.M407082200 |
0.391 |
|
| 2004 |
Li Y, Kumar KG, Tang W, Spiegelman VS, Fuchs SY. Negative regulation of prolactin receptor stability and signaling mediated by SCF(beta-TrCP) E3 ubiquitin ligase. Molecular and Cellular Biology. 24: 4038-48. PMID 15082796 DOI: 10.1128/MCB.24.9.4038-4048.2004 |
0.363 |
|
| 2004 |
Li Y, Gazdoiu S, Pan ZQ, Fuchs SY. Stability of homologue of Slimb F-box protein is regulated by availability of its substrate. The Journal of Biological Chemistry. 279: 11074-80. PMID 14707120 DOI: 10.1074/Jbc.M312301200 |
0.315 |
|
| 2003 |
Kumar KG, Tang W, Ravindranath AK, Clark WA, Croze E, Fuchs SY. SCF(HOS) ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-alpha receptor. The Embo Journal. 22: 5480-90. PMID 14532120 DOI: 10.1093/emboj/cdg524 |
0.484 |
|
| 2002 |
Fuchs SY. The role of ubiquitin-proteasome pathway in oncogenic signaling. Cancer Biology & Therapy. 1: 337-41. PMID 12432242 DOI: 10.4161/Cbt.1.4.6113 |
0.348 |
|
| 2002 |
Spiegelman VS, Tang W, Chan AM, Igarashi M, Aaronson SA, Sassoon DA, Katoh M, Slaga TJ, Fuchs SY. Induction of homologue of Slimb ubiquitin ligase receptor by mitogen signaling. The Journal of Biological Chemistry. 277: 36624-30. PMID 12151397 DOI: 10.1074/Jbc.M204524200 |
0.355 |
|
| 2001 |
Zenke G, Strittmatter U, Fuchs S, Quesniaux VF, Brinkmann V, Schuler W, Zurini M, Enz A, Billich A, Sanglier JJ, Fehr T. Sanglifehrin A, a novel cyclophilin-binding compound showing immunosuppressive activity with a new mechanism of action. Journal of Immunology (Baltimore, Md. : 1950). 166: 7165-71. PMID 11390463 DOI: 10.4049/Jimmunol.166.12.7165 |
0.322 |
|
| 2000 |
Fuchs SY, Tappin I, Ronai Z. Stability of the ATF2 transcription factor is regulated by phosphorylation and dephosphorylation. The Journal of Biological Chemistry. 275: 12560-4. PMID 10777545 DOI: 10.1074/Jbc.275.17.12560 |
0.361 |
|
| 1999 |
Adler V, Yin Z, Fuchs SY, Benezra M, Rosario L, Tew KD, Pincus MR, Sardana M, Henderson CJ, Wolf CR, Davis RJ, Ronai Z. Regulation of JNK signaling by GSTp. The Embo Journal. 18: 1321-34. PMID 10064598 DOI: 10.1093/Emboj/18.5.1321 |
0.335 |
|
| 1998 |
Fuchs SY, Fried VA, Ronai Z. Stress-activated kinases regulate protein stability. Oncogene. 17: 1483-90. PMID 9779995 DOI: 10.1038/Sj.Onc.1202184 |
0.365 |
|
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